ライフサイエンスコーパス: transcription machinery

1 tazoan splicing transpires distally from the transcription machinery.

2 es influence promoter activity and the cbbLS transcription machinery.

3 e target genes to limit accessibility to the transcription machinery.

4 etween transcription factors and the general transcription machinery.

5 uclear compartmentalization of the genes and transcription machinery.

6 is not a core component of the mitochondrial transcription machinery.

7 mechanism that permits access to DNA by the transcription machinery.

8 ole as a core component of the mitochondrial transcription machinery.

9 pecific initiation by the core mitochondrial transcription machinery.

10 ermore is uniquely associated with the basal transcription machinery.

11 from the NPR1 signaling node to the general transcription machinery.

12 ding proteins, chromatin remodelers, and the transcription machinery.

13 e protein was not evident in the Pol I basal transcription machinery.

14 ical utilization and better recycling of the transcription machinery.

15 ption activity after initial assembly of the transcription machinery.

16 neous binding of the large RNA polymerase II transcription machinery.

17 als elicit distinct modes of assembly of the transcription machinery.

18 ct sequence-specific activators to the basal transcription machinery.

19 cated as a component of the RNA polymerase I transcription machinery.

20 DNA access by transcription factors and the transcription machinery.

21 to directly inhibit activation of the basal transcription machinery.

22 e transcriptional activators and the general transcription machinery.

23 r chromatin modifying complexes or the basal transcription machinery.

24 omatin structure and regulation of the basal transcription machinery.

25 he sigma(54) factor makes with the bacterial transcription machinery.

26 factors, chromatin regulatory proteins, and transcription machinery.

27 factor between NF-kappaB, CBP, and the basal transcription machinery.

28 quences by creating steric obstacles for the transcription machinery.

29 nto open chromatin that is accessible to the transcription machinery.

30 get genes, chromatin, accessory proteins and transcription machinery.

31 chromatin remodeling and recruitment of the transcription machinery.

32 irally encoded proteins that hijack the host transcription machinery.

33 metazoans is Cdk7, which is also part of the transcription machinery.

34 t depends on components of the Pol I general transcription machinery.

35 as a conduit between activators and the core transcription machinery.

36 may lead to species specificity of the rDNA transcription machinery.

37 tors that enhance their binding to the basal transcription machinery.

38 direct physical interaction with the head-on transcription machinery.

39 moter, suggesting this virus encodes its own transcription machinery.

40 unction of RNA polymerase II and the general transcription machinery.

41 rDNA looping that promotes recycling of the transcription machinery.

42 romatin remodeling and assembly of the pol I transcription machinery.

43 TA-binding protein, and TFIIB of the general transcription machinery.

44 interact with TAFII68, a member of the basal transcription machinery.

45 deacetylation and interaction with the basal transcription machinery.

46 ly, whereas Mot1 promotes disassembly of the transcription machinery.

47 unctional relationship between Dbp5p and the transcription machinery.

48 ctivities of components of the general/basal transcription machinery.

49 nction properly in the context of the oocyte transcription machinery.

50 mechanisms of RNAP and the evolution of the transcription machinery.

51 to other regulatory factors and the general transcription machinery.

52 ation by preventing recruitment of the basal transcription machinery.

53 in the interaction between GR and the basal transcription machinery.

54 Sp1/Sp3 complex, and its impact on the basal transcription machinery.

55 between transcription factors and the basal transcription machinery.

56 chanism involving interaction with the basal transcription machinery.

57 t promoter regions to regulate access by the transcription machinery.

58 ted through inhibition of cEBPbeta-NFkB-AP-1 transcription machinery.

59 dies as sites for preassembly of the nuclear transcription machinery.

60 mplex is recruited by the RNA polymerase III transcription machinery.

61 cruitment of RNA polymerase II and the basal transcription machinery.

62 P-Jkappa, Notch IC, and MAML1 on the general transcription machinery.

63 conveys regulatory information to the basal transcription machinery.

64 iption initiation by the human mitochondrial transcription machinery.

65 expression of nuclear genes for the plastid transcription machinery.

66 activity by controlling DNA accessibility to transcription machinery.

67 gulatory mechanisms coevolved with the basal transcription machinery.

68 between the upstream activators and general transcription machinery.

69 RSAM1 may aberrantly affect the formation of transcription machinery.

70 associated adaptor complex accesses the core transcription machinery.

71 thus providing a direct link to the general transcription machinery.

72 rial DNA copy number can be regulated by the transcription machinery.

73 te DNA's flexibility and the assembly of the transcription machinery.

74 modeling factors and interact with the basal transcription machinery.

75 omplex that nucleates formation of the basal transcription machinery.

76 n factors and the RNA polymerase II (RNAPII) transcription machinery.

77 inding transcription factors and the general transcription machinery.

78 ), chromatin regulators (CRs), and the basal transcription machinery.

79 ugh the head and middle modules to the basal transcription machinery.

80 n eukaryotic Pol I, II, and III and archaeal transcription machineries.

81 s to link the H2B ubiquitylation and general transcription machineries.

82 able to replicate its RNA by use of cellular transcription machineries.

83 ctory to recombination and RNA polymerase II transcription machineries.

84 eplication complex with the Pol I and Pol II transcription machineries.

85 s that can arise between the replication and transcription machineries.

86 ndent encounters between DNA replication and transcription machineries.

87 ld for interactions between the splicing and transcription machineries.

88 are they non-functional byproducts of nearby transcription machinery?

89 ent recruitment of hBRE1-hRAD6 to the Pol II transcription machinery; (4) that H2B ubiquitylation per

90 higher plants is dependent on two different transcription machineries, a plastid-encoded bacterial-t

91 oops are tethered to "factories" through the transcription machinery-a polymerase (active or inactive

92 Elucidating the mechanisms by which the transcription machinery accesses promoters in their chro

93 In yeast, Paf1 is part of the transcription machinery, acting as a docking protein in

94 est that Ku also interacts with the cellular transcription machinery, although the mechanism and sign

95 histone tails and components of the general transcription machinery, although the relative contribut

96 The distribution of the transcription machinery among different sub-nuclear doma

97 anscriptional activation by recruiting basal transcription machinery and acetylating histones.

98 tely require chromatin to assemble the basal transcription machinery and activate transcription.

99 d/or various components of the general/basal transcription machinery and are essential for regulated

100 trinsic DNA specificity and suggest that the transcription machinery and associated promoter accessib

101 S. pombe, it was accepted by the endogenous transcription machinery and caused initiation to be rest

102 A has a key role in the pre-configuration of transcription machinery and chromatin for genome activat

103 redominant organizational theme by which the transcription machinery and chromatin regulators are pos

104 the proteasome directly influences both the transcription machinery and chromatin structure, factors

105 the highly medically-relevant mycobacterial transcription machinery and define HelD as a clearing fa

106 o study the localization and dynamics of the transcription machinery and DNA in live bacterial cells,

107 coactivators to communicate with the general transcription machinery and establish transcriptional pr

108 a molecular link between upregulation of the transcription machinery and genomic instability in cance

109 operative binding of these components of the transcription machinery and indicating that it is the PI

110 BP) is a central component of the eukaryotic transcription machinery and is subjected to both positiv

111 hanisms behind assembly of the mitochondrial transcription machinery and its regulation are poorly un

112 cupancy of the Methanocaldococcus jannaschii transcription machinery and its transcriptome.

113 th ribosomal DNA clusters recruits the pol I transcription machinery and maintains these loci in a tr

114 ween the NPR1 signaling node and the general transcription machinery and may relay signals from both

115 NAP is a critical component of the S. aureus transcription machinery and plays an important role duri

116 e of 19S ATPases in the assembly of CIITApIV transcription machinery and provide additional insight i

117 The basal transcription machinery and regulatory components are dy

118 ting tissue-selective functions of the basal transcription machinery and reveal intricate networks of

119 of lignin biosynthesis, and suggest that the transcription machinery and signalling pathways respondi

120 ransduction of cellular signals to the basal transcription machinery and that one of these signals co

121 isms requires spatiotemporal coordination of transcription machinery and the transcription factors at

122 t a model in which TREX is recruited via the transcription machinery and then Yra1p and Sub2p are tra

123 ors that are sufficient to recruit the basal transcription machinery and therefore activate transcrip

124 timately modulates the action of the general transcription machinery and therefore limits the possibi

125 demonstrate a direct connection between the transcription machinery and ubiquitin-mediated proteolys

126 ithin promoters of active genes to allow the transcription machinery and various transcription factor

127 the level of combined effects on the general transcription machinery and, in addition, a direct role

128 RNA aptamers compatible with the cell's own transcription machinery and, thus, expressable inside ce

129 fere with the progression of replication and transcription machineries, and hence threaten genomic in

130 transferase SETD2, a component of the active transcription machinery, and 'ejects' the elongation cor

131 ky O(6)-alkylguanines blocks GGR, stalls the transcription machinery, and diverts the damage to trans

132 purification of essential components of the transcription machinery, and identification and mechanis

133 condensin, which interacts with the Pol III transcription machinery, and that transcription levels o

134 ator complex that interacts with the general transcription machinery, and the highly regulated PGC-1a

135 collision between replication forks and the transcription machinery, and the persistence of RNA-DNA

136 reported that defined components of the host transcription machinery are recruited to human cytomegal

137 structure, composition and accessibility to transcription machinery are strictly and dynamically con

138 specific DNA binding factors and the general transcription machinery are unaffected by the status of

139 oncoding genome elements, and epigenetic and transcription machinery, are essential for establishing

140 nitiation of XCI, bridging Xist RNA with the transcription machinery-as well as with nucleosome remod

141 We derived comprehensive views of the transcription machineries assembled at estrogen-responsi

142 We infer cis-dependent perturbation of transcription machinery assembly by transcriptional inte

143 evel of continued transcription output after transcription machinery assembly.

144 The host cell transcription machinery associated with the specific IL-

145 e different targets within the basal pol III transcription machinery at different times during the ce

146 nd/or stability inhibits the assembly of the transcription machinery at normally quiescent promoters,

147 ators have been implicated in assembling the transcription machinery at particular enhancers, yet the

148 ether with RNA polymerase II, form the basal transcription machinery at the core promoter.

149 so discuss novel roles for the mitochondrial transcription machinery beyond transcription initiation,

150 In yeast the RNA pol III transcription machinery bound to tRNA genes function wit

151 between gene specific factors and the basal transcription machinery but little is known regarding th

152 re is not only a fundamental property of the transcription machinery, but it is emerging as an import

153 enrichment of Mediator and RNA polymerase II transcription machinery, but not that of LDTFs, MLL3/MLL

154 lted in effective recruitment of the general transcription machinery, but some reduction in histone m

155 single-stranded DNA (ssDNA) generated by the transcription machinery, but the detailed mechanism rema

156 NA for transcription factors and the general transcription machinery, but whether mammalian chromatin

157 mechanism by which E1A hijacks the cellular transcription machinery by competing with essential tran

158 pecific regulation of Mediator and the basal transcription machinery by HMGA1.

159 ription without interacting with the general transcription machinery by looping-out the intervening D

160 ion dynamics of eukaryotic RNA polymerase II transcription machinery by MAPKs, CTD kinases, and phosp

161 of 18S rDNA into HeLa nuclei show that pol I transcription machinery can be recruited to rDNA promote

162 Thus, the general transcription machinery can contribute to nucleosome rem

163 Conflicts between the replisome and transcription machinery can lead to interruption of DNA

164 TA element and the components of the general transcription machinery can lead to variations in the fo

165 iffering modes of its recognition by general transcription machinery can provide an additional layer

166 ng how the organization of chromatin and the transcription machinery co-evolve.

167 ncorporate greater mechanistic detail of the transcription machinery compared to existing models and

168 A polymerase II (Pol II), the major cellular transcription machinery component, is an important step

169 The core human mitochondrial transcription machinery comprises a single subunit bacte

170 ances in understanding the RNA polymerase II transcription machinery, conserved coactivator complexes

171 ins to transmit the activating signal to the transcription machinery, depending on whether it is boun

172 We report a mechanism through which the transcription machinery directly controls topoisomerase

173 upstream of the HO gene is induced, and the transcription machinery displaces promoter-bound SBF, pr

174 (c) identification of a new component of the transcription machinery, DksA, that is absolutely requir

175 ditions, occupancy of a large portion of the transcription machinery does not.

176 h TFAM is absolutely required to recruit the transcription machinery during initiation of transcripti

177 and lineage-restricted factors and the basic transcription machinery during lymphocyte differentiatio

178 interactions between the major components of transcription machinery during the early stages of the t

179 e-scale rearrangements on the surface of the transcription machinery during the transition from trans

180 Global transcription machinery engineering (gTME) is an approac

181 ysis of Library Enrichments (SCALEs), global transcription machinery engineering (gTME), and gene-dis

182 nit diversity and specificity in the general transcription machinery for orchestrating multicellular

183 The basal eukaryotic transcription machinery for protein coding genes is high

184 FIIF efficiently recruits FCP1 to the pol II transcription machinery for recycling of the polymerase.

185 on with novel SUMO substrates found in basal transcription machinery for RNA polymerases I, II, and I

186 Transcription machinery from a variety of organisms show

187 ulatory effects on its cognate eukaryal-type transcription machinery from an upstream activating regi

188 that PcG proteins do not merely prohibit all transcription machinery from binding the template but in

189 , chromatin modifying enzymes, and the basal transcription machinery govern cellular differentiation,

190 han a simple chromosome-wide separation from transcription machinery, governs gene silencing over the

191 Recently, the core human mitochondrial transcription machinery has been defined, comprising a b

192 ned state around a certain locus so that the transcription machinery has continuous access to DNA.

193 s detected in S regions, suggesting that the transcription machinery has paused and stalling is aboli

194 at each round of rDNA replication, the Pol I transcription machinery has to deal with nucleosomal bar

195 Alternate forms of the general transcription machinery have been described in several t

196 early demonstrated, the contributions of the transcription machinery have not been firmly established

197 ese two strands are synthesized in different transcription machineries in the cells, but the nature o

198 factors TAFII250 and TFIIB assemble into the transcription machinery in a stress- and promoter-specif

199 dered recruitment of components of the basal transcription machinery in concert with alterations in c

200 supports NS1 nuclear function to hijack host transcription machinery in favor of viral RNA synthesis,

201 Recent work has revealed that the transcription machinery in many bacteria diverges from t

202 rate that SWI/SNF influences the most robust transcription machinery in proliferating cells.

203 The results suggest that the LTR-assembled transcription machinery in synthesizing non-coding, LTR

204 nuclear PTEN, which by interacting with the transcription machinery in the context of chromatin exer

205 To understand the contribution of the transcription machinery in the disassembly of the +1 H2A

206 to degradation of transcription factors and transcription machinery in the nucleus.

207 eir associated activators, while the general transcription machinery including core promoter recognit

208 teractions with components of the U6 general transcription machinery, including SNAP(C) and TFIIIB.

209 nd represents a fundamental component of the transcription machinery, interacting with the RNA polyme

210 neries in the cells, but the nature of these transcription machineries is not clear.

211 oth prokaryotes and eukaryotes, and that the transcription machinery is a molecular tie.

212 ng stationary phase when the majority of the transcription machinery is bound by the RNA.

213 n profile, suggesting that the mitochondrial transcription machinery is coordinately regulated in res

214 Although the dynamics of transcription machinery is essential to genome regulatio

215 red and no ATF4 interaction with the general transcription machinery is necessary.

216 e role of components of the RNA polymerase I transcription machinery is paramount to understanding re

217 ssibility to DNA-binding factors and the RNA transcription machinery is regulated.

218 e show that the association of Spn1 with the transcription machinery is strongly dependent on its bin

219 inued transcription output after assembly of transcription machinery is unaffected by curcumin.

220 e chromatin structure that competes with the transcription machinery, leading to its silencing.

221 AC and tTAF cell type-specific chromatin and transcription machinery leads to loss of Polycomb and re

222 s support a model in which splicing recruits transcription machinery locally to influence TSS choice

223 ven O-GlcNAcylation of key components of the transcription machinery may epigenetically modulate gene

224 upstream of transcription start sites; (c). transcription machinery may hinder access of NER factors

225 ble of interacting with components of active transcription machinery, mimicking archetypal acidic act

226 ive and negative regulators with the general transcription machinery modulates transcription.

227 proteins revealed associations with cellular transcription machinery; modulators of transcription; co

228 We also find association of SDG8 with the transcription machinery, namely RNA polymerase II and th

229 atin remodeling complex, NURF, and the basal transcription machinery near the transcriptional start s

230 f RNA polymerase II (Pol II) and the general transcription machinery near the TSS.

231 We also show that Pax5 targets the basal transcription machinery of c-fms by interacting with a b

232 These proteins make up the replication and transcription machinery of MuV.

233 known about how archaeal viruses perturb the transcription machinery of their hosts.

234 ad-on encounters between the replication and transcription machineries on the lagging DNA strand can

235 FIID and assembles with POL II and the basal transcription machinery on promoters in vivo.

236 nd impeding the efficient recruitment of the transcription machinery on the promoter of an activated

237 and 3) direct interference with the general transcription machinery or activators.

238 domain that interacts specifically with the transcription machinery or nearby factors.

239 ositively depending upon whether the general transcription machinery or RNA polymerase III is prefere

240 by facilitating or obstructing the action of transcription machinery or the access to chromosomal DNA

241 s little effect on accessibility of SINEs to transcription machinery or their expression in vivo.

242 rnberg, on the structure and function of the transcription machinery; Peter Novick, on the regulation

243 ization of the genes, enhancer elements, and transcription machinery plays an essential role in tissu

244 ar phosphoprotein (P) component of the viral transcription machinery, preventing the synthesis of vir

245 ovide the first insights into how the Pol II transcription machinery processes the most abundant DNA

246 ncluding a critical component of the general transcription machinery proteins, the TATA box binding p

247 Saccharomyces cerevisiae) mitochondrial (mt) transcription machinery provide mechanistic understandin

248 actions between SMC complexes and elongating transcription machinery relevant from bacteria to higher

249 Collisions between replication and transcription machineries represent a significant source

250 act that eukaryotes with well-developed gene transcription machinery require transcription factor fle

251 Recent studies of the three eukaryotic transcription machineries revealed that all initiation c

252 RNA polymerase (RNAP), the transcription machinery, shows dynamic binding across th

253 orrelate with the RNA polymerase II, Pol II, transcription machinery significantly better than with E

254 Mediator is required for recruitment of the transcription machinery subsequent to chromatin remodeli

255 mber of promoters have key components of the transcription machinery, such as TATA-binding protein (T

256 en Xeed and a component of the Xenopus basal transcription machinery, TAF(II)32.

257 ch region bound to components of the general transcription machinery [TATA-binding protein (TBP), TAF

258 eractions with one or more components of the transcription machinery, termed the "target." The identi

259 protein 1], Fhl1, Ifh1, Sfp1, and Hmo1), the transcription machinery (TFIIB, TFIID, and RNA polymeras

260 her member of the RNA polymerase III general transcription machinery, TFIIIB.

261 omponent of the eukaryotic RNA polymerase II transcription machinery that binds to TATA boxes located

262 enome of coronaviruses encodes a replication/transcription machinery that is unusually complex and co

263 nsferase p300, and components of the general transcription machinery that, by themselves, suffice for

264 The activity of the bacterial transcription machinery, the RNA polymerase (RNAP), is o

265 tionally obligatory subunit of the bacterial transcription machinery, the RNA polymerase.

266 othecin, or by collision with replication or transcription machinery, thereby causing protein-linked

267 ptional activators and the RNA polymerase II transcription machinery; therefore, our data suggest tha

268 nveys its stimulatory effects on its cognate transcription machinery through direct recruitment of th

269 crest cells, potentially linking the global transcription machinery through Med23 to the etiology an

270 RNA synthesis occurs in the Pol I and Pol II transcription machineries, thus extending the capability

271 ls was a prerequisite for targeting the mRNA transcription machinery, thus conferring cancer selectiv

272 hought to recruit limiting components of the transcription machinery to a core promoter.

273 e minimal DNA region that recruits the basal transcription machinery to direct efficient and accurate

274 s in part by facilitating recruitment of the transcription machinery to DNA.

275 tion factor (pTEFb) to the RNA polymerase II transcription machinery to enable an efficient HIV-1 RNA

276 ow phages fine-tune the activity of the host transcription machinery to ensure both successful and ef

277 factor TFIID facilitates recruitment of the transcription machinery to gene promoters and regulates

278 gets two critical components of the myogenic transcription machinery to inhibit terminal differentiat

279 hey interact with each other and the general transcription machinery to maintain on or off states of

280 ons that mediate aberrant recruitment of the transcription machinery to MLL target genes.

281 her a protein effector can interact with the transcription machinery to prematurely terminate transcr

282 nt of the transcriptional regulators and the transcription machinery to promoter chromatin is coordin

283 med the remarkable capability of the reverse transcription machinery to recognize short regions of se

284 iption factors and components of the general transcription machinery to regulatory regions upstream o

285 associates with the RNA polymerase I (Pol I) transcription machinery to suppress rRNA gene transcript

286 Recruitment of transcription machinery to target promoters for aberrant

287 enetic mark that promotes the recruitment of transcription machinery to the Cd8 enhancers.

288 ed through either coordinated recruitment of transcription machinery to the gene promoter or regulate

289 iption in DCs by prolonging binding of basic transcription machinery to the IFN promoters, thereby pl

290 le-specific activator MyoD recruits the core transcription machinery to the promoter of a key regulat

291 ruit and/or stabilize binding of the general transcription machinery to the proximal promoter of thei

292 Met4 and competes with binding of the basal transcription machinery to the same region.

293 expression by blocking access of the general transcription machinery to the underlying DNA sequences.

294 nto a mechanism by which RECQ5 regulates the transcription machinery via its dynamic interaction with

295 oA AD transmits its activating signal to the transcription machinery, we defined specific subregions,

296 sions that occur between the replication and transcription machineries when genes are encoded on the

297 via RNA polymerase II, bridging the general transcription machinery with gene-specific regulatory pr

298 t of the general RNA polymerase II (RNAP II) transcription machinery with intrinsic sequence-specific

299 implementations of the interaction of basal transcription machinery with promoter DNA, depending on

300 by the differences in the interaction of the transcription machinery with the different promoters.