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1 e between upstream regulators and the Pol II transcriptional machinery.
2 stone acetyltransferase p300, and downstream transcriptional machinery.
3 rans-acting factors, chromatin, and the core transcriptional machinery.
4 ting that their interactions are mediated by transcriptional machinery.
5 litating assembly of other components of the transcriptional machinery.
6 , without affecting the recruitment of basal transcriptional machinery.
7 hich directly impacts the recruitment of the transcriptional machinery.
8 ts role as linker coactivator of Sp1 and the transcriptional machinery.
9 ls from transcription factors to the general transcriptional machinery.
10 ng and activating distinct components of the transcriptional machinery.
11 A through interaction with components of the transcriptional machinery.
12 c protein function communicates with nuclear transcriptional machinery.
13 a complex array of repressive and activating transcriptional machinery.
14 accessibility of underlying DNA sequences to transcriptional machinery.
15 fundamental part of the conserved eukaryotic transcriptional machinery.
16 ions between transcription factors and basal transcriptional machinery.
17 f the start site could influence activity of transcriptional machinery.
18 s of gonad-selective components of the basal transcriptional machinery.
19 tokine genes that allow accessibility to the transcriptional machinery.
20 n these pathways as the conduit to the basic transcriptional machinery.
21 essibility and leads to recruitment of basal transcriptional machinery.
22 nt that relays neural activity to the muscle transcriptional machinery.
23 bility to recruit specific components of the transcriptional machinery.
24 mass complexes associated with viral reverse transcriptional machinery.
25 n is still able to bind to its target in the transcriptional machinery.
26 3 and ERalpha binding and recruitment of the transcriptional machinery.
27 tween the yeast nuclear pore complex and the transcriptional machinery.
28 regions to transcription factors and to the transcriptional machinery.
29 ds to enhancement of elongation by the basal transcriptional machinery.
30 gene and seems to act as a regulator of the transcriptional machinery.
31 6 activation domain to the RNA polymerase II transcriptional machinery.
32 st that AID is recruited to S regions by the transcriptional machinery.
33 ncer-bound factors (activators) and the core transcriptional machinery.
34 the recruitment of coactivators or the basal transcriptional machinery.
35 ppropriate response to the RNA polymerase II transcriptional machinery.
36 ing interactions between Sp1 and the general transcriptional machinery.
37 tive signal that is transmitted to the basal transcriptional machinery.
38 ripts, perhaps through interactions with the transcriptional machinery.
39 w transmission of the hormonal signal to the transcriptional machinery.
40 hat Groucho may also interact with the basal transcriptional machinery.
41 possibly through specific recruitment of the transcriptional machinery.
42 tors, which keep the locus accessible to the transcriptional machinery.
43 nifying effects of activators on the general transcriptional machinery.
44 n strains bearing three modifications of the transcriptional machinery.
45 requirements for different components of the transcriptional machinery.
46 e activity directly to the RNA polymerase II transcriptional machinery.
47 subcomplex of the RNA polymerase II (PolII) transcriptional machinery.
48 cyclin-dependent kinase associated with the transcriptional machinery.
49 eir dependence on specific components of the transcriptional machinery.
50 ivates a previously unobserved target in the transcriptional machinery.
51 ell type-specific component of the mammalian transcriptional machinery.
52 omplex of Smad4 with components of the basic transcriptional machinery.
53 more than one mechanism of interaction with transcriptional machinery.
54 the interaction of these receptors with the transcriptional machinery.
55 iated coactivators and the RNA polymerase II transcriptional machinery.
56 al degeneracy in the highly complex metazoan transcriptional machinery.
57 interacting with coactivators and the basal transcriptional machinery.
58 t constantly required to give signals to the transcriptional machinery.
59 repression even in the presence of exogenous transcriptional machinery.
60 romatin modification and disabling the basal transcriptional machinery.
61 y of repair enzymes, and the fidelity of the transcriptional machinery.
62 g specific protein-protein contacts with the transcriptional machinery.
63 ning and a direct interaction with the basal transcriptional machinery.
64 ment of coactivators that interface with the transcriptional machinery.
65 essential for connecting STAT5 to the basal transcriptional machinery.
66 s an adapter between EBNA-2 and the cellular transcriptional machinery.
67 in the eukaryotic RNA polymerase II (RNAPII) transcriptional machinery.
68 accessibility of the nucleosomal DNA to the transcriptional machinery.
69 volved in interactions with other members of transcriptional machinery.
70 cts as a positive regulator for YAP-mediated transcriptional machinery.
71 ed chromatin regions prevent the activity of transcriptional machinery.
72 g upstream signaling pathways with the basal transcriptional machinery.
73 , which alter the kinetics and efficiency of transcriptional machinery.
74 es to the nucleus to initiate the downstream transcriptional machinery.
75 odifications, disrupting the assembly of the transcriptional machinery.
76 ced in the direction of transcription by the transcriptional machinery.
77 nes, acting broadly by removing stops on the transcriptional machinery.
78 ogeny in the absence of functional bacterial transcriptional machinery.
79 matin structure and to prevent access to the transcriptional machinery.
80 atalysing modifications of translational and transcriptional machinery.
81 roteins and defines DNA accessibility to the transcriptional machinery.
82 sponses via interactions with the endogenous transcriptional machinery.
83 romoter, where it perhaps interacts with the transcriptional machinery.
84 eactive oxygen species perturb the beta-cell transcriptional machinery.
85 not due to the simple steric blockage of the transcriptional machinery.
86 chromatin to make the promoter accessible to transcriptional machinery.
87 etic changes that facilitate assembly of the transcriptional machinery.
88 lates transcription through interaction with transcriptional machinery.
89 plex, and TAF1, an element of the core TFIID transcriptional machinery.
90 pecies are synthesized by different cellular transcriptional machineries.
91 igenetic modifications, which influences the transcriptional machinery aberrant in many human disease
92 ch is demonstrated to be sufficient to allow transcriptional machinery access to the HO promoter (in
93 e findings identify a surprising link in the transcriptional machinery across a large evolutionary di
94 er, IVMA provided a better definition of the transcriptional machinery activated during chronic and r
95 volved in mRNA processing associate with the transcriptional machinery and are in proximity to DNA.
96 recruiting other required components of the transcriptional machinery and as a histone acetyltransfe
97 ription factors with components of the basal transcriptional machinery and by augmenting the access o
98 a detailed analysis of the interplay between transcriptional machinery and chromatin on the RANTES pr
99 show that the human basal RNA polymerase II transcriptional machinery and core promoter are inherent
100 ional activators (vTAs) that hijack the host transcriptional machinery and direct it to a subset of v
101 rsisters are vulnerable to inhibition of the transcriptional machinery and especially to inhibition o
102 findings support a relationship between the transcriptional machinery and establishment of the repli
103 epigenetic modifications that influences the transcriptional machinery and is aberrant in many human
105 This renders the gene inaccessible to the transcriptional machinery and prevents induction of the
106 ives us insight into the interaction between transcriptional machinery and promoter elements, and may
107 t the promoter that contain both the general transcriptional machinery and promoter-specific factors.
108 AhR TAD makes multiple interactions with the transcriptional machinery and protein conformation plays
109 bunit composition of a core component of the transcriptional machinery and provide a paradigm for how
110 RG1 with Tax additionally recruits the basal transcriptional machinery and removes some of the core h
111 en increasingly implicated in control of the transcriptional machinery and serves as an intracellular
112 ting as bridging molecules between the basal transcriptional machinery and specific DNA-binding trans
113 esulting in recruitment of components of the transcriptional machinery and subsequent gene transcript
114 nactivates Rob by blocking its access to the transcriptional machinery and that inducers activate Rob
116 the ADs of p53, which binds both the general transcriptional machinery and the repressor protein MDM2
117 comprised of RNA Polymerase II (RNA Pol II) transcriptional machinery and we demonstrate Psi is a po
118 etail of how FOXP3 itself interacts with the transcriptional machinery and which components of the FO
119 concert, or perhaps in competition, with the transcriptional machinery and with chromatin modifiers t
120 NAs in enhancer-promoter looping, recruiting transcriptional machinery, and facilitating RNA polymera
121 gene promoter, affects the assembly of basal transcriptional machinery, and increases the recruitment
122 provides a link between beta-catenin and the transcriptional machinery, and possibly mediates the onc
123 the three-dimensional chromatin space, same transcriptional machinery, and similar Histone3 methylat
124 ctivator binds cooperatively to DNA with the transcriptional machinery, and the constitutively active
125 tructure that influence its accessibility by transcriptional machinery, and we are continuing to deve
128 ion initiation conformational changes in the transcriptional machinery are required to accommodate th
131 Results suggest that proteins of the plastid transcriptional machinery are specifically protected fro
132 potential to interact with the host DNA and transcriptional machinery as part of their mode of actio
134 ce suggest that it sees targets in the yeast transcriptional machinery at least partially distinct fr
135 These results show that IR interacts with transcriptional machinery at promoters and identify a pa
136 to target genes and links CLOCK-BMAL1 to the transcriptional machinery at target-gene promoters.
138 on, providing blueprints for the assembly of transcriptional machinery at transcription start sites (
139 es by interacting with some component of the transcriptional machinery binding to the promoter, an in
142 SWI/SNF is necessary for recruitment of RNA transcriptional machinery, but not for binding of transc
143 molecules such as Ca2+, H2O2, and SA affect transcriptional machinery by altering the expression and
144 during nutrient starvation directly targets transcriptional machinery by binding to the principal si
146 g to the promoter so that recruitment of the transcriptional machinery can be effected "at a distance
148 yeast, we investigated whether the RNAP III transcriptional machinery can recruit protein factors re
149 polymerases themselves and highlighting how transcriptional machinery can vary across bacterial gene
150 sical interaction with the RNA polymerase II transcriptional machinery (chromatin remodelling factors
151 l view of the functional relationships among transcriptional machinery, chromatin structure and gene
152 These changes in gene expression, related to transcriptional machinery, chromatin structure, and the
154 ecific transcription factors and the general transcriptional machinery contribute to the selectivity
155 thalamus, TTF1 remains active as part of the transcriptional machinery controlling female sexual deve
156 that degradation of the most active cellular transcriptional machinery couples cellular growth and pr
157 etal lung mesenchyme by interfering with the transcriptional machinery critical for lung morphogenesi
158 ractomes also involve signaling pathways and transcriptional machinery critical for survival and cell
160 dent kinase (CDK)-RB-E2F axis forms the core transcriptional machinery driving cell cycle progression
161 uggests the similarity between mycobacterial transcriptional machinery during growth in SCID and in b
162 n of plastid genes and genes for the plastid transcriptional machinery during leaf senescence Loss-of
164 ons, fewer promoters compete for the limited transcriptional machinery, effectively increasing the co
165 epts, including a recent approach for global transcriptional machinery engineering (gTME), which has
166 e, we demonstrate the combined use of global transcriptional machinery engineering and a high-through
169 se indicated that the subversion of the cell transcriptional machinery for the purpose of HIV-1 repli
170 sh that CK2 acts as a switch, converting the transcriptional machinery from functioning on one type o
171 tion mechanism of the HS2 enhancer-assembled transcriptional machinery from the enhancer through the
173 on activators (comprising a component of the transcriptional machinery fused to a DNA binding domain)
174 coded as methylated CpG dinucleotides to the transcriptional machinery, give rise to the debilitating
177 ing strains, but global engineering of their transcriptional machinery has produced better outcomes.
179 expression either by granting access to the transcriptional machinery in an open chromatin state or
180 ween transcriptional repressors and the core transcriptional machinery in bacteria and archaea are su
181 tial link between small RNA pathways and the transcriptional machinery in Caenorhabditis elegans.
182 Our results identify a role for essential transcriptional machinery in driving tumorigenesis and d
184 of the E2E promoter by the RNA polymerase II transcriptional machinery in infected cells limits trans
186 h coactivators and components of the general transcriptional machinery in order to regulate target ge
190 protein units ranging from split enzymes to transcriptional machinery in vitro, in yeast and in prim
191 itment of critical AR coregulators and basal transcriptional machinery, including NCOA3 and RNA polym
192 nal activators work by recruiting to DNA the transcriptional machinery, including protein complexes r
193 human BRCA1 tumor suppressor interacts with transcriptional machinery, including RNA polymerase II (
194 f such an experiment, the ordinary activator-transcriptional machinery interaction is replaced by a h
196 oming increasingly clear that the eukaryotic transcriptional machinery is adapted to exploit the pres
198 genes responsible for cell specification to transcriptional machinery is dependent on chromatin remo
200 A-bound activators and the RNA polymerase II transcriptional machinery is inhibited by the adenovirus
201 C or colder, at which temperature mammalian transcriptional machinery is largely inactive, thereby e
202 ng of the three factors is abrogated and the transcriptional machinery is no longer efficiently recru
204 epigenetic machinery in conjunction with the transcriptional machinery is responsible for maintaining
205 a critical component of the TGFbeta-induced transcriptional machinery, is shown here to be essential
206 ot only does TAZ couple phospho-Smads to the transcriptional machinery, it is also essential for thei
207 egment into the nuclear matrix and away from transcriptional machinery, leading to repression of basa
209 and Period2 (Per2) genes, components of the transcriptional machinery maintaining a clock rhythm.
210 hromatin modification and recruitment of the transcriptional machinery, many questions remain unanswe
211 ssociated protein, RbpA, suggesting that the transcriptional machinery may also be modified in respon
212 various components of the replicational and transcriptional machinery may be interfered with due to
213 findings suggest that mutations in the core transcriptional machinery may facilitate the evolution o
214 g RNA structure and recruitment of competing transcriptional machinery, may affect gene expression fr
215 horylation and ubiquitination enzymes, basal transcriptional machinery members, and RNA processing fa
217 oded (NEP and PEP) components of the plastid transcriptional machinery, mRNA and protein levels of so
218 nucleosomes; however, regulatory factors and transcriptional machinery must gain access to chromatin
219 signals and coordinate the activation of the transcriptional machinery necessary for differentiation
220 n among components of both chromatin and the transcriptional machinery, nucleosome depletion at promo
221 t apoptotic cells target the proinflammatory transcriptional machinery of macrophages with which they
224 by changes in the recruitment of the general transcriptional machinery or by post-POLR2A recruitment
225 ng to promoter elements and activating basal transcriptional machinery) or an indirect mechanism (via
226 ecific DNA binding activators to the general transcriptional machinery, or that help activators and t
227 nts, can be independently interpreted by the transcriptional machinery, possibly through successive e
228 ch lack genome segmentation and intra-capsid transcriptional machinery, predominantly display single-
229 cate that T(reg) cells use components of the transcriptional machinery, promoting a particular type o
230 interaction between splicing factors and the transcriptional machinery provides an intriguing link be
231 ayed by musicians (transcription factors and transcriptional machinery) reading the score encoded in
232 complexity and functional diversification of transcriptional machineries recognizing distal enhancers
233 ichia coli, bacteriophage T4 usurps the host transcriptional machinery, redirecting it to the express
235 n activator) gene; and reprogramming of host transcriptional machinery regulating a variety of cellul
236 during infection, HHV-8 reprograms the host transcriptional machinery regulating a variety of cellul
237 nk between FGF signaling and crystallin gene transcriptional machinery remains to be established.
239 on factor IIH (TFIIH) is part of the general transcriptional machinery required by RNA polymerase II
240 ilitate the subsequent access of the general transcriptional machinery required for transcriptional i
241 fic genes through interaction with NRSF/REST transcriptional machinery, resulting in the transition f
242 cribe the interaction of BRCA1 with the core transcriptional machinery (RNA polII); (iii) describe ho
243 inks sister chromatids but also inhibits the transcriptional machinery's interaction with and movemen
245 their interaction with key components of the transcriptional machinery, such as CREB-binding protein,
246 While additional components of the RNAPII transcriptional machinery, such as TFIIB and CDK7, are r
248 e are few examples of core components of the transcriptional machinery that are directly controlled b
250 FOXO1 as the molecular node of an intricate transcriptional machinery that confers the signal of duo
251 e expression, is a critical component in the transcriptional machinery that controls sensory neuron s
252 describe a simple modification of the yeast transcriptional machinery that extends the success of si
253 a direct link between ERK signaling and the transcriptional machinery that governs pluripotency.
254 sponse to corticosterone by impacting on the transcriptional machinery that is regulated by classical
255 t NO, directly or indirectly, may modify the transcriptional machinery that is responsible for the in
256 of how miR-155 causes disruption of the BCL6 transcriptional machinery that leads to up-regulation of
257 ur work sheds light on new components of the transcriptional machinery that maintain steady-state lev
258 differentiation of Th2 cells, as part of the transcriptional machinery that regulates IL-4 production
259 ations, or by directly manipulating the host transcriptional machinery that regulates the induction o
261 ovide a foundation for identification of the transcriptional machinery that specifies neurotrophin re
262 ng activity of Taf1, a component of the core transcriptional machinery that was recently reported to
263 or advances in characterizing the eukaryotic transcriptional machinery, the function of promoter-spec
264 the accessibility of promoter regions to the transcriptional machinery, the kinetics of assembly of t
265 domain (NRD) that suppresses recruitment of transcriptional machinery through autoregulation of the
266 ut not PARP-1, is a critical component in AR transcriptional machinery through interacting with the p
267 ranscription factors interact with the basal transcriptional machinery through the transcriptional co
268 cetyltransferase is a component of the viral transcriptional machinery throughout the replicative cyc
273 omes away from p63 binding sites and recruit transcriptional machinery to control tissue differentiat
274 ng factor that enhances accessibility of the transcriptional machinery to DNA within a repressive chr
275 ption factor is sufficient to co-opt somatic transcriptional machinery to drive a pro-tumorigenic gen
277 es a platform of interactions with the basal transcriptional machinery to facilitate transcription in
278 own to regulate gene expression by assisting transcriptional machinery to gain access to their sites
280 n because they recruit key components of the transcriptional machinery to modulate gene expression.
281 ral oncoprotein Tax, which utilizes cellular transcriptional machinery to perform this function.
282 in cellular regulation is the ability of the transcriptional machinery to physically access DNA.
283 ators that serve as the conduit to the basic transcriptional machinery to regulate a host of adaptive
284 ranscription factors that co-opt the general transcriptional machinery to sustain the oncogenic state
286 tivators) recruiting components of the basal transcriptional machinery to the DNA, eventually leading
287 molecule capable of recruiting the necessary transcriptional machinery to the HBV nucleocapsid promot
288 ory factor-3, CREB binding protein/p300, and transcriptional machinery to the murine ifnb1 promoter d
290 iator elements, which attract and direct the transcriptional machinery to the transcription start sit
292 atellite cell metabolism with changes in the transcriptional machinery toward myogenic commitment.
296 gnal relay from PRR complexes to the nuclear transcriptional machinery via intracellular kinase casca
297 physiological signals, eviction of the core transcriptional machinery was accompanied by the appeara
298 ils of how influenza viruses hijack the host transcriptional machinery, we aim to uncover novel targe
299 id and efficient reprogramming of the host's transcriptional machinery, which does not occur in the a
300 st that L1s have evolved to present the host transcriptional machinery with a minimally disruptive pr