ライフサイエンスコーパス: transcript level

1 regulation of nuclear gene expression at the transcript level.

2 d with matrix remodelling were observed at a transcript level.

3 d false discovery rate, in particular at the transcript level.

4 rboxykinase 2 ( Pck2) mRNA and increased its transcript level.

5 neurodegenerative diseases, primarily at the transcript level.

6 d most commonly in ecDNA, thereby increasing transcript level.

7 CSF3, LOC100152038, and LOC100736831 at the transcript level.

8 proach for assessing paralog activity at the transcript level.

9 ng mechanism in grasses at physiological and transcript levels.

10 s to the promoter of BBX31 and regulates its transcript levels.

11 y gene derepression at nascent and processed transcript levels.

12 A expression and genotype, phenotype or UPF1 transcript levels.

13 These responses include changes in transcript levels.

14 els of H2A.Z in the gene body correlate with transcript levels.

15 Small interfering RNA was used to decrease transcript levels.

16 interact with the MOR promoter and modulate transcript levels.

17 nts such as various epigenetic marks or mRNA transcript levels.

18 1282X cells despite the presence of adequate transcript levels.

19 largely regulated at the translation but not transcript levels.

20 ential mechanisms for age-related changes in transcript levels.

21 istically with drl1 mutants and reduced drl2 transcript levels.

22 duplicated segments exhibit dosage-dependent transcript levels.

23 criptional mechanism involved in reduced DMD transcript levels.

24 ex composition and abundance, independent of transcript levels.

25 mitochondrial size, genome copy number, and transcript levels.

26 these glucagon-induced messenger RNA (mRNA) transcript levels.

27 romoters, generating enhanced variability of transcript levels.

28 acids, appeared to be driven by increases in transcript levels.

29 that PHO2 and NRT1.1 influence each other's transcript levels.

30 Many methods for transcript-level abundance estimation reduce the computa

31 Yet, the inherent inferential uncertainty in transcript-level abundance estimation, even among the mo

32 investigation reveals that increased nascent transcript levels accompanying speckle association corre

33 P2A19 and CYP2C36) genes displayed different transcript levels across treated versus UNT.

34 es inversely correlates with alpha-satellite transcripts levels across cell lines and transcript leve

35 udied in terms of their in vitro and in vivo transcript levels after different treatments and their b

36 that regulate display of sLe(X) reveal high transcript levels among circulating monocytes and low le

37 ubstrates with extended 3'UTRs that gene- or transcript-level analyses of NMD often fail to detect.

38 In addition to conventional gene-level and transcript-level analyses, we also directly quantified p

39 ifferential testing methodology have enabled transcript-level analysis of RNA-seq data.

40 most accurate approaches, means that robust transcript-level analysis often remains a challenge.

41 transcripts in a data-driven manner allowing transcript-level analysis where it can be confidently su

42 Transcript level and activity labelling of cathepsin B w

43 n of T (porA) significantly reduced the porA transcript level and the expression of MOMP.

44 dence showed both a reduction in full-length transcript levels and an increase in levels of a shorter

45 so be effectively used for quantification of transcript levels and analysis of differential gene expr

46 Kismet positively influenced transcript levels and bound to dap160 and endophilin B t

47 +59 motif and the adjacent stem-loop on cagA transcript levels and cagA mRNA stability.

48 n environmental factor known to augment cagA transcript levels and CagA protein levels.

49 unoFISH to simultaneous quantify protein and transcript levels and distribution in cultured HER2 posi

50 insights into the relationship between gene transcript levels and HLA ligand presentation.

51 Quantitative PCR revealed higher Gabrd transcript levels and larger tonic currents in the VTA o

52 In contrast, male and female Gabrg2 transcript levels and measures of phasic inhibition were

53 e data revealed almost unaltered chloroplast transcript levels and only mild changes in ribosome occu

54 Na(+)/K(+) alpha1-subunit transcript levels and protein abundance were significant

55 eted, resulting in a 76% average decrease in transcript levels and recapitulation of well-known embry

56 181b from CDCs into Mvarphi reduces PKCdelta transcript levels and underlies the cardioprotective eff

57 sis thaliana), trigger widespread changes in transcript levels and whole-plant phenotypes, including

58 ciates with DNA repair and hormone-regulated transcript levels and with an early recurrent prostate c

59 NA metabolism, including increased pervasive transcripts levels and snoRNA processing defects.

60 rial size and protein content despite normal transcript levels, and aberrantly elevated phosphorylati

61 Total lung RNA was examined for transcript levels, and BALF was examined for cytokine pr

62 b exerts opposing roles in regulating GhSOS1 transcript levels, and ectopic expression of GhANN8b ele

63 decreased SOX9 protein expression and Col2a1 transcript levels, and increased apoptosis.

64 nt HIV-1 p24 levels, reduced CXCL10 and IL-6 transcript levels, and induced peroxisome proliferator-a

65 We develop a transcript-level annotation metric known as the 'proport

66 Transcript levels are a critical determinant of the prot

67 Patients with higher transcript levels are considered to respond better to th

68 1-2 plants apply also to 5S rDNA, changes in transcript levels are different for 45S and 5S rRNA, ind

69 PEPCK and G6Pase transcript levels are downregulated in hepatocytes from

70 A3, TCF7 (TCF-1), AHR, SOX4, RUNX2, and ZEB1 transcript levels are higher in CD56(bright) cells, whil

71 role of alternatively spliced MBSs affecting transcript levels are important for understanding plant

72 cdc25 transcript levels are regulated such that smaller cells

73 These findings demonstrate that transcript levels are useful for predicting traits and t

74 in 3D chromatin collude to influence target transcript levels as well as clinical risk.

75 n of NnCYP76B6 resulted in reduction of mRNA transcript levels as well as CPT content in comparison t

76 at the FRO2 locus leads to variation of FRO2 transcript levels, as well as ferric chelate reductase a

77 onic RNA sequences, some of them controlling transcript levels associated with glucagon action.

78 hermoregulation resulting in lower eftM mRNA transcript level at 37 degrees C compared to 25 degrees

79 ed upon iron deprivation and restores normal transcript levels at genes encoding mitochondrial protei

80 interaction networks with the differences in transcript levels between control and disease-does not r

81 nes with m6dA are associated with higher RNA transcript levels but identifies allele-specific gene tr

82 1 genes exhibited significant differences at transcript levels by microarray analysis were identified

83 oint mutation in PsbO-A1 or reduction in its transcript levels by RNA interference resulted in chloro

84 Furthermore, buds with high BRC1 transcript levels can be active.

85 Here, we show that TA transcript levels can increase substantially in response

86 However, it remains unclear how well transcript levels can predict traits, particularly when

87 gly supported fusions and fusions with large transcript level changes in the absence of multitumor re

88 6B6 showed a significant enhancement in mRNA transcript levels coincident with enhanced CPT accumulat

89 than other tuQTLs and constituted 25% of the transcript-level colocalisations with complex traits.

90 To characterize the transcript level component of metabolic regulation, geno

91 upancy at promoters is associated with lower transcript levels, consistent with local repressive effe

92 in's approach to UMI deduplication considers transcript-level constraints on the molecules from which

93 las revealed that YAP1 and androgen receptor transcript levels correlate with each other in prostate

94 amily members based on immunoblotting or RNA transcript levels correlated poorly with the activity of

95 High cytokine transcript levels correlated with increased protein prod

96 tps10 plants and plants with reduced MtTPS10 transcript levels created by expression of an MtTPS10-ar

97 during fruit development and ripening, with transcript levels decreasing more than protein levels.

98 However, increased transcript levels do not always translate into protein p

99 ients achieved a 3-log reduction in BCR-ABL1 transcript levels during consolidation.

100 ntitative RT-PCR analyses identified reduced transcript levels during stamen development and pollen t

101 showed that quantifying TE expression at the transcript level effectively reduces noise.

102 , even if the data strongly support specific transcript-level effects.

103 erences in expression units and gene- versus transcript-level estimation.

104 ted in other species to build a pipeline for transcript-level expression and alternative splicing ana

105 Nascent transcript level fold-increases for speckle-associated a

106 higher levels of ROS, the LEW rat had lower transcript levels for antioxidant enzymes (lactoperoxida

107 o achieve and maintain undetectable BCR-ABL1 transcript levels for at least 2 years remain disease-fr

108 Transcript levels for cytokines and the viral restrictio

109 hat the wild type ADAR3 protein can regulate transcript levels for DUSP1 and EGR1, suggesting a novel

110 er NF-kappaB activity, evidenced by elevated transcript levels for NF-kappaB family members, activati

111 Transcript levels for NF-kappaB pathway markers were ass

112 Severalfold higher nascent transcript levels for several Hsp70 flanking genes also

113 Transcript levels for the fifteen unique salmonid AMPK s

114 d levels (oxidized LDL, ox-LDL) and elevated transcript levels for the lipid scavenger receptor CD36

115 Using maize (Zea mays) genetic markers and transcript levels from seedlings to predict mature plant

116 d the STAT2 protein level, whereas the STAT2 transcript level had minimal change.

117 sequencing-based methods for profiling gene transcript levels have revealed substantial heterogeneit

118 At the transcript level, high PICALM in DecPDL and ESYT2 and LR

119 rogenitors, 5hmC did not correlate with gene transcript levels, however, upon differentiation the glo

120 The suppression of CLU was verified at transcript level in different melanoma cell lines, and a

121 ate interpretation of gene expression at the transcript level in endometrial cancer studies especiall

122 ighly expressed in TNN18 and TNG31; however, transcript levels in DBE and SBE were extremely low.

123 anscriptional studies have shown reduced DMD transcript levels in DMD patient and animal model muscle

124 High resolution genetic mapping of transcript levels in HMDP, reveals both local and trans

125 extensive variation in glycophorin B (GYPB) transcript levels in individuals from Benin, suggesting

126 JQ1 treatment reduces NADPH subunit transcript levels in mdx muscles, isolated myofibers and

127 Human specific ISG transcript levels in mouse liver increased significantly

128 e receptor 1 [duffy blood group]) whose mRNA transcript levels in plasma exosomes significantly incre

129 nt component 4A (C4A) alleles and higher C4A transcript levels in postmortem brain tissue.

130 ent to initiate a significant rescue of pth2 transcript levels in previously isolated zebrafish.

131 evident by microglial morphology or cytokine transcript levels in R6/2 mice.

132 s, we found that rate changes of genome-wide transcript levels in response to N-dose could be explain

133 ause termination is associated with enhanced transcript levels in several positive elements stimulati

134 of the expression of the gene discloses high transcript levels in several tumor tissues, such as germ

135 Restoring TOC1 transcript levels in shoots via micrografting was suffic

136 Vitellogenin transcript levels in the hepatopancreas increased in the

137 ssed in all tested bean tissues, with higher transcript levels in the root meristems and senesced nod

138 f SPL2 had reduced ASYMMETRIC LEAVES 2 (AS2) transcript levels in their siliques.

139 is associated with increased CD20 and IGF-1 transcript levels in tumors and IGF-1 expression in tumo

140 Changes in transcript levels in vts1Delta cells established the reg

141 ups of land plants and determinations of NLR transcripts levels in response to drought in white spruc

142 (lo) cells, without significant increases in transcript levels, in the absence of TCR signals.

143 reas AtGA2ox10 produces C(19)-GA(9) AtGA2ox9 transcript levels increase after cold treatment and AtGA

144 ite transcripts levels across cell lines and transcript levels increase substantially when the nucleo

145 e expression of miR319 declines while GhTCP4 transcript levels increase, with high levels of the latt

146 ive-cell imaging reveals that HSPA1B nascent transcript levels increase/decrease with speckle associa

147 was lost in the Deltakatms strain, and whose transcript levels increased in M. smegmatis biofilms alo

148 Specifically, jun-1 transcript levels increased in wild-type animals post ga

149 min A provides one example, with protein and transcript levels increasing with collagen 1 and tissue

150 al CDFs (CDF1, CDF3, CDF5) and increasing FT transcript levels, indicating both cis and trans functio

151 1 protein levels does not correlate with its transcript levels, indicating that MAF1 is regulated pos

152 changes in transcription, demonstrating that transcript levels influence specific productivity.

153 y single cell sequencing experiment in which transcript level information is needed beyond polyadenyl

154 well established that precise control at the transcript level is a key genetic underpinning of lung b

155 els of triacylglycerol accumulation, and the transcript level is directly correlated to the level of

156 Gene expression studies showed that OsNHX1 transcript level is highly induced by salt and PEG-induc

157 s, and 4) one inhibitor (IkappaBalpha) whose transcript level is itself regulated by NF-kappaB activi

158 r, both total HSPA1B mRNA counts and nascent transcript levels measured adjacent to the transgene are

159 Composite transcript level measures supported these findings by re

160 ometry, has lagged, however, behind gene and transcript-level observations.

161 From 6-HAI to 3-DAI, rapid changes in transcript level occurred, including starch and sucrose

162 CRC-risk allele C of rs7198799 with elevated transcript level of biological plausible candidate gene

163 Winspit showed the highest transcript level of BoMYB28, BoMYB29 and BoAOP2 genes, a

164 Loss of RBM4 resulted in an elevated transcript level of bound ERVs of the HERV-K and -H fami

165 e gfp coding sequence revealed that both the transcript level of gfp and its fluorescence signals wer

166 Our results indicated that in rice, transcript level of OsamiR395 (Oryza sativa miR395) incr

167 se mechanism by significantly increasing the transcript level of silicon transporter genes (EcLsi1, E

168 A expression analysis, and compared baseline transcript levels of 109 genes important in volume-overl

169 action between CcpA and HPr and impacted the transcript levels of 205 genes (40%) in the total CcpA r

170 ately 7,200 eQTL regulating the steady-state transcript levels of 5,300 genes.

171 hIP-seq approach, we found that CcpA affects transcript levels of 514 of 1667 GAS genes (31%) whereas

172 Then, we measured transcript levels of a group of these genes in primary m

173 native polyadenylation (APA) profiles and/or transcript levels of a subset of genes.

174 Transcript levels of all four genes in peripheral blood

175 velopment under salt stress by affecting the transcript levels of aquaporins, as well as CYP79B2, an

176 rs of schizophrenia and comparison subjects, transcript levels of ARP2/3 complex signaling pathway we

177 Transcript levels of ARP2/3 complex subunits and of nucl

178 d stress conditions and, thus, adjusting the transcript levels of CAT2.

179 Protein and transcript levels of cell cycle regulators were examined

180 In mutants lacking PpNOG2 function, transcript levels of CLAVATA and SCARECROW genes are sig

181 oding RNAs, whose levels correlated with the transcript levels of coding genes in cis, were different

182 Sse(A+) SpeB(A+) variants had transcript levels of CovRS-controlled virulence genes co

183 the uninfected LEW rat has inherently higher transcript levels of cytochrome enzymes (Cyp2d3, Cyp2d5,

184 The mRNA transcript levels of each gene were calculated.

185 nt in Tenera was associated with much higher transcript levels of EgWRI1, homolog of Arabidopsis thal

186 e dissected in greater detail the changes in transcript levels of elements of several signaling pathw

187 This is consistent with transcript levels of enzymes involved in the alternate p

188 ells and cartilage, concomitant with reduced transcript levels of Fgf10 in Dermo1-Cre;Ctnnb1(loxp/lox

189 posure resulted in a significant decrease in transcript levels of five aflatoxin genes and at least t

190 In the mutant, the transcript levels of genes for PSI structural and access

191 Transcript levels of genes involved in alternative pathw

192 Transcript levels of glutaminolytic factors were quantif

193 otocols for the quantitative analysis of the transcript levels of HTTexon1 in human tissue and applie

194 Transcript levels of IL-12p35, IL-12/23p40 and IL-23p19

195 blood cells demonstrated a marked change in transcript levels of immune and metabolic genes 24 hours

196 utated mouse fibroblasts expressed increased transcript levels of insulin-like growth factor 1 (Igf1)

197 We show that HCV modulates the transcript levels of key enzymes of glutamine metabolism

198 Reduced transcript levels of KLF2 in IPAH-PAAFs was augmented by

199 individuals revealed a dramatic reduction in transcript levels of low-density lipoprotein receptor (L

200 id as the sole carbon source and had reduced transcript levels of major beta-oxidation genes.

201 type mice, which coincided with altered mRNA transcript levels of MCP-1, Cx43 and TGFbeta.

202 f ROS within the first 30 min, and increased transcript levels of mechano-inducible genes within 60 m

203 multiple nucleopolyhedrovirus (AcMNPV), the transcript levels of most SNARE genes initially were upr

204 We also found that transcript levels of MSN2/MSN4 are increased in glucose-

205 Here, we found that protein and transcript levels of nescient helix loop helix 2 (NHLH2)

206 F-kappaB activation and a marked increase of transcript levels of NF-kappaB inhibitors, IkappaBalpha

207 s a negative correlation between protein and transcript levels of nuclear DNA- but not mtDNA-encoded

208 et because its inhibition leads to decreased transcript levels of oncogenic transcription factors, es

209 ese peak levels corresponded positively with transcript levels of overlapping genes.

210 their peak levels corresponded inversely to transcript levels of overlapping genes.

211 was performed at several stages to determine transcript levels of PACAP and corresponding receptors.

212 In this study, sequences and transcript levels of peanut CSD1 isoforms (AhCSD1-1, AhC

213 Transcript levels of PgUGT5b were higher than those of P

214 Moreover, transcript levels of PYP1, 2 and 6 genes in peel and pul

215 latelet-derived growth factor alpha and high transcript levels of Rars, Cxcl12, and stem cell factor

216 Atg5/7-deficient TM cells showed changes in transcript levels of several fibrotic genes, including T

217 nts of GA3 and cytokinins due to upregulated transcript levels of several plastidic 2-C-methyl-d-eryt

218 ferentially expressed genes, among which the transcript levels of some of the heat shock protein gene

219 in G. bimaculatus Here we show that reducing transcript levels of some or all of these Hox genes resu

220 This coincided with increased transcript levels of some senescence-specific and pathog

221 sistent with substantial upregulation of the transcript levels of specific pathogen-responsive genes.

222 ecently shown in Caenorhabditis elegans that transcript levels of sqst-1/p62 increase upon a hormetic

223 , STAT3 inactivity was transient because the transcript levels of STAT3 and its inhibitors, including

224 roles during plant development by regulating transcript levels of target mRNAs, maintaining genome in

225 nse, contrasting with the marked increase in transcript levels of the anti-M. marinum invariant TCR r

226 and effect of this accumulation, we followed transcript levels of the cytokinin biosynthetic pathway

227 n, whereas ssGnih-2 treatment did not affect transcript levels of the main reproductive genes.

228 iRNA pathway components do not act to reduce transcript levels of the P-element transposon during P-M

229 Moreover, the transcript levels of the porin genes, ompD, ompF, and om

230 y ZIKV, which was confirmed by analyzing the transcript levels of the proteins of inflammasome pathwa

231 Dosage compensation is the process by which transcript levels of the X chromosome are equalized with

232 ns-jasmonic acid, and abscisic acid) and the transcript levels of their biosynthetic genes.

233 MART-seq, can reveal simultaneously the mRNA transcript levels of thousands of genes in thousands of

234 Furthermore, transcript levels of TPCs correlated negatively with p62

235 nt, which implies coordinated changes in the transcript levels of ZmFDL1/MYB94 and associated genes.

236 or infected with Dengue virus revealed high transcripts levels of genes associated with lipid storag

237 es, induced a time-dependent increase of the transcripts levels of specific glucose and lactate trans

238 ne expression, as evidenced by the fact that transcript levels often poorly correlate with protein le

239 d that amp1 has no significant effect on SPL transcript levels, or on the level or the activity of mi

240 ession simulations often assume steady-state transcript levels, or they model transcription in more d

241 reverse transcription-PCR revealed decreased transcript levels (P<0.04, n >/=5/group) for five other

242 modules revealing novel associations between transcript level patterns and biological processes.

243 netic hot spots regulating a large number of transcript level patterns relating to diverse biological

244 is and affects the expression of genes whose transcript levels peak during mitosis.

245 gnificantly correlated with intrarenal GDF15 transcript levels (r=0.54, P=0.01).

246 These variants act largely through transcript level regulation.

247 anges, hepatic leukocyte population, hepatic transcripts level related to leukocyte recruitment, and

248 entified modules were shown to have a higher transcript level relationship (i.e. connectivity) in tre

249 is not mediated by abnormal telomerase gene transcript levels relative to those of endogenous genes.

250 demonstrated that, during sporulation, codY transcript levels remained high in SM101 but rapidly dec

251 width under HNT is a result of differential transcript-level response of Fie1 in grains developing u

252 rential uncertainty is too high to support a transcript-level result.

253 genes involved in protein folding, and most transcript levels returned more slowly to baseline, so t

254 d in innate immunity and apoptosis, and most transcript levels returned to baseline many hours before

255 ignment approaches are the tool of choice in transcript-level RNA sequencing (RNA-seq) analyses.

256 ogy, but decreases inflammation-related gene transcript levels selectively late in disease progressio

257 GENASE 7 (CCD7) and CCD8 revealed that their transcript levels showed significant variation in P. aeg

258 ine self-administration increased BNST PACAP transcript levels similar to what we have previously rep

259 the knockout mice, reconstitution of Ormdl3 transcript levels specifically in the bronchial epitheli

260 ying thousands of genetic variants affecting transcript levels (strength) or the distribution of TSSs

261 transcripts tended to increase, whereas GABA transcript levels tended to decrease, from caudal to ros

262 On the transcript levels, th mRNA inversely correlated with dop

263 DWARF1 (DWF1) lead to variation of the DWF1 transcript level that contributes to natural variation o

264 eat expansion to upregulate normal variant 1 transcript levels, the defective vesicle trafficking and

265 ouchless phenotypes to downregulated sorbs3 transcript levels, this work re-attributes the phenotype

266 PIK3CD is regulated at the transcript level through alternate use of 5' untranslate

267 activation, whereas the other maintains high transcript levels throughout stimulation.

268 n precursor, vitellogenin, and monitored its transcript levels throughout the entire shrimp life-cycl

269 LSCs have predominantly been studied at the transcript level, thus information about posttranscripti

270 We assessed both reduction of RUNX1-RUNX1T1 transcript levels (TLs) and achievement of MRD negativit

271 We determined NPM1mut transcript levels (TLs) by quantitative reverse-transcri

272 Intersection of EWAS, transcript level to trait association, and eQTM results,

273 Here, we present global analyses of viral transcript levels to further understand the roles of the

274 We have developed methods to normalize PMP22 transcript levels to SC-specific genes that are not alte

275 We sought to estimate the contribution of transcript levels to these two orthogonal sources of var

276 To accurately measure changing gene transcript levels under different experimental condition

277 The ability to control Myd88 transcript levels using a CRISPR-based synthetic repress

278 , read alignment, quantification of gene and transcript levels, visualization, differential gene expr

279 pproaches for predicting protein levels from transcript levels, we discuss challenges and potential s

280 Importantly, lower CYP27A1 transcript levels were associated with shorter disease-f

281 Transcript levels were decreased by small interfering RN

282 The var gene transcript levels were determined in early and late post

283 GFP and ONE HELIX PROTEIN1 transcript levels were downregulated by up to 90%, and G

284 ound that despite the lack of protein, CLASP transcript levels were higher in dark-grown root tips.

285 Both metabolite and transcript levels were higher in skin than in flesh and

286 t1 plants, except for developing seed, where transcript levels were higher in the dgat1 mutant.

287 In cold, COR gene transcript levels were increased in flc and pep1-1 mutan

288 nder different stress conditions showed that transcript levels were increased with dehydration, sodiu

289 phenotype in mice and humans, and muscle EGF transcript levels were raised in COPD.

290 SERCA2A mRNA transcript levels were reduced in HCM regardless of geno

291 oters of SAGs were hypermethylated and their transcript levels were remarkably reduced, and leaf sene

292 The Cancer Genome Atlas revealed that SLAMF7 transcript levels were strongly correlated with various

293 upregulated muscular and adipose Pgc-1alpha transcript levels, whereas exercise alone was incapable

294 sMYC2 showed significant enhancement of mRNA transcript levels which corroborated well with the enhan

295 hment of latent cells harboring higher viral transcript levels, which can reactivate more efficiently

296 ion studies and methods for examining global transcript levels, which gave rise to the field of "inte

297 pression resulted in inverse changes in WWOX transcripts levels with siRNA interference eliminating P

298 base in gene bodies positively correlated to transcript levels, with more than 2000 genes stably mark

299 localization of PyrKII resulted in decreased transcript levels within the apicoplast that preceded or

300 methylation and copy number integration with transcript levels yielded an assessment of their relativ