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1 ain containing a basic leucine zipper (bZIP) transcriptional activator.
2 Saccharomyces cerevisiae using a dCas9-based transcriptional activator.
3 machinery and we demonstrate Psi is a potent transcriptional activator.
4 One of these genes, mga2, is a putative transcriptional activator.
5 states depending on the presence of a strong transcriptional activator.
6 on was induced using a novel dead Cas9-VP160 transcriptional activator.
7 vide evidence that it may also function as a transcriptional activator.
8 n 3 (STAT3), a previously unidentified EDNRB transcriptional activator.
9 rs, ARF34 (AUXIN RESPONSE FACTOR 34) acts as transcriptional activator.
10 asm and the nucleus, where it functions as a transcriptional activator.
11 pment and differentiation, is a DPE-specific transcriptional activator.
12 neural patterning activities by acting as a transcriptional activator.
13 says suggested that PtrMYB152 functions as a transcriptional activator.
14 ted, indicating that PRMT5 can also act as a transcriptional activator.
15 s and acted evidently as a high hierarchical transcriptional activator.
16 INPs by repressing genes encoding neuroblast transcriptional activators.
17 ation domain contained within the CRY2-fused transcriptional activators.
18 he disruption of motifs recognized by strong transcriptional activators.
19 discovery of new cellular binding targets of transcriptional activators.
20 A (PrfA), a member of the Crp/Fnr family of transcriptional activators.
21 I repression by processing GLI proteins into transcriptional activators.
22 ous genes using engineered CRISPR/Cas9-based transcriptional activators.
23 udies of a subgroup of ARFs that function as transcriptional activators.
24 distal enhancers by specific complements of transcriptional activators.
25 0) and TCP22 proteins act as LWD-interacting transcriptional activators.
26 d mCdx4) are also preferential core promoter transcriptional activators.
27 d levels, balancing the inductive effects of transcriptional activators.
28 Shh and that Eya1/Six1 together regulate Gli transcriptional activators.
29 silent even in the presence of trans-acting transcriptional activators.
30 d NRF-1 transcription factors and TALE-based transcriptional activators.
31 SNAI3) and depleted of the binding sites of transcriptional activators.
32 achinery, eliminating the need for exogenous transcriptional activators.
33 RNA), which abrogates the function of CRISPR-transcriptional activators.
34 ide morphological cues that regulate certain transcriptional activators.
35 interconnected cascades of signal-responsive transcriptional activators.
37 ression and cytokine promoter binding of the transcriptional activators activating transcription fact
38 ve detection of intracellular xenobiotics by transcriptional activators, activating expression of mul
40 virus) encode an AL2 protein that is both a transcriptional activator and a silencing suppressor.
41 s fused to either a fluorescent protein or a transcriptional activator and is destabilized by mutatio
42 bium japonicum Irr is a conditionally stable transcriptional activator and repressor that accumulates
43 ur findings show that HDAC3 is a dichotomous transcriptional activator and repressor, with a non-cano
45 al activity of GLI1, a Hedgehog (Hh) pathway transcriptional activator and self-renewal agonist, and
47 lecular analyses showed that GRHL2 acts as a transcriptional activator and strongly associates with h
48 lls, we show that Xrn1 functions mainly as a transcriptional activator and that its disruption manife
49 uited to gene promoters by sequence-specific transcriptional activators and by chromatin modification
51 feedback loop (TTFL) composed of CLOCK-BMAL1 transcriptional activators and CRY-PER transcriptional r
52 subsets of the immune system, by controlling transcriptional activators and downstream cytokines, to
53 pectively regulate Zeb1, a repressor of Gnrh transcriptional activators and Gnrh itself, and Cebpb, a
54 is minimal Cas9 to rationally design compact transcriptional activators and inducible nucleases, to f
55 and mechanistic characterization of various transcriptional activators and repressors and include st
56 e averaging effect that arises when multiple transcriptional activators and repressors are accommodat
58 ectors, which target phytohormone receptors, transcriptional activators and repressors, and other com
59 and Twist2 coordinate the regulation of both transcriptional activators and repressors, thereby media
62 to existing models, where Rgg2 proteins are transcriptional activators and Rgg3 proteins are transcr
63 Recent work highlights the central role of transcriptional activators and suggests that these facto
64 ctions between basic helix-loop-helix (bHLH) transcriptional activators and the transcriptional repre
65 protein-protein interaction networks between transcriptional activators and transcriptional coactivat
66 ke protein-1 (BMAL1) heterodimer acts as the transcriptional activator, and Cryptochrome (CRY) and Pe
67 e proteolysis of Fra and Fra's function as a transcriptional activator are required for its ability t
68 ssing recombinases, reporters, and inducible transcriptional activators are key for many genetic stud
69 hich revealed prevalent point mutations in a transcriptional activator (Aro80) that is responsible fo
70 ess is encoded by many binding sites for the transcriptional activator Arrowhead and that, during evo
71 at selective deletion of the circadian clock transcriptional activator aryl hydrocarbon receptor nucl
72 ent paradox of RNA-mediated stabilization of transcriptional activators at enhancers with a repressiv
73 romoter association of the stress-responsive transcriptional activator Atf1 at the sites of transcrip
75 f the sigma(54) family must be acted on by a transcriptional activator before DNA opening and initiat
76 y the scaffold protein Axin, targets the key transcriptional activator beta-catenin for proteolysis.
80 l shutdown, nucleosome invasion, and reduced transcriptional activator binding required chromatin rem
81 ysine acetyltransferase TIP60 acetylates the transcriptional activator BMAL1 leading to recruitment o
82 nslation feedback loops composed of positive transcriptional activators (BMAL1 and CLOCK) and negativ
83 the recycling of RNAP, delta functions as a transcriptional activator by binding to an A-rich sequen
86 The new studies with Zap1 highlight how a transcriptional activator can facilitate decreased prote
87 domain fusion proteins to serve as chimeric transcriptional activators challenge use of this approac
88 transcriptional feedback loop featuring the transcriptional activators circadian locomotor output cy
89 k loops, which balance the activities of the transcriptional activators CLOCK (circadian locomotor ou
90 epresses expression of the gene encoding the transcriptional activator, CLOCK (CLK), and may also aff
91 set of lytic viral proteins assembles into a transcriptional activator complex to induce expression o
93 ) signaling, together with broadly expressed transcriptional activators, concurrently activates the g
94 H3K27me3 levels, while it switches EZH2 to a transcriptional activator, conferring higher proliferati
96 are antagonized by three different types of transcriptional activators: CREB/ATF-type Atf1, C(2)H(2)
97 s of S. pyogenes Deletion of the QS system's transcriptional activator (Deltargg2) dramatically dimin
98 nserved lncRNA, increases the association of transcriptional activators (DLX homeodomain proteins) wi
99 , which may provide effective treatments for transcriptional activator-driven malignancies and diseas
100 g the phosphorylation of their heterodimeric transcriptional activators (e.g., White Collar-1 [WC-1]-
101 o repressed c-Myc transcription by targeting transcriptional activator E2f1 and coactivator Tfdp2, as
102 e used to study the contribution of the T3SS transcriptional activator ExsA to epithelial traversal.
107 ach evolved strain has a point mutation in a transcriptional activator for xylose catabolic operons,
112 A-binding domain found in the LuxR family of transcriptional activators, functions as an essential ma
113 first stages of embryogenesis requires that transcriptional activators gain access to the genome and
114 nsgenic method in combination with the yeast transcriptional activator gal4 protein/upstream activati
116 s a multi-zinc finger protein that binds the transcriptional activator GATA4 and modulates GATA4-medi
117 sion of the genBA operon is regulated by the transcriptional activator GenR, which is encoded by the
118 TCH/SMO causes an increase in the downstream transcriptional activator GLI1 and a decrease in the GLI
120 These data demonstrate that Cas9-derived transcriptional activators have the potential to be used
123 ci and has no sequence similarity with known transcriptional activators, here we used Rosetta to gene
125 cids were shown to require the invasion gene transcriptional activator hilD and to function independe
129 we show that an interaction between the RPG transcriptional activator Ifh1 and the rRNA processing f
131 S (MuDPIT) analysis, we can trap the PPIs of transcriptional activators in a cellular setting and ide
132 enome-wide effects of TALE- and CRISPR-based transcriptional activators in human cells using ChIP-seq
133 after associating with the core loops of the transcriptional activators in their ATP state and that t
135 sts, we report here variants of the Q-system transcriptional activator, including QF2, for driving st
136 and demonstrate that TBX5, long considered a transcriptional activator, interacts biochemically and g
137 the yeast Saccharomyces cerevisiae, the Zap1 transcriptional activator is a central player in this pr
138 v2(ci32Gt) gene trap line, in which the Gal4 transcriptional activator is integrated into the etv2 ge
139 meostasis as controlled by the PGC family of transcriptional activators is required for angiogenic re
140 uman ILC2 cells in a manner dependent on the transcriptional activator ISGF3 that led to altered cyto
141 receptor 1 (S1PR1) and its critical upstream transcriptional activator Kruppel-like factor 2 (KLF2).
142 ese effects are coordinated, in part, by the transcriptional activator Kruppel-like factor-6 (Klf6).
143 y, we compared the protein levels of a MAO A-transcriptional activator, Kruppel-like factor 11 (KLF11
144 inhibited miR-210 expression by repressing a transcriptional activator, Kruppel-like factor-4 (KLF4).
146 eases and followed by zinc finger nucleases, transcriptional activator-like effector nucleases and, m
147 ome-editing platforms: zinc-finger proteins, transcriptional activator-like effectors and clustered r
148 f these syntelogs in the context of positive transcriptional activators may help guide attempts to al
149 ucible factors (HIFs), a family of essential transcriptional activators mediating the metazoan hypoxi
150 Using embryonic stem cell lines lacking the transcriptional activator MOZ and the polycomb-family re
151 men development and acting downstream of the transcriptional activator MS1 (MALE STERILITY 1), which
152 Contrary to the expected role of CarD as a transcriptional activator, mutation of CarD led to both
153 up-regulation of the smooth muscle-specific transcriptional activator myocardin at mRNA and protein
157 n lowers expression levels of the osteoclast transcriptional activator nuclear factor of activated T
158 r-activated receptor coactivator 1alpha, the transcriptional activators nuclear respiratory factor 1
159 of AtrA, which was initially described as a transcriptional activator of actinorhodin biosynthesis i
160 codes the aerobactin exporter, and LuxT is a transcriptional activator of aerobactin production.
161 tor gamma coactivator 1alpha (PGC-1alpha), a transcriptional activator of ALAS1, to affect hepatic he
162 nsposon insertion upstream of MdMYB1, a core transcriptional activator of anthocyanin biosynthesis, i
163 y and ChIP, KLF6 was established as a direct transcriptional activator of ATG7 and BECLIN1, but was d
165 s with published sites for SREBP-2, a master transcriptional activator of cholesterol biosynthesis.
170 Our data implicate PfAP2-G not only as a transcriptional activator of gametocyte genes, but also
172 ation and cellular invasion and was a direct transcriptional activator of genes that regulate CSC sel
173 sponsive element-binding protein (ChREBP), a transcriptional activator of glycolytic and lipogenic ge
174 ome proliferator-activated receptor alpha, a transcriptional activator of HMGCS2, is similarly down-r
178 criptional repressor, we found that it was a transcriptional activator of many key components of the
181 anistic studies demonstrated that MYSM1 is a transcriptional activator of Pax5, the repressors of pla
183 nscriptional repression on MYB46, encoding a transcriptional activator of PHENYLALANINE AMMONIA-LYASE
186 ed expression of genes regulated by the Zap1 transcriptional activator of Saccharomyces cerevisiae.
190 expression of constitutively active Sre1, a transcriptional activator of Tf2 elements, also alleviat
192 ung-directed gene transfer of TFEB, a master transcriptional activator of the autophagolysosomal syst
193 g a dominant-negative mutant of NF-YA, a key transcriptional activator of the Ccnb1 promoter, increas
194 emonstrate that Erg binds to and serves as a transcriptional activator of the G-protein-coupled recep
197 elective genetic ablation of RelA (p65), the transcriptional activator of the NF-kappaB pathway, reta
198 bits expression of ARID4B, while ARID4B is a transcriptional activator of the PI3K subunit genes PIK3
199 istems of vrs3 suggested that VRS3 acts as a transcriptional activator of the row-type genes VRS1 (Hv
200 omponent of E-cadherin junctions and as a co-transcriptional activator of the Wnt/beta-catenin signal
201 cytes IkappaBzeta was identified as a direct transcriptional activator of TNFalpha/IL-17A-inducible p
202 g the UCP1 promoter, we identify Zfp516 as a transcriptional activator of UCP1 as well as PGC1alpha,
203 rs of cardiac myocyte maturation, serving as transcriptional activators of adult cardiac metabolic an
204 of these, the conserved class A ARFs(5), are transcriptional activators of auxin-responsive target ge
206 FL) in which CLOCK and BMAL1 proteins act as transcriptional activators of Cryptochrome and Period ge
208 anthomonas species are DNA-sequence-specific transcriptional activators of host susceptibility genes
210 on FIL lines suggested that YABs function as transcriptional activators of JA-triggered responses.
211 R gamma coactivator 1 alpha (PGC1alpha), key transcriptional activators of mitochondrial biogenesis a
212 of our knowledge, TubZIP28 and TabZIP28 are transcriptional activators of starch synthesis first ide
213 and UC-514321 both directly target STAT3/5, transcriptional activators of TET1, and thus repress TET
215 M promoter and a reduction in the binding of transcriptional activators of the NF-kappaB pathway.
216 int-c confirmed that all three genes act as transcriptional activators of VRS1 and quantitative vari
217 is a zinc finger protein that functions as a transcriptional activator or repressor and participates
218 mprinting and gene expression by acting as a transcriptional activator or repressor of promoters and
221 Furthermore, Hth/Exd act in concert with the transcriptional activators Orthodenticle (Otd) and Spalt
223 have also shown that these TFs act either as transcriptional activators (OsPCF2, OsNIN-like4) or repr
225 a, which promotes histone methylation or the transcriptional activator, p65, which promotes histone a
228 Here we describe a mechanism whereby the transcriptional activator PhoP elicits expression of dis
229 of the LLO-encoding gene (hly) requires the transcriptional activator PrfA, and both hly and prfA ge
230 rome and de novo mutations in PURA, encoding transcriptional activator protein Pur-alpha, within the
234 that Arx plays a role as a context dependent transcriptional activator, rather than a primary inducer
235 n this study, we identified EIL1 as a second transcriptional activator regulating the sulfur-deficien
238 ntify a bromodomain protein that serves as a transcriptional activator required to coordinate express
240 essors (for example, the NCoR/SMRT complex), transcriptional activators, RNA, chromatin remodellers,
241 tivation from latency is the replication and transcriptional activator (RTA) encoded by the gene Orf5
243 gether with co-analysis of engagement of the transcriptional activator Sox2, indicate that repressors
245 hat ZNF143, the human homolog of the Xenopus transcriptional activator STAF, specifically binds to th
246 t gene transcription, despite the downstream transcriptional activator STAT1 being activated and boun
247 proteasomal degradation of the IFN-regulated transcriptional activator STAT2 from humans, but not mic
248 d binding sites for growth hormone-regulated transcriptional activators (STAT5, hepatocyte nuclear fa
249 ccharomyces cerevisiae, we tested whether co-transcriptional activator Sub1, recently identified as a
250 vities of the Yorkie/Scalloped and dJun/dFos transcriptional activators subsequently initiate alary m
252 myelination require the serial expression of transcriptional activators, such as Sox10, Oct6 (also ca
253 We define the conserved sigma(54)-dependent transcriptional activator TacA as a global regulator in
255 ics, we found that the balance between T-box transcriptional activator, Tbx5, and T-box transcription
260 he gabTD operon and its own gene (GabR) is a transcriptional activator that regulates transcription o
262 ption factor binding data identified several transcriptional activators that bind promoters with diff
263 in transcriptional regulation is imparted by transcriptional activators that bind to specific DNA seq
265 iferator-activated receptor alpha, which are transcriptional activators that mediate the fasting resp
266 of PRDM13 in repressing the activity of bHLH transcriptional activators that together are required to
267 ich the UPS affects transcription centers on transcriptional activators, the function of which can be
270 We hypothesized that recruitment of a strong transcriptional activator to an enhancer would be suffic
271 ivation (CRISPRa) to synthetically recruit a transcriptional activator to sites across large genomic
273 te multiple DNA breaks or to target multiple transcriptional activators to a single promoter for syne
274 n at the native locus through recruitment of transcriptional activators to individual gene promoters.
277 anscriptional repressor, but converts into a transcriptional activator upon activation of the canonic
278 that the noncanonical function of EZH2 as a transcriptional activator upregulates a set of genes inv
279 LA-A*0101 restricted peptide derived from co-transcriptional activator Vestigial-like 1 (VGLL1) as a
280 KLF1 and related family members function as transcriptional activators via recruitment of co-activat
281 dCas9) fused with four tandem repeats of the transcriptional activator VP16 (VP64) could be used for
282 ate that a dCas9-SunTag system utilizing the transcriptional activator VP64 drives robust and specifi
283 erpesviruses, a specialized complex of viral transcriptional activators (vTAs) coordinate to direct e
284 sviruses depends on a set of virally encoded transcriptional activators (vTAs) that hijack the host t
286 ncy program is controlled by the EBNA2 viral transcriptional activator, which targets promoters via R
287 level is low because, we show, the relevant transcriptional activators, which work from regulatory s
289 ing Yes-associated protein (YAP or YAP1) and Transcriptional Activator with a PDZ domain (TAZ or WW-d
290 ats deletion is Yes-associated protein (YAP)/transcriptional activator with PDZ-binding domain (TAZ)
291 ned unclear how beta-catenin's function as a transcriptional activator with TCF1 influences mESC fate
292 that in the yeast multidrug system, several transcriptional activators with distinguishable selectiv
294 th a PDZ domain (TAZ or WW-domain-containing transcriptional activator [WWTR1]), coactivators of the
296 that, in addition to its known function as a transcriptional activator, YAP functions as a transcript
299 ippo pathway leads to phosphorylation of the transcriptional activator yes-associated protein 1 (YAP1
300 genome activation are currently unknown, the transcriptional activator Zelda (ZLD) has been shown to