ライフサイエンスコーパス: too much

1 tudies find too little activation and others too much.

2 rouble falling or staying asleep or sleeping too much.

3 l harm caused by administering too little or too much.

4 ot when doctors' diagnostic accuracy differs too much.

5 the balance between treating too little and too much.

6 Too much acid can induce esophageal, gastric, and duoden

7 Too much acid can induce gastroduodenal injury.

8 Too much acid can lead to gastroesophageal reflux diseas

9 They can also contain too little or too much active ingredient or no active ingredient at al

10 r T3SS function and acute virulence, whereas too much activity can trigger an apparent stress respons

11 Thus, too much adaptation would result in disregarding informa

12 does not provide sufficient traction whereas too much adhesion renders cells immobile.

13 s clearance substantiates the principle that too much affinity improvement, i.e., beyond that of N434

14 static and cytotoxic activity by series 1-9, too much alkylation results in loss of cancer selectivit

15 iffusion is found to play an important role: too much and initial perturbations are smoothed away, to

16 ple Return mission to around $11 billion was too much and the 2040 return date was too distant.

17 lopment: too little and valves fail to form; too much and the valves thicken and cannot close properl

18 We identified samples with both too much and too little active drug content.

19 However, PFC decoding shows both too much and too little.

20 f the potential insidious dangers of sitting too much and who are not taking advantage of the benefit

21 e modestly in excess of 1.0 ("enough but not too much") and should tend to be similar for the various

22 g autoimmune and neurodegenerative diseases (too much apoptosis) or the growth of tumors (too little

23 However, entrusting too much autonomy endangers patient outcome, while entru

24 be tightly controlled because too little or too much autophagy can be deleterious to cellular physio

25 Too much because cognitive theories of consciousness do

26 y synthesized ER client proteins, yet having too much BiP inhibits folding.

27 , and care will be necessary to avoid taking too much blood from these donors.

28 classically shown that either too little or too much bodily arousal is detrimental to decision-makin

29 rast, when asked how often patients receive "too much" care, 46% of respondents said "sometimes or fr

30 isorder and among those who reported working too much, career dissatisfaction, less control at work,

31 n: too little inhibits fork restart, whereas too much causes fork degradation.

32 and signaling roles in mammalian cells, but too much cholesterol can cause cytotoxicity.

33 cells characteristically fire too little or too much compared with expectations from the random mode

34 Current weather models require too much compute and lack the necessary predictive capab

35 to CCN than previously reported, which means too much cooling if incorporated into present climate mo

36 nce a high proportion of these patients have too much coronary calcium to allow accurate assessment o

37 rtain zones like eyelids, and about applying too much corticosteroid.

38 o meet sampling assumptions, or by incurring too much cost and logistical burden for most projects to

39 ling networks to integrate multiple stimuli, too much cross-talk may compromise the ability of the ne

40 highly twisted and gives the entire compound too much curvature to fit well to the shape of the minor

41 dose-response, whereby either too little or too much D1R stimulation impairs spatial working memory.

42 Too much dehydration resulted in tough textures and unac

43 acteria can directly contact the epithelium, too much depletes the protective microbiota, creating a

44 activity in the DH, with both too little and too much DH activity impairing NOR memory.

45 Etymologically, overdiagnosis means too much diagnosis and stems from the inability to disti

46 c regimen is being advocated in a manner not too much different from that advocated for the treatment

47 stain clusters that are otherwise transient, too much dilutes the pattern.

48 If the seeding conformations lead to too much divergence in the energy landscape, it could im

49 entrations (e[CO(2) ]), there is a risk that too much early growth might deplete soil water and lead

50 Can we ever have too much ecological field data?

51 ublished work, 80% reported that it required too much effort to produce the materials or information;

52 ibe discomfort, whereas only 16.7% selected "Too much effort" on its own (P < 0.001).

53 ough air" on its own or in combination with "Too much effort" to describe discomfort, whereas only 16

54 erogeneity in remission and recovery, places too much emphasis on a compulsive dimension of addiction

55 ts with residual disease, this method places too much emphasis on residual depth of invasion and fail

56 Many reports put too much emphasis on subgroup analyses that commonly lac

57 g is required for neurovascular development, too much endothelial WNT signaling, as well as overexpre

58 gies over-predicted species presence, due to too much environmental distance between the pseudoabsenc

59 Hence, too much FadR is bad.

60 mice with too little fat (lipodystrophy) or too much fat (ob/ob), leptin deficiency leads to hypergl

61 other organs to prevent the accumulation of too much fat and to protect adults against obesity.

62 By definition, obesity is too much fat, and we here review efforts to treat obesit

63 tely, at present, chocolate products contain too much fat, leading to obesity.

64 al to the neural circuit concerned; however, too much feedback causes runaway firing (instability), a

65 uggested a strong negative selection against too much Fer protein and pointed to a critical cellular

66 the field of conservation biology has placed too much focus on conserving genome-wide genetic variati

67 We reason that these results come from too much focus on reproducing the electrochemical behavi

68 s enterprise, we are concerned that there is too much focus on the behavior of the teacher, without e

69 d a lack of hands-on training as a result of too much focus on theory.

70 in biomedical imaging may increase the size too much for renal clearance.

71 Too little or too much force can trigger cell death, yet factors that

72 Too much FOXA1 creates excessive open chromatin regions,

73 local target compound concentration differed too much from the concentration of the single label.

74 degrees metal-ligand-metal geometry deviates too much from the established strategy of using ligands

75 ations in randomized clinical trials deviate too much from the general population, it undermines the

76 Too much fructose in the diet can worsen metabolic probl

77 This would result in too much geoengineering: the country with the highest pr

78 We hypothesize that too much gliadin incorporation in the glutenin network d

79 is without shock, but IDSA believes there is too much heterogeneity and difficulty defining this popu

80 and increased donation; we hypothesized that too much heterogeneity exists in transplantation systems

81 s from the standard neutral model, including too much heterogeneity in synonymous site polymorphism r

82 However, too much IKs under basal conditions poses an arrhythmoge

83 Too much IL-10 at one end of the scale may suppress othe

84 een radiopharmaceuticals should not be given too much importance when one is choosing radiopharmaceut

85 rouble falling or staying asleep or sleeping too much in an electronic patient-reported outcome measu

86 Overall, the data available vary too much in terms of treatment protocols, patient mix an

87 e difficult to resolve from M1 activity; and too much, in that motor commands are tangled up with non

88 ical component in defense against pathogens, too much inflammation is harmful.

89 that the zebrafish maternal-effect mutation too much information (tmi) corresponds to zebrafish prc1

90 that activity in M1 has both too little and too much information for optimal decoding: too little, i

91 learning what to ignore when confronted with too much information, so that experience can properly ge

92 ges occurred because of 5 types of problems: too much information, too little information, inaccurate

93 to balance between gathering too little and too much information.

94 There is too much inherent variability in the DAS and other RA sc

95 Too much interconnectivity, however, becomes detrimental

96 We show that too much interface flexibility disrupts network formatio

97 patients have too little ability to focus or too much interference from distraction has not been clar

98 Too much interpersonal synchrony is considered detriment

99 Too much iodine increases the incidence of Hashimoto's t

100 Too little or too much iron can have important clinical consequences.

101 ow levels of iron cause human disease, while too much iron is toxic.

102 creased red meat consumption, the effects of too much iron supplementation during pregnancy have beco

103 Because defective cell death (too little or too much) is implicated in various diseases (like cancer

104 array ideas is developed, which should scale too much larger datasets than those currently handled by

105 light for photosynthesis, but absorption of too much light can lead to photo-oxidative damage to the

106 mit the measurements in systems that scatter too much light.

107 nd, above all, personal flexibility-with not too much long-term planning.

108 interferometric stability requirements, and too much loss.

109 and ensure that the cell has enough, but not too much, LPS.

110 rent implementations use a single core, take too much memory to represent the result, and do not prov

111 ly large amount of iron and the oxidation of too much methane if global anoxia was to be maintained.

112 Therefore, too little or too much negative selection to a self-antigen can result

113 Too much NMDA receptor activity is harmful to neurons -

114 We find that the NMF contains too much noise to be directly useful without measurement

115 derstand much more about the risks of having too much of a critical nutrient.

116 ependent pathway requires 5-7 days, which is too much of a delay to block quickly replicating pathoge

117 However, too much of a good thing can be bad.

118 "Too much of a good thing" perfectly describes the dilemm

119 However, 'too much of a good thing' can be deadly, and the excess

120 or clinical research, however, it has become too much of a one-size-fits-all mechanism.

121 oma profiles (e.g., dessert wines), is often too much of an analytical challenge.

122 ns but can also be toxic if cells accumulate too much of this essential metal.

123 global chemistry models calculate about 15% too much OH and thus too rapid methane loss.

124 We argue that the target authors focus too much on adaptive behavioral responses and not enough

125 In the meantime, some previous methods focus too much on removing difference between batches, which m

126 rmation and data, and will suffer if we rely too much on technology to remember things for us.

127 Putting too much onus on a single mutation could enhance a crisi

128 ADPT were explained by controllers providing too much or little assistance versus actual task demands

129 in schizophrenia are not reducible to simply too much or too little activity but, rather, reflect a c

130 rmal development and tissue homeostasis, but too much or too little apoptosis can also cause disease.

131 Because too much or too little autophagy can be detrimental, the

132 Is it a case of too much or too little Ca(2+) influx causing cell death

133 Too much or too little CrGAP activity leads to defects i

134 The former interaction implies that too much or too little dopamine signaling and reward reg

135 Results imply that too much or too little dopamine signaling and reward reg

136 nicated effectively, decision makers may put too much or too little faith in it.

137 Clearly, packing too much or too little fuel would lead to suboptimal con

138 esis lie between two undesirable extremes of too much or too little internal secondary structure.

139 However, too much or too little light or rapidly fluctuating ligh

140 ling experiments, to check for problems with too much or too little novelty in the validation data.

141 difications are essential for human health - too much or too little of them leads to serious illnesse

142 , transcriptome instabilities in the form of too much or too little RNA editing activity, or misguide

143 losion of diverse drugs to treat problems of too much or too little sleep, the detailed mechanisms of

144 It has been established that too much or too little STAT activity disrupts follicle c

145 strength (and less so for sgRNAs that induce too much or too little target depletion).

146 Too much or too little tau in glial cells enables the ac

147 ncongruent with neutral evolution: They have too much or too little variation.

148 that if access to hospital care was reduced too much, or if decreased hospital use was not offset by

149 This review summarizes how too much, or too little, calcium release can lead to arr

150 ther statistically indistinguishable or show too much overlap to be labeled characteristic.

151 r understanding pathologies of too little or too much oxygen.

152 wild-type mitochondrial DNA, suggesting that too much Pet127p prevents mitochondrial gene expression.

153 ndings support the notion that too little or too much PI3K activity leads to immunodeficiency.

154 s typical of von Willebrand disease, whereas too much platelet adhesion may cause thrombotic thromboc

155 l genetic defects and acquired disorders has too much potential to abandon.

156 , modulators, filters and detectors) consume too much power for the high-speed femtojoule-class links

157 ntennas the strong electric field dissipates too much power into body tissues.

158 lasers plus external modulators consume far too much power to be competitive with future electrical

159 Computationally, we consider too much precision afforded to negative prior beliefs as

160 nding how loss exposure-both "too soon" and "too much"-predicts poor health and earlier mortality.

161 However, not too much progress has been made in this field.

162 in switching result in either too little or too much proliferation.

163 is highly regulated, as both too little and too much RAD51 activity can cause genome instability.

164 on and crystallinity of the acceptor polymer too much reduces the photovoltaic performance as the don

165 However, certain types of selfhood and too much selfhood can both be detrimental to group funct

166 Too much shielding causes the cyclonic and anticyclonic

167 ecular, physiologic, and clinical effects of too much sitting (inactivity physiology) separate from t

168 should not only reduce the specific risks of too much sitting but also have a positive effect on the

169 Sedentary behaviour - put simply, too much sitting, as a distinct concept from too little

170 ng the adverse public health consequences of too much sitting.

171 tics, the vast majority of US adults consume too much sodium and too little potassium.

172 s, particularly non-Hispanic blacks, consume too much sodium, and nearly all do not consume enough po

173 ilization was that such instruments "require too much staff time."

174 results when mechanical ventilation imposes too much stress on the pulmonary parenchyma.

175 s for sequence differences is also critical: too much stringency will prevent recombination between d

176 With some but not too much sulfur, CoP exhibited a higher hydrogenation pr

177 racters, and without developed attributes or too much sweetness.

178 s recolonization of extinct patches, whereas too much synchronizes subpopulations, raising the likeli

179 Whether the U.S. health care system supports too much technological change-so that new technologies o

180 ion is often interpreted by patients to mean too much tension.

181 If it decreases too much, the pulse will eventually collapse while if it

182 ically unfit in the coming years if they sit too much, thereby limiting the normally high volume of i

183 braced in primary care: e-health often takes too much time and is too expensive; the quality of Web-b

184 sing overlap graphs suffer from the need for too much time and space in constructing the graphs.

185 to kinetically deficient proteins that spend too much time at nonspecific sites before reaching their

186 Why do we sometimes spend too much time on seemingly impossible-to-solve tasks ins

187 ciated and one hypothesis is that they spend too much time out of torpor during hibernation, depletin

188 r radioimmunotherapy for NHL thought it took too much time to administer radioimmunotherapy (P < 0.01

189 ed were "embarrassment", "worry", and "takes too much time".

190 ticipating are the perceptions that it takes too much time, is too expensive, and is not required for

191 lve many imaging sequences and often require too much time.

192 ctioning, and staining of the tissue require too much time.

193 al in primary care settings because it takes too much time.

194 ve been associated with either too little or too much TLR4 activation.

195 But, when too much TNF-alpha is produced as in autoimmune diseases

196 ts in increased bacterial clearance, whereas too much TNFalpha results in many of the hallmarks of ba

197 ecies considered in this study have diverged too much to allow the construction of all-encompassing e

198 felt pain) and pain tolerance (when pain was too much to bear) were assessed with an algometer.

199 Self-reported rate of "having had too much to drink" declined 49% from 0.43 to 0.22 times

200 ometimes, the amount of roots in a sample is too much to fit into a single scanned image, so the samp

201 of such improvements, it does not seem to be too much to imagine that determining the structural basi

202 lity that in medicine today there is simply "too much to know." This is particularly true for those c

203 ween different alleles of the same gene, but too much tolerance will lead to illegitimate recombinati

204 tions exist: too little, too late (TLTL) and too much, too soon (TMTS).

205 2015 BZ509 was discovered in 2015, but with too much uncertainty in its measured orbit to establish

206 oach fails in polyhalogenated systems, where too much valuable information is lost.

207 I conclude that placing too much value on novelty could have counterproductive e

208 sensor) generate too little facilitation and too much variance.

209 ycaemia is recommended at all times, but not too much vitamin C.

210 precludes dissolution of the reactants while too much water favors hydrolysis over condensation.

211 However, these two measures assign too much weight either to rare lineages or to most abund

212 ecision tasks, observers consistently placed too much weight on perceptual uncertainty relative to ac

213 er, in classical tasks, people appear to put too much weight on unlikely events.

214 mood', 'Uncontrollable worry', and 'Worrying too much' were the most central symptoms, while 'Sad moo

215 endency of radiologists to agree with AI CAD too much (when AI CAD made an erroneous flagging) or too

216 cient IRF1 to prevent tumorigenesis, yet not too much which could drive excessive immune activation.

217 f extreme burden and burnout associated with too much worry unsolved.