ライフサイエンスコーパス: transacetylase

1 phenicol acetyltransferase and dihydrolipoyl transacetylase.

2 ependent acetylation catalyzed by homoserine transacetylase.

3 solubilized and purified this PAF-dependent transacetylase 13,700-fold from rat kidney membranes (mi

4 ustained the stimulation of PAF:acyllyso-GPC transacetylase activity by ATP.

5 stent with the notion that ATP regulates the transacetylase activity by reversible activation and ina

6 Reduced PAF:acyllyso-GPC transacetylase activity can be restored by incubating th

7 atase reduces the increased PAF:acyllyso-GPC transacetylase activity from the homogenates of ATP-acti

8 PAF transacetylase activity is widely distributed among seve

9 membranes) based on the PAF:lysoplasmalogen transacetylase activity.

10 ed as PAF:lysoplasmalogen (lysophospholipid) transacetylase and PAF:sphingosine transacetylase, respe

11 C2-ceramide is produced via PAF:sphingosine transacetylase, and physiological levels of C2-ceramide

12 C) block the activation of PAF:acyllyso-GPC transacetylase by ATP.

13 present study, we demonstrate that a similar transacetylase can transfer the acetate group from PAF t

14 ramphenicol acetyltransferase, dihydrolipoyl transacetylase, carnitine acetyltransferase, and VibH, a

15 cetyl-CoA only occurred upon addition of the transacetylase-catalyzing (lipoyl domain-free) inner cor

16 yl-bearing domains (L2) of the dihydrolipoyl transacetylase component (E2) of PDC.

17 s a stronger response to the addition of the transacetylase component along with a better binding to

18 ffect is due largely to the inability of the transacetylase component of PDC to promote the phosphory

19 acetylation of the E. coli dihydrolipoamide transacetylase component, whereas crystallographic resul

20 the lipoyl-bearing domain(s) provided by the transacetylase component.

21 ugh the inner lipoyl-bearing domains (L2) of transacetylase component.

22 omethylation of its subunit dihydrolipoamide transacetylase (DLAT) at lysine 596.

23 ation induced by mitochondrial dihydrolipoyl transacetylase (DLAT), independent of the pyruvate dehyd

24 s, we identify upregulation of dihydrolipoyl transacetylase (DLAT), the E2-subunit of pyruvate dehydr

25 internal E3-binding domains of dihydrolipoyl transacetylase (E2) and E3BP.

26 e dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase c

27 oyl-bearing domain (L2) of the dihydrolipoyl transacetylase (E2).

28 inner lipoyl domains (L2) from the 60-meric transacetylase (E2p) core of PDC, with concomitant stimu

29 pyruvate dehydrogenase (E1p), dihydrolipoyl transacetylase (E2p), and dihydrolipoamide dehydrogenase

30 We have cloned homoserine transacetylase from H. influenzae and present the first

31 mino acids which has significant homology to transacetylases from many bacteria.

32 A comparison of homoserine transacetylases from other bacterial and fungal species

33 frame orthologous to bacterial cysE (serine transacetylase) genes.

34 PAF:sphingosine transacetylase has a narrow substrate specificity and st

35 e transsuccinylase (HTS, metA) or homoserine transacetylase (HTA; met2) for the biosynthesis of methi

36 reviously identified a novel CoA-independent transacetylase in the membrane fraction of HL-60 cells t

37 which is quite different from its homologous transacetylase in this region.

38 These results suggest that PAF-dependent transacetylase is an enzyme that modifies the cellular f

39 er lipoyl-bearing domain of dihydrolipoamide transacetylase (L2) determined with or without bound ade

40 The homoserine transacetylase MetX converts L-homoserine to O-acetyl-L-

41 Overexpression of histone transacetylases p300, CBP and PCAF stimulated transcript

42 r data show that both acetyltransferases and transacetylase participate in and contribute to the bios

43 nd that the CoA-independent PAF:acyllyso-GPC transacetylase recently identified by us is concurrently

44 pholipid) transacetylase and PAF:sphingosine transacetylase, respectively.

45 e movement of PDHK2 along the surface of the transacetylase scaffold.

46 the full-length 10-deacetylbaccatin III-10-O-transacetylase sequence was obtained.

47 ingosine, the CoA-independent, PAF-dependent transacetylase serves as a modifier of PAF, and sphingos

48 Chloramphenicol transacetylase transcriptional fusions indicate that a r

49 the acetyltransferases precedes that of the transacetylase with peak activation occurring at 1-2 min