ライフサイエンスコーパス: trans-acting

1 e catalytic activity, which is predominantly trans acting.

2 aracterization, and application of versatile trans-acting 2'-5' adenylyl transferase ribozymes for co

3 t and remain unmethylated in the presence of trans-acting 24-nt siRNAs can nevertheless acquire methy

4 orescence studies suggest that both cis- and trans-acting 3D molecules localize to the same cellular

5 Trans-acting aberration hotspots were found to modulate

6 px RNA activates Xist expression through its trans-acting ability to evict CTCF from Xist promoter.

7 "R-hand" motif (R(x)D(xxx)R) needed for its "trans-acting" activity.

8 slation could be specifically enhanced using trans-acting agents that counter the function of negativ

9 ticularly complex, consisting of cis-acting, trans-acting and, surprisingly, compensatory cis-trans e

10 e side-chain conformation of residue R359, a trans-acting arginine-finger residue essential for ATP h

11 ncluding ClpB/Hsp104, possess a pair of such trans-acting arginines in the N-terminal nucleotide bind

12 The requirement of the three trans-acting AT domains for the biosynthesis of the macr

13 However, use of a standalone trans-acting AT to complement modules with catalytically

14 g of somatic genes is attributable to either trans-acting cellular environment or cis-acting chromati

15 his is the first description of a role for a trans-acting cellular protein in PRF.

16 ved that cis-regulatory changes often oppose trans-acting changes affecting the same genes, suggestin

17 her determined the contributions of cis- and trans-acting changes in splicing regulatory networks by

18 We also identified cis- and trans-acting chromatin contacts to other genomic regions

19 es, with the landscape dominated by cis- and trans-acting CNAs.

20 length elements, able to encode the cis and trans acting components of the retrotransposition machin

21 th well-established roles in RNA biology, as trans-acting components of the mRNP.

22 e globin genes is regulated by many cis- and trans-acting components.

23 To quantify cis- versus trans-acting contributions to mammalian regulatory evolu

24 cleavage of single-strand RNA (ssRNA) by the trans-acting Csm6 RNase.

25 e rebuilt structures to a higher resolution, trans-acting deoxy-inhibited structure of the ribozyme,

26 what we believe to be a novel in cis- and in trans-acting DNA and lncRNA regulatory feedback element

27 or the presence of histone modifications and trans-acting DNA binding proteins using chromatin immuno

28 Trans-acting DNA variants may specifically affect mRNA o

29 tion, or stability of co-transcribed RNA, or trans-acting, e.g. small regulatory RNAs, which target s

30 This trans-acting effect involves SUZ12, reflecting interacti

31 sruption of these prophages had a widespread trans-acting effect on the transcriptome.

32 he terminal repeat (TR) element and requires trans-acting elements, both viral and cellular, such as

33 ty is likely due to changes in both cis- and trans-acting elements, hinting at widespread and frequen

34 he understanding and use of novel, versatile trans-acting elements.

35 ent an important class of sequence-specific, trans-acting endogenous small RNA molecules that modulat

36 Moreover, trans-acting endoribonucleases, Csx1 or Csm6, can promot

37 LovC is a trans-acting enoyl reductase (ER) that specifically redu

38 mplex process reliant on the coordination of trans-acting enzymes to produce functional ribosomal sub

39 We identified cis-acting and trans-acting eQTL for key immune and metabolic response

40 region, transcript/exon-level and cis versus trans-acting eQTL, across 10 regions of the human brain.

41 large number of infection-specific cis- and trans-acting eQTLs in the DGRP, including one common non

42 regions, as well as being cis-acting; (iii) trans-acting eQTLs tend to have larger effects on expres

43 Such trans-acting ERs have been reported across a variety of

44 ignment indicates a general applicability to trans-acting ERs of fungal PKSs, as well as their potent

45 We also identify approximately 300 trans-acting evQTL between >13,000 common SNPs and 500 r

46 Although trans-acting expression quantitative trait loci (trans-e

47 ontrolled by transcription factors driven by trans-acting expression quantitative trait loci.

48 esponse can be explained by a single cis- or trans-acting expression quantitative trait locus (eQTL).

49 identify and describe a role for FANCD2 as a trans-acting facilitator of CFS replication, in the abse

50 gs are consistent with NCL acting as an IRES trans-acting factor (ITAF) for ORF2 translation and henc

51 mportant internal ribosome entry site (IRES) trans-acting factor (ITAF) for poliovirus IRES-mediated

52 ion-dependent CNSHA caused by mutations in a trans-acting factor (Kruppel-like factor 1) and reveal a

53 We have further identified key trans-acting factor binding sites and nuclear factors AP

54 Trans-acting factor binding to small DNA motifs (cis-ele

55 ow that Zar2 contains a zinc finger and is a trans-acting factor for the TCS in maternal mRNAs in imm

56 their biogenesis is partially dependent on a trans-acting factor FPA.

57 al mediator of this transport process is the trans-acting factor heterogeneous nuclear ribonucleoprot

58 Such a dual-targeted trans-acting factor provides a means to coregulate the e

59 e provide evidence that the abundance of the trans-acting factor that binds the LdNT3 stem-loop in vi

60 says, we discovered that Sam68 is a possible trans-acting factor that binds to this region and regula

61 nizes the glucocorticoid receptor as a novel trans-acting factor that regulates CFTR expression in vi

62 nscripts, suggesting that PCBP1 can act as a trans-acting factor to stabilize sortilin transcripts.

63 ivery of the corresponding cognate synthetic trans-acting factor ZF6-DB without the intrinsic transcr

64 ng the interaction of a requisite c-MYC IRES trans-acting factor, heterogeneous nuclear ribonucleopro

65 gent cadicivirus IRESs require the same IRES trans-acting factor, poly(C)-binding protein 2 (PCBP2).

66 ne if Spn1 causes a fitness defect through a trans-acting factor, we constructed an Spn1(+) mutant th

67 f libraries to provide a prediction of which trans -acting factors binding sites are disrupted/create

68 regulated by a variety of different cis- and trans-acting factors (4, 5).

69 d causes defects in the recycling of several trans-acting factors (hEnp1, hRio2, hLtv1, hDim2/PNO1, a

70 nitiation on Type 1 IRESs also requires IRES trans-acting factors (ITAFs), and several candidates hav

71 Different trans-acting factors (TFs) collaborate and act in concer

72 cis- and trans-acting factors affect gene expression and response

73 This system can be used for studying trans-acting factors and cis-acting sequence elements an

74 The identification of the trans-acting factors and cis-regulatory modules that are

75 sis requires the action of approximately 200 trans-acting factors and the incorporation of 79 ribosom

76 s how cis-acting sequence elements influence trans-acting factors and the local chromatin environment

77 recent strategies aimed at uncovering novel trans-acting factors and their functional role in the NM

78 Unlike most trans-acting factors characterized so far in Chlamydomon

79 RNA cis elements and trans-acting factors contributing to HPV18 alternative R

80 However, RNA cis-regulatory elements and trans-acting factors contributing to HPV18 alternative R

81 These trans-acting factors enable the faithful delivery of sev

82 Recent studies indicate that trans-acting factors establish this stereotypical array.

83 ents, raising the possibility that undefined trans-acting factors governing mRNA stability and transl

84 ment activity requires the binding motif for trans-acting factors Gsh1/Barx2/Brn3.

85 A number of trans-acting factors have also been described to play a

86 Furthermore, we identified trans-acting factors important for tricRNA biogenesis, i

87 Our data reveal distinct roles of cis- and trans-acting factors in the rotational positioning of nu

88 siRNA was used to evaluate the role of trans-acting factors in transcription of TJ genes in res

89 that the assembly specificity is imposed by trans-acting factors in vivo.

90 Regulation of Bril involves trans-acting factors integrating at conserved promoter e

91 ribosomal particles have identified numerous trans-acting factors involved in this process, many prot

92 The structure indicates that the binding of trans-acting factors is required to remodel the tertiary

93 s local activity of super-enhancers and that trans-acting factors modulate DNA methylation profiles w

94 vide the very first analyses of the cis- and trans-acting factors regulating Bril transcription.

95 fied hnRNP A1 (A1) and RPS25 as IRES-binding trans-acting factors required for ER stress-activated ac

96 been well studied, little is known about the trans-acting factors responsible for developmental contr

97 this study, we sought to define the cis- and trans-acting factors responsible for initiation and main

98 To map trans-acting factors responsible, we performed flow sort

99 Trans-acting factors ribosome modulation factor (RMF) an

100 e aim of this study was to discover cis- and trans-acting factors significantly affecting mRNA expres

101 -species complementation, demonstrating that trans-acting factors that are background-dependent contr

102 forward-genetic screens aimed at identifying trans-acting factors that are required for expression of

103 esults advance our knowledge of the cis- and trans-acting factors that are required for transcription

104 fy cis-regulatory elements and corresponding trans-acting factors that contribute to EC identity and

105 an intracellular network of nucleus-encoded, trans-acting factors that control almost all aspects of

106 ack to alterations of cis-acting elements or trans-acting factors that control the establishment, mai

107 To identify trans-acting factors that control VEGF mRNA translation

108 n, including the cis-regulatory elements and trans-acting factors that determine general de novo m(6)

109 We also discuss protein trans-acting factors that have been implicated and the e

110 which indicates the presence of variation in trans-acting factors that influence recombination genome

111 of the PAR and identify controlling cis- and trans-acting factors that make the PAR the hottest segme

112 er, the array of cis-regulatory elements and trans-acting factors that mediate these transcriptional

113 However, trans-acting factors that mediate XCI remain largely unk

114 Over the years, many trans-acting factors that orchestrate transcription by t

115 eukaryotes, these events are facilitated by trans-acting factors that propel ribosome maturation fro

116 abidopsis relies in large part on binding of trans-acting factors to cis-localized DNA sequence motif

117 nd complex process that requires hundreds of trans-acting factors to dynamically build the highly-org

118 throughput system for systematically linking trans-acting factors to endogenous RNA regulatory events

119 ription is orchestrated by multiple cis- and trans-acting factors to ensure appropriate expression of

120 llows measurement of the ability of cis- and trans-acting factors to promote the export and translati

121 re well studied, but how the interactions of trans-acting factors with cis-regulatory modules (CRMs)

122 ry elements, e.g., promoters, enhancers, and trans-acting factors, are essential for the proper contr

123 ssection of both cis-regulatory elements and trans-acting factors, as well as the interpretation of v

124 ass the intricate interplay between cis- and trans-acting factors, chromatin, and the core transcript

125 To gain insight into trans-acting factors, genetic rescue of AdoMetDC RNAi kn

126 on are considered an important complement to trans-acting factors, histone modifications and non-codi

127 Isolation of trans-acting factors, in vitro transcriptional and gel r

128 o well-characterized binding sites for known trans-acting factors, including hepatocyte nuclear facto

129 of RNA are regulated by interactions between trans-acting factors, such as microRNA and RNA-binding p

130 In this study, we identified two p53 IRES trans-acting factors, translational control protein 80 (

131 Sec incorporation requires both cis- and trans-acting factors, which are known to be sufficient f

132 e codes governing splicing and their cognate trans-acting factors, which have illuminated important c

133 that these "seed" nucleosomes--together with trans-acting factors--may facilitate the establishment o

134 ndently controlled by the locally associated trans-acting factors.

135 es are responsive to a multitude of distinct trans-acting factors.

136 lation, mainly because it affects binding of trans-acting factors.

137 lation requires the modulated interaction of trans-acting factors.

138 tial to identify predicted binding sites for trans-acting factors.

139 combination is tightly regulated by cis- and trans-acting factors.

140 g is determined by underlying sequence or by trans-acting factors.

141 mining the accessibility of chromatin DNA to trans-acting factors.

142 l regulation in eukaryotes requires cis- and trans-acting features and factors including RNA secondar

143 ies of a host microRNA, and induction of the trans-acting function of phased secondary small interfer

144 me has allowed evolution of separate cis and trans acting functions, providing selective pressure to

145 Most notable is a trans-acting gamma/delta' hydroxyl group that 99% of oth

146 es nucleosome occupancy maps for discovering trans-acting general regulatory factor (GRF) binding sit

147 panel of human HapMap cell lines to identify trans-acting genes whose expression and/or single-nucleo

148 In the TLE patients, we map the trans-acting genetic control of this proconvulsive modul

149 Identifying these trans-acting genetic modifiers will facilitate the formu

150 ble, implying a role for individual-specific trans-acting genetic modifiers.

151 Trans-acting genetic variants have a substantial, albeit

152 although Arg-349 of sensor II, positioned by trans-acting Glu-286 and Tyr-290, acts as a key residue

153 d to open" movement of Walker A, assisted by trans-acting "Glu switch" Glu-286, facilitates ATP bindi

154 We implemented trans-acting GTP into a computational model for microtub

155 w tightly an incoming subunit will be bound (trans-acting GTP), but most current models do not incorp

156 omplex called Cascade(3,4), which recruits a trans-acting helicase-nuclease, Cas3, for target degrada

157 way leading to target dsDNA degradation by a trans-acting helicase-nuclease.

158 t start codon selection is regulated by many trans-acting initiation factors as well as sequence/stru

159 NA sequencing to identify 4 riboswitches, 13 trans-acting (intergenic), and 22 cis-acting (antisense)

160 tic evidence that the Firre locus produces a trans-acting lncRNA that has physiological roles in hema

161 -function relationship, determining cis- and trans-acting lncRNAs in vivo, and generating new develop

162 Two novel trans-acting loci (15q15.2 and 17q24.3) that were identi

163 genetically divergent strains, we mapped 86 trans-acting loci affecting the expression of ten genes.

164 However, prior work compared trans-acting loci mapped in separate studies, many of wh

165 lity and disruption of MSCI and suggest that trans-acting loci on the X are important for the transcr

166 s and mapped hundreds of underlying cis- and trans-acting loci throughout the genome that regulate hi

167 revealed that this effect was largely due to trans-acting loci, many of which showed evidence of loca

168 additional changes in the IR75b promoter and trans-acting loci.

169 eral muscular dystrophy type 2 (FSHD2) via a trans-acting loss-of-function epigenetic mechanism.

170 of Aire(+) mTEC, our data show how cis- and trans-acting mechanisms are able to control the thymus m

171 by modification of deeply conserved cis- and trans-acting mechanisms of Hox regulation in gnathostome

172 ct viral transcripts use both cis-acting and trans-acting mechanisms to evade degradation.

173 y, as well as the relative roles of cis- and trans-acting mechanisms.

174 he phytohormone auxin, and identify cis- and trans-acting mediators of PIN2 ubiquitylation.

175 owever, modifications of individual cis- and trans-acting modules can be molded by natural selection

176 iple imprinted loci, for which few causative trans-acting mutations have been found.

177 nd how splicing can be disrupted by cis- and trans-acting mutations leading to disease states.

178 racterizes the effects of hundreds of cis or trans-acting mutations on a chromosomal contact.

179 the mode of gene action and the cis- and/or trans-acting nature of each eQTL.

180 s, as well as to infer likely differences in trans-acting ncRNA regulatory networks.

181 While most trans-acting ncRNAs possess well-defined mechanisms that

182 numerous putative regulatory RNAs, including trans-acting non-coding RNAs and anti-sense transcripts.

183 detection of cis-acting (allele-specific) vs trans-acting (non-allele-specific) eQTLs.

184 e is a previously undescribed function for a trans-acting noncoding RNA.

185 ng the recruitment and activity of a host of trans-acting nuclear factors.

186 y complex) to bind foreign DNA and recruit a trans-acting nuclease (i.e., Cas2/3) for target degradat

187 y complex) to bind foreign DNA and recruit a trans-acting nuclease for target degradation.

188 that binds foreign DNA and recruits Cas3, a trans-acting nuclease helicase for target degradation.

189 mbe and S. octosporus, and binding sites for trans-acting nucleosome-excluding proteins functioning i

190 t 4-1BBL is more effective when expressed in trans, acting on adjacent DC.

191 miRNA target mimics and lncRNAs that produce trans-acting or phased small-interfering RNA (tasiRNA/ph

192 lymorphisms within GALNT13 (P < 0.005), four trans-acting (P < 2.1 x 10(-7)) and one cis-acting (P =

193 within their native context and as separate trans-acting peptides, confirmed that the aromatic resid

194 CH protein, TbZFP3, has been identified as a trans-acting post-transcriptional regulator of Procyclin

195 h -2 and -1 PRF and in its requirement for a trans-acting protein factor, the viral replicase subunit

196 lated posttranscriptionally by gene-specific trans-acting protein factors.

197 We also show that an additional trans-acting protein(s) binds specifically to atxA promo

198 ce within the region prevents binding of the trans-acting protein(s), increasing promoter activity 7-

199 plex control of atxA transcription, only one trans-acting protein, the transition state regulator Abr

200 , little is known about the cis-elements and trans-acting proteins involved in regulating AS.

201 e, we found that mutations in genes encoding trans-acting proteins lead to more introns with increase

202 , we identified both cis-acting elements and trans-acting proteins that are required for HBoV1 DNA re

203 etween enhancer cis-acting DNA sequences and trans-acting proteins that recognize these DNA elements

204 tic screening approach in yeast, we identify trans-acting proteins that regulate the accumulation of

205 of HTLV-1 is under the control of two major trans-acting proteins, Tax and Rex.

206 omolecular machinery consisting of dozens of trans-acting proteins.

207 ify several previously unknown modest-effect trans-acting QTL (quantitative trait loci).

208 We observed a significant enrichment of trans-acting rare nonsynonymous secondary variants in pa

209 Putative trans-acting RBPs that recognize prolamine RNA zipcodes

210 -ASM is highly tissue specific; an important trans-acting regulator of genomic imprinting is regulate

211 unological and brain disorders, and ZFP57, a trans-acting regulator of genomic imprinting.

212 ng TALEs, CRISPR/Cas, and sRNAs as synthetic trans-acting regulators in prokaryotes.

213 We report that both cis- and trans-acting regulatory divergence in translation are ab

214 vo model for imprinting and identify a novel trans-acting regulatory factor for imprinted XCI.

215 tive contributions and interplay of cis- and trans-acting regulatory factors to this evolutionary pro

216 Characterizing the trans-acting regulatory proteins that control alternativ

217 ing, through the production of plasmid-coded trans-acting replication inhibitors, and obedience, expr

218 d by a weak cis-acting promoter and putative trans-acting repressor(s) present in A. arenosa and allo

219 iation and somatically acquired mutations in trans-acting repressors contribute to DUX4 re-expression

220 modulated by a novel mechanism, i.e. by the trans-acting RNA binding C-terminal domain of A1.

221 Most known trans-acting RNA effectors consist of fewer than 200 nuc

222 doCbl-binding riboswitch is part of a small, trans-acting RNA, EutX, which additionally contains a du

223 is elements contained within the message and trans-acting RNA-binding proteins (e.g., She2, Puf2).

224 LRV1 lacks cis- or trans-acting RNAi inhibitory activities, suggesting that

225 ddress the question whether fragmentation of trans-acting RNAs is accompanied by the formation of a c

226 messenger in turn targets the CARF domain of trans-acting RNase Csm6, triggering its HEPN domain-base

227 ated by sigB and cshA and plays an important trans-acting role in modulating the transcription and en

228 Firre/FIRRE transgenes, supporting conserved trans-acting roles.

229 ionarily conserved microRNA that targets the Trans-Acting Short Interference RNA3 (TAS3) transcript.

230 eaflet1, is required for the biogenesis of a trans-acting short interfering RNA (ta-siRNA) to negativ

231 h as Argonaute7, a specific component of the trans-acting short interfering RNA3 pathway, an RNA-depe

232 A) biogenesis for their production is termed trans-acting short interfering RNAs (ta-siRNAs).

233 nse and in development via the biogenesis of trans-acting short-interfering RNAs (siRNAs) termed tasi

234 w how evolutionary changes in cis as well as trans acting signals have played a fundamental role in d

235 R828 in Arabidopsis triggers the cleavage of Trans-Acting SiRNA Gene 4 (TAS4) transcripts and product

236 Finally, conserved trans-acting siRNA pathways were characterized and confi

237 y spaced lateral organs, suggesting that the trans-acting siRNA3 (TAS3) pathway negatively regulates

238 is targeted by miR828 and miR858, generating trans-acting siRNAs (ta-siRNAs) in the TAS4 family.

239 22 novel miRNAs and 6 genomic loci producing trans-acting siRNAs (ta-siRNAs) including TAS3a to TAS3e

240 ssed highly abundant but less conserved TAS3 trans-acting siRNAs (tasiRNAs) in addition to tasiR-ARFs

241 Trans-acting siRNAs (tasiRNAs) negatively regulate targe

242 MicroRNAs (miRNAs), trans-acting siRNAs (tasiRNAs), heterochromatic siRNAs (

243 licing is required for biogenesis of phased, trans-acting siRNAs (tasiRNAs), whose cleaved precursor

244 a limited number of RNAs are processed into trans-acting siRNAs (tasiRNAs).

245 or transgene silencing and the production of trans-acting siRNAs.

246 captures microRNA390, contributing to reduce trans acting small interference Auxin Response Factor pr

247 onstrated that a short variant of the lncRNA Trans-acting small interference RNA3 (TAS3) increased it

248 3 by ARGONAUTE7 results in the production of trans-acting small interference RNAs, which target mRNAs

249 uced accumulation of miR390, an initiator of trans-acting small interfering RNA (ta-siRNA) formation,

250 the shared repression of ARF3 by the AS and trans-acting small interfering RNA (ta-siRNA) pathways i

251 by promoting the biogenesis of TAS3-derived trans-acting small interfering RNA (ta-siRNA), which rep

252 wo TAS gene families with similar but unique trans-acting small interfering RNA (tasiRNA) biogenesis

253 Our results demonstrate that the trans-acting small interfering RNA class of small RNAs a

254 re, we demonstrate that the microRNA (miRNA)-trans-acting small interfering RNA gene (TAS)-pentatrico

255 thway that intersects and interacts with the trans-acting small interfering RNA pathway.

256 -like protein required for the biogenesis of trans-acting small interfering RNA, which regulates the

257 Artificial microRNAs (amiRNAs) and synthetic trans-acting small interfering RNAs (syn-tasiRNAs) are u

258 of artificial miRNAs (amiRNAs) and synthetic trans-acting small interfering RNAs (syn-tasiRNAs) for e

259 Among them, microRNAs (miRNAs) and trans-acting small interfering RNAs (ta-siRNAs) mainly i

260 Trans-acting small interfering RNAs (tasiRNAs) are a maj

261 atens miR156 also influences accumulation of trans-acting small interfering RNAs (tasiRNAs) dependent

262 Plant microRNAs (miRNAs) and trans-acting small interfering RNAs (tasiRNAs) play impo

263 sses of sRNAs such as microRNAs (miRNAs) and trans-acting small interfering RNAs have been shown to b

264 g RNAs (phasiRNAs), originally designated as trans-acting small interfering RNAs or tasiRNAs.

265 own function) is controlled by both CER7 and trans-acting small interfering RNAs.

266 imary function is to promote pairing between trans-acting small non-coding RNAs (sRNAs) and their tar

267 tRNA fragmentation can coordinately generate trans-acting small RNAs and functionally deplete a tRNA.

268 d cognate target messenger RNAs and specific trans-acting small RNAs, such as the posttranscriptional

269 iate RNase-dependent decay, similar to other trans-acting small RNAs.

270 NDOR, a method that represents both cis- and trans-acting SNPs and the genes with which they are asso

271 y one cis-acting SNP is modulated by several trans-acting SNPs.

272 at KDM4B can function as a signal responsive trans-acting splicing factor and scaffold that recruits

273 reds of transcripts, which can sequester the trans-acting splicing factor PTBP2.

274 ilencers that regulate exon 13 inclusion via trans-acting splicing factors like PTBP1 and TIAL1.

275 egulation by viral RNA cis elements and host trans-acting splicing factors.

276 ne is regulated by both intronic repeats and trans-acting splicing factors.

277 Our data identified PcrZ as a trans acting sRNA with a direct regulatory function in f

278 NrrF, a trans-acting sRNA in Neisseria meningitidis and Neisseri

279 We show that Bacillus subtilis RoxS, a major trans-acting sRNA shared with Staphylococus aureus, prev

280 ain and interacts with a newly characterized trans-acting sRNA, RocR.

281 Independent expression of four novel trans-acting sRNAs (Rc_sR31, Rc_sR33, Rc_sR35, and Rc_sR

282 Q/FinO domain-containing proteins can assist trans-acting sRNAs and that this class of RNA chaperones

283 putative colonization factor PrpB by the two trans-acting sRNAs RcoF1/2.

284 The goal of this study is to identify trans-acting sRNAs that can be substrates of RNase III.

285 One class of sRNAs, trans-acting sRNAs, are the most abundant sRNAs transcri

286 -term ribosome deficits through compensatory trans-acting suppressors, cells are penalized in the lon

287 estion is whether proteins might function as trans-acting switches to turn frameshifting on or off in

288 dules that are likely involved in recruiting trans-acting targeting factors.

289 terminator read-through assay, we identified trans-acting Terminator Override (TOV) genes that operat

290 moter deletion/substitutions, mutants in the trans-acting transcription factors and their upstream pr

291 which remain silent even in the presence of trans-acting transcriptional activators.

292 us demonstrate that our approach can uncover trans-acting transcriptional control circuits that affec

293 nd proteomic studies, we show that FthB is a trans-acting transfer RNA (tRNA) editing protein, which

294 While trans-acting tRNA editing proteins have been found to co

295 ctivity and upon heptamerization, packing of trans-acting Tyr(290) against cis-acting Arg(349) compel

296 ple, in response to a virus-like stimulus, a trans-acting variant responds as an activator of the ant

297 additive inheritance, while those linked to trans-acting variants are most often dominantly inherite

298 This suggests the existence of trans-acting variants in modifier genes.

299 ependent RNA polymerase (L protein), the two trans-acting viral factors required for both virus RNA r

300 ge-scale RNA interference screen to identify trans-acting XCI factors (XCIFs) that comprise regulator