ライフサイエンスコーパス: transactivation

1 IE is essential for mediating AF-1-dependent transactivation.

2 age of infection and abrogated IE62-mediated transactivation.

3 suggesting that a novel mechanism exists for transactivation.

4 KLF15 occupied ICP0 sequences important for transactivation.

5 egradation in endolysosomes and restrict LTR transactivation.

6 ptake and its consequences for cellular gene transactivation.

7 osomes and restricted Tat-mediated HIV-1 LTR transactivation.

8 NF-kappaB transcriptional activity and CCL2 transactivation.

9 nstrated in Fxr(-/-) mice, and involved EGFR transactivation.

10 enhancer complex, are predicted to drive INS transactivation.

11 endently of epidermal growth factor receptor transactivation.

12 ear translocation and TCF/LEF-dependent gene transactivation.

13 nces the ELL2-SEC formation for robust HIV-1 transactivation.

14 leads to MR1- and cytokine-dependent NK cell transactivation.

15 M attenuated Tat endolysosome escape and LTR transactivation.

16 ely amplifying its functional effect on gene transactivation.

17 y for agonists, producing inhibition of gene transactivation.

18 iption start site that is required for KLF16 transactivation.

19 hat mutant HTT represses PPAR-delta-mediated transactivation.

20 gent effects on TGF-beta signaling and IRF-1 transactivation.

21 3(V172F) complex that inhibits p53-dependent transactivation.

22 , and interferon regulatory factor 1 (IRF-1) transactivation.

23 n Tat endolysosome escape and subsequent LTR transactivation.

24 rease in the ability of p107 to inhibit E2F2 transactivation.

25 mic translocation, inhibiting FoxO1-mediated transactivation.

26 ect repression in vitro, but does not affect transactivation.

27 n Tat endolysosome escape and subsequent LTR transactivation.

28 Elongation Complex (SEC) essential for HIV-1 transactivation.

29 ations 10-fold lower than those required for transactivation.

30 ) attenuated Tat endolysosome escape and LTR transactivation.

31 normoxia is a prerequisite for HIF-mediated transactivation.

32 ulti-parametric data was shaped primarily by transactivation.

33 fate and for their impact on CYP3A4 promoter transactivation.

34 says: MCF-7 cell proliferation and VM7Luc4E2 transactivation.

35 stress-induced mitophagy through NFE2L2/NRF2 transactivation.

36 he major effector of RAGE activation was its transactivation.

37 led perturbation of intrinsic, PBX-dependent transactivation ability and altered nuclear translocatio

38 Inhibition of RORalpha and RORgamma transactivation activities in a Tet-on CHO cell reporter

39 with a unique combination of phosphatase and transactivation activities.

40 XIT had significant dose-dependent PPARgamma transactivation activities.

41 phorylation also enhanced the SUMO-dependent transactivation activity and auto-repression activity of

42 bolishes its interaction with MtLUG, and its transactivation activity and biological function.

43 er, AmphiSOXE is less efficient than SOX9 in transactivation activity and in the ability to preferent

44 the promoter region of ORF50, increasing its transactivation activity and KSHV spontaneous lytic gene

45 Transactivation activity assays performed in Arabidopsis

46 However, IFN-gamma abrogated IE62's transactivation activity by 16% in MeWo cells, indicatin

47 er reporter plasmid, IFN-gamma abrogated the transactivation activity of IE62 by 95%, 97%, and 89% in

48 HepG2 cells were used to assess the transactivation activity of mERbeta isoforms with EDCs a

49 The transactivation activity of OsNIN-like3 needs to be furt

50 The transactivation activity of OsNIN-like3 was not possible

51 nhibitors of MCFA-CoA synthases increase the transactivation activity of the ARM repeat protein beta-

52 K-Rta transactivation activity requires a protein degradation

53 bility or cellular localization, whereas its transactivation activity was hindered.

54 sically interacts with GCM1 and inhibits its transactivation activity, suggesting that DLX3 and GCM1

55 more, HI-TOPK-032 decreased SSL-induced AP-1 transactivation activity.

56 tant protein demonstrated a 75% reduction in transactivation activity.

57 and enhanced Tat-mediated HIV-1 LTR promoter transactivation, along with stabilization of Tat protein

58 Increased PPAR-delta transactivation ameliorated mitochondrial dysfunction an

59 s I VNTR probe were performed to examine the transactivation and binding activities of WT, mutant, an

60 eased in the presence of androgens, enabling transactivation and causing the receptor to become aggre

61 rylation by PKA and significantly reduced AR transactivation and cellular proliferation.

62 cis but also in trans Multiallelic promoter transactivation and ChIP analyses demonstrated that inte

63 investigated regulation of the EDNRB gene in transactivation and chromatin immunoprecipitation assays

64 f BP-3 and PP on estrogen receptor-dependent transactivation and DNA damage at concentrations relevan

65 and investigated the regulation of ERN1 via transactivation and DNA-protein interaction assays.

66 T-DNA insertion mutant using flow cytometry, transactivation and electrophoretic mobility shift assay

67 monolayers that was dependent on matriptase transactivation and PAR2 signaling.

68 potential mechanism of the initiation of AR transactivation and potential targets for developing and

69 trazole at reducing aromatization-induced ER transactivation and proliferation.

70 ited higher maximal aromatization-induced ER transactivation and reduced anastrazole sensitivity, a d

71 vo approaches, we found significantly higher transactivation and replication of HIV-1-CRF02_AG (preva

72 ed Tat.AG- and HIV-1-CRF02_AG-mediated viral transactivation and replication, but not Tat.B- or HIV-1

73 Together, neddylation pathway promotes CCL2 transactivation and TAMs infiltration in lung cancer to

74 to GC-induced activation of both the direct transactivation and the direct transrepression functions

75 regarding the pursuant feedback between p53 transactivation and thiamine homeostasis.

76 3 at serine 259 (Ser259), which enhanced the transactivation and transcriptional activity of NFAT3.

77 lysis suggests that ligand-specific receptor transactivation and utilization of regional-specific est

78 ces were essential for the ERalpha-dependent transactivation and were differentially recognized by E2

79 o display reduced MAPK activation, NF-kappaB transactivation, and delayed NF-kappaB nuclear transloca

80 lationship of QSAR predictions of binding to transactivation- and pathway-based assays, as well as to

81 nt HIV-1 long-terminal repeat (LTR) promoter transactivation as well as HIV-1 virion production.

82 chemicals were readily identified in the TR transactivation assay, but only a single novel, direct a

83 We also used a transcellular Tat transactivation assay, where we expressed Tat proteins o

84 antagonist activity in the estrogen receptor-transactivation assay.

85 ode nuclear protein extracts, and protoplast transactivation assays demonstrated that ShMYB78 activat

86 ts with IP and performed complementation and transactivation assays in NEMO-deficient cells.

87 Transactivation assays indicated that CsMYBF1 activated

88 By transactivation assays, all EBF3 mutants showed signific

89 tivity was assessed with a suite of in vitro transactivation assays, and Sprague-Dawley rats were use

90 In luciferase transactivation assays, p.Thr454Met had about one-third

91 COREXIT, as a probable obesogen by PPARgamma transactivation assays, PPAR-driven luciferase induction

92 Using transient transactivation assays, we show that the StSP6A tuberisa

93 er, non-TR-specific mechanisms common to the transactivation assays.

94 risk of insertional mutagenesis and oncogene transactivation associated with the first generation of

95 EGLN1, causing changes in downstream target transactivation, associated with a blunted hypoxic respo

96 l p53-promoter element interactions and gene transactivation-associated events, yet dispensable for 5

97 cupied ICP0 promoter sequences important for transactivation at 2 and 4 h after infection; however, b

98 stant cell line induced p53 and restored p21 transactivation at 37 degrees C, as did cisplatin-induce

99 potencies determined by use of the H4IIE-luc transactivation bioassay.

100 Vimentin is important for Notch transactivation by ECs and vimentin knockout mice (VimKO

101 in colocalization of these molecules and RTK transactivation by GPCRs and CAMs, giving rise to extrac

102 roteasomal degradation, CDK7 is dependent on transactivation by MITF or c-MYC to maintain a steady st

103 HIT immune complexes through FcgammaRIIA and transactivation by monocyte-derived thrombin markedly in

104 gulatory elements and was required for their transactivation by NKX2-1 in MGE-like progenitors.

105 tral role in androgen receptor (AR)-mediated transactivation by phosphorylating both RNA polymerase 2

106 linked ubiquitination of nuclear p53 and its transactivation by recruiting p300 for p53 acetylation.

107 Transactivation by Tat-B was significantly reduced by R5

108 These data position RAGE transactivation by the AT1 receptor as a target for vasc

109 as DUOX1 and Src play a primary role in EGFR transactivation by wound-derived signals such as ATP, di

110 ellular localization, affinity for HSP90 and transactivation capability.

111 oteins and analyzed them for DNA binding and transactivation capability.

112 Two missense variants showed reduced transactivation capacity in our assays, whereas one vari

113 ter to the luciferase gene, we show that the transactivation capacity of the promoter is significantl

114 esponse elements significantly decreases the transactivation capacity of the promoter.

115 ars a superior readout supporting pursuit of transactivation-centric experimental designs for high-th

116 Targeting the active Notch transactivation complex by using the cell-permeable, hyd

117 TAK1, predominantly via PPARalpha N-terminal transactivation domain (AF-1) thereby masking the TAK1 k

118 hypoxic activation of HIF-1alpha C-terminal transactivation domain (C-TAD), but not HIF-1alpha-N-ter

119 if3a blocked hyperosmotic increase of TonEBP-Transactivation Domain (TAD) activity, overall the knock

120 EZH2 harbors a hidden, partially disordered transactivation domain (TAD) capable of interacting with

121 The C-terminal transactivation domain (TAD) of BMAL1 (brain and muscle

122 ding of MDM2 to the intrinsically disordered transactivation domain (TAD) of p53.

123 ivators on an alpha-helix located within the transactivation domain (TAD) of the BMAL1 C terminus.

124 ulated by interactions of BMAL1's C-terminal transactivation domain (TAD) with the KIX domain of CBP/

125 Loss of the RelB transactivation domain alters NF-kappaB-dependent transc

126 n of residues S650 and S975 weakens the E2F4 transactivation domain binding.

127 ct sites on CLOCK and BMAL1 to sequester the transactivation domain from coactivators.

128 EWS-FLI1 harbors a strong transactivation domain from EWSR1 and the DNA-binding ET

129 the AD2 interaction motif of the N-terminal transactivation domain functions as a phosphorylation-de

130 eptides that display key residues of the p53 transactivation domain have emerged as bona fide clinica

131 In contrast, the transactivation domain in ELK1 was only required for act

132 partite transactivation mechanism, whereby a transactivation domain in the middle of the proteins (TA

133 l for mammary gland development and contains transactivation domain isoforms, which have tumor-suppre

134 A key prediction is that the Tat transactivation domain makes modest contacts with the TA

135 the folding of the intrinsically disordered transactivation domain of c-Myb (c-Myb) upon binding its

136 in-mutagenesis experiments revealed that the transactivation domain of c-Myb was necessary for restra

137 ajor satellite transcription, and the strong transactivation domain of NANOG is required for this org

138 -dependent) phosphorylation of Ser536 in the transactivation domain of NF-kappaB p65.

139 705)-STAT3 and indicated that the C-terminal transactivation domain of RTA was required for enhancing

140 induced phosphorylation at serine 754 in the transactivation domain of STAT3.

141 K directly interacts with the amino terminus transactivation domain of the AR to stabilise it thereby

142 and unambiguous assignment on the disordered transactivation domain of the tumor suppressor p53, alph

143 show that SHP physically interacts with the transactivation domain of XBP1s, thereby inhibiting the

144 edicted to result in the loss of part of the transactivation domain of YAP1, and sequencing of cDNA f

145 mission EM, we noted that the p53 N-terminal transactivation domain significantly reduces aggregation

146 ough its intrinsically disordered C-terminal transactivation domain with the TAZ1 (also known as CH1)

147 ontain a PST (Proline-Serine-Threonine)-rich transactivation domain, a threonine phosphatase motif (T

148 o1, an activity dependent on M303 in c-Myb's transactivation domain, and likely the recruitment of co

149 h required expression of both the N-terminal transactivation domain, and the C-terminal ligand bindin

150 on timing regulatory factor 1 (RIF1) and Pax transactivation domain-interacting protein (PTIP), in th

151 RCA1 C-terminal) domain-containing PTIP (Pax transactivation domain-interacting protein) chromatin re

152 oted by the BRCT domain-containing PTIP (Pax transactivation domain-interacting protein).

153 nt on a key C-terminal domain located in its transactivation domain.

154 e Pyk2 phosphorylates tyrosine 131 in the E2 transactivation domain.

155 for TAZ1 binding through its own disordered transactivation domain.

156 some processing but independent of NF-kappaB transactivation domain.

157 esidues regulates p107 affinity for the E2F4 transactivation domain.

158 ine-rich motif, a proline-rich domain, and a transactivation domain.

159 the oncogenic chimera E2A-PBX1 contain three transactivation domains (ADs), with AD1 and AD2 having r

160 en-activated protein kinases (MAPK) in their transactivation domains (TAD) at so-called phosphoswitch

161 The p53 N terminus (NT) contains two transactivation domains (TAD1 and TAD2), a proline-rich

162 ntrinsically disordered transcription factor transactivation domains (TADs) function through structur

163 The HIF-1alpha and CITED2 transactivation domains bind to TAZ1 through helical mot

164 -Cas9 proteins (dCas9) fused to heterologous transactivation domains can act as a potent guide RNA se

165 scaffolds for the interaction of disordered transactivation domains from a wide variety of partners,

166 ERGalt retains the DNA-binding and transactivation domains of ERG, but it inhibits wild-typ

167 mpact of the mutation on the DNA-binding and transactivation domains of FOXN1.

168 xpressing dCas9 with the VPR transcriptional transactivation domains under the control of the Myh (my

169 active dead (d)Cas9 fused to transcriptional transactivation domains were developed for directing spe

170 he combined properties of amino terminal and transactivation domains.

171 E2 has the greatest transactivation effect on expression of SRSF3.

172 ations based on their effects on target-gene transactivation, effects of cancer mutations on tumor fo

173 vely, our study identifies a basic lipogenic transactivation event with broad relevance to human vira

174 important mediators of host-ligand regulated transactivation events in schistosomes, and represent po

175 require the primary late-gene-specific viral transactivation factor, suggesting that cryptic transcri

176 Corticosteroid-mediated transactivation (FK506-binding protein 5 induction by FL

177 ocorticoid receptor alpha and corticosteroid transactivation (FK506-binding protein 5) and transrepre

178 es loss of YAP1, implicating transcriptional transactivation function in mediating force-enhanced cel

179 tanding of mechanisms underlying the central transactivation function of SOXE proteins, these finding

180 dent transcription regulator, containing two transactivation functional domains, AF-1 and AF-2.

181 TSPY and TSPX exert opposing effects on the transactivation functions of AR and AR-Vs important for

182 rus activation is not mediated by viral gene transactivation, given that these mutations do not incre

183 its VZV replication as well as IE62-mediated transactivation in a cell line-dependent manner.

184 ental mechanism underlying CHD4-mediated HIF transactivation in breast tumors.

185 Thus, disruption of GATA4-mediated transactivation in HCC suppresses hepatocyte epithelial

186 Mechanistically, ZL0580 inhibits Tat transactivation in microglia by disrupting binding of Ta

187 Sixteen of these genes were screened for transactivation in response to diverse cellular insults.

188 p53 cis-elements were required for efficient transactivation in response to temozolomide.

189 omponents of COREXIT contribute to PPARgamma transactivation in the CWAF.

190 sosome pH, as well as Tat-mediated HIV-1 LTR transactivation in U87MG cells stably integrated with HI

191 x in vitro, fully antagonized PU.1-dependent transactivation in vivo.

192 Mithramycin is a FXR expression and FXR transactivation inhibitor that inhibits bile flow and po

193 state cancer, but the mechanisms by which AR transactivation is dysregulated during cancer progressio

194 Transactivation is mediated by direct binding of TSARs t

195 ent LBD stabilization assays, and cell-based transactivation measurements delineate structure-activit

196 uncover that the proteins share a bipartite transactivation mechanism, whereby a transactivation dom

197 -binding pocket and overlapping with minimal transactivation motifs (9-aa-TAD) described in many tran

198 We show that allele-specific SbMATE transactivation occurs and is caused by factors located

199 sion of phosphodiesterase 4D (PDE4D) through transactivation of a G protein-coupled receptor kinase 2

200 ed GR interaction and dexamethasone-mediated transactivation of a GRE reporter while still maintainin

201 though we demonstrate that Cav1 regulates GR transactivation of anti-inflammatory genes, this does no

202 n factor subunit (cJUN) and potentiating the transactivation of AP-1 targets such as osteocalcin (Bgl

203 ience may be explained by estradiol-mediated transactivation of beta1-integrins and tropomyosin recep

204 medaka ERs (mERs) are capable of initiating transactivation of both VTG I and II, with ERbeta2 exhib

205 In support of this result, RNF126 promotes transactivation of BRCA1 promoter by directly binding to

206 Despite defective transactivation of canonical target genes, SD-Foxo1 prom

207 that neddylation inactivation suppresses the transactivation of chemotactic cytokine ligand 2 (CCL2).

208 p IX of AP2/ERF family, might involve in the transactivation of defense-related genes.

209 SAR1 and TSAR2 exhibit different patterns of transactivation of downstream triterpene saponin biosynt

210 or 1 (GPER/GPR30) mediates these effects via transactivation of EGFR and subsequent MAPK activation.

211 so the shedding protease responsible for the transactivation of EGFR by LPA in ovarian cancer cells.

212 which further facilitated the c-Src-mediated transactivation of epidermal growth factor receptor.

213 c-MYC implicated in general transcription by transactivation of far upstream binding protein 2 (FUBP2

214 CR signal outputs to selectively repress the transactivation of Foxp3 and limit the inopportune induc

215 actors is capable of activating EGR mediated transactivation of genes involved in angiogenesis and ce

216 rmine RUNX2 availability in OA cartilage for transactivation of genes such as MMP13.

217 Reciprocally, transactivation of GMPR is required for MITF-dependent s

218 the pERRE3tk-LUC plasmid, which demonstrated transactivation of GOT.

219 nd UVR-induced nucleotide excision repair by transactivation of GTF2H1 as a core element of TFIIH.

220 IPs and their putative heterodimers-mediated transactivation of GUS reporter gene.

221 II from promoter-proximal pausing and in the transactivation of HIV-1 transcription.

222 iated histone modifications and, ultimately, transactivation of inflammatory genes in mouse macrophag

223 alf-life [t (1/2)], ~10 h) but inhibited SP1 transactivation of its core promoter, localized to bp -1

224 ion were attenuated when RAGE was deleted or transactivation of its cytosolic tail was inhibited.

225 ncreases p53 protein levels and enhances the transactivation of its target genes in response to stres

226 deacetylase (HDAC), resulting in epigenetic transactivation of KSHV lytic genes.

227 ed cell migration by directly inhibiting the transactivation of LAMC2.

228 that low, but not high, doses promoted AICD transactivation of microtubule associated serine/threoni

229 Mechanistically, transactivation of miR-802 by aromatic hydrocarbon recep

230 inhibits migration and invasion by blocking transactivation of MMPs driven by beta-catenin, whereas

231 Y1 also suppresses the transcription and the transactivation of myocardin (MYOCD), a master regulator

232 ates NF-kappaB p65 nuclear translocation and transactivation of NF-kappaB to promote the extracellula

233 ction of lincRNA-Tnfaip3 is required for the transactivation of NF-kappaB-regulated inflammatory gene

234 ion of the KEAP1-NRF2 pathway results in the transactivation of NRF2 target genes, consequently induc

235 leukemia, because the viral enhancer induced transactivation of oncogenes.

236 hrough "paradoxical MEK/ERK signaling" where transactivation of one protomer occurs as a result of dr

237 We also find evidence for functional transactivation of PDGFRA by EGFR and EGF-induced recept

238 nal/posttranslational feedback loop in which transactivation of Per (period) and Cry (cryptochrome) g

239 first structure-based mechanism for the auto-transactivation of RAF and could be generally applicable

240 The transactivation of RAF dimers and ERK signaling promotes

241 eptide S391A-RAGE362-404 was able to inhibit transactivation of RAGE and attenuate Ang II-dependent i

242 This binding induces the transactivation of Rheb.

243 aining non-activatable rhodopsin, ruling out transactivation of rhodopsin by opsin.

244 2, EGR 3 and EGR 4 which are involved in the transactivation of several genes.

245 vation triggers the progressive E2f-mediated transactivation of Socs3, a potent inhibitor of Jak2 sig

246 mmetry, couples SLO BK potassium channels to transactivation of sox-2 expression for the induction of

247 w NSY-7 couples SLO BK potassium channels to transactivation of sox-2 expression for the induction of

248 However, BP-3 and PP had limited transactivation of target genes at 1 muM and 5 muM conce

249 e assays indicate six risk alleles increased transactivation of the ADHD8 promoter.

250 n, this was confirmed, and it was shown that transactivation of the AID gene (AICDA) is associated wi

251 T/NAP domain, and exacerbate and repress the transactivation of the AR/AR-V7 target genes in ligand d

252 vely, these studies suggest that cooperative transactivation of the bICP0 E promoter by two pioneer t

253 t significantly reduce GR- and KLF4-mediated transactivation of the bICP0 E promoter, suggesting that

254 kt3, impaired GR- and dexamethasone-mediated transactivation of the BoHV-1 immediate early transcript

255 not Akt3, significantly reduced GR-mediated transactivation of the BoHV-1 immediate early transcript

256 eceptor by angiotensin II (Ang II) triggered transactivation of the cytosolic tail of RAGE and NF-kap

257 ion of TNF-alpha by LPA also depended on the transactivation of the epidermal growth factor receptor

258 to the initiation of female puberty through transactivation of the GnRH promoter.

259 ssential role in mediating PPARdelta-induced transactivation of the LPCAT3 gene.

260 , yet distinct from, the ubiquitin-dependent transactivation of the oncoprotein Myc by other E3s.

261 ssion suggesting an important role of p53 in transactivation of these genes.

262 1-E2F4-dependent and GOF mutant p53-mediated transactivation of UBE2C is NF-Y-dependent.

263 dherin and beta-catenin/APC PPIs, suppressed transactivation of Wnt/beta-catenin signaling in dose-de

264 MOylation of p53, inhibition of p53-mediated transactivation or efficiently transforming primary rode

265 The importance of this transactivation pathway was demonstrated by our finding

266 es directly with the experimentally measured transactivation potential of a large set of mutagenized

267 We show the global viral transactivation potential of all four RTA isoforms and d

268 A1 regulatory plexus significantly alter the transactivation potential of cis-regulatory elements by

269 er Assays reveal that few SNVs can alter the transactivation potential of individual cis-regulatory e

270 BPD), which is essential for the gradational transactivation property of eSTR and FOXA3 may also be i

271 The HIV-1 transactivation protein (Tat) binds the HIV mRNA transac

272 n the DOG1 promoter affects bZIP67-dependent transactivation, providing a mechanism to explain ecotyp

273 Here, using NMR and the HIV-1 transactivation response (TAR) element as a model system

274 ow peptides and proteins recognize the HIV-1 transactivation response (TAR) element, a 59-nucleotide-

275 ic ALS patients feature abnormalities in the transactivation response DNA-binding protein of 43 kDa (

276 Transactivation response element (TAR) DNA-binding prote

277 the conformational equilibrium of the HIV-1 transactivation response element (TAR) RNA, such that th

278 In bulge-stem-loop constructs of HIV-1 transactivation response element (TAR) RNA, we achieved

279 higher phosphorylated-tau levels compared to transactivation response element DNA-binding protein 43

280 Transactivation response element RNA-binding protein (TR

281 we reported an ATP-independent diffusion of transactivation response RNA binding protein (TRBP) on d

282 sactivation protein (Tat) binds the HIV mRNA transactivation responsive element (TAR), regulating tra

283 he HIV-1 transactivator protein Tat and TAR (transactivation responsive region) RNA, plays a critical

284 on studies using siRNAs confirmed a positive transactivation role of c-Jun and ATF-2 but unexpectedly

285 IFCAR impairs the hypoxia-induced HIF-1alpha transactivation, sphere-forming ability, metabolic shift

286 Reduced Jagged1-Notch transactivation strength disrupts lateral signal inducti

287 henotype in 4 unrelated families by in vitro transactivation studies in which pathogenic variants res

288 Transactivation studies with a reporter gene assay revea

289 N-terminal domain of MDM2 and the N-terminal transactivation (TA) domain of p53 (residues 15-29).

290 domains necessary for GR- and KLF4-mediated transactivation that are distinct from those for GR and

291 imary function of the PST and TPM domains is transactivation that can be largely substituted by the h

292 , induced IL-10RA mRNA, IL-10RA protein, and transactivation through activated Stat3 and HDAC inhibit

293 that inhibition of this complex reduces MIEP transactivation, thus inhibiting viral reactivation.

294 nown HBZ-modulated pathways: NF-kappaB (p65) transactivation, transforming growth factor beta (TGF-be

295 nt despite preservation of GCS-mediated gene transactivation under hypoxia.

296 light of its role in glucocorticoid receptor transactivation, we investigated whether SKA2 DNA methyl

297 effects of ML-SA1 on Tat-mediated HIV-1 LTR transactivation were blocked using pharmacological inhib

298 O, PLTP, PLXNB3, and LCN15) showed defective transactivation when treated with Nutlin-3a.

299 by vamorolone selectively reduces GR-driven transactivation while leaving transrepression intact.

300 a derivative of retinoid) suppressed the TR4 transactivation with increased DTX chemo-sensitivity.