ライフサイエンスコーパス: too

1 applications can be a "real" cell biologist, too.

2 e UK 9, Italy 3, Spain 2 and other countries too.

3 entration had major effects on drug release, too.

4 d growth rates, its proteostasis system must too.

5 lls may shape aspects of olfactory cognition too.

6 ) protein inhibited myoblast differentiation too.

7 t enrollment is often based on other factors too.

8 SA and its frequency is increasing in Europe too.

9 hat we show rings true for invertebrate ears too.

10 pes, which was preserved after cold storage, too.

11 r improved viral detection techniques is all too apparent.

12 approaches to mental illness has become all too apparent.

13 are diagnostic of CBD(7,8); by SDS-PAGE, so too are detergent-insoluble, 37 kDa fragments of tau(9).

14 ructured and task dependent, suggesting they too are under volitional control.

15 However, fundus cameras are too big and heavy to be transported easily and too costl

16 eters (energy per cycle and power) are still too bluntly defined to pinpoint the precise biophysical

17 Receptor activity that is either too brief or too protracted fails to sufficiently open T

18 ion has recently been criticized as possibly too broad and unspecific.

19 ammox Nitrospira were abundant and increased too, but their relative abundance within the AOP decreas

20 Mice, too, can perceive stereoscopic depth, and neurons in pri

21 endpoint for diabetes control may have been too challenging to achieve.

22 Vancomycin infusion, initiated too close to surgical incision, predicted increased SSI

23 sets derived from weather stations are often too coarse to capture the conditions experienced by orga

24 are reported at the state-level-a resolution too coarse to detect community-level clustering of nonva

25 esolution of existing land cover datasets is too coarse, large-scale land cover changes in the Arctic

26 ns caused by resistant bacteria are nowadays too common, and some pathogens have even become resistan

27 tes, resistance to these therapies is an all-too-common occurrence.

28 However, the original miRAMM workflow is too complex for the throughput needed to analyze a large

29 ation of labile SOM, however these are still too complex to examine beyond compound classes.

30 sumption can, however, either render a model too complicated for making conclusions or it can prevent

31 However, if individuals are too conformist or too greedy, markers fail to shape soci

32 This would be too conservative because it assumes all tests are indepe

33 rrying primary LOH tracts revealed that they too contained unselected structural alterations more oft

34 o big and heavy to be transported easily and too costly to be purchased by every health clinic, so fu

35 olding for a pair of RNAs is O(N6), which is too costly to be used for large-scale analysis.

36 nfluenced by metabolite concentrations, they too could show linear anatomical variation.

37 colorectal and pancreatic cancers are either too cytotoxic or insufficiently efficacious for GC.

38 xed paraffin-embedded (FFPE) tissue is often too degraded for quality sequencing.

39 But Bratman's makes the explanation too difficult to succeed, and Gilbert's makes it too eas

40 each functional half of everninomicin P are too distant for bidentate binding, ligand displacement s

41 ractions depend on population abundances, so too do the effects of environment, as when drought is am

42 hat as years of formal schooling increase so too does health and wellbeing; however, it is unclear wh

43 of single-molecule experiments improves, so too does the breadth, quantity and quality of informatio

44 idence time increase at a given location, so too does the chance of a commercial poultry AI outbreak.

45 sks posed by IAS need to be assessed, but so too does the feasibility of their management.

46 , or where endosperm cellularization happens too early, too late, or not at all.

47 difficult to succeed, and Gilbert's makes it too easy.

48 based CO(2) capture processes are considered too energetically expensive for widespread deployment.

49 fect correction, beyond which long reads are too error-prone to be corrected by these methods.

50 natural environments, but in built-up areas too, even after controlling for the presence of green sp

51 that bacterial flagella are too straight and too far apart to form tangled bundles based on their int

52 ever, existing crystal structures place them too far apart to interact directly.

53 and glutamine bound in the active site, but too far away from SAM to be methylated.

54 The location of the K1-cluster, too far away from the SAM binding site, supports a mecha

55 ingle energy function may take the structure too far away without a constraint.

56 asymmetry disappears when the growth rate is too fast or too slow and is most significant for typical

57 Although SARS-CoV-2 is spreading too fast to be contained by manual contact tracing, it c

58 be slips rather than steps because they are too fast to consist of multiple, tightly coupled 8-nm st

59 However, TF binding studies in plants are too few in number to produce a general picture of this c

60 y and high plasma folate, because there were too few individuals (<1% of the cohort) in this category

61 the randomized-withdrawal period, there were too few recurrence events in the rilonacept group to all

62 nuclei, suggesting that single-units may be too-fine grained to shed light on the mesoscale organiza

63 Choosing a class is either too flexible or too restrictive results in poor genotypi

64 loops, whereas NMR structures are typically too floppy overall.

65 of cumulative technological culture has been too focused on social cognition and has consequently neg

66 Only when the environment changes too frequently, a unicellular state evolves which relies

67 may present details of the analysis that are too granular for a clinical readership to assess.

68 between years, while the second implies far too great an increase in respiration during stand develo

69 ly because evolution occurred over distances too great to influence most ecological patterns.

70 owever, if individuals are too conformist or too greedy, markers fail to shape social interactions.

71 required for effective energy harvesting are too hard and brittle for seamless integration into weara

72 n sequencing technologies have developed, so too has RNA-seq.

73 bit substantial phalangeal curvature, which, too, has been interpreted as a direct result of habitual

74 can go unnoticed when assessment is focused too heavily on simulated data, where the alignment task

75 summarized narratively because studies were too heterogeneous to conduct meta-analysis.

76 nce intervals based on the RR estimator were too high and became worse as more observations were impu

77 ed to occupy a 3c-4e sigma* orbital which is too high in energy to be reachable.

78 Selecting too high number of gates results in a loss of signal-to-

79 symptomatic mitral regurgitation who are at too high of a risk to undergo open heart surgery.

80 traints, such as avoiding excess repeats, or too high or too low windowed guanine-cytosine (GC) conte

81 suggested that both these values are either too high or too low.

82 equent problems are running experiments with too high precursor concentrations, too high UV and/or to

83 groups where the inferential uncertainty is too high to support a transcript-level result.

84 ents with too high precursor concentrations, too high UV and/or too low humidity.

85 ree that global greenhouse gas emissions are too high, but prefer other countries reduce emissions ra

86 emperature of ~300 K at 2.7 Ga, which may be too high, given evidence for glaciation at roughly this

87 lution or, when configurational lability was too high, through VT-HPLC analysis on the chiral station

88 benefits if the concentration of extract is too high.

89 r metals would be regarded as "standard" are too high.

90 r are resident in, an oil reservoir normally too hot for germination and growth, explaining observati

91 ed nucleic acids are enzymatically unstable, too hydrophilic for cell uptake and payload encapsulatio

92 ic representativeness, exclusion of patients too ill to participate, missing viral load data, greater

93 od (<2 weeks), and in those with WON who are too ill to undergo endoscopic or surgical intervention.

94 Specific gene mutations were too infrequent in patients with specific 11q23/KMT2A rea

95 vements, but we found that beta-bursts occur too infrequently to account for observed stopping behavi

96 of saccades, we found that beta-bursts occur too infrequently to account for the observed stopping be

97 These structural variations, however, appear too insignificant to explain the slowness of the beta-oc

98 ss, using extrinsic contrast agents is often too invasive for routine clinical operation.

99 int by recoding mRNAs; however, this process too is thought to be restricted to the nucleus.

100 sliding velocity and hence erosion, but this too lacks empirical scrutiny.

101 lists of overrepresented GO terms are often too large and contains redundant overlapping GO terms hi

102 n exact support recovery if the noise is not too large and develop a fast Noise Collector algorithm,

103 This response can be elicited by pLL too large for phagocytosis and nonetheless requires acti

104 ials allows for reactions of bulky molecules too large to access interior pores.

105 oo small to make any general inferences, nor too large to be biologically interpretable.

106 the growth of prion particles until they are too large to be transmitted.

107 es have proposed that intact viral cores are too large to fit through nuclear pores and uncoating occ

108 weak tides because the surrounding ocean is too large to host tidal resonances.

109 The round form of CLas is too large to move, but can change its morphology to enab

110 mates of hundreds of thousands of people are too large(5,6).

111 lly formed a protein-starch complex that was too large, instability and collapse of the structure can

112 tonnes of carbon is approximately five times too large.

113 Second, alpha-band modulation occurred too late to account for spatially directed behavioral re

114 being rapidly developed but will likely come too late to affect the first wave of a potential pandemi

115 to reconcile with the finding of modulation too late to contribute to movement cancellation in media

116 o not eventuate, sensory information arrives too late to prevent the visual system from representing

117 endosperm cellularization happens too early, too late, or not at all.

118 endangers patient outcome, while entrusting too little autonomy results in expertise gaps at the end

119 g. by a facilitation fusion sensor) generate too little facilitation and too much variance.

120 Clearly, packing too much or too little fuel would lead to suboptimal conditions for

121 d framework for understanding pathologies of too little or too much oxygen.

122 Too little shielding and small depth lead to merging and

123 uses an accumulation of plasmanyl species, a too little studied but biologically important substance

124 n pair is neither too solvent-stabilized nor too little.

125 For too long this vision has been the fight of a heroic few,

126 to fully characterize a current is typically too long to be applied in a single cell.

127 imply hHsp90alpha occupies the closed state too long to function effectively in yeast, and define an

128 e a dismal situation that has lasted already too long.

129 ed pattern, eDNA concentration was generally too low for accurate quantification.

130 However, the hologram bandwidth has remained too low for any practical use.

131 gen detection even when the pathogen load is too low for direct identification.

132 n, even when free sulfide concentrations are too low for formation of Sb-sulfur precipitates, peat NO

133 SMFC produces a voltage of 1.16 V, which is too low for practical application.

134 eltaS(EC) /DeltaE and DeltaT(EC) /DeltaE are too low for practical applications.

135 ch Bio-SPME chemical biopsy tools are deemed too low for quantification when porous polyacrylonitrile

136 y of the pseudoknotted conformations was far too low for static pseudoknots to account for the high l

137 precursor concentrations, too high UV and/or too low humidity.

138 ts in a loss of signal-to-noise ratio, while too low number of gates does remove only part of the mot

139 ency in citrus via CRISPR technology remains too low to be implemented for genetic improvement in pra

140 n another community in which transmission is too low to be self-sustaining.

141 included studies for the other tracers were too low to combine, but sensitivity and specificity rang

142 the incidence of mortality and morbidity was too low to demonstrate any effect.

143 the actual rate of cardiomyocyte renewal is too low to efficiently counteract substantial cell loss

144 on smaller particles the size of proteins is too low to overcome diffusive action.

145 ld marine sediments where the temperature is too low to support growth and activity of thermophiles i

146 h as avoiding excess repeats, or too high or too low windowed guanine-cytosine (GC) content.

147 If coverage is too low, an additional re-sequencing test is needed to m

148 w that this is impossible if their memory is too low.

149 hat both these values are either too high or too low.

150 ent study indicates that this number is much too low.

151 bacteria can readily evolve phage resistance too, making it crucial for modern phage therapy to devel

152 As such, it accommodates too many alternative historic scenarios, yet remains una

153 KNL1 minimize chromosome missegregation, but too many delay anaphase onset.

154 h may have occurred because the SOI contains too many high-frequency components, making prediction di

155 In far too many instances, studies suggest and speculate mechan

156 Evaluation of too many markers will not only increase the cost but als

157 We simply have too many materials to be processed using conventional, b

158 cluding clinical trials, is out of reach for too many patients.

159 There are too many plausible permutations and scale-up scenarios o

160 Too many pre-clinical experiments are giving results whi

161 ling persistently 'time poor'-like they have too many things to do and not enough time to do them.

162 nce datasets can contain terabytes of reads, too many to be coassembled together on a single shared-m

163 ssic cytotoxic chemotherapy, this treatment, too, may be accompanied by considerable side effects and

164 may be because children are asymptomatic or too mildly infected to draw medical attention and be tes

165 However, when blowflies breed on the carrion too, mites enhance beetle reproductive success by eating

166 However, entrusting too much autonomy endangers patient outcome, while entru

167 o meet sampling assumptions, or by incurring too much cost and logistical burden for most projects to

168 entrations (e[CO(2) ]), there is a risk that too much early growth might deplete soil water and lead

169 Hence, too much FadR is bad.

170 other organs to prevent the accumulation of too much fat and to protect adults against obesity.

171 local target compound concentration differed too much from the concentration of the single label.

172 This would result in too much geoengineering: the country with the highest pr

173 Clearly, packing too much or too little fuel would lead to suboptimal con

174 r understanding pathologies of too little or too much oxygen.

175 Computationally, we consider too much precision afforded to negative prior beliefs as

176 on and crystallinity of the acceptor polymer too much reduces the photovoltaic performance as the don

177 Too much shielding causes the cyclonic and anticyclonic

178 ng the adverse public health consequences of too much sitting.

179 sensor) generate too little facilitation and too much variance.

180 lly arranged around a beta-stranded channel, too narrow to accommodate DNA.

181 However, CRISPR/Cas9 edited F(0) animals too often demonstrate variable phenotypic penetrance due

182 duce errors that, in biological studies, are too often ignored.

183 Trauma patients are too often qualified for WBCT.

184 Most cigarette smokers who wish to quit too often relapse within the first few days of abstinenc

185 Too often, genetic interpretations falter with ahistoric

186 verexposure, such as listening to loud music too often, results in noise-induced hearing loss.

187 dead Li that cause poor performance and, all too often, spectacular failure.

188 (NIMH) 'fast-fail' approach seeks to improve too-often-misleading early-phase drug development method

189 s and Old World monkeys of 65 million years, too old to be consistent with the fossil record; reconci

190 al forest carbon sink persistence are likely too optimistic, increasing the need to curb greenhouse g

191 Exclusion criteria were being too physically unwell to attend clinic (bedridden), psyc

192 to the inner-segment mitochondria, they may, too, play a role in the inner-segment mitochondrial arra

193 ation from many of these sites are currently too poorly resolved to corroborate this.

194 ls of its electron-relaying FeS clusters are too positive relative to the 2H(+)/H(2) couple at neutra

195 eceptor activity that is either too brief or too protracted fails to sufficiently open T-type channel

196 o occur when the applied potential is varied too quickly-causing sluggish dynamics.

197 Observed changes in fish abundance occurred too rapidly to be explained by recruitment or mortality,

198 text of arbitrary length and terms that are too rare for standard meta-analysis.

199 s and detects resistance-associated variants too rare to be likely picked up by correlation-based tec

200 d outcomes, obtaining these metrics has been too resource intensive for large-scale use.

201 ime series as a dynamical system suffer from too restrictive assumptions about the type of kinetics,

202 Choosing a class is either too flexible or too restrictive results in poor genotyping performance.

203 curate, but crystal structures are typically too rigid in loops, whereas NMR structures are typically

204 owever, these same assumed growth models are too rigid to recapitulate patterns observed in many expe

205 e (CO(2)) emissions from these sediments are too scarce to upscale emissions for global estimates or

206 But QT interval is too sensitive a marker and not selective, resulting in m

207 indow, and the local lattice distortions are too severe to recover quickly.

208 At a depth that is too shallow for hydrate formation, existing theories sug

209 These data are too short for assessing possible multidecadal or centenn

210 However, in some cases RO(2) lifetime can be too short for atmospherically-relevant RO(2) chemistry,

211 However, one-week period was too short for the CM to convert miPSCs into CSCs.

212 ths, and that transition steps may have been too short to achieve the full potential impact of the CQ

213 r high copy number SOD1 mutant mice might be too short to acknowledge benefits of transplanted cells.

214 ane activity that the instrumental record is too short to address.

215 e are able to analyze time traces, which are too short to be analyzed by existing methods, including

216 we measure folding on DNA molecules that are too short to form loops.

217 urrently ongoing, even though timeseries are too short to make climatological assessments.

218 e of Whites' experience of COVID-19, then so too should the tools we deploy to fight it.

219 phic generalizability, exclusion of patients too sick to consent, fluctuations in procedures in the s

220 (death or removal from the list due to being too sick to undergo transplant, n = 339) or 180 days.

221 ucation predicted the MELD at delisting for "too sick" (P < 0.05).

222 ts should include waitlist removal rate for "too sick" and waitlist death ratios, so waitlist managem

223 ck." RESULTS: We included 5250 delisted for "too sick" at 127 centers, in 53 DSAs, over 16 years.

224 that the mortality of patients delisted for "too sick" is unexpectedly low.

225 There is variation in delisting MELD for "too sick" score across DSA and time.

226 Delisting for being "too sick" to be transplanted is subjective.

227 ics may be associated with determination of "too sick" to transplant.

228 The mean MELD at delisting for "too sick" was 25.8 (SD +/- 11.2).

229 waitlist events (LT and dropout for death or too sick) were calculated and modeled using Fine and Gra

230 nter outcome rates were 72.6% LT, 18.2% died/too sick, and 6.1% SS.

231 Predicted outcome probabilities (LT, died/too sick, spontaneous survival [SS]) were obtained with

232 heir best clinical judgment for determining "too sick," but it is unclear how social determinants inf

233 Patients were included if delisted for "too sick." Our primary outcome was Model for End-Stage L

234 isease (MELD) score at waitlist removal for "too sick." Regression assessed the association between s

235 social determinants and MELD at removal for "too sick." RESULTS: We included 5250 delisted for "too s

236 erminants influence decisions to delist for "too sick." We hypothesized that social determinants and

237 ity by generating conformations that are not too similar to each other, and is also computationally f

238 efugia model to explain past TRF dynamics is too simplistic.

239 CMZ activity over the course of evolution is too simplistic.

240 sappears when the growth rate is too fast or too slow and is most significant for typical growth cond

241 aration or cleanup prior to analysis and are too slow for large-scale screening campaigns.

242 pplications where current methods are either too slow or are destructive.

243 even higher barriers, which would lead to a too slow reaction, when the electrochemical gradient acr

244 , at high velocities, molecular diffusion is too slow to be effective, and the molecules pass through

245 This NCX-dependent release was too slow to be involved in channel activation, but expla

246 Although too slow to be involved in channel activation, this Na(+

247 Using AN, rates were too slow to be quantified using DLS, but particles forme

248 h a rate constant of only 4.1 x 10(4) s(-1), too slow to compete with other processes such as radical

249 (ChR2) used for cell-specific activation are too slow to follow the high rates required for effective

250 pid recovery as observed in Aldabra's lagoon too slow to prevent long-term reef degradation, even at

251 a chemical reaction that would be otherwise too slow under diluted conditions.

252 tional regulators and their promoters may be too slow.

253 therefore the loss of resistance may proceed too slowly to be of practical importance.

254 , 276-293 (1928)] is not, since it converges too slowly.

255 understand why the signal-to-noise ratio is too small in current climate models(10), and the extent

256 imply due to limited statistical power (with too small sample sizes).

257 servation focuses on spatial scales that are too small to adequately address these impacts.

258 s of the pore openings of both materials are too small to admit either guest, signalling the importan

259 evaluated for nivolumab discontinuation was too small to assess the value of this approach.

260 y relevant precursors and early cancers were too small to be detected.Keywords: Genital/Reproductive,

261 s ramifying repeatedly, but the branches are too small to be followed to their tips with SBSEM at low

262 d, silicon-based, functional robots that are too small to be resolved by the naked eye.

263 DNA) in mammalian tissues and cell lines are too small to carry protein coding genes.

264 y few clinical trials, and most of these are too small to detect moderate treatment effects.

265 Because a neutrophil is too small to engulf the entire aggregate, it must be abl

266 mer on the surface of pure water droplets is too small to host the whole process.

267 he individual modules (clusters) are neither too small to make any general inferences, nor too large

268 With a donor pool too small to meet demand and unacceptably high mortality

269 arine protected areas around coral reefs are too small to protect reef-associated sharks.

270 sunlight to minimize heat absorption but are too small to reflect human-body midinfrared radiation to

271 e droplets and large quantities of particles too small to see by eye.

272 lude that the numbers of training cases were too small, and the features used in the models were not

273 only when the incipient ion pair is neither too solvent-stabilized nor too little.

274 e-cell studies because action potentials are too sparse and the deflection response to drifting grati

275 lds single-nucleotide mutation data that are too sparse for current single-cell analysis methods.

276 Data on ice hockey and martial arts were too sparse to allow conclusions to be drawn.

277 robust, expensive to manufacture, and often too specific for a single desired substrate, lacking des

278 plicating micelles, our vesicular system was too stable to surfactant degradation to be maintained ou

279 results suggest that bacterial flagella are too straight and too far apart to form tangled bundles b

280 n models, the paradoxical effect implies not too strong recurrent excitation.

281 t common methods of combination analysis are too susceptible to noise to support robust scientific co

282 However, existing copper chelators are too toxic or ineffective for cancer treatment.

283 e cells using a drug that would otherwise be too toxic to administer systemically.

284 e Abeta42 conformers that might otherwise be too transient and dynamic to study, and we identify site

285 tion of challenging substrates but are often too unstable to be isolated.

286 on and the solid state, several of which are too weak - or are disfavored compared to other binding m

287 The measure of scam awareness used here is too weak for prediction at the individual level.

288 ifferential IMS (LODIMS), where the field is too weak for significant heating but suffices to lock th

289 nately, hyperfine interactions are typically too weak to address single nuclei.

290 niche divergence or selection in sympatry is too weak to overcome gene flow from allopatry.

291 volutionary reasons, anticancer defenses are too weak, given cancer risk, older females could not pur

292 es(1,2), gravity empties atom traps that are too weak.

293 climate models suffer from too-weak NDH and too-weak linear dynamical ocean-atmosphere coupling.

294 Most climate models suffer from too-weak NDH and too-weak linear dynamical ocean-atmosph

295 ical convergence zone problem'(12,16,17) and too-weak responses to ENSO(15).

296 surgical procedures can shunt aqueous humor too well, leading to hypotony.

297 ngs are proposed to exist in doped water ice too, where IRs are even stronger.

298 antinociceptive action suggesting that they too would block this channel.

299 (1) received at least two doses of MCV; (2) too young for first dose; (3) received one dose but was

300 or first dose; (3) received one dose but was too young to receive the second; or (4) was only eligibl