ライフサイエンスコーパス: trait

1 isgust sensitivity, and Big Five personality traits).

2 (LD) score-based enrichment testing for each trait.

3 F indicate a complex genetic encoding of the trait.

4 te gene associated with the aspartate uptake trait.

5 standing of differences in a key demographic trait.

6 nstruct genetic instruments for plasma lipid traits.

7 a through acquisition of positively selected traits.

8 viduals with varying levels of autistic-like traits.

9 ood present different underlying personality traits.

10 estigating evolutionary pressures on complex traits.

11 re associated with gene expression and human traits.

12 tic glucosinolates (GLS) and the Gln-related traits.

13 onses to interspecific coordination of plant traits.

14 impact the evolutionary trajectory of floral traits.

15 iology between aggression and these three CU-traits.

16 nderstanding the evolution of key land plant traits.

17 between knockout-mutations and all AraPheno traits.

18 e, driven by variations in eco-physiological traits.

19 affected the general age trajectory of some traits.

20 cases with more than two possibly correlated traits.

21 nutritional quality and additional consumer traits.

22 redisposition shared with neuropsychological traits.

23 field phenotyping for seed, shoot, and root traits.

24 mechanisms underlying the diversification of traits.

25 genetic correlations between BE/EA and other traits.

26 ion of LNJ in barley and rice caused similar traits.

27 bservations, on cell morphology and swimming traits.

28 well as in studies of commercially important traits.

29 quence of the optimisation of photosynthetic traits.

30 merous genes that co-varied with behavioural traits.

31 ns to summary-level GWASs data of 33 complex traits.

32 for ADHD both were associated with autistic traits.

33 ns (p < 0.001) for all assessed quantitative traits.

34 iants can cause diseases or alter phenotypic traits.

35 ample sizes, heterogeneous noise, and binary traits.

36 les were much more variable in immunological traits.

37 measured host growth benefits and functional traits.

38 plant and leaf morphology) and leaf ionomic traits.

39 omic information into a catalog of microbial traits.

40 esent additional association signals for the traits.

41 sm that simultaneously maximizes all fitness traits [1].

42 cording to a normally distributed and stable trait ability (hypnotisability).

43 erican individuals to predict soft biometric traits about the donors.

44 Nevertheless, such traits also were sorted along other environmental cues,

45 The genome-wide cross-trait analysis features in several analytic aspects: gen

46 Most multi-trait analysis methods focus on individual common varian

47 Several publications have examined leaf-trait and carbon-cycling shifts along an Amazon-Andes tr

48 nipulated in order to control this important trait and further allow the development of molecular mar

49 The relation between autistic traits and brain mechanisms underlying spontaneous eye c

50 c and brain-specific Basenji-H3K4me3 for all traits and brain traits respectively.

51 ironmental change influences fitness-related traits and demographic rates, which in herbivores are of

52 etic variants exert their effects on complex traits and disease.

53 Assessing the causal tissues of human traits and diseases is important for better interpreting

54 aspects of the genetic architecture of human traits and diseases.

55 ecords and extensive databases of functional traits and distribution patterns to understand the respo

56 ned with data on six agronomically important traits and from genotyping-by-sequencing.

57 ediate the spread and maintenance of diverse traits and functions in microbial communities.

58 been previously linked to fasting glycaemic traits and insulin resistance in genome wide association

59 The highly polygenic nature of quantitative traits and most common phenotypes has motivated the deve

60 species and explore links between migratory traits and predation risk.

61 understanding of the genetic control of key traits and relationships among individuals in cherry.

62 ders evidence pertaining to three continuous traits and six domains of disease.

63 An association between pathogen life history traits and the demographic competence of faster-living h

64 on between Mendelian inheritance of discrete traits and the genetically based correlation between rel

65 coordinated relationships between plant leaf traits and their capacity to predict ecosystem functions

66 For both pairs of species, species-specific traits and their genomes regressed to those of the conti

67 represented pathways were often shared among traits and were consistent with biological knowledge (e.

68 getated pixels had reasonable values for one trait, and 28-81% provided high confidence for multiple

69 are proposed to contribute to human-specific traits, and more than 40 tandem repeat expansions are kn

70 ered syndromes comprised of many interacting traits, and that elucidating the genetic basis of these

71 uitry may underlie individual differences in trait anxiety using the common marmoset (Callithrix jacc

72 while positive affect remained elevated, and trait anxiety was reduced.

73 r which molecular endophenotypes and complex traits are assessed on the same genotypes.

74 Our analyses reveal that not all traits are equally well-suited for reconstructing popula

75 Common and complex traits are the consequence of the interaction and regula

76 However, many of these traits are unavailable in archaeological and fossil indi

77 Species traits are widely used in ecological and evolutionary sc

78 Foliar functional traits are widely used to characterize leaf and canopy p

79 nts, water use efficiency (WUE) is a complex trait arising from numerous physiological and developmen

80 sociated with numerous ecologically relevant traits, as well as soil and climate characteristics.

81 However, only combinations of traits associated more directly with plant functional pr

82 Traits associated with classical mutants were consistent

83 lts identify new molecular and morphological traits associated with pericyte maturation and uncover P

84 , we have identified intracellular metabolic traits associated with the 1q25 risk allele in HUVECs, i

85 hstand drought is likely to be determined by traits associated with their hydraulic systems.

86 taling 5019 unique GWAS data sets and 15 770 trait-associated gene sets.

87 iseases is important for better interpreting trait-associated genetic variants, understanding disease

88 ificant single nucleotide polymorphism (SNP)-trait associations, which leads to high sequencing cost.

89 independent association signals for 459 cell traits at 70 loci (53 of them novel) identifying several

90 s gap by incorporating the habitat selection traits at different flows of a freshwater apex predator,

91 ified LD score regression to 41 diseases and traits (average N = 320K), conditioning on a broad set o

92 Based on 31 studies of complex human traits (average sample size 136,000), we show that the B

93 to understand the molecular basis of imaging traits based on the interpretation of what the neural ne

94 Using a trait-based approach that incorporated genomic and pheno

95 decomposition ability by combining detailed trait-based assays on 34 saprotrophic fungi from across

96 corporating such theory into next-generation trait-based terrestrial biosphere models would improve p

97 Here we examine which traits best explain fungal decomposition ability by comb

98 volutionary process that drives a phenotypic trait beyond a tipping point, thereby resulting (after a

99 dy the effect of gene variants on phenotypic traits, but the Cre/loxP and Tet-On/Tet-Off systems can

100 fe consequences of this key plant functional trait by demonstrating that its effect on decay depends

101 sed to jointly interrogate genome on complex traits by integrating both the GWAS dataset and the expr

102 isms associated with the regulation of these traits by Q, especially for the structural determination

103 hanisms involved in the improvement of fruit traits by the grafting of watermelon and bottle gourd.

104 We demonstrate that plant traits can predict mean annual tree growth rates with mo

105 ng the propagation of these predator-induced trait changes through particular communities remains a c

106 g a probabilistic computational model, while trait cognitive anxiety symptoms are associated with enh

107 'least-cost' theory posits that the optimal trait combination for a given environment is that where

108 ions reflect convergence towards predictable trait combinations, indicating that morphological variat

109 28-81% provided high confidence for multiple traits concurrently.

110 r hypothesis, species from drier summers had traits conferring more tolerance to drought such as smal

111 en revealed that these changes in phenotypic traits constrain recovery of basic ecosystem functions (

112 ly correlated with scores of the personality trait constraint independent of sex or age.

113 models to quantify region-specific trends in trait coordination and trait responses to climate gradie

114 ensive screen measures thousands of pairwise trait correlations across hundreds of thousands of yeast

115 on-consumptive effects tightened behavioural trait correlations in wild-caught stickleback from high-

116 we introduce a new framework for quantifying trait correlations, phylogenetic constraints and spatial

117 fied a subset of available macroinvertebrate traits, corresponding to a life-history model with axes

118 We show strong regional patterns of trait covariation across the shared ranges of Th. couchi

119 sing amplicon sequencing, we combine initial trait data measured for each species separately and meta

120 phenology and environmental data, analysing trait data within a context of three widespread, adaptiv

121 D+CU, N=198) and without callous-unemotional traits (DBD only, N=276).

122 bdivided into those with callous-unemotional traits (DBD+CU, N=198) and without callous-unemotional t

123 only participants low on callous-unemotional traits demonstrated increased gun carrying as a function

124 Traits differ significantly among localities, with lower

125 We mapped this trait difference to a single genomic region and, using t

126 Despite growing evidence for intraspecific trait differences, it remains unclear under which circum

127 as long been recognised as a major driver of trait divergence and adaptive evolution, relatively litt

128 Variation in leaf traits due to VPC are likely to provide distinct benefit

129 We found age-dependent changes in five song traits (duration, maximum frequency, peak frequency of s

130 to an interplay of predisposing personality traits (e.g., impulsivity), and reductions in cognitive

131 ptera and R. moelleri shared only two unique traits each with widespread boreal-Arctic R. palpebrosa.

132 Plasmids can horizontally transmit genetic traits, enabling rapid bacterial adaptation to new envir

133 wever, the rules governing the repertoire of traits encoded on MGEs remain unclear.

134 results showcase the key role of plant root traits, especially root diameter, root nitrogen and spec

135 s problem, as it provides data on repetitive trait evolution between lineages [4, 8].

136 affective lability, aggressive or impulsive traits explain childhood trauma's effects on SI variabil

137 male variability was found in morphological traits, females were much more variable in immunological

138 ars (varieties) with high diversity in a key trait for climate change adaptation-phenology.

139 Consistency can make behavior an adaptive trait for mate choice decisions.

140 esistance to cavitation (P(50) ), a critical trait for predicting survival during drought, had highly

141 need for FACE investigations of the value of traits for drought adaptation to be conducted under more

142 are some of the most diverse and conspicuous traits found in nature and have been widely studied from

143 and (2) variation in selection that prevents traits from becoming fixed, which together generate self

144 indicate that growth is a complex polygenic trait governed by carbon and energy partitioning.

145 years of second season field trials for the traits grain yield, number of ears, and grain moisture.

146 n-fixing clade indicated that the nodulation trait has a shared evolutionary origin in all 10 lineage

147 sociations between distinct loci and various traits have been successfully discovered and published f

148 Diverse traits have evolved through cis-regulatory changes in ge

149 ective polymorphisms-such as the sickle-cell trait-having been selected to high frequencies in malari

150 ents revealed strong broad- and narrow-sense trait heritability (0.82 and 0.41, respectively).

151 rent genomic regions play different roles in trait heritability and which region is more responsible

152 r costs and the relationship with functional traits highlight the nuanced relationships between speci

153 s of different pomological and nutraceutical traits, identifying cultivars with antioxidant activity

154 Here, we sought to examine how trait impulsivity and acute stress exposure affect parti

155 y among these loci and those controlling the trait in other species.

156 early during the evolution of rapid cycling trait in rice subspecies.

157 finger protein, controls the stem solidness trait in wheat.

158 ts that problem-solving is a stable, general trait in wild spotted hyenas.

159 ns-ethnic meta-analyses for 15 hematological traits in 746,667 participants, including 184,535 non-EU

160 ined by adult-based GRSs for disease-related traits in adolescents, although still relatively modest,

161 The importance of complex traits in biology and medicine has motivated diverse app

162 n proteins associated with echocardiographic traits in cross-sectional analyses (false discovery rate

163 had pQTLs associated with echocardiographic traits in EchoGen (P<0.0007).

164 The growing use of functional traits in ecological research has brought new insights i

165 as the only factor associated with fine-root traits in statistical models including mycorrhizal assoc

166 standing of how selection acts on key floral traits in taxonomically diverse species, and that furthe

167 ation in telomere length impacts hematologic traits in the population.

168 association studies (GWAS) of complex human traits in the UK Biobank has not been investigated.

169 om gene expression data with five methods as traits in trans-eQTL analysis to limit multiple testing

170 thways in plants and regulate many agronomic traits, including architecture and grain yield.

171 editing can rapidly improve a range of crop traits, including disease resistance, abiotic stress tol

172 mids encode diverse niche-adaptive accessory traits, including multidrug resistance; 3) the accessory

173 Growth is a complex trait influenced by multiple genes that act at different

174 horizontal and likely confounded by a third trait influencing education.

175 This dominant trait is conferred by the SSt1 locus on chromosome 3B.

176 man gene to specific functions, diseases and traits is a grand challenge in modern genetics.

177 Our work suggests that targeting cooperative traits is a viable solution to the problem of antimicrob

178 iology, and tracing the evolution of complex traits is an open problem.

179 nce that the presence of higher compulsivity traits is associated with an atypical profile of this de

180 that elucidating the genetic basis of these traits is required to assess models of evolution and to

181 information on parrot distributions, species traits, IUCN assessment, habitat loss and timber extract

182 Host relatedness and traits known to promote vector exposure neither predicte

183 h predominantly impaired clinical state- and trait-level phenotypes, while pointing toward an interac

184 lity to different causes of mortality due to traits, life history stages, or locations.

185 eight (7-25%), without altering seed quality traits like fatty acid composition, glucosinolates, oil

186 rocesses, rather than more commonly employed traits like wood density or leaf mass per area, yield th

187 which patterns of hyporeactivity represent a trait-like indicator of depression and which represent a

188 ty changed over time, suggesting it might be trait-like, at least over 2 years.

189 anxious temperament (AT), reveals that it is trait-like.

190 he effects of paleoclimates and life history traits likely tangled with the effects of human-mediated

191 wer of brain-related expression quantitative trait loci (eQTL) and allele-specific expression (ASE) s

192 GWAS dataset and the expression quantitative trait loci (eQTL) dataset.

193 and tissue-specific expression quantitative trait loci (eQTL) information to help annotate a set of

194 ecific epigenome and expression quantitative trait loci (eQTL) to identify susceptibility genes/varia

195 tify pMEI-associated expression quantitative trait loci (eQTLs) and splicing quantitative trait loci

196 52 and rs6004160 are expression quantitative trait loci (eQTLs) of CRKL.

197 Three quantitative trait loci (QTL) for delta(13) C(leaf) were found and co

198 tasets, genome-wide significant quantitative trait loci (QTLs) associated with weight and length were

199 In this study, we mapped the quantitative trait loci (QTLs) of m(6)A peaks in 60 Yoruba (YRI) lymp

200 genetic mapping to identify the quantitative trait loci (QTLs) that mediate how leaf area scales with

201 trait loci (eQTLs) and splicing quantitative trait loci (sQTLs) in 48 tissues.

202 Expression quantitative trait loci analyses identified multiple SNPs associated

203 RNA sequencing, and expression quantitative trait loci data.Measurements and Main Results: We discov

204 s to map hundreds of expression quantitative trait loci that influence expression dynamically during

205 An enrichment of expression quantitative trait loci was detected among the CC-susceptibility vari

206 On the other hand, chromatin quantitative trait loci, elucidated by direct epigenetic profiling of

207 rt-based DNA methylation (DNAm) quantitative trait locus (mQTL) studies to predict PAIs.

208 tral USA for 3 yr and conducted quantitative trait locus (QTL) mapping for rust progression.

209 f qFIRM SKIN 1 (qFIS1), a major quantitative trait locus that partially determines the difference in

210 ctive closeness to each target and their own trait loneliness.

211 Across all trait maps, 90% of vegetated pixels had reasonable value

212 We hypothesized that this individual-level trait may drive GII.4 norovirus predominance at the huma

213 systems suggests that similar coevolution of traits may be found in other ectothermic animals with hi

214 nes in avian song, and possibly other sexual traits, may be more common than currently known, and may

215 analytic aspects: genetic correlation, cross-trait meta-analysis, Mendelian randomization, polygenic

216 Furthermore, callous-unemotional traits moderated the relationship between peer gun carry

217 cales by combining openly available species' trait, occurrence and phylogenetic data with gridded, hi

218 dels appear to play little or no role in the traits of an organism.

219 The epigenetic traits of cancer cells and of associated tumor microenvi

220 power of comparative genomics to understand traits of importance to Andropogoneae grasses.

221 Other unique traits of the G. margarita genome include the expansion

222 eral distinct genes that determine different traits of the syndrome and are held together, because re

223 light-environment-mediated variation in the traits of their host plants is central to our understand

224 Here we test whether above- and below-ground traits of tropical tree seedlings could explain observed

225 hy adult dogs and the effects of physiologic traits on these patterns of activity.

226 This theory elaborates on how a particular trait once favoured in an ancient environment might beco

227 nterest of many investigators is identifying traits or diseases that share common susceptibility loci

228 hanges in productivity, (ii) exotic species' traits, or (iii) novel (non-coevolved) biotic interactio

229 sequence variants that influence biomedical traits, particularly those related to the onset and prog

230 nome sampling can severely confound discrete trait phylogeographic inference.

231 ome-wide multilocus analysis of longitudinal traits possible.

232 ctive lability, and aggressive and impulsive traits predicted greater SI variability.

233 f Arctic species compositions and functional trait profiles and diversity, thereby affecting ecosyste

234 Heritability of passive immunity associated traits (range 0.02-0.22) and the disease traits (range 0

235 ted traits (range 0.02-0.22) and the disease traits (range 0.03-0.20) were low-to-moderate.

236 ncorporate features of disturbances, species traits, rapid evolution and dispersal.

237 Our results thus demonstrate rapid trait refinement and adaptation to the new citrate niche

238 We measured functional traits reflecting leaf metabolism and associated with gr

239 performance in our task, but do find autism trait related differences in learning rate parameters.

240 We also included several agro-morphological traits related to leaves, stems and roots with high heri

241 These findings suggest robust interspecific trait relationships under global changes, and call for l

242 Linking genomic variation to phenotypical traits remains a major challenge in evolutionary genetic

243 2 cm(2) , pairing multiscale statistics with traits representing axes of resource transport, damage r

244 These lifestyle-specific traits require integration into the regulatory network o

245 We examined whether a key psychological trait-resilience, defined as one's ability to recover qu

246 fic Basenji-H3K4me3 for all traits and brain traits respectively.

247 on-specific trends in trait coordination and trait responses to climate gradients.

248 lections can be used to broadly characterize trait responses to environment, revealing heterogeneity

249 gh which we can understand how tree size and traits shape growth responses to droughts.

250 opment can bias the independent evolution of traits sharing ontogenetic pathways, making certain evol

251 Hydraulic traits showed no adjustment following 15 years of experi

252 ng program involve the evaluation of several traits simultaneously in a large set of target environme

253 ed on multiple factors including woody plant traits, site level climate, and abiotic soil conditions.

254 etland plants in general show a shift within trait space along the same common slope as observed in n

255 rlap between botanical races in multivariate trait space indicates that the phenotypic range of each

256 WAS and 36% (s.e. 4%) more powerful than the trait-specific maximum of GWAS and GWAX, based on the nu

257 In nature, it remains unclear how defensive traits such as crypsis, activity levels and speed influe

258 ng behaviour is shaped by animal personality traits, such as boldness.

259 , leading to changes in complex life history traits, such as longevity.

260 s of the QTLs of m(6)A and related molecular traits suggests that the downstream effects of m(6)A are

261 ntal cues, showing multidimensional adaptive trait syndromes.

262 , higher on self-report measures of autistic traits, systemizing, and sensory sensitivity, and, on av

263 Although plasticity is a valuable trait that allows the human brain to rewire and recover

264 Organ size is a major agronomic trait that determines grain yield and biomass production

265 ime is a complex, environmentally responsive trait that has critical impacts on plant fitness, crop y

266 Early vigour in wheat is a trait that has received attention for its benefits reduc

267 nent of behavioral inhibition, a personality trait that is a risk factor for anxiety disorders.

268 eciose but also because species have evolved traits that allow them to locally co-occur.

269 can be substantially affected by changes in traits that are variable under environmental stochastici

270 Identifying traits that convey resilience to OA is critical to the c

271 umber is one of the most important agronomic traits that determine rice (Oryza sativa) yield.

272 the biosynthesis of these crucial phenotypic traits that have greatly impacted insect behavior, physi

273 g, this is likely to affect the evolution of traits that mediate social conflict.

274 In contrast to fitness traits, the amount of genotype by environment interactio

275 reported in the literature for many complex traits, the non-transferability of polygenic risk scores

276 lopment of molecular markers to utilise this trait to exploit homoeologous recombination in a crop.

277 ng ecological theory that predicts different traits to be favored under varying environmental conditi

278 sition, demonstrating the potential for root traits to be used within predictive frameworks of plant-

279 with some symbiotic bacteria having evolved traits to invade the epithelial mucus layer and reside d

280 ncy can explain the maintenance of atavistic traits under domestication.

281 nt drivers of the change in plant functional traits under warming climate, but studies on one key fac

282 measurements, we developed grass functional trait values (physiological, structural, biochemical, an

283 edict differences in disease risk or complex trait values between siblings is a strong test of genomi

284 osystem functioning were mediated by thermal trait variability.

285 535 non-EUR individuals, we identified 5,552 trait-variant associations at p < 5 x 10(-9), including

286 Trait variation along geographic gradients provides a co

287 ldlife, such as poor control and substantial trait variation within and among species.

288 Each trait was associated with different single nucleotide po

289 rrelation between relatives for quantitative traits was Fisher's infinitesimal model of a large numbe

290 By contrast, the decrease in antipredator traits was stronger for gregarious, urbanized species, a

291 l accounts for variations in all the spindle traits we studied here, both within species and across n

292 To test the effect of diet on life-history traits, we tested how diet composition affects innate im

293 ldren were 6 years of age, asthma and atopic traits were diagnosed by pediatricians.

294 227) of Barbary macaques' social and health traits were related to the macaques' facial morphology a

295 whether tropical trees can adjust hydraulic traits when experiencing drought remain rare.

296 election of the parasite's host-manipulating trait, which facilitates transmission of the recipients

297 uppress isoprene emission, we show that this trait, which is thought to be required for the tolerance

298 a (ELSA), identifying genes controlling this trait will shed light on our understanding of plant grow

299 and Arctic endemic R. moelleri shared three traits with each other, while both R. megaptera and R. m

300 larifying the coordination of leaf hydraulic traits with gas exchange across closely-related species