ライフサイエンスコーパス: tomogram

1 sing the Fourier transform of the RVFV MP-12 tomogram.

2 ent gated acquisition of the second-day rest tomogram.

3 ordinates of candidate-macromolecules in the tomogram.

4 nuclear pore complex obtained from a single tomogram.

5 tching known structures to the cryo electron tomogram.

6 f 9 subvolumes of the adhesin extracted from tomograms.

7 he perinuclear space as seen in the electron tomograms.

8 oteins, averaged 70-79 trimers per virion in tomograms.

9 ings were verified in the postimplant serial tomograms.

10 g both perfusion and function from perfusion tomograms.

11 site using cross-sectional film-based linear tomograms.

12 those from oblique radiographs and computed tomograms.

13 iginal digitized tomograms and the deblurred tomograms.

14 creasing the SNR of cryoEM images and cryoET tomograms.

15 ation between monomeric and dimeric AuNPs in tomograms.

16 late matching to find molecular complexes in tomograms.

17 ratio, using the knowledge learned from raw tomograms.

18 re local membrane thickness in cryo-electron tomograms.

19 enges in visualization and interpretation of tomograms.

20 icient macromolecule localization method for tomograms.

21 volume and low signal-to-noise ratio of the tomograms.

22 ly relevant information from cryo-soft X-ray tomograms.

23 cquisition and minutes-long 3D ptychographic tomograms.

24 ng, are encoded in three-dimensional (3D) RI tomograms.

25 the residual artifacts in the reconstructed tomograms.

26 pre-discharge and 30-day abdominal computed tomograms.

27 d the resolution and the interpretability of tomograms.

28 g methods for detection of complexes in cell tomograms.

29 step in a visual proteomics analysis of cell tomograms.

30 lassification of complexes inside whole-cell tomograms.

31 aled by visualization and segmentation of 3D tomograms.

32 model fit to a reconstruction from electron tomograms.

33 d layer (LSL) were delineated in 2D sagittal tomograms.

34 occurring protein complexes in cryo electron tomograms.

35 resolution and low signal-to-noise ratio in tomograms.

36 known macromolecular complexes in whole cell tomograms.

37 y unknown protein complexes in cryo electron tomograms.

38 ark the results with 3D template matching of tomograms acquired on identical sample locations and ide

39 hieving a resolution of 54 nm full-pitch and tomogram acquisition times of 30 min to two hours, we va

40 postsynaptic signatures, and the subsequent tomograms allow for the identification of key features o

41 The resulting tomograms allow us to locate regions of efficient cathod

42 applicability using realistically simulated tomograms, allowing for the inclusion of noise and disto

43 The tomograms also document pH-induced changes affecting the

44 workflow readily integrates within existing tomogram analysis pipelines and, when applied across exp

45 advances in cryo-electron tomography and sub-tomogram analysis(2,3) to visualize the structural dynam

46 t and width of the mandible on each original tomogram and each deblurred tomogram in triplicate.

47 dges in lower-resolution electron microscopy tomograms and by "mapping" the functional effects of gen

48 The sagittal tomograms and en face reflectance images over a 2-cm(2)

49 o XRF 2D single-slice tomography data and 3D tomograms and is particularly relevant for, but not limi

50 The visual interpretations of tomograms and polar maps, vessel stenosis from coronary

51 firmed by visual inspection of electron cryo-tomograms and power spectra of single projection views,

52 AQ algorithm segmented the LV BPs on the BP tomograms and subdivided volumes into 17 subregions.

53 ht and width for both the original digitized tomograms and the deblurred tomograms.

54 s characteristic of cryo-electron tomography tomograms and the sheer size of tomographic datasets.

55 We confirmed POAG based on optical coherence tomograms and visual fields.

56 some structure-derived from cryopreserved EM tomograms, and dispersed throughout the nucleus.

57 Crystal structures, cryoelectron tomograms, and interlayer chemistry were consistent with

58 rdiograms with Doppler, myocardial perfusion tomograms, and treadmill exercise or pharmacological tes

59 ll candidate macromolecules cut out from the tomogram are available for download.

60 Tomograms are presented for different realisations of mu

61 Simulated tomograms are then used for assessing the template-free

62 The server accepts tomograms as they are imaged and reconstructed by Cryo-E

63 We calculated a 16 angstrom resolution sub-tomogram average of the matrix protein (M) layer that fo

64 The resulting sub-tomogram average reaches a resolution of ~26 angstrom, l

65 A 9.1- angstrom sub-tomogram-averaged reconstruction of virion-bound Env in

66 Our sub-tomogram averages indicate the positioning of F-trimer p

67 particle asymmetric reconstructions and sub-tomogram averages, with intermediate evidence that can a

68 Here, we use sub-tomogram averaging and AlphaFold, to generate a pseudo-a

69 Sub-tomogram averaging enabled the structural refinement of

70 ure of herpesvirus capsids determined by sub-tomogram averaging from nuclei of eukaryotic cells, achi

71 ayer through electron cryotomography and sub-tomogram averaging of cell stalks.

72 Here, using electron cryo-tomography and sub-tomogram averaging of intact Legionella pneumophila, Pse

73 ryo-ET resolution either by some form of sub-tomogram averaging or template matching, respectively pr

74 Here, we used a segmented sub-tomogram averaging strategy to reassess this paradigm an

75 Here we use cryo-electron tomography and sub-tomogram averaging to derive the intact structure of the

76 own, we use cryo-electron tomography and sub-tomogram averaging to determine the molecular organizati

77 ynamic biological assemblies, we combine sub-tomogram averaging with atomistic molecular dynamics (MD

78 Sub-tomogram averaging yields a resolution of 21.8 angstrom

79 rety or as individual tiles suitable for sub-tomogram averaging, enabling efficient data processing a

80 Without the need for sub-tomogram averaging, IsoNet generates tomograms with sign

81 Using sub-tomogram averaging, we elucidate features of the low pH-

82 Combining cryo-ET and sub-tomogram averaging, we show the in situ architectures of

83 oriented complexes of the same kind for sub-tomogram averaging.

84 rpretation of cellular tomograms without sub-tomogram averaging.

85 otomography and sub-nanometre-resolution sub-tomogram averaging.

86 -throughput cryo-electron tomography and sub-tomogram averaging.

87 obtained by cryo-electron tomography and sub-tomogram averaging.

88 In tomograms, CaMKII holoenzymes can be visualized directly

89 Tomograms can be averaged when display of only the regul

90 potential, we show that 3D refractive index tomograms can capture subtle morphological differences a

91 The different time frames of tomograms constitute a movie of the object in motion, th

92 Tomograms constructed from fixed, cryosectioned cells re

93 This task becomes challenging when tomograms contain mixtures of unknown complexes extracte

94 A whole cell cryo electron tomogram contains structural information of all its macr

95 tion in electrical conductivity shown in the tomograms correlate well with diesel removal from the sa

96 Here, we recorded cryo-electron tomograms (cryo-ET) in which individual cadherins can be

97 ogram averages calculated from cryo-electron tomograms (cryo-ET) of crowded cellular environments is

98 We show that amalgamation of computed tomogram (CT) data with clinical parameters (CP) in gene

99 Recent studies using chest computed tomograms (CTs) in smokers and in the general population

100 a series of 6 to 11 apical echocardiographic tomograms, depending on heart rate, in 11 patients.

101 a bracelet-like ring structure for which 4D tomograms display different modes of motion, such as bre

102 The tomograms distinguish two kinds of glycoprotein spikes [

103 It is shown that the tomograms do not represent the physical structures prese

104 lls and molecular specificity within cryo-ET tomograms, ExoSloNano expands the proteome available to

105 Tomograms feature complex data with densities of diverse

106 We provided a sequence-specific cryo-ET tomogram fitting of DNA minicircles, registering the seq

107 er, preparing extensively annotated cellular tomograms for training macromolecule localization method

108 cross-bridges through the three-dimensional tomogram from their origins on 14.5-nm-spaced shelves al

109 dentification of individual molecules within tomograms from cryoET is challenging because of sample c

110 e, we achieve high quality energy-dispersive tomograms from low dose, noisy datasets using a dedicate

111 d model that infers multiple 3D fluorescence tomograms from RI measurements of the corresponding subc

112 ubcellular features in 120 platelet electron tomograms from these two groups showed statistically sig

113 The tomograms further reveal that full-sized spherules conta

114 Through subtomogram averaging and subsequent tomogram-guided sub-particle reconstruction, we determin

115 m 99mTc-sestamibi myocardial perfusion gated tomograms have demonstrated a high degree of accuracy an

116 nsmission Electron Tomography, the resulting tomograms have excellent (de-)focus and alignment proper

117 -0.58 +/- 1.36 mm) compared to the deblurred tomograms (height: -0.58 +/- 1.16 mm; width: 0.37 +/- 0.

118 ogether, to obtain a simulated cryo-electron tomogram image with deformable structures.

119 amework for simulating crowded cryo-electron tomogram images including non-deformable macromolecular

120 This enables users to simulate cryo-electron tomogram images with non-deformable macromolecular compl

121 We present an interpretation of the tomogram in terms of the packing arrangement of Tsr usin

122 on each original tomogram and each deblurred tomogram in triplicate.

123 s for realistically simulating cryo electron tomograms including noise and image distortions due to t

124 sually handled by segmenting the constituent tomograms independently through time with 3D convolution

125 Qualitative inspections of the tomograms indicate significant morphological differences

126 Moreover, the tomograms indicated that the fibrils extract lipid from

127 ryoEM community for improving micrograph and tomogram interpretability and accelerating analysis.

128 Automated software transformed cinematic tomograms into images demonstrating uniform appearance o

129 n in less than 10 minutes and a high-quality tomogram is available within 30 minutes.

130 cryo-electron tomography (cryo-ET) images or tomograms is crucial for determining their in situ struc

131 high-resolution signal preserved in the raw tomograms is currently limited by a number of technical

132 The pattern emerging in the resulting tomograms is interpreted with recent data on the viscosi

133 ing of macromolecular complexes found within tomograms is known as subtomogram averaging, and this te

134 alization of macromolecules in cryo-electron tomograms is one of the key procedures to unravel struct

135 plex tens of illumination angles in a single tomogram, markedly increasing the volumetric imaging rat

136 the intestine of a dogfish shark, based on a tomogram of a biological sample.

137 In IGS, the surgeon may see any angled tomogram of the patient's body, or 3D anatomies beyond t

138 derately imaged by the inverted conductivity tomogram of the reactor.

139 Unaveraged three-dimensional tomograms of "glycol-stiff" sarcomeres show crossbridges

140 Presurgical conventional tomograms of 23 single-implant sites were analyzed retro

141 ransport at the pore scale, built upon X-ray tomograms of a porous medium at different degrees of liq

142 Furthermore, simulated tomograms of a ziggurat-shaped scatterer and of dentin s

143 Images and tomograms of A/Aichi/68 X-31 virions show the generality

144 ients of an ESCRT cargo protein and electron tomograms of Arabidopsis thaliana endosomes to measure c

145 e that is critical for budding and resembles tomograms of authentic virions.

146 We then establish, using X-ray tomograms of both unpressurised and pressurised arteries

147 Reconstructions of electron tomograms of branch junctions show how Arp2/3 complex an

148 Electron tomograms of capsids attached to or undergoing envelopme

149 ly be good enough to allow interpretation of tomograms of cells, organelles, bacteria and viruses in

150 Here, we present a framework for simulating tomograms of cellular environments at high crowding leve

151 g the procedure to phantom data and electron tomograms of cellular samples significantly improved the

152 rom the statistical analysis of cryoelectron tomograms of cristae vesicles isolated from Drosophila f

153 hods it is crucial to realistically simulate tomograms of crowded cellular environments, which can th

154 -tomograms was used to analyze cryo-electron tomograms of hippocampal synapses.

155 Tomograms of IFM treated with AMPPNP at 23 degrees C rev

156 Tomograms of immature cells suggest models of sheath bio

157 Visualized in cryo-electron tomograms of isolated virions, the tegument was seen to

158 Electron micrographic tomograms of isometrically active insect flight muscle,

159 caveolar membrane profiles were revealed in tomograms of native caveolae inside cells.

160 -band, we have used subtomogram averaging of tomograms of rat cardiac muscle in which subtomograms ar

161 his issue, we have scrutinized cryo-electron tomograms of rat hippocampal neurons for the occurrence

162 Tomograms of rigor IFM show double-headed lead and singl

163 Comparison of in situ crossbridges in tomograms of rigor with atomic model of acto-S1, the com

164 the RV capsid protein with the cryoelectron tomograms of RV particles established a low-resolution s

165 isting FDTD algorithm by comparing simulated tomograms of single and multiple cylindrical scatterers

166 Docking an actoS1 atomic model into EM tomograms of swollen rigor fibers identifies in situ for

167 Both methods leverage cryo-electron tomograms of ternary membranes under vitrified, hydrated

168 3D electron tomograms of the caveolar coat, labeled using cavin-Mini

169 Single-tilt tomograms of the dyads in rat ventricular myocytes indic

170 ing to generate a dataset of 1,829 annotated tomograms of the green alga Chlamydomonas reinhardtii, w

171 Tomograms of the renal parenchyma reconstructed in three

172 s , which are then back-projected to compute tomograms of the sample.

173 By comparing tomograms of wild type and knockout desmosomes, we have

174 lexes, in tens of thousands of electron cryo-tomograms of ~90 bacterial species that we have collecte

175 chnique that is used to produce 3D pictures (tomograms) of complex objects such as asymmetric viruses

176 lating regions or particles of interest from tomograms, organizing them into related groups, and rend

177 ents using biorealistic models guided by our tomograms predict that clustering AMPARs within PSD nano

178 Our tomograms provide insights into the molecular forces tha

179 Cryo-electron tomograms provide the cell geometry and ribosome distrib

180 ening performance significantly improved the tomogram quality.

181 present a method to correct aberrations in a tomogram rather than the beam of a broadband optical int

182 of the limited tilt range; consequently, the tomograms reconstructed using these methods are distorte

183 e the initial modeling based on the electron tomogram reconstruction may be suboptimal.

184 ment, contrast transfer function estimation, tomogram reconstruction, particle picking, high-resoluti

185 To obtain a satisfiable tomogram reconstruction, several key processes are invol

186 idated with transmission electron microscope tomogram reconstructions of the target regions.

187 Using tomograms recorded on cryogenically prepared leaves of A

188 The quality of the tomograms recorded with the Volta phase plate enabled a

189 alternative methods in full and undersampled tomogram recovery, but with less significant performance

190 st majority of molecular species in cellular tomograms remains prohibitively difficult.

191 The tomograms reveal a complex network of spectrin filaments

192 The reconstructed tomograms reveal that early during sporulation, the chro

193 Such tomograms reveal that the inner membrane self-assembles

194 The tomograms reveal the global distribution of GPC, matrix

195 g a cluster of 136 tau filaments in a single tomogram revealed the polypeptide backbone conformation

196 +) spark mass relative to control, while the tomograms revealed both proteins shifted the tetramers i

197 These tomograms revealed structures within the Golgi cisternae

198 l comparisons of individual particles in the tomograms revealed that a majority of the complexes have

199 Preimplant spiral tomograms revealed that the initial prosthetic trajector

200 osin subfragment 1 atomic structure into the tomogram reveals that 90 degrees target zone bridges sha

201 gned molecular subvolumes extracted from the tomogram reveals that the vast majority of molecules sho

202 agnetic resonance imaging, positron emission tomogram scan and connectivity studies in anesthesia and

203 catheterization (77%), followed by computed tomogram scans (52%), mostly body examinations.

204 ion that included chest radiograph, computed tomogram scans, radionuclide imaging, diagnostic cardiac

205 Here, we present Ais: a dedicated tomogram segmentation package that is geared towards bot

206 ware for accurate as well as high-throughput tomogram segmentation.

207 Its application to high-resolution cellular tomograms should also help identify differently oriented

208 3D tomograms show that the spatial arrangement of crumples

209 Cryo-electron tomograms show that tubes span the periplasmic space and

210 Moreover, our tomograms show the organelle interactome of growing auto

211 A computerized tomogram showed a ring-enhancing hypodense lesion in the

212 Tomograms showed an increased concentration of Ca in bot

213 In addition, the tomograms showed distortions in the apical region.

214 Cryo-electron tomogram simulation is an effective solution to test and

215 rties to obtain more realistic cryo-electron tomogram simulation.

216 y for 60 degrees samples of 11-13 short-axis tomograms spanning the entire heart, from which regional

217 d severely changed in averaged cryo-electron tomograms, suggesting that NDK5 is crucial for the intac

218 fast (short-duration) transmission computed tomogram (TCT), acquired immediately before or after the

219 lized by crystal structures and cryoelectron tomograms, the critical gp41-interactive region of gp120

220 For 4D time-series tomograms, this is usually handled by segmenting the con

221 ET method for localizing objects within cryo-tomograms to beyond the diffraction limit of the light m

222 onents, and use ligand-oriented cryoelectron tomograms to define component mobility in the viral spik

223 study retrospectively analyzed conventional tomograms to estimate the prognostic value of the cross-

224 The tomograms unambiguously reveal the coexistence of the tw

225 showed perfusion defects on the post-stress tomogram underwent gated acquisition of the second-day r

226 ) acquisition technique that collects apical tomograms using a continuously internally rotating trans

227 s at the macula were quantified by analyzing tomograms using ImageJ.

228 The data set of eight tomograms was digitized and the blur reduced with the de

229 plate-free classification of oversampled sub-tomograms was used to analyze cryo-electron tomograms of

230 e magnetic catheter, guided by a 3D computed tomogram, was successfully navigated to all pulmonary ve

231 From the tomograms, we measured the surface areas of cores and, h

232 s scaling analysis on ChromSTEM mass density tomograms, we observed that chromatin forms spatially we

233 From electron tomograms, we provided evidence that nontubular VWF is a

234 The tomograms were compared with a control cohort (n = 60).

235 ular horizontal and vertical long axis gated tomograms were generated for 116 studies chosen on the b

236 Foveal tomograms were graded using our 6-point grading system f

237 The electron beam computed tomograms were interpreted by a cardiologist with no kno

238 The conventional stress and rest tomograms were interpreted first by means of a 14-segmen

239 ferences in visual acuity, optical coherence tomograms were recorded in some patients to visualize ce

240 We demonstrate in the domain of time series tomograms which are typically undersampled to allow more

241 eter-free reconstruction method for ion beam tomograms with high accuracy is developed for low-densit

242 for sub-tomogram averaging, IsoNet generates tomograms with significantly reduced resolution anisotro

243 y identifies individual protein complexes in tomograms without relying on metal clusters.

244 nables functional interpretation of cellular tomograms without sub-tomogram averaging.