ライフサイエンスコーパス: towards

1 at was concomitant with enhanced sensitivity towards 2-deoxyglucose, an inhibitor of glycolysis.

2 ntaining DHTKD1 displaying improved kinetics towards 2-oxoadipic acid.

3 t have regenerative deficits and are shifted towards a de-differentiated state.

4 This demonstration is a first step towards a full cryogenic memory architecture targeting e

5 e needed to confirm the nonsignificant trend towards a lower graft survival in CMV high-risk patients

6 t changes in the characteristics of patients towards a lower risk phenotype were observed, particular

7 genome of neoplasms and other disease models towards a more 'normal-like state', having characteristi

8 Together, these recent findings point towards a more nuanced view of STM in which multiple sub

9 model advances current tumor invasion assays towards a more physiologically realistic model using tum

10 ly preserving ciliary structure and function towards a normal phenotype.

11 electron spins in silicon have made progress towards a platform that can be operated at higher temper

12 promotes allograft tolerance while immunity towards a range of pathogenic microbes is maintained.

13 irecting the functionality of the perovskite towards a solid-state electrolyte with electrochemical s

14 speakers and are asked to orient their head towards a sound source.

15 n of several mitochondrial genes, suggesting towards a specific role of AtPam16L in maintaining mitoc

16 However, most proposed solutions evolve towards a target geometry without considering time-depen

17 or frequent decentralized testing of I and C towards a tighter glycemic control and improved manageme

18 CMV infects, HCMV drives hematopoietic cells towards a weaker immune-responsive monocyte state and th

19 a-homologue Eip75B drives ISC daughter cells towards absorptive enterocyte lineage ensuring epithelia

20 us compounds, and innovative academic routes towards accessing these same products in a more sustaina

21 ving with HIV, and make substantial progress towards achieving 90-90-90 in a relatively short period.

22 bility by glycan repositioning may be a step towards achieving cross-group influenza protection.

23 defect engineering, down to a single defect, towards achieving the smallest memristor for application

24 ction, which was overcome before progressing towards action initiation.

25 on molecular and nanoengineering approaches towards activatable cancer immunotherapy.

26 rd based on full chart abstraction, pointing towards additional efficiency in the abstraction process

27 gle-crystal electrode surfaces is a key step towards addressing catalyst poisoning mechanisms in fuel

28 e systems optimised for single measurements, towards affordable and reconfigurable multi-measurement

29 The response of the chemosensor HMBP towards Al(3+) was attributed to the strategies of block

30 d by a robust proofreading activity of ThrRS towards Ala-tRNAThr.

31 ective: A high level of IgE cross-reactivity towards allergens from the birch homologous group has be

32 (ELISA) to establish a nanozyme-based ELISA towards alpha-lactalbumin (allergenic protein).

33 type of comparison and study quality, points towards an association between sustaining a sport-relate

34 teria, summarizes the challenges in the path towards an efficient strain construction and highlights

35 eins that modulate the vector gut microbiota towards an environment that favours colonization by the

36 orientation of phenolic compounds from algae towards an industrial application.

37 eshaping the proteome landscape of the cells towards an islet-like signature.

38 proves phenotype switching of TAMs from pro- towards anti-tumor expression in vitro.

39 on Knowledge, Attitudes, and Practices (KAP) towards antibiotics' use by adults, but none of these qu

40 ally relevant levels (ng/ml), paving the way towards applications in large multi-panel assays.

41 ntration increases significantly from summer towards autumn, possibly linked to the ocean freeze-up a

42 clear receptors that promote differentiation towards beta-catenin, a driver of proliferation and colo

43 uding systematic review specialists, to work towards better evidence syntheses for better evidence an

44 lase was associated with a significant shift towards better functional outcome (adjusted common OR 1.

45 st of our knowledge, both the developed MIPs towards BMK and the electrochemical sensor for its detec

46 Here, we discuss progress towards bridging the gap between climate science and pub

47 istic modelling systems can enhance progress towards capturing the physiological controls for phyloge

48 ate and an impaired ability to differentiate towards cardiac mesoderm.

49 Our technique paves the way towards characterising molecules in terms of their charg

50 ively filters small-molecule RyR1 modulators towards clinical relevance.

51 nregulating miR-21 and establishes a roadmap towards clinical translation of modulating miRs for vari

52 for this, and their potential to contribute towards clinically useful prediction techniques.

53 A tendency towards clustering of positive IOD events is evident in

54 y be intrinsically more active and selective towards CO(2) conversion than the bulk heterogeneous mat

55 ation of CTCF motifs presents the N-terminus towards cohesin as it translocates from the interior of

56 epts and carbon-derived battery technologies towards commercial implementation.

57 pative Kerr solitons, providing a first step towards connecting semiconductor ring lasers and microre

58 g feature selection methodologies are biased towards considering only one out of multiple biological

59 ensembles of atoms(4,8,9) and paves the way towards controlling many-body physics with light(5,6,11)

60 poiled food item leads to a lasting aversion towards cues reminiscent of the item.

61 le or reversibly covalent binding mechanisms towards cysteine thiols and other amino acids.

62 levation in Brown Norway rats showed a trend towards decreased expression of ATP5H.

63 the probability distribution of transitions towards decreasing order.

64 symmetry breaking, providing a general route towards designing versatile nanostructures.

65 Fungal culture was focused towards detection of filamentous fungi from sputum sampl

66 ified biosensor also offered its credibility towards detection of MP in vegetable samples with recove

67 These findings are a step towards developing a panel of genetic markers assessing

68 The research trends are also moving towards developing more eco-friendly formulations.

69 ts may turn out to be of immense consequence towards developing novel point-of-care hematological ana

70 Although selection towards different optima means that membership of ecolog

71 This study provides a major step towards direct quantitative radiation dose imaging in hu

72 Funding of research towards early diagnosis of PDAC has decreased by 19% sin

73 s showed IFNgamma secretion and cytotoxicity towards EBV-LMP2-expressing malignant cell-lines.

74 tivation results in enhanced differentiation towards effector cells, glycolysis and apoptosis.

75 workup choices, the process can be directed towards either tin- or iodo-substituted product formatio

76 ely to be of most impact in driving advances towards elimination targets at a population level.

77 ease burden, a necessary step in the pathway towards elimination.

78 Our work marks an important step towards enabling application-specific analog computing p

79 h-performance devices suggests a new pathway towards enabling high-resolution 3D imaging and inspires

80 superconductivity in TBG and open up avenues towards engineering quantum phases in moire systems.

81 Local adaptation directs populations towards environment-specific fitness maxima through acqu

82 ffect was greatest when participants reached towards (Experiment 1) or with (Experiment 3) the displa

83 Our findings open a path towards exploration of higher-dimensional topological ph

84 icant enhancement of the composite stability towards exposure to ambient conditions, up to 20 days.

85 tetrahedral Co(II) center, which is reactive towards external substrates including dioxygen.

86 Towards filling this gap, we performed a combined analys

87 nd expensive-and ongoing research is focused towards finding cheaper alternatives.

88 n nanomedicine serves to reinforce our drive towards further expanding and growing the maturity of na

89 with abundant hydrocarbons, and maps a route towards future catalytic systems.

90 intervention could help accelerate progress towards gender equality and combating HIV/AIDS.

91 on enables nanodisplay of diverse symmetries towards generation of potent vaccines.

92 taining dye 'coomassie brilliant blue' (CBB) towards GMP.

93 umbidgee, Macintyre) experience step changes towards greater discontinuity, characterised by pronounc

94 s of the aggregate-level data showed a trend towards greater shared environmental variation of height

95 ls in the blood Collectively, our data point towards haemoglobin scavenging of nitric oxide as a key

96 for these molecules and represent a key step towards high-precision studies in these systems.

97 ses on newly emerged enhanced SPR biosensors towards high-throughput and ultrasensitive screening of

98 increase in mean insulin levels and a trend towards higher C-peptide levels.

99 ized the area of point-of-care (POC) testing towards highly sensitive and selective quantification of

100 s and enhance PRC1 ubiquitin ligase activity towards histone H2A.

101 organic, organic and silicon-based materials towards hybrid organic-inorganic materials to develop in

102 atient and healthcare professional attitudes towards IBS.

103 These results justify policy change towards imminent death donation.

104 e have considerable potential to be utilized towards immunotherapy in synucleinopathies and may also

105 ow these tumours remodel the neuronal milieu towards increased activity are unknown.

106 past 30 years were characterized by a trend towards increased authorship by women, with new author p

107 nter snowfall patterns, and there is a trend towards increasing winter snow in semi-arid regions in C

108 by a transition in hand use, from locomotion towards increasingly dexterous manipulation, concomitant

109 ed in tissue barrier fitness are predisposed towards inflammatory diseases, but most do not develop o

110 ast majority of private funds are redirected towards influencing the prescription behaviour of practi

111 -beta, with a ~200 residue linker, is biased towards inhibitory autophosphorylation.

112 r several decades, and focus is now shifting towards investigating multispecies biofilm communities r

113 energetic investment in many small offspring towards investing less total energy into fewer, better p

114 minimize tilting a visually symmetric object towards its concealed asymmetric center of mass (CoM), b

115 der parameter fluctuations shifts the system towards its critical point.

116 tion, and substantial progress has been made towards its high-resolution characterization.

117 ro-inflammatory cytokine production, a shift towards ketone bodies as the metabolic substrate for the

118 A modulated bi-phase synthesis towards large-scale manganese 1,4-benzenedicarboxylate (

119 The work also constitutes an important step towards large-scale quantum dot simulators of correlated

120 e performance of EUS in 6-12 months directed towards lesions determined to be low risk (by a multidis

121 ce compositions of the two lava units change towards less radiogenic Nd, Hf, and Pb isotope ratios.

122 robust in this sub-group, and opens the path towards leveraging HEAs as functional waste forms for a

123 Wolves and bears were also attracted towards LFs, whereas prey species avoided them.

124 RAS-dependent regulation of HSL biases cells towards lipid storage for subsequent utilization during

125 rients, motile bacteria can actively migrate towards locations of richer resources.

126 ansporter activity reduces migration of GSCs towards low concentrations of S1P in vitro In addition,

127 LA2) or lipoxygenase (Lox) blocks chemotaxis towards low concentrations of S1P.

128 reflects community-wide compositional shifts towards lower ecological diversity, but the extent and d

129 This work is an important step towards making physical simulations of biological proces

130 are generated as oncogenic lesions progress towards malignancy, which we computationally predict wil

131 on of glucose to fructose is a critical step towards manufacturing petroleum-free chemicals from lign

132 reases connectivity and is an important step towards maximal parallelism and the implementation of tw

133 With the push towards miniaturization of optical components, static me

134 red as an important prerequisite for efforts towards miniaturization.

135 nt years research efforts have been directed towards modeling the structure and dynamics of the under

136 rial quality and nano-fabrication procedures towards more coherent quantum circuits.

137 n of mesenchyme-free HIOs that can be primed towards more colonic or proximal intestinal lineages in

138 f infection-related complications as we move towards more personalized medicine.

139 hanges in breed distribution reflect a shift towards more productive environments.

140 nience samples and offer guidance for moving towards more representative and timely population estima

141 ure classification but have low contribution towards movement type and frequency classification.

142 ensing components outlines feasible pathways towards multifunctional and multimodal sensor platforms.

143 toms into phase-stable PICs marks a key step towards multiplexed quantum repeaters(7,8) and general-p

144 e progression and maintenance of AML, a bias towards mutated transcripts could have a significant imp

145 The BM composition was skewed towards myelopoiesis and transcriptome analysis of HSC/G

146 ator avoidance might also redirect dispersal towards nearby predator-free patches resulting in so-cal

147 To fully exploit this method, we must move towards new alloys and processes.

148 tly, we cover recent activity and challenges towards next-generation wearable non-invasive glucose mo

149 Partial river flow recovery (towards non-forested conditions) has been reported in de

150 s that bias the acquisition of immune memory towards non-self targets.

151 is very poor in HSAN III but can be improved towards normal by application of elastic kinesiology tap

152 ion and PARP1 shRNA knock-down returned PRPP towards normal, and (2) decreased intracellular phosphat

153 ms can adapt to existing pressures and shift towards ocean stewardship through incorporation of niche

154 Sensitivity of dsDNA structure towards OH radicals as the pro-oxidants has been utilize

155 a nutritional constraint can drive predators towards omnivory.

156 pportunity as we direct our research efforts towards one of the most pressing problems facing our pla

157 Excellent selectivity towards one- and two-base mismatches (1MM, 2MM) or scram

158 ment our knowledge and current understanding towards ongoing phylogenomic and evolutionary dynamics f

159 markers and might stimulate further research towards optimal diagnostic strategies.

160 rceived directionality of the movement (i.e. towards or away from the observer) was found to be criti

161 earning songs; however, song is not directed towards other individuals and has no obvious, immediate

162 (3D) carbon paper electrodes is one strategy towards overcoming this challenge, with partial relief a

163 However, their chemical instability towards oxygen, light and heat limits its applications i

164 commensals, cipR S. sonnei may be propelled towards pan-resistance by adherence to outdated internat

165 on biosensors and biosensing-related issues towards pandemic outbreaks.

166 ing infection, individual T cells are biased towards particular phenotypes.

167 ratification based on kidney biopsy findings towards personalized management based on clinical, morph

168 ergy can have another chance at contributing towards photogeneration in the cell.

169 Neuromorphic computing approaches aimed towards physical realizations of ANNs have been traditio

170 diagnosis and monitoring for prognostic use towards point-of-care testing.

171 diseases as a necessary and fundamental step towards precision medicine, which will benefit men's and

172 rm-function associations reflect convergence towards predictable trait combinations, indicating that

173 first and second positions, an initial step towards producing completely unnatural polypeptides in v

174 This work represents a step towards programmable photoswitchable regulation of a wid

175 is hybrid interface makes a substantial step towards quantum communication at large scale, as well as

176 presented system is a developmental platform towards radar-driven wearable continuous BGL monitors.

177 itors of PLV-LMCs during murine development, towards rational therapies that target their proliferati

178 A trend towards reduced primary failure should be further studie

179 PC786 showed a trend towards reduction of symptom score and mucous weight.

180 SON or FANCM confirms the bias of the former towards regions that replicate early and the skew of the

181 t replicate early and the skew of the latter towards regions that replicate late.

182 ehavioural response of 131 A. oculatus males towards relevant and controlled conspecific versus heter

183 ules stems from their antimicrobial activity towards relevant oral pathogens which has so far been ap

184 t, leaf and whole plant) and is a first-step towards representing mechanistically leaf ontogenetic pr

185 anifests in a profound switch in specificity towards S29 TopoIIalpha phosphorylation, a response nece

186 ttention, prediction, and learning processes towards salient information, at the timescale of online

187 many species can exhibit mounting behaviour towards same- or opposite-sex conspecifics(1), but it is

188 arbon-to-nitrogen ratio and shift metabolism towards scavenging nitrogen from purines relative to fre

189 y to design and engineer artificial pathways towards second generation meroterpenoids with valuable b

190 All programs were biased towards selecting start codons that were upstream of the

191 s increased chemical stability or propensity towards self-assembly.

192 and at all ages, there was a clear gradient towards shorter health expectancy with increasing number

193 position of regenerating communities shifted towards shorter statured, small-seeded and conservative

194 revailing winds can disrupt migratory routes towards slightly different goals, and thereby promote mi

195 communities in shortgrass prairie may shift towards slower growing, more stress-resistant species in

196 rmacologic and probiotic approaches directed towards specific TLR2 signaling processes might be devel

197 al in modern science, and requires an effort towards standardising data publication practices.

198 e to photodecomposition, and poorly reactive towards sterically bulky alkene substrates.

199 ision medicine approach, with research aimed towards stratifying patients into more homogeneous cohor

200 showed substantial scratch reduction mainly towards strong pruritogens.

201 Our work offers a new route towards studying phase-resolved spin dynamics and hybrid

202 Any transition towards sustainability can only be effective if far-reac

203 There is recently growing interest towards synthesized human milk oligosaccharides (HMOs) a

204 onducted instructed walk-and-reach movements towards targets flexibly positioned in the cage.

205 As the pH of ASL increases towards that of basolateral liquid, paracellular HCO(3)

206 ch as the SPCD, with more investment shifted towards the accurate and independent vetting of subject

207 test if EGFRvIII influences the sensitivity towards the alkylating agent temozolomide (TMZ).

208 ect proactive trials reflected starting bias towards the alternative action, which was overcome befor

209 eyond merely characterizing general patterns towards the associations among community assembly, compo

210 While searches were biased towards the beacons, we did not find any evidence that p

211 pine swift Tachymarptis melba, were captured towards the beginning and end of each breeding season to

212 o positions approximately 18 domains further towards the C terminus along titin.

213 cold ions in the inner wall surface implode towards the central axis.

214 s the boundary and spreads into the interior towards the central Labrador and Irminger basins after f

215 defence, with rates of aggression increasing towards the centre of home ranges.

216 er resistance and high transduction activity towards the co-enzyme NADH, delivering a wide linear ran

217 sistently overestimated out-group negativity towards the collective behaviour of their in-group.

218 B. hybridum allotetraploid, ND is stabilized towards the D-genome units, irrespective of the polyphyl

219 Future approaches towards the definition of refractory RA and the applicat

220 posed method can be used as a stepping stone towards the development of an accessible PD screening to

221 This review highlights recent progresses towards the development of NLC for brain targeting of bi

222 chanisms underlying COVID-19, paving the way towards the development of preventative and therapeutic

223 r Split-and-Mix Library on Beads-was applied towards the directed evolution of an anti-IgE Affibody (

224 These findings will help efforts towards the discovery of microbial-derived repellent/ovi

225 ion, while the ART group appeared to recover towards the diversity level of the healthy control.

226 of the species within its wintering grounds towards the east and north.

227 bacterial communities to flourish, typically towards the end of fermentation.

228 Southern Hemisphere tropospheric circulation towards the end of the twentieth century, including a po

229 ter the diversity of our membership and work towards the engagement of all members, from diverse back

230 ypothesis that biotic interactions intensify towards the equator.

231 Towards the foregoing aim, we review and synthesise evid

232 This work contributes towards the goal of cancer biomarker identification by e

233 y ecostates of infected individuals progress towards the healthy ecostate, coinciding with viral clea

234 Moving the RAP footward towards the heart decreased the cerebral tissue saturati

235 ozygous regions causes crossover remodelling towards the heterozygous regions in wild type Arabidopsi

236 ohydrate digestion and support the evidences towards the higher resistance of galactosyl-fructose lin

237 Drosophila model provide a powerful approach towards the identification and therapeutic exploitation

238 und IgE with a neuraminidase enzyme targeted towards the IgE receptor FcepsilonRI, and administering

239 affold possibly provides increased stability towards the intermediate Co(I) species.

240 s, or adapt the orientation of the filaments towards the membrane during membrane remodeling.

241 to four distinct subtypes; tumors that shift towards the mesenchymal phenotype upon recurrence are ge

242 the transport of many intracellular cargoes towards the minus end of microtubules (MTs).

243 for dynein-mediated intracellular transport towards the minus-ends of microtubules.

244 cale objects in 3D hydrogels provides a step towards the modular assembly of soft functional material

245 d diel coefficient as the surveys progressed towards the monsoon season suggest temporal shifts in GR

246 e rediscovery rates, guide experimental work towards the most promising metabolites, and identify enz

247 clude a decline in lymphopoiesis and skewing towards the myeloid lineage.

248 However, increasing evidence points towards the need for a tumor priming step to improve int

249 irthweight and gestational age may be biased towards the null.

250 gh coordinated vertical cell movement: cells towards the periphery of the placode move vertically upw

251 probiotic (Lactobacillus reuteri) treatment towards the reduction in periodontal inflammatory parame

252 ose a means of refocusing research questions towards the rich and complex components that comprise le

253 l to produce estimates of public perceptions towards the safety, importance, and effectiveness of vac

254 13)C over the transect from the control site towards the seep, suggesting that CO(2) exerts a strong

255 hlet extraction) were evaluated and compared towards the selective recovery of bioactive compounds.

256 This work paves a path towards the skyrmionic devices based on van der Waals la

257 8-1 complexes in multiple intermediate steps towards the SNARE complex.

258 on of novel substrates and enzyme activities towards the synthesis of monolignols.

259 Furthermore, metabolic reconfiguration towards the synthesis of protective metabolites of those

260 h on Arid5a, which has focused our attention towards the therapeutic potential of this factor in the

261 pects, pharmacokinetic behavior and efficacy towards the treatment of various neurological disorders

262 These in turn skew differentiation towards the tumor cell-of-origin and alter interactions

263 ascades are activated, many of them directed towards the tumor suppressor p53, which coordinates the

264 3D-SMART represents a critical step towards the untethering of single molecule spectroscopy.

265 s also suggest that overestimation increases towards the upper end of the risk spectrum.

266 r the integral valorization of this resource towards the zero-waste.

267 ificity of action of promoters and enhancers towards their targets in a tissue specific manner.

268 The efficiency of these materials towards these described applications is heavily influenc

269 IgE-mediated reactions towards these neoantigens are well studied; however, IgE

270 Towards this end, noncovalent functionalization offers a

271 Towards this end, positron emission tomography (PET) ima

272 Towards this end, we performed a protein-protein interac

273 Towards this goal we revisit the ideal free distribution

274 Towards this goal, the inactivation of members of the HI

275 rse array of fields are collectively working towards this goal.

276 elied on a variety of available data sources towards this objective, including electronic health reco

277 ularization method that improves convergence towards this optimal solution when data are noisy and th

278 Towards this, our current work seeks to develop the tech

279 le predominance and there was a predilection towards thoracic and lumbar vertebrae, with L4 being the

280 help to stratify treatments, guiding choice towards those which most effectively resolve the obstruc

281 usible, and increasing attention is directed towards thrombotic microembolism as the underlying cause

282 ponse to river damming: deltas transitioning towards tide dominance are currently gaining land, proba

283 jor scientific and technological innovations towards tight monitoring of diabetes.

284 tion was more frequent from San Diego county towards Tijuana than vice versa.

285 al sensor features of the Cu-SWCNT-Pc hybrid towards to physostigmine pesticide were performed.

286 MDK-modulated secretome educated macrophages towards tolerant phenotypes that promoted CD8(+) T cell

287 The new receptor displays selectivity towards two out of the seven PIPs, namely PI(3)P and PI(

288 ensor, a live-cell tubulin nanobody specific towards tyrosinated microtubules.

289 Progress towards UHC can be tracked using an index that captures

290 o all manifestations of GBS disease, studies towards understanding granadaene's toxic activity are hi

291 As a step towards understanding how neuronal maturation is regulat

292 id accumulation, our findings may contribute towards understanding processes that can ultimately infl

293 Work is just beginning towards understanding root mucilage and the proposed adh

294 ng crowd-sourcing, this initiative is a step towards understanding the limitations of existing state-

295 To provide potential clues towards understanding this high mortality, detailed clin

296 d birds exhibit a strong phylogenetic signal towards urban tolerance; however, they have largely been

297 The crucial next steps towards using single rare-earth ions for quantum network

298 A concurrent weather regime shift towards warmer, wetter conditions occurred throughout it

299 rtant role in the wide range of applications towards which polypeptides have been applied.

300 systems, that the interventions are targeted towards, will have already undergone repeated and widesp