ライフサイエンスコーパス: tone

1 neurons in the airways control bronchomotor tone.

2 nt that ultimately affects renal vasculature tone.

3 sthesis that approximates the patient's skin tone.

4 e the response of A1 neurons to a subsequent tone.

5 plitude and frequency, but not the lymphatic tone.

6 ongside a hovering high-pitched whistle-like tone.

7 ith reduced discriminability of the exposure tone.

8 drug targets for regulation of smooth muscle tone.

9 d inhibiting Na-H exchangers and sympathetic tone.

10 cter (IAS) generates phasic contractions and tone.

11 protein-coupled receptors to regulate airway tone.

12 ion, indicating a gradual reduction in vagal tone.

13 is associated with corticostriatal dopamine tone.

14 involved in the regulation of renal vascular tone.

15 I(Na,L) in response to increased adrenergic tone.

16 ed metric of HRV that reflects cardiac vagal tone.

17 nt in the regulation of GABAergic inhibitory tone.

18 Ca(2+) influx, permitted by reduced GABA(B)R tone.

19 rol by 21 days, as did spontaneous vasomotor tone.

20 emerges as major regulator of microvascular tone.

21 ase and regulates NO metabolism and vascular tone.

22 interneurons, and increased endocannabinoid tone.

23 omotor development, in particular low muscle tone.

24 g a role for Akt2 in regulating dopaminergic tone.

25 oment-to-moment basis as subjects heard each tone.

26 al repolarization and regulation of vascular tone.

27 binaural combination for amplitude-modulated tones.

28 h, while the N1 was enhanced by attention to tones.

29 tone pattern from a stochastic background of tones.

30 and take flight when they hear female flight tones.

31 e absence or presence of distractor auditory tones.

32 ural than monaural presentation of modulated tones.

33 activity coded the fundamental frequency of tones.

34 d the spiking of Pyr neurons to a subsequent tone 400 ms later.

35 egulation of heart rate(6), pulmonary artery tone(5,7), sleep/wake cycles(8) and responses to volatil

36 heir antennal hearing organs to faint flight tones [7, 8].

37 iplet-sequence ABA- of non-overlapping brief tones, A and B, is a valued paradigm for studying audito

38 ed decrease in internal anal sphincter (IAS) tone (AADI) is a major contributor in the rectoanal inco

39 nctions such as breathing and cardiovascular tone accordingly.

40 de (PYR), aiming to increase parasympathetic tone after MI.

41 present experimentally testable ERB-based CR tone alignment strategies and explain how to use the ERB

42 ERB widening and ERB overlaps and gaps of CR tone alignments.

43 smooth muscle Na/K ATPase modulates vascular tone and blood pressure (BP), the role of its accessory

44 erived hydroperoxide that regulates vascular tone and blood pressure under inflammatory conditions.

45 hosphorylation in the regulation of vascular tone and BP and suggest a novel mechanism, and therapeut

46 ry responses to restore cerebellar GABAergic tone and cerebellar cortical inhibitory efficacy.

47 r acquisition nor recall of fear memories to tone and context were altered after removal of MLI-media

48 data show that GPRC5B regulates vascular SMC tone and differentiation by negatively regulating IP sig

49 t atrium led to dramatic changes in vascular tone and diminution of the VSMC layer with attenuated co

50 ols to correct pathophysiological functional tone and enable personalized medicine when a causative t

51 ontrast, most CA1 neurons did not respond to tone and foot shock throughout the training and recall c

52 at over-activation of sgACC/25 reduces vagal tone and heart rate variability, alters cortisol dynamic

53 nerves are important regulators of vascular tone and hence blood pressure and blood flow.

54 ng potency of CFH, increasing basal vascular tone and impairing tissue perfusion.

55 play a role in setting the spinal inhibitory tone and influencing sensory signaling, as spillover of

56 sensors dictate the blood and tissue immune tone and link dietary habits to inflammatory disease out

57 eptor homolog on motor axons, setting muscle tone and movement vigor.

58 or coordination, respiratory control, muscle tone and pain processing.

59 Muscle tone and power as well as functional ambulatory category

60 e retinal TS increased its contractility and tone and raised the intravascular pressure in the upstre

61 tudies determined a decreased basal detrusor tone and reduced amplitude of nerve-mediated contraction

62 rdiovascular physiology, regulating vascular tone and smooth-muscle cell phenotype.

63 vealed mild bilateral ptosis, reduced muscle tone and strength that worsened in proximal leg muscles,

64 sted the association between parasympathetic tone and the regional brain nAChR availability, as measu

65 The depression of cardio-vagal tone and the shift toward a sympathetic predominance obs

66 Acid-base conditions modify artery tone and tissue perfusion but the involved vascular-sens

67 modynamic instability by decreasing vascular tone and venous return.

68 ld manifest evidence of elevated sympathetic tone and would be associated with lower clinical reasoni

69 city is involved, heightened vasoconstrictor tone and/or responsiveness may also contribute.

70 he mouse primary auditory cortex, using pure tones and broadband dynamic moving ripple stimuli, to ex

71 pared to noise, measured with both synthetic tones and macaque vocalizations.

72 xternally directed attention) or ignored the tones and thought about whatever came to mind (that is,

73 llary), is specialized to regulate vasomotor tone, and functions as a stem/progenitor cell in capilla

74 e with cognition, pathology, and cholinergic tone, and may suggest novel biomarkers and therapeutic t

75 these siblings also displayed reduced muscle tone, and one of them developed recurrent seizure.

76 these siblings also displayed reduced muscle tone, and one of them developed recurrent seizure.On phy

77 FAC, muscle tone, and power showed no association with HKP.

78 an important role in maintaining inhibitory tone, and the expression of this subunit alone is suffic

79 ced to Gaussian noise than to pure frequency tones, and that the activation of BLA-to-FrA axons was t

80 ural than monaural presentation of modulated tones, and when a masker was presented to one ear, it pr

81 d in situ simply via the phases of the drive tones applied to the cavity.

82 mportant for the regulation of cardiac vagal tone are not clear.

83 When two sound tones are delivered to the cochlea simultaneously, they

84 hway.SIGNIFICANCE STATEMENT Harmonic complex tones are ubiquitous in speech and music and produce str

85 male mosquitoes can hear the female's flight tone at surprisingly long distances-from several meters

86 evaluated as vector strength in response to tones at best frequency, and by constructing shuffled an

87 Visual acuity and pure tone audiograms are not suitable outcome measures.

88 Pure tone audiograms are used to assess the degree and underl

89 orbetapir positron emission tomography, pure tone audiometry and cognitive testing as part of a neuro

90 A negative association between pure tone audiometry and mini-mental state examination score

91 hearing sensitivities were assessed by pure-tone audiometry at 19 US sites.

92 Pure tone audiometry performance did not predict concurrent b

93 the analysis was to investigate whether pure tone audiometry performance predicted a range of cogniti

94 There was some evidence that poorer pure tone audiometry performance was associated with lower pr

95 nge of characteristics (including analytical tone, authenticity, clout, three measures of sentiment,

96 ual disability, muscle weakness and abnormal tone, autistic features, behavioral abnormalities, and v

97 res and risk of >=5 dB elevation in the pure-tone average (PTA) of low-frequency (LPTA0.5,1,2 kHz), m

98 of serviceable hearing based on median pure tone averages (PTA), and procedure-related adverse event

99 ting in the optical domain, a continuous two-tone backaction-evading measurement of a localized gigah

100 cortical activity that discriminated between tones became increasingly stable in time as the informat

101 resentation of Gaussian noise (but not 8 kHz tone) between conditioning trials impaired the formation

102 al nerve fibres to modulate neurotransmitter tone, blood flow, adipocyte differentiation and energy e

103 earing loss at 4 weeks of age as measured by tone burst auditory brainstem responses.

104 lar inflammation, oxidative stress, vascular tone, cell proliferation, senescence, mitochondrial func

105 randomly ordered sequences of four low-level tones centered around the frequency of a tone that match

106 effect of motor disruptions on processing of tone changes differed between language groups: disruptio

107 speech motor cortex suppressed responses to tone changes in non-tonal language speakers, whereas dis

108 ch negativity; MMN) responses to phoneme and tone changes in sequences of syllables using electroence

109 speech motor cortex suppressed responses to tone changes in tonal language speakers.

110 of left speech motor cortex on responses to tone changes were inconclusive.

111 nguages, however, processing of pitch (i.e., tone) changes that alter word meaning is left-lateralize

112 t several studies using far-basal suppressor tones claimed that SFOAE components originate many octav

113 teolytic activity and an inflammatory immune tone compared with HC-colonized mice.

114 molecule involved in regulation of vascular tone, compared with aortas from control mice.

115 Infants in the control Consistent Tone condition recognized only the object they had most

116 the same sine-wave tone sequence (Consistent Tone condition).

117 ogma about neurogenic regulation of vascular tone consists of major vasodilatation caused by CGRP (an

118 nly, while keeping the rhythmic structure of tones constant.

119 0 mug/mL) on the following parameters: basal tone, contractions evoked by potassium (KCl 60 mM), acet

120 ons, mice received either paired trials of a tone coterminating with a periorbital shock (conditionin

121 enetic inactivation of PV neurons during one tone counterintuitively decreased the spiking of Pyr neu

122 tory fear discrimination training, where one tone (CS+) was paired with footshock and another tone (C

123 (CS+) was paired with footshock and another tone (CS-) was presented alone.

124 n mice, repeated presentations of sequential tone (CS1) and white noise (CS2) auditory stimuli immedi

125 icted male rats learned to associate a light-tone cue (CS) with water delivery into a port.

126 elf-administration protocol in which a light/tone cue was paired with heroin delivery, followed by 2

127 administration models often include light or tone cues that serve as discriminative stimuli and/or co

128 ty paralleled by increase in parasympathetic tone, delayed hemodynamic decompensation, and improved b

129 tained, or enhanced its response to repeated tones depended on the relative dominance of two differen

130 those in adults when comparing heartbeat and tone detection conditions.

131 with AN damage showed normal thresholds for tone detection in noise (0.1 +/- 1.0 dB compared to cont

132 expectedly impair performance on an adaptive tone discrimination task.

133 7 kHz among distractor tones on an adaptive tone discrimination task.

134 cteria, upon transition to stationary phase, tone down their protein synthesis.

135 Diminished vasomotor tone during the initial stages of regeneration promotes

136 In addition, glycocalyx damage and vascular tone dysfunction impair microcirculatory blood flow, lea

137 Tone-elicited freezing was lower after PRF conditioning

138 esented male and female human listeners with tones embedded within a Western tonal context while reco

139 Spontaneous vasomotor tone, endothelium-dependent dilatation and adrenergic va

140 the implications include decreased arterial tone even if the cardiac index increases.

141 physiological and behavioral responses than tones even prior to conditioning.

142 uctions both deteriorated for high-frequency tones even though they were fully audible.

143 Our results demonstrate that the tone evoked responses and frequency representation in A1

144 the timing of behavioral responses, whereas tone-evoked cortical coupling of Reg-BFCNs predicted cor

145 Surprisingly, changes in short-latency tone-evoked excitatory input cannot explain the effects

146 We recorded tone-evoked MNTB single-neuron activity in vivo using ex

147 We observed that tone-evoked responses are dependent on ACh modulation by

148 show that arousal strongly modulates a slow tone-evoked suppression of recurrent excitation underlyi

149 potential dynamics, spontaneous firing, and tone-evoked synaptic potentials.

150 phase-locked ANF responses to low-frequency tones exhibit spike-rate and temporal asymmetries, but o

151 een postnatal days P12 and P15, during which tone exposure alters the tonotopic topography of A1.

152 previously unknown effects of developmental tone exposure on trajectories of gene expression in inte

153 e mouse brain are modulated by noradrenergic tone fluctuations between arousal states and emphasize t

154 d that BA projectors become activated by the tone-footshock pairing of fear learning protocols.

155 Neither context nor tone freezing behavior was altered by this manipulation

156 onary level increases with the difference in tone frequencies, DF, and the BUF rises faster.

157 rgic input enhances neural discrimination of tones from noise stimuli, which may contribute to proces

158 ented with two interleaved sequences of pure tones from opposite sides and had to indicate the side f

159 ifiers were then trained to decode different tones from their underlying neural activation patterns a

160 as tested since each is essential for SW and tone generation.

161 For tones >=2 kHz, cochlear amplification typically extended

162 Harmonic complex tones (HCTs) commonly occurring in speech and music evok

163 terpinene, did not statistically alter basal tone; however, they induced myorelaxant effects on top o

164 mount, the pitch of the resulting inharmonic tone (IHCT) can also shift, although the envelope repeti

165 n and thereby dynamically shape dopaminergic tone important for normal brain function.

166 However, changes in endogenous opioid tone in AD are poorly characterised and are important to

167 adioligand, to investigate endogenous opioid tone in AD for the first time.

168 n of excitability, [Ca(2+)](i), and myogenic tone in arterial myocytes.

169 asal physiological conditions, noradrenergic tone in awake mice suppresses microglial process surveil

170 s known regarding how regulation of vascular tone in chemoreceptor regions contributes to respiratory

171 ass, and exaggerated hepatic endocannabinoid tone in F1 offspring exposed to 0.1 mg/kg DE-71 relative

172 It can be used to measure sympathetic tone in healthy subjects and in subjects with non-cardio

173 ition of prostaglandin D(2) rescued myogenic tone in high-fat diet-fed control mice.

174 -induced hypertension by preserving myogenic tone in resistance arteries.

175 ponse patterns to taste, enhancing GABAergic tone in rNTS reconfigures the neural activity reflecting

176 ell-free hemoglobin (CFH) increases vascular tone in severe malaria.

177 e CeA may be responsible for hyper-GABAergic tone in the CeA that is observed in individuals who deve

178 ble candidates for the generation of SWs and tone in the IAS.

179 on the critical role of impaired inhibitory tone in the NAc following stress and provide new neuropa

180 suggest a common state of reduced inhibitory tone in the NAc in depression and stress susceptibility.

181 levels were assessed as proxies of autonomic tone in the periphery.

182 mediate the neuromodulation of cardiac vagal tone in the rat model of HFpEF.

183 Furthermore, we report that ex vivo dopamine tone in the ventral striatum and orbitofrontal cortex co

184 re observed in control animals but apoptotic tone in these regions was reduced in ERKdko animals.

185 in L-type Ca2+ channel activity and myogenic tone in two animal models of diabetes.

186 pholemman phosphorylation regulates vascular tone in vitro and that this mechanism plays an important

187 ect meaningful repetition (e.g., consecutive tones in Morse code).

188 pulated by instructing subjects to attend to tones in one ear only, while keeping the rhythmic struct

189 ctations can drive the response amplitude to tones in the human auditory pathway.

190 s counted (and later reported) the number of tones in the pre-specified, target pitch.

191 us-onset-asynchrony (SOA deviants) for given tones in the rhythm.

192 calcium channels that can regulate vascular tone, in modulating AAA formation.

193 e perceptual impact of AN loss on behavioral tone-in-noise (TIN) sensitivity in the budgerigar (Melop

194 rmosets of both sexes while they performed a tone-in-noise detection task and during passive presenta

195 ; 3) tonal + time pressure: the intermittent tone increased in frequency and participants had to walk

196 Cells where enhanced GABAergic tone increased lick coherence conveyed more information

197 suggesting that this dysregulation in opioid tone is common to both behavioural and substance addicti

198 Sympathetic tone is determined by NE release but also by the rate of

199 The study found that overall ANS tone is not altered by mode of delivery in low-risk term

200 new 2-component paradigm wherein thrombotic tone is regulated by both COX1 and COX2 through compleme

201 myogenic vasoconstriction and that myogenic tone is required to maintain local and systemic vascular

202 al processes increase melanocortin signaling tone, leading to anorexia, metabolic changes, and eventu

203 ntext A; infusions were paired with discrete tone-light cues.

204 e propose a mechanism that controls vascular tone, likely along with local neural responses in a mann

205 For some tones <2 kHz, SFOAE amplification extended two octaves a

206 inOutcomeMeasures: Prosthesis symmetry, skin tone match, comfort of wear, and appearance.

207 and suggest that genetic variation in opioid tone may contribute to individual differences in vulnera

208 llosteric site to potentiate endogenous 5-HT tone may provide novel therapeutics to alleviate the imp

209 Our findings suggest that modulatory tone may select a subset of rapid activity-dependent mec

210 Pharmacologically increasing endocannabinoid tone mimics GEE effects on cognition and synaptic transm

211 G responses to attended speech and to simple tones modulated at speech rates (4 Hz) in listeners with

212 particular, we fabricate greyscale and dual-tone nanopatterns with full-width at half-maximum resolu

213 ly to a chord but neither to any constituent tone nor to the other chord.

214 eological features, mainly the darker purple tone observed when blackthorn extract was used in the ic

215 as contrast and homogeneity of the video and tone of the audio in the movie clips are most correlated

216 ischemia, physiologic function and vascular tone of the grafts were evaluated during ex vivo lung pe

217 ly and pharmacologically regulated by the FA tone of the milieu in which each operates-COX-1 in the e

218 s, which, in aggregate, set the inflammatory tone of the tumor microenvironment and determine the pro

219 Using responses to tones of ANFs from cats of both sexes, we show that, for

220 asting by frequencies in harmony with flight tones of known prey.

221 ndent manipulation of attention, as specific tones of the rhythm were presented to separate ears.

222 Ambient striatal GABA tone on striatal projection neurons can be determined by

223 osed rats to identify 7 kHz among distractor tones on an adaptive tone discrimination task.

224 tiate the synaptic excitatory and inhibitory tone onto mutant SF1 neurons, respectively.

225 wo non-compact sound categories (composed of tones or amplitude-modulated noise).

226 s discriminated pairs of amplitude-modulated tones or size-modulated visual objects in the form of a

227 Under simulated low dopaminergic tone our model FSI network produces low gamma band oscil

228 d intervals on a logarithmic scale, even for tones outside the singing range.

229 -0.37 to -0.19; p = 0.03), except for color tone (p = 0.31).

230 Conditioned freezing in response to a tone paired with a weak footshock was immune to the IED,

231 t require participants to extract a coherent tone pattern from a stochastic background of tones.

232 en not behaviourally relevant, we used rapid tone-pip sequences that contained salient pattern-change

233 of regularly repeating patterns within rapid tone-pip sequences.

234 Rats exposed to noise followed by 15 kHz tone pips were not impaired at the same task.

235 band white noise followed by 1 week of 7 kHz tone pips, a paradigm that results in the functional ove

236 nd were distinguishable only by the order of tone-pips.

237 Dichotic tone-presentation allowed for independent manipulation o

238 ito males and females harmonize their flight tones prior to mating in a behavior known as harmonic co

239 ndrogen-induced increases in endocannabinoid tone promote microglia phagocytosis during a critical pe

240 landin D(2) synthesis inhibited the myogenic tone protection in resistance arteries of endothelial Ft

241 We first show that in response to repeated tones pyramidal (Pyr) neurons in male mouse auditory cor

242 We also tone-reared mice (7 kHz pips) during the 3-d critical pe

243 By comparing normal- and tone-reared mice, we found hundreds of genes across cell

244 Pure tones recruited neurons of widely ranging frequency pref

245 ted loci were also involved in smooth muscle tone regulation.

246 ses were selectively enhanced for the target tone relative to the distractor noise.

247 sensorimotor (barostat; sensory thresholds, tone response, compliance), autonomic nervous system (ba

248 We previously showed that inhibitory tone responses of PL neurons correlate with avoidability

249 n (61.1%) underwent neuromotor examinations (tone, responses, senses, and other observations) during

250 s presented during the maintenance of a pure tone resulted in a WM-dependent neural response, providi

251 raveling waves is thought to occur between a tone's characteristic frequency (CF) place and within on

252 perimentally induced AN lesion on behavioral tone sensitivity in noise.

253 mpacting otoacoustic emissions or behavioral tone sensitivity in quiet.

254 inct Names condition), or the same sine-wave tone sequence (Consistent Tone condition).

255 , both for the attended speech, but also for tone sequences modulated at slow rates (4 Hz) during pas

256 reinforced fear (PRF), whereby mice received tone-shock pairings on half of conditioning trials.

257 onditioning, despite an equivalent number of tone-shock pairings.

258 form-mediated active avoidance, rats avoid a tone-signaled footshock by stepping onto a nearby platfo

259 in cortex at the timescale of an individual tone.SIGNIFICANCE STATEMENT Little is understood about h

260 litation in response to HCT relative to pure tones, similar to cortical "harmonic template neurons" (

261 Here, we designed auditory tone stimulation that drove gamma frequency neural activ

262 ion were measured with loudness-matched pure-tone stimuli (0.25-8 kHz).

263 gs of the auditory nerve in response to pure-tone stimuli played from a loudspeaker, support the beha

264 ng both moving band-pass and stationary pure-tone stimuli.

265 ressive way, a phenomenon referred to as two-tone suppression (2TS).

266 ers, larger [Ca(2+)](i), and larger myogenic tone than male myocytes.

267 vel tones centered around the frequency of a tone that matched the tinnitus pitch, f(T), with fixed r

268 esent reflex or persistent increase in vagal tone that may cause refractory symptoms even in a normal

269 e context of SWS-associated neuro-modulatory tone that may reduce feedforward inhibition.

270 matical model that enables calculation of CR tones that accounts for f(T)- and hearing loss-related E

271 attention task during which they attended to tones (that is, externally directed attention) or ignore

272 oscillations, while under high dopaminergic tone the FSI network produces high gamma band activity n

273 fear conditioning, a sensory cue, such as a tone (the conditioned stimulus), comes to predict an inn

274 both conditions, but under high dopaminergic tone, this beta oscillation is interrupted by delta/thet

275 Importantly, despite elevated pure tone thresholds, the frequency tuning of auditory nerve

276 ight gate GABA release and that loss of this tone through elevated AEA hydrolysis increases inhibitio

277 project to the VTA and provide an inhibitory tone to DA(VTA) neurons via both direct and indirect neu

278 hance parasympathetic and reduce sympathetic tone to the heart via central mechanisms.

279 In mice of either sex, we used tones to suppress amplification from different cochlear

280 s could be modulated by variations in a pure tone trajectory as small as 1/24th of an octave, compara

281 Young healthy adults can hear tones up to at least 20 kHz.

282 onal populations was slightly decreased when tone-vocoded vocalizations were tested.

283 s"; that is, their representation of a given tone was contracted towards the preceding trial stimulus

284 Myogenic tone was increased in obese human arteries with FTO inhi

285 pressure; 2) tonal-pressure: an intermittent tone was played at a constant frequency; 3) tonal + time

286 ever a scene appeared, a high or low pitched tone was played, and participants counted (and later rep

287 Rapid frequency modulation of flight tones was observed in all interactions up to acceptance

288 ened to sequences of repeated triplets where tones were separated in frequency by several semitones.

289 ted potentials revealed an attenuated N1 for tones when rhythm predictability was high, while the N1

290 as a selection pressure to reduce GABAergic tone, which in turn reduces energetic needs in a hypoxic

291 al COX1 provides an essential antithrombotic tone, which is masked when COX1 activity is lost in both

292 utton every time they heard a central target tone, while ignoring the peripheral noise bursts.

293 g' animals previously trained to associate a tone with a strong footshock by replacing it with a much

294 aring the time-varying dissimilarity between tones with the predictions of acoustic and perceptual mo

295 patterns coded the perceptual status of each tone within the "tonal hierarchy" of Western music.

296 Our data suggest that a permissive AEA tone within the BLA might gate GABA release and that los

297 0 ms reflected the perceptual status of each tone within the tonal hierarchy of Western music.

298 f glucose in fasted mice activated the vagal tone without affecting blood pressure.

299 rontal operculum and a lower parasympathetic tone, without significant effect of the clinical group o

300 nactivation of inhibitory neurons during one tone would decrease the response of A1 neurons to a subs