ライフサイエンスコーパス: transcriptional regulation

1 with profound implications for understanding transcriptional regulation.

2 sites can provide mechanistic insights into transcriptional regulation.

3 significance in biological processes beyond transcriptional regulation.

4 t of the 3D spatial organization of genes in transcriptional regulation.

5 the SOD4 and SOD5 genes strongly differed in transcriptional regulation.

6 e stress tolerance, signal transduction, and transcriptional regulation.

7 and their tissue-specific effects influence transcriptional regulation.

8 ontrols a splicing program distinct from its transcriptional regulation.

9 up-regulate genes involved in cell-cycle and transcriptional regulation.

10 ibosome-mediated quality control with global transcriptional regulation.

11 e functional impact of context-specific post-transcriptional regulation.

12 gene modules related to mucosal biology and transcriptional regulation.

13 from cellular stress responses, signaling to transcriptional regulation.

14 set of genes that are direct targets of PIF transcriptional regulation.

15 ng 5'UTR sequences crucial for chinmo's post-transcriptional regulation.

16 ne is a model regulatory system with complex transcriptional regulation.

17 ) nuclear export, creating a microdomain for transcriptional regulation.

18 n interactions (PAIs) play a pivotal role in transcriptional regulation.

19 ed to find out the probable pathways of post-transcriptional regulation.

20 ve crucial roles in nucleosome stability and transcriptional regulation.

21 ol endocrine and metabolic responses through transcriptional regulation.

22 ation, genomic integrity and, fundamentally, transcriptional regulation.

23 ns with epigenetic methylation, and roles in transcriptional regulation.

24 alpha, ERbeta), is an important mechanism of transcriptional regulation.

25 d, as well as the magnitude and direction of transcriptional regulation.

26 r RNAs and the overall structural aspects of transcriptional regulation.

27 networks and for studying the biophysics of transcriptional regulation.

28 tal development, synaptic communication, and transcriptional regulation.

29 inding, imposing an additional level of post-transcriptional regulation.

30 in interaction plays important roles in post-transcriptional regulation.

31 ing an unmodified SP6A, could be due to post-transcriptional regulation.

32 arly contribute to cohesin stabilization and transcriptional regulation.

33 nctions such as DNA repair, replication, and transcriptional regulation.

34 ated the involvement of KLF5 in DbCM and its transcriptional regulation.

35 signaling events, chromatin organization and transcriptional regulation.

36 responses: cooperation with NF-kappaBp65 in transcriptional regulation.

37 tures associated with genome instability and transcriptional regulation.

38 24 having an essential role in ERK-dependent transcriptional regulation.

39 fic ones, is important for the study of gene transcriptional regulation.

40 read investigation into the genetic basis of transcriptional regulation.

41 early Drosophila embryo, a model system for transcriptional regulation.

42 that venous identity is the result of active transcriptional regulation.

43 part of chromatin modification required for transcriptional regulation.

44 xts are critical to decipher the dynamics of transcriptional regulation.

45 ghly translated, indicating alternative post-transcriptional regulation.

46 hereby coupling mitochondrial metabolism and transcriptional regulation.

47 n the PML nuclear bodies also plays roles in transcriptional regulation.

48 uding Lgr5, Tgfb1 and Tgfbr2, for subsequent transcriptional regulation.

49 synthesis of secondary metabolites driven by transcriptional regulation.

50 sm, but with immune function, signalling and transcriptional regulation.

51 s achieved via both transcriptional and post-transcriptional regulation.

52 would provide a mechanism for heme-dependent transcriptional regulation.

53 it appears to contribute to both H3K27ac and transcriptional regulation.

54 w DAP associations contribute to genome-wide transcriptional regulation.

55 polymerase II (Pol II) is a critical step in transcriptional regulation.

56 genesis, infection and immune responses, and transcriptional regulation.

57 target genes and represent maps of potential transcriptional regulation.

58 the sigma regulator, ultimately resulting in transcriptional regulation.

59 ical, looping, distal enhancer-based form of transcriptional regulation.

60 cope and efficiencies of genetic editing and transcriptional regulation.

61 n contributions for coactivator assembly and transcriptional regulation.

62 Cooperative DNA binding is a key feature of transcriptional regulation.

63 ole in chromatin remodeling, DNA repair, and transcriptional regulation.

64 start sites (TSSs) is key for understanding transcriptional regulation.

65 of enhancer-promoter interactions underlying transcriptional regulation.

66 variant prioritization methods only focus on transcriptional regulation.

67 new efficient tool to study type I collagen transcriptional regulation.

68 rane signaling, intracellular signaling, and transcriptional regulations.

69 egulation modules corresponding to perturbed transcriptional regulations.

70 In addition to transcriptional regulation, a sequence motif in the 3' U

71 o candidate proteins that might mediate this transcriptional regulation: a barley PHR1 ortholog and a

72 39a1, Dcd, Lbp, Scly, Slc23a1, and Tkfc) and transcriptional regulation (Ablim3).

73 de new perspectives on the interplay between transcriptional regulation and 3D genome organization.

74 ed in nerve function, signaling, metabolism, transcriptional regulation and chromatin modification.

75 ferent contexts, but their specific roles in transcriptional regulation and chromatin organization ne

76 ations indicate the critical role of NKAP in transcriptional regulation and demonstrate that perturba

77 nding proteins (RBPs) play key roles in post-transcriptional regulation and disease.

78 eosome remodeler Ino80 in chromatin-mediated transcriptional regulation and genome maintenance in cor

79 hyltransferase MLL4 is centrally involved in transcriptional regulation and is often mutated in human

80 To further explore the relationship between transcriptional regulation and metabolism, we analyzed f

81 weight, an important domestication trait, by transcriptional regulation and modulation of the transpo

82 Transport, storage, evaporative loss, transcriptional regulation and precursor competition may

83 While attention has been paid to changes in transcriptional regulation and protein signaling, much l

84 at histone modifications are instructive for transcriptional regulation and represent an epigenetic '

85 crucial importance for the understanding of transcriptional regulation and the interpretation of dis

86 epigenetic mark that plays a crucial role in transcriptional regulation and the pathogenesis of vario

87 rrest, providing a possible link between the transcriptional regulation and tumor suppression.

88 lts suggest that XPB plays a key role in HIV transcriptional regulation and XPB degradation by SP str

89 mposition of protein complexes, signal flow, transcriptional regulation, and cellular phenotype.

90 Here we have investigated the expression, transcriptional regulation, and function of the collagen

91 oncogene, which co-operates with EWS-FLI1 in transcriptional regulation, and plays a key pro-survival

92 including genome-wide histone modification, transcriptional regulation, and RNA processing, and ther

93 iosis, is crucial for piRNA biogenesis, post-transcriptional regulation, and spermiogenesis.

94 ne signaling in the striatum, CDK1-modulated transcriptional regulation, and the genetic susceptibili

95 ctional categories related to cancer such as transcriptional regulation, apoptosis, signal transducti

96 owever, the mechanisms that underlie mitotic transcriptional regulation are unclear.

97 Pattern formation is influenced by transcriptional regulation as well as by morphogenetic m

98 d widespread subunit-specific differences in transcriptional regulation, as BRG1 promoter interaction

99 Notch signaling maintains Fgf8 expression by transcriptional regulation at the promoter level.

100 aging corresponding mRNA levels through post-transcriptional regulation based on nucleotide sequence

101 seem to be under a classical redox-sensitive transcriptional regulation, being unresponsive to heme i

102 cifying known and novel pathways of CVD (eg, transcriptional regulation, brain-derived neurotrophic f

103 Both complexes are necessary for transcriptional regulation but through different mechani

104 These findings demonstrate the breadth of transcriptional regulation by FoxO1 during cardiac hyper

105 ification of novel mechanisms including post-transcriptional regulation by microRNA (miRNA) contribut

106 nes function in defense while some are under transcriptional regulation by mitogen-activated protein

107 Transcriptional regulation by nuclease-deficient CRISPR/

108 t, and gene expression, with emphasis on how transcriptional regulation by p27 illuminates its action

109 of C/G in this motif markedly reduced Col3a1 transcriptional regulation by PTH1R and Mkl-1.

110 Using the context of transcriptional regulation by steroid hormone receptors,

111 hanisms connecting chromatin remodeling with transcriptional regulation by the clock.

112 ecular terms, this signal is translated into transcriptional regulation by the N-degron pathway, ther

113 at such oscillations might be underpinned by transcriptional regulation by the recruitment of ETS fam

114 studied at the transcriptome level, how post-transcriptional regulation contributes to their chemores

115 (TF) binding is fundamental to understanding transcriptional regulation, control of cellular states,

116 ations, which showed mutations in EPAS1, and transcriptional regulation differences in EGLN1, causing

117 obands harbor both transcriptional- and post-transcriptional-regulation-disrupting de novo mutations

118 to a variety of nuclear processes including transcriptional regulation, DNA replication, and DNA dam

119 (EGFR), are important for processes such as transcriptional regulation, DNA-damage repair, and cance

120 Here, we report a disorder of transcriptional regulation due to missense mutations in

121 r results highlight not only the dynamics of transcriptional regulation during early floral developme

122 cted let-7-independent function of LIN28B in transcriptional regulation during neuroblastoma pathogen

123 e genetic mutations likely caused a holistic transcriptional regulation (e.g., biofilm formation, oxi

124 ng those associated with transcriptome, post-transcriptional regulation, epigenetics, proteomics, met

125 investigated their effects on HIF-dependent transcriptional regulation, erythropoietin production, a

126 o accurately detect differential alternative transcriptional regulation events and associate them to

127 levels, contrary to the generally described transcriptional regulation for long-term satiety via lep

128 new layer of critical nonenzymatic roles in transcriptional regulation for these proteins.

129 and alternative splicing (AS)-mediated post-transcriptional regulation has been extensively studied

130 While mechanisms of transcriptional regulation have been extensively analyse

131 s models for how this activity is coupled to transcriptional regulation have been proposed.

132 me-wide analyses of roles for minimal G4s in transcriptional regulation have been reported, Long G4-c

133 , due to either variations in copy number or transcriptional regulation, have also been linked to Alz

134 rent understanding of pDC biology, including transcriptional regulation, heterogeneity, role in antiv

135 is unclear which motifs are prone to impact transcriptional regulation if mutated.

136 The latter two suggest an important role for transcriptional regulation in AD pathogenesis.

137 Our work points to the importance of transcriptional regulation in adult glia for neurotransm

138 ld inform research on nearly every aspect of transcriptional regulation in B. subtilis.

139 ynamic models of gene regulation can predict transcriptional regulation in bacteria, but in eukaryote

140 and illuminating mechanisms of chromatin and transcriptional regulation in cancer and normal cells.

141 ents an important tool in investigating post-transcriptional regulation in cancer on a high-throughpu

142 clear organization, transcriptional and post-transcriptional regulation in defining covariations.

143 man CHDs, with implications for quantitative transcriptional regulation in disease.

144 s are now widely used for genome editing and transcriptional regulation in diverse organisms.

145 ing that PAI-1 may mediate actions of ASC on transcriptional regulation in EEC.

146 s and is considered a point of reference for transcriptional regulation in Escherichia coli K12.

147 To study post-transcriptional regulation in G0 leukemic cells, we syst

148 family provides important new insights into transcriptional regulation in human cells by members of

149 Our results point to a role of AGO1 in transcriptional regulation in human cells that is indepe

150 lt to decipher the biophysical mechanisms of transcriptional regulation in living cells and determine

151 ce, not much is known about the role of post-transcriptional regulation in mediating responses to abi

152 obe links between 3D genome organization and transcriptional regulation in mouse stem cells.

153 at this translation factor may contribute to transcriptional regulation in neurons, and suggest a the

154 nd underscore the importance of MEIS1-HOXB13 transcriptional regulation in suppressing prostate cance

155 gate the role of histone acetylation in G1/S transcriptional regulation in the budding yeast Saccharo

156 Our observations imply conserved MYB transcriptional regulation in the control of the cutin b

157 Here, we have studied cti transcriptional regulation in the solvent-tolerant strai

158 was performed to understand the role of post-transcriptional regulation in various silicon-related ce

159 We propose that transcriptional regulation incorporates a feedback mecha

160 coactivator recruitment and antagonizing the transcriptional regulation induced by 1alpha,25-dihydrox

161 ss precursors; 2) metabolic genes subject to transcriptional regulation involved in Staphyloxanthin b

162 The post-transcriptional regulation involved in the responses of

163 herefore, we describe a mechanism of dynamic transcriptional regulation involving p300-mediated acety

164 However, when post-transcriptional regulation is acquired and how protein s

165 kingly, the FadR theme of acyl-CoA-dependent transcriptional regulation is found in a different trans

166 Specificity in transcriptional regulation is imparted by transcriptiona

167 subject to modulation, information about its transcriptional regulation is limited.

168 Whereas the majority of transcriptional regulation is mediated by DNA-binding tr

169 sing pan-method approaches, we discover that transcriptional regulation is predominant in D1-MSNs, wh

170 This emerging role of PTEN on global transcriptional regulation is providing a better underst

171 een intensively studied in carrot roots, and transcriptional regulation is thought to be the major fa

172 Understanding HBV transcriptional regulation may be critical to develop a

173 The transcriptional regulation mechanism of the Cyp3a gene i

174 role for PRDM8 downregulation as a potential transcriptional regulation mechanism, analogous to that

175 ved in treatment with antipsychotics and the transcriptional regulation mechanisms exerted by NURR1.

176 nes are subject to sophisticated programs of transcriptional regulation, mediated by DNA sequences th

177 suggest that mechanistic models of combined transcriptional regulation must be able to reproduce a r

178 Using neuronal tissues, we reveal a broad transcriptional regulation network associated with wild-

179 s and allow reliable constructions of global transcriptional regulation networks encoded in a specifi

180 uction of dbpBA indicates a RpoS independent transcriptional regulation occurring in the mammalian cy

181 sted that PXY and ER cross- and inter-family transcriptional regulation occurs, but it differs betwee

182 calization of androgen receptor (AR) directs transcriptional regulation of a host of genes, referred

183 However, transcriptional regulation of ABI5 is not fully understo

184 NAs and targets, but also a view of the post-transcriptional regulation of adaptations.

185 e the importance of transcriptional and post-transcriptional regulation of antioxidant response in AD

186 Transcriptional regulation of AZ development appears to

187 s to further characterize the spatiotemporal transcriptional regulation of B. burgdorferi during mamm

188 y regulating chromatin accessibility and the transcriptional regulation of canonical macrophage genes

189 However, little is known about the transcriptional regulation of carotenoid biosynthetic ge

190 rstand the role of this putative enhancer in transcriptional regulation of Cebpe, we targeted it usin

191 unique quantitative framework to understand transcriptional regulation of cell differentiation in a

192 Yet, how transcriptional regulation of cell-cycle and self-renewa

193 This effect involves, at least in part, transcriptional regulation of chlorophyll biosynthesis a

194 nderstanding of the transcriptional and post-transcriptional regulation of chondrogenesis will enable

195 1/BMP signaling determines body size through transcriptional regulation of cuticle collagen genes.

196 , our study provides novel insights into the transcriptional regulation of CYP3A in the liver.

197 ivation of DUX requires GRSF1-dependent post-transcriptional regulation of Dux mRNA.

198 However, the molecular mechanisms underlying transcriptional regulation of EC and tumor angiogenesis

199 Though the transcriptional regulation of EPO has been well studied,

200 opsis (Arabidopsis thaliana) converge on the transcriptional regulation of FLOWERING LOCUS T (FT), en

201 ropose several mechanisms to account for the transcriptional regulation of GATA-targeted genes.

202 ay important roles in translational and post-transcriptional regulation of gene expression and biolog

203 RNAs that function in RNA silencing and post-transcriptional regulation of gene expression in most or

204 The latter properties are subject to post-transcriptional regulation of gene expression, meriting

205 molecular machines that act as hubs for post-transcriptional regulation of gene expression.

206 Our findings highlight the pivotal role of transcriptional regulation of genes involved in the glut

207 g a KIP-related protein, was found to be the transcriptional regulation of genes responsible for cell

208 s functionality, we explore the function and transcriptional regulation of grapevine EXPANSIN genes.

209 The effects of such perturbations on the transcriptional regulation of Hoxd genes illustrate the

210 In this Review, we discuss the transcriptional regulation of human TERT, hTR processing

211 on of inhibitory Smad 6/7-dependent negative transcriptional regulation of ID1, rendering the latter'

212 revolutionized our understanding of the post-transcriptional regulation of inflammatory genes by reve

213 led functional iron deficiency, altered post-transcriptional regulation of iron metabolism genes, and

214 xerts tumor-promoting effects in AML by post-transcriptional regulation of its critical targets such

215 lished a causal link between temperature and transcriptional regulation of Kdm6b We show that signal

216 d LATE4 and show that they contribute to the transcriptional regulation of key flowering genes, inclu

217 ylpropanoid metabolic crosstalk involves the transcriptional regulation of KFB genes that initiate th

218 ovided mechanistic insights into divergently transcriptional regulation of KPNA2, thus pointing to KP

219 roductive system defects suggest that proper transcriptional regulation of lag-1 confers robustness t

220 Transcriptional regulation of lineage specificity is lin

221 siological functions, epigenetic regulation, transcriptional regulation of lncRNAs, and their importa

222 eport results from two experiments measuring transcriptional regulation of MAA and aromatic amino aci

223 in lipid metabolism, LXRs participate in the transcriptional regulation of macrophage activation and

224 Transcriptional regulation of marker genes of medium spi

225 These results suggest that the transcriptional regulation of mer in T. thermophilus is

226 plexes with SPI1 and BATF as central for the transcriptional regulation of miR-155.

227 eam of miR-17-92 are largely elusive and the transcriptional regulation of miR-17-92 is not fully und

228 Transcriptional regulation of mRNA expression is necessa

229 urrounding cues require temporally concerted transcriptional regulation of multiple genes.

230 Phloem-specific TmMYB3 plays a role in the transcriptional regulation of paclitaxel biosynthesis, a

231 d-type but not E7 mutant virus had perturbed transcriptional regulation of pathways previously identi

232 likely to be distinct from its known role in transcriptional regulation of phenylpropanoid biosynthet

233 pmental classes, precise genomic origins and transcriptional regulation of postnatal piRNAs remain un

234 Dynamic post-transcriptional regulation of protein-coding and non-cod

235 y regulate the Hh-signaling activity through transcriptional regulation of Ptch1, a known Hh-signalin

236 These findings provide insights into the transcriptional regulation of raffinose biosynthetic gen

237 ing, CEFCIG reveals unique histone codes for transcriptional regulation of reported CIGs, and utilize

238 cultivar-specific mechanisms of cold-induced transcriptional regulation of ripening in European pear,

239 Post-transcriptional regulation of RNA stability is a key ste

240 Post-transcriptional regulation of RNAs is critical to the di

241 y of the SHR-SCR complex as well as upstream transcriptional regulation of SHR and SCR.

242 suggest that ShMYB78 may be involved in the transcriptional regulation of suberin deposition, from f

243 These findings indicate that post-transcriptional regulation of tankyrase serves as a liga

244 tivity required for NRF1- and NRF2-dependent transcriptional regulation of TFAM, TFB1M, and TFB2M, re

245 ontrols water tightness of tracheal tubes by transcriptional regulation of the delta-aminolevulinate

246 receptor PPARalpha, which participate in the transcriptional regulation of the Fgf21 gene.

247 related with FA-VOC content, consistent with transcriptional regulation of the first step in the path

248 Transcriptional regulation of the Foxp3 gene has been st

249 wild-type and IQGAP1-null mice revealed that transcriptional regulation of the gluconeogenesis genes

250 Transcriptional regulation of the proteasome can dictate

251 The underlying mechanism involves transcriptional regulation of the putative tRNA and rRNA

252 Here, we investigated transcriptional regulation of the respiratory l-lactate

253 ional targets of miRNAs and the mechanism of transcriptional regulation of the same targets can shed

254 ovides crucial mechanistic insights into the transcriptional regulation of these genes.

255 Less is known about direct transcriptional regulation of these responses, however.

256 cent findings on the molecular structure and transcriptional regulation of this gene.

257 Although substantial post-transcriptional regulation of this hardwired program has

258 Igf2 and affects directly or indirectly the transcriptional regulation of thousands of genes.

259 was used to delve the mechanisms underlying transcriptional regulation of TNF-alpha-stimulated VCAM-

260 nctions of piRNAs in the epigenetic and post-transcriptional regulation of transposons and genes.

261 through wound-induced JA production via the transcriptional regulation of upstream clade-III MAP3Ks,

262 tivator protein IE2 work in tandem to enable transcriptional regulation of viral gene.

263 Our data strongly imply that transcriptional regulation of wg by Pol II pausing facto

264 We studied transcriptional regulation of ZEB1, ITGA3, ITGB1, JNK, a

265 enzyme and not H3K4 trimethylation underlies transcriptional regulation on MLL2/COMPASS targets.

266 DGCs are essential for the Hfq-mediated post-transcriptional regulation on RsmB.

267 eer factors have revealed their functions in transcriptional regulation, pioneer factors that open ch

268 Post-transcriptional regulation plays important roles to fine

269 Our results suggest that transcriptional regulation primarily acts by changing th

270 rocesses, including proteasomal degradation, transcriptional regulation, regulation of protein-protei

271 involved in maintaining chromatin structure, transcriptional regulation, RNA pre-spliceosome assembly

272 tial nuclear L1 binding partners involved in transcriptional regulation, RNA processing and transport

273 Here, we show that in mouse liver, transcriptional regulation significantly contributes to

274 11), forming a signal-integration hub for co-transcriptional regulation that includes translation-bas

275 ne learning to build interpretable models of transcriptional regulation that predict ~94% of the expr

276 nstrate an imperative role of PTEN in global transcriptional regulation that will provide a new direc

277 Repo levels modulate, via transcriptional regulation, the ability of glial cells t

278 , consistent with the role of Hoxa13 in Hoxd transcriptional regulation, the expression of Hoxd13 in

279 RNA-SMG1.72 (circRNA-SMG1.72) expression via transcriptional regulation through directly binding to t

280 ory atlas provides a trove of information on transcriptional regulation through immune differentiatio

281 Its pathogenesis comprises subversion of transcriptional regulation, through mutation and by hija

282 nd are implicated in multiple functions from transcriptional regulation to cell junction remodelling.

283 Tailoring transcriptional regulation to coordinate the expression

284 e same cells would permit direct matching of transcriptional regulation to its outputs.

285 y serve as a general microbial mechanism for transcriptional regulation to synchronize genetic respon

286 ene expression analysis revealed Geobacter's transcriptional regulations to express more electron-rel

287 sis, ARSs are also involved in RNA splicing, transcriptional regulation, translation, and other aspec

288 we sought to understand the role of PTEN in transcriptional regulation under metabolic stress, a con

289 nsights into the role of histone residues in transcriptional regulation under stress conditions.

290 These studies uncover post-transcriptional regulation underlying chemoresistance in

291 iological processes by furthering studies of transcriptional regulation, untranslated regions, genome

292 x differences in subcutaneous adipose tissue transcriptional regulation using omic-scale data from ~3

293 ase and tensin homolog (PTEN) in genome-wide transcriptional regulation using PTEN overexpression and

294 volved in transcription, RNA processing, and transcriptional regulation was more likely to be conserv

295 To understand CTCF's direct role in global transcriptional regulation, we integrated the miniAID-mC

296 To understand MLL2-dependent transcriptional regulation, we performed a CRISPR-based

297 Key players in both metabolism and transcriptional regulation were identified as required f

298 e lncTASR (ENST00000600671.1) expression via transcriptional regulation, which might then increase AX

299 transcription-reconciles high specificity of transcriptional regulation with fast regulatory kinetics

300 al modules involved in synaptic function and transcriptional regulation, with ASD risk variants addit