ライフサイエンスコーパス: tight junction protein

1 ssion of Claudin-2, a cation-channel-forming tight junction protein.

2 d by Muller cells, and zonula occludens-1, a tight-junction protein.

3 essed for barrier function and expression of tight junction proteins.

4 lation of adhesion molecules and decrease in tight junction proteins.

5 PDZ-domain protein that associates with many tight junction proteins.

6 ITC)-labeled markers, and immunostaining for tight junction proteins.

7 sed by disruptions in adherens junctions and tight junction proteins.

8 licating electrostatic interactions with the tight junction proteins.

9 ssion and altered localization of intestinal tight junction proteins.

10 c activation and tyrosine phosphorylation of tight junction proteins.

11 oproteinase 9 expression and reduced loss of tight junction proteins.

12 Src family kinases/FAK, and down-regulating tight junction proteins.

13 dysregulated expression and localization of tight junction proteins.

14 mma attenuated HIV-mediated dysregulation of tight junction proteins.

15 companied by decreased surface expression of tight junction proteins.

16 -dependent pathways to upregulate epithelial tight junction proteins.

17 ocyte-vascular coupling and enhanced loss of tight junction proteins.

18 roteolytic activity on basement membrane and tight junction proteins.

19 reased intestinal permeability and decreased tight junction proteins.

20 induced breakdown of the BBB and cleavage of tight-junction proteins.

21 s the epithelium without gross alteration in tight-junction proteins.

22 protein Yes-associated protein 2 (YAP2) and tight junction protein 1 (TJP1 or ZO-1), uncovering inte

23 ZO-1 (Zona occludens 1), encoded by the tight junction protein 1 (TJP1) gene, is a regulator of

24 cological inhibition of GCS caused levels of tight junction protein 1 (TJP1) to decrease.

25 pe and organisation caused by truncations in Tight Junction Protein 1a (ZO-1a).

26 vo requires an intracellular scaffold called Tight Junction Protein 1b (Tjp1b).

27 the mRNA expression of cadherin-1 (CDH1) and tight junction protein 2 (TJP2), two primary components

28 ransporters ABCB4, ABCB11, ATP8B1, ABCC2 and tight junction protein 2 (TJP2).

29 how that protein-truncating mutations in the tight junction protein 2 gene (TJP2) cause failure of pr

30 (DSC)2, occludin (OCLN), desmoglein (DSG)1, tight junction protein 2, and gap junction protein alpha

31 Among these were tight junction protein-2 (2.2-fold increase, P = .019),

32 RB6-8C5, but not 1A8, display: 1) intact BBB tight junction proteins; 2) reduced CNS vascular permeab

33 Pals1 binds Patj (Pals1-associated tight-junction protein), a multi-PDZ-domain protein that

34 ermeability by inhibiting IL-6 and modulates tight junction proteins after ischemia.

35 The expression of several tight junction proteins also was decreased, whereas the

36 rocyte activation, cerebral endothelial cell tight junction protein alterations and CNS vascular perm

37 ry pathology in the intestine, gut leaching, tight junction protein alterations and increased oxidati

38 diaphragms by demonstrating the presence of tight junction proteins, although slit diaphragms lack t

39 Here we identify the angiomotin-family tight junction protein AMOTL2 as a novel activator of LA

40 Here we identify IFITM1 as a hepatocyte tight junction protein and a potent anti-HCV effector mo

41 Expression of tight junction protein and regular morphology was observ

42 that CD8 T cells initiate disruption of BBB tight junction proteins and CNS vascular permeability in

43 hat are coordinated with other transmembrane tight junction proteins and cytosolic scaffold proteins.

44 1) form tight junctions, 2) express typical tight junction proteins and electrolyte transporters, 3)

45 nal epithelium by decrease/redistribution of tight junction proteins and endoplasmic reticulum stress

46 The endothelium expresses high levels of tight junction proteins and functional efflux pumps, and

47 ient asthmatic mice resulted in dysregulated tight junction proteins and increased lung permeability.

48 EP-1 can modify the phosphorylation state of tight junction proteins and play a role in regulating pe

49 function was evaluated by immunostaining for tight junction proteins and quantifying the permeability

50 BBB by regulating the proper localization of tight junction proteins and raise the possibility that e

51 tau values, suggesting that loss of cortical tight junction proteins and synaptic degeneration is pre

52 a negative correlation between the amount of tight junction proteins and the amounts of insoluble Alz

53 MMPs degrade extracellular matrix and cleave tight-junction proteins and cytokines, modulating their

54 e protein (CLAMP), which resembles mammalian tight-junction proteins and localizes to secretory organ

55 We found that claudin-1, a tight junction protein, and small proline-rich (Sprr2) p

56 , analyzed levels of messenger RNAs encoding tight junction proteins, and performed H&E staining and

57 ransfer constant in brain regions, and IL-6, tight junction proteins, and plasmalemma vesicle protein

58 C, the protease-activated receptor PAR2, the tight junction proteins, and the profilaggrin polypeptid

59 he N terminus were enriched in transmembrane tight junction proteins, and those proximal to the C ter

60 Transepithelial electrical resistance and tight junction protein architecture were studied in cult

61 In addition, we show that tight-junction proteins are disintegrated in the PCFT mu

62 hich zonal occludens-1 and claudin-3, apical tight-junction proteins, are mislocalized.

63 MMP9 expression, and changes in endothelial tight junction proteins as well as adhesion molecules.

64 tudy identified occludin (OCLN), an integral tight junction protein, as one of the key factors for HC

65 This reflects substantial reductions in tight junction proteins associated with "leaky" nephron

66 tion and actomyosin contractions concentrate tight junction proteins at the breach, which repairs the

67 The expression of tight junction proteins between adjacent endothelial cel

68 romise the steady-state distribution of most tight junction proteins but results in increased transep

69 Claudin-18.1 is the only known lung-specific tight junction protein, but its contribution to airway b

70 luorescent assessments of zonula occludens-1 tight junction protein cellular distribution were conduc

71 Unlike its homologous tight junction protein cingulin, paracingulin has been i

72 The tight junction protein claudin 1 (Cldn-1) has been repor

73 ch as the microRNAs miR-217 and miR-122, the tight junction protein claudin c, the gene fam136a, and

74 ng numerous host cell factors, including the tight junction protein claudin-1 (CLDN1).

75 with decreases in the intestinal epithelial tight junction protein claudin-1 (CLDN1).

76 cytes, and it was recently reported that the tight junction protein claudin-1 is a critical HCV entry

77 Expression of the tight junction protein claudin-1 is dysregulated in colo

78 duces down-regulation of the barrier-forming tight junction protein claudin-1.

79 To elucidate the role of the tight junction protein claudin-10 in TAL function, we ge

80 expression of CLDN10, the gene encoding the tight junction protein Claudin-10, show enhanced paracel

81 tion of the permeability-associated, "leaky" tight junction protein claudin-2 at intercellular juncti

82 was decreased induction of the pore-forming tight junction protein claudin-2 in STAT6(-/-) mice.

83 The tight junction protein claudin-2 is upregulated in infla

84 Despite loss of the tight junction protein claudin-2, KO mice had preserved

85 -22-dependent upregulation of the epithelial tight junction protein claudin-2.

86 pithelial integrity indicated by loss of the tight junction protein claudin-3 was not observed during

87 I/R injury caused a loss of the tight junction protein claudin-3, which was ameliorated

88 hether differences in lung expression of the tight junction protein claudin-4 are associated with alv

89 d reduced expression of the endothelial cell tight junction protein claudin-5 (Cldn5) and abnormal bl

90 rain barrier (BBB) integrity through loss of tight junction protein claudin-5 (cldn5) in male mice, p

91 Moreover, levels of the tight junction protein claudin-5 were increased with nor

92 tenin and attachment to the promoter for the tight junction protein claudin-5, with concomitant reduc

93 breakdown and downregulation of the specific tight junction proteins claudin-1 and -3 in adult brain

94 ain 042 induced aberrant localization of the tight junction proteins claudin-1 and, to a lesser degre

95 13 correlated with altered expression of the tight junction proteins claudin-2, occludin, and ZO-1.

96 e, we identify the endothelial transmembrane tight junction proteins claudin-5 (CLN-5) and occludin (

97 The tight junction proteins claudin-5 and occludin showed re

98 scavenger receptor class B member I, and the tight-junction proteins claudin-1 and occludin have been

99 a reduction of the cerebral endothelial cell tight-junction proteins claudin-5 and occludin.

100 neutrophil accumulation, and localization of tight junction proteins (claudin-1, ZO-1) were visualize

101 and a very weak nominal association with the tight junction protein, claudin-5, has previously been i

102 By quantifying the amounts of major tight junction proteins, claudin-5 and occludin, in 12 b

103 increased BBB integrity (elevated levels of tight-junction protein, Claudin 5, and reduced S100B lev

104 Interestingly, we identified the tight junction protein claudin1 as a regulator of these

105 h is linked to significant downregulation of tight junction protein claudin5 in Lrp5(-/-) vessels.

106 ling controls junctional localisation of the tight junction protein CLDN5 and junction stability via

107 stress alters BBB integrity through loss of tight junction protein Cldn5, promoting peripheral IL-6

108 ral analysis revealed distinct intercellular tight junction protein complexes and immunocytochemistry

109 This effect was unrelated to changes in tight junction protein content.

110 In the kidney, tight junction proteins contribute to segment specific s

111 n or intracellular redistribution of several tight junction proteins, did not affect degradation of c

112 urther mechanistic studies show that reduced tight junction proteins, diminished AQP4 expression, and

113 thiocyanate-labeled dextran 4kDa (FD4) flux, tight junction protein distribution, and protein abundan

114 e permeability of HBMEC as well as prevented tight junction protein down-regulation of ZO-1, claudin-

115 oduct 2-deoxy-d-ribose cooperatively repress tight junction proteins, driving permeability.

116 ates paracellular permeability by remodeling tight junction protein dynamic behavior and intermolecul

117 emodeling contributes to barrier regulation, tight junction protein dynamic behavior was assessed by

118 In this study, we measure tight junction protein dynamics in live confluent Madin-

119 s accompanied by increased expression of the tight junction protein e-cadherin and sustained down reg

120 , epithelial cytokeratins (e.g., CK-19), and tight junction proteins (e.g., ZO-1), and impaired their

121 rbated the TGF-beta-induced dysregulation of tight junction proteins, E-cadherin and N-cadherin expre

122 It uses some claudin tight junction proteins (eg, claudin-4) as receptors to

123 molog in zebrafish elevated transcription of tight junction protein-encoding genes and increased zebr

124 metalloproteinases (MMPs), which degrade the tight junction proteins essential for maintaining BBB in

125 hesion molecule-A (JAM-A) is an adherens and tight junction protein expressed by endothelial and epit

126 lt was of focal nature and led to changes in tight junction protein expression and architecture.

127 flammatory diseases by regulating intestinal tight junction protein expression and barrier function.

128 OX-2 in the ileum is a critical modulator of tight junction protein expression and intestinal barrier

129 romised blood-brain barrier permeability and tight junction protein expression in the offspring at pr

130 Tight junction protein expression was measured by Wester

131 Barrier function and tight junction protein expression were assessed.

132 Alterations of tight junction protein expression were associated with i

133 MET-1 also preserved cecum tight junction protein expression, and reduced S. typhim

134 concentrations of Hcy showed a reduction of tight junction protein expression, increased FITC dextra

135 tic laminin decreases aquaporin-4 (AQP4) and tight junction protein expression.

136 blood-brain barrier (BBB) and alterations of tight junction protein expression.

137 is played only a partial role in maintaining tight junction protein expression.

138 e represses permeability-promoting claudin-2 tight-junction protein expression through an IL-10RA-dep

139 ed for changes in gut permeability, BTL, and tight-junction protein expression, immune cell recruitme

140 ctions (matrilysis) as well as adherence and tight junction proteins for degradation.

141 osely with one another through transmembrane tight junction proteins forming the blood-brain barrier.

142 , we identified a homozygous mutation in the tight-junction protein gene JAM3 in a large consanguineo

143 nd/or redistribution of three representative tight junction proteins (ie, zonula occludens-1, Occludi

144 nd dynamics, revealing a novel role for this tight junction protein in early brain development.

145 Our studies identify a novel role of a tight junction protein in the development and progressio

146 Thus, loss of cortical tight junction proteins in Alzheimer's disease is associ

147 ous glucocorticoids alters the expression of tight junction proteins in the cerebral cortex of sheep.

148 These caused deregulation of tight junction proteins in the endothelia.

149 ded to be higher, whereas gene expression of tight junction proteins in the ileum was significantly d

150 e a novel in vivo model to study the role of tight junction proteins in the remodeling of the biliary

151 In addition, the amount of tight junction proteins in these areas correlated positi

152 d the cell-surface distribution of these two tight junction proteins in various hepatic cell lines, i

153 or the junctional-adhesion-molecule-2, a key tight-junction protein in blood-brain-barrier permeabili

154 the hypoxia-induced decrease of occludin, a tight junction protein, in the OIR rat retina and in cul

155 The expression of other tight junction proteins (including ZO-1) was not associa

156 sed blood-brain barrier dysfunction, loss of tight junction proteins, increased endothelial stress fi

157 egrated model in which dynamic regulation of tight junction protein interactions determines barrier f

158 ted diarrhea results from NF-kappaB-mediated tight junction protein internalization and increased par

159 nes of clinical significance such as OCLN, a tight junction protein involved in hepatitis C viral ent

160 his study, we show that the loss of cortical tight junction proteins is a common event in Alzheimer's

161 he sub-cellular distribution of adherens and tight junction proteins is perturbed in mutant lung epit

162 Whether slit diaphragms also contain tight junction proteins is unknown.

163 at junctional adhesion molecule A (JAM-A), a tight junction protein, is a key negative regulator of c

164 on and cellular distribution of claudin-1, a tight junction protein, is dysregulated in colon cancer

165 Claudin 3, a tight junction protein, is transiently incorporated into

166 e water channel protein, Aquaporin-3 and the tight junction protein isoform, ZO-1 alpha+.

167 strated that rat slit diaphragms contain the tight junction proteins JAM-A (junctional adhesion molec

168 wn as MARVELD2), which encodes a tricellular tight junction protein known as tricellulin, lead to non

169 Transmembrane tight junction proteins known as claudins are essential

170 ere used to examine gut barrier function and tight junction protein levels during 48-hour starvation

171 lso rapidly affected CPE cell morphology and tight junction protein levels.

172 f inflammatory cytokines, and alterations in tight junction protein localization and expression at th

173 FD4 flux as well as increased proportions of tight junction proteins located in the plasma membrane.

174 ion reverses the gut barrier dysfunction and tight junction protein losses due to a lack of enteral f

175 ribute to smaller infarction, changes in the tight junction proteins may lead to the greater edema fo

176 sa include the transcriptional regulation of tight junction proteins, metabolic regulation of barrier

177 ptake assay, quantitative RT-PCR analysis of tight junction proteins, myosin light chain kinase, and

178 to Tat diminished the expression of several tight junction proteins, namely, occludin, zonula occlud

179 expressed significant levels of Claudin-1, a tight junction protein needed for HCV infection of Huh-7

180 We provide evidence that the tight junction protein occludin (encoded by the OCLN gen

181 It has been previously determined that the tight junction protein occludin (OCLN) is essential for

182 l host factors, the tetraspanin CD81 and the tight junction protein occludin (OCLN), explain, at leas

183 vascular endothelial cells degraded both the tight junction protein occludin (p < 0.05) and the adher

184 TNF-alpha induced a relocalization of tight junction protein occludin and increased the latera

185 We provide evidence that the tight junction protein occludin contributes to the regul

186 dence for IL-17A-dependent regulation of the tight junction protein occludin during epithelial injury

187 hysiologic concentrations of progesterone on tight junction protein occludin expression and human gut

188 d Caco-2 cells in vitro through upregulating tight junction protein occludin expression.

189 modulator of METH-induced redistribution of tight junction protein occludin in brain endothelial cel

190 d that ischemia induced rapid degradation of tight junction protein occludin in cerebromicrovessels.

191 hough the C-terminal cytoplasmic tail of the tight junction protein occludin is heavily phosphorylate

192 Localization of the tight junction protein occludin was determined by immuno

193 Immunoblotting further showed that tight junction protein occludin was downregulated in ind

194 l lamina components, adhesion molecules, the tight junction protein occludin, and matrix metalloprote

195 re used to evaluate levels of cytokines, the tight junction protein occludin, and mucosal inflammatio

196 ription factor NF-kappaB and stabilizing the tight junction protein occludin.

197 hedding of heparan sulfate (DeltaHS) and the tight junction protein occludin.

198 rved levels of the cerebral endothelial cell tight junction protein occludin.

199 lular calcium and the internalization of the tight junction protein occludin.

200 domain has the same arch-shaped fold as the tight junction protein occludin.

201 not quality decreased the expression of the tight junction proteins occludin and claudin-1 in the sm

202 on of DSS than control mice, and loss of the tight junction proteins occludin and claudin-2 from inte

203 n astrocytic protein, and down-regulation of tight junction proteins Occludin and Claudin5, collectiv

204 trapping mutant of DEP-1 interacts with the tight junction proteins occludin and ZO-1 in a tyrosine

205 adherens junction protein beta-catenin, and tight junction proteins occludin and ZO-1 was unchanged,

206 sorganization and the mislocalization of the tight junction proteins occludin and ZO-1, suggesting th

207 xpression and localization of the intestinal tight junction proteins occludin and ZO-1.

208 tocin-induced diabetes inhibited the loss of tight junction proteins occludin and zona occludin- 1 (Z

209 lly, IGF2BP1 interacted with the mRNA of the tight-junction protein occludin (Ocln), stabilizing Ocln

210 s (Lgr5 and Bmi1), whereas the expression of tight junction proteins (occludin and claudin) in 13% CP

211 -insoluble membrane fractions confirmed that tight junction proteins (occludin, claudin-1 and zona oc

212 tion of the BBB manifested by the absence of tight junction proteins (occludin, claudin-5, ZO-1 and J

213 delayed apical junction localization of the tight junction proteins, occludin and ZO-1.

214 re, IL-25 restores the reduced expression of tight junction proteins, occludin, junction adhesion mol

215 ctively, these results indicate that loss of tight junction proteins occurs predominantly in the neoc

216 Tight junction proteins OCLN1 and TJP1were downregulated

217 cells and tissues may reflect differences in tight junction protein or lipid composition or post-tran

218 es not affect the progressive degradation of tight junction proteins or paracellular BBB leakage.

219 e further observed significant disruption of tight junction protein organization only in the ileum bu

220 lasma membrane, where it associates with the tight-junction proteins Pals1/PATJ and E-cadherin.

221 ition, Atg9 interacted with PALS1-associated tight junction protein (Patj), which associates with TSC

222 Z domain-containing protein Pals1-associated tight junction protein (PATJ), which has been described

223 c-Met transduction did not change tight junction protein patterns, suggesting unaltered ep

224 The claudin family of tight junction proteins plays an important role in regul

225 l adhesion molecule-A (JAM-A), an epithelial tight junction protein, plays an important role in regul

226 rical resistance and increased the amount of tight junction protein present in membrane fractions.

227 ericyte density, increased expression of BBB tight junction proteins, reduced brain infiltration of i

228 n cell polarity, as apical, basolateral, and tight junction proteins remain properly localized.

229 show that SPRY2 downregulates genes encoding tight junction proteins such as claudin-7 and occludin a

230 r permeability and reduces the expression of tight junction proteins such as occludin and zonula occl

231 ificant upregulation of luminal keratins and tight-junction proteins such as claudins.

232 stood but appear to involve dysregulation of tight-junction proteins such as claudins.

233 However, other tight junction proteins, such as claudin-1, ZO-1, and oc

234 onocytes resulted in decreased expression of tight junction proteins, such as junctional adhesion mol

235 nfiltration, and higher expression levels of tight junction proteins, such as zonula occludens-1 and

236 that heat stress may directly alter jejunal tight junction proteins suggesting an impaired intestina

237 Occludin is a transmembrane tight junction protein that contributes to diverse cellu

238 -mediated expression of claudin-2 (Cldn2), a tight junction protein that forms paracellular pores and

239 hesion molecule-A (JAM-A) is a transmembrane tight junction protein that has been shown to regulate b

240 Claudin-3 (CLDN3) is a tight junction protein that is overexpressed in 90% of o

241 Claudin-2 is a tight junction protein that mediates paracellular water

242 Junctional adhesion molecule-A (JAM-A) is a tight junction protein that serves as a receptor for reo

243 Here, we report marvelD3, a novel tight junction protein that, like occludin and tricellul

244 Epithelial barrier function is maintained by tight junction proteins that control paracellular fluid

245 Claudins are tight junction proteins that have been implicated in mai

246 rier function requires targeted insertion of tight junction proteins that have distinct selectively p

247 volves the formation of complexes containing tight junction proteins that include claudins and, somet

248 to evaluate the role of occludin, one of the tight junction proteins that regulate BBB functions in H

249 Claudins are tetraspan transmembrane tight-junction proteins that regulate epithelial barrier

250 barrier function by driving concentration of tight junction proteins through actin polymerization and

251 ta provide a link between the trafficking of tight junction proteins through endosomes and contact-in

252 roteins and altered membrane localization of tight junction proteins through Galpha12/Src signaling p

253 breakdown of type IV collagen and decreases tight junction protein (TJP) expression in a co-culture

254 Increased fluorescein staining and decreased tight junction protein Tjp1 expression demonstrated that

255 ludes the entire wild-type gene encoding the tight junction protein TJP2 (ZO-2).

256 y extravasation of Evans blue and changes in tight junction proteins (TJPs) as well as translocation

257 er (BBB)-disruption; decreased levels of the tight junction proteins (TJPs) claudin-5 and occludin; i

258 The contribution of tight junction proteins to barrier function is well esta

259 also shows good functional expression of key tight junction proteins, transporters, receptors and enz

260 The tight junction protein tricellulin marks these sites and

261 spheroid surface exhibits high expression of tight junction proteins, VEGF-dependent permeability, ef

262 time, and the expression of transporters and tight junction proteins was investigated by conventional

263 in-containing protein PATJ (Pals1-associated tight junction protein) was not per se crucial for the m

264 for epithelial-to-mesenchymal transition and tight junction proteins were assessed in exposed cells.

265 Cortical tight junction proteins were decreased in association wi

266 stinal epithelial permeability and levels of tight junction proteins were examined by permeable fluor

267 IL-17A and MMPs, and elevated the levels of tight junction proteins, which improved the BBB integrit

268 caine altered gut-barrier composition of the tight junction proteins while also impairing epithelial

269 repressed the translation of mRNAs encoding tight junction protein ZO-1 and adherens junction E-cadh

270 tic cobblestone morphology and expression of tight junction protein ZO-1 and pump protein Na+/K+ ATPa

271 strated delayed membrane localization of the tight junction protein ZO-1 consistent with a defect in

272 Moreover, the tight junction protein ZO-1 is mislocalized in the tal1-

273 Here, we demonstrate that the tight junction protein ZO-1 regulates tension acting on

274 regulator of migration through targeting the tight junction protein ZO-1.

275 positively correlated with the expression of tight junction protein ZO-1.

276 A contributed to BBB breakdown by disrupting tight junction protein ZO-1.

277 lial permeability and down-regulation of the tight junction proteins ZO-1 and claudin-1.

278 e III toxins altered the distribution of the tight junction proteins ZO-1 and occludin and were able

279 nges detected included redistribution of the tight junction proteins ZO-1 and occludin to lateral mem

280 but increased expression of the endothelial tight junction proteins ZO-1 and occludin, key mechanism

281 unocytochemistry confirmed expression of the tight junction proteins ZO-1 and occludin.

282 o reduce barrier function and influenced the tight junction proteins ZO-1 and occludin.

283 arrier in mice by reducing the levels of the tight junction proteins ZO-1, occludin and claudin-5 bet

284 t oxalate permeability, but knockdown of the tight-junction protein ZO-1 enhanced permeability to oxa

285 s manifested by EC apoptosis and loss of the tight-junction protein ZO-1.

286 utrophil infiltration, and a preservation of tight junction proteins (ZO-1 and occludin) composing th

287 microscopy using specific antibodies against tight junction proteins, ZO-1, and claudin-1 and by meas

288 er gene expression (e.g., GLUT-1), CD31, and tight junction protein ZO1 expression.

289 yosin heavy chain IIB, paxillin, Sec61 beta, tight junction protein ZO1, and Tom20.

290 DCK renal epithelial cells, silencing of the tight junction protein zona occludens 2 (ZO-2 KD) induce

291 thelial cell (hBMEC) monolayer integrity and tight junction protein zona occludens-1, while the resul

292 vessel basal lamina protein laminin, and the tight junction protein zona occludens-1.

293 ns revealed that heme primarily affected the tight junction proteins zona occludens-1, claudin-1, and

294 The expression of tight junction proteins zona occludens-1, occludin, clau

295 rylation of 30 different proteins, including tight junction protein zonula occludens 1 and aquaporin

296 y of the ileum and reduced expression of the tight junction proteins zonula occludens-1, occludin, an

297 BBB tight junction protein (zonula ocludens-1; ZO-1) localiz

298 ee Hb (HbG) on the expression of endothelial tight junction proteins (zonula occludens 1, claudin-5,

299 ecrease in the expression of the BBB-related tight junction protein, Zonula occludens-1 (ZO-1).

300 ecrease in the expression of the BRB-related tight junction protein, Zonula occludens-1 (ZO-1).