コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 erties, altering both receptor signaling and trafficking.
2 ogical pathway, retromer-dependent endosomal trafficking.
3 gate KOR homodimerization, localization, and trafficking.
4 f CHC22 have identified new routes for GLUT4 trafficking.
5 erol mimic for the monitoring of cholesterol trafficking.
6 mechanisms by which viruses coopt vesicular trafficking.
7 ement of PIPs in alpha-Syn-mediated membrane trafficking.
8 g amastigotes but not for flagellar membrane trafficking.
9 er promoted migration upon blockade of Golgi trafficking.
10 F302L does not affect KCNA2 subunit membrane trafficking.
11 ex II, and thus had little impact on vesicle trafficking.
12 ssed by inhibiting subcellular mitochondrial trafficking.
13 F302L does not impair KCNA2 subunit surface trafficking.
14 nt functions other than controlling membrane trafficking.
15 EXC-9/CRIP1) that regulates apical endosomal trafficking.
16 s a research tool for inhibiting immune cell trafficking.
17 at is regulated by subcellular mitochondrial trafficking.
18 ) regulation of T cell effector function and trafficking.
19 adds to our understanding of dsRNA virus VF trafficking.
20 ients created by this network promote B cell trafficking.
21 osomal compartments and the dynamics of TfR1 trafficking.
22 QP2, which is critical to regulation of AQP2 trafficking.
23 not interfere with SecYEG-dependent protein trafficking.
24 remodeling ECM in health and disease, their trafficking across the Golgi apparatus remains poorly un
26 various cellular functions, such as vesicle trafficking, activity of the Rab3 and Rab27 small GTPase
28 is most frequently defined in the context of trafficking, analysis of specific migratory behaviors of
30 ld be used to determine the kinetics of cell trafficking and arrest during the earliest phase of the
32 liary alpha2delta subunits of VGCCs modulate trafficking and biophysical properties of the pore-formi
34 a(2+) signaling, actin organization, vesicle trafficking and cell wall deposition, bearing consequenc
37 the cell, with a critical role in endocytic trafficking and endoplasmic reticulum (ER) to plasma mem
38 ns to genes with established effects on CFTR trafficking and function and suggested novel roles of EG
39 ged as an effective corrector that recovered trafficking and function of ATP7B-H1069Q by impairing it
42 ollectively, these discoveries delineate NIS trafficking and highlight the new possibility of systemi
47 Thus, modification of neuronal cholesterol trafficking and of lipid rafts by Nef may contribute to
48 lled Mla has been implicated in phospholipid trafficking and outer membrane integrity, and includes a
50 erone complex, can significantly improve the trafficking and post-ER protein level of diverse NPC1 va
51 ur data identify TSPN6 as a regulator of the trafficking and processing of SDC4 and highlight an impo
53 eric modulator/activator, to rescue K(v)11.1 trafficking and produce functional K(v)11.1 current.
54 hat dofetilide plus LUF7244 rescues K(v)11.1 trafficking and produces functional I(Kv11.1) Thus, comb
55 and becomes associated with known lysosomal trafficking and proteolytic proteins like SQSTM1, CTSD,
59 we report that VAMP3 is essential for viral trafficking and release of infectious progeny, in variou
62 R-associated protein FNDC3A, which regulates trafficking and secretion and, by impairing autophagy, e
63 t PbYOP1's disruption may lead to defects in trafficking and secretion of a subset of proteins requir
66 n prion disease that implicate intracellular trafficking and sphingolipid metabolism as molecular cau
67 ly contribute to increased receptor membrane trafficking and synaptic plasticity during memory recons
68 AMPAR-binding protein shown to regulate the trafficking and synaptic targeting of AMPARs, is require
69 la infection via modulation of endolysosomal trafficking and the vacuolar environment by targeting th
70 dine, interfere with normal K(v)11.1 forward trafficking and thus reduce functional K(v)11.1 channel
72 and differentiation, intracellular membrane trafficking and transport vesicle formation, and nucleoc
73 re they might function to regulate endocytic trafficking and/or the formation or recycling of signali
76 tion, metabolism, nuclear integrity, protein trafficking, and cytoskeletal-microtubule organization,
78 sicular transport systems in reovirus entry, trafficking, and egress and comment on shared themes for
79 aques (RM) and tracked changes in frequency, trafficking, and function of group 3 ILC (ILC3) and NK c
80 P3 somatodendritic A-type channel formation, trafficking, and function, a feature that may be lost in
81 -CSF, a regulator of neutrophil development, trafficking, and function, plays a key role in several n
83 in BCAA catabolism, ROS metabolism, vesicle trafficking, and lipid synthesis while the ovary exhibit
85 ell junction, cilia, cytoskeleton, vesicular trafficking, and regulation of beta-cell epigenetic and
88 regarding the selective recognition, uptake, trafficking, and storage of these elements in biological
93 pact neutrophil numbers in circulation, cell trafficking, antimicrobial defenses, and host well-being
95 ing the regulation of signaling by endocytic trafficking as well as the application of concepts such
96 s work, we used a single-cell flow-cytometry trafficking assay to quantitatively examine the relation
97 we hypothesized that changes in endocytotic trafficking associated with altered APP processing could
98 the inability to control Syt1 expression and trafficking at the presynapse may be key in the transiti
100 ions in the YIPF5 gene, which is involved in trafficking between the endoplasmic reticulum (ER) and t
101 STRIC is independent of canonical vesicular trafficking but requires Arp2/3, suggesting a novel role
102 of RTKs can reciprocally regulate endocytic trafficking by creating feedback loops in cells to enhan
103 data indicate that IRAK-M regulates monocyte trafficking by increasing the expression of CCR2, result
104 is that regulation of growth factor receptor trafficking can be used to promote islet beta cell survi
105 pes (including aspects of motility, membrane trafficking, cell division, and death), but others are m
106 inistration-approved cystic fibrosis protein trafficking chaperone, lumacaftor, has been proposed as
107 ctions with components required for ER-Golgi trafficking, coincident with reduced levels of the prote
109 d administration of LUF7244 and an I(Kv11.1) trafficking corrector could serve as a new pharmacologic
110 valproic acid (VPA) corrects the folding and trafficking defect associated with I1061T-NPC1 leading t
111 keleton remained intact, suggesting that the trafficking defect is not due to defects in actin-relate
113 ts restored trafficking, suggesting that the trafficking defect was due to reduced TRAPPC4 levels.
114 ist, we demonstrated gain-of-function of the trafficking defect, suggesting the possibility of rescui
118 rected both congenital and acquired K(v)11.1 trafficking defects, resulting in functional K(v)11.1 cu
119 lide, rescue congenital and acquired forward trafficking defects, this is of little use because of th
121 In order to provide new information on VF trafficking during dsRNA virus coinfection, we rescued t
123 essential role of GRIP1 in regulating AMPAR trafficking during synaptic plasticity and learning and
125 ted self-assembly of a synthetic peptide for trafficking endogenous proteins, this work provides insi
127 eral important functions of these latter two trafficking events have been identified, yet the pathway
128 ocessing, enhancing TCR-T effector function, trafficking, expansion, persistence, and memory formatio
130 expression of several metabolic and protein trafficking factors, including RAB27B, at the onset of i
131 at duplications in cytoskeletal and membrane-trafficking families were among the earliest events, whe
132 te that beta-coronaviruses utilize lysosomal trafficking for egress rather than the biosynthetic secr
134 any iron-sulfur proteins involved in cluster trafficking form [2Fe-2S]-cluster-bridged complexes that
136 STING carbonylation at C88 and inhibited its trafficking from the endoplasmic reticulum (ER) to the G
137 visiae, we uncover a novel group of proteins trafficking from the ER to the early Golgi apparatus.
141 e discovered a large number of endolysosomal trafficking genes required for proper SG maturation, ind
145 in lipid signaling (PLDdelta), endomembrane trafficking, hormone, light, and receptor signaling, and
146 e development and facilitate polarized cargo trafficking; however, the mechanism that regulates dendr
147 plant trans-Golgi network (TGN) is a central trafficking hub where secretory, vacuolar, recycling, an
148 periments focused on protein interaction and trafficking identified CLN6 as an obligate component of
154 hnique will enable the exploration of biotin trafficking in humans and its use as a research tool for
156 o-null Foxo1 exhibited Akt-dependent nuclear trafficking in mouse CD8 T cells and augmented the expre
158 ryotes and highlights ways in which membrane trafficking in protists differs from that in our well-un
161 rtance of tetraspanin-mediated intracellular trafficking in the regulation of BMP signaling in vivo.
166 cellular functions beyond nucleocytoplasmic trafficking, including genome organization and gene expr
168 r, wortmannin, an inhibitor of intracellular trafficking, inhibited mycobactericidal activity, but as
169 Angiotensin II (Ang II) stimulation induced trafficking into and out of lipid rafts/caveolae for Nox
170 proto-oncogene c-Met (MET), and shunts their trafficking into late endosomes and lysosomal degradatio
173 ol and LAMP-1, suggesting that viral protein trafficking is mediated by LAMP-1-positive vesicles in a
177 the inability to control Syt1 expression and trafficking may be key in the transition from loss of SV
179 000 chaperones, quality control factors, and trafficking mechanisms collectively termed the proteosta
180 Fs, this initial regulatory step of membrane trafficking might well occur in eukaryotes in general.
181 fecycle, including multivesicular body (MVB) trafficking, MVB fusion, exosome uptake and endosome aci
182 Here, we analyzed host genes involved in trafficking networks to examine their involvement in nai
183 Tollip regulates Parkin-dependent endosomal trafficking of a discrete subset of mitochondrial-derive
184 ovel role for CRT in promoting the secretory trafficking of a protein that forms polymers and large i
186 synaptic potentiation by increasing the net trafficking of AMPARs into spines, including in non-moto
187 ng of the factors that control the secretory trafficking of ATZ and their regulation by CRT could lea
189 ctional defect of these mutations is reduced trafficking of bestrophin-1 into the plasma membrane.
191 vesicle coatomer, which regulates retrograde trafficking of cargo between the Golgi apparatus and the
194 on during synaptic transmission mediates the trafficking of chemical signals and neuronal communicati
195 ript, we show that CCB is involved in axonal trafficking of FasII and synaptobrevin, but not syntaxin
198 the determinants governing the intracellular trafficking of Gag-gRNA complexes and their accumulation
203 arliest phase of the metastatic cascade, the trafficking of immune cells during cancer immunotherapy
204 further show that CLASP2 is required for the trafficking of incoming HIV-1 particles carrying wild-ty
205 elta phenotype may arise from alterations in trafficking of iron directly from cytosol to mitochondri
206 ictates nuclear transport, regulates ciliary trafficking of KAP3, a key component for functional kine
207 gross morphology of hair bundles and proper trafficking of known MET components Protocadherin 15a (P
208 te', is specialized for gas exchange and the trafficking of leukocytes, and is unique to the lung.
210 ere we show that ILK is necessary for normal trafficking of melanosomes along microtubule tracks.
211 al to vision occur within the IPM, including trafficking of nutrients and metabolites, retinal attach
212 e evaluate the role of syntaxin 3 (STX3), in trafficking of OS membrane proteins such as peripherin 2
213 nt in neuronal axons, although long-distance trafficking of palmitoyl-proteins is important for axon
214 define tools for studying the intracellular trafficking of pathogens elicited by inhibition of PIKfy
218 well-known chemical chaperone that improves trafficking of several transmembrane proteins, restored
219 abilized with a semipermeable membrane allow trafficking of single-stranded DNA between neighboring p
222 fication of the erythrocyte cytoskeleton and trafficking of the adhesin and key virulence factor PfEM
223 a scaffold protein; Hsp70 chaperone-mediated trafficking of the cluster and insertion into [2Fe-2S] t
225 KHARON as being important for both flagellar trafficking of the glucose transporter GT1 and for succe
226 membrane mobilisation, cargo engulfment and trafficking of the newly formed autophagic vesicle to th
228 mework design, TM-based catalyst design, the trafficking of TM ions in biological systems, and drug d
229 initiate action potentials and regulate the trafficking of vesicles between somatodendritic and axon
231 CR4 receptor that increases mobilization and trafficking of white blood cells from the bone marrow.
233 ns and various effector proteins involved in trafficking or fusion events, whereas those at the inner
234 iquitinases that are either linked with GPCR trafficking or localized on endosomes, we identified sig
235 rs and may therefore play a role in receptor trafficking or synaptic anchoring, a function thus far o
236 potentially facilitates vesicle formation by trafficking PA and/or PIP, known regulators of membrane
237 Here, we identify a mitochondrial protein trafficking pathway in Drosophila melanogaster involving
238 ts suggested that (i) Pompe cells lack a VZV trafficking pathway within M6PR-positive large endosomes
239 tern-triggered immunity and the MIN7 vesicle-trafficking pathway, or a constitutively activated cell
240 ochemical signaling networks control vesicle trafficking pathways and how their nonequilibrium proper
241 GTPase that regulates a number of endosomal trafficking pathways including retrograde transport to t
246 sttranslational modification and subcellular trafficking, potentially resulting in selective vulnerab
249 NIFICANCE STATEMENT SORLA is a transmembrane trafficking protein previously known to reduce the level
250 velopment of hypertension and imply that the trafficking protein SNX1 may be a crucial determinant fo
252 arify our current understanding of endocytic trafficking, providing significant additional insight in
258 ed in the spaciotemporal regulation of GLUT4 trafficking represent potential therapeutic targets for
259 This modification corrected R-Ras membrane trafficking, restored fibronectin processing, increased
260 n late endosome morphology and endosomal LDL trafficking, resulting in cellular cholesterol deficienc
262 of interferon production, while an alternate trafficking route delivers it directly to the autophagos
264 g data provided by the decoys, we identified trafficking routes and on two occasions properties of po
265 d show changes in genes enriched for protein trafficking, splicing, regulation of apoptosis, and prev
266 d-type TRAPPC4 in these fibroblasts restored trafficking, suggesting that the trafficking defect was
269 (HEV), thereby attributing their inefficient trafficking to alterations in the subsequent transendoth
270 herapeutic target, including its biogenesis, trafficking to and from the plasma membrane, and how the
272 is selectively required for effector T cell trafficking to inflamed tissues, without affecting naive
274 s are important for SERINC5 down-regulation, trafficking to late endosomes, and exclusion from newly
275 rotein biochemical interactions with vesicle trafficking to probe how various processes might affect
276 -glycosylated, but beyond regulating protein trafficking to the cell surface, whether and if so how t
278 ling attenuated both monocyte and neutrophil trafficking to the CP and cortex.SIGNIFICANCE STATEMENT
279 bit an activated phenotype and be capable of trafficking to the lungs where their presence was aligne
282 a strong correlation between CD63(+) vesicle trafficking to the plasma membrane and focal adhesion dy
283 ad a cytotoxic phenotype and were capable of trafficking to the tumor and mediating cell killing.
284 ctional expression of an acyltransferase via trafficking to the vacuole, heterologous transporters to
285 and RAB8A are important regulators of HIV-1 trafficking to the VS and therefore the infection of CD4
287 cells include severe toxicities, restricted trafficking to, infiltration into and activation within
288 ment epithelial cells to facilitate retinoid trafficking, to prevent nonspecific reactivity, and to c
289 eptors mediates protein binding and receptor trafficking, ultimately controlling synaptic transmissio
291 treatment such as inhibition of immune cell trafficking versus immune cell depletion, thereby substa
292 o families of small GTPases through membrane trafficking via regulation of the prenylation pathway.
293 in the endoplasmic reticulum to folding and trafficking via the secretory pathway, optimization of a
294 well as functional clathrin-mediated vesicle trafficking were essential for the maintenance of VAMP4-
295 oscopy and characterized LVS intramacrophage trafficking when co-cultured with immune lymphocytes.
296 rect alterations in both Syt1 expression and trafficking when expressed in the absence of endogenous
297 namin, clathrin, sorting endosomes and Golgi trafficking where the cargo is released intracellularly.
298 cate that ALK regulates dopamine D2 receptor trafficking, which has implications for psychiatric diso
299 es in postsynaptic neurotransmitter receptor trafficking, which is essential for synaptic plasticity.