ライフサイエンスコーパス: transcription factor ATF

1 to three families: jun, fos, and activating transcription factor (ATF).

2 (CRE)-binding protein (CREB) and activating transcription factor (ATF) 1 contributes to melanoma pro

3 taR-II promoter, and we demonstrate that the transcription factor ATF-1 binds to this site and strong

4 hat human histone acetyltransferase GCN5 and transcription factor ATF-1 can potentiate CFTR transcrip

5 producing E. coli mutant, including the bZip transcription factor atfs-1 (activating transcription fa

6 eruginosa partially dependent on the UPR(MT) transcription factor atfs-1 and fully dependent on mitop

7 , a transcriptional response mediated by the transcription factor ATFS-1 that promotes the recovery a

8 (mt)) is a signaling pathway mediated by the transcription factor ATFS-1 which harbors a mitochondria

9 iptional loop that involves the mito-nuclear transcription factor ATFS-1, and a previously unknown an

10 ive transcriptional program regulated by the transcription factor ATFS-1, which induces genes that pr

11 s shown that the UPR(mt) is regulated by the transcription factor ATFS-1, which is regulated by organ

12 tochondrial protein import efficiency of the transcription factor ATFS-1, which mediates the mitochon

13 The key regulator of this process is the transcription factor ATFS-1, which, upon UPRmt activatio

14 aenorhabditis elegans, we find that the bZIP transcription factor ATFS-1/Atf5 (refs.

15 that: (i) PGN induced phosphorylation of the transcription factors ATF-1 and CREB; (ii) ATF-1 and CRE

16 Together, these studies suggest that the transcription factors ATF-1 and NF-Y play important role

17 We show that HOE-1 acts via transcription factors ATFS-1 and DVE-1 that are crucial

18 ncluding c-Myc, Elk-1, c-Jun, and activating transcription factor (ATF) 2 was also differentially enh

19 anisomycin, a potent activator of activating transcription factor (ATF) 2, and c-Jun-NH(2)-kinase, in

20 exes with the AP-1 family members activating transcription factor (ATF) 2, ATF3, and ATF7.

21 otein (SMAD)-3 (nt -584 to -581), activating transcription factor (ATF)-2 (nt -571 to -568), IRF-7 (n

22 p38 target transcriptional factor activating transcription factor (ATF)-2 bound to the PTEN promoter,

23 nd CRE-binding protein (CREB) and activating transcription factor (ATF)-2 in vitro and was essential

24 tivation of p38 kinase substrate, activating transcription factor (ATF)-2.

25 ivity was enhanced by a wild-type activating transcription factor (ATF-2), whereas a phosphorylation-

26 t the basic leucine zipper domain (b-ZIP) of transcription factor ATF-2 (also called CRE-BP1) can int

27 The transcription factor ATF-2, a p38 MAPK substrate, is pho

28 aling p38 pathway, which may activate target transcription factor ATF-2, which in turn induces PTEN e

29 The transcription factor ATF-2, which is phosphorylated and

30 amily, as assessed by phosphorylation of the transcription factor ATF-2.

31 on TNF-alpha-induced phosphorylation of the transcription factor ATF-2.

32 transcription through p38 and its downstream transcription factor ATF-2.

33 and Jun kinases and increased p53 and other transcription factors (ATF-2, ELK-1, CREB, AP-1).

34 The transcription factors ATF-2 and c-Jun are important for

35 ation, we demonstrated that a heterodimer of transcription factors ATF-2 and c-JUN is constitutively

36 ed protein kinases as well as the downstream transcription factors ATF-2 and c-Jun.

37 hibiting p38SAPK prevented activation of the transcription factors ATF-2 and CREB and significantly r

38 increase in the phosphorylated forms of the transcription factors ATF-2 and Elk-1.

39 ulate signal transduction pathways involving transcription factors ATF-2 and Jun repress apoCIII prom

40 (MAP) kinase activity and the binding of the transcription factors ATF-2 and Jun to the TNF-alpha cAM

41 The transcription factors ATF-2, c-jun, Egr-1, and Sp1 are a

42 In virus-infected cells the transcription factors ATF-2, c-Jun, interferon regulator

43 tains several putative binding sites for the transcription factors ATF-2, Ets-1, Egr-1 and SP1/SP3.

44 s assembly of an enhanceosome containing the transcription factors ATF-2/c-Jun, IRF-3/IRF-7, NF-kappa

45 transcription and reduced expression of the transcription factors, ATF-2 and c-Jun, which normally b

46 antly inhibited the expression of activating transcription factor (ATF) 3, a member of the ATF/cyclic

47 Activating transcription factor (ATF)3 regulates the expression of

48 es the first in vivo evidence for activating transcription factor (ATF)-3 binding to the proximal ASN

49 of the transcriptional repressor activating transcription factor (ATF-3) in a STAT1-dependent manner

50 (GEM) treatment upregulates SERPINB9 through transcription factor ATF-3.

51 t two-hybrid assay, we identified activating transcription factor (ATF) 4 as a potential Nrf2-interac

52 e identified basic leucine zipper activating transcription factor (ATF) 4 as one of the HRG-inducible

53 tor 2, and increased synthesis of activating transcription factor (ATF) 4 by a translational control

54 CHOP as an interacting partner of activating transcription factor (ATF) 4 in a yeast two-hybrid scree

55 Activating transcription factor (ATF) 4 is a ubiquitous basic leuci

56 2alpha (eIF2alpha)-like ER kinase/activation transcription factor (ATF) 4 pathway.

57 nslation of a "master regulator," activating transcription factor (ATF) 4, and ultimately, to regulat

58 s of phosphorylated eIF2alpha and activating transcription factor (ATF) 4, which is essential for Fgf

59 N gene expression, interacts with activating transcription factor (ATF)4, a key component of the inte

60 d the CRE as a complex containing activating transcription factor (ATF)-4 and CCAAT enhancer-binding

61 ) and serine biosynthesis via the downstream transcription factor ATF-4.

62 resulting in preferential translation of the transcription factor ATF-4.

63 -regulates the translation and expression of transcription factor ATF-4.

64 response, resulting in the induction of the transcription factor ATF-4.

65 ARalpha), activates expression of Activating Transcription Factor (ATF) 5 and ATF4, two major UPR(mt)

66 eased by the ER stress modulator, activating transcription factor (ATF)6, which can induce genes that

67 histone acetyltransferase CBP-1/p300 or the transcription factor ATF-8, a member of the bZIP family

68 -regulated oxidative stress pathways and the transcription factors ATF (activating transcription fact

69 vegetalizing (beta-catenin) and animalizing transcription factor (ATF) activities and their region o

70 ding sites for sequence-dependent activating transcription factor (ATF)-adenosine 3',5'-monophosphate

71 Treg cell induction, Setdb1 is recruited by transcription factor ATF and altered histone methylation

72 liberate NF-kappaB also activate activating transcription factor (ATF) and activator protein 1 (AP-1

73 p1, glucocorticoid receptor (GR), activating transcription factor (ATF) and cAMP response element-bin

74 by using a library of zinc finger artificial transcription factors (ATFs) and functional screening of

75 Artificial transcription factors (ATFs) and genomic nucleases based

76 Bacterial allosteric transcription factors (aTFs) are a major class of regula

77 ulatory proteins (DRPs), in which artificial transcription factors (ATFs) are fused to cell-penetrati

78 Artificial transcription factors (ATFs) are potent synthetic biolog

79 Artificial transcription factors (ATFs) are precision-tailored mole

80 Point-of-use diagnostics based on allosteric transcription factors (aTFs) are promising tools for env

81 nd a region containing a consensus activated transcription factor (ATF) binding site.

82 In this paper, we identified an activating transcription factor (ATF)/cAMP-responsive element-bindi

83 l as transcription from the C/EBP-activating transcription factor (ATF) composite motif in the GADD15

84 The structure of this artificial transcription factor (ATF) consists of three parts: (i)

85 Two activating transcription factor (ATF)/CREB family members, CREB-1 a

86 heart and somites via one or more activating transcription factor (ATF)/cyclic AMP response element b

87 get for binding of members of the activating transcription factor (ATF)/cyclic AMP response element b

88 downstream of a binding site for activating transcription factor (ATF)/cyclic AMP response element b

89 downstream components, including activating transcription factor (ATF)/cyclic AMP-responsive element

90 role of different members of the activating transcription factor (ATF) family in survival of diffuse

91 s are dimers of JUN, FOS, MAF and activating transcription factor (ATF) family proteins characterized

92 transcription factor of the CREB/activating transcription factor (ATF) family, increases in expressi

93 g proteins include members of the activating transcription factor (ATF) family.

94 Bacterial allosteric transcription factors (aTFs) have evolved to sense and r

95 Allosteric transcription factors (aTFs) have proven widely applicab

96 Although the name Activating Transcription Factor (ATF) implies that they are transcr

97 ger synthetic zinc finger protein artificial transcription factors (ATFs) in an epidermoid squamous c

98 osarcoma (c-Maf), Bcl6, basic leucine zipper transcription factor ATF-like (Batf), and IL-21, and STA

99 sumption, the number of basic leucine zipper transcription factor ATF-like 3 ( Batf3 )-dependent conv

100 microglia, whereas the Basic leucine zipper transcription factor ATF-like 3 (Batf3) acts downstream

101 The basic leucine zipper transcription factor ATF-like 3 (BATF3) is required for

102 Here, we show that the basic leucine zipper transcription factor ATF-like, Batf is important for IL-

103 Mice without the basic leucine zipper transcription factor, ATF-like (BATF) gene (Batf(-/-)) l

104 The AP-1 factor basic leucine zipper transcription factor, ATF-like (BATF) is important for C

105 ogram includes upregulation of basic leucine transcription factor, ATF-like (BATF), a transcription f

106 Bcl6 target genes Batf (basic leucine zipper transcription factor, ATF-like) and Bcl6, in part throug

107 related inversely BATF (basic leucine zipper transcription factor, ATF-like) and IRF4 (interferon-reg

108 report here that BATF (basic leucine zipper transcription factor, ATF-like), an AP-1 protein family

109 We have constructed artificial transcription factors (ATFs) made of six zinc-finger (ZF

110 e basic leucine zipper containing activating transcription factors (ATFs) modulates the expression of

111 tains a sequence homologous to an activating transcription factor (ATF) motif, and ATF-1 is a major c

112 relate Tax activation of the CREB/activating transcription factor (ATF) or NFkappaB/Rel transcription

113 Ligand-responsive allosteric transcription factors (aTF) play a vital role in genetic

114 Allosteric transcription factors (aTF) regulate gene expression thr

115 ecule detection platform based on allosteric transcription factor (aTF)-regulated expression of a clu

116 Here, we demonstrate that an artificial transcription factor (ATF-S1K) can silence Ube3a-ATS in

117 se element binding protein (CREB)/activating transcription factor (ATF) site overlapping a CpG island

118 y appeared to be mediated via the activating transcription factor (ATF) site, because mutation of thi

119 to its cAMP-response element (CRE)/activated transcription factor (ATF) site.

120 te is adjacent to identified CREB/activating transcription factor (ATF) sites, present in the Igamma1

121 We engineered two artificial transcription factors (ATFs) that contain Cys(2)His(2) z

122 We used bacterial allosteric transcription factors (aTFs) that control gene expressio

123 to identify and isolate bacterial allosteric transcription factors (aTFs) that recognize a target ana

124 rch tools and therapeutic agents, artificial transcription factors (ATFs) that up-regulate transcript

125 d a sequence-specific zinc finger artificial transcription factor (ATF) to up-regulate the Maspin pro

126 DMS) of four homologous bacterial allosteric transcription factors (aTFs) to identify hotspots and bu

127 an emerging technology that uses artificial transcription factors (aTFs) to regulate expression of a