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1 perture, thus altering its ICR response in a time dependent manner.
2 r T cell stimulation, in particular not in a time dependent manner.
3 increased Sgk1 mRNA expression in a dose and time dependent manner.
4 bunit CaV1.1) isoforms changed in a dose and time dependent manner.
5 on on mesoderm specification in a dosage and time dependent manner.
6 s RPTP-kappa mRNA and protein, in a dose and time dependent manner.
7 -targeted carriers accumulated in brain in a time dependent manner.
8  ear epithelial cells (HMEECs) in a dose and time dependent manner.
9 AuNPs can bind to GO in a concentration- and time-dependent manner.
10 ect genotypic rankings of transpiration in a time-dependent manner.
11 d HaCaT (human keratinocytes) in a dose- and time-dependent manner.
12  of MOG-specific CD4+ T cells in a dose- and time-dependent manner.
13 EVO induced cell cycle arrest in a dose- and time-dependent manner.
14 lin mutant, suppressed NCKX4 activation in a time-dependent manner.
15 e found to produce multiple LPA species in a time-dependent manner.
16 glandin E2 (PGE2) accumulates in the CM in a time-dependent manner.
17 ed neurite outgrowth in vitro in a dose- and time-dependent manner.
18 ace of transfected cells also increased in a time-dependent manner.
19  intestinal HuTu-80 cell line in a dose- and time-dependent manner.
20 f infected M1 and M2 markedly increased in a time-dependent manner.
21 ved capase-3 and cleaved PARP in a dose- and time-dependent manner.
22  were transported across hCMEC/D3 cells in a time-dependent manner.
23 generation in the nigrostriatal pathway in a time-dependent manner.
24 l gamma oscillations in a concentration- and time-dependent manner.
25 oteolysis in activated plasma in a dose- and time-dependent manner.
26 n increased in a shear stress magnitude- and time-dependent manner.
27 hoblasts and explant cultures in a dose- and time-dependent manner.
28 ut not unstimulated CLL cells in a dose- and time-dependent manner.
29 ct the memory B-cell response in a dose- and time-dependent manner.
30  substantially in the remaining samples in a time-dependent manner.
31 rize the inflammatory phenotype of MSCs in a time-dependent manner.
32 ological variables did behave in a mixed and time-dependent manner.
33 ellular carcinoma (HCC) cells in a dose- and time-dependent manner.
34  large-scale changes in gene expression in a time-dependent manner.
35 ar endothelial cells in a concentration- and time-dependent manner.
36 ry mouse and human astrocytes in a dose- and time-dependent manner.
37 se-1, catalase, superoxide dismutase-1) in a time-dependent manner.
38 l lines (MiaPaCa and Colo357) in a dose- and time-dependent manner.
39 F-alpha inhibited TRPC6 mRNA expression in a time-dependent manner.
40 d the expression of cyclin D1 in a dose- and time-dependent manner.
41 GABA and ACEI activity of LSF increased in a time-dependent manner.
42 ed globus pallidus and substantia nigra in a time-dependent manner.
43 jected sites to connected brain regions in a time-dependent manner.
44 lation of histone H3 on Ser10 in a dose- and time-dependent manner.
45 cassette transporter in a concentration- and time-dependent manner.
46 ptosis and lipid metabolism is observed in a time-dependent manner.
47 ic smooth muscle cells (HASMCs) in a delayed time-dependent manner.
48 uated the renal manifestations of ARPKD in a time-dependent manner.
49 centration of NO and nitrite, in a dose- and time-dependent manner.
50 e lung injury in C57BL/6 mice in a dose- and time-dependent manner.
51 rhans cells of the epidermis, in a dose- and time-dependent manner.
52 ivation of NF-kappaB and PI3K in a dose- and time-dependent manner.
53 ls in a concentration-dependent and exposure time-dependent manner.
54 y on serines/threonines, in an EPO dose- and time-dependent manner.
55 association with ECP in a concentration- and time-dependent manner.
56 int) transmit to and flavor breast milk in a time-dependent manner.
57 ponse increased in a shear stress force- and time-dependent manner.
58 K-MEL-28 human melanoma cells in a dose- and time-dependent manner.
59 bility and induced cell death in a dose- and time-dependent manner.
60 tion of the GFP reporter gene in a dose- and time-dependent manner.
61 Fs) reduced synaptic activity in a dose- and time-dependent manner.
62 etate, acetyl ester, in a concentration- and time-dependent manner.
63 ing atherosclerotic condition in an exposure time-dependent manner.
64 microvascular endothelial cells (HBMEC) in a time-dependent manner.
65 mbryonic fibroblasts in a concentration- and time-dependent manner.
66  upregulation of MMP-7 mRNA and protein in a time-dependent manner.
67  PAF released PGE(2) in a concentration- and time-dependent manner.
68 ondrial superoxide generation in a dose- and time-dependent manner.
69 mulated miR143/145 expression in a dose- and time-dependent manner.
70 ERAF was the strongest predictor for LRAF in time-dependent manner.
71 modulates the unfolded protein response in a time-dependent manner.
72 m placental villous explants, in a dose- and time-dependent manner.
73 hrine increased ATP release from pieces in a time-dependent manner.
74 ury induced cell death and loss of sGAG in a time-dependent manner.
75 n increased after pulsed acid treatment in a time-dependent manner.
76  protein 22-alpha (SM22alpha) in a dose- and time-dependent manner.
77 nhancer and the -4.0 kb promoter region in a time-dependent manner.
78  of promoter-bound NF-kappaB components in a time-dependent manner.
79  (ZEB2) to be up-regulated in a GH dose- and time-dependent manner.
80 eta mRNA, protein, and iPLA(2) activity in a time-dependent manner.
81 l apoptosis was observed in both a dose- and time-dependent manner.
82 prevents self-administration of cocaine in a time-dependent manner.
83 h FDG distribution differed in a tissue- and time-dependent manner.
84 ion with X4 and R5 tropic HIV in a dose- and time-dependent manner.
85 itional measures of apoptosis in a dose- and time-dependent manner.
86 d both the kinase and the cotransporter in a time-dependent manner.
87 ed DAT function in a concentration-, but not time-dependent manner.
88 ransactivation occurred in tonicity and in a time-dependent manner.
89 SCGF/CLEC11A transcriptional expression in a time-dependent manner.
90 milarly, FGF-2 expression was increased in a time-dependent manner.
91 oxic (to PC12 cells) in a concentration- and time-dependent manner.
92 l and synaptic NMDAR currents in a dose- and time-dependent manner.
93 o stimulates the phosphorylation of Akt in a time-dependent manner.
94 e monolayer and raft cultures in a dose- and time-dependent manner.
95 eir counterparts in vivo, lose imprints in a time-dependent manner.
96                  Periodontitis develops in a time-dependent manner.
97 ct and intrinsic programs in a position- and time-dependent manner.
98 reases ABCA12 mRNA expression in a dose- and time-dependent manner.
99 n into a functional astrocyte-like cell in a time-dependent manner.
100 atus and antibiotic use were determined in a time-dependent manner.
101 ty of human cancer cell lines in a dose- and time-dependent manner.
102  to gadopentetate dimeglumine in a dose- and time-dependent manner.
103 orylation of Tyr-1068 of EGFR in a dose- and time-dependent manner.
104 psilon penetrated HNSCC cells in a dose- and time-dependent manner.
105 ted tyrosine phosphorylation of STAT-5B in a time-dependent manner.
106 ptotic in HT-29 and RKO cells in a dose- and time-dependent manner.
107 llular proliferation in a concentration- and time-dependent manner.
108 TAT1 phosphorylation in a concentration- and time-dependent manner.
109  mouse epidermal JB6 P+ cells in a dose- and time-dependent manner.
110 ve prostate cancer cell lines in a dose- and time-dependent manner.
111  within POMC and AgRP neurons in a dose- and time-dependent manner.
112  in cultured neurons and glia decreases in a time-dependent manner.
113 xpressing breast cancer cells in a dose- and time-dependent manner.
114 t increase in the calcium level in dose- and time-dependent manner.
115 g rainbow trout fry) in a dose-dependent and time-dependent manner.
116 toma cells and HFLCs in a dose-dependent and time-dependent manner.
117 saccade properties and target selection in a time-dependent manner.
118 n IL-12 (p70) in a dose- (0 to 10 ng/mL) and time-dependent manner.
119 lets and in clonal beta cells in a dose- and time-dependent manner.
120  survival as well as migration in a dose-and time-dependent manner.
121 cle regulators CCND1, CDKN1A and CDKN2D in a time-dependent manner.
122 ncreases TrkB phosphorylation in a dose- and time-dependent manner.
123 lated insulin-stimulated glucose uptake in a time-dependent manner.
124  dynamic contacts with these organelles in a time-dependent manner.
125 s in a subtle but reproducible, specific and time-dependent manner.
126  of bladder cancer 5637 cells in a dose- and time-dependent manner.
127 ownregulated cel-mir-237 levels post IR in a time-dependent manner.
128 (+) compartments in wild-type platelets in a time-dependent manner.
129 d changed microbial functional pathways in a time-dependent manner.
130 activity in the central clock in a circadian time-dependent manner.
131 do-lysosomal compartment for processing in a time-dependent manner.
132 TFL1) was upregulated by ATRA in a dose- and time-dependent manner.
133 ity reached its maximum at 40 degrees C in a time-dependent manner.
134 ncer cells in a concentration and incubation time-dependent manner.
135 pressed LPS-induced responses in a dose- and time-dependent manner.
136 ctivity levels; this occurred in a dose- and time-dependent manner.
137 tive impact of breast cancer treatments in a time-dependent manner.
138 ibits cytochrome P450 (CYP) 3A4 and 3A5 in a time-dependent manner.
139 ducanumab reduces brain Abeta in a dose- and time-dependent manner.
140  presence of alcohol in a concentration- and time-dependent manner.
141 aine-modulates vulnerability to cocaine in a time-dependent manner.
142  survival as well as migration in a dose-and time-dependent manner.
143 e most significantly elevated in a dose- and time-dependent manner.
144 ations, cleaved SPINK6 in concentration- and time-dependent manner.
145 ified lipases and their lipase activity in a time-dependent manner.
146 vents involved in LPS-induced tolerance in a time-dependent manner.
147 PSCs, the expression of ORAI1 increased in a time-dependent manner.
148  release of histones in a dose-dependent and time-dependent manner.
149 ased infarct size and fibrin deposition in a time-dependent manner.
150 quitination in vitro in a concentration- and time-dependent manner.
151  SIRT2 substrate, in both concentration- and time-dependent manners.
152 lar smooth muscle contraction in distinctive time-dependent manners.
153 of Transcription 3 (STAT3) in both dose- and time-dependent manners.
154 rylation of JAKs and STAT3 in both dose- and time-dependent manners.
155 sed after ischemia in both cell-specific and time-dependent manners.
156 specific Vgamma2Vdelta2 T cells in dose- and time-dependent manners.
157 ymphal infection prevalence in a cumulative, time-dependent manner (2 and 5 years, respectively), whe
158 l induced cell death in a concentration- and time-dependent manner; 24-hour incubation with 30 microM
159 ut reduced cell proliferation in a dose- and time-dependent manner, accompanied by PPARgamma-activati
160 ation in the aqueous humor was elevated in a time-dependent manner after freezing.
161 l stimulation can facilitate locomotion in a time-dependent manner after lesion.
162 ls increased in the regenerating livers in a time-dependent manner after PHx.
163 activity, and this activity was reduced in a time-dependent manner after traumatic noise injury.
164          25(OH)D3 and 1alpha,25-(OH)2D3 at a time-dependent manner alter cell morphology towards oste
165 s of ceramide-1-phosphate (C1P) dropped in a time-dependent manner although mRNA and protein levels o
166 thdrawal increased later alcohol intake in a time-dependent manner, an effect that may be related to
167  basolateral localization in MDCK cells in a time dependent manner and was essential for pronephric d
168 ment can increase SDF-1 pre-mRNA levels in a time-dependent manner and actinomycin D treatment can ab
169 tivates p35 promoter activity in a dose- and time-dependent manner and concomitantly up-regulates Cdk
170   These global phenotypic changes occur in a time-dependent manner and confer electroexcitability to
171 e SCs to RM induced autophagy in a dose- and time-dependent manner and decreased the accumulation of
172 egrade both soluble and insoluble Abeta in a time-dependent manner and markedly eliminate thioflavine
173  of cortactin on Y421 and Y446 residues in a time-dependent manner and phosphorylation at Y446 but no
174 increases miRNA23b expression in a dose- and time-dependent manner and represses the association of M
175  brain MvEC induced apoptosis in a dose- and time-dependent manner and that prior irradiation signifi
176 to selective lysine residues on albumin in a time-dependent manner and the level of binding correlate
177 rc was co-immunoprecipitated with beta3 in a time-dependent manner and underwent progressive activati
178 increased cardiomyocyte O-GlcNAc levels in a time-dependent manner and was associated with decreased
179 A caused CD36 down-regulation in a dose- and time-dependent manner and was long lasting.
180 L]-1B, IL-6, IL-8, and IL-10) increased in a time-dependent manner and were significantly higher than
181    GL15 interacted with both sequences, in a time dependent manner, and G-quadruplex formation was de
182                MCP1 also activated Rac1 in a time-dependent manner, and depletion/inhibition of its l
183 tatory neurotransmission in an activity- and time-dependent manner, and determined the sign (inhibiti
184 eam, MCP1 activates CCR2 and Galphaq/11 in a time-dependent manner, and down-regulation of their leve
185  release from HVSMCs in a concentration- and time-dependent manner, and early addition of epinephrine
186 tion of cystic cholangiocytes in a dose- and time-dependent manner, and inhibited cyst growth in thre
187  of cortactin on S405 and S418 residues in a time-dependent manner, and inhibition of its phosphoryla
188 S disrupted barrier integrity in a dose- and time-dependent manner, and prior broad spectrum PTK inhi
189 IL-6-induced STAT3 activation in a dose- and time-dependent manner, and suppressed transcription of S
190 duces CREBH acetylation in mouse livers in a time-dependent manner, and this event is critical for CR
191 stitutive activation of STAT3 in a dose- and time-dependent manner, and this inhibition was not cell
192 ty in the ARMS cells in vitro in a dose- and time-dependent manner, and upregulated expression of NF-
193 ophagy, increased ACV numbers in a dose- and time-dependent manner associated with increased levels o
194 tion of MMP1, MMP8, and RANKL in a dose- and time-dependent manner; blocking EDNRA function with the
195 ates a high demand for mRNA translation in a timing-dependent manner, but its underlying mechanism re
196                    Inhibition proceeded in a time-dependent manner by a covalent, irreversible mechan
197 cellular Fn, and is augmented in a dose- and time-dependent manner by plasma Fn.
198 remotor and motor neurons are modulated in a time-dependent manner compatible with an "urgency" signa
199 ibit HRV16 infectivity in a temperature- and time-dependent manner consistent with the breathing beha
200 as greatly elevated, following a dose- and a time-dependent manner, correlating with increased cell p
201 ine residue of a diserine DCF substrate in a time-dependent manner, culminating in monophospho- to tr
202 it the seeding of alpha-syn aggregation in a time-dependent manner, decreased alpha-syn seed-induced
203  by GTPgammaS occurs in a concentration- and time-dependent manner, does not occur in response to GMP
204 at whereas SQSTM1/p62 levels fluctuated in a time-dependent manner during autophagy, inhibition or kn
205 pression levels concomitantly increased in a time-dependent manner during fungal asthma.
206 sociated with the Sestrin2-AMPK complex in a time-dependent manner during ischemia, whereas this inte
207 hosphorylated at tyrosine 877 in a dose- and time- dependent manner following exposure to X-rays, and
208 und that microRNA-21 (miR-21) increases in a time-dependent manner following SCI in mouse.
209 ir tissue-specific epigenetic landscape in a time-dependent manner following the tissue's exposure to
210 nd A3 were S-glutathionylated in a dose- and time-dependent manner following treatment of mice with d
211 3 and C5 were cleaved by FSAP in a dose- and time-dependent manner generating functional C3a and C5a
212               We also demonstrate that, in a time-dependent manner, IBV effectively interferes with I
213 tiproliferative activity to doxorubicin in a time-dependent manner (IC(50) = 77 nM in CCRF-CEM cells)
214 MoDCs by HIV-1 Tat (i) occurred in dose- and time-dependent manners, (ii) was mediated by the N-termi
215          We show that BMPs act in a dose and time dependent manner in which early reduction of BMPs r
216 togen-activated protein kinases (MAPKs) in a time- dependent manner in those HCECs.
217 over, CaMKK2 expression is up-regulated in a time-dependent manner in a carcinogen-induced HCC mouse
218 induced by LPS-TLR4 signaling in a dose- and time-dependent manner in AMPhi from C57BL/6 mice, while
219 ignal by caspase-3 activation in a dose- and time-dependent manner in D54-CR tumor-bearing mice but n
220 ein and the activation of AKT in a dose- and time-dependent manner in different cell lines with or wi
221 t nilotinib induced autophagy in a dose- and time-dependent manner in HCC cell lines, including PLC5,
222 nt cellular uptake of FLG+RMR in a dose- and time-dependent manner in HEK cells.
223  that miR-15b is up-regulated in a dose- and time-dependent manner in human bronchial epithelial cell
224 E induced MMP-2 expression and activity in a time-dependent manner in human dermal microvascular endo
225     15(S)-HETE induced Egr-1 expression in a time-dependent manner in human dermal microvascular endo
226    VEGF induced cPLA(2) phosphorylation in a time-dependent manner in human retinal microvascular end
227 ulated tyrosine phosphorylation of Jak2 in a time-dependent manner in human retinal microvascular end
228 ly modestly increased in a brain region- and time-dependent manner in neonatally infected rats; howev
229 3 mRNA and protein expression in a dose- and time-dependent manner in normal keratinocytes.
230 at hypoxia induced TNF-alpha expression in a time-dependent manner in osteoblasts.
231 sed by L-DOPA or decreased by reserpine in a time-dependent manner in response to in vivo administrat
232 double-strand breaks (DSBs), accumulate in a time-dependent manner in the drug-sensitive MCF-7 cells
233 d 2, induced TF expression and activity in a time-dependent manner in the human monocytic cell line T
234  and vascular endothelial growth factor in a time-dependent manner in the kidneys of adult mice.
235 in control animals but were upregulated in a time-dependent manner in the oligodendroglial lineage wi
236 clofenac accumulated in a concentration- and time-dependent manner in the plasma of exposed fish.
237 gregation, the fluorescence is quenched in a time-dependent manner in three distinct phases: an early
238 ulated tyrosine phosphorylation of EGFR in a time-dependent manner in vascular smooth muscle cells (V
239                 Thrombin activated RhoA in a time-dependent manner in VSMCs.
240 e the relationship between RVI and CLAD in a time-dependent manner, incorporating different periods o
241 sitized prostate cancer cells in a dose- and time-dependent manner, increasing apoptotic cell death a
242 h the RNA and protein levels, in a dose- and time-dependent manner, indicating that KLF4 transcriptio
243 almitoylation or that they are consumed in a time-dependent manner into high molecular weight aggrega
244  domain of a protein in a concentration- and time-dependent manner is of high value.
245 p2 cells and accumulate intracellularly in a time-dependent manner, mainly in the cell endoplasmic re
246 active free radicals in a concentration- and time-dependent manner, modulating intracellular redox st
247 abolites increased at a comparable rate in a time-dependent manner over a 60-min assay incubation per
248  synovial fibroblast IL-18BPa and IL-18 in a time-dependent manner (P < 0.05).
249  transcripts of BSP and COL-I in a dose- and time-dependent manner (P <0.001).
250 d the expression of OCN, RunX2, and ALP in a time-dependent manner (P <0.001).
251 uced by CsA was found in HGFs in a dose- and time-dependent manner (P <0.05).
252 1 protein expression in a concentration- and time-dependent manner (P<0.05).
253 mulation of HDHB on chromatin in a dose- and time-dependent manner, preferentially in S phase cells.
254 ansfected into NCI-H292 cells in a dose- and time-dependent manner, resulting in high transfection ef
255 ut to loss of specific nodal components in a time-dependent manner.SIGNIFICANCE STATEMENT Nodes of Ra
256 sion between SCGNs in long-term culture in a time-dependent manner, significantly reducing excitatory
257 (2) strain, whereas VWF:CBA levels drop in a time-dependent manner, suggesting dysfunction of VWF ins
258  assay) by up to 90% in a concentration- and time-dependent manner, suggesting insurmountable antagon
259 y release or uptake serotonin in a dose- and time-dependent manner, suggesting the utility of these c
260 with hormone-activated STAT5A in a dose- and time-dependent manner that coincides with tyrosine phosp
261 ) T cells to infection by HIV in a dose- and time-dependent manner that is independent of receptor an
262 LK7 mRNA expression and protein release in a time-dependent manner that is similar to induction of di
263 alytic recruitment of Rab5A/Rab1A/Rab8A in a time-dependent manner that required the catalytic activi
264  increased aquaporin 2 (AQP2) in a dose- and time-dependent manner that was highly correlated with ce
265 nts promote SNCA accumulation in a dose- and time-dependent manner, thereby identifying a biochemical
266 murine mesenchymal stem cells in a dose- and time-dependent manner through ALK5 and ALK1 pathways, re
267 sion of T-fam and COX subunits I and IV in a time-dependent manner through early phosphorylation of t
268 -induced neurotoxicity in concentration- and time-dependent manners through the inhibition of microgl
269 sly were bound and released by the host in a time-dependent manner, thus allowing multiple states of
270 lation of 14-3-3gamma occur in a coordinated time-dependent manner to regulate 14-3-3gamma homodimeri
271 nd specifically, and in a concentration- and time-dependent manner, to immobilized Bcl-xL(Delta21), a
272        Spinal BDNF expression increased in a time-dependent manner together with NDO emergence.
273 fter a loading dose/maintenance therapy in a time-dependent manner under in vitro testing.
274 monomers to produce aggregates in a dose-and time-dependent manner under static conditions in vitro.
275 transcript and protein levels in a dose- and time-dependent manner up to sixfold, accompanied by a si
276 ctivity of hPLCbeta3 in a concentration- and time-dependent manner; up to an 8-fold increase in enzym
277  necrosis factor-alpha in a biomaterial- and time-dependent manner when compared with MCs that were n
278 ation of cultured adult hNSCs in a dose- and time-dependent manner, whereas apoptosis and differentia
279 heral mononuclear neutrophils in a dose- and time-dependent manner, whereas curcumin enhanced the upr
280 ssociated with mycobacterial phagosomes in a time-dependent manner, whereas siRNA-mediated knockdown
281 o COLO205 cells in a concentration/dose- and time-dependent manner, which correlated well with cell d
282  (such as nucleozin) in a concentration- and time-dependent manner, which suggests that the inhibitor
283 and decreased its mRNA levels in a dose- and time-dependent manner, which was associated with a decre
284  COX-2, cIAP2, XIAP, and IL-8 in a dose- and time-dependent manner, which was mediated by phosphoryla
285 es MAO B promoter in both concentration- and time-dependent manners, which is mediated through retino
286 imary hepatocytes in both dose-dependent and time-dependent manners, which was independent of AMPK ph
287 that VitC wield antibacterial action in dose-time dependent manner with minimum inhibitory concentrat
288 thelial cells in a specific, reversible, and time-dependent manner with a K(d) of 58 nm.
289      It inactivates P450 2B4 in a NADPH- and time-dependent manner with a K(I) of 0.44 microM and k(i
290 R-3 ovarian cancer cells in both a dose- and time-dependent manner with effective concentrations rang
291 potent inhibitor able to inhibit this DUB in time-dependent manner with k(inact) = 0.065 min(-1) and
292 , psilocybin-induced changes correlated in a time-dependent manner with spatial gene expression patte
293         DvSnf7 suppression was observed in a time-dependent manner with suppression at the mRNA level
294 e Locators (URLs) linking to them decay in a time-dependent manner, with approximately 27% decayed to
295 d CCL7 in astrocytes in a concentration- and time-dependent manner, with CCL2 showing a more rapid an
296 eability to albumin in the same vessels in a time-dependent manner, with changes in all three true ve
297 ome production and/or release in a dose- and time-dependent manner, with greater effects in ovarian c
298        HIV induced pyroptosis in a dose- and time-dependent manner within podocytes, a phenotype of i
299 re similarly labile and (re)established in a time-dependent manner within the brain through processes
300 th soluble and fibrillar Abeta peptides in a time-dependent manner, yielding specific degradation pro

 
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