ライフサイエンスコーパス: time

1 as been an improvement in their quality over time.

2 re species' ranges are static or change over time.

3 years and increased with species' generation time.

4 ear, to reveal its morphology for the first time.

5 nd the risk of malignant transformation over time.

6 ICC below 0.4 indicating poor stability over time.

7 ed a selective and progressive increase over time.

8 y and individual differences in outcome over time.

9 etal transitions are presented for the first time.

10 s, or decreasing intraburst frequencies with time.

11 arrier function and metabolic stability over time.

12 calcium levels that fade over developmental time.

13 r cherry vinegar were revealed for the first time.

14 e presented closer to the eye movement onset time.

15 synthesized and characterized for the first time.

16 ular interactions governing ligand residence time.

17 community structure as a smooth function of time.

18 d populations of cells to be studied in real time.

19 t pyrolaside B was synthesized for the first time.

20 he hydrogels can be re-programmed time after time.

21 ed features of their regulation in space and time.

22 finger was instructed to produce force at a time.

23 ystallization at -30 degrees C for the first time.

24 entification without increasing the analysis time.

25 cytophaga) in their relative abundances over time.

26 lytic conditions were compared for the first time.

27 -CoV-2 viruses were diverse and changed over time.

28 s in populations and their interactions over time.

29 the transients at longer indirect evolution times.

30 to revolutionize spectroscopy, metrology and timing.

31 treatments were involved i.e. three soaking times (0, 15, and 30 min), three temperatures (20, 25, a

32 was observed within an individual child over time (2% to 42% of zOTUs in saliva; 2.5% to 38% in denta

33 he cohort included short median PSA doubling time (2.3 mo) and extensive prior treatment, including p

34 he lack of a formal description until recent times (2006) and its strong morphological resemblance wi

35 This study provides for the first time a novel insight into the molecular basis of sinonas

36 In modeling simulations, tumor cell doubling time, administered antibody, antibody specific-activity,

37 ge, 6-44 d) and postoperative (18)F-FET PET (time after surgery: median, 14 d; range, 5-28 d) were in

38 of waste, the hydrogels can be re-programmed time after time.

39 open-label extension (part B), during which time all participants received clazakizumab.

40 ion time and five clinician capillary refill time, alternating second and third digits.

41 The interaction between ischemic time and alteplase dose was statistically significant (p

42 ents an efficient strategy which can lead to time and cost saving post-translational, covalent conjug

43 ents, including five full finger reperfusion time and five clinician capillary refill time, alternati

44 gold standard' for precision measurements of time and frequency.

45 hods, which provide information at different time and length scales, are used to gain fundamental und

46 nd other existing materials lack in response time and stability at elevated temperatures.

47 s challenged by the pathogen's slow doubling time and the lack of methods to quickly quantify the pat

48 ontingently within and against a backdrop of time and timescales.

49 to what extent metabolic health changes over time and whether such transition affects risks of subtyp

50 construct the index in less than 36% of the time and with 39% less space and can answer small-batch

51 lized substrates required longer irradiation times and resulted in lower surface coverage at the same

52 sumption on the eastern Eurasian steppe over time, and an expansion of isotopic niche widths, indicat

53 ts a high proton conductivity, fast response time, and extremely large on/off ratio upon visible-ligh

54 rological failure is relatively rare at this time, and the recommendations for switching therapies fo

55 contact after birth, to have it for a longer time, and to breastfeed immediately after birth and at h

56 characteristics (delivery platform, delivery timing, and health system objective) and did one-way and

57 dom fashion with respect to their direction, timing, and magnitude.

58 n scattering from water depends on the delay-time as expected.

59 between tones became increasingly stable in time as the information coded by those patterns transiti

60 ifferences between genotypes and pollination time as well, which demonstrated high performance of the

61 Globally, soils store two to three times as much carbon as currently resides in the atmosph

62 ns of detergents or lipoproteins, incubation time, as well as the order of mixing reaction components

63 , describe changes in genetic diversity over time, assess the relationship between contemporary and h

64 mparison to a single mouse bed, the cost and time associated with each scan were substantially reduce

65 cess of fusion, we incubate HA for different times at pH 5.0 and directly image structural changes us

66 t with accompanying numerical simulations, a time-bandwidth product (TBP) exceeding the 'fundamental'

67 curacy to nCV, but cnCV has much shorter run times because it does not construct classifiers in the i

68 , 34 recurrent tumors) who had preoperative (time before surgery: median, 23 d; range, 6-44 d) and po

69 At 12 times before, eight times during, and four times followi

70 level, PSA doubling time, PSA velocity, and time between initial treatment and PET imaging was evalu

71 These synaptic dynamics are timed by Rac1, with decreased and increased Rac1 activit

72 Here, we report a time-calibrated phylogenomic analysis based on genotypin

73 lly, nePVAC develops signs of exudation over time, causing metamorphopsia and visual decline and ther

74 en considered relatively more stable through time compared to the conditions on land.

75 provides a tractable solution to reduce the time complexity and physical layer costs of quantum comp

76 y proposed methods are often inefficient and time consuming and consequently, only able to produce an

77 hods to determine disease related miRNAs are time consuming and costly.

78 These processes are time consuming and they do not consider novel microbial

79 However, such experiments can be time-consuming and costly, which has led to the developm

80 assays which require expensive reagents, is time-consuming and more often is only indicative and can

81 reports had low channel counts and required time-consuming manual assembly.

82 would be desirable as an alternative to the time-consuming purification of LCs from human skin.

83 l neural networks are notoriously power- and time-consuming when implemented on conventional von Neum

84 l assays that retain the challenges of being time-consuming, poorly sensitive and expensive.

85 The real-time control of the ultrasound dose delivered through th

86 A literature survey indicated signaling time course data usually conform to one of four curve sh

87 l tested modeling approaches when metabolite time course data were missing, but found these effects t

88 The time course of these signals suggest that this misaligne

89 rubecestat on brain volume by evaluating the time course of volumetric MRI changes for a variety of b

90 nown about the circuits that integrate these time cues to drive a coherent circadian output(1-3).

91 remained on their original regimen (CsA CE 4 times daily [QID, high-dose] or CsA CE twice daily [BID,

92 terface that joins a direct analysis in real time (DART) probe, solid-phase microextraction (SPME) fi

93 Conversion over time data is obtained by cycling a discrete reaction slu

94 ELF was evaluated as a time dependent variable by generating time-dependent Cox

95 d as a time dependent variable by generating time-dependent Cox models; HRs at an ELF threshold of 10

96 Quantum mechanical time-dependent density functional theory (TDDFT) calcula

97 port) at that same time (unexposed), using a time-dependent propensity score.

98 and determined the role of GSK3beta in spike timing-dependent long-term potentiation (tLTP) in the ch

99 While this facilitates real-time detection of statistically significant Rt changes,

100 proach could ultimately facilitate near-real-time diagnosis and therapy.

101 logists, as a complementary device, for real-time diagnosis of suspicious margins of dissected tumors

102 time-of-day effect is large, and exceeds the time difference between gold and silver medal in 40%, si

103 Here, for the first time, differential pulse voltammetry (DPV) has been succ

104 feedback loops, illustrate that the waiting time distributions of each molecule are a signature of t

105 lly twisted in the space-frequency and space-time domains.

106 maximizing the capabilities of existing real-time dPCR instruments and chemistries, by extracting mor

107 t correctly identified TB status at distinct times during treatment.

108 At 12 times before, eight times during, and four times following the cessation of

109 olevo lower bound is used to derive a proper time-energy/mass uncertainty relation.

110 g an increase in its oxidation by increasing times, especially with chlorpyrifos.

111 that exhibit closely-related behaviors over time, even if the timing is not perfectly synchronized.

112 MD data were subsequently used to calculate time evolution of the relevant spin density matrix and t

113 can answer small-batch queries at least five times faster.

114 2 times before, eight times during, and four times following the cessation of discharging hypersaline

115 The optimal SPECT scanning time for (177)Lu-DOTATATE was approximately 72 h p.i., w

116 lls, and the bioluminescence tracked in real time for accurate quantification off chip.

117 sted twice as long as the predicted survival time for selectively neutral nuclear alleles.

118 ) and decreased in frequency with increasing time from implant (from 9.7% of patients at <5 years to

119 The time from randomization to resolution of stromal keratit

120 Mean time from surgery to presentation was 51 days (range, 4-

121 in less severe autonomic dysreflexia, a real-time gauge of sympathetic hyperreflexia, for months post

122 tes predict conservation cost with up to 8.5 times greater accuracy than earlier proxies.

123 ise spontaneously at a rate approximately 25 times greater than DNA sequence changes and typically ha

124 ere is minimally invasive, and for the first time, greatly enhances our ability to measure neonate tu

125 1 ms and conduction block (CB) as conduction time >=12 ms.

126 isions to act emerge at particular points in time has been lacking.

127 how the need for reduced clinical turnaround times has influenced chemical instrumentation.

128 analyses, the odds of having A-HSIL were >6 times higher in women with anal hrHPV (adjusted odds rat

129 itive (>0.3 units) after resuscitation had 3-times higher risk compared to those who remained negativ

130 obal warming and temperature potentials) and time horizons (20 and 100 years).

131 g M. kansasii pathogenesis and for the first time identify extracellular cords in this species.

132 development index and the expected length of time in education for women and the three outcomes: sexu

133 The study aimed to explore, for the first time in Nepal, potential geographic and socioeconomic va

134 The decline over time in reported cough was statistically significant in

135 13) and time (P < 0.001) in Study 1 and with time in Study 2 (P < 0.001).

136 Here, we report for the first time in-depth single-cell RNA sequencing, combined with

137 exhibited increased N(2)O production, by 74 times in mineral soil and 2 times in organic soil.

138 roduction, by 74 times in mineral soil and 2 times in organic soil.

139 e infection in a latent phase, for the first time, in olive drupes, 16 hai, and in olive oils contain

140 C(4) photosynthesis evolved multiple times independently from ancestral C(3) photosynthesis i

141 , the integral of the PFA concentration over time (integral CT or ICT).

142 features, such as variations in duration or time-integrated activity.

143 re anti-CD20 administration and in different time intervals thereafter over a period of 24 mo.

144 s patient-selected cinematic content in real-time into therapeutic visual input, while objectively mo

145 he nonreciprocity is induced by breaking its time-invariance, we report, in full agreement with accom

146 eterization laboratory (cath lab) activation time is a newly available process measure for patients w

147 ely-related behaviors over time, even if the timing is not perfectly synchronized.

148 ets(14,15), optical frequency synthesis(16), time keeping(17) and other areas(10).

149 Using live time-lapse imaging of primary resected tumors, we discov

150 Time-lapse microscopy showed that HuR was required for t

151 loud sounds and reduced behavioral reaction time latencies to high-intensity sounds.

152 is a monosaccharide approximately a hundred times less abundant than glucose in human blood.

153 rrow temporal window, sample processing is a time-limiting step for research on the early life-histor

154 A one-time LTBI testing and treatment intervention among non-U

155 As with paper-loaded direct analysis in real time mass spectrometry (pDART-MS).

156 Extrapolation of instantaneous, "snapshot-in-time" measurements, for example, can miss temporal inter

157 he present study, we examined, for the first time, mechanisms of the long-range traffic of DAT in int

158 such as foraging orientation and navigation, time-memory for food sources, sleep, and learning/memory

159 ch lacks adjacent hydroxyl groups, and are 7 times more active than the active sites in Zn-DeAlBEA.

160 The active sites in Y-DeAlBEA are 70 times more active than the Y sites supported on silica,

161 nsertion into the graphene makes the EEVD 10 times more sensitive than traditional graphene field-eff

162 iven revised CO(2) limits and (for the first time) N(2) respiration limits for complex life.

163 trahigh mass resolution of Orbitrap for real-time, near-molecular characterization of OAs.

164 ere transplanted after a median preservation time of 18 h, with 100% 90-day survival.

165 During a median follow-up time of 62.5 months, 564 of the 3,478 participants progr

166 CD) was defined as interelectrode conduction time of 7 to 11 ms and conduction block (CB) as conducti

167 q (range, 132-410 MBq), with a median uptake time of 79.5 min (range, 60-153 min).

168 The time of a stochastic process first passing through a bou

169 a clearance and increased drug exposure over time of ALDC1 were observed compared to ALDC3 and MMAE p

170 on between measurements, as well as cost and time of analysis.

171 At the time of application, awardees were more likely to have e

172 early 6 year period, July 2007-April 2013, a time of both rapid ocean warming throughout the Gulf of

173 risk, and correlate with paternal age at the time of conception.

174 At time of extraction, measurements were taken with a custo

175 matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) with onl

176 ted for model for end-stage liver disease at time of hospital admission, serum levels of albumin and

177 the patient may no longer be present at the time of image interpretation, quality assurance is key d

178 glycogen or LBs to levels below those at the time of intervention.

179 r for lactate detection which had a response time of less than 10 s over the range of 0.05-1.8 mM.

180 Comorbid conditions at time of LTBI testing (e.g., HIV, diabetes, chronic kidne

181 al-enhanced imaging was not available at the time of recent presentation, so comparison was made with

182 as previously shown to prolong the residence time of rhDNase in the lungs of mice after pulmonary del

183 2) in each sample vial, from which Threshold Time of sensor signal was determined and then TVC values

184 At the time of study enrollment when a formal LVAD evaluation w

185 At the time of the primary efficacy analysis (ie, when all part

186 a sparse fossil record, particularly at the time of their extinction near the Cretaceous-Paleogene b

187 Lastly, contractions at different times of day resulted in differential changes of core cl

188 party participation is maintained throughout times of rapid change to adapt while supporting essentia

189 e that light regimes play in determining the timing of biological activity.

190 ient-reported outcomes to inform appropriate timing of face-to-face visits and enable improved applic

191 to test hypotheses related to the source and timing of introduction of invasive species.

192 Mating behaviour and the timing of reproduction can inhibit genetic exchange betw

193 n of SHR transcription modulate the division timing of two different specialized cell types in the ro

194 The time-of-day effect is large, and exceeds the time differ

195 Oxidation induction time (OIT) using differential scanning calorimetry showe

196 here in whole bacterial cells for the first time, opens the path for future investigations of the bi

197 was 18.9% (95% CI, 17.7%-20.2%), stable over time (P > .05 for both 2010-2016 and 2003-2009 vs 1996-2

198 trogen increased with dosage (P = 0.013) and time (P < 0.001) in Study 1 and with time in Study 2 (P

199 ter ratio (P = 3.6 x 10-4), the MTX infusion time (P = 1.5 x 10-3), FPGS mRNA expression (P = 2.1 x 1

200 lications and bleeding events decreased over time (P value for trend test <0.0001); however, there wa

201 control (i.e. increased Stop-signal reaction time; p = 0.031 and p = 0.053 respectively).

202 cluded peri-intubation complications, apneic time, PaO2 before and after intubation, PaCO2 after intu

203 med using a previously published duplex real-time PCR (capable of detecting E. histolytica and E. dis

204 stolytica and E. dispar), our tetraplex real-time PCR assay demonstrated levels of sensitivity and sp

205 e with those demonstrated by the duplex real-time PCR assay.

206 There was a quadratic fit between time per bite and bite mass (P = 0.006).

207 ere prepared and applied on the enamel three times per day once a week, for 4 weeks.

208 Consequently, therapists spent substantial time performing exercises that elicited little muscle ac

209 sidents of index households over a sustained time period could contribute to malaria elimination effo

210 Finally, we demonstrate a portable and real-time POC device to detect SARS-CoV-2 from VTM samples us

211 , MCP-1, and IL-6 levels changed at a single time point.

212 typically developed and validated for single time-point assessment, in highly controlled settings, an

213 At later time points following lysosomal injury, Gal3 controlled

214 AD participants, with comparable measurement time points in STAY participants.

215 with empirical impairment observed at later time points of white matter and clinical decline using b

216 alyse live body weight measured in different time points throughout the growth phases of 4469 Scottis

217 viability was analysed on-chip at different time points using fluorescence microscopy and Lactate de

218 d similar growth kinetics; however, at early time points, HVT-DeltavNr-13 showed 1.3- to 1.7-fold-low

219 infer a continuous distribution map between time points.

220 ent in tissue and blood samples from earlier time points.

221 Most people report feeling persistently 'time poor'-like they have too many things to do and not

222 ) within 180 days and 13.6% (120/881) at any time postoperatively.

223 campaigns can be analyzed to facilitate real-time process monitoring and control.

224 se Events, do not provide information on the time profile of these adverse events or reflect the cont

225 The measurements reveal time profiles of dissolved O(2) in each sample vial, fro

226 ancer Network stage, PSA level, PSA doubling time, PSA velocity, and time between initial treatment a

227 At the same time, quality of super-resolution imaging depends on hig

228 An estimation of the times required to form the loops of typical sizes seen i

229 t spectroscopic tools such as steady-state & time-resolved fluorescence spectroscopy, Circular Dichro

230 ts in brain parenchyma, allowed high-content time-resolved imaging of cell migration.

231 fer (around 90% efficiency), as evidenced by time-resolved spectroscopy.

232 Here, we establish that partial time reversal transforms the beam splitter linear coupli

233 (2D) topological band insulators with broken time-reversal symmetry.

234 transcriptional profile and DNA replication timing (RT) under mild replication stress in the context

235 visual search task while recording response times (RTs) and event-related potentials, focusing on th

236 fluence of parameters name as pH, extraction time, sample volume and amount of sorbent were optimized

237 CaRe is a time-saving procedure that can purify lectins even from

238 clamshell-like conformational changes on the time scale of seconds, examining the relationship betwee

239 l platform to achieve very rapid (picosecond time scale) and highly efficient energy transfer (around

240 emerge mostly due to the different transport time scales at different regions of the flow network, wh

241 ings involve different inheritance patterns, time scales, chromatin structures, and environmental exp

242 lications that can bridge diverse length and time scales.

243 heir interspike intervals (ISIs) reflect DAP time-scales.

244 matrix based on partial correlations between time series in the different regions in each subject to

245 eighted Correlation (LPWC) to group pairs of time series that exhibit closely-related behaviors over

246 ys, and data were analyzed by an interrupted time series.

247 We modelled CCF50 as a time-series random walk function of educational attainme

248 ously addressed this challenge by developing time-shifted mean-segmented Q (tsMSQ) analysis and appli

249 m) MukBEF axial core, whose length is ~1,100 times shorter than the chromosomal DNA.

250 y noncompliant, reduced preincision infusion time, significantly predicted SSI (<24.6 min infusion, A

251 The association varied according to time since diagnosis with an adjusted IRR for 1 to 3 mon

252 significantly associated with viral load was time since onset of symptoms.

253 The effects of age at BCG and time since vaccination were also explored.

254 development of clinical AD; especially, the time-specific associations were notable: t-tau 8 to 16 y

255 lts on 12 disease-gene associations and on a time-stamped benchmark containing 42 newly discovered as

256 ronmental volatility described by continuous-time stochastic processes.

257 lant used in plasma separator tubes, storage-time, storage-temperature, and repeated freeze-thaw cycl

258 We conducted a time-stratified case-crossover analysis with conditional

259 eficits in a prospective cohort of 132 first-time stroke patients studied at 2 weeks post-injury (mea

260 Finally, applying space-for-time substitution, a strong antagonistic (i.e. dampening

261 mount of MeIQ formed increased with reaction time, temperature, and oxygen content in the reaction at

262 This demonstrates for the first time that PA influences the biological activity of chito

263 e low-effective-diffusion constants leads to times that are unphysically large.

264 Selenate influx in cadt1 was 2.4 times that of the wild-type.

265 We demonstrate for the first time the SFC-MS separation of a mixture of polypeptides

266 esidence coils, with analysis performed each time the solution is passed between the two.

267 mapping to substantially reduce measurement time thereby enabling the acquisition of reasonably larg

268 scular lumen express MC markers and at later times they co-express MC and EC-specific proteins and ma

269 l width at half maximum of 29 nm, and a T80 (time to 80% of the initial luminance) of > 60 h at an in

270 alysis of BBxgenotype interaction predicting time to all-cause mortality, adjusted for Meta-Analysis

271 ry for more than one hundred years and it is time to bring her back.

272 The primary outcome was time to death or symptomatic stroke confirmed by imaging

273 d surgical wards has the potential to reduce time to detect deteriorating patients.

274 textured implants (1 in 871), with a median time to diagnosis of 10.3 years (range, 6.4-15.5 yrs).

275 ey have too many things to do and not enough time to do them.

276 of the prespecified renal composite outcome (time to first occurrence of either: >=50% reduction in e

277 Here, we compare fixed-time to on-the-fly decisions, based on comparing the lik

278 No sex difference in time to task failure was observed in either trial.

279 Time to task failure was significantly shorter after sle

280 These findings reveal for the first time, to our knowledge, the dynamic behavior whereby Tfh

281 from ulcerative colitis (UC), in which first-time treatment with vedolizumab was initiated.

282 When adopted nationally outside the TIME trial, MIE was associated with an increase in total

283 cations for the design of new long-residence-time TSPO ligands.

284 risk of intra-arrest transport) at that same time (unexposed), using a time-dependent propensity scor

285 For instance, recent studies of flowering time variation have reconstructed how, when, and where p

286 effective reproduction number, Rt, is a key time-varying prognostic for the growth rate of any infec

287 state trajectories which may be complex and time-varying.

288 extracorporeal membrane oxygenation support time was 96 hours (interquartile range, 26-181 hr).

289 t level of variable selection stability over time was observed with LightGBM models.

290 wed that humidified systems have slower real time water diffusion compared to anhydrous systems.

291 Often times we find ourselves wrestling with the urge to commi

292 Here, for the first time, we present a method of transient as well as stable

293 studies: benzotriazole (80% interquantile of time-weighted average concentration: 250-4800 ng/L), car

294 The primary outcome was time-weighted average of hypotension during surgery, wit

295 ns who were at the same hospital at the same time were matched for sex, age, and residence.

296 Structural biology is entering an exciting time where many new high-resolution structures of large

297 re students to relocate or be available full time, which is not feasible for students who have family

298 population norms but tended to improve with time, while mental quality of life did not differ signif

299 The precise time window during which spring weather advances phenolo

300 hese regulatory strategies (bursting and the time window) respond in different ways to input transcri