ライフサイエンスコーパス: tolerance

1 ion, consistent with a role in acute disease tolerance.

2 anti-alpha-klotho antibody impaired glucose tolerance.

3 s required and display good functional group tolerance.

4 rate responses to SAHC, thereby promoting g-tolerance.

5 with a broad scope and high functional group tolerance.

6 vascular responses, cerebral perfusion and g-tolerance.

7 underlie individual variation in shift work tolerance.

8 rmining immune responses such as allergy and tolerance.

9 s, and help to reveal the traits that confer tolerance.

10 slightly attenuated BMDC-induced immunogenic tolerance.

11 lso act in bacterial immunity and antibiotic tolerance.

12 e to good yields, with good functional group tolerance.

13 ization by CMV-mediated disruption of stable tolerance.

14 interfaces, enabling further improved damage tolerance.

15 ility (S genes) can help achieve sustainable tolerance.

16 ove certain agronomic traits such as lodging tolerance.

17 ict motor unit activation and limit exercise tolerance.

18 d strain-specific differences in spontaneous tolerance.

19 ho-physiological traits related with drought tolerance.

20 pressed BCL2L11, expression and promoted TKI tolerance.

21 ate maintenance of quiescence and peripheral tolerance.

22 ear translocation, suggesting a mechanism of tolerance.

23 urable binding with CO, contribute to its CO tolerance.

24 seems to be important in established peanut tolerance.

25 s important for the maintenance of allograft tolerance.

26 k, early blooming in winter, and strong cold tolerance.

27 ating its broad utility and functional group tolerance.

28 nd physiological traits associated with salt tolerance.

29 thin regulatory modules associated with heat tolerance.

30 de substrate scope and good functional group tolerance.

31 erapy in LTRs and achieved > 50% operational tolerance.

32 h reduced systolic augmentation and exercise tolerance.

33 aemoglobin affinity impacts hypoxic exercise tolerance.

34 se of allergic disease and induces long-term tolerance.

35 eases in murine models by inducing bystander tolerance.

36 of beta-1,4-galactan negatively affects salt tolerance.

37 d to strike a balance between protection and tolerance.

38 d, rather than reduced, MOR signaling caused tolerance.

39 a role for PrimPol in HR-mediated DNA damage tolerance.

40 in insulin action to maintain normal glucose tolerance.

41 ict motor unit activation and limit exercise tolerance.

42 and positive roles of PTPN in plant drought tolerance.

43 hat sustained MOR signaling caused analgesic tolerance.

44 ransgenic plants displayed enhanced freezing tolerance.

45 d scope, and show excellent functional group tolerance.

46 e existence of a hard limit in upper thermal tolerance.

47 nd may also impact biotic and abiotic stress tolerance.

48 with diabetes and 133 with a normal glucose tolerance.

49 n in directing distinct mechanisms of T cell tolerance.

50 Aire), a critical mediator of central immune tolerance.

51 highest for known MIECs, but also high CO(2) tolerance.

52 ce availability rather than absolute thermal tolerances.

53 gin to exceed species' historically observed tolerances.

54 r description of the interdependence between tolerances.

55 se changes depends on their inherent thermal tolerance, acclimation capacity, and ability for evoluti

56 is is the first instance of true operational tolerance after complete cessation of immunosuppression.

57 was required to maintain long-term clinical tolerance after peanut OIT.

58 biosis with beneficial bacteria and provides tolerance against a combination of abiotic (nutrient dep

59 With good functional-group tolerance, alkyl and benzyl amine derived PDIs (incl. co

60 This localization offers flaw tolerance, allowing ductility to win over fracture.

61 her plasticity in the form of inducible warm tolerance also evolved.

62 To evaluate the genetic variation of salt tolerance among cotton species, 17 diverse accessions of

63 critical roles of the RAFs in osmotic stress tolerance and ABA responses as well as in growth and dev

64 ine an efficient strategy for screening heat tolerance and accentuate the need to focus on reduced ra

65 of breast-feeding in the development of oral tolerance and allergic diseases is controversial, which

66 neral principles, such as breaches in immune tolerance and barriers, leading to the promotion of immu

67 with these drugs leads to the development of tolerance and can lead to opioid use disorder.

68 tion and epigenetic control affects EGFR-TKI tolerance and cancer dissemination.

69 We also discuss evidence of tolerance and current knowledge on its genetic regulatio

70 L4 loss-of-function increases osmotic stress tolerance and decreases sensitivity to cytokinin-induced

71 ve translation mechanisms involved in stress tolerance and drug resistance.

72 OsCADT1 mutation increases Cd tolerance and enriches selenium in rice grains, providin

73 punishment-resistant responding, food reward tolerance and escalation of intake through 24-h energy i

74 ectrolyte leakage to determine leaf freezing tolerance and expression analyses of cold-responsive gen

75 s of the species' range to correlate thermal tolerance and gene expression among populations from dif

76 Cassava is cultivated due to its drought tolerance and high carbohydrate-containing storage roots

77 urfaces or the host immune system to restore tolerance and homeostasis will be explored.

78 hma by modulating the balance between immune tolerance and inflammation.

79 Mice lacking TrkB.T1 show impaired glucose tolerance and insulin secretion.

80 from diet-induced obesity, improving glucose tolerance and insulin sensitivity with reduced systemic

81 Because of its remarkable stress tolerance and intense flavor, SP has been used as an imp

82 y T cells (T(regs)) maintain peripheral self-tolerance and limit immune mediated pathology.

83 d for higher FOXP3(+) T-cell-mediated immune tolerance and lower CD8(+) T-cell-mediated cytotoxicity.

84 cal evidence of the trade-off between stress tolerance and organism fitness is scarce and blurred by

85 posure to PM2.5 impaired glucose and insulin tolerance and reduced energy expenditure and 18FDG-PET u

86 ice displayed significantly impaired glucose tolerance and reduced insulin sensitivity when maintaine

87 ng growth promotion, nutrient uptake, stress tolerance and resistance to pathogens.

88 low-affinity Pi transporter that mediates UV tolerance and rice yields at different latitudes.

89 rtin cattle in the understanding of acquired tolerance and transplant immunology represents generatio

90 tasis and models of weak activation, such as tolerance and tumor models.

91 on method, allowing optimization of the mass tolerances and other key search parameters.

92 ly extensive database on plant heat and cold tolerances and used this dataset to test for thermal mac

93 d substrate scope, has high functional-group tolerance, and can be employed for the late-stage functi

94 s, which have associated risks of addiction, tolerance, and dependence, for the management of acute a

95 icient to increase running distance, glucose tolerance, and mitochondrial activity similar to the eff

96 ad substrate scope and good functional group tolerance, and the in situ-generated HCN bypasses the us

97 in immune system in our porcine model of VCA tolerance, and the kinetics of cutaneous chimerism in bo

98 These include immune-, heat-tolerance- and reproduction-related genes.

99 show that when dispersal ability and climate tolerance are restricted, microclimatic variation over d

100 alarming if we are to understand how thermal tolerances are distributed globally, improve predictions

101 ath requires the knowledge of radiation dose tolerance at very small tissue volume.

102 ype bacterial populations exhibit antibiotic tolerance, bacterial mutants with higher or lower tolera

103 leep conditions, we tested cold pressor pain tolerance before and 40-min after double-blind injection

104 n LTRs withdrawn from SRL and if blood/graft tolerance biomarkers were predictive of successful withd

105 Mammals achieve immunological tolerance by down-regulating both major histocompatibili

106 active B cells contribute to transplantation tolerance by foregoing germinal center responses while r

107 Agonistic VISTA engagement increased T cell tolerance by promoting antigen-induced peripheral T cell

108 ors BPC1/BPC2 positively regulate plant salt tolerance by repressing GALS1 expression and beta-1,4-ga

109 f mice which differ in adiposity and glucose tolerance, C57BL/6J and WSB/EiJ.

110 Additionally, we find that larval tolerance can explain large-scale biogeographic patterns

111 (N = 973) with different weight and glucose tolerance categories were recruited.

112 1 but not of mCyp c 1 induced long-term oral tolerance, characterized by lack of parvalbumin-specific

113 etworks that control the six main peripheral tolerance checkpoints throughout the life of a T cell: q

114 desiccation, and how vegetative desiccation tolerance circumvents destructive, stress-induced cell s

115 among these factors was quantified using the tolerance coefficient (TC) and variance inflation factor

116 mber of dimensions needed to summarise their tolerance combinations, and the best trade-off model amo

117 Secondary objectives included tolerance, compliance to oral supplementation, chemother

118 Clusters associated with improved drought tolerance consisted of phene states that likely enable g

119 quencing and transcriptomics, we showed that tolerance could be attributed to disruption of one of tw

120 Our aim was to determine if operational tolerance could be observed in LTRs withdrawn from SRL a

121 However, untoward side effects such as tolerance, dependence, respiratory suppression, constipa

122 -knockin) mice demonstrated improved glucose tolerance, despite impaired insulin sensitivity and enha

123 ressing lines also showed increased salinity tolerance due to reduced salinity uptake and dilution of

124 elial cell axis regulates intestinal disease tolerance during experimental colitis.

125 ndant autoantibodies, suggesting that B cell tolerance during gestation is not yet fully established.

126 a) disruption of established transplantation tolerance during tolerance maintenance; and (b) the poss

127 performance in both BEEP and Enquiring About Tolerance (EAT) study participants who did undergo OFC.

128 ealed mechanism of biotic and abiotic stress tolerance, energy conservation and photoperiod responsiv

129 role of ABI3 in seed maturation, desiccation tolerance, entry into a quiescent state and longevity.

130 lammonium (EA) cations which lie outside the tolerance factor range can still enter the cages of the

131 ure remain mysterious, especially since many tolerance-factor-based approaches predict CsPbI(3) shoul

132 mu/t, where mu and t are the octahedral and tolerance factors, respectively, is identified, which ac

133 d a host response outcome with immunological tolerance features.

134 For immunomodulation toward tolerance, food compounds could be chemically modified,

135 ble on shade, drought, waterlogging and cold tolerance for 799 northern hemisphere woody species, we

136 at the hematopoietic system has a remarkable tolerance for major disruptions in chromatin structure a

137 erobic nature of eubacterial cells with poor tolerance for oxygen.

138 bject for awake scanning given their natural tolerance for restraint.

139 Scope, tolerance for these transition-metal-free C-H/C-Li coupl

140 Distinguishing tolerance from resistance might provide important insigh

141 the most valuable sources of resistance and tolerance genes for citrus.

142 Remarkable functional group tolerance has also been demonstrated.

143 Although operational tolerance has been achieved in liver and kidney transpla

144 mperatures that exceed historically observed tolerances help explain widespread bumble bee species de

145 vironmentally relevant traits (e.g., drought tolerance); however, incorporating high-dimensional phen

146 t a strong phylogenetic signal towards urban tolerance; however, they have largely been ignored in ur

147 ng killing may decrease poaching incidence ('tolerance hunting') or increase it ('facilitated poachin

148 ed substrates and is involved in desiccation tolerance, implying that CsrA controls key functions inv

149 ge multi-epitope protein capable of inducing tolerance in a heterogeneous (in terms of HLA status) po

150 orbidities, will assist recovery of exercise tolerance in a variety of conditions that limit quality

151 by 3-17% and significantly improved glucose tolerance in aged mice fed a chow (~30% vs. saline) or H

152 he therapeutic induction of antigen-specific tolerance in autoimmune diseases.

153 d untreated plants indicates substantial BPA tolerance in both varieties.

154 e two genotypes revealed higher and integral tolerance in C-76 through activation of key genes involv

155 able genetic resource for improving salinity tolerance in commercial tomatoes.

156 Antibody injection improved glucose tolerance in D734A INSR-expressing mice and reduced hype

157 s that are essential for development of oral tolerance in early life and demonstrate the importance o

158 egulate immune homeostasis to promote immune tolerance in patients with autoimmune diseases, includin

159 development of plants, but also in inducing tolerance in plants against various environmental extrem

160 cular mechanism of indole-induced antibiotic tolerance in Pseudomonas species and had important impli

161 l roles of OsJAZ9 for improving K deficiency tolerance in rice by altering JA levels and JA responses

162 a forward genetic approach to investigate Cd tolerance in rice.

163 reduced rates of respiration to improve heat tolerance in rice.

164 ow that respiratory burst induces antibiotic tolerance in the spleen during a murine systemic infecti

165 in CP4 (CP4 EPSPS), which confers glyphosate tolerance in transgenic crops.

166 and capitalized on extraordinary desiccation tolerance in two of the species, contrasting with desicc

167 in adult beta-cells display improved glucose tolerance, increased glucose-stimulated insulin secretio

168 les and was associated with improved glucose tolerance, increased metabolism, energy expenditure, and

169 knockdown of ZmPTPN inhibited plant drought tolerance, indicating conserved and positive roles of PT

170 These data clarify the immune regulatory and tolerance-inducing effect of alcohol consumption.

171 The underlying mechanism for this tolerance-inducing effect of alcohol, however, is unknow

172 upt gut immune homeostasis and prevents oral tolerance induction to bystander food antigen through th

173 d gene expression signatures associated with tolerance induction.

174 del of bone marrow transplantation (BMT) for tolerance induction.

175 ing the conceptual changes in the meaning of tolerance inside and outside the field of phytopathology

176 fine balance between immune rejection versus tolerance is achieved with various applied therapies.

177 Among green plants, desiccation tolerance is common in seeds and spores but rare in leav

178 tion of alkynes with a high functional group tolerance is presented.

179 ously tolerant transplant recipients in whom tolerance maintenance is disrupted by an episode of acut

180 established transplantation tolerance during tolerance maintenance; and (b) the possibility of recipi

181 thenia gravis, although disrupted peripheral tolerance may play a greater role in autoimmunity develo

182 r their usability for forecasting adult heat tolerance, measured as the vegetative heat tolerance of

183 strate their role in deficit moisture stress tolerance mechanism of horsegram variety Paiyur1 with th

184 Accordingly, either a DPC tolerance mechanism or a DPC repair pathway is essential

185 regulation of AtCYP94B1 is part of the salt tolerance mechanism.

186 physiological, and biochemical bases of salt-tolerance mechanisms.

187 cost of long-term reliance on IL-1-mediated tolerance mechanisms.

188 nnosidase gene directly associated with this tolerance metric.

189 d an allogeneic murine islet transplantation tolerance model to examine the impact of acute CMV infec

190 Our results point to an oxidative stress tolerance network that is important for single cells dur

191 , we present conclusive evidence that opioid tolerance occurs independently of MOR internalization an

192 h 87% given the calibration device threshold tolerance of +/-3%.

193 ait, which is thought to be required for the tolerance of abiotic stress, is not required for high ra

194 t tolerance, measured as the vegetative heat tolerance of adult rice plants through visual (stay-gree

195 ile cleavage of the benzazole auxiliary, and tolerance of amide linkage forming conditions constitute

196 Strategies to improve patients' tolerance of and adherence to statins may enhance the ef

197 ent, the molecular basis of terminal drought tolerance of certain pearl millet genotypes remains elus

198 Amendment of amino acids enhanced arsenic tolerance of D. mccartyi.

199 ethods are limited in their alkene-types and tolerance of electron-rich, readily oxidized functionali

200 arenes and that the Rh catalysis has better tolerance of halogen groups.

201 d much of that increase can be attributed to tolerance of increased planting density(2-4).

202 ile also significantly enhancing the thermal tolerance of its aphid vector Rhopalosiphum padi (by 8 d

203 e animals are under strong selection for the tolerance of low O(2) (hypoxia)(5).

204 otein partials prior to drying, or the lower tolerance of M. inflexa relative to most bryophytes stud

205 esolution of infection, final visual acuity, tolerance of miltefosine, and clinical course of disease

206 In humans, tolerance of others within our space also depends greatl

207 e, while overexpression of SLG1 enhances the tolerance of plants to high temperature.

208 or providing and maintaining peripheral self-tolerance of potentially autoreactive cells.

209 Finally, we show the mutation tolerance of the catalytic residues based on their roles

210 The broad generality and functional group tolerance of this method is extensively examined through

211 In this study, we investigated salinity tolerance of two species of wild tomato endemic to the G

212 changes, but cascading effects of organismal tolerances on the assembly and functioning of reef fish

213 a, to induce mutagenesis that enables stress tolerance or escape.

214 egrated ones), but only in species with more tolerance over food.

215 sts and surgeons exploring immune transplant tolerance owe much to the history of the freemartin, sev

216 ron treatment included improved oral glucose tolerance (P < 0.01), reduced hemoglobin A1c levels (P =

217 mouse, results in compromised central immune tolerance processes that may significantly impact indivi

218 addiction-relevant behaviors, and instead of tolerance, produces psychomotor, incentive, and neural s

219 t on ILC2s significantly ameliorates glucose tolerance, protects against insulin-resistance onset and

220 an enhance seagrass productivity and thermal tolerance, providing some compensation for climate warmi

221 mphocytes, yet how this lineage attains self-tolerance remains unknown.

222 hematosus (SLE) is defined by loss of B cell tolerance, resulting in production of autoantibodies aga

223 Cold tolerance scaled weakly with both dimensions.

224 The tolerance state systemically and locally suppresses the

225 ity and different BMI categories, or glucose tolerance status.

226 that species-specific differences in thermal tolerances strongly influenced occupancy dynamics such t

227 studies thus identify Notch4-mediated immune tolerance subversion as a fundamental mechanism that lic

228 rs of programs which actively train distress tolerance, such as Compassionate Mind Training (CMT), ar

229 ide level in response to a 4-hour mixed-meal tolerance test (4-hour C-peptide AUC) at week 52.

230 ype 1 diabetes classified by peak mixed-meal tolerance test (MMTT) C-peptide as negative (<0.007 pmol

231 lin secretion was measured with a mixed meal tolerance test (MMTT).

232 nd whose mothers had a 2-h 75-g oral-glucose-tolerance test (OGTT) at 26-28 weeks of gestation were i

233 story of T2DM (FH+) received an oral glucose tolerance test and two-step hyperglycemic clamp (100 and

234 posed that plants have broader environmental tolerances than animals but are more sensitive to climat

235 Tregs) are non-redundant mediators of immune tolerance that are critical to prevent autoimmune diseas

236 d climate information and crop specific salt tolerances, the model quantifies the negative implicatio

237 imate change, but depending on their thermal tolerance, they may be particularly vulnerable to enviro

238 approaches to the improvement of crop stress tolerance through optimizing microbial communities.

239 hat protects plants from pathogens, promotes tolerance to abiotic stresses and fortifies cells to wit

240 The acquisition of tolerance to an environmental stressor can result in org

241 cachexia, that is associated with decreased tolerance to antineoplastic therapy, poor prognosis and

242 sion of TMPRSS13 in CRC cell lines increased tolerance to apoptosis-inducing agents, including paclit

243 Besides conferring tolerance to aromatic acids, ESBP6 overexpression was al

244 Agronomic characteristics and tolerance to biotic and abiotic stresses in hexaploid wh

245 ato chips of cultivars with varied levels of tolerance to cold during storage at 6 and 13 degrees C.

246 ological mechanisms underpinning multistress tolerance to desiccation and freezing, we conducted an e

247 rom drier summers had traits conferring more tolerance to drought such as small sclerophyllous leaves

248 -supplemented diet showed slightly increased tolerance to DSS-induced experimental colitis, as judged

249 rsely affecting the capacity to develop oral tolerance to food antigen in early life.

250 nferring flowering competence, favors a high tolerance to freezing and the development of a winter-ha

251 cellular oxygen consumption rate and greater tolerance to glucose challenge in mice.

252 high glycogen storage level showed increased tolerance to glucose deficiency among the studied melano

253 Loss of immune tolerance to gut microflora is inextricably linked to ch

254 The model has good tolerance to image quality and is tested with different

255 Tolerance to kidneys, but not thoracic organs or islets,

256 enriched in genes for which humans show poor tolerance to loss of function.

257 rowth over a wide-frequency range, decreased tolerance to loud sounds and reduced behavioral reaction

258 is assumed that newborns may develop immune tolerance to milk-transmitted pathogens similarly to foo

259 r, GRXS17 was specifically involved in plant tolerance to moderate high temperature and protected roo

260 kill phagocytosed S. aureus, but also induce tolerance to multiple antibiotics.

261 of those fruits can possibly confer enhanced tolerance to postharvest abiotic stresses.

262 ler 2 (vic2), that abrogates neonatal immune tolerance to retroviruses.

263 The Galapagos tomatoes displayed greater tolerance to salt stress than the commercial lines and s

264 esponse to foreign antigens vs. induction of tolerance to self-antigens.

265 landraces of rice possess variable levels of tolerance to submergence stress, but gene discovery and

266 major histocompatibility class I can enhance tolerance to subsequent skin allografts through indirect

267 rray of genetic tools for acquiring enhanced tolerance to such metals.

268 homeostasis in their nutrient pools, showing tolerance to the different nutrient regimes.

269 ty to alcohol-induced sedation and developed tolerance to the sedation after repeated alcohol adminis

270 ow tropical species may develop an increased tolerance to these stressors and the cost of adaptations

271 g behavior, evasion of plant defenses, plant tolerance to utilization, and sources of insect and micr

272 ruses provide a genomic record of historical tolerance to viral infection in bats.

273 ne structures, exhibit surprising structural tolerance to, and excellent miscibility with, commonly u

274 and, finally, chemical efflux and antibiotic tolerance (TolC efflux pump and AadA aminoglycoside 3-ad

275 -adapted viruses also exhibited an increased tolerance toward disinfection by free chlorine.

276 biogeographic distribution of the dominance-tolerance trade-off across North America, we approximate

277 ariability exists in rice germplasm for salt tolerance traits.

278 ned neoantigens in the context of peripheral tolerance, transplantation, autoimmune diseases and canc

279 ansgenics indicate a direct correlation with tolerance under HS conditions.

280 ied with 40-320 muM selenate showed complete tolerance up to 160 muM and accumulated up to 1300 mg of

281 indicate that AKR2A is involved in chilling tolerance via an interaction with KCS1 to affect VLCFA b

282 letion rate and adherence were good, and the tolerance was acceptable; no seroconversion was observed

283 Selection to increase upper thermal tolerance was also performed on warm-acclimated fish to

284 g, insulin sensitivity, and systemic glucose tolerance was consistent with functional MRI data in hum

285 he Fourth International Workshop on Clinical Tolerance was held in Pittsburgh, Pennsylvania, Septembe

286 By contrast, glucose tolerance was mildly impaired in mice lacking PAK2 speci

287 In addition, a very good functional group tolerance was observed in these reactions.

288 which evolution toward higher upper thermal tolerance was slow (0.04 +/- 0.008 degrees C per generat

289 ever, within the germinal center, peripheral tolerance was still enforced, and there was selection ag

290 o the chlorpyrifos-induced reduction in heat tolerance was stronger when the pesticide pulse followed

291 egulatory cells (Treg), essential for immune tolerance, was significantly reduced.

292 Two proteins involved in drought tolerance were also identified.

293 of which negatively regulate plant freezing tolerance, were destabilized by cold stress in a phytoch

294 differentiation accompanied by increased TKI tolerance, which can interfere with ectopic SOX2 express

295 , disruption of coronin 1 promotes allograft tolerance while immunity towards a range of pathogenic m

296 lactis subsp cremoris had increased glucose tolerance while on the Western-style diet compared to mi

297 diabetes mellitus and have impaired glucose tolerance whilst cholestatic.

298 reaction shows outstanding functional-group tolerance with respect to both the alpha-ketoacetal and

299 ndirectly expanded nTreg leading to dominant tolerance without additional immunological manipulation.

300 including disease resistance, abiotic stress tolerance, yield, nutritional quality and additional con