ライフサイエンスコーパス: trachea

1 ze in IQGAP1 knockdown cells or in Iqgap1-/- trachea.

2 ed by more than only epithelial cells of the trachea.

3 humans, prevent tube dilation in Drosophila trachea.

4 s, gastrointestinal tract, cecal tonsil, and trachea.

5 f tissues expressing nectin-4, including the trachea.

6 extran, and microspheres in the skin and the trachea.

7 rom the same primordia that give rise to the trachea.

8 be expressed in the cells that will form the trachea.

9 s basal cell fate determination in the mouse trachea.

10 centration of AlPCS among the lung lobes and trachea.

11 in the mast cell-deficient (sash -/-) mouse trachea.

12 s of epithelial cells in exocrine glands and trachea.

13 for tracheomalacia in the upper and/or lower trachea.

14 e roles for Sox2 in the developing and adult trachea.

15 per trachea and 56.14% +/- 19.3 in the lower trachea.

16 Similar defects are observed for cilia in trachea.

17 iopaque tantalum disks, insufflated into the trachea.

18 rtilage rings along the entire length of the trachea.

19 ated the effects of obesity on the lungs and trachea.

20 ial tubes: the Drosophila salivary gland and trachea.

21 ere isolated from the lungs and the proximal trachea.

22 ane proteins, is expressed in the developing trachea.

23 rmed to remove mucus from within the ETT and trachea.

24 re important to bacterial clearance from the trachea.

25 ith highest levels of messages in testis and trachea.

26 ulted in a defect in colonization of the rat trachea.

27 Titf1) is expressed ventrally, in the future trachea.

28 mulated progressively within the ETT and the trachea.

29 ten obtained by placing a cuffed tube in the trachea.

30 ve natural killer (NK) cells in the infected trachea.

31 syrinx, is located at the caudal end of the trachea.

32 staff when sputum is present in a patient's trachea.

33 ain M41 bound to the epithelial cells of the trachea.

34 lication was most efficient in turbinate and trachea.

35 f cilia to calcium chloride on ex vivo mouse trachea.

36 tissues of the esophagus, phrenic nerves, or trachea.

37 he human-adapted H3 that bound mainly to the trachea.

38 ent of distinct T cell subpopulations in the trachea.

39 observed in ciliated epithelial cells of the trachea.

40 hondrogenic cells, is reduced in Cav3.2(-/-) tracheas.

41 ilure to advance the tube into the larynx or trachea (26/168 vs 0/158; p < 0.001) and/or impaired sig

42 expected mutant phenotypes in the developing trachea, a tubule network that has been studied as a mod

43 to be positioned with the orientation of the trachea above (40 degrees, trachea-up) or below (5 degre

44 ze morphogenesis of the embryonic Drosophila trachea (airway).

45 The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex multi

46 fection and replication by each virus in dog trachea, although EIV was more infectious in horse trach

47 % +/- 18.6 (standard deviation) in the upper trachea and 56.14% +/- 19.3 in the lower trachea.

48 ase in vector growth in the nasal cavity and trachea and a 50-fold decrease in the lungs.

49 clusively expressed in the epithelium of the trachea and airways.

50 (SA) and alpha2,6-linked SA residues in the trachea and alpha2,6-linked SA residues in the lung pare

51 iratory system, which consists of the lungs, trachea and associated vasculature, is essential for ter

52 efficiently in cells isolated from the lower trachea and at a higher temperature (37 degrees C) compa

53 lec-8 ligands were found on postmortem human trachea and bronchi and on upper airways in 2 compartmen

54 In the trachea and bronchi of the mouse, airway smooth muscle (

55 ies in both number and shape of cartilage in trachea and bronchi.

56 as detected in the epithelium throughout the trachea and bronchial airways and in bronchoalveolar lav

57 idin in the cilia of epithelial cells in the trachea and ependyma.

58 defective separation and malformation of the trachea and esophagus and results in the formation of a

59 iptional programs that specify the mammalian trachea and esophagus are unknown.

60 The trachea and esophagus arise from the separation of a com

61 racheoesophageal fistula (TEF), in which the trachea and esophagus fail to separate.

62 eptum formation and resolution into distinct trachea and esophagus requires endosome-mediated epithel

63 Osr1/Osr2) results in agenesis of the lungs, trachea and esophagus.

64 ssion of p63, a marker of basal cells in the trachea and esophagus.

65 , on sperm cells, and on cells that line the trachea and fallopian tubes in mammals.

66 ation of large foci of infected cells in the trachea and high levels of MV infection in the URT, part

67 The pseudostratified epithelium of the mouse trachea and human airways contains a population of basal

68 could be mimicked by treatment of both mouse trachea and human bronchi with specific SFK inhibitors.

69 nsistently, age-related SC loss in the mouse trachea and in muscle can be prevented by pharmacologic

70 ll surfaces of epithelial cells in the human trachea and in primary polarized AECs.

71 roteins to all tissues, binding of QX-RBD to trachea and kidney could not be blocked by preincubation

72 sults: 1) ACE2 is expressed similarly in the trachea and LAE, with lower expression in the SAE; 2) in

73 pe of constitutive CTMCs and induced MMCs in trachea and large airways in antigen-sensitized unchalle

74 that nearly abolished cough evoked from the trachea and larynx in anesthetized guinea pigs while hav

75 rior foregut, which gives rise to the future trachea and lung buds.

76 The esophagus, trachea and lung develop from the embryonic foregut, yet

77 oregut endoderm leads to absence of both the trachea and lung due to a failure in maintaining the res

78 e human gene is expressed in brain, thyroid, trachea and lung in addition to testis, we suggest that

79 ata and showed distinct signatures in ferret trachea and lung tissues specific to 1918 or 2009 human

80 alian respiratory system, consisting of both trachea and lung, initiates from the foregut endoderm.

81 expansion of Nkx2.1, an early marker for the trachea and lung, into adjacent endoderm including the s

82 phagus and stomach and the ventrally located trachea and lung.

83 yroid; and for respiratory function, such as trachea and lung.

84 o required for the normal development of the trachea and lung.

85 deposition of anthropogenic particles in the trachea and lungs of respiratory patients (here, +0.28 a

86 and short chain fatty acids (SCFAs) in both trachea and lungs.

87 es, but only sporadically (if at all) in the trachea and lungs.

88 were assessed for malacia that involved the trachea and main bronchi (reduction in cross-sectional a

89 Trachea and main bronchi did not show significant differ

90 Human trachea and main bronchi were dissected free of epitheli

91 We found that, in the trachea and main bronchi, loss of SM or cartilage result

92 x subjects (93%) had fluid in the subglottic trachea and main bronchi.

93 he formation of polyp-like structures in the trachea and main-stem bronchi.

94 drenal glands and spleen, as well as atretic trachea and palate defects were observed in the homozygo

95 especially in the luminal epithelium of the trachea and pessulus.

96 al markers SOX2 and P63 into the prospective trachea and primary bronchi.

97 lial networks, with specific emphasis on the trachea and salivary gland of Drosophila melanogaster an

98 'unrolling' the apical surface of wild-type trachea and the hindgut reveals previously unrecognized

99 The mammalian respiratory system--the trachea and the lungs--arises from the anterior foregut

100 sted replicated efficiently in explants from tracheas and bronchi, with limited replication in alveol

101 city-evoked ATP release from freshly excised tracheas and dye uptake in primary tracheal epithelial c

102 sympathetic neurons were isolated from human tracheas and grown in serum-free medium for one week.

103 to the reduction of B. bronchiseptica in the tracheas and lungs.

104 howed that many human viruses can infect dog tracheas and that reassortment with CIV results in viabl

105 res were taken from the nares, oropharynx or trachea, and any open wound routinely on admission to th

106 significant mutagenic response in the lung, trachea, and bladder of exposed animals, as reflected by

107 entities of fibroblasts in the heart, lungs, trachea, and bladder.

108 ofile, long duration of action on guinea pig trachea, and longer than salmeterol duration of action i

109 igin H10N7 IAV replicated well in turbinate, trachea, and lung, but replication was most efficient in

110 ricted responses in tissues such as the gut, trachea, and malpighian tubules.

111 phs of selected histologic lung, lymph node, trachea, and nasal turbinate tissue sections.

112 (dVHL) in the epithelial tubule network, the trachea, and show that dVHL regulates branch migration a

113 ge and smooth muscle structures in mammalian trachea are derived from tracheal mesoderm, and tracheal

114 The esophagus and trachea arise from the dorsal and ventral aspects of the

115 like the hemolymph channel and the acoustic trachea as well as the extension of the tectorial membra

116 d that reducing Mmp2 activity perturbed disc-trachea association, altered peritracheal distributions

117 esence of hMCA protein in brain, thyroid and trachea at the identical mass, 44 kDa, as in human testi

118 d from the respiratory trachea, the acoustic trachea (AT), which transfers sound from the mesothoraci

119 us Slurper, combined with orientation of the trachea below horizontal, prevents accumulation of secre

120 ed in subsets of epithelial cells lining the trachea, bronchi, and tracheal glands.

121 the respiratory tract of ferrets, including trachea, bronchus, and lung alveolus tissues.

122 s ago; of these, 1.5 million (19%) were from trachea, bronchus, and lung cancer.

123 itial colonization of the mouse nose and the trachea but not of the lungs.

124 tion protein expressed preferentially in the trachea, but how it gets there is not understood.

125 is in cells including the developing CNS and trachea, but little is known about its post-blastoderm f

126 ccurs in the upper respiratory tract and the trachea, but little is known about the initial events of

127 er infectious titres in nasal washes and the trachea, but not in the lungs, supporting clinical evide

128 Specifically, distal presence of rigid trachea can limit out-of-plane motion in the longitudina

129 1 or Spry2 in basal cells of the adult mouse trachea caused an increase in steady-state proliferation

130 The cuff-trachea contact area and the percentage of tracheal wall

131 d tracheal wall pressure throughout the cuff-trachea contact area was determined using an internal pr

132 el beta1 subunit enhances cholinergic-evoked trachea contractions.

133 ith expression on mucosal epithelia from the trachea, cornea, and conjunctiva--tissues believed to be

134 cross-sectional area of the upper and lower trachea correlated well with decreases in sagittal (r =

135 t, ablation of Hoxa5 in mesenchyme perturbed trachea development, lung epithelial cell differentiatio

136 aling between endoderm and mesoderm promotes trachea development.

137 er, only in the main bronchi, but not in the trachea, did the loss of SM or cartilage lead to a circu

138 addition to SM defects, cartilage-deficient tracheas displayed epithelial phenotypes, including decr

139 No pneumonia was found in trachea-down sheep (p = .007).

140 In trachea-down sheep, all mucus moved toward the glottis a

141 40 degrees, trachea-up) or below (5 degrees, trachea-down) horizontal.

142 BMP pathway components in vivo in the mouse trachea during epithelial regeneration from basal cells

143 on glass surfaces, colonized mouse lung and trachea efficiently, but had a decreased association wit

144 3 cells, or in primary differentiated murine trachea epithelial cell cultures, indicating there was n

145 describe a novel method for culturing murine trachea epithelial cells on a native basement membrane a

146 th defect esophageal atresia with or without trachea-esophageal fistula (EA/TEF).

147 Abnormal trachea-esophageal separation leads to the common birth

148 t the transcription factor Isl1 orchestrates trachea-esophageal separation through modulating a speci

149 ene has been found in patients with abnormal trachea-esophageal separation.

150 lateral sympathetic nerve denervation of the trachea essentially abolished these reflexes (10+/-9% an

151 ove extracellular [K(+)]: 22 +/- 1 mm in pig trachea ex vivo and 16 +/- 1 mm in mouse trachea in vivo

152 ed with wild-type tracheas, the Tmem16a(-/-) tracheas exhibited a >60% reduction in purinoceptor (UTP

153 normal airway hydration because Tmem16a(-/-) tracheas exhibited significant, neonatal, lumenal mucus

154 ntation of hands, larynx, vascularized knee, trachea, face, and abdominal wall has been performed.

155 Proinflammatory lipid precursors in the trachea following 1918 infection correlated with severe

156 facilitating their movement into the beetle trachea for transport to the next pine tree.

157 uppress ectopic lung budding but does rescue trachea formation and NKX2-1 expression.

158 ies suggest its essential role in Drosophila trachea formation and Xenopus gastrulation.

159 , keeping the lumen of the ETT, and proximal trachea, free from secretions.

160 ucose flux were also observed across excised trachea from LPS-treated mice.

161 ion/temporal-force responses were similar in trachea from MYPT1(SM+/+) , MYPT1(SM-/-) and the knock-i

162 Furthermore, tracheas from Bpifa1(-/-) mice are hypercontractile, and

163 Tracheas from CBA donors were heterotopically transplant

164 Like those from the mouse trachea, human airway basal cells both self-renew and ge

165 For the larynx-with-trachea images, the magnitude of the artifacts depended

166 nd remodeling is known to occur in the mouse trachea in sustained inflammation, but whether intrapulm

167 LTC(4) or LTD(4) in constricting guinea pig trachea in vitro and comparable activity in eliciting a

168 imilarly, addition of hypotonic PBS to mouse trachea in vivo decreased AQP5 within 1 h, an effect blo

169 pig trachea ex vivo and 16 +/- 1 mm in mouse trachea in vivo.

170 assessed by electrical field stimulation of tracheas in the presence/absence of gallamine.

171 on was eventually observed in the membranous trachea, indicating a reestablishment of graft perfusion

172 We orthotopically transplanted C57Bl/6 (H-2) tracheas into CBA.J (H-2) recipients who afterwards rece

173 anterior foregut tube into the esophagus and trachea involves cell proliferation and differentiation,

174 The Drosophila trachea is a branched tubular epithelia that transports

175 f neural stem cells (neuroblasts), glia, and trachea is coordinated and whether coordinated growth am

176 is that antigen-induced contraction of mouse trachea is epithelium-independent, and requires mast cel

177 tment of neutrophils into influenza-infected trachea is essential for CD8(+) T cell-mediated immune p

178 When the trachea is oriented above horizontal, a flow of mucus fr

179 The origin of the trachea is suggested to result either from respiratory o

180 Their upper vocal tract, including the trachea, is shorter than predicted for their body size.

181 sed the mechanism by which antigen contracts trachea isolated from actively sensitized mice.

182 istamine release or contractile responses in trachea isolated from sensitized mast cell-deficient (sa

183 thelia sampled by fiberoptic bronchoscopy of trachea, large airway epithelia (LAE), and small airway

184 s, the T-cell-dependent induction of MMCs in trachea, large bronchi, and small intestine provides num

185 l epithelium, histopathologic changes in the trachea, large intestine, and pancreas, and abnormalitie

186 other grafts such as those of uterus, penis, trachea, larynx, or abdominal wall have confirmed the po

187 oward the lungs on the dependent part of the trachea, leading to an "intratracheal route" of coloniza

188 , appropriate dorsoventral patterning of the trachea leads to the formation of periodic cartilage rin

189 Deformation of the trachea, likely the cause of the mutation's lethality, w

190 heal inoculation, it was recovered also from trachea, lung, and cerebrum.

191 these mutants show that the loss or gain of trachea/lung progenitor identity is accompanied by an ex

192 Consequently, the trachea, lungs, and cardiopulmonary vasculature have bee

193 l antigens were detected in nasal turbinate, trachea, lungs, and intestine with acute bronchiolitis p

194 accompanied by luminal size reduction in the trachea, mainstem bronchi, and proximal airways.

195 n vivo lymphangiogenesis in animals in mouse trachea, Matrigel plug, and cornea pocket assays.

196 Amyloids applied into the trachea may either be disseminated through the circulati

197 signaling in mesoderm is critical to confer trachea mesenchymal identity in human and mouse.

198 in a rigid tracheal model and a benchtop pig trachea model (before and after a standardized cuff move

199 ucus, mostly on the nondependent part of the trachea, moved toward the glottis at an average velocity

200 From the proximal trachea, mucus eventually moved toward the lungs on the

201 ight bronchus (n = 4; 20%), and the cervical trachea (n = 3; 15%).

202 , the carina (n = 10; 50%), the supracarinal trachea (n = 9; 45%), the right bronchus (n = 4; 20%), a

203 ies, anal atresia, cardiovascular anomalies, trachea-oesophageal fistula, renal anomalies, limb defec

204 struction of several complex tissues such as trachea, oesophagus, and skeletal muscle in animal model

205 nital absence of complex tissues such as the trachea, oesophagus, or skeletal muscle have few therape

206 T/CT images of the lungs and the larynx with trachea of a deceased swine were obtained after injectin

207 The longer trachea of birds compared to other tetrapods made them l

208 Further, in the trachea of both treated and untreated monkeys the mRNA l

209 ion of canine, equine, and human IAVs in the trachea of the dog, a species to which humans are heavil

210 vo situations such as the development of the trachea of the Drosophila embryo.

211 xpression increased more than sixfold in the trachea of wild-type and Cxcr2(-/-) mice, but intratrach

212 pon these experiments, RNA was isolated from tracheas of 20 chickens infected with M. gallisepticum R

213 demonstrate substantial angiogenesis in the tracheas of ADA-deficient mice in association with adeno

214 Interestingly, the tracheas of both the Tmem16a(-/-) and the CFTR(-/-) mice

215 ced recovery and attenuated virulence in the tracheas of experimentally infected chickens.

216 is activated in the respiratory system, the trachea, of Drosophila.

217 tly less objective noise at the level of the trachea on mediastinal and lung parenchymal images (P <

218 Associated deformity of the trachea or great vessels was recorded as absent or prese

219 nasal mucosa, with no virus detected in the trachea or lungs.

220 espiratory tract of ferrets rather than from trachea or the lower airways.

221 olol (2 microm, administered directly to the trachea) or bilateral sympathetic nerve denervation of t

222 airway obstruction in sheep with the ETT and trachea oriented below horizontal.

223 gnificantly reduced viral replication in the trachea (p < 0.029).

224 in the legs; the cross-sectional area of the trachea penetrating the leg orifice scaled with mass1.02

225 on of Bmp4 (Bmp4(cko)) resulted in a loss-of-trachea phenotype that closely resembles the Floyd type

226 The lesion within the trachea produced 2 artifacts, symmetrically aligned with

227 The microvasculature of the mouse trachea provides an ideal opportunity to study this proc

228 and exciting insights into how the lungs and trachea regenerate in response to injury and have allowe

229 child using a decellularized deceased donor trachea repopulated with the recipient's respiratory epi

230 ition to microscopic examination of lung and trachea sections, show that mucosal infection of guinea

231 For the trachea, several initial clinical studies have been repo

232 dendritic cells (IDCs) are recruited to the trachea shortly after influenza infection through type I

233 fferentially expressed in the E11.5 lung and trachea showed that melanoma inhibitory activity (Mia1)

234 Confocal images of nonsensitized tracheas showed slight fluorescence for P2Y6 receptors i

235 act via the ciliated epithelial layer of the trachea, some strains can also replicate in the kidneys,

236 n of wild type pgant35A under control of the trachea-specific breathless (btl) promoter results in pa

237 During larval stages the cerebral trachea splits into several main (primary) branches that

238 Infusing thrombin or trypsin via the trachea strongly activated vagal lung C-fibres with acti

239 -CFTR interaction was investigated using pig trachea submucosal gland secretion model.

240 ions was isolated from both the lung and the trachea, suggesting that it has a broader organ tropism

241 About 60% of the mutants have a short trachea, suggesting that the primary budding site of the

242 derived from bronchial cell lines and murine tracheas, supporting a role for EC in early airway clear

243 a, although EIV was more infectious in horse trachea than CIV.

244 s secondary to an expansion of the embryonic trachea that might result from improper stratification o

245 air-filled tube derived from the respiratory trachea, the acoustic trachea (AT), which transfers soun

246 arding the respiratory system, including the trachea, the lung proper, and the diaphragm, has lagged

247 ult tissues such as ectodermal placodes, the trachea, the ureter, the gut and the neuroepithelium.

248 When compared with wild-type tracheas, the Tmem16a(-/-) tracheas exhibited a >60% red

249 ribution to lungs, stomach-intestine, liver, trachea-throat and blood at the end of the imaging perio

250 use mucous metaplasia in Stat6-null cultured trachea, thus identifying a novel pathway that stimulate

251 natural anatomical orientation of the rigid trachea, thyroid and the pulsating carotid artery, we hy

252 ycosylation variants lost binding to chicken trachea tissue and an ELISA-presented alpha2,3-linked si

253 odified electrode and the surface of excised trachea tissue at 37 degrees C indicate steady-state res

254 Trachea tissue excised from a mouse model of cystic fibr

255 cholesterol at the surface of excised mouse trachea tissue is reported.

256 Formalin-fixed lung or trachea tissue specimens from four infants and one adole

257 han the response observed at wild-type mouse trachea tissue.

258 rospheres were instilled into the subglottic trachea to assess pulmonary aspiration.

259 is a medical device placed in the patient's trachea to assist breathing and delivering oxygen into t

260 of the steady-state and naphthalene-injured trachea to evaluate the predictions of this model.

261 t the base of the airway at the split of the trachea to the lungs.

262 glands in tissues including skin, esophagus, trachea, tongue, eye, bladder, testis and uterus.

263 ent tissue regions, such as ear skin and the trachea, tongue, peritoneum, lungs, and bone marrow.

264 orizontal, a flow of mucus from the proximal trachea toward the lungs is highly associated with bacte

265 The heterotopic rat trachea transplant model was used.

266 Orthotopic trachea transplantations were performed between Lewis do

267 eria into the lumen of intact isolated swine tracheas triggers CFTR-dependent ASL secretion by the su

268 We found that in the trachea, unlike in skin and intestine, CTMCs and MMCs bo

269 Pneumonia was found in 6/8 of trachea-up sheep and the same microorganisms were isolat

270 In all trachea-up sheep, abnormal tracheal mucus clearance was

271 rientation of the trachea above (40 degrees, trachea-up) or below (5 degrees, trachea-down) horizonta

272 from 1-day-old piglets in situ in explanted tracheas, using optical methods to monitor mucus secreti

273 l mesoderm (CVM), the visceral branch of the trachea (VBs) and the secretory portion of the salivary

274 endently derived primary human cultures from trachea versus bronchioles.

275 tory response in cells representative of the trachea versus small airway bronchiolar cells.

276 d either in sagittal (P=0.02) or in 3-vessel trachea view (P<0.001) were lower in fetuses with CoA.

277 s muscle that spans the dorsal aspect of the trachea was abnormal in Tmem16a mutants.

278 The proximal trachea was colonized in all sheep.

279 bacterial colonization in the mouse nose and trachea was detected.

280 -positive scans, cross-sectional area of the trachea was measured manually at 3 predetermined levels

281 In 2010, a tissue-engineered trachea was transplanted into a 10-year-old child using

282 Using electron tomography on mouse trachea, we show that basal bodies are collectively hook

283 Trachea were isolated from mice (C57BL/6J) that had been

284 ea and sagittal and coronal diameters of the trachea were measured 1 cm above the aortic arch and 1 c

285 end-expiratory cross-sectional areas of the trachea were measured.

286 L) and ATP-stimulated mucin secretion in the trachea were reduced compared to WT-matched littermates.

287 to RSV-infected primary human cultures from trachea were regulated by epithelial-specific ets homolo

288 Smooth-muscle cells from mouse tracheas were assayed in vitro for signaling pathways.

289 For the trachea, where finely tuned neuromuscular activity is no

290 in-1 and epiphycan were specific for rib and trachea, whereas asporin was particularly abundant in th

291 racking and epithelial attenuation in cattle trachea, which could facilitate coinfection with other p

292 forming dynamic imaging studies in the mouse trachea, which is a commonly used in vivo model of human

293 anced lung pathology and EBOV antigen in the trachea, which supports increased virus transmission fro

294 tes showed an impaired ability to infect dog tracheas, while EIVs that circulated near the time of CI

295 vealed 1.5 kb hMCA transcripts in testis and trachea with lower levels in thyroid and spinal cord.

296 Inoculating dog tracheas with various human IAVs (hIAVs) showed that the

297 tant esophagus morphologically resembles the trachea, with ectopic expression of Nkx2.1, a columnar,

298 for how gene expression is controlled in the trachea, with trh regulating expression of vvl and kni,

299 bility of a decellularized tissue-engineered trachea within a child.

300 f secretions within the lumen of the ETT and trachea, without need for conventional tracheal suctioni