ライフサイエンスコーパス: transcription activation

1 y is essential for its chromatin binding and transcription activation.

2 he Grr1 ubiquitin ligase, thereby preventing transcription activation.

3 t enhancers occurs and how this is linked to transcription activation.

4 e lead to histone acetylation and consequent transcription activation.

5 quitination of the activator is critical for transcription activation.

6 nteraction to rapidly initiate Gal4-mediated transcription activation.

7 nating functions of diverse cofactors during transcription activation.

8 am promoter regions can achieve programmable transcription activation.

9 irements of the SaeR binding sites in P1 for transcription activation.

10 ding the molecular mechanism of sae-mediated transcription activation.

11 binding to phosphorylated SaeR (P-SaeR) and transcription activation.

12 e 3 methylation, H3 Lys9/14 acetylation, and transcription activation.

13 the capability to induce the metal-specific transcription activation.

14 overexpression, solubility, DNA binding, and transcription activation.

15 ongation has emerged as a major mechanism of transcription activation.

16 I) box required for HrpB-dependent T3SS(rso) transcription activation.

17 ptor-linked elevation of cAMP leading to CRE transcription activation.

18 ral transitions required for DNA binding and transcription activation.

19 ctor that facilitates nuclear relocation for transcription activation.

20 at NFAT2 cooperates with Sp1 to promote Bmp7 transcription activation.

21 ay between CmSvp and CmHNF-4 controls CmCatB transcription activation.

22 via UBF hyperphosphorylation leading to rRNA transcription activation.

23 motifs of NS5A seem to be essential for rRNA transcription activation.

24 ivities in addition to beta-catenin-mediated transcription activation.

25 owed by recruitment of RNA polymerase II and transcription activation.

26 cT1 to enhance RNA affinity and consequently transcription activation.

27 target genes specifically without off-target transcription activation.

28 teins undergo structural changes that enable transcription activation.

29 R-CTD was capable of only very low levels of transcription activation.

30 both increased intron retention and reduced transcription activation.

31 ay use multiple weak binding sites to aid in transcription activation.

32 terns of acetylated lysines in C/EBPbeta for transcription activation.

33 orylation at Y705, nuclear localization, and transcription activation.

34 as important biological implications such as transcription activation.

35 g the potential for combinatorial control of transcription activation.

36 ulted in strong inhibition of LNO(2)-induced transcription activation.

37 her potentiated by androgen via AR-dependent transcription activation.

38 ing gene expression during the first wave of transcription activation.

39 ing a higher potency, specificity, and lower transcription activation.

40 l roles for H3K9 methylation and HP1gamma in transcription activation.

41 imity to the activator during the process of transcription activation.

42 ion, the MCM proteins are also necessary for transcription activation.

43 that p32 specifically inhibits CBF-mediated transcription activation.

44 esting that phosphorylation is necessary for transcription activation.

45 h of the protein interaction correlates with transcription activation.

46 responsible for triggering the GabR-mediated transcription activation.

47 ese genes result in chromatin remodeling and transcription activation.

48 ssed genes into proximity with enhancers for transcription activation.

49 of expression due to differential timing of transcription activation.

50 nome organization, focal RF accumulation and transcription activation.

51 ter, which plays a key role in HpdR-mediated transcription activation.

52 ween TAP and RNAP holoenzyme responsible for transcription activation.

53 itinated histone H2B plays multiple roles in transcription activation.

54 ed by hnRNP K, which leads to a low level of transcription activation.

55 in (SID) and basic linker are sufficient for transcription activation.

56 ToxR recruits TcpP to the toxT promoter for transcription activation.

57 that depends on neither ADK inactivation nor transcription activation.

58 s chromatin remodeling at these loci without transcription activation.

59 with CAD/MI in one family, and it suppresses transcription activation activity of MEF2A by a dominant

60 e residues abolishes or markedly reduces the transcription activation activity of MTF1 and the abilit

61 vity of Ubc9 seems to be dispensable for the transcription activation activity of RHA.

62 nteract with each other and show synergistic transcription activation activity.

63 eet curly top virus (genus Curtovirus) lacks transcription activation activity.

64 ilencing spread by a mechanism that requires transcription activation activity.

65 al system in which the DNA-binding (DBD) and transcription-activation (AD) domains of a transcription

66 vant mechanisms for facile switching between transcription activation and deactivation in vivo and in

67 the ToxR-footprinted region were tested for transcription activation and DNA binding.

68 s also reveals a consistent role of NEDD4 in transcription activation and H3 K9 acetylation in respon

69 NF-kappaB transcription activation and increased Bcl-xL expression

70 ressing signal transducers and activators of transcription activation and inhibiting T-cell different

71 ation of histone H2B plays a central role in transcription activation and is required for downstream

72 otein-coding genes is a key event in RNAP II transcription activation and is the first and rate-limit

73 tor-binding domains contribute additively to transcription activation and Mediator recruitment at Gcn

74 g nucleosome disassembly at promoters during transcription activation and nucleosome reassembly at co

75 Sepsis is encoded by a sequel of transcription activation and repression events that init

76 s reflected in enhanced Spx activity in both transcription activation and repression in cells express

77 played a characteristic profile of intrinsic transcription activation and repression, binding with pr

78 one-DNA complexes, as well as in deregulated transcription activation and repression.

79 ve detailed the role of E2F proteins in both transcription activation and repression.

80 Histone methylation is associated with both transcription activation and repression.

81 -promoter looping from nuclear migration and transcription activation and reveal new roles for LDB1 i

82 4-NUT oncoprotein recruits p300 to stimulate transcription activation and that inhibition of p300 rep

83 equired for glucocorticoid receptor-mediated transcription activation and that its activity is regula

84 direct mechanisms, with resulting effects on transcription activation and the coupling of rRNA synthe

85 dent and the contrasting sigma(54)-dependent transcription activations and thus potentially underlie

86 iated protein degradation, Golgi reassembly, transcription activation, and cell cycle control.

87 with SAGA, show a corresponding decrease in transcription activation, and fail to recruit TBP to a S

88 le nuclear events including DNA replication, transcription activation, and gene silencing.

89 ally impaired SpCas9 technologies, including transcription activation, and identified a pharmacophore

90 domains (CTDs) that mediate DNA-binding and transcription activation, and N-terminal domains (NTDs)

91 conserved bridge between the NSL complex and transcription activation, and provide a new perspective

92 ositively correlates with ethylene-regulated transcription activation, and the elevation requires EIN

93 ndosome disruption, subcellular trafficking, transcription activation, and virus assembly.

94 This DNA-protein architecture for transcription activation appears to be conserved for Com

95 t chemical sensing, receptor activation, and transcription activation are integrated at the receptor

96 However, the mechanisms controlling their transcription activation are not well understood.

97 These alterations influence transcription activation, as well as repression.

98 e if Btk is important for Bright function, a transcription activation assay was established and analy

99 mal activity (partial agonism) in cell-based transcription activation assays and attenuated gene sign

100 One-hybrid transcription activation assays revealed that KRBDP3, bu

101 osome (MMTV-B) that is the initial target of transcription activation-associated processes on this pr

102 facts that MSL1/2 activity is important for transcription activation at HOXA9 and MEIS1 loci and tha

103 Additionally, transcription activation at specific TEs and TE-adjacent

104 etylation and for the prevention of constant transcription activation at the chromatin level for reso

105 sociated with xKaiso depletion are premature transcription activation before the mid-blastula transit

106 These cations are not only required for transcription activation but also directly involved in t

107 y, the chromatin binding is required for FUS transcription activation, but not for alternative splici

108 etyltransferase MOF plays important roles in transcription activation by acetylating histone H4 on K1

109 Further, we demonstrated that transcription activation by AdcR occurs by direct bindin

110 Transcription activation by androgen receptor (AR), whic

111 uding ATXN7L3B, which couples mRNA export to transcription activation by association with the TREX-2

112 have shown stringent spacing is required for transcription activation by CRP.

113 Transcription activation by cyclic AMP (cAMP) receptor p

114 Transcription activation by distal enhancers is essentia

115 Our data provides a novel mechanism for transcription activation by FOXP3 and a genetic mechanis

116 on or inhibition of the proteasome function, transcription activation by Gis1 is no longer solely con

117 AGA-type complexes in cell proliferation and transcription activation by MYC postloading of TFIID and

118 n other nuclear receptors is responsible for transcription activation by recruiting coactivators thro

119 la homeotic gene Ultrabithorax (Ubx) mediate transcription activation by recruiting the epigenetic re

120 ntains all of the determinants necessary for transcription activation by RhaS.

121 To understand the mechanism of transcription activation by RopB, we determined the crys

122 he 15-LOX-1 promoter, which allowed 15-LOX-1 transcription activation by SAHA.

123 but nothing is known about the mechanisms of transcription activation by Staf.

124 c nitrate reductase results from synergistic transcription activation by the Fnr and phospho-NarP pro

125 a "core" form of the Mediator complex during transcription activation by the MYC oncoprotein.

126 creased nuclear delivery by TAT chimeras and transcription activation by the pluronic.

127 The mechanism of transcription activation by these TetR-type transcriptio

128 uggest that Atro is required to modulate the transcription activation by Trl in larval imaginal discs

129 Overall, SE-1 appears to inhibit transcription activation by VirF, exhibits selectivity t

130 , we show that knockdown of HDAC5 results in transcription activation by YY1.

131 Transcription activation causes dramatic changes in a ge

132 ion of ECs is responsible for Elk-1-mediated transcription activation (chromatin immunoprecipitation

133 lysis of the 3AT-induced genes suggests that transcription activation coincides with rearrangement of

134 tact Escherichia coli class-II CAP-dependent transcription activation complex (CAP-TAC) with and with

135 ing the class I mechanism requires an intact transcription activation complex (TAC) structure at a hi

136 report a cryo-EM structure of a B. subtilis transcription activation complex comprising B. subtilis

137 and is associated with the endogenous NOTCH1 transcription activation complex in human T-ALL leukemic

138 ses association of the GATA-1.TAL1.LMO2.LDB1 transcription activation complex to the region that incl

139 ream mediators of Notch signaling, the Notch transcription activation complex, remains largely unexpl

140 ecule inhibitor (termed CB-103) of the Notch transcription activation complex.

141 al structure of an intact bacterial class II transcription activation complex.

142 Integration of protein kinases into transcription activation complexes influences the magnit

143 Further, the levels of transcription activation correlate with the strength of

144 This mechanism explains how transcription activation cycles, lasting for tens of min

145 ional bursts are an inherent feature of such transcription activation cycles.

146 The presence of ToxR suppressed transcription activation defects associated with most, b

147 ooping, we expressed a looping-competent but transcription-activation deficient form of LDB1 in LDB1

148 Ordered 5' deletions revealed that transcription activation depended on sequences located u

149 amage within active chromatin in a PCNA- and transcription activation-dependent manner.

150 and activates transcription via a C-terminal transcription activation domain (AD).

151 ently, a serine phosphorylation event in the transcription activation domain (serine 727 for Stat1) o

152 ory domain, the N terminus of Myc contains a transcription activation domain (TAD) that recruits cofa

153 r gene activation by tethering an autonomous transcription activation domain (TAD) to an intended gen

154 (sTALE), the TALE DNA binding domain and the transcription activation domain are separated and each f

155 comparison with typical TALEs, iTALEs lack a transcription activation domain but retain nuclear local

156 poptosis and transformation, where the ESE-1 transcription activation domain contributes to apoptosis

157 kably, we also observed that AL2 lacking its transcription activation domain could reverse TGS in rep

158 e N-terminal extension of HDAC5 and the VP16 transcription activation domain fused to 14-3-3.

159 the smaller variants, is part of the second transcription activation domain in Gis1 and is essential

160 s a truncated CBF-B subunit, Bdbd, lacking a transcription activation domain in various mammalian cel

161 quitously expressed nuclear factor PTIP (pax transcription activation domain interacting protein).

162 d YAP1 phosphorylation at three sites in its transcription activation domain is necessary for SRC-YAP

163 hat a novel dimerization interface in the E2 transcription activation domain is stabilized by a disul

164 ZNF644 and WIZ interact with the transcription activation domain of G9a and GLP, respecti

165 Paradoxically, the transcription activation domain of GATA4 is dispensable

166 3, indicating that this motif is part of the transcription activation domain of Glis3.

167 ession domains of KLF3 plus the MADS box and transcription activation domain of SRF are implicated in

168 removal of the intrinsically-disordered YAP transcription activation domain prevented the formation

169 By fusing transcription activation domain to Pseudomonas aeruginos

170 nteracts with ten binding sites in the ASCIZ transcription activation domain, and high DYNLL1 levels

171 multiple independent ways: by binding to its transcription activation domain, inhibiting p53 acetylat

172 a docking site on Mediator for the ATF6alpha transcription activation domain.

173 ts domain, and NRF-2beta, which contains the transcription activation domain.

174 lA/p65, the NF-kappaB subunit endowed with a transcription activation domain.

175 ets domain, and GABPbeta, which contains the transcription activation domain.

176 could inducibly ablate PAX interacting (with transcription-activation domain) protein 1 (PTIP), a key

177 Acidic transcription activation domains (ADs) are encoded by a

178 For example, do intrinsically disordered transcription activation domains (ADs) use sequence-spec

179 Recently, the recruitment of multiple transcription activation domains by a single sgRNA, modi

180 A cleavage activity could be used to recruit transcription activation domains to specific promoters.

181 machinery, conserved coactivator complexes, transcription activation domains, and the cooperation of

182 consisting of the MS2 coat protein linked to transcription activation domains, was reported to induce

183 n, the E proteins share two highly conserved transcription activation domains.

184 ncoded by WDSV, has separable cyclin box and transcription activation domains.

185 into two parts encoding its DNA-binding and transcription-activation domains.

186 , E4BP4#2, AP3, and LVa sites contributed to transcription activation driven by the WDSV U3 region.

187 globin locus control region and gene and for transcription activation during erythroid differentiatio

188 They are responsible for sigma(54)-dependent transcription activation during infection and function u

189 Activation of pla expression requires a transcription activation element of the pla promoter tha

190 AC-7 (no apical meristerm (NAM), Arabidopsis transcription activation factor (ATAF) and cup-shaped co

191 C (for no apical meristem [NAM], Arabidopsis transcription activation factor [ATAF], and cup-shaped c

192 in-containing no apical meristem/Arabidopsis transcription activation factor/cup-shaped cotyledon tra

193 uced NAC (for NO APICAL MERISTEM/ARABIDOPSIS TRANSCRIPTION ACTIVATION FACTOR/CUP-SHAPED COTYLEDON) tr

194 on factor Arabidopsis (Arabidopsis thaliana) Transcription Activation Factor1 (ATAF1) plays an import

195 ORYZA SATIVA No Apical Meristem, Arabidopsis Transcription Activation Factor1-2, Cup-Shaped Cotyledon

196 nt DNA sequences and interact with different transcription activation factors.

197 Transcription activation from the sigma(A)-dependent bmr

198 isrupts the binding with RBF but retains the transcription activation function does not mimic the eff

199 Interestingly, while removing the transcription activation function of dE2F1 is sufficient

200 red at two additional steps to stimulate the transcription activation function of MondoA-Mlx complexe

201 C171S disrupted Zta transcription activation function of several EBV lytic c

202 ation of EBV but had only a modest effect on transcription activation function.

203 to mammals, with some family members having transcription activation functions and others having rep

204 t do not depend on beta-catenin/Tcf-mediated transcription activation has long been understood.

205 estigated the role of amino acid residues in transcription activation in a LytTR domain-containing tr

206 Then the levels of transcription activation in a Mtx-DHFR yeast three-hybri

207 d that it is essential for HrpB(bp)-mediated transcription activation in both species.

208 wo MOF complexes regulate distinct stages of transcription activation in cooperation with other histo

209 n and subsequent Smad2/3 phosphorylation and transcription activation in human cholangiocarcinoma cel

210 isomal vectors for the specific gamma-globin transcription activation in its native position by activ

211 ther dissect mechanisms of RF clustering and transcription activation in mouse embryonic stem cells.

212 or SMARCA4/Brg1 is required for Gli-mediated transcription activation in Sonic hedgehog (Shh) signali

213 base pairs identified as most important for transcription activation in the mutagenesis experiments.

214 for linking membrane electrical dynamics to transcription activation in the nucleus.

215 Members of this class had higher transcription activation in vitro than in vivo.

216 s in close physical proximity to Gal4 during transcription activation in vitro.

217 three recognition elements are required for transcription activation in vivo and for specific DNA bi

218 of each variant correlated with its level of transcription activation in vivo.

219 rase) complex performs multiple functions in transcription activation including deubiquitinating hist

220 ents have identified the proteins needed for transcription activation, initiation complex assembly, a

221 Transcription activation involves RNA polymerase II (Pol

222 etween these two membrane-bound proteins and transcription activation is difficult using ensemble met

223 Transcription activation is enhanced by elongating the c

224 operate on NFAT and contribute positively to transcription activation is not clear.

225 module component Med3, which is required for transcription activation, is suppressed by the kinase ac

226 onas oryzae pv. oryzae is dependent on major transcription activation-like (TAL) effector genes, and

227 nstrated that SE-1 inhibited DNA binding and transcription activation (likely by blocking DNA binding

228 E253A-DNA and E253Q-DNA complexes support a transcription activation mechanism requiring the expulsi

229 ecently discovered Conserved Motif IX-1/EDLL transcription activation motif of MED25-interacting AP2/

230 uppression mechanism that depends on neither transcription activation nor ADK inactivation.

231 In the mouse embryo, the major wave of transcription activation occurs at the 2-cell stage, but

232 Signaling associated with transcription activation occurs through posttranslationa

233 We demonstrate transcription activation of 8 genes by HilD; four of the

234 Transcription activation of a gene involves the ordered

235 Notch (ICN) is a protooncogene linked to the transcription activation of a number of cellular genes i

236 Transcription activation of both sets is regulated posit

237 ent assays, CTCF facilitated EBNA1-dependent transcription activation of Cp, suggesting that CTCF coo

238 main of CBF-B plays an essential role in the transcription activation of Cyclin B1 and Aurora A genes

239 dbd strongly suppressed cell cycle-dependent transcription activation of Cyclin B1, Aurora A and CDK1

240 d in endothelial cells upon CRISP-R-promoted transcription activation of each pair component, and als

241 e also show that C189S was not defective for transcription activation of EBV early gene promoters.

242 Camptothecin inhibited the Zta transcription activation of endogenous and reporter-link

243 expression of multiple gRNAs for synergistic transcription activation of follistatin when used with c

244 gulatory system and (ii) by extensive direct transcription activation of genes encoding structural pr

245 ation event robustly suppresses p53-mediated transcription activation of highly responsive target gen

246 Accumulation of nuclear beta-catenin and transcription activation of lymphoid enhancer factor 1 (

247 rther enhanced the level of Vpr-Sp1-mediated transcription activation of p21 through the sequence spa

248 -MSL1v1 is specifically required for optimal transcription activation of p53 target genes both in vit

249 between ToxT and RNA polymerase occur during transcription activation of promoters having different t

250 d the alpha-subunit and result in defects in transcription activation of quorum-sensing genes in vivo

251 C189S was deficient for transcription activation of several viral late genes tha

252 technique to show that MCM5 is essential for transcription activation of Stat1 target genes.

253 tion strain, LuxR is no longer necessary for transcription activation of the bioluminescence genes, s

254 assembly of the efflux complex ahead of the transcription activation of the cus operon for defending

255 YY1-binding site have only minor effects on transcription activation of the full-length 5'-UTR and L

256 To explore the role of TAL1 in transcription activation of the human gamma-globin genes

257 the ability of PML-RARalpha to attenuate the transcription activation of the Notch signaling downstre

258 virus (KSHV) lytic cycle can be initiated by transcription activation of the ORF50 immediate early ge

259 iated herpesvirus (KSHV) can be initiated by transcription activation of the ORF50 immediate-early (I

260 the interface is also required for selective transcription activation of viral latent cycle genes req

261 CF/LEF) transcription factors and subsequent transcription activation of Wnt-target genes.

262 ly, both activities are required for optimal transcription activation on a chromatin template in vitr

263 Transcription activation on chromatin templates is enhan

264 blocker, inhibiting promoter remodeling and transcription activation only when placed between the en

265 ts on sigma(70) region 1.1, are critical for transcription activation or inhibition, depending on the

266 o key transcription factors on the immediate transcription activation or repression of all genes regu

267 hat confer defects in positive control, i.e. transcription activation, or in specific DNA binding.

268 cation of new intermediate stages within the transcription activation pathway.

269 the amino-terminal portion of NUP98 exhibits transcription activation potential.

270 to other cellular Rel/NF-kappaB dimers with transcription activation potential.

271 histone variant H2AZ (Htz1) is implicated in transcription activation, prevention of the ectopic spre

272 he initial events of the sigma(54)-dependent transcription activation process.

273 of these residues in the sigma(54)-dependent transcription activation process.

274 acid residues in the LytTR domain of AgrA to transcription activation remains elusive.

275 We uncovered that CXXC5, although lacks a transcription activation/repression function, participat

276 lcineurin-mediated signal that culminates in transcription activation/repression of a large number of

277 Full-length AR and AR-V7 transcription activation required both PRMT5 and pICln b

278 that does not interact with HDAC5 results in transcription activation, suggesting that HDAC5 is neces

279 DNA upstream of the -35 promoter element for transcription activation suggests that delta functions a

280 Features of this transcription activation system suggest explanations for

281 thasone-inducible derivative of the pOp/LhG4 transcription activation system, and its use in tobacco

282 ndromic regions of the leader, including the transcription activation (TAR), polyadenylation (PolyA),

283 alpha, a mutant defective in DNA binding and transcription activation that failed to induce granulocy

284 se a new mechanism by which CAP triggers the transcription activation that is based on an order to di

285 arginine 17 (H3R17me2a) are associated with transcription activation, the mechanism by which CARM1 a

286 erminal DNA recognition helix interfere with transcription activation, thereby indicating that TetD d

287 Functioning at a level comparable to natural transcription activation, this activator is isolated to

288 he inducer GAL1, leading to a more sensitive transcription activation threshold, an alteration of met

289 e-specific DNA-binding protein that mediates transcription activation through its interactions with t

290 entifies BTBD18 as a specific controller for transcription activation through RNA polymerase II elong

291 For maximal hnRNP K transcription activation, two additional cytosine runs,

292 t the spacing requirements for CRP-dependent transcription activation vary according to the sequence

293 c ligand capable of triggering GabR-mediated transcription activation via formation of an external al

294 However, when PPARgamma-dependent transcription activation was examined, there were signif

295 oxal 5'-phosphate and GABA for GabR-mediated transcription activation was shown in vivo.

296 STAT3 (signal transducer and activator of transcription) activation was reduced, and Akt (protein

297 dification of beta-catenin and its effect on transcription activation, we confirmed dependence of S67

298 and PhoP(R200A)) that specifically affected transcription activation were broadly distributed throug

299 to be the most potent in PPARgamma-dependent transcription activation, whereas the weaker PPARgamma a

300 ght on the broader process of membrane-bound transcription activation which, although uncommon, has b