ライフサイエンスコーパス: tracheal

1 were examined microscopically to define the tracheal abnormalities present in CTRD.

2 e gain in the AT by numerically modeling the tracheal acoustic behavior using the finite-element meth

3 aginal disc that produces Hh and is near the tracheal air sac primordium (ASP) and myoblasts.

4 ls (hemocytes) at the respiratory epithelia (tracheal air sacs) of the thorax and head.

5 on the microvascular integrity of orthotopic tracheal allografts as an anatomic basis for the develop

6 e produced transgenic mice carrying a bovine tracheal AMP gene promoter-controlled PG-1 transgene.

7 Both systemic (tracheal and bronchial) and pulmonary circulations perfu

8 xperiments show that MECs contribute to both tracheal and esophageal epithelium, and Isl1 is required

9 terrogate the expression of newly-identified tracheal and esophageal markers in Sox2/Nkx2-1 compound

10 ation, and discover that the majority of the tracheal and esophageal transcriptome is NKX2-1 independ

11 robial mixture reduced the virus load in the tracheal and lung tissue and significantly reduced the c

12 trated that sphingosine is present in nasal, tracheal, and bronchial epithelial cells and constitutes

13 l branching, it is integral for building the tracheal architecture and promoting airway growth.

14 In human preterm infants, tracheal aspirate Clec9a expression positively correlate

15 Tracheal aspirate fluid and cells were collected within

16 hil transepithelial migration into cell-free tracheal aspirate fluid from patients to recapitulate th

17 ncentration of NETs was augmented in plasma, tracheal aspirate, and lung autopsies tissues from COVID

18 Tracheal aspirates from human infants with and without R

19 Tracheal aspirates from premature human infants were col

20 ice, Escherichia coli lipopolysaccharide, or tracheal aspirates from preterm infants exposed to chori

21 Human tracheal aspirates from RSV-infected infants showed elev

22 specimens (bronchoalveolar lavage specimens, tracheal aspirates, and sputum samples) in addition to s

23 one showing laryngeal atresia and the other, tracheal atresia.

24 Ramification inside IFMs proceeds until tracheal branches fill the myotube.

25 4 coordinates growth of synaptic boutons and tracheal branches to modulate larval hypoxia responses.

26 modulate the growth of synaptic boutons and tracheal branches, respectively.

27 genIV levels, while Laminin is present along tracheal branches.

28 miR-274 expression in glia or by increasing tracheal branches.

29 modulates the growth of synaptic boutons and tracheal branches.

30 of models, including border cell migration, tracheal branching, blood vessel sprouting, and the migr

31 ween 1980 and 2014, including 5656423 due to tracheal, bronchus, and lung cancer; 2484476 due to colo

32 gallbladder and biliary; pancreatic; larynx; tracheal, bronchus, and lung; malignant skin melanoma; n

33 e" substances are most probably initiated by tracheal brush cells (BC).

34 y shaped lung cysts located mainly below the tracheal carina.

35 causes loss of Tbx4(+) tracheal mesoderm and tracheal cartilage agenesis.

36 In contrast, tracheal cartilage, vasculature, and neural innervation

37 We further show that tracheal cells are competent to undergo apoptosis, even

38 ix metalloproteinase 1 (MMP1) is required in tracheal cells for normal invasion speed and for the dyn

39 normal bronchial epithelial (NHBE) cells and tracheal cells from patients with cystic fibrosis (CFT1-

40 However, individual tracheal cells occupy largely separate territories, poss

41 that miR-274 can function in the neurons or tracheal cells to modulate the growth of synaptic bouton

42 uding in synaptic boutons, muscle cells, and tracheal cells.

43 ntally-regulated DrICE function rarely kills tracheal cells.

44 iary rootlets of multiciliated ependymal and tracheal cells.

45 5.8%] vs 2.5% [IQR: 0%-6.7%], P < .001), and tracheal collapse (201 mm(2) [IQR: 181-239 mm(2)] vs 229

46 weight reduction, which correlated with less tracheal collapse and air trapping at end-expiration che

47 is challenge, we identified a new biomarker (tracheal colonization factor A, TcfA) for detection of B

48 Purpose To evaluate lung parenchymal and tracheal CT morphology before and 6 months after bariatr

49 Tracheal cytotoxin (TCT), a monomer of DAP-type peptidog

50 Bacteriome isoforms specifically cleave the tracheal cytotoxin (TCT), a peptidoglycan monomer releas

51 B. pertussis virulence factor tracheal cytotoxin (TCT), a secreted peptidoglycan break

52 Thus, tracheal-derived MMP1 sustains branch invasion by modula

53 ted deletion of murine homologs important to tracheal development in mice.Measurements and Main Resul

54 We conclude that Yorkie has a dual role in tracheal development to ensure proper tracheal growth an

55 At the initiation of tracheal development, endoderm begins to express Nkx2.1,

56 s (vvl), and cut (ct), key genes involved in tracheal development, this study provides important insi

57 the importance of Wnt/Fgf crosstalk in early tracheal development.

58 novo mutations in genes required for normal tracheal development.Methods: CTRD and normal tracheal t

59 a(2+) transients are closely associated with tracheal elements, which dynamically extend filopodia th

60 tion of Hif-2alpha but not Hif-1alpha caused tracheal endothelial cell apoptosis, diminished pericyte

61 gnificant increase in neutrophil tracking in tracheal epithelia of the treatment calves compared to c

62 th satellite proteins in human multiciliated tracheal epithelia, and its loss inhibits motile cilioge

63 inked receptor to be able to attach to human tracheal epithelial and alveolar cells.

64 ults were recapitulated in Gas2l2(-/-) mouse tracheal epithelial cell (mTEC) cultures and in X. laevi

65 rway murine nasal epithelial cell and murine tracheal epithelial cell cultures and attenuated virus r

66 We employed a highly optimised ovine tracheal epithelial cell model to assess the colonisatio

67 Human tracheal epithelial cells (HTEpC) were cultured with IL-

68 zed swine nasal epithelial cells (siNEC) and tracheal epithelial cells (siTEC) that retained the abil

69 pregulation of cytokines and chemokines from tracheal epithelial cells (TECs) in vitro and tracheal t

70 Mouse tracheal epithelial cells grown at an air-liquid interfa

71 l lymphopoietin (TSLP) and GM-CSF in primary tracheal epithelial cells isolated from C57BL/6NJ mice.

72 Indeed, exposure of mouse tracheal epithelial cells to IL-1beta or IL-1alpha resul

73 Addition of exogenous TNF-alpha to mouse tracheal epithelial cells was sufficient to attenuate SP

74 of allergic asthma, as well as primary mouse tracheal epithelial cells, to evaluate the relevance of

75 thymic stromal lymphopoietin and GM-CSF from tracheal epithelial cells.

76 r time, we lesioned small areas of the mouse tracheal epithelium (1 to 12 cells) using a femtosecond

77 tein Gpr177 (also known as Wntless) in mouse tracheal epithelium causes a significant reduction in th

78 h single cell RNA-sequencing analysis of the tracheal epithelium from smokers and non-smokers, we gen

79 intestinal epithelium of the fly and in the tracheal epithelium of mice exhibit transient activation

80 the presumptive Sox2+ esophageal and Nkx2-1+ tracheal epithelium.

81 d with disease are present in both nasal and tracheal epithelium.

82 e, with virus located in the pneumocytes and tracheal epithelium.

83 ogenitors differentiate toward esophageal or tracheal epithelium.

84 for the establishment and maintenance of the tracheal epithelium.

85 (LAIV), which was attenuated in mice and dog tracheal, explants compared to CIV H3N8 wild type.

86 Loss of TrpML leads to increased tracheal filopodial numbers, growth, and increased CNS R

87 set of these microdomain transients promotes tracheal filopodial retraction and in turn modulate CNS

88 temporally correlated with the initiation of tracheal filopodial retraction.

89 emonstrated similar sensitivities for bovine tracheal force development and phosphorylation of RLC, M

90 l results obtained, it is discerned that the tracheal geometry is the main factor contributing to the

91 ole in tracheal development to ensure proper tracheal growth and functionality.

92 N8 (A/duck/Ukraine/1963), with assessment of tracheal histopathology, pathogen load, and transcriptom

93 elation of anterior junction line length and tracheal index with residual volume/total lung capacity

94 Once-daily, intra-tracheal injections of HO-exposed mice with ML335 or BL1

95 ary bacterial infection after a single intra-tracheal instillation at a very low dosage of 0.1 mg/kg.

96 entilation failure group, higher FIO2 before tracheal intubation (>= 70%) was associated with severe

97 ied secondary outcomes included the need for tracheal intubation (among patients not intubated at bas

98 ittle is known about the association between tracheal intubation and survival in this setting.

99 ngoscopy attempts in children with difficult tracheal intubation are associated with a high failure r

100 witching the device following a failed first tracheal intubation attempt was more successful than a s

101 After a failed first tracheal intubation attempt, immediate switching of the

102 n, and establish the effect of more than two tracheal intubation attempts on complications.

103 ional algorithm, comprising a maximum of two tracheal intubation attempts with each device, followed

104 Tracheal intubation can be avoided by the start of the N

105 registry consists of prospectively collected tracheal intubation data from 13 children's hospitals in

106 To determine whether tracheal intubation during adult in-hospital cardiac arr

107 ic patients with in-hospital cardiac arrest, tracheal intubation during cardiac arrest compared with

108 Tracheal intubation during cardiac arrest.

109 and January, 2015, 1018 difficult paediatric tracheal intubation encounters were done.

110 The study included 956 tracheal intubation encounters; 424 tracheal intubations

111 Patients were randomly assigned to undergo tracheal intubation facilitated by rocuronium (n = 624)

112 Tracheal intubation failed in 19 (2%) of cases.

113 ttic, then surgical airway access in case of tracheal intubation failure.

114 ication, these findings do not support early tracheal intubation for adult in-hospital cardiac arrest

115 do not support the current emphasis on early tracheal intubation for pediatric in-hospital cardiac ar

116 Primary tracheal intubation group included children without expo

117 invasive ventilation is widely used to avoid tracheal intubation in critically ill children.

118 All patients undergoing tracheal intubation in participating sites were included

119 Tracheal intubation in prehospital emergency care is cha

120 No restrictions were given for tracheal intubation indication.

121 namic instability and oxygenation failure as tracheal intubation indications were associated with car

122 Tracheal intubation is common during adult in-hospital c

123 Importance: Tracheal intubation is common during pediatric in-hospit

124 Tracheal intubation is common in the care of critically

125 Tracheal intubation is commonly performed in critically

126 e and training level), and practice factors (tracheal intubation method and use of neuromuscular bloc

127 well suited for use in prehospital emergency tracheal intubation of adult patients.

128 xemia is the most common complication during tracheal intubation of critically ill adults and may inc

129 incidence of cardiovascular collapse during tracheal intubation of critically ill adults compared wi

130 ag-mask device (bag-mask ventilation) during tracheal intubation of critically ill adults prevents hy

131 ressions more than 1 minute occurring during tracheal intubation or within 20 minutes after tracheal

132 ed patient, clinician, and practice data and tracheal intubation outcomes.

133 Tracheal intubation quality improvement data were prospe

134 The most frequently attempted first tracheal intubation techniques were direct laryngoscopy

135 tion, establish the success rates of various tracheal intubation techniques, catalogue the complicati

136 ically significant difference with regard to tracheal intubation times, number of attempts or difficu

137 ates, we randomly assigned adults undergoing tracheal intubation to receive either ventilation with a

138 y on chest radiography in the 48 hours after tracheal intubation was 16.4% and 14.8%, respectively (P

139 ritically ill adults (>=18 years) undergoing tracheal intubation were randomly assigned (1:1, block s

140 5% (n = 1,501) of 15,810 patients undergoing tracheal intubation with bag-mask ventilation during the

141 th in-hospital cardiac arrest, initiation of tracheal intubation within any given minute during the f

142 nt factors (demographics and indications for tracheal intubation), provider factors (discipline and t

143 the complications of children with difficult tracheal intubation, and establish the effect of more th

144 To determine whether ketamine use for tracheal intubation, compared to other sedative use, is

145 ) to characterise risk factors for difficult tracheal intubation, establish the success rates of vari

146 Among critically ill adults undergoing tracheal intubation, patients receiving bag-mask ventila

147 primary respiratory diagnosis/indication for tracheal intubation, presence of difficult airway featur

148 es were the number of attempts to successful tracheal intubation, time to glottis passage and first e

149 Tracheal intubation-associated cardiac arrest was define

150 Tracheal intubation-associated cardiac arrest was report

151 Tracheal intubation-associated cardiac arrests occurred

152 Tracheal intubation-associated cardiac arrests were much

153 ation failure was not associated with severe tracheal intubation-associated events (5% vs 5% without

154 Severe tracheal intubation-associated events (cardiac arrest, e

155 outcome is the occurrence of either specific tracheal intubation-associated events (hemodynamic trach

156 was not independently associated with severe tracheal intubation-associated events (p = 0.35) or seve

157 tion as well as its association with adverse tracheal intubation-associated events and oxygen desatur

158 ntilation failure was associated with severe tracheal intubation-associated events and severe oxygen

159 Specific tracheal intubation-associated events or oxygen desatura

160 was not independently associated with severe tracheal intubation-associated events or severe oxygen d

161 al intubation-associated events (hemodynamic tracheal intubation-associated events, emesis with/witho

162 tubation (>= 70%) was associated with severe tracheal intubation-associated events.

163 oninvasive ventilation within 6 hours before tracheal intubation.

164 1248 adult patients needing out-of-hospital tracheal intubation.

165 terval between induction and 2 minutes after tracheal intubation.

166 on; or cardiac arrest or death within 1 h of tracheal intubation.

167 out complications in children with difficult tracheal intubation.

168 acheal intubation or within 20 minutes after tracheal intubation.

169 oximately one in 10 PICU patients undergoing tracheal intubation.

170 invasive ventilation in the 6 hours prior to tracheal intubation.

171 events and severe oxygen desaturation during tracheal intubation.

172 formation and prevent VAP occurrence during tracheal intubation.

173 vere oxygen desaturation compared to primary tracheal intubation.

174 e Primary outcome was the rate of successful tracheal intubation; equivalence range was +/- 6.5% of s

175 g-mask ventilation is commonly used prior to tracheal intubation; however, the epidemiology, risk fac

176 or receipt between induction and 2 min after tracheal intubation; or cardiac arrest or death within 1

177 uded 956 tracheal intubation encounters; 424 tracheal intubations (44%) occurred after noninvasive ve

178 were prospectively collected for all initial tracheal intubations in 25 PICUs from July 2010 to March

179 A total of 5,232 pediatric tracheal intubations were evaluated.

180 d cardiac arrests were much more common with tracheal intubations when the child had acute hemodynami

181 atures, more experienced provider level, and tracheal intubations without use of neuromuscular blocka

182 cardiac arrests occurred during 1.7% of PICU tracheal intubations.

183 s, but only the wild-type virus was found in tracheal lavage fluids and urine.

184 tissue or muscle, large defects >50% of the tracheal length still present a clinical challenge.

185 AIV H3N8 exhibited significantly more severe tracheal lesions and mucosal thickening than chickens in

186 lowing 1918 infection correlated with severe tracheal lesions.

187 ability, and alveolar hemorrhage after intra-tracheal lipopolysaccharide (LPS).

188 lls, was the major source of TF during intra-tracheal LPS-induced ALI.

189 he total volume and the relationship between tracheal lumen diameter, length and volume are also pres

190 se model by Alzet pump significantly reduced tracheal lumen obliteration (p < 0.05), decreasing apopt

191 nd avidity indices of IgG in sera and IgA in tracheal, lung, and intestinal secretions, significantly

192 chea are derived from tracheal mesoderm, and tracheal malformations result in serious respiratory def

193 y other major tissues, namely, epidermis and tracheal matrix.IMPORTANCE Ascoviruses are large DNA vir

194 learning [9] and is thought to phonate with tracheal membranes [10, 11] instead of the two independe

195 Instead of the main sound source, the tracheal membranes constitute a morphological specializa

196 Birds with experimentally disabled tracheal membranes were still able to phonate.

197 two oscine-like labial pairs and the unique tracheal membranes, which collectively represent the lar

198 fetal mouse mesoderm causes loss of Tbx4(+) tracheal mesoderm and tracheal cartilage agenesis.

199 rived lateral plate mesoderm (LPM) generates tracheal mesoderm containing chondrocytes and smooth mus

200 ctures in mammalian trachea are derived from tracheal mesoderm, and tracheal malformations result in

201 s required along with WNT to generate proper tracheal mesoderm.

202 The tracheal microvasculature of mice, with conditionally de

203 udied inward short-circuit currents (Isc) in tracheal mucosa from human, sheep, pig, ferret, and rabb

204 By providing stabilized access to the tracheal mucosa without intubation, our setup uniquely a

205 infiltration of inflammatory cells into the tracheal mucosa.

206 f transcriptomic perturbations in avian host tracheal mucosae infected with virulent, immunopathologi

207 In ovine models of mucus clearance (tracheal mucus velocity and mucociliary clearance), inha

208 -cig liquid containing nicotine also reduced tracheal mucus velocity in a dose-dependent manner and e

209 tase for 3 days, which resulted in prolonged tracheal mucus velocity reduction, mucus hyperconcentrat

210 Sheep tracheal mucus velocity, an in vivo measure of mucocilia

211 eversed the effects of e-cig liquid on sheep tracheal mucus velocity.Conclusions: Our findings show t

212 in relevant biological barriers (mucin/human tracheal mucus, biofilm), leading to complete eradicatio

213 The Drosophila melanogaster embryonic tracheal network is an excellent model to study these pr

214 We identified an undescribed tracheal occlusion (TO) at the posterior extremities the

215 and Scopus databases for clinical studies on tracheal occlusion and CDH.

216 male sex, term birth, high illness severity, tracheal or noninvasive ventilation, parental absence an

217 , mild and attenuated IBV strains in ex vivo tracheal organ culture (TOC).

218 Priming of chicken primary fibroblasts and tracheal organ cultures with chIFN-kappa imparted cellul

219 es in adult chicken kidney cells and ex vivo tracheal organ cultures.

220 ifference between the thoracic and abdominal tracheal organization.

221 ng mouse esophageal organoid units (EOUs) or tracheal organoid units (TOUs) as a model of foregut dev

222 copeltus fasciatus, in which the final adult tracheal patterning can be directly inferred by examinin

223 0 neuronal cell bodies in the ganglia during tracheal perfusion with S1P (10 muM).

224 CFTR(-/-) swine ex-vivo tracheal preparations showed substantially decreased sec

225 Incubating tracheal preparations with inhibitors of epithelial ion

226 hragm dysfunction was evaluated using twitch tracheal pressure in response to bilateral anterior magn

227 PaO2 and PaCO2, minute volume, tracheal pressure, lung aeration measured via CT, alveol

228 clinical setting, a patient who underwent a tracheal reconstruction with a vascularized myofascial f

229 Although there are various methods for tracheal reconstruction, such as a simple approximation

230 , we used a vascularized myofascial flap for tracheal reconstruction.

231 ation, suggesting its suitability for use in tracheal reconstruction.

232 The primary outcome was tracheal reintubation for any cause within 7 days of ran

233 studies, we isolated primary swine nasal and tracheal respiratory epithelial cells and immortalized s

234 esponse to sHA was evaluated in the isolated tracheal ring assay in tracheal rings from TSG-6(-/-) or

235 Rationale: Complete tracheal ring deformity (CTRD) is a rare congenital abno

236 Moreover, TSG-6(-/-) tracheal ring non-responsiveness to sHA was reversed by

237 uated in the isolated tracheal ring assay in tracheal rings from TSG-6(-/-) or TSG-6(+/+), with or wi

238 ontinuous or nearly continuous cartilaginous tracheal rings, variable degrees of tracheal stenosis an

239 of Plk1 also diminished contraction of mouse tracheal rings.

240 ressure of sediment methane to inflate their tracheal sacs.

241 ated with M. hyopneumoniae Matched serum and tracheal samples (to establish the true pig M. hyopneumo

242 Cultured cells repopulated tracheal scaffolds in a heterotopic transplantation xeno

243 The primary objective was to compare the tracheal sealing performance of polyvinyl chloride taper

244 endotracheal tube cuff material and shape on tracheal sealing performance remains debated.

245 ropenem effectively reduced P. aeruginosa in tracheal secretions (p < 0.001).

246 Secondary outcomes were tracheal secretions P. aeruginosa concentration, clinica

247 n alone efficiently reduced P. aeruginosa in tracheal secretions, with negligible effects in pulmonar

248 e (r(s) = 0.46, P = .001) and end-expiratory tracheal shape change (r(s) = 0.40, P = .01).

249 ttenuation, end-expiratory air trapping, and tracheal shape.

250 ation of NM myosin heavy chain on Ser1943 in tracheal SM tissues, which can regulate NM myosin IIA fi

251 sin during contractile stimulation of canine tracheal SM tissues.

252 Tracheal smooth muscle contains significant amounts of m

253 In tracheal smooth muscle ex vivo, in organ baths, isometri

254 and its major constituent alpha-terpinene on tracheal smooth muscle isolated from rats.

255 Contractile stimulation of tracheal smooth muscle tissues stimulates phosphorylatio

256 y electric field stimulation (EFS) in bovine tracheal smooth muscle.

257 85, was enriched in mouse, as well as bovine tracheal smooth muscle.

258 as been demonstrated experimentally that the tracheal sound transmission generates a gain of ~15 dB a

259 Live imaging revealed that tracheal sprouts invade IFMs directionally with growth-c

260 ave been confounded by the low prevalence of tracheal stenosis and a limited number of studies.

261 is indicates a trend toward a higher rate of tracheal stenosis and an increased risk of major bleedin

262 laginous tracheal rings, variable degrees of tracheal stenosis and/or shortening, and/or pulmonary ar

263 significant difference in the prevalence of tracheal stenosis or major bleeding between percutaneous

264 wing percutaneous tracheostomy, particularly tracheal stenosis, are unclear.

265 en to estimate the pooled risk difference of tracheal stenosis, bleeding, and wound infection compari

266 eta-analysis suggests a higher prevalence of tracheal stenosis, wound infection, and major bleeding f

267 es and females (iv), and whether cloacal and tracheal swabs might be used to detect herpesvirus.

268 Drosophila harbour progenitors of the adult tracheal system (tracheoblasts).

269 The diversity in the organization of the tracheal system is one of the drivers of insect evolutio

270 In Drosophila development, tip cells of the tracheal system lead the migration of each branch and co

271 energized gas from the siphon and allows the tracheal system to be pressurized.

272 Here, we used the Drosophila tracheal system to study the complex relationship betwee

273 With a pressurized isolated tracheal system, metabolic gas exchange directly with th

274 ysiological and morphological changes in the tracheal system, metabolic reorganization, and suppressi

275 eling epithelial tissues like the retina and tracheal system.

276 on of the epithelial tubes of the Drosophila tracheal system.

277 sues are supplied by circulatory, neural and tracheal systems throughout the adult lifetime, indicati

278 terrestrial lineages that exchange gases via tracheal systems, most taxa have a dorsal heart that dri

279 branching points in the embryonic and larval tracheal TC leading to cells with extra-subcellular lumi

280 guidance of the subcellular lumen within the tracheal terminal cell (TC) cytoplasm.

281 racheal epithelial cells (TECs) in vitro and tracheal tissue ex vivo in response to virulent strain R

282 tribute to developing applications for human tracheal tissue repair.

283 racheal development.Methods: CTRD and normal tracheal tissues were examined microscopically to define

284 ct on muscarinic force responses in isolated tracheal tissues.

285 lung transplantation, we used an established tracheal transplant model inducing BO-like lesions to in

286 Heterotopic tracheal transplantation (HTT) mouse model was used to e

287 An orthotopic tracheal transplantation model further evaluated the con

288 In functional tracheal transplants, HIF-2alpha deficiency in airway do

289 o acoustic energy that ruptures their dorsal tracheal trunks (DTTs) by the expulsion of gas bubbles i

290 membrane size, which are required for proper tracheal tube elongation.

291 e underlying mechanisms using the developing tracheal tube network of Drosophila indirect flight musc

292 al extracellular matrix proteins involved in tracheal tube size control: Crumbs, Uninflatable, Kune-K

293 Anatomical details of the spiracles and tracheal tubes are described, images presented, and new

294 The total length of the tracheal tubes are seventy times the length of the entir

295 Second, Yorkie controls water tightness of tracheal tubes by transcriptional regulation of the delt

296 Seventy-two ex vivo pig tracheal two-lung blocks.

297 ticles are also shown to be deposited at the tracheal wall for CT-based model, whereas particles are

298 rn-shaped domain, material properties of the tracheal wall, and the thermal processes on the change i

299 ir-liquid interface cultures, and an in vivo tracheal xenograft model.

300 ulti-lineage differentiation in vitro and in tracheal xenografts in vivo.