ライフサイエンスコーパス: torsional

1 e predominantly stereoelectronic rather than torsional.

2 ngth and a large positive Poisson's ratio on torsional actuation and electronic properties.

3 is-free tensile strokes of more than 30% and torsional actuation capable of spinning a paddle at spee

4 ally and experimentally shown to result from torsional actuation.

5 model shows that these observations resemble torsional Alfven waves associated with high frequency dr

6 l amplitude (R(2) = 0.7269, P = .01) and 80% torsional amplitude (R(2) = 0.6995, P = .02) but not at

7 cy with increasing longitudinal power at 60% torsional amplitude (R(2) = 0.7269, P = .01) and 80% tor

8 his difference is accounted for by increased torsional amplitude at the chain ends in bilayers, while

9 d cardiac MyBP-C relieved the restriction of torsional amplitude but also decreased the rate of torsi

10 was done using OZil IP at 60%, 80%, and 100% torsional amplitude with 0%, 10%, 20%, 30%, 50%, 75%, or

11 Baseline comparison of 60% or 80% vs 100% torsional amplitude without longitudinal power showed in

12 creasing phacoemulsification efficiencies at torsional amplitudes less than 100%.

13 ative dissipated energy and longitudinal and torsional amplitudes were found to be significantly lowe

14 s not further increase efficiency at maximal torsional amplitudes.

15 he efficiency difference between 60% vs 100% torsional amplitudes.

16 als is the results of the coupled effects of torsional and bending modes.

17 g the highly displaced, nontotally symmetric torsional and C(15)-H HOOP modes that appear because of

18 but also associated physical moduli, such as torsional and dilational rigidity, which correspond to t

19 The sensitive torsional and lateral modes enabled measurement of self-

20 w here novel cantilever designs that express torsional and lateral modes exhibit excellent mass-chang

21 More than a million torsional and tensile actuation cycles are demonstrated,

22 that provide fast, high-force, large-stroke torsional and tensile actuation.

23 nanotube yarns provide record performance as torsional and tensile artificial muscles, they are expen

24 der pure torsion as well as a combination of torsional and tensile loads using a coarse-grained compu

25 horizontal rectus EOMs contributes to novel torsional and vertical actions.

26 on advancement allows independent control of torsional and vertical components of the deviation, and

27 provide a unique example of synergy between torsional and vibronic modes and their drastic effects o

28 phene, the resulting SBT systems are planar (torsional angle <1 degrees ) and highly pi-conjugated.

29 ies indicate the potential importance of the torsional angle between the 1-phenyl "A" ring and 4-phen

30 he lowest triplet state at all values of the torsional angle between the allyl subunits.

31 2,2'-1,3 benzyloxy tether that restricts the torsional angle between the two naphthalene subunits alo

32 this stability, with induced changes in the torsional angle delta (C5'-C4'-C3'-O3) and phosphate-pho

33 d by conformational dynamics that impact the torsional angle distribution between the porphyrin-porph

34 ergy curve for the singlet state occurs at a torsional angle near 45 degrees , in contrast to previou

35 The analysis of the glycosidic torsional angles and the pair interaction energy between

36 In the solid state, the torsional angles around the C-C bonds between the four p

37 and 4 were obtained as BF(4)(-) salts, where torsional angles larger than 80 degrees were observed be

38 y 90%; and (ii) provide a set of (chi1/chi2) torsional angles that leads to optimal agreement between

39 1a-c provided quantitative bond lengths and torsional angles to support the conclusion that the down

40 that use of the provided set of (chi1/chi2) torsional angles together with other observables, such a

41 Then, we extracted torsional angles via the Bio3D module in R language.

42 The classification of torsional angles was also done in R according to the pen

43 ies, are the tools for classifying rotamers (torsional angles) in a way that reflect their frequency

44 s of fluctuations in backbone and side chain torsional angles, and averaged (1)H chemical shifts are

45 Given by chi torsional angles, rotamers describe the side-chain confo

46 liability of the provided set of (chi1/chi2) torsional angles, the side chains of all reported confor

47 e all included in the rate computations, and torsional anharmonicity effects on the density of states

48 ow the importance of multiple structures and torsional anharmonicity in determining the thermodynamic

49 Torsional artificial muscles generating fast, large-angl

50 This twist stability enables torsional artificial-muscle motors having improved perfo

51 tramolecular interactions of these molecular torsional balances were quantitatively measured via the

52 lts in a reduction of the N horizontal lineN torsional barrier and thus in accelerated thermal Z -->

53 Minimization of the torsional barrier for phenyl ring flipping in a metal-or

54 rmer via hydrogen-atom tunneling through the torsional barrier, which is also a unique observation fo

55 m our analyses, the trend observed for lower torsional barriers can be extrapolated to actual isomeri

56 ational diffusion, possibly reflecting lower torsional barriers, and demonstrate the power of transit

57 simulations by allowing significantly lower torsional barriers, but in no way compromising the atomi

58 s upon encountering mechanical, chemical and torsional barriers, sometimes stepping back and cleaving

59 feature of chromosome metabolism to overcome torsional barriers.

60 Here we investigate the torsional behavior of nucleosome arrays by means of Brow

61 m-sequence dsDNA in bending, stretching, and torsional behaviors; Z-DNA to be at least three-fold sti

62 n of meso-substituted side arms (with double-torsional biphenyl rings) of tetratopic porphyrin linker

63 Media viscosity, however, affects not only torsional but also vibrational modes.

64 ription factor GreB effectively enhances the torsional capacity of RNAP.

65 , the eccentric eye positions also involve a torsional component, which according to Donder's law is

66 ge to independent adjustment of vertical and torsional components.

67 upports a proposed linear "DNA crunching" or torsional compression motor mechanism involving a transi

68 MGB proteins constrain DNA winding, and this torsional constraint is released over short timescales.

69 To examine the effect of the torsional constraints imposed on DNA substrates on Cas9

70 vage efficiency of Cas9 drastically, whereas torsional constraints on the target strand had little ef

71 Mean torsional correction from preoperative to preadjustment

72 presenting concentric circle targets without torsional cues.

73 Finally, torsional data transformation such as the sum of angles

74 rmation after being subjected to tensile and torsional deformation.

75 While most torsional degrees of freedom in retinal are characterize

76 trongly enhanced coherences in low-frequency torsional degrees of freedom over the fingerprint region

77 Particular attention was paid to the torsional degrees of freedom that determine the shape of

78 g conformational search in the low-frequency torsional degrees of freedom.

79 The torsional dependence of donor-bridge-acceptor (D-B-A) el

80 The torsional dependence of the ground state magnetic exchan

81 The torsional dependence of the pairwise exchange interactio

82 ght bar from the earth-vertical exceeded the torsional deviation of the eyes, indicating that the per

83 onor was found to be in between that of the "torsional" disarmed and an armed donor.

84 sease prior to surgery, and myoclonic versus torsional disease phenotype had no significant effect on

85 s of nonconjugated ("kinetic") iminium ions, torsional distinction is small between the top- and bott

86 this article, we use our recently developed torsional-dynamics method called Generalized Newton-Eule

87 Torsional effects are largely responsible for the stereo

88 y observed for Z = OH and NH2, indicative of torsional effects as an important contributor in governi

89 tential of electronic, stereoelectronic, and torsional effects as tools to implement selectivity in C

90 nene derivatives are controlled primarily by torsional effects that also influence alkene pyramidaliz

91 Stereoselectivity is partially controlled by torsional effects, but for highly exo selective electroc

92 The torsional elastic coefficients determined from the simul

93 The effective torsional elastic constant is found to depend on the bin

94 tate Brownian ratchet using the asymmetry of torsional elastic energy of the coiled-coil gamma -shaft

95 Torsional, electrostatic, and steric effects can all inf

96 Supercoiled DNA polymer models for which the torsional energy depends on the total twist of molecules

97 chain has both modest barrier heights and a torsional energy surface that changes dramatically with

98 nical energy was converted proportionally to torsional energy.

99 ed, bond length inverted RPSB, and (3) rapid torsional evolution to the conical intersection after ov

100 Such torsional excitation is a form of parametric pumping in

101 ntal (conjugate and vergence), vertical, and torsional eye movements.

102 The modulation of vertical and torsional eye position was greater at 0.125 Hz while the

103 cating restriction of the amplitude of actin torsional flexibility by 15-20 degrees at saturation of

104 ng and torsional rigidities and intersubunit torsional flexibility measured experimentally with purif

105 transactivation in the yeast system and the torsional flexibility of target sequences were highly co

106 dapts to MeOH and H2 O guests because of the torsional flexibility of the main His-beta-Ala chain, wh

107 nnectivity and dimensions but quite distinct torsional flexibility.

108 We observe torsional flexing of the entire complex and a rotational

109 nset of elastic instabilities in viscometric torsional flows.

110 ole rings undergo simultaneous chi1 and chi2 torsional fluctuations at acidic pH, but only restricted

111 shifts of greater than two units arise from torsional fluctuations observed in molecular dynamics si

112 lets possessing rapid internal diffusion and torsional fluctuations.

113 Both stretching and torsional forces are considered, and these may be applie

114 As a proof of principle, we apply torsional forces to a coarse-grained continuum model of

115 well primed for ultrafast isomerization and torsional Franck-Condon analysis predicts a <200 fs P(fr

116 G and interfacial water while minimizing the torsional free energy.

117 o ligand series that differ by one degree of torsional freedom shows that the values of EM for the fl

118 CT, and CV were significantly smaller in the torsional group 1 day postoperatively (P = .002; P = .03

119 pated energy were significantly lower in the torsional group for harder nucleus density grades compar

120 ges at 1 day postoperatively in favor of the torsional group.

121 Our results suggest that the torsional interaction of RNAPs is an important mechanism

122 We conclude that conformational mutations by torsional interconversion of the three blades of the BCO

123 states of membrane proteins can be driven by torsional librations in the protein that may be coupled

124 The changes in glycosidic torsional linkage and the receptor conformations may alt

125 This study highlights the importance of torsional loading in axonal damage after traumatic brain

126 structure is consistent between uniaxial and torsional loading when the principal stress directions o

127 ity in general behavior between uniaxial and torsional loading, in spite of the implicit heterogeneou

128 t heterogeneous stress state associated with torsional loading, pointed to the ability of the reversi

129 mice increased the ductility of tibiae under torsional loading.

130 t Phaco torsional mode (Group 1) or combined torsional/longitudinal ultrasound mode (Group 2).

131 ore effective lens removal than the combined torsional/longitudinal ultrasound mode, with a lower cum

132 that would be well suited for analysis with torsional measurement techniques.

133 rs that electrochemically convert tensile or torsional mechanical energy into electrical energy witho

134 to assess the adaptability of LV strains and torsional mechanics during exercise in HCM patients.

135 The unimolecular torsional mechanism and isomerization through intermedia

136 To directly map the backbone torsional mobility in the varphi-psi dihedral angle spac

137 lsification using the OZil Intelligent Phaco torsional mode (Group 1) or combined torsional/longitudi

138 stretching coordinate into the reactive C-O torsional mode localized on the methoxy group four bonds

139 rture angled tip, the OZil Intelligent Phaco torsional mode provided more effective lens removal than

140 d significant anisotropy between bending and torsional moduli.

141 d using canonical DNA persistence length and torsional modulus values.

142 In this work, we show that torsional molecular dynamics simulations enhance protein

143 Torsional motility and junctional permeability to dextra

144 yne-allene isomerization involves not only a torsional motion but also a bending of the molecule due

145 mpede radical formation in PYP by preventing torsional motion in the electronic ground state of the c

146 Torsional motion is blocked when cadherins associate lat

147 Our data additionally suggest that torsional motion of chromophores about the molecular axi

148 pH-dependent conformational changes due to a torsional motion of its C-terminal domain.

149 electively show that T(c1) is related to the torsional motion of the N1 site, while T(c2) and T(c3) a

150 mers; pulling on this conformation induces a torsional motion perpendicular to the pulling direction

151 nal amplitude but also decreased the rate of torsional motion.

152 tous presence of high frequency ( 12-42 mHz) torsional motions in thin spicular-type structures in th

153 sphere and TR that are replete with twist or torsional motions on sub-arc second scales, occurring in

154 cles have been largely limited to bending or torsional motions or as tensile actuators with low work

155 sequence and establish RNAP as a more potent torsional motor than previously known.

156 Demonstrations include torsional motors, contractile muscles, and sensors that

157 capacitance change and electrically powered torsional muscles operating reversibly by a coupled tens

158 n time, compared with previous nanotube yarn torsional muscles, dynamic mirror positioning that is bo

159 alable, nonhysteretic, long-life tensile and torsional muscles.

160 and visually significant cataract underwent torsional (n = 26) or longitudinal (n = 26) phacoemulsif

161 A conformations based on a simplified pseudo-torsional notation of the RNA backbone, comparable to ph

162 ss, right gaze deviation, direction-changing torsional nystagmus, horizontal ophthalmoplegia, and gen

163 conversion of compressive displacements to torsional ones, was also proposed.

164 a multicavity optomechanical device in which torsional optomechanical motion can shuttle photons betw

165 asymmetry that induced expression of either torsional or lateral modes in the 0-80 kHz frequency ran

166 include a type of magnetic wave, known as a torsional oscillation, but recent studies favour periods

167 an (KC) reported a decrease in the period of torsional oscillators (TO) containing samples of solid (

168 Using multiple-frequency torsional oscillators, we can separate frequency-depende

169 equired, which provides superior charges and torsional parameters as compared to earlier alternatives

170 of superfluid helium-3 is studied using the torsional pendulum method.

171 in these cilium deformations by developing a torsional pendulum model of beat frequency dependence on

172 heory, including three-fold discrepancies in torsional persistence length at the high force limit and

173 Torsional phacoemulsification effectively reduces ultras

174 approximation (MS-QH) and also by including torsional potential anharmonicity (MS-T).

175 iences angular fluctuations in an asymmetric torsional potential, and a 'free' excited state in which

176 Multiple-structure anharmonicity, torsional-potential anharmonicity, and high-frequency-mo

177 Torsional power was set at 60% and intraocular pressure

178 We record and compare the torsional profiles of single Protein G-Immunoglobulin G

179 Predictions of the torsional profiles of the yet-unsynthesized bromo-, chlo

180 This region is essential to the torsional properties of the molecule as a whole because

181 Further blind predictions of helix torsional properties, however, exposed inaccuracies in c

182 mistically resolved level to investigate its torsional properties.

183 rly diastolic strain rate and LV torsion and torsional recoil rate were determined using cardiac magn

184 n time represents an intrinsic timescale for torsional relaxation and is independent of position, whi

185 that allowed us to discern the site-specific torsional relaxation at a low protein concentration unde

186 upon irradiation, relax via the nonradiative torsional relaxation pathway, and have been typically us

187 replicative catenanes, without causing their torsional relaxation.

188 Our results also explain the torsional resilience of chromatin, reconcile differences

189 We calculate the torsional resistance as a function of the rotation of th

190 strate dynamic nanotriboelectrification with torsional resonance (TR) mode atomic force microscopy (A

191 For comprehensive analysis, torsional resonators operating on three different modes

192 ase of operation, one might even replace the torsional resonators with thickness-shear resonators.

193 tions driven by torque, we have measured the torsional response of a panel of DNA sequences using sin

194 for quantitative predictions of the complex torsional response of arbitrary sequences in their biolo

195 imulations reveal a strong dependence of the torsional response on the rotational phase angle Psi0 be

196 he bound CR, in turn, is associated with the torsional restriction of this molecule upon binding.

197 ls reliably capture the filament bending and torsional rigidities and intersubunit torsional flexibil

198 lecule twisting experiments, suggesting that torsional rigidity increases when DNA is stretched.

199 The observed microscopic torsional rigidity of DNA is much lower than is measured

200 ts, including direct characterization of the torsional rigidity of strand-separated DNA, establish a

201 The torsional rigidity of the myosin-bound filament is also

202 ual environment with a series pitch, yaw and torsional (roll) rotations of their eyes, where each eye

203 yarns changes guest dimensions and generates torsional rotation and contraction of the yarn host.

204 eta-sheets, and observe a restriction of the torsional rotation of the CR molecule upon binding.

205 ities in both extensional (irrotational) and torsional (rotational) viscoelastic flows.

206 This activated the torsional, rotational vestibulo-ocular reflex, which exh

207 In this work, we demonstrate that the torsional rotations are used to actively enhance their a

208 des new detailed insight into the effects of torsional rotations which contribute to inhomogeneities

209 lexibility is driven thermally, from which a torsional spring constant of ~23 pN.nm/rad(2) is estimat

210 Using a statistical mechanics-based torsional spring model, we extracted values of the chrom

211 We report a method to profile the torsional spring properties of proteins as a function of

212 r vibrometry revealed that the lid acts as a torsional spring system, driven by rain drops.

213 with each other via damped translational and torsional springs, and with the environment via sliding

214 RNAP) must transcribe supercoiled DNA, whose torsional state is constantly changing, but how RNAP dea

215 ditive function of the number of well-folded torsional states (+/-55 degrees ) along the backbone.

216 they include a particular sequence of biaryl torsional states that causes excessive steric strain.

217 rise from alkene predistortion that leads to torsional steering in the transition states.

218 of the hydride attack was found to be due to torsional steering.

219 Both molecular systems show torsional stiffening for increasing rotation angle, but

220 The persistence length and torsional stiffness calculated from molecular dynamics s

221 the filament bending persistence length and torsional stiffness.

222 nergetic amide bond geometries influenced by torsional strain and H-bonding interactions.

223 wnstream DNA into the Pol II cleft, creating torsional strain and leading to DNA unwinding.

224 tween a staggered transition state with less torsional strain and unfavorable steric interactions wit

225 Steric interactions and torsional strain appeared to play a major role in contro

226 at type II topoisomerase-mediated release of torsional strain at chromosomal loop anchors generates D

227 In E. coli and SV40, the release of torsional strain by type II topoisomerases is critical f

228 DNA translocation and DNA torsional strain created near the entry site of nucleoso

229 l and computational studies suggest that the torsional strain effects arising from the presence of th

230 tivity while accounting for the influence of torsional strain in the genome.

231 Increase in torsional strain in the HAT transition state accounts in

232 is was rationalized by the drive to minimize torsional strain in the transition state being coupled w

233 GAP Arg85' side chain, but neither phosphate torsional strain nor general base catalysis is evident.

234 initial steps of the packaging reaction, the torsional strain of the genome is released by rotation o

235 rily by the differences in the structure and torsional strain of the substituted ketal groups in the

236 noncovalent interaction analysis reveal that torsional strain plays a major role in the preference fo

237 DNA under torsional strain undergoes a buckling transition that is

238 tructures (ADS) can be triggered by negative torsional strain, which occurs during replication and tr

239 Steric and torsional strains present in the trans isomer are respon

240 center of the recombination crossover site, torsional stress and salt concentration.

241 can have multiple bend locations under high torsional stress and that the positions of these sharp b

242 Topoisomerase II (TOP2) relieves torsional stress by forming transient cleavage complex i

243 Top1 relieves torsional stress by nicking and resealing one DNA strand

244 ormational distribution of minicircles under torsional stress can be designed, which has important im

245 and separation by transcription or increased torsional stress can expose these DNA regions to damage

246 ts we have found that enzymes that relax DNA torsional stress display rates that depend strongly on h

247 Cellular DNA is regularly subject to torsional stress during genomic processes, such as trans

248 erates transient nicks in the DNA to relieve torsional stress encountered during the cellular process

249 Topoisomerase II (TOP2) removes torsional stress from DNA and facilitates gene transcrip

250 activation, based on DNA nicking to relieve torsional stress from eRNA synthesis.

251 Torsional stress generated during DNA replication and tr

252 DNA strand and facilitating religation after torsional stress has been relieved.

253 However, under torsional stress imposed by active transcription, DNA ca

254 The resulting torsional stress in DNA can accumulate and, in the absen

255 Topoisomerase 1 (TOP1) relieves torsional stress in DNA during transcription and facilit

256 Increasing negative torsional stress in DNA enhances Satb1 binding and Satb1

257 Moreover, although the value of the torsional stress in each domain may vary, their differen

258 This behavior is attributed to torsional stress in gamma, arising from gammaalpha3beta3

259 s of the DNA double helix to accommodate the torsional stress injected in the molecule by topoisomera

260 distribution of DNA under various levels of torsional stress is an important unsolved problem.

261 ndent on DNA supercoiling: DNA with positive torsional stress is compacted more quickly than negative

262 l properties of chromatin fibers dictate how torsional stress is partitioned to minimize these risks

263 cktracking is the primary mechanism by which torsional stress limits transcription and that the trans

264 dinated action of BRD4 and TOP1 overcame the torsional stress opposing transcription as RNAPII commen

265 This torsional stress promotes the formation of plectonemic s

266 poisomerase I (Top1), an enzyme that removes torsional stress that accumulates when DNA strands are s

267 the virion into the T4SS channel, causing a torsional stress that breaks the mature F-pilus at the c

268 ane provokes the accumulation of tensile and torsional stress that ultimately leads to the rupture of

269 inding complementary DNA strands, generating torsional stress, and sensitizing the exposed single str

270 the GDH enzymatic activity. It introduces a torsional stress, and the associated rotational shift in

271 Due to torsional stress, duplex DNA can have local, sequence-de

272 ans to prevent histone loss upon exposure to torsional stress, thereby contributing to the integrity

273 led to an inability to sense and repair DNA torsional stress, which resulted in increased mutagenesi

274 ng differences in how the topoisomers handle torsional stress.

275 melted) state, within a given sequence under torsional stress.

276 nce-dependent mechanical instabilities under torsional stress.

277 the range of 100 bp are circularized without torsional stress.

278 growth, creating regional heterogeneity and torsional stress.

279 ion reactions are largely insensitive to DNA torsional stress.

280 D structure of a 336 bp DNA minicircle under torsional stress.

281 ion-rotation profiles, and suggest a role of torsional stresses in regulating chromatin assembly and

282 While the effects of torsional stresses on naked DNA have been well studied,

283 Type IB DNA topoisomerases can eliminate torsional stresses produced during replication and trans

284 ains all protein-DNA contacts but introduces torsional stresses that kink and undertwist the promoter

285 we have been able to control the bending and torsional stresses within a looped DNA construct.

286 his is relevant for bacterial cells in which torsional tension is maintained by enzyme-dependent home

287 l agarose gel electrophoresis to examine the torsional tension of replication intermediates of three

288 t maintain a supercoiled state with constant torsional tension.

289 We use torsional travelling waves to control the contact angles

290 the probe-target duplex, quenching caused by torsional twisting and dye-dye contact is prevented.

291 reveals both configurational defects such as torsional twisting, and strong symmetry breaking at the

292 to Col1a2(oim/+)sires had a 15% increase in torsional ultimate strength, a 29% increase in tensile s

293 tive dissipated energy, and longitudinal and torsional ultrasound amplitudes in Group 1 were 58.21+/-

294 mulative dissipated energy, longitudinal and torsional ultrasound amplitudes, mean operation time, me

295 tilt, which evokes ocular counter-rolling, a torsional vestibulo-ocular reflex (VOR).

296 ation of the two structures and the observed torsional vibration and supports the prediction that the

297 A torsional viscoelastic model with frictional dissipation

298 the tangent cylinder that may be a source of torsional waves inside the core.

299 s associated with superhelicity and with the torsional winding of the displaced DNA single strand aro

300 Scalability to provide constant volumetric torsional work capacity is demonstrated over a 10-fold c