ライフサイエンスコーパス: tough

1 tructural materials that are both strong and tough.

2 ause solving problems one at a time might be tough.

3 unctional materials that are both strong and tough.

4 ded nanostructures that are both precise and tough.

5 icone-polycarbonate-urethane and is soft but tough (~15 megapascal at a rupture strain of >2).

6 , we present a transparent, strong (26 MPa), tough (152 MJ m(-3)), stretchable, and conductive ionoge

7 In this study, a numerical simulation code (TOUGH 2) was used to investigate the potential for detec

8 eir synergy enables the bioadhesives to form tough adhesion on ex vivo human and porcine tissues and

9 e report a bioadhesive that can form instant tough adhesion on various wet dynamic tissues and can be

10 pletion of mobile ions creates a junction of tough adhesion, and the stretchability of the junction e

11 Here, we developed the Dental Tough Adhesive (DenTAl), a bioinspired adhesive patch wi

12 Tensile testing demonstrated that this dural tough adhesive (DTA) exhibited greater toughness with hi

13 ecular design roadmap for the development of tough adhesive surgical sealants.

14 Tough adhesives provide resistance against high debondin

15 Developing tough adhesives with superior strength and ductility is

16 strategy to fabricate configuration-editable tough aerogels enabled by transformable gel precursors.

17 Altogether, the resulting tough aerogels with special configuration through soft t

18 elastin, collagen and glycosaminoglycan; and tough and compliant mechanical properties.

19 Our NOE hydrogel is mechanically tough and could selectively facilitate the adhesion of e

20 They have high water content but are still tough and durable.

21 Interestingly, the tensile test reflects a tough and elastic material, in contrast to prior Cp-base

22 Intrinsically tough and elastic polymers are leveraged primarily by in

23 twork of liquid droplets and its utility for tough and fast-acting underwater adhesives.

24 ith similar morphologies consume an array of tough and hard foods-complicating dietary inferences of

25 ory, we present a design principle for ultra-tough and highly recyclable elastic vitrimers with a def

26 Cells encapsulated in the tough and printable hydrogel maintain high viability.

27 lized cells in the stratum corneum provide a tough and resilient framework for the intercellular lipi

28 sipation during deformation, thus creating a tough and robust material.

29 Mechanically tough and self-healable polymeric materials have found w

30 compatible hydrogel system that is extremely tough and stretchable and can be 3D printed into complex

31 Recent progress on highly tough and stretchable polymer networks has highlighted t

32 ion of LA with small fractions of ODO yields tough and transparent thermoplastics that have over 12x

33 namel from a fibrous composite to a complex, tough, and damage-tolerant coating on dentin.

34 dinarily strong, mollusk shells and bone are tough, and porcupine quills and feathers resist buckling

35 f transforming plastic waste into versatile, tough, and reversible adhesives offers a sustainable sol

36 e report a bioinspired design for versatile, tough, and reversible adhesives upcycled from consumer p

37 s fibers within the tooth, providing a hard, tough, and strong architecture that enables the organism

38 Developing versatile, tough, and sustainable adhesives that function effective

39 d to the skin via a couplant made of a soft, tough, antidehydrating, and bioadhesive hydrogel-elastom

40 transport of uroplakins that assemble into a tough apical plaque, one or more layers of intermediate

41 rials that are strong, ultralightweight, and tough are in demand for a range of applications, requiri

42 ead to networks that are up to nine times as tough as conventional analogs.

43 up to 48% energy damping, and are nearly as tough as fibers used for bulletproof vests.

44 han the parental silkworm silk fibers and as tough as native dragline spider silk fibers.

45 b steaks in good (i.e. tender) and bad (i.e. tough) based on WBSF values and sensory scores with over

46 t strategies for optimizing architecture for tough bimaterial attachments in medicine and engineering

47 Polymer chain-based bioadhesives can form tough bioadhesion but remain vulnerable to fatigue fract

48 Tough bioadhesion stems from the synergistic contributio

49 urther research opportunities for developing tough bioadhesive surgical sealants are highlighted.

50 In addition, tough bioadhesives are emerging for efficient and physic

51 that integrate microstructured adhesives and tough bioadhesives, the soft climbing robot could achiev

52 e designed, synthesized, and characterized a tough biodegradable elastomer from biocompatible monomer

53 There is a significant medical need for tough biodegradable polymer adhesives that can adapt to

54 we demonstrate the development of stiff and tough biohybrid composites by combining collagen with a

55 till plenty of room mimicking the strong and tough biological designs at the multilength and time sca

56 relatively small compared to prototypically tough biological materials, like nacre.

57 sforming brittle materials into mechanically tough blends.

58 Hybrid systems of hydrogels and metals with tough bonding may find widespread applications.

59 Spider silk is tough, but becomes soft when exposed to water.

60 Cone scale xylem in flexing species is tough, but poorly conductive.

61 The tough C. elegans cuticle makes it challenging to extract

62 Furthermore, the potential difficulties and tough challenges that can impede their large-scale comme

63 development of therapeutic phages also faces tough challenges, such as laborious screening and time t

64 Here, we explore the tough choices oncologists face - not just which drugs to

65 is complex biomineral, and paves the way for tough coatings fabricated from cheap abundant materials.

66 ional academic laboratory during the current tough, competitive times.

67 f lightweight cellular materials, strong and tough composites, soft robots and autonomously shaping s

68 r, high concentration of emitters, and under tough conditions.

69 h-melting, thermally stable and mechanically tough copolymers, and a full range of polyolefin-like pr

70 nd bond to the silk fibre surface to produce tough, custom-shaped, flexible and electrically conducti

71 these reasons, the development of strong and tough (damage-tolerant) materials has traditionally been

72 Tough decoy (TuD) inhibition of miRNA-29c-3p in the mous

73 -encoded shRNAs via codelivery of inhibitory tough decoy (TuD) RNAs.

74 Analyses of tough decoy abundance in hepatocyte genomic DNA and inpu

75 dexamethasone, inhibition of miR-433 using a tough decoy altered the period and amplitude of Per2 gen

76 cted plasmid pools encoding more than 30,000 tough decoy miRNA inhibitors (hairpin nucleic acids desi

77 ction of adeno-associated virus expressing a Tough-Decoy targeting miR-26a prevents Smad down-regulat

78 -associated virus (rAAV) vectors with miRNA 'tough decoys' (TuDs) to inhibit specific miRNAs.

79 miR-26a by antisense oligonucleotides or by Tough-Decoys delays differentiation.

80 Tough developmental gains will be undermined in this cas

81 We tagged soft and tough double-network elastomers with mechanofluorescent

82 Here, we developed a tough double-network hydrogel (bio)ink for microfluidic

83 led the material from a thermoplastic into a tough elastomer with the tensile properties of high-valu

84 viscoelastic nanoparticle suspensions toward tough elastomers via Digital Light Synthesis (DLS) (an i

85 ance for rational design of high-performance tough elastomers.

86 Lightweight and tough engineered materials are often designed with three

87 Strain mapping reveals that the onion's tough epidermis acts as a barrier to fracture, enabling

88 Strong and tough epoxy composites are developed using a less-studie

89 f about 70 per cent but are still strong and tough, even when used for over one million cycles per ye

90 s of terrestrial insects in nature, obtain a tough exoskeleton through the activity of an ancient bac

91 that enable soft corals to survive without a tough exterior skeleton, and, until now, their biosynthe

92 al adhesive contacts before being drawn into tough fibers that rapidly solidify underwater to span ga

93 sonable approaches, we believe that, even in tough fiscal times, the main drivers of cardiovascular e

94 ing their soft and tough flesh-including the tough flesh of juvenile mammoths.

95 open-country prey, consuming their soft and tough flesh-including the tough flesh of juvenile mammot

96 muscle volume-assists with the processing of tough food items in tapirs and may yield similar benefit

97 This suggests that A. africanus ate more tough foods and P. robustus consumed more hard and britt

98 MTA) reveals that H. serum consumed soft and tough foods, similar to the extant cheetah, which active

99 of tendon and cartilage to bone is extremely tough (for example, interfacial toughness approximately

100 a facile and scalable method of fabricating tough, freestanding membranes that combine the best attr

101 It is shown that a strong and tough glass can be fabricated through a direct-solidific

102 ks between polymer chains to render a stiff, tough, glassy, and homogeneous network (that is, no phas

103 rpolymer interaction is the key to forming a tough, healable, elastomeric material.

104 trations, the nanowhisker glue paired with a tough hydrogel achieves an interfacial fatigue threshold

105 3D-printed structures of the tough hydrogel can sustain high mechanical loads and def

106 The tough hydrogel consisted of energy-dissipative ionically

107 By adding biocompatible nanoclay, the tough hydrogel is 3D printed in various shapes without r

108 A 3D printable and highly stretchable tough hydrogel is developed by combining poly(ethylene g

109 f cationic polymers interpenetrated within a tough hydrogel matrix.

110 Here, we apply a mechanically tough hydrogel paired with a bioadhesive for intraoperat

111 ed to wet tissues, the bioadhesive becomes a tough hydrogel with mechanical compliance and stretchabi

112 A new type of "rigid and tough" hydrogel with excellent elasticity is designed by

113 is generally applicable to various types of tough hydrogels and diverse commonly used elastomers inc

114 es that compare favourably to those of other tough hydrogels and even natural tendons; for example, a

115 Tough hydrogels are promising for soft robotics, bioelec

116 The use of tough hydrogels as biomaterials is limited as a conseque

117 ed saline, and cell culture medium to afford tough hydrogels capable of withstanding >90% compressive

118 cal properties, we report strong, stiff, and tough hydrogels composed of fiber-shaped elements that c

119 to anchor the long-chain polymer networks of tough hydrogels covalently to non-porous solid surfaces,

120 A core-clad fiber made of elastic, tough hydrogels is highly stretchable while guiding ligh

121 Triggerable tough hydrogels may be applied in myriad of applications

122 ely demonstrate the potential of triggerable tough hydrogels to serve as prolonged gastric resident d

123 roach allows simple synthesis of elastic and tough hydrogels with a well-defined structure and tuneab

124 The cumulative result is a series of tough hydrogels with tunable mechanical properties and t

125 onventional ice-templated and top-performing tough hydrogels, including high tensile properties, isot

126 scribe a novel set of materials, triggerable tough hydrogels, meeting all these requirement, supporte

127 abling injectability and cytcompatibility of tough hydrogels.

128 eir ability to anchor the highly elastic and tough IF cytoskeleton endowed vertebrates with robust ti

129 observations could be applied in developing tough, impact- and crush-resistant materials for joining

130 m and elastic substrate after unloading, the tough interface layer helped maintain bonding and except

131 approximately 800 J m(-2); refs ,), yet such tough interfaces have not been achieved between syntheti

132 t pressure in a sealed porcine aorta), makes tough (interfacial toughness of 150-300 J m(-2)) and str

133 Nacre, or mother-of-pearl, the tough, iridescent biomineral lining the inner side of so

134 , a potential solution to fully address this tough issue is reported by developing a super-antifoulin

135 ve complex, pitted surface textures, whereas tough leaves and meat more often leave anisotropic ones

136 which provide a pathway to making strong and tough lightweight materials.

137 e is very successful in designing strong and tough, lightweight materials.

138 wood' and can guide the biomimetic design of tough, lightweight structures.

139 ation of smoothly curving single crystals or tough, lightweight, self-repairing skeletal elements.

140 design of the next generation of strong and tough materials demanded by technologies as diverse as h

141 Many soft, tough materials have emerged in recent years, paving the

142 However, designing tough materials that are simultaneously strong and soft

143 to achieve mechanically compliant and ultra-tough materials.

144 y, binding the nanoparticles into strong and tough materials.

145 acity drug depot and combining a dissipative tough matrix on one side and a chitosan adhesive surface

146 high stress-carrying hard NTE phase and the tough matrix synergistically contribute to the high mech

147 d into two experimental groups: animals with tough meat (TO) and animals with tender meat (TE).

148 l to improve the organoleptic quality of the tough meat cuts.

149 ragility fractures represent an increasingly tough medical challenge, and the current treatment optio

150 The rational design of tough metallic glasses, however, remains challenging bec

151 een those of brittle ceramics and marginally tough metals.

152 hermore, a supercapacitor based on our super-tough MXene-functionalized graphene sheets provides a co

153 ntese breed classified as tender (n = 5) and tough (n = 5) meat were evaluated using SWATH-MS and bio

154 will have implications in the development of tough nanostructured metals for forming operations and h

155 Strong and tough natural composites such as bone, silk or nacre are

156 This work shows tough natural silk fibres and strong synthetic fibres ca

157 lly because of the fibrotic and mechanically tough nature of this tissue.

158 Simultaneously hard and tough nitride ceramics open new venues for a variety of

159 al axis (the rachis) of the wild-type into a tough, non-brittle form that promoted grain retention.

160 ture-sensitive ion channel gating has been a tough nut to crack.

161 an appressorium, which is used to breach the tough outer cuticle of a rice leaf, enabling the fungus

162 on cells called appressoria to penetrate the tough outer cuticle of the rice plant Oryza sativa.

163 ucture for virtually all bacteria, forming a tough outer shell that protects the cell from damage and

164 ebrates with the greatest capacity to reduce tough plant foods orally are also the most abundant and

165 We propose that the capacity to comminute tough plant foods was critical to the diversification of

166 ly, creating coarse surfaces for pulverizing tough plants and liberating nutrients.

167 Creation of strong and tough plastics from sustainable and biorenewable resourc

168 c PHA copolymers that are hard, ductile, and tough plastics, and exhibit polyolefin-like thermal and

169 f alternating refractive index surrounding a tough polymer core.

170 Tough polymeric photodetecting fibres drawn from a prefo

171 es the ability of fishes to process hard and tough prey.

172 A major challenge in synthesizing strong and tough protein fibers based on spider silk motifs is unde

173 chemically cross-linked, highly elastic and tough protein hydrogel using a mechanically extremely la

174 formed by Bacillus subtilis are encased in a tough protein shell known as the coat, which consists of

175 rful to discover something new and to tackle tough puzzles.

176 However, most hydrogels are insufficiently tough, release drugs in bursts, and require cell infiltr

177 Herein, we report the synthesis of ultra-tough, reprocessable elastomers based on linear alternat

178 lands face a myriad of problems that present tough research, management, and policy challenges.

179 Here, we report a design of tough reversible/recyclable adhesive materials enabled b

180 owever, coherent strategies for mechanically tough self-healing polymers are still lacking due to a t

181 sights into the design of coordination-based tough self-healing polymers.

182 ite general and should enable development of tough, self-healing polymers of practical usage.

183 that incorporates a biocompatible multilayer tough shell and an alginate-based core.

184 it is suggested that water quality in the V-tough should be checked more frequently in commercial la

185 orta to three-dimensionally (3D) print soft, tough silicone composites with an excellent combination

186 s, so-called spidroins, into extraordinarily tough silk fibers.

187 The filaments are extensible, strong and tough similar to natural silk and superior to the synthe

188 ides guidance toward the design of extremely tough soft composites.

189 Tough soft materials such as multiple network elastomers

190 The material is a tough solid at room temperature and below with mechanica

191 inks to prepare a class of highly strong and tough SPNs.

192 One of these was a tough sporopollenin wall that enclosed reproductive prop

193 Strong, tough, stretchable, and self-adhesive hydrogels are desi

194 hanical properties including being extremely tough, strong, resilient, adhesive, and fatigue-resistan

195 ing diffuse and complex fracture patterns in tough structural composites is at last beginning to yiel

196 well recognized as light-weight, strong, and tough structural materials.

197 eveals transferable principles for designing tough structures.

198 (2.5 mol%), yields extremely stretchable and tough supramolecular polymer networks, exhibiting remark

199 s, with fever and cough being most frequent; tough symptoms vary by SARS-CoV-2 variant and age.

200 mall group of clinical trials, including the Tough Talks for COVID-19 vaccine (TT-C) digital health i

201 2) O into carbon-based fuel by IR light is a tough task.

202 Too much dehydration resulted in tough textures and unacceptable sensory qualities for pr

203 Here we report that TOUGH (TGH) is a component of the DCL1-HYL1-SERRATE comp

204 n between MTA and both RNA Polymerase II and TOUGH (TGH), a plant protein needed for early steps of m

205 ng from rigid to flexible thermoplastics, to tough thermoplastic elastomers, to a pressure-sensitive

206 ng carbon nanotube electrical components and tough thermoplastic elastomers.

207 ur efficient polymerization method affords a tough thermoplastic that can undergo selective depolymer

208 ed from synthetic polymers can be strong and tough, they do not have the desired bioactivity for emer

209 scle by surrounding strong fibers with soft, tough tissue for protection and support.

210 t be flexible to wrap around vegetation, but tough to knock down trees and resist attack.

211 Although, as Yogi Berra said, "It's tough to make predictions, especially about the future,"

212 life is from the words of Yogi Berra: "It's tough to make predictions, especially about the future."

213 It is becoming increasingly tough to treat because of emergence of antibiotic resist

214 Here, we report a strategy to design tough transparent and conductive bonding of synthetic hy

215 an optical waveguide, in combination with a tough, transparent, and autonomously self-healing polyur

216 technologies have low efficiency and require tough treatment such as high temperature (>200 degrees C

217 may represent adaptation towards exploiting tough vegetation, suggesting cranial function and dietar

218 The strategy is to synthesize tough viscoelastic matrices from acrylate monomers in th

219 mniLyse device was found to effectively lyse tough-walled organisms in a very small, disposable, batt

220 This tough, waterproof layer is essential for maintaining the

221 d hearing loss is highly variable: some have tough, whereas others have tender ears.

222 ale) and about 10(4)-fold more biophysically tough, while retaining a clonal multicellular life cycle

223 nables a hybrid "dry" elastomer that is very tough with fracture energy 13500 Jm(-2) comparable to th

224 icrostructured composites that are stiff and tough with high sample efficiency.

225 ured bioadhesives, formed with a macroporous tough xerogel infused with functional liquids.