ライフサイエンスコーパス: tool

1 fragment-based protein structure prediction tool.

2 putational scientists to easily navigate the tool.

3 py can be predicted with a molecular imaging tool.

4 an be significantly accelerated by using our tool.

5 thus represents an improvement over existing tools.

6 ) provides powerful dimensionality reduction tools.

7 and chemoprophylaxis are the most promising tools.

8 using UHPLC-HRMS and advanced data analysis tools.

9 o-inflation, which require tailored analytic tools.

10 r them as mainstream quantitative analytical tools.

11 ication paradigm and expansion of analytical tools.

12 with potential applications as gene-editing tools.

13 cases that remain difficult for text-mining tools.

14 ks of the plasmids to advanced bioinformatic tools.

15 tion via the implementation of semiclassical tools.

16 RD (AuROC for GERD, 0.579 vs range for other tools, 0.660-0.695), and predicted risk correlated well

17 ed to benchmarked open-access and commercial tools, achieving accuracy close to the expected level of

18 nstrated how process signatures from the PAT tools across various batches and campaigns can be analyz

19 cosystem services modeled with the web-based tool AguAAndes.

20 of PPARalpha with genetic or pharmacological tools ameliorates inflammation, vascular leakage, neurod

21 ative sum was 3.12 for competency assessment tool and 4.74 for global assessment score whereas laparo

22 3R agonist that may serve as both a research tool and a therapeutic lead for the treatment of neurops

23 erase Cps1B of App1 as an in vitro synthesis tool and an alternative for capsule polymer provision.

24 hlight key advantages and limitations of the tool and compare it to other peptide ligase enzymes.

25 of bias and study quality using the Cochrane tool and Scottish Intercollegiate Guidelines Network che

26 systems, have emerged as a biotechnological tool and therapeutic.

27 We have produced open-source tools and a public data set consisting of tumor/TIL maps

28 tive predictive value compared with existing tools and correctly identified >75% of HLA-bound peptide

29 ARESdb with state-of-the-art bioinformatics tools and curated public data.

30 Using a variety of genetic tools and epistasis experiments in P. putida, we uncover

31 alk with visible light excitable optogenetic tools and fluorescent probes, and decreased scattering a

32 d consumption, by linking Industrial Ecology tools and Integrated Assessment Models (IAM).

33 antitarget M(2) are valuable pharmacological tools and may enable improved treatment of chronic obstr

34 th ABCA4 variants using conventional genetic tools and next-generation sequencing technologies.

35 Tools and strategies to mitigate the extreme and multipl

36 e then discuss a suite of example management tools and their potential evolutionary implications-both

37 We present novel tools and workflows for the detection of different alter

38 tential of GB segregation as an alloy design tool, and enable the design of microstructures that maxi

39 d experiment, is adaptable as an educational tool, and provides insight on the possible coevolutionar

40 seling in clinical settings, review existing tools, and discuss opportunities and challenges for inte

41 is study, we leverage new mouse lines, viral tools, and molecular markers to better define GPe neuron

42 used in multiple modeling and visualization tools, and we also provide reference Application Program

43 These tools are especially powerful when deconvoluting highly

44 These tools are implemented in custom code and separate packag

45 These tools are more accurate than frequency and duration of G

46 Rapid and accurate diagnostic tools are needed for appropriate management of infectiou

47 Tools are needed to assess whether these drugs benefit p

48 , and major gaps have been identified in the tools available for the identification, and the hazard a

49 system, but there are very few bioinformatic tools available to interpret the results.

50 We develop a new tool based on a representation of HiChIP data centred on

51 magnitudes compared to the state-of-the-art tools based upon tabix.

52 t protein production has become an important tool, but is still rarely applied to engineer mammalian

53 atus Index (CONUT) are widely used screening tools, but their efficacy has not yet been compared in M

54 tperformed TRF and MISA-the most widely used tools-by 78 and 84%.

55 n together, our work highlights how low-cost tools can automatically quantify behavior in naturalisti

56 is review provides perspectives on how these tools can be applied to specific research fields such as

57 h immune interaction network upon which such tools can be built.

58 talizing on this knowledge, novel diagnostic tools can be developed to guide clinical diagnosis of co

59 Moreover, existing tools can not perform alignment of amino acid sequences,

60 y imaging (MSI) is an established analytical tool capable of defining and understanding complex tissu

61 bacteriophages hold great promise as medical tools, clinical applications have been limited by certai

62 Complementing these experimental tools, co-polymers theoretical methods are necessary to

63 development of new CRISPR-Cas genome editing tools continues to drive major advances in the life scie

64 State-of-the-art tools (DADA2 and Deblur) were far less accurate.

65 cture prediction and design corresponding to tools developed using our RNA-As-Graphs (RAG) approach.

66 There is concern, however, that these tools do not work equally well for all subgroups of the

67 ce are the most commonly reported analytical tools during dereplication analysis.

68 designed to validate the IBD Disk, a visual tool easily useable in daily practice to assess disabili

69 ddition to phenotype tools, genetic analysis tools enable users to integrate and interpret genome-phe

70 materials have been shown to be a promising tool, even transplanted in vivo, for transducing light s

71 In conclusion, here we present a simple tool, extensible to Orbitrap-based mass spectrometers, f

72 Many available tools facilitate analyses of one of the two major mechan

73 as a non-invasive diagnostic and prognostic tool for AD, regardless of clinical stage, which would b

74 may offer a complementary risk communication tool for AF in clinical practice.

75 nous whole blood) and that DBS is a suitable tool for assessing MeHg exposure in human population stu

76 In conclusion, we provide a tool for assessment of molecular subtypes of bladder can

77 h condition, developing simple models (and a tool for calculation) of excess COVID-19-related deaths,

78 ver a cost-effective and easy to use sensing tool for customized administration of drugs in Alzheimer

79 Mendelian randomization (MR) is a valuable tool for detecting causal effects by using genetic varia

80 ne ((18)F-FET) has been shown to be a useful tool for detecting TP and TRCs.

81 e X-ray spectroscopy (TEM-EDX) is a powerful tool for determining these particle characteristics, but

82 fficking in humans and its use as a research tool for diagnostic imaging of obesity/diabetes, bacteri

83 on scheme developed here provides a flexible tool for disease management planners which translates mo

84 nvision the current technology as a powerful tool for early warning and detection of low pathogen con

85 e AAV1 a promising anterograde transsynaptic tool for establishing a comprehensive cell-atlas of the

86 ing the polarity in molecules is a versatile tool for expanding the boundaries of structural space.

87 t and non-expert users, making it a powerful tool for gaining novel insights into genome evolution.

88 dic linkage, demonstrating the power of this tool for glycan analysis.

89 s spectrometry (IM-MS) has become a powerful tool for glycan structural characterization due to its a

90 S index (HOUSES) would serve as a predictive tool for graft failure in patients (n = 181) who receive

91 mass spectrometry (MALDI-MS) is an important tool for high-throughput N-glycan profiling and, upon us

92 that enables mass spectrometry as a valuable tool for HOS elucidation.

93 romatin regions has emerged as a widely used tool for identifying active regulatory elements in eukar

94 Mass spectrometry is the premier tool for identifying and quantifying protein phosphoryla

95 and shoot branching, providing a new genetic tool for increasing seed yield and biomass production in

96 or (S1PR), which has been used as a research tool for inhibiting immune cell trafficking.

97 3D structures, STAR3D has become a valuable tool for its unprecedented speed and accuracy.

98 reat promise for its application as a unique tool for manipulating input-defined cell populations and

99 Laser microsurgery is a powerful tool for neurobiology, used to ablate cells and sever ne

100 urther show that GATIR mice provide an ideal tool for noninvasive monitoring of Th2 polarization and

101 he tools was assessed: MiXCR was the fastest tool for number of sequences processed per unit of time.

102 ion offers a robust and minimally perturbing tool for obtaining such measurements.

103 We used a novel tool for quantitative, real-time assessment of endogenou

104 Here we present Merqury, a novel tool for reference-free assembly evaluation based on eff

105 sensitivity analysis (CSA) is a new probing tool for sampling sensitivities to chemistry parameters

106 Selenium NMR has become a standard tool for scaling the pai-accepting character of carbenes

107 microscopy (SICM) has emerged as a versatile tool for studies of interfaces in biology and materials

108 This symbiont-mediated RNAi approach is a tool for studying bee functional genomics and potentiall

109 e model of HEV infection provides a powerful tool for studying viral-host interactions that should fa

110 ighlight clobetasol as an important chemical tool for target validation.

111 EVM proved to be a promising tool for targeted EMB because of its sensitivity and spe

112 how that the hACE2 mouse would be a valuable tool for testing potential vaccines and therapeutics.

113 community with a fast and easily accessible tool for the analysis of LCRs with additional informatio

114 ion of such antibodies represents a powerful tool for the development of correlates of protection tha

115 our studies highlight the VidaL system as a tool for the precise chemical modification of cellular p

116 We also present a tool for the quantification of strains from metagenomic

117 demonstrate RadAR as a reliable and valuable tool for the radiomics community.

118 Our model should provide a helpful tool for the rational design of strand-displacement reac

119 as to develop and validate a risk prediction tool for trauma-induced coagulopathy (TIC), to support e

120 this Feature, we introduce 3D printing as a tool for use in research laboratories, bridging the gap

121 lecule localization microscopy is a powerful tool for visualizing subcellular structures, interaction

122 sibility of using the black soldier fly as a tool for waste valorization and feed production has prim

123 , and can potentially be used as a screening tool for WUE(plant) in sorghum.

124 e combined in a workflow called the Standard Tools for Acroporid Genotyping (STAG).

125 proaches, we offer diagnostic and validation tools for all relevant steps.

126 al slide scanning and a CNN model are robust tools for augmenting the conventional detection of intes

127 ons, which have recently emerged as powerful tools for building highly accurate PESs for relatively l

128 Yet, the paucity of reverse genetic tools for choanoflagellates has hampered direct tests of

129 We have seen new tools for collection of patient-centered outcomes follow

130 high-performance machine learning-based NER tools for concept recognition and trained our concept em

131 d that MAnorm2 clearly outperformed existing tools for differential ChIP-seq analysis, especially whe

132 ains a challenge due to the lack of specific tools for doing so.

133 the full potential of coagulation models as tools for drug development and personalized medicine.

134 efficiency) of different metagenome analysis tools for extracting the CDS content of a microbial comm

135 t and has also provided useful resources and tools for further functional characterization of the nic

136 opy number variation (CNV) are two important tools for genome evolution and sources for the creation

137 stands out here as one of the most powerful tools for investigating the interplay between the geneti

138 ets, which can subsequently be used in other tools for loop discovery.

139 us 1 (HSV-1) strain 129 (H129) are important tools for mapping neural circuit anatomic and functional

140 for eight species, and a suite of innovative tools for querying, analyzing and visualizing this data.

141 Here, using advanced tools for real-time visualization of native YAP and targ

142 Among all the global alignment tools for RNA 3D structures, STAR3D has become a valuabl

143 ted the previously developed PREDICT scoring tools for stratifying risk of IE, and the need for under

144 LDH-H, constitute promising pharmacological tools for the de novo design and identification of LDH t

145 Biomarkers have emerged as powerful tools for the diagnosis, prognosis, and prediction of tr

146 s regarding lipid peroxidation, experimental tools for the study of such processes, as well as the re

147 aggressive social interactions and provides tools for their manipulation.

148 Thus, novel, accurate and cost-effective tools for viral load monitoring become crucial to allow

149 However, available tools frequently ignore evolutionary relations among mic

150 Instead, novel tools from the field of machine learning can potentially

151 Several tools, from base-calling to genome assembly, were ported

152 al problem solving, we introduce the Virtual Tools game.

153 In addition to phenotype tools, genetic analysis tools enable users to integrate

154 With literature-guided causal inference tools, >300 site-specific signaling relations were mappe

155 The tool guided an MI-based conversation between coach and p

156 ent of novel data-driven functional analytic tools has enabled the derivation of individualized multi

157 Some tools have also incorporated the mirGFF3 format directly

158 In response, some tools have been augmented with spaced seeds, which are c

159 supplement of the database, several flexible tools have been developed to aid retrieval and analysis

160 ently, an array of powerful new neuroscience tools have provided unprecedented access to this elusive

161 We developed a novel, server-based tool (ICBM-OCEAN, Institute for Chemistry and Biology of

162 The NRS-2002, SGA, and CONUT tools identified nutritional risk in 67, 74, and 51% of

163 The HUNT, M-BERET, and Kunzmann tools identify patients with BE with AuROC values rangin

164 nt (CAREN) system as a visual rehabilitation tool in Argus II patients.

165 of chirality" has been proven as a powerful tool in asymmetric synthesis, while flow chemistry has b

166 MRI has become the most useful paraclinical tool in both situations and is used clinically to assess

167 Proteomics is an emerging tool in food authentication that has not been optimised

168 he described methodology could be a valuable tool in many areas of biological and medical research.

169 icle accelerators represent an indispensable tool in science and industry.

170 misinin-piperaquine as a malaria elimination tool in Southern Province.

171 Our study introduces DNA origami as a tool in the fight against antibiotic resistance, and our

172 Nanobodies are emerging tools in a variety of fields such as structural biology,

173 Among many accessible tools in diagnostic imaging, IVIM MRI aroused the intere

174 To this end, one of the primary tools in fluorescence microscopy is that of computationa

175 e widespread adoption of rapid diet screener tools in primary care and relevant specialty care preven

176 ass spectrometry is one of the most powerful tools in this context.

177 ht the utility of RNA sequencing and genetic tools in uncovering RGC type-specific roles during the d

178 Paired with diverse CRISPR tools including our dual fluorescence CRISPRi/a cell lin

179 Using a common measure of children's tool innovation, we describe how multiple cognitive mech

180 lenges for integrating a rapid diet screener tool into clinician workflows through the electronic hea

181 crofluidic systems have been limited as this tool is difficult to implement on the nanoliter or small

182 n of whole-genome sequencing as a diagnostic tool is leading to the profiling of drug resistance to i

183 This flexible tool is now part of routine sequencing analysis at the D

184 Among those tools is single-virus genomics, which yields sequenced r

185 However, these tools lack a comprehensive pipeline that includes both p

186 prediction error (RMSPE) than when using no tool (leaving sequencing errors uncorrected).

187 Tools like the ASCRS postrefractive IOL calculator are u

188 As a key variance partitioning tool, linear mixed models (LMMs) using genome-based rest

189 related resources, a lookup database and web tool linked to PEATmoss was implemented.

190 hopping, and walking long distances, but not tool manufacture.

191 This new tool may be of great value for the study of macrophage b

192 ehensive overview on the established genetic tools, methods and applications we highlight the current

193 tionally, we developed a command line Python tool, mirtop, to create and manage the mirGFF3 format.

194 ured by the malnutrition universal screening tool (MUST), CT derived body composition as measured by

195 biomedical research goals providing critical tools necessary to achieve an end to the global STIs epi

196 Mass spectrometry imaging is a powerful tool of increasing utility due to its ability to spatial

197 With 15 chemical elements, the tool offers high flexibility in formula attribution.

198 an optimized Cas9-AAV6-based genome editing tool platform for site-specific mutagenesis and integrat

199 be 10 straightforward writing tips-and a web tool, PubReCheck-guiding authors to help address the mos

200 ols, a command-line program containing three tools: Quality Control, Read Subsampling, and Read Filte

201 es and can select one of three DNA alignment tools, ranging from ultra-fast low-RAM k-mer-based datab

202 s on learning more about the use of existing tools rather than simply developing new ones.

203 antages and disadvantages, which makes viral tool selection paramount for properly designing and exec

204 Imaging is an extremely intriguing tool since it assumes a follow up to treatments to surve

205 tion of the novel NMR-based machine learning tool "Small Molecule Accurate Recognition Technology" (S

206 r immunotherapy with novel molecular imaging tools such as (89)Zr-Df-IAB22M2C for PET imaging is of p

207 Anatomic imaging tools such as echocardiography and cardiac CT or CT angi

208 2, was studied using different spectroscopic tools such as steady-state & time-resolved fluorescence

209 However, effective scRNA-seq quantification tools tailored for TEs are lacking, limiting our ability

210 te free and open-source/external scripts and tools, tailoring the workflow to the needs of the indivi

211 teomics Companion (SCPCompanion), a software tool that enables rapid evaluation of single-cell proteo

212 tice-based criteria of a rapid diet screener tool that supports valid and feasible diet assessment an

213 Here we present CNV Radar, a software tool that utilizes next-generation sequencing read depth

214 erent physiological limits, thus providing a tool that will allow decision-makers to evaluate the rel

215 s and that they complement each other, novel tools that accurately identify the hard-to-predict prote

216 hermore, there has not been a unified set of tools that allows deep and complete RNA structure analys

217 mpare the multiple mouse systems and genomic tools that are commonly used for in vivo screens to illu

218 n spatially extended environments, requiring tools that can bridge the gap between intracellular and

219 an innovative way to explore purely chemical tools that can direct and control cellular behavior.

220 In particular, we emphasize exploratory tools that can guide spatial sampling and highlight the

221 Chemical tools that detect active MALT1 have been reported, but s

222 The few simulation tools that exist scale poorly to large modern phylogenie

223 In this review, we discuss tools that have proven powerful in the investigation of

224 far from being understood since experimental tools that measure neural activity across this brainstem

225 ral circuits is greatly facilitated by viral tools that spread transsynaptically.

226 This prompted us to develop such a tool, the Angioedema Control Test (AECT).

227 The development of tools through which the ISR can be modulated promises to

228 , describing the key drivers and providing a tool to account for biases in models that use these data

229 n neurons, validating transfer learning as a tool to adapt the model to novel categories of axonal mo

230 in this setting because they are a powerful tool to analyze data with large number of predictors and

231 We built a tool to assess ocular surface frailty.

232 Laser has been proposed as an effective tool to assist in bacterial decontamination and modulati

233 An AI is a powerful tool to assist physicians in the diagnosis of skin lesio

234 l depletion by methyl-beta-cyclodextrin as a tool to describe the physiological role of cholesterol i

235 ar the glass transition provides a sensitive tool to detect thermodynamic regions characterized by in

236 (MUAC) is used as an independent diagnostic tool to detect wasting in children aged 6-59 mo.

237 that lecithin nanovesicles offer an elegant tool to efficiently deliver hydrophobic molecules to ani

238 ing and may provide a potential liquid-based tool to evaluate the immunosuppressive activity of intra

239 ng (HSI) is being explored in endoscopy as a tool to extract biochemical information that may improve

240 Thus, we introduce a live-cell imaging tool to facilitate in vivo studies of cell-cycle control

241 the first musculoskeletal direct collocation tool to handle kinematic constraints, which enable model

242 ppropriate bioinformatics, provides a robust tool to identify additional mutations to facilitate gene

243 sts that butyrate could be broadly used as a tool to increase growth of virus stocks for research and

244 Recently, feedback has been suggested as a tool to induce phase transitions beyond the dissipative

245 e genetics approaches represent an excellent tool to investigate the biology of TCRV and to explore i

246 c neurotransmission, thus making it a unique tool to investigate the brain and its complex neurocircu

247 ed actin has become the most widely employed tool to measure the kinetics of actin polymerization and

248 suggests that [(64)Cu]Cu-pHLIC is a valuable tool to noninvasively assess acidosis associated with bo

249 volatile fingerprints constitute a valuable tool to obtain insights on the impact of each brewing st

250 ected spin labeling (SDSL) ESR is a valuable tool to probe protein systems that are not amenable to c

251 olabeled exendin has proven to be a powerful tool to quantify beta-cell mass (BCM) in vivo.

252 rynebacterium RT-PCR method provides a rapid tool to screen isolates and identify probable diphtheria

253 Thus, the new mouse line is an ideal tool to study cytotoxic T lymphocyte biology and to opti

254 r overall integrity would be a very valuable tool to study functions of lipid asymmetry.

255 cible Cre recombinase system is an essential tool to study gene function when early ablation or overe

256 This novel system provides a powerful tool to study hepatocyte biology, disease mechanisms, ge

257 Passive acoustic monitoring is an efficient tool to study temporal variations in the occurrence and

258 Single cell sequencing has become a powerful tool to study the genome of individual cells for the det

259 y, this work provides practitioners with the tools to analyze proteins over a wide temperature range,

260 Here we apply modeling tools to better understand adaptive divergence of whitef

261 Appropriate tools to confront diphtheria exist; however, accurate un

262 x groups for all new artificial intelligence tools to ensure responsible use of artificial intelligen

263 splant recipients, and we used bioinformatic tools to evaluate protein abundance and functional categ

264 and a validated animal model of the disease, tools to facilitate vaccine development must be identifi

265 HBV screening strategies and the accuracy of tools to identify persons at increased risk.

266 hlights the potential benefit of diagnostics tools to identify S. aureus CC during bovine mastitis.

267 By using tools to improve statistical power in combination with o

268 ential of targeting PKC with pharmacological tools to inhibit pathologic fibrosis has not been fully

269 nforce the power of monoclonal antibodies as tools to interrogate structure-function relationships of

270 This work provides unique tools to modulate aGPCR-ligand binding and establishes a

271 Here, we present new tools to overcome these limitations.

272 rly course of treatment seem to be promising tools to predict the clinical response to vedolizumab th

273 Analytic tools to produce multi-locus genotypes of hosts based on

274 The lack of tools to reliably detect RanBP9 in vivo has significantl

275 t defined genomic sites and will be valuable tools to study DSB repair at a local and genome-wide sca

276 ates adaptation to new environments, but the tools to test its limits are lacking.

277 However, tools to track the systemic behaviour and dynamics of le

278 ed pseudo-NP libraries using chemoinformatic tools, to assess their molecular shape diversity and pro

279 tructural databases and fusion of prediction tools toward protein disorder characterization in health

280 edefined by the development of new molecular tools, tumour modelling systems and precise instrumentat

281 Second, we expand the taxonomic breadth of tool use to include another group of birds, seabirds, an

282 ectron microscopy (SEM), is the most popular tool used in nanotechnology and material science.

283 l coherence tomography (AS OCT) is a helpful tool used to diagnose and manage many corneal conditions

284 State-of-the-art tools used to probe connectivity with cell-type-specific

285 We suggest that tool-using NC crows offer highly useful data for current

286 In addition, run time of the tools was assessed: MiXCR was the fastest tool for numbe

287 In developing this tool, we integrated the transcript dataset of plants, se

288 Using genetic and chemical tools, we demonstrated that FACT is needed to overcome r

289 esearch spurring the emergence of innovative tools, we examine the design, synthesis, and properties

290 with annotations generated by three similar tools, we found that Binner achieves superior performanc

291 chniques, combined with electrophysiological tools, we revealed a population of glycinergic cells in

292 eveloping an experimental setup and analysis tools, we show that, within the whole system (beyond the

293 All of the tools were more accurate in identifying patients with BE

294 Furthermore, in silico tools were used to expand our chemical knowledge of comp

295 Furthermore, the data generated with these tools, when combined with advanced data science approach

296 tment is a potential non-invasive anti-tumor tool, which may have wide application for tumors located

297 ating these techniques into standard-of-care tools will transform patient stratification, disease mon

298 However, an easy-to-use lollipop-diagram tool with full functionality is still lacking.

299 Real-time PCR was used as a screening tool with great accuracy, while internal transcribed spa

300 ealth warning system is found to be a useful tool with reasonable skill to provide the climate-health