ライフサイエンスコーパス: to access

1 ompounds that often require extensive effort to access.

2 last biological frontiers as it is difficult to access.

3 etic information that is otherwise difficult to access.

4 ryl derivatives that are otherwise difficult to access.

5 ared here) that would otherwise be difficult to access.

6 aromatic hydrocarbons, they can be difficult to access.

7 cated in lymphoid tissues that are difficult to access.

8 ayer sufficiently sized for a single IgG Fab to access.

9 Here we report a general method to access 1,3-C-disubstituted BCPs from 1-iodo-bicyclo[1

10 nated BODIPYs, we further functionalize them to access 13 new, BODIPY-based, voltage-sensitive fluoro

11 eps in 10 unique modules, with the code able to access 17 different reactions.

12 essential carbon framework of the austalides to access (+/-)-17 S-dihydroaustalide K, (+/-)-austalide

13 ic utility of the strategy has been revealed to access 2,3-dihydrobenzo[d]thiazoles.

14 ve developed an efficient synthetic strategy to access 2,5-diaryl nonsymmetric furans from 5-hydroxym

15 C(sp(2))-H] with dialkyl phosphites [P(O)-H] to access 2-phosphonated azoles using Cu(I)/Cu(II) as ca

16 t are otherwise impossible or more difficult to access [5, 6].

17 We envisage that our reported protocol to access 7-amino-4-methylcoumarin derivatives will find

18 up could be functionalized at the 4-position to access a binding pocket that can accommodate both pol

19 nity offers numerous advantages, the ability to access a glassy state with distinct properties provid

20 We applied a multicomponent approach to access a library of densely functionalized homo- and

21 ophilic SCN source offered an efficient tool to access a panel of functionalized isothiazolone deriva

22 ble synthetic roadmap for medicinal chemists to access a range of fluorinated therapeutic candidates

23 These new molecules serve as a foundation to access a range of new pyridinophane small molecules a

24 ly be cleaved under mildly acidic conditions to access a range of valuable substituted cyclohexene de

25 We observe that haematite is able to access a reaction mechanism that is third order in su

26 l that both classes of projection allow GSCs to access a reservoir of Dpp held away from the GSC-nich

27 ch each individual in a dyad received a tool to access a reward, but tools could not be used simultan

28 ngements of dearomatized acylphloroglucinols to access a structurally diverse group of synthetic acyl

29 , components which can further react in situ to access a variety of other medicinally relevant functi

30 talytic stereoinversion/deracemization route to access a variety of substituted d-tryptophan analogs

31 This method offers a rapid approach to access a wide range of functionalized [3.3.1]-bridged

32 ize, while taxa with larger genomes are able to access a wider variety of C substrates.

33 H(2) provides a facile and waste-free method to access alcohols and thiols.

34 er mode of activation was therefore selected to access aliphatic sulfonamides, applying a single-step

35 A novel route to access alkynyl sulfoxides is reported herein by using

36 tween trifluoromethylarenes and allylsilanes to access allylated alpha,alpha-difluorobenzylic compoun

37 um-catalyzed hydroaminoalkylation of alkynes to access alpha,beta,gamma-substituted allylic amines in

38 nism utilizing an iron-based catalyst system to access alpha-(N-arylamino)acetic acid equivalents.

39 (2))(4) affords an alternative disconnection to access alpha-arylated primary amines upon aqueous wor

40 investigate the health concerns and barriers to access among migrants experiencing forced displacemen

41 t mining tool, renamed to LAITOR4HPC, aiming to access an unlimited abstract amount in a short time t

42 DV and the related NCBI Sequence Viewer (SV) to access, analyze, and disseminate NCBI and custom biom

43 elopment of DBS has opened new opportunities to access and interrogate malfunctioning brain circuits

44 c and fetal stages-stages that are difficult to access and investigate in humans.

45 fying delivery and reducing current barriers to access and persistence.

46 c and sequencing data present new challenges to access and sharing of genotype-phenotype datasets, in

47 owards the development of integrated systems to access and standardize the dispersed, heterogeneous a

48 oslin Medalist Study has allowed researchers to access and study patients (Medalists) with type 1 dia

49 er-resolution imaging systems, could be used to access and thereby advance our understanding of super

50 ion, allowing only the species best equipped to access and use the limited resources to survive.

51 ht users and workflows; 4) make the CDS easy to access and use; 5) minimize the burden placed on user

52 cally utilizes stochastic lattice-gas models to access appropriate time and length scales.

53 Barriers to accessing appropriate and culturally competent care c

54 , operationally simple approach is presented to access arynes and their fluoride-activated precursors

55 Biofeedback training has been used to access autonomically-controlled body functions throug

56 However, supercoil dynamics are difficult to access because of the wide range of relevant length a

57 erest as versatile synthetic building blocks to access beta-aminoalcohols and other useful compounds,

58 an efficient and straightforward methodology to access bicyclic carbo- and heterocyclic scaffolds com

59 mputational algorithm with synthetic biology to access biologically active small molecules encoded di

60 This method would be attractive to access biologically attractive molecules.

61 a continuing need to develop robust methods to access both early-stage and late-stage organoboron in

62 orm approach in combination with the ability to access both enantiomers from the carbene-catalyzed re

63 A was also achieved through the new approach to access both enantiomers of 4,5-di-O-benzyl-myo-inosit

64 iants have become a valuable tool with which to access both enantiomers of a broad range of chiral ar

65 iRTarBase provides a user-friendly interface to access both predicted and experimentally identified p

66 In this study, the lack of methodology to access both syn and anti diastereomers of optically e

67 regioselective hydrofluorination of alkynes to access both the E and Z isomers of vinyl fluorides.

68 selective TBTQ synthesis opens a new pathway to access building blocks for CAS.

69 (18)F-labeling of agents that are difficult to access by applying traditional radiochemistry, for ex

70 ofluorinated compounds that can be difficult to access by classical S(N)Ar strategies, with the poten

71 value-added products that would be difficult to access by conventional methods.

72 unsaturated tetrazoles, which are difficult to access by other means.

73 lylation/oxa-Michael cascade was implemented to access caesalpinnone A (1) in 7 steps.

74 ated fulvenes that were previously difficult to access can now be obtained in good yields.

75 These patients are less able to access care and more likely to experience poor heart

76 care in both arms were traced and encouraged to access care.

77 paced or stopover movements, perhaps in part to access carrion produced by vehicle collisions.

78 esign and the different synthetic strategies to access cationic polythiophenes (CPTs) via chemical ox

79 also that these relationships enable groups to access certain areas with a reduced risk of aggressio

80 undergo a reductive desymmetrization process to access chiral cyclopentane bearing multiple stereocen

81 e procedure and was noninferior with respect to access circuit-related serious adverse events within

82 ete with other members of the gut microbiota to access citrate in the gut.

83 ant fundamental toolbox in organic synthesis to access complex molecular fragments.

84 can provide a simpler synthetic alternative to access complex structural target molecules.

85 The products can be readily elaborated to access complex tetralene, benzosuberene, and bicyclod

86 /mol), which makes this a promising strategy to access configurationally stable expanded helicenes.

87 he optimized method was successfully applied to access content safety of selected PAHs for 24 kinds o

88 $50 digital cameras) has lowered the barrier to accessing cost-efficient, objective detection methodo

89 "Digital Plant Phenotyping Platform" (D3P), to access crop architectural traits from HTP observation

90 h high-throughput elicitor screening (HiTES) to access cryptic, bioactive metabolites.

91 ng functions; these capabilities allow users to access data via keyword, ID and advanced options comb

92 nd their derivatives will enable researchers to access degradable materials with tunable thermal, phy

93 are a powerful tool for measuring difficult-to-access degrees of freedom in materials science.

94 nucleases can be programmed with guide RNAs to access desirable genomic sites.

95 This study offers a unified method to access diaryl and aryl alkyl thioethers and was demon

96 Predicted materials can be used to access different parts of electron-hole phase diagram

97 an eco-friendly oxidant, reaction tunability to access different products, wide substrate scope, and

98 r prior injection drug use remains a barrier to accessing direct-acting antiviral treatment (DAA) for

99 is an open source platform that can be used to access, discover and disseminate omics datasets.

100 propargyl sulfonamides to p-quinone methides to access diverse diarylmethine substituted dihydropyrro

101 lternative to preactivated allylating agents to access diverse products in a highly selective manner.

102 of N-(pivaloyloxy)benzamides with 1,5-enynes to access diversely substituted aromathecin derivatives

103 methodology followed by polyene cyclization to access DMOA-derived meroterpenoid frameworks in six s

104 A concise synthetic route with the potential to access DMOA-derived meroterpenoids is highly desirabl

105 en microbial phylogeny and function in order to access ecosystem functioning.

106 se of manometer malfunction (n=2), inability to access effusion due to pleural tumour burden (n=1), a

107 stereodivergent strategy has been developed to access either (E)- or (Z)-isomers of trisubstituted e

108 m the cells in the RTN region without having to access either sides of the cell membrane.

109 ealth care systems now offer patient portals to access electronic health records (EHRs) in the United

110 tion constitute an efficient synthetic route to access enantioenriched substituted 2,3-dihydro-1H-pyr

111 The approach described here can be used to access enantiopure 3,4-disubstituted prolinols, which

112 iated by microbial populations in these hard-to-access environments are poorly understood.

113 ensional glass-forming liquids that allow us to access equilibrium states at sufficiently low tempera

114 yloid pathway, however, has been challenging to access for any amyloid protein system.

115 Therefore, the system is easy to access from any location.

116 Now, a simple strategy to access functional MOF NPs in one pot is reported that

117 Herein, a facile diversity-oriented approach to access functionalized benzo[a]fluorenes, benzo[b]fluo

118 el was characterized by rheological analysis to access gelation behavior, and morphology was visualiz

119 onsteroidal anti-inflammatory drugs (NSAIDs) to access H(2)S-NSAID hybrids with significantly reduced

120 elationship of geography and travel distance to access has not been well studied.

121 Patients increasingly use the internet to access health-related information to better understan

122 thyl ketones through a formal [4+2] manifold to access highly enantioenriched dihydrobenzoxazin-4-one

123 We report a chemoenzymatic platform to access highly oxidized diterpenes by a hybrid oxidati

124 e demonstrates the power of electrochemistry to access highly reactive intermediates under mild condi

125 grams may be important venues for rural PWID to access HIV testing; however, testing services should

126 ised countries have to travel long distances to access HIV treatment and few have access to motorised

127 eoselective additions to aldehydes/aldimines to access homoallylic alcohols/amines containing a fluor

128 To access human endocardial cells, we generated a human

129 by the complex bioinformatic steps required to access, import, decrypt, and merge the various compon

130 Drosophila visual system using genetic lines to access individual cell types, the TAPIN-seq method to

131 We then implemented an all-optical approach to access individual quantized electronic-nuclear spin t

132 tes the fourth statistical moment (kurtosis) to access interesting subspaces that can clarify relatio

133 s for reactions of bulky molecules too large to access interior pores.

134 t conventional imaging modalities are unable to access intricate biomolecular information without com

135 A new methodology was developed to access isothiazolone derivatives from simple acrylami

136 lity to degrade Chlorella vulgaris cell wall to access its valuable nutritional compounds.

137 a prerequisite for dialysis-treated patients to access kidney transplantation in Canada, is a subject

138 didates with recurrent falls are less likely to access KT and more likely to experience adverse post-

139 didates with recurrent falls are less likely to access KT and more likely to experience adverse post-

140 ypes several new tools have been implemented to: access large-scale maize diversity data (SNPversity)

141 work, retrofitting, is an effective approach to access lattice dynamics experimentally, in turn provi

142 in a forest determines the ability of trees to access limiting nutrients from atmospheric or soil po

143 o alcohol, a different strategy was required to access lipovelutibol B and a series of N-terminal lip

144 To access low- and high-FR neurons for ex vivo analysis,

145 hyde building blocks with cyclohexanediamine to access low-symmetry imine cages.

146 surance is now recognized as a major barrier to accessing medical care.

147 nd uses an inexpensive organic photocatalyst to access medicinally valuable beta-phenethylamine deriv

148 and regioselective C-H amination of alcohols to access medicinally valuable chiral beta-amino alcohol

149 Here, we report a route to access metal-diamidobenzoquinone frameworks from thei

150 al expression of GCaMP6 reporters allowed us to access mitral cell (MC) and superficial tufted cell (

151 periments as well as atomic force microscopy to access molecular properties of CWPE.

152 n advanced spectroscopic system was employed to access molecule-specific information with nanoscale l

153 d in the first catalytic thioether reduction to access monosubstituted tetrazines.

154 quence exploits the residual directing group to access more than 50 scaffolds that would be otherwise

155 Most users travelled >1 h to access motorised boreholes but <30 min, increasing to

156 Two efficient base-mediated protocols to access multiple naphthofurans, naphthodifurans, and a

157 em-to enable strongly interacting polaritons to access multiple spatial modes of an optical cavity.

158 lts showed that this method is also amenable to access N-thioacyl sulfamates.

159 netic nanoparticles can be deliberately used to access nanostructures beyond what is possible with DN

160 An easy-to-access, near-UV-emitting linearly extended B,N-doped

161 ate that this method can serve as a platform to access new architectures of n-type CPs without the ne

162 nce in terms of late-stage functionalization to access new molecular entities which can be employed i

163 m the continued design of catalysts for ROMP to access new polymer architectures and materials.

164 th hydrophobic cores that in turn allow them to access novel activities.

165 we have been able to use this transformation to access novel analogues of the clinical drug candidate

166 Multitarget synthetic strategies to access novel photochromic 3H-naphtho[2,1-b]pyrans dec

167 nce settings provides a powerful opportunity to access novel therapeutic biomarkers in the TME.

168 e mechanisms that gut symbionts have evolved to access nutrients and the potential for unexpected dep

169 associated microbes depends on their ability to access nutrients in vivo.

170 ch ectomycorrhizal (ECM) fungi enable plants to access organic nitrogen (N) bound in soil organic mat

171 t delivers versatile and otherwise difficult-to-access organoboron entities by combining an allenylbo

172 ationally simple, double ion-exchange method to access organosulfates and sulfamates.

173 of lattice control would enhance the ability to access other phases.

174 ded version of the Corey-Chaykovsky reaction to access oxazolines using sulfur ylides and stable prec

175 ross different gene annotation versions, and to access P. patens annotations and related resources, a

176 A synthetic route to access phevalin and similar pyrazinone natural produc

177 Auditory speech perception enables listeners to access phonological categories from speech sounds.

178 It is often difficult to access primary human brain tissue; therefore, approxi

179 or efforts that require obtaining permission to access private property and spray yards.

180 People with AMD often find it difficult to access, process and understand written patient educat

181 An efficient, metal-free approach to access pyrazolo-[1,5-c]quinazolines with 3-ylideneoxi

182 erein we disclose a three-component strategy to access quaternary centers bearing nitriles by cobalt-

183 and the release of a command-line interface to access, query and analyze data.

184 We report a novel strategy to access RCF(2)Br-containing heterocycles by regio- and

185 organic optoelectronic materials is crucial to access real life applications.

186 To access reliable visual signals in dim-light environme

187 ices single application programing interface to access remotely from applications.

188 es it possible for histone-modifying enzymes to access residues within the nucleosome core.

189 or deflecting near-Earth objects (NEOs), and to access resources that would enable space habitats and

190 Bacteroidetes and appear to have diversified to access ribose from a variety of substrates.

191 e sex before marriage, and increase barriers to accessing sexual and reproductive health.

192 Finally, 1 is further demonstrated to access similar capacities as a sodium-ion or potassiu

193 ften be valuable in principle, but difficult to access simultaneously.

194 procedural death and complications according to access site, except for a 2-fold lower rate of major

195 requency, bio-surveillance at remote or hard to access sites.

196 ned with the strategy of divergent synthesis to access six different natural product classes from a s

197 lockdown, individuals use their smartphones to access social support, which may help guard against n

198 Here, we present a general approach to access solid-state CNT mimic structures via the self-

199 iaturized frequency comb sources across hard-to-access spectral regions, i.e. mid- and far-infrared,

200 , significantly fewer strategies are defined to access stereocentres that incorporate a tertiary C-F

201 on in a cascade- or sequence-specific manner to access structurally complex, natural-product-like het

202 anotubes (CNTs) in particular, the inability to access structures with specific diameters or chiralit

203 An atom-economical methodology to access substituted acyl-cyclohexenes from pentamethyl

204 We report an electrochemical method to access such hindered amines starting from benchtop-st

205 ver, rationalization of the limiting factors to access such regimes is still lacking.

206 ndirect health-care costs were a key barrier to accessing surgical care, prompting 3.1 million (6.4%

207 f biomolecules-remain enormously challenging to access synthetically owing to poor aqueous solubility

208 on here proceeds without air-free techniques to access synthetically useful borylated thiophenes, ben

209 In addition, we used A MeaSurement Tool to Access systematic Reviews 2 (AMSTAR 2) to evaluate th

210 nthetic planning into their overall approach to accessing target molecules.

211 To access targets within cells, a cyclic cell-penetratin

212 is proposed.(Posted July 6, 2020)Click HERE to access Teaching Tool ComponentsRECOMMENDED CITATION S

213 selves.(Posted September xx, 2019)Click HERE to access Teaching Tool ComponentsRECOMMENDED CITATION S

214 roteins.(Posted December 10, 2019)Click HERE to access Teaching Tools ComponentsRECOMMENDED CITATION

215 e to the five- to seven-hour travel required to access testing and treatment.

216 can potentially permit blood-borne pathogens to access the brain(2).

217 irculation and cross the blood-brain barrier to access the brain, initiate feed-forward amyloid trans

218 res precisely removing sections of the skull to access the brain.

219 ll-penetrating sequence allowed the peptides to access the cell interior and engage with their target

220 he optimized method was successfully applied to access the content safety of the PAHs studied in a va

221 A different strategy was required to access the core on the integrastatins; an initial ary

222 e tools with different visualization methods to access the data.

223 Readers who wish to access the definitive published version of this manus

224 ed multiscale molecular dynamics simulations to access the dynamics of the glucagon receptor (GCGR) E

225 To access the effect of nucleosome turnover on the epige

226 The evolution of a strategy to access the family of rearranged spongian diterpenoids

227 HIP uses the NVIDIA CUDA interface to access the GPU.

228 to bind to the IPKS and enable the trans MT to access the growing polyketide.

229 Here we show how to access the hydration shell structures around colloida

230 , which present a more suitable model system to access the impact of membrane physical properties on

231 use of commercial chopstick-like electrodes to access the impedance of a barrier cultivated in trans

232 A CBCT exam allowed to access the initial buccal bone thickness (BT).

233 human populations require special attention to access the international supply of ventilators.

234 creases permeability, allowing nanoparticles to access the microenvironment.

235 econd-generation strategy was then developed to access the more highly oxidized majucinoid compounds

236 ss an essential L-protein cofactor, required to access the N-RNA template and coordinate the various

237 hoton excitation (2PE) is typically required to access the near-infrared window.

238 proteins and restriction enzymes are unable to access the phage DNA throughout the infection, but en

239 provides a rapid and enantioselective route to access the polysubstituted tetrahydronaphthalene core

240 of our drug discovery programs, we had need to access the previously unknown 5-dihydropyrazolo[3',4'

241 tal microbalance with dissipation monitoring to access the real-time kinetics and elementary solubili

242 astereoselective Pictet-Spengler methodology to access the required trans-stereochemistry.

243 tes TRPA1 by penetrating the plasma membrane to access the same intracellular site modified by reacti

244 en with 4d metals, and the ability of solids to access the same redox couple at two very different po

245 selective functional group interconversions to access the structurally complex linker-attached trisa

246 Attempts to access the three-coordinate aluminyl by abstraction o

247 last several decades, exploring the pathways to access the triplet excited states of organic chromoph

248 To allow bats to access their roosts, metal corrugated culvert pipes a

249 matic amino acids, and also nickel-complexes to access them.

250 report a divergent enantioselective strategy to access these alkaloids by use of a challenging pallad

251 However, inability to access these cells from patients, particularly at ear

252 his Review on the synthetic methods employed to access these compounds, their structural features, ma

253 azetidines, which represents a new approach to access these highly desirable synthetic targets.

254 e development of new synthetic methodologies to access these molecules.

255 ir therapeutic potential, a general strategy to access these natural products in a concise and diverg

256 dependent sources and researchers often need to access these separately.

257 talysis as a convenient and general approach to access these substructures.

258 One potential yet underdeveloped approach to access these trifluoromethylated products is direct s

259 -step chemical syntheses have been developed to access these unique compounds.

260 addition of an N-alkenylnitrone and an aryne to access these unusual transient rearrangement precurso

261 attention and several innovative strategies to access these valuable functional groups have been dev

262 ich membranes and warps the membrane surface to access this cargo.

263 Synthetic procedures to access this family of natural products will enable fu

264 ethods of efficient chemical dehydrogenation to access this fuel.

265 is not trained in structural bioinformatics to access this information comprehensively.

266 ic methods, thus opening up a versatile path to access this previously largely obscure class of fulve

267 , non-Maori-speaking New Zealanders are able to access this proto-lexicon to distinguish Maori words

268 To access this regime we generalize both the hierarchica

269 stry, yet few enantioselective methods exist to access this scaffold.

270 the development of a Mizoroki-Heck reaction to access this spirolactone core.

271 troscopy (LFRS) are complementary approaches to accessing this spectral region and are valuable tools

272 ectrophysiological sensors with the ambition to access thousands of cortical points at near-cellular-

273 se automated systems are becoming so crucial to access to health, researchers in the field of artific

274 lation density in state of Florida in regard to access to TAVR, TAVR utilization rates, and in-hospit

275 e design of artificial metalloenzymes (ArMs) to access transformations not observed in nature remains

276 ve been averted if all individuals were able to access treatment within the first day of symptom onse

277 d to estimate the minimum travel time needed to access treatment, for every person living with HIV in

278 stry and indicate that neutrophil thresholds to access treatments could be lowered in individuals wit

279 substrates, thus bestowing a powerful avenue to access tri- and tetrasubstituted pyridines including

280 we report optimization of a synthetic route to access triazole-containing DBOs and biological evalua

281 telechelic polypropylene (PP) and their use to access triblock amphiphilic copolymers with the PP bl

282 t provide insights into the diverse pathways to access triplet excited states in organic chromophores

283 oselectivity; these products are challenging to access under mononuclear metal-catalyzed hydrostannyl

284 tivity-dependent evolution can be engineered to access unforeseen routes of improving metabolic pathw

285 ust be consistently engaged in care and able to access uninterrupted treatment, including ART.

286 building blocks provides great opportunities to access unknown assemblies.

287 s so that a broader range of people are able to access/use scientific research, and (2) to expose sci

288 meric excess), which otherwise are difficult to access using chemocatalysis.

289 (meta) substitution patterns are challenging to access using the Diels-Alder reaction (the ortho-para

290 With a view to upgrading carbohydrates to access valuable nitrogen-containing sugar-like compou

291 olefination and alkynylation is established to access valuable phenylacetamido-2-pyridones.

292 cessfully been developed for these reactions to access various amines.

293 pt results on a versatile synthetic strategy to access various linearly segmented nanowire heterojunc

294 his illustrates the potential of VirtualFlow to access vast regions of the chemical space and identif

295 d mechanism, in a manner otherwise difficult to access via classical substituent effects.

296 e products, some of which would be difficult to access via currently established methods.

297 ne products that contain otherwise difficult-to-access vicinal beta-tertiary and gamma-quaternary car

298 ons afforded by photo-RDRP, make it possible to access well-defined peptide-based polymer bioconjugat

299 mplex molecular scaffolds that are difficult to access with reactions in the electronic ground state.

300 e and convenient route has been demonstrated to access (Z)-1,2-diazido alkenes from the corresponding