ライフサイエンスコーパス: tightly packed

1 vity, echo that PLFE liposomes are rigid and tightly packed.

2 extends from residue 36 to residue 98 and is tightly packed.

3 t the HNE-induced oligomers were compact and tightly packed.

4 that PLFE liposomes are generally rigid and tightly packed.

5 hereas mechanosensitive channel is the least tightly packed.

6 ike fold but its active-site helices are not tightly packed.

7 ipids were hydrolyzed and the protein became tightly packed.

8 t the deletions render the transporters less tightly packed.

9 (while keeping the topology) and thus can be tightly packed.

10 L-plastin bundles are much thinner and less tightly packed.

11 The tiles arrange into a tightly packed 2D array that is likely to resemble the p

12 step model where the A loop undocks from the tightly packed 50S ribosomal subunit, allowing RrmJ to g

13 +) ions through an inner cavity, whereas the tightly packed 6-stranded barrels need to assemble into

14 eocilia within each bundle contain a core of tightly packed actin filaments, whose length is dynamica

15 This patch is tightly packed against an underlying sandwich of chlorop

16 1248)SFYYS(1252) motif adopts a conformation tightly packed against the kinase C-lobe when Ser-1248 i

17 In addition, the unique double PXXP motif is tightly packed against the rest of the protein, renderin

18 ed step for HA-mediated fusion begins with a tightly packed aggregate of HAs whose fusion peptides ar

19 Internal CRUs were more tightly packed along z-lines than surface CRUs, containe

20 ver 800 predicted human proteins composed of tightly packed alpha-helical repeats (termed ANK, ARM, o

21 ates into a double beta-sheet structure with tightly packed alpha-helices decorating the exterior of

22 Apaf-1 CARD consists of six tightly packed amphipathic alpha-helices and is topologi

23 helical hairpin structure consisting of two tightly packed amphiphilic helices that rest on the memb

24 The two conformational extremes of a tightly packed and a loosely packed HAMP four-helix bund

25 r of cells in the clone, these clusters were tightly packed and confined to a single level of the VZ.

26 In the second stage, receptors are tightly packed and confined.

27 The N- and C-terminal helices are tightly packed and display several interhelical interact

28 The binding interface is tightly packed and dominated by hydrophobic amino acids.

29 within the temporal retina characterized by tightly packed and highly tiered cones emerges with subs

30 nsformation: the cells become enlarged, grow tightly packed and in multiple layers, and acquire the a

31 These 1.2 mum wide electrodes were tightly packed and positioned parallel in two opposite r

32 Hydrophobic cores are often viewed as tightly packed and rigid, but they do show some plastici

33 Helical membrane proteins are more tightly packed and the packing interactions are more div

34 alpha and beta components interact to form a tightly packed and well defined hydrophobic core.

35 oplast SR, the N-terminal "N" domain is more tightly packed, and a more extensive interaction surface

36 tailored to extended clusters, which may be tightly packed, and account for geometric exclusion effe

37 The alpha1/beta2/beta3 domain appears to be tightly packed, and the C terminus appears to behave as

38 pe IRF-3 showed that these three domains are tightly packed, and therefore, the dimer of IRF-3, which

39 erminal helices and the beta-sheets, is more tightly packed, and this might be responsible for its in

40 h thermostability, and adopt a very regular, tightly packed ankyrin repeat fold.

41 th a unique sequence and topology, forming a tightly packed anti-parallel dimer.

42 cation mechanism in the three homologous and tightly packed antiporter-like subunits L, M, and N of t

43 minent/abundant nucleoli and a colony with a tightly packed appearance and a well-defined edge.

44 The tightly packed architecture of calcium-free gelsolin, se

45 The duplexes form helical columns and are tightly packed around the 31-screw axis.

46 t size (DOI encoding permits detectors to be tightly packed around the subject and minimizes number o

47 s thousands of receptor subunits that form a tightly packed array at one pole.

48 nteract with the luminal environment using a tightly packed array of microvilli known as the brush bo

49 spatial vision requires that cones within a tightly packed array signal light to postsynaptic bipola

50 hrocytes and to compress erythrocytes into a tightly packed array.

51 Polarized epithelial cells create tightly packed arrays of microvilli in their apical memb

52 Globular proteins typically fold into tightly packed arrays of regular secondary structures.

53 (3 nanometers in diameter), where they form tightly packed arrays.

54 To relieve congestion among the 10 tightly packed aryl substituents in the product, the cen

55 le as those with cholesterol although not as tightly packed as judged by fluorescence anisotropy.

56 Skin HA forms tightly packed assemblies that have spring-like mechanic

57 ta suggest that PLFE liposomes are rigid and tightly packed at low temperatures, but they begin to po

58 erein each receptor-binding domain is either tightly packed at the membrane-distal apex or rotated in

59 g that the hormone-receptor interface is not tightly packed at this site.

60 oenzyme, suggests that inactive CaMKII forms tightly packed autoinhibited assemblies that convert upo

61 n the human body is the biofilm state, where tightly packed bacterial, archaeal, and fungal cells mus

62 ures indicate that the cores are composed of tightly packed beta-sheets possibly resembling 'steric z

63 1)DSVISLS(107) and (147)GVIGIAQ(153), reveal tightly packed beta-sheets with steric zipper interfaces

64 Once the tightly packed betaLG is disrupted, hydrophobic residues

65 arkable for the high density of mitochondria tightly packed between sarcomeres.

66 ovilli are length-matched and assembled into tightly packed "brush borders," which are organized by ~

67 protein that organizes actin filaments into tightly packed bundles believed to mediate the formation

68 BRTs revealed that these tangles are made of tightly packed bundles of long filaments with diameter a

69 nerve axons are unmyelinated and arranged in tightly packed bundles, features that may enhance ephapt

70 lasmic domains and extruded domain were less tightly packed but still retained secondary structure.

71 Both viruses have a single tightly packed capsid layer with 180 subunits assembled

72 Here, a method is described to prepare tightly packed carboxyl-terminated alkyl self-assembled

73 The results suggest that tightly packed caveolae lipids form a membrane platform

74 The preelectroporation TMP induced in tightly packed cells is analyzed for two sets of pulse p

75 ling proteins to traverse tissues containing tightly packed cells is of fundamental importance for ce

76 ter, and more homogeneously raise the TMP of tightly packed cells to a simulated electroporation thre

77 extracellular matrix fiber networks, between tightly packed cells, and between blood vessels or nerve

78 during animal development, through or around tightly packed cells, remains an incompletely resolved m

79 nanorods (GNRs) is often problematic due to tightly packed cetyltrimethylammoniumbromide (CTAB) bila

80 Lipid rafts are tightly packed, cholesterol- and sphingolipid-enriched m

81 in/RNA molar ratios show that ORF1p can form tightly packed clusters on RNA, with binding occurring a

82 rs Fos and Jun, which assemble as a soluble, tightly packed coiled coil structure.

83 ndent switch, would only express proteins in tightly packed colonies within tumors.

84 Tightly packed complexes of nucleocapsid protein and gen

85 ranules more severely than 600 MPa; however, tightly-packed complexes of globular starch granules-pro

86 denser and contained a higher proportion of tightly packed compressed polyhedral erythrocytes than t

87 tive biases the population strongly toward a tightly packed configuration that favors the network of

88 ampling the very large number of alternative tightly packed conformations, and the inaccuracies in cu

89 substituted K13-W106 residues to organize a tightly packed core and novel surfaces that may bind add

90 ormation with conserved residues forming the tightly packed core and polar residues lining the surfac

91 These results demonstrate that the tightly packed core of dihydrofolate reductase is acquir

92 t in which the a2, b1, and b2 domains form a tightly packed core that is only loosely connected to th

93 hat C-terminal residues Gly-29-Val-40 form a tightly packed core with intermolecular distances in a n

94 ediates have significant globularity (i.e. a tightly packed core), whereas the less structured interm

95 ced secondary structure and no evidence of a tightly packed core, but light scattering and fluorescen

96 tofilaments adopt beta-helix-like folds with tightly packed cores, resembling the cores of full-lengt

97 Furthermore, the presence of tightly packed DHA molecules tends to weaken the interhe

98 ) structure of human TMEM120A, which forms a tightly packed dimer with extensive interactions mediate

99 ructures have previously shown an identical, tightly packed dimer.

100 is composed of 11 protomers organized into a tightly packed disc with a flat membrane-embedded surfac

101 ceptor outer segment filled with hundreds of tightly packed "disc" membranes.

102 esidues 29-113 of the native sequence form a tightly packed domain with two alpha-helices on one side

103 But for the tightly packed double framework, geometric models predic

104 ation number (T) equal to 16-encapsidating a tightly packed double-stranded DNA (dsDNA) genome(1-3).

105 nfines of a protein capsid to transcribe the tightly packed dsRNA genome segments.

106 the hydrophobic core becomes desolvated and tightly packed during protein folding.

107 tion from largely unstructured monomers to a tightly packed, energetically favored ternary complex co

108 Our results indicate that a tightly packed environment made up of DNA, protein and s

109 eplacements might show opposite effects in a tightly packed environment, compared with a region lacki

110 The structure reveals two tightly packed epidermal growth factor-like domains orie

111 ike conditions by tracking single virions in tightly packed epithelial cells.

112 tures are common formations of hypertrophied tightly packed ER membranes devoted to specific biosynth

113 ey both form clots composed of thinner, more tightly packed fibers than their respective control rabb

114 clots that are composed of abnormally thin, tightly packed fibers with increased resistance to fibri

115 reased, consistent with a well-ordered, more tightly packed filament structure.

116 Heterochromatin is a tightly packed form of DNA involved in gene silencing, c

117 Heterochromatin, a tightly packed form of DNA, has been documented to suppr

118 stabilized by homotypic interactions between tightly packed fragments antigen binding (Fabs), many of

119 beta fold and shows that AcpS assembles as a tightly packed functional trimer, with a non-crystallogr

120 nd consistent electron density, suggesting a tightly packed Gag lattice, and Spumavirus-like particle

121 e to the ability of GlcCer to segregate into tightly packed gel domains.

122 estions arise about the organization of this tightly-packed gene region and about the evolution and f

123 ages arising from regulatory conflicts among tightly packed genes.

124 the hypothesis that the energy stored in the tightly packed genome within the capsid leads to its for

125 enic nucleotides although the other group is tightly packed, having no noncoding nucleotides, leading

126 the three hCS genes which co-assemble into a tightly packed 'hCS chromatin hub'.

127 tes that calbindin D(9k) has a core of three tightly packed helices (A, B, and D), with a dynamic fou

128 It consists of six tightly packed helices arranged in a topology homologous

129 raging the negative curvature induced by two tightly packed helices on membranes.

130 s well as the organization of chromatin into tightly packed heterochromatin and the loosely packed ge

131 o globular domains, 627 and NLS, that form a tightly packed heterodimer.

132 Fascins bundle actin filaments into large, tightly packed hexagonal arrays that support diverse cel

133 Tightly packed hexagonal bundles with controllable diame

134 y, MACANC proteins organized on membranes in tightly packed hexameric rings.

135 ace-exposed 'W56 loop' of PspF, which form a tightly packed hydrophobic cluster, the 'YLW' patch.

136 osely adjacent to the A1-A2 interface in the tightly packed hydrophobic core ((SER)289(LEU)) have the

137 Development of a tightly packed hydrophobic core drives the folding of wa

138 attributed to a number of factors, such as a tightly packed hydrophobic core, clusters of isoleucine

139 o maximize favorable interactions, forming a tightly packed hydrophobic core, exposing hydrophilic gr

140 e (HP67) reveals two subdomains that share a tightly packed hydrophobic core.

141 than aliphatic-aromatic interactions in the tightly packed hydrophobic cores of proteins.

142 examer is formed from two trimers, each with tightly packed hydrophobic cores.

143 FP1.4 are responsible for the formation of a tightly packed hydrophobic hub around the biliverdin D r

144 ertwined with screw symmetry and linked by a tightly packed hydrophobic interface.

145 on the ability of saturated lipids to form a tightly packed (i.e., tight in the sense that the lipids

146 Tightly packed ILV-dominated hydrophobic clusters could

147 unoreactivity spanning the layer composed of tightly packed immature cell bodies, i.e., the cortical

148 ral proteins on cellular membranes to form a tightly packed immature virion.

149 he nanobody (15 kDa) enable its oriented and tightly packed immobilization on magnetic beads, providi

150 ix strands and one of seven strands that are tightly packed in a beta-barrel or beta-sandwich arrange

151 bending of most cells that are large and not tightly packed in a cell layer.

152 nd His(281), whereas the naphthalene ring is tightly packed in a hydrophobic subpocket formed by the

153 The interior atoms of the protein are tightly packed in each individual conformation that cont

154 The double-stranded DNA is tightly packed in the capsid as a left-handed superhelix

155 ture shows that the four disulfide bonds are tightly packed in the center of the domain, replacing th

156 ore, it is present only when the helices are tightly packed in the closed conformation.

157 erminal region of the alpha subunit was less tightly packed in the folding intermediate.

158 xture of sea ice, icebergs, and snow) may be tightly packed in the long, narrow fjords that front man

159 cation--but not because rhodopsins were more tightly packed in the membrane.

160 omatase clusters were also more abundant and tightly packed in the NCM of males as compared to female

161 indicate that the C1 domains of RDdelta are tightly packed in the plane of the membrane in the two-d

162 We infer that the M2 segments are tightly packed in this region.

163 d differentiating between concepts that are 'tightly packed' in semantic space, such as living things

164 thin all of the thrombi and emboli were very tightly packed, in contrast to clots formed in vitro.

165 rms of gene regulation, pioneer factors open tightly packed, inaccessible chromatin sites, enabling t

166 contacts between apolar groups, i.e. a more tightly packed interface forms than in NSS complexes.

167 P67 is made up of two subdomains that form a tightly packed interface.

168 7 is made up of two subdomains, which form a tightly packed interface.

169 e sliding over a continuously maintained and tightly packed interface.

170 The pairing occurs via tightly packed interfaces, reminiscent of recently repor

171 We show that the most abundant tightly packed interfacial residues in membrane proteins

172 Waals interactions of peptide groups in the tightly packed interior of folded protein are more favor

173 er Waals interactions of polar groups in the tightly packed interior of folded proteins are more favo

174 ed motions, whereas most form the centers of tightly packed internal regions.

175 EM showed that hundreds of viral capsids are tightly packed into several layers of fibrous PML.

176 , with or without JSRV, show agglomerates of tightly packed intracellular particles most abundant in

177 low-contrast overlapping objects that may be tightly packed is a major bottleneck in standard deep le

178 ll bodies >10 deep have thin, elongated, and tightly packed IS/OS.

179 rticles and flat electrodes, or organised as tightly packed islands of hundreds and thousands of mole

180 The MB pedunculus contained ca. 50,000 tightly packed KC axons, showing conspicuous en passant

181 e the three dimensional spatial structure of tightly packed krill schools.

182 acterize molecular properties of proteins in tightly packed lattices.

183 and myosin II filaments were organized into tightly packed linear arrays oriented along the axis of

184 , which is relieved by CL remodeling to form tightly packed lipid-protein complexes.

185 two types of liquid-ordered phases, one with tightly packed lipids and one in which the apparent spac

186 ea, with no dioptric apparatus, apposed by a tightly packed, massive array of photosensitive membrane

187 The mice first shred the tightly packed material, then arrange it into a nest.

188 lecules due to their capability to form more tightly packed membranes compared to typical monopolar l

189 ls that can be explained by the existence of tightly packed micro-domains moving in a more fluid back

190 to obvious laminae, anatomical evidence for tightly packed microcolumnar ensembles containing approx

191 sh border provides an elaborate example with tightly packed microvilli that function in nutrient abso

192 isk of light scattering or absorption, these tightly packed mitochondria "focus" light for entry into

193 lly-realistic cellular landscape composed of tightly-packed mitochondria and myofibrils.

194 stidine rich domain (CHRD) composed of three tightly packed modules named M1, M2, and M3.

195 e core of the GFP, a particularly stable and tightly packed molecule.

196 from HPLC columns containing solid phases of tightly packed monolayers of phosphocholine amphiphiles

197 ptability to adsorbing arbitrary proteins in tightly packed monolayers while retaining functionality.

198 ays after cell implantation and consisted of tightly packed monotypic cells that were CD48+, CD47+ an

199 tion based 3D reconstruction framework for a tightly packed multilayer tissue with extreme z-sparsity

200 The results show that the tightly packed native structure of cytochrome c is disru

201 onic lipid membranes is known to disrupt the tightly packed native structure of the protein.

202 10% of the total telomeric DNA, consists of tightly packed nucleosomes clustered at the inner border

203 rimeric nucleic acid chaperone that can form tightly packed oligomers on nucleic acids.

204 es with left-handed crossing angles are more tightly packed on average than helices with right-handed

205 In the inward-facing conformer, LacY is tightly packed on the periplasmic side, and Trp residues

206 s, up to thousands of individual florets are tightly packed onto a capitulum disk.

207 and fungal sterols promote the formation of tightly packed, ordered lipid domains by lipids with sat

208 ith the hyperaggregation of Abeta leading to tightly packed, ordered plaques, suggesting that one asp

209 ms of starch, cellulose, and chitin can have tightly packed organizations of polymer chains with low

210 Btbd7 knockout results in more tightly packed outer bud cells, which display stronger E

211 sion of Pcdh genes allows for convergence of tightly packed, overlapping olfactory sensory neuron axo

212 structures are, however, typically formed of tightly packed parallel helices.

213 ing proteins have been described: HAMP(A), a tightly packed, parallel, four-helix bundle; and HAMP(B)

214 mbly of five Ca(2+)-S100A4/TFP dimers into a tightly packed pentameric ring.

215 es the crystal conformation though with more tightly packed peripheral helices.

216 reactivity of single-Cys replacements in the tightly packed periplasmic domain of wild-type LacY, whi

217 opening, we replaced paired residues on the tightly packed periplasmic side of LacY with Cys, and th

218 ation with an open cytoplasmic pathway and a tightly packed periplasmic side, which makes the binding

219 smic cavity closes, and a cleft opens on the tightly packed periplasmic side.

220 s also the dominant source of friction: more tightly packed phages initiate ejection earlier, but wit

221 to Le(x) disrupted the monolayer and caused tightly packed polygonal cells to round up.

222 orientation of the long axes of aligned and tightly packed polysaccharide fibers in compressed subst

223 Gb3-R favorably induces large and tightly packed protein clusters, while a lower protein d

224 ime the lipid is occupying the voids between tightly packed protein molecules.

225 We found that most of the tightly packed protein regions did not tolerate structur

226 Fusion of effector proteins to tightly packed proteins-such as GFP, ubiquitin, or dihyd

227 (CO...SN) interactions in generating rigid, tightly packed radical pi-stacks, including the structur

228 tructure of the D3 dopamine receptor shows a tightly packed region of aromatic residues on helices 5

229 th two adjacent collagen monomers, forming a tightly packed region.

230 low dielectric of the membrane or located in tightly packed regions of the structure react poorly.

231 a frzG methylesterase mutant forms numerous, tightly packed ripples.

232 er surface of its protein shell, embedded in tightly packed RNA.

233 ), and bands often contained clusters of >70 tightly packed RNAPs (possibly engaged on one long ribos

234 toside, most of the particles are present in tightly packed rows of dimers.

235 gh a non-canonical pathway that involves the tightly packed S4-S5-S6 interface.

236 Ice melange, tightly packed sea ice and icebergs, has been hypothesiz

237 The tightly packed selectivity filter contains multiple ion-

238 small organic molecules, in contrast to the tightly packed self-assembled monolayers of alkanethiols

239 specific volume of 0.7 cm3 g(-1), forming a tightly packed shell with an outer radius of 4.04+/-0.15

240 designed systems(9-13) in that they possess tightly packed shells devoid of large apertures.

241 regular microscopic structure consisting of tightly packed, short, transversal clonar columns.

242 ing and H(+) translocation at the apex and a tightly packed side facing the periplasm.

243 amination under low-energy environments with tightly packed small sediment particles compared with hi

244 nar (up to 12 cells thick), nonkeratinizing, tightly packed small squamous epithelial cells that surm

245 of the major structural protein, Gag, into a tightly packed, spherical particle that buds from the me

246 actor C (RFC)] revealed a different and more tightly packed spiral organization of the ATPase domains

247 to cell and genome size minimization include tightly packed spirals inferred to be DNA, few densely p

248 For lutein, the aggregates consist of tightly packed stacks of individual carotenoid molecules

249 e, ranging from zero to values approaching a tightly packed state.

250 e cytoplasmic protein interactions mediate a tightly packed state.

251 ly display two peculiar structural motifs: a tightly packed steric zipper interface and a large numbe

252 oebae chemotax toward aggregation centers in tightly packed streams in which cells are organized in h

253 We conclude that these residues form a tightly packed structural microdomain that connects heli

254 reveals that the ZU5-ZU5-UPA domains form a tightly packed structural supramodule, whereas DD is fre

255 evious study of GFP crystal structure that a tightly packed structure exists in the protein.

256 n and accessible major groove to a much more tightly packed structure that is folded around basic sid

257 tated as RING0) and RBR domains, revealing a tightly packed structure with unanticipated domain inter

258 ypsin and thermolysin resistance indicated a tightly packed structure.

259 oiled-coils (CCs) but instead forms a rigid, tightly packed structure.

260 thermal denaturation curve consistent with a tightly packed structure.

261 ayers switch from a loosely packed to a more tightly packed structure.

262 e of the Abeta42 sequence, suggesting a more tightly packed structure.

263 roximately 124-227 more readily adopt stable tightly packed structures than the N-terminal residues a

264 illivirus H-stalk domain is composed of four tightly-packed subunits.

265 Clusters of tightly packed synaptic vesicles (SVs) are a defining fe

266 Simulations suggest that migration creates tightly packed systems with planets whose orbital period

267 mammals, taste buds typically contain 50-100 tightly packed taste-receptor cells (TRCs), representing

268 non-)native secondary structure and lack the tightly packed tertiary structure of natively folded glo

269 ls within translucent colonies appeared more tightly packed than cells in opaque colonies.

270 hat membrane helices are not on average more tightly packed than helices in soluble proteins; they ar

271 of double-stranded DNA are, on average, more tightly packed than in related small molecules in the CS

272 s imply that proteases are, as a group, more tightly packed than other proteins.

273 C transmembrane domain is significantly more tightly packed than the corresponding region of the Torp

274 These proteins are so tightly packed that their excluded area interactions can

275 shell and predicts that a failure to form a tightly packed thrombus core will limit thrombin accumul

276 ng of P5abc, the catalytic core becomes more tightly packed through indirect effects of the tertiary

277 eir contact with neighbouring cells in these tightly packed tissues is poorly understood.

278 (alanine to phenylalanine) in the predicted, tightly packed TM domain dimer interface.

279 termine a conformation either in or near the tightly packed TM region and this conformation and/or it

280 ls a C1r2s2 with its serine protease domains tightly packed together in the center of C1 and an intri

281 In the closed state, four tightly packed transmembrane helices define a narrow cha

282 It has a tightly packed trimeric structure with an eight-stranded

283 s are resistant to most proteases due to the tightly packed triple-helical structure, but are readily

284 f the archaeal rhodopsin family of proteins, tightly packed triplet interactions can be achieved with

285 e stabilize the complex primarily by forming tightly packed van der Waals interactions with one anoth

286 n immature virions where capsid hexamers are tightly packed, where nucleocapsid domains align beneath

287 eriorhodopsin and halorhodopsin are the most tightly packed, whereas mechanosensitive channel is the

288 double-stranded RNA genomes selectively and tightly packed with a conserved number of transcription

289 tivity in a mammalian nervous system that is tightly packed with billions of cells, we developed a ne

290 Ordered domains are tightly packed with cholesterol, sphingomyelin, and satu

291 stable in the molten globule state, and are tightly packed with each other in this state, similar to

292 m molten globule state, and are likely to be tightly packed with each other in this state.

293 Because bacterial chromosomes are tightly packed with genes and were traditionally viewed

294 aea typically possess small genomes that are tightly packed with protein-coding genes.

295 he method used a column with 2mm ID that was tightly packed with silica gel followed by alumina.

296 micelle-like structure in which the label is tightly packed with the hydrophobic bases.

297 The ASRT tetramer is tightly packed, with large interfaces where the well-str

298 The neurons were tightly packed within a perineural sheath, and the cell

299 l six transmembrane helices of CmTMEM175 are tightly packed within each subunit without undergoing do

300 The 11-cis retinal chromophore is tightly packed within the interior of the visual recepto