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1 velopment, gametes are reprogramed to become totipotent.
2 ll (2C) embryos in which the blastomeres are totipotent.
3                      Most stem cells are not totipotent.
4 maintaining high rates of DNA synthesis, are totipotent.
5 osons/genes are transiently expressed in the totipotent 2-cell (2C) embryos.
6 itions, that is, conversion of the oocyte to totipotent 2-cell blastomeres, compaction, and blastocys
7  catabolism played a role in the exit of the totipotent 2C state.
8                       ESCs can also generate totipotent 2C-like cells and trophectodermal cells.
9 caste fate, and (e) breeding conflicts among totipotent adults.
10 tic marks, allow a somatic nucleus to become totipotent after transfer into an oocyte, a process term
11 o environmental mutagens and plant cells are totipotent, an understanding of RNR function in plants i
12                                              Totipotent and differentiated cells exhibited similar in
13               Whereas Oct3/4 is expressed in totipotent and pluripotent cells in the mouse life cycle
14 complexes are essential for formation of the totipotent and pluripotent cells of the early embryo.
15 to host embryos is the key feature of murine totipotent and pluripotent cells.
16                             As a result, the totipotent and pluripotent embryonic stages remain susce
17     This review delves into the hallmarks of totipotent and pluripotent stem cells, shedding light on
18 ns of epiblast cells in vitro in the form of totipotent and pluripotent stem cells, which not only de
19 1) Sox2(+) /Pax6(+) stem-like cells that are totipotent and self-renew over the long term, 2) Ascl1(+
20 esults identify how epigenetics restrict the totipotent and trophectoderm fate in mouse ESCs.
21 generally considered pluripotent rather than totipotent because of the failure to detect germline cel
22 red oocytes for optimal progression into the totipotent blastocysts.
23 on from terminally differentiated gametes to totipotent blastomeres, but the identity of transcriptio
24 milies, where all members are reproductively totipotent but offspring transiently forgo reproduction
25                This finding demonstrates the totipotent capacity of bryophytes, the ability of a cell
26 lation in oocytes(3), and TPRX1, a eutherian totipotent cell homeobox (ETCHbox) family transcription
27 to judge totipotency by evaluating candidate totipotent cell types in mice, including early blastomer
28 identical genetic template and from a single totipotent cell.
29 inner cell mass (ICM) are the descendants of totipotent cells and can differentiate into any cell typ
30                     Alternatively, pluri- or totipotent cells can lead to the formation of a complete
31                                              Totipotent cells have the ability to generate embryonic
32                                              Totipotent cells in early embryos are progenitors of all
33                                 We show that totipotent cells of the early mouse embryo have slow DNA
34 pring were produced following aggregation of totipotent cells of the four-cell embryos.
35  complex multicellular organisms from single totipotent cells.
36 scription factor associated with potentially totipotent cells.
37                    Thus, zebrafish achieve a totipotent chromatin state at ZGA through paternal genom
38 er zygotic genome activation (ZGA) underlies totipotent development.
39 blastocyst-like structures, indicating their totipotent developmental abilities.
40 ticellular organisms can be regenerated from totipotent differentiated somatic cell or nuclear founde
41 dynamically reprogrammed post-fertilisation: totipotent early mouse embryos display non-canonical, im
42 ay for the induction of erythroid cells from totipotent ectoderm of the embryo.
43 taining the molecular characteristics of the totipotent egg and early embryo.
44 nd SUMO2/3 jointly mediate the repression of totipotent elements.
45                              Generation of a totipotent embryo involves chromatin reorganization and
46 al and a naive paternal genome to generate a totipotent embryo.
47 h the differentiated oocyte transitions to a totipotent embryo.
48  the germ cells are reprogrammed to form the totipotent embryo.
49 friable embryogenic callus from which highly totipotent embryogenic suspension cultures could be esta
50                                              Totipotent embryonic stem (ES) cells are infected with a
51 the murine beta-globin locus was analyzed in totipotent embryonic stem cells and in differentiated ce
52     It was found that s-SHIP is expressed in totipotent embryonic stem cells to the exclusion of the
53  osteopontin enhancer, which is expressed in totipotent embryonic stem cells.
54 hese findings raise caution about the use of totipotent ESCs in cell transplantation therapy, because
55                     Genes activated in mouse totipotent F9 teratocarcinoma cells solely by activation
56 transcriptional gene regulation preserve the totipotent genome of germ cells through generations.
57               Higher eukaryotes must adapt a totipotent genome to specialized cell types with stable
58 ell tumors (GCTs) arise by transformation of totipotent germ cells.
59                                              Totipotent germline blastomeres in Caenorhabditis elegan
60 uires the engraftment of genetically altered totipotent hematopoietic stem cells (THSCs).
61 family of zinc finger proteins, expressed in totipotent hemopoietic cells as well as in myeloid proge
62 vidual, otherwise indistinguishable cells of totipotent human embryos, primordial germ cells, and sta
63  surrounded efforts to undertake research on totipotent human stem cells.
64 g chromatin repression and desolation of the totipotent identity.
65  systems evolved and the mechanisms by which totipotent larvae give rise to the alternative adult cas
66 pluripotent stem cells are reprogrammed into totipotent-like 2-cell-like cells (2CLCs).
67                                Subsequently, totipotent-like cells are established with variable robu
68 k the relative role of Dux and MERVL in ZGA, totipotent-like characteristics, and cell toxicity.
69 terestingly, a rare population of cells with totipotent-like potential, known as 2 cell (2C)-like cel
70 A catabolism promotes dedifferentiation to a totipotent-like state characterized by defects in RNAPII
71 tem cell (mESC) cultures, are in a transient totipotent-like state resembling that of 2C-stage embryo
72 hat fork speed underlies the transition to a totipotent-like state.
73  that TRF2 depletion in ES cells activates a totipotent-like two-cell-stage transcriptional program t
74                                          The totipotent mouse embryonic stem (ES) cell is known to di
75                           Differentiation of totipotent mouse embryonic stem (ES) cells to various ly
76                                          The totipotent nature of plant cells, coupled with the inabi
77  as a result of generation of GRP cells from totipotent neuroepithelial stem cells, of O2A/OPCs from
78 entage of adult or differentiated cells have totipotent nuclei, and a much higher percentage of cells
79 ese data suggest that the cell lines exhibit totipotent potential and that BMP4 can prime human PSCs
80 xtended pluripotent states harbour increased totipotent potential relative to conventional embryonic
81 ound tissue identity is first specified from totipotent precursor cells in the embryo.
82 allowing differentiated gametes to unleash a totipotent program following fertilization.
83 nion at fertilization, their genomes drive a totipotent program, giving rise to a complete embryo as
84                             The immortal and totipotent properties of the germ line depend on determi
85 irectly reprograms a stomatal precursor to a totipotent, somatic embryo founder cell.
86 ux drives a small percentage of cells into a totipotent state by expressing 2-cell-embryo-specific tr
87 n oocytes can reprogram somatic cells into a totipotent state enabling animal cloning through somatic
88 into the establishment and regulation of the totipotent state in mouse embryonic stem cells.
89                                   Why does a totipotent state linger within the inner cell mass of mo
90 pecific epigenetic features to establish the totipotent state of the embryo.
91 llowing the zygote to be reprogrammed into a totipotent state.
92  (SCNT) can reprogram a somatic nucleus to a totipotent state.
93 germ cells (PGCs) marks the beginning of the totipotent state.
94 nome activation that initiates a short-lived totipotent state.
95 w DNA replication features of an early, more totipotent state.
96 the importance of DNA demethylation roles in totipotent stem cell induction and a new and easy way to
97                          We propose that the totipotent stem cell state was shaped by the need to res
98                                The zygote, a totipotent stem cell, is crucial to the life cycle of se
99                                              Totipotent stem cells are transiently occurring in vivo
100                     Here, we tried to induce totipotent stem cells by mimicking DNA demethylation pat
101  research using human embryos as a source of totipotent stem cells can secure broad public support if
102                                              Totipotent stem cells have the potential to differentiat
103                                   Renewal of totipotent stem cells in the germline and cellular diffe
104 tem cells such as pluripotent stem cells and totipotent stem cells, but challenges remain to be overc
105 z1- or Rfz2-specific chimera leads, in these totipotent stem cells, to some differential activation o
106 rate the integration of a functional gene in totipotent stem cells.
107 Although DUX4 and Dux both activate an early totipotent transcriptional program, divergence of their
108 ements are transiently up-regulated in mouse totipotent two-cell (2C) embryos during major zygotic ge
109                       In mice, exit from the totipotent two-cell (2C) stage embryo requires silencing
110 cells (ESCs) that induces genes expressed in totipotent two-cell (2C) stage embryos and 2C-like cells
111 es, similar to what is seen with features of totipotent two-cell blastomeres.
112 wise conversion between pluripotent and rare totipotent two-cell embryo (2C)-like stem cell states.
113 ch acts together with eIF4A2 to restrict the totipotent two-cell transcription program in ESCs throug
114 rements accompany the transition from motile totipotent unicellular organisms to multicellular organi
115             During gastrulation, PGCs remain totipotent while surrounding cells in the vegetal mass b
116 te larval instars, the latter functioning as totipotent workers (linear development).
117  unique form of eusocial polyphenism in that totipotent workers can differentiate into either soldier
118 he transition from differentiated gametes to totipotent zygote are poorly understood.
119 transforms a differentiated germ cell into a totipotent zygote capable of somatic development.
120 ession is essential for the development of a totipotent zygote into an embryo with defined cell linea
121 ty to transition from differentiated cell to totipotent zygote is unknown.
122  mechanisms regulate the transition from the totipotent zygote to pluripotent primitive ectoderm cell
123 eprogrammed after fertilization to produce a totipotent zygote with the potential to generate a new o
124 ls, the gametes are reprogrammed to create a totipotent zygote, a process that involves de novo estab
125 yo transitions from a fertilized gamete to a totipotent zygote.
126 differentiation resembles development of the totipotent zygote.

 
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