ライフサイエンスコーパス: toenail

1 asure trace elements and their speciation in toenails.

2 based on concentrations in the participants' toenails.

3 or severe hypoplasia of all fingernails and toenails.

4 Fifteen patients (23%) developed brittle toenails after a median of 9 (95% CI, 6-15) months of ib

5 Using GW-summary statistics from both toenail and blood Se, we observed statistical evidence o

6 include skin, dental, wound, stomach, nasal, toenail and other infections which are amenable to effec

7 ametric Spearman's rank correlations between toenail and serum biomarker levels.

8 oman maintenance of rank across time for the toenail and serum measures and fit mixed effects models

9 By contrast, three foot sites--plantar heel, toenail and toe web--showed high fungal diversity.

10 Among 208 subjects with both toenail and water measurements, the correlation (r) betw

11 y diarrhea, alopecia, and a complete loss of toenails and fingernails, the patient had been suffering

12 and her father had a history of shedding of toenails and occasional poorly healing erosions, consist

13 ed the association between mercury levels in toenails and the risk of coronary heart disease among ma

14 2 trace element concentrations measured from toenails and the risk of non-muscle invasive bladder can

15 , Rb, S, Sr, Ti, and Zn) in dirty and washed toenails and the speciation of As in situ in toenails we

16 Hair, toenail, and fingernail are noninvasive, integrative bio

17 tope ratios and U concentration in the hair, toenail, and fingernail of cases were compared to a none

18 Paired human hair, fingernail, toenail, and serum samples obtained from 50 adult partic

19 Arsenic in drinking water and toenails, and skin lesion status and severity were ascer

20 Aging Study to analyze associations between toenail arsenic and QT and heart rate-corrected QT (QTc)

21 k of melanoma for participants with elevated toenail arsenic concentrations (odds ratio = 2.1, 95 per

22 Among individuals with toenail arsenic concentrations above the 97th percentile

23 A study was conducted to evaluate toenail arsenic concentrations as a biologic marker of d

24 f SCC and BCC did not appear elevated at the toenail arsenic concentrations detected in most study su

25 A log10 decrease in toenail arsenic from baseline to follow-up was also sign

26 The authors examined the relation between toenail arsenic levels and bladder cancer risk among par

27 s, every log10 decrease in water arsenic and toenail arsenic was associated with 22% [odds ratio (OR)

28 An interquartile range increase in toenail arsenic was associated with higher systolic BP [

29 served some positive associations of uAs and toenail As concentrations with biomarkers potentially re

30 -IsoP (95% CI: 3.2, 14.7), and a doubling of toenail As was associated with a 1.7% increase in VCAM-1

31 in contrast with expectations, a doubling of toenail As was associated with a 2.3% decrease (95% CI:

32 Associations between toenail As, total urine As (uAs), and %uAs metabolites [

33 ed cautiously given potential limitations of toenails as biomarkers of metal exposure.

34 Among 146 women who donated both blood and toenails at baseline, a subsample (59%, n = 86) provided

35 Selenium was measured in blood and toenails by neutron activation.

36 At birth, toenail changes were present in 47.5% of patients; finge

37 Toenail chromium concentration was assessed by neutron a

38 Toenail chromium concentration was inversely associated

39 Average toenail chromium concentrations were 1.10 mug/g in cases

40 To determine whether low toenail chromium concentrations were associated with ris

41 aring the highest to the lowest quartiles of toenail chromium levels was 0.80 (0.66-0.98; Plinear tre

42 Toenail chromium levels were inversely and longitudinall

43 Baseline toenail chromium levels were measured with instrumental

44 Baseline toenail chromium was inversely associated with incidence

45 d the joint association of mercury levels in toenail clippings and docosahexaenoic acid (C22:6n-3, or

46 ants completed a mailed survey and submitted toenail clippings for analysis of arsenic content by gra

47 Hg concentrations were analyzed in toenail clippings from a subset of 41 infants; neurobeha

48 total of 51,529 men and 121,700 women) whose toenail clippings had been stored, we prospectively iden

49 Trace element concentrations in toenail clippings have increasingly been used to measure

50 the Nurses' Health Study cohort who provided toenail clippings in 1982.

51 ctively coupled plasma mass spectrometry, in toenail clippings of 1,217 disease-discordant sister pai

52 ling site in south Los Angeles and collected toenail clippings to assess exposure to arsenic (As), ca

53 Arsenic was determined in toenail clippings using instrumental neutron activation

54 Toenail clippings were collected in 1987 from 33,737 coh

55 s, free of diabetes at baseline in 1987 when toenail clippings were collected, were examined for inci

56 s arsenic levels quantified through maternal toenail collected at birth were associated with methylat

57 , we measured concentrations of 15 metals in toenails collected at enrollment in a race/ethnicity-str

58 as matched to each case on the basis of age, toenail collection date, intervention group, and smoking

59 matched with two controls by age and date of toenail collection.

60 Arsenic toenail concentrations in this Finnish study were simila

61 iation between young-onset breast cancer and toenail concentrations of any assessed metals.

62 Toenail conditions, fungal symptoms, and ulcers or lacer

63 endogenous accumulation of trace elements in toenails-contaminated areas were characterized by the co

64 wed the presence of one As species in washed toenails, corresponding to As bound to sulfhydryl groups

65 alence of squalene epoxidase mutations among toenail dermatophyte isolates.

66 verall, the five most common conditions were toenail disorders (74.9%), lesser toe deformities (60.0%

67 2 clusters), 10, and 20 were genotyped using toenail DNA.

68 in 26.7% of patients despite the presence of toenail dystrophy in more than 65.3%.

69 Tail hair, toenail, faeces, plasma and urine were collected quarter

70 is the first time that hair, fingernail, and toenail have been demonstrated to be sensitive to occupa

71 Median toenail Hg in cases and controls, respectively, was 0.06

72 thylation difference > 0.125 between any two toenail Hg tertiles.

73 Toenail Hg was not found to be significantly associated

74 prenatal Hg exposure assessed through infant toenail Hg, placental DNA methylation changes, and newbo

75 measured in drinking water and in subjects' toenails (in 2001-2003) prior to the diagnosis of T2DM (

76 skin diseases, including athlete's foot and toenail infections.

77 ned terminal phalanges with small finger and toenails, intellectual disability, and seizures; this co

78 The within-woman Spearman correlation for toenail iron between the two time points was higher (0.4

79 Toenail iron concentrations did appear to be moderately

80 an association between serum biomarkers and toenail iron levels.

81 prospective Sister Study cohort, we compared toenail iron measures to serum concentrations for iron,

82 e examined the correlation between serum and toenail levels for trace metals.

83 or ordinal trend with increasing quartile of toenail MeHg).

84 trol study, we examined associations between toenail mercury (Hg) and glioma risk.

85 Toenail mercury and selenium concentrations were assesse

86 Median toenail mercury concentrations were 0.23 mug per gram (i

87 The average toenail mercury level in controls was 0.25 microg per gr

88 The toenail mercury level was directly associated with the r

89 s-sectional analysis of associations between toenail metals and BP among older men from the Normative

90 re strengthened in models adjusted for other toenail metals.

91 In conclusion, the toenail nicotine biomarker was found to be a strong pred

92 Mean toenail nicotine level among cases was 0.95 ng/mg compar

93 is US study was to assess the association of toenail nicotine level as a novel biomarker with lung ca

94 r for the highest versus lowest quintiles of toenail nicotine level was 10.50 (95% confidence interva

95 dose-response association between increasing toenail nicotine levels and risk of CHD (p(trend) < 0.00

96 In conclusion, toenail nicotine levels are predictive of CHD among wome

97 The authors assess the ability of toenail nicotine levels as a biomarker to predict incide

98 multivariate analyses, the relative risk for toenail nicotine levels in the highest quintile was stil

99 se in the log-transformed unit of continuous toenail nicotine levels, there was a 42% increase in the

100 /(238)U ratios in the hair, fingernails, and toenails of occupationally exposed workers and control v

101 often assessed in epidemiologic studies, and toenails offer a convenient alternative to serum because

102 was to compare iron measures using serum and toenails on both a cross-sectional and longitudinal basi

103 en identified in United States patients with toenail onychomycosis.

104 ach case on age, smoking status, and date of toenail return was chosen.

105 he association between 17 metals measured in toenail samples and leukocyte relative telomere length (

106 Toenail samples collected in 1987 were analyzed for nico

107 d method for analyzing trace metal(loid)s in toenail samples from three populations (n = 97) near the

108 a total of 540 controls were interviewed and toenail samples of sufficient weight were collected from

109 Our data suggest that toenail samples provide a useful biologic marker for qua

110 Toenail samples provide an integrated measure of interna

111 Arsenic determinations were made from toenail samples using neutron activation analysis.

112 Toenail samples were collected in 1987, and selenium con

113 Arsenic levels in toenail samples were determined by using neutron activat

114 comprehensive smoking history, and submitted toenail samples, from which we measured selenium levels.

115 detected in almost all hair, fingernail, and toenail samples.

116 were observed between placenta and maternal toenail Se (beta = 63.49; P < 0.0001) and Pb (beta = 0.9

117 We performed a GW meta-analysis of toenail Se concentrations, which reflect a longer durati

118 xplained approximately 1% of the variance in toenail Se concentrations.

119 Toenail Se was measured using neutron activation analysi

120 ity studies included in the meta-analysis of toenail selenium and cancer risk indicated a reduction i

121 This study found no associations between toenail selenium and inflammation as measured by fibrino

122 timated RR: 0.29; 95% CI: 0.14, 0.61) with a toenail selenium concentration between 0.85 and 0.94 mug

123 case-control studies) that measured blood or toenail selenium concentrations and 6 randomized trials

124 Comparing the highest quintile of toenail selenium level with the lowest, odds ratios for

125 Toenail selenium levels analyzed by neutron activation w

126 atistically significant associations between toenail selenium levels and any of the 3 inflammatory bi

127 igated prospectively the association between toenail selenium levels and risk of coronary heart disea

128 The authors examined the associations of toenail selenium levels with blood concentrations of fib

129 ppeared to modify the effects of alcohol and toenail selenium on melanoma risk.

130 selenium intake or status (plasma, serum, or toenail selenium), assessments of prostate cancer cases

131 w insights into the speciation of arsenic in toenails, the microdistribution of trace elements, and t

132 c, and PC-K16; (2) concurrent fingernail and toenail thickening in PC-K6a and PC-K17; (3) more palmar

133 Toenail was the best bio-indicator of intake for the mos

134 confirmed a hierarchic scale where 'Cutting toenails' was the first item with which participants had

135 toenails and the speciation of As in situ in toenails were investigated using synchrotron X-ray fluor

136 5 mug/g) vs. low-level (39.5-116.2 mug/g) of toenail zinc had a statistically significant positive as

137 Toenail zinc levels are reliable biomarkers of a relativ

138 paring the highest to the lowest quartile of toenail zinc levels was 1.21 (95% CI: 0.90-1.63; Ptrend

139 Toenail zinc levels were measured with an inductively-co