ライフサイエンスコーパス: transduction pathway

1 ese genes to investigate the c-di-GMP signal transduction pathway.

2 ing those involved in the phytochrome signal transduction pathway.

3 ough a hitherto unknown communication signal transduction pathway.

4 al transporter that acts as a processor in a transduction pathway.

5 unoreceptor tyrosine-based activation signal transduction pathway.

6 the cJun NH(2)-terminal kinase (JNK) signal transduction pathway.

7 nflammation or activation of the STAT signal transduction pathway.

8 he Toll-like receptor 4 (TLR4) immune signal transduction pathway.

9 es harboring components of the visual signal transduction pathway.

10 ggesting early activation of the STAT signal transduction pathway.

11 otential "communication hub" for this energy transduction pathway.

12 in cell proliferation through the Shh signal transduction pathway.

13 nase/mitogen-activated protein kinase signal transduction pathway.

14 ellular signal-regulated kinase (ERK) signal transduction pathway.

15 by constitutive activation of the Ras signal transduction pathway.

16 n regulating protein stability and signaling transduction pathways.

17 key regulator of protein function in signal transduction pathways.

18 act indirectly via receptor-mediated signal transduction pathways.

19 d carcinoma and describe the involved signal transduction pathways.

20 s as a mediator of cross-talk between signal transduction pathways.

21 ternal stimuli to regulate downstream signal transduction pathways.

22 teins into complexes, organelles, and signal transduction pathways.

23 ell transformation and the associated signal transduction pathways.

24 were used to determine activation of signal transduction pathways.

25 nsory physiology and modulate various signal transduction pathways.

26 rt mechanical integrity and influence signal transduction pathways.

27 ommunicate with their environment via signal transduction pathways.

28 biogenesis, and phosphorylation-based signal transduction pathways.

29 essenger that plays a central role in signal transduction pathways.

30 genes, and dysregulation of multiple signal-transduction pathways.

31 volutionarily conserved regulators of signal transduction pathways.

32 asured responses of a few proteins or signal transduction pathways.

33 or conformations activating different signal transduction pathways.

34 adation, subcellular localization and signal transduction pathways.

35 vous system functions through diverse signal transduction pathways.

36 ule frequency in reaction to internal signal transduction pathways.

37 Gsk-3) is a key regulator of multiple signal transduction pathways.

38 o cancer treatment focus on targeting signal transduction pathways.

39 cellular regulation of immune system signal transduction pathways.

40 the critical steps for many cellular signal transduction pathways.

41 r outputs and responses by modulating signal transduction pathways.

42 xert reversible control over numerous signal transduction pathways.

43 aling factors involved in many intracellular transduction pathways.

44 esis 8 (DOCK8), which are involved in signal transduction pathways.

45 s, and is often activated by multiple signal transduction pathways.

46 nuated signaling through the STAT3 and c-Src transduction pathways.

47 ized by their involvement in critical signal transduction pathways.

48 re not simply downstream executors of signal transduction pathways.

49 interactions that stimulate numerous signal transduction pathways.

50 on that is necessary in understanding signal transduction pathways.

51 how SUMOylation regulates a number of signal transduction pathways.

52 and function as scaffolds for various signal transduction pathways.

53 ownstream signaling effectors in many signal transduction pathways.

54 and pathways, including signaling and signal transduction pathways.

55 was involved in known sweet and bitter taste transduction pathways.

56 l activation reveal key insights into signal transduction pathways.

57 versible, PTMs serve as regulators of signal transduction pathways.

58 ough the modulation of key components of the transduction pathways.

59 owever, display decreased activation of pain transduction pathways.

60 iptional regulation and activation of signal transduction pathways.

61 roteins involved in a wide variety of signal transduction pathways.

62 cificity for directing protein kinase signal transduction pathways.

63 trafficking, and the organization of signal transduction pathways.

64 Epr3 is integrated into the symbiosis signal transduction pathways.

65 a cells and for the study of involved signal transduction pathways.

66 embrane trafficking and to control signaling transductions pathways.

67 unction as an integrated two-receptor signal transduction pathway, a finding with implications for ra

68 Developmental signal transduction pathways act diversely, with context-depend

69 Many signal transduction pathways activate RhoA-for instance, Galpha

70 Signal transduction pathways activated by chemoattractants have

71 also one of the major players in the signal transduction pathways activated in response to DNA damag

72 sponses depending upon the balance of signal transduction pathways activated, targeting specific VEGF

73 e, we observed that perturbation in estrogen transduction pathway altered MHC Class II, alpha-AChR, a

74 which binds to a crucial site in the agonist transduction pathway and causes conformational changes t

75 ctivation of TAK-1 by the TLR-4/MyD88 signal transduction pathway and MLCK by NF-kappaB p65/p50 regul

76 ports a PIEZO1-independent mechanoelectrical transduction pathway and modulates cellular adhesions an

77 ance signaling molecules that control signal transduction pathways and are necessary for cellular hom

78 Integrating changes in signal transduction pathways and cellular metabolism is essenti

79 onal modification controlling several signal transduction pathways and displaying an acute effect on

80 We address both biochemical signal-transduction pathways and engineering principles of desi

81 L2 is a crucial modulator of multiple signal transduction pathways and functions as a scaffold in spe

82 chicken genes and pathways, including signal transduction pathways and immune system processes, in ad

83 are known to participate in canonical signal transduction pathways and in the regulation of actin cyt

84 tin cytoskeletal dynamics, regulating signal transduction pathways and inhibiting host secretory path

85 ing the action of ethylene through different transduction pathways and its interaction with other hor

86 concentrations, which disrupt normal signal transduction pathways and lead to an overactivation of m

87 G-protein-coupled receptors regulate signal transduction pathways and play diverse and pivotal roles

88 Uncovering the missing elements of signal transduction pathways and psbA gene expression could ope

89 kinase 1/2, and ribosomal S6 kinase 1 signal transduction pathways and subsequent increase in cAMP re

90 ole of the ERM proteins in regulating signal transduction pathways and suggests that modulation of mo

91 cover the links between the classical signal transduction pathways and the physical mechanisms that a

92 od with our evolved knowledge of many signal transduction pathways and the way they converge and regu

93 itecture to integrate the activity of signal transduction pathways and transcriptional regulators, an

94 sed different, functionally unrelated signal transduction pathways and were expressed in different re

95 t responses, it should act through different transduction pathways and/or in conjunction with other s

96 hoinositide 3-kinase/protein kinase B signal transduction pathway, and that can be overcome by miR-7

97 ll cycle control, microRNA silencing, signal transduction pathways, and hormone-driven disease.

98 are tightly controlled by enzymes and signal transduction pathways, and their dysregulation leads to

99 cross-talk among the external milieu, signal transduction pathways, and transcription factors that di

100 -IL-1beta, generally via NF-kappaB-dependent transduction pathways; and the assembly and activation o

101 e also signalling molecules whose respective transduction pathways are being intensively studied.

102 ms biology approaches to defining how signal transduction pathways are integrated at the level of who

103 Host cell signal transduction pathways are often targets of bacterial pat

104 ain downstream effectors of the Hippo signal transduction pathway, are emerging as pivotal determinan

105 to induce cardioprotection, and their signal transduction pathways, are discussed.

106 tes in the canonical Wnt/beta-catenin signal transduction pathway as well as modulating cytoskeleton

107 Increasing knowledge about signal transduction pathways as drivers of cancer growth has el

108 udy are the first to define the LytSR signal transduction pathway, as well as determine the metabolic

109 luenced by all targets were primarily signal transduction pathways associated with CF, including PI3K

110 ligand-specific activation of certain signal transduction pathways at a receptor that can signal thro

111 By contrast, a transduction pathway based on [Formula: see text] efflux

112 nner and therefore fills a gap in the signal transduction pathway between pathogen recognition and SA

113 ia FGF receptor 4 (Fgfr4), mediates a signal-transduction pathway between Wnt16 and Dlc, but not Dld,

114 s are controlled by a small number of signal-transduction pathways, but how the specificity of functi

115 hylation is an important modulator of signal transduction pathways, but methyltransferases themselves

116 Our data suggest a complete signal transduction pathway by which cAMP increases NCC phospho

117 pressed only in males, as well as the signal transduction pathway by which episodic GH solely regulat

118 ese data uncover a previously unknown signal transduction pathway by which the SE facilitates protein

119 ors, and some family members modulate signal transduction pathways by acting as co-receptors.

120 A common approach is to insulate signal-transduction pathways by minimizing molecular-level cros

121 However, the signal transduction pathways by which extracellular signals reg

122 Changes in these signal transduction pathways can lead to differential gene regu

123 stresses are often very specific, but signal transduction pathways can partially or completely overla

124 d membrane-trafficking intermediates, signal transduction pathways, cell cycle regulators, the organe

125 with disruptions of cAMP and/or AprA signal transduction pathway components, and delineated the AprA

126 id (ABA) that acts through a receptor-signal transduction pathway comprising a PYRABACTIN RESISTANCE

127 h is controlled through a proteolytic signal transduction pathway comprising a sensor protein (MecR1)

128 Serotonin acts through a signal transduction pathway conserved between C. elegans and ma

129 haracterise a multi-step phosphorelay signal transduction pathway consisting of TcsA, TcrA, FsrR, Rpo

130 oth species, including multiple r-opsins and transduction pathway constituents, congruent with immuno

131 the phosphoinositide 3-kinase (PI3K) signal transduction pathway contribute to the hypothalamic regu

132 GTPase signal transduction pathways control cellular decision making b

133 In normal cells, signal transduction pathways control core cellular functions, i

134 Multiple wound-related signal transduction pathways control the deposition of EDA FN,

135 ase 3 (SIK3) as the central node in a signal transduction pathway controlling glial K(+) and water ho

136 ellular stress response; however, the signal transduction pathways controlling autophagy induction in

137 Ras is at the hub of signal transduction pathways controlling cell proliferation and

138 icating that targeting a specific D2R signal transduction pathway could allow for more precise modula

139 profiles of genes enriched in several signal transduction pathways critical for coronary heart diseas

140 o and regulates synaptic adhesion and signal transduction pathways critical for normal cognition and

141 However, the signal transduction pathways culminating in the biological cons

142 ation of several processes, including signal transduction pathways, development, and disease.

143 skeletal protein networks and complex signal transduction pathways driven by localized proteins.

144 g pathway is considered to be a major signal transduction pathway during embryonic development, but i

145 in vivo the requirement of different signal transduction pathways emanating from KIT for tumorigenes

146 ellular factors and the intracellular signal transduction pathways engaged in this process remain lar

147 Activation of the EphR-Ephrin signal transduction pathway enhances S863 phosphorylation.

148 ction as modulators of a multitude of signal transduction pathways evoked by environmental stimuli.

149 en proposed to play a central role in signal transduction pathways evoked by the drought and stress h

150 PhoB and TctD mediated two-component signal transduction pathways exemplify how P. aeruginosa may ex

151 s or complement, suggesting that alternative transduction pathways exist.

152 rough direct interactions with ILK, a signal transduction pathway firmly linked to cell motility and

153 s as a key control element in the allosteric transduction pathway for potentiating betaEST and dFBr.

154 The signal transduction pathways for the cross talk between the rem

155 NPM-ALK co-opts several intracellular signal transduction pathways, foremost being the STAT3 pathway,

156 Notch signaling is a ubiquitous signal transduction pathway found in most if not all metazoan c

157 with sphingolipid metabolism and link signal transduction pathways from the plasma membrane to the re

158 This result allowed us to elucidate transduction pathways from twin drug-binding cavities to

159 The evolutionary conserved Wnt signal transduction pathway has long been known for its importa

160 Disruption of such metabolic transduction pathways has severe consequences for the en

161 Light signal transduction pathways have been extensively studied in p

162 d crucial pathways, including several signal transduction pathways, hormone response, oxidative respo

163 signaling regulation, a two-component signal transduction pathway in bacterial homeostasis, and a sig

164 This study identifies an H3K27me3-directed transduction pathway in mammals that relies on a conserv

165 environment, activating the NF-kappaB signal transduction pathway in MDSCs and regulating their quant

166 Our data describe a novel signal transduction pathway in neurons whereby ApoE activates a

167 BMP receptors and members of the SMAD signal transduction pathway in nociceptive sensitization was al

168 dopsis thaliana forward nuclear auxin signal transduction pathway in Saccharomyces cerevisiae to test

169 acterial phosphotransferase system, a signal transduction pathway in which phosphoryl transfer throug

170 re involved in multiple signaling and signal transduction pathways in a wide variety of cellular and

171 tein kinases regulate the majority of signal transduction pathways in cells and have become important

172 separate, but overlapping, mechanoelectrical transduction pathways in chondrocytes.

173 The crosstalk between these signal transduction pathways in coordinating environmental cues

174 Epigenetic enzymes modulate signal transduction pathways in different biological contexts.

175 on of IFN-kappa and its modulation by signal transduction pathways in human keratinocytes.

176 sive, validated, and annotated map of signal transduction pathways in inflammatory Mvarphis based on

177 onal signal transducer that regulates signal transduction pathways in leukocytes, including macrophag

178 Calcium is a second messenger in signal transduction pathways in plants, and it has been indirec

179 CrkL are capable of initiating major signal transduction pathways in response to extracellular stimu

180 sease, the molecular underpinnings of signal transduction pathways in the cell, and drug discovery in

181 screening-type analysis of potential signal transduction pathways in the cells.

182 lk may happen among receptor-mediated signal transduction pathways in the same host during simultaneo

183 AprA uses a subset of chemoattraction signal transduction pathways including Ras, protein kinase A, t

184 , MIF distinctly modulates every step of the transduction pathway, indicating distinct activation mec

185 al cells may over time engage various signal transduction pathways, inflammasome activation, which re

186 the extent to which modulation of the signal transduction pathways influence TNFalpha production.

187 Emerging work points to Nrf2-Keap1 signal transduction pathway inhibitors, including Bach1 and c-M

188 G proteins play a pivotal role in the signal-transduction pathways initiated by G-protein-coupled rec

189 confirms the pan-cancer importance of signal transduction pathways, innate and adaptive immune signal

190 r, broad inhibition of such a central signal transduction pathway involved in essential cellular func

191 However, the downstream signal transduction pathways involved are poorly characterised.

192 However, little is known about the signal transduction pathways involved in mechanical stimuli res

193 cisely highlight the main biochemical signal-transduction pathways involved in the biocompatibility c

194 However, signal transduction pathways involved remain largely unidentifi

195 Traditional study of signal transduction pathways involves mapping cellular signalin

196 These data define a novel signal transduction pathway involving c-src that is activated b

197 s is reported that operates through a signal transduction pathway involving multivalent interactions.

198 ar remodeling is mediated by specific signal transduction pathways involving NFAT or C/EBPbeta transc

199 e opening and that shared Ca(2+) and voltage transduction pathways involving the alphaB helix may be

200 tion is not mediated by the canonical signal transduction pathway, involving ApoER2/VLDLR and Dab1, t

201 eover, we reveal that the chemotactic signal transduction pathway is conserved in Shewanella, and his

202 vidence demonstrates that the PI3K signaling transduction pathway is linked to the pathology of IPF.

203 BR signal transduction pathway is well elucidated in Arabidopsis b

204 Fluctuation in signal transduction pathways is frequently observed during mamm

205 Temporally resolving GPCR transduction pathways is key to understanding how cell s

206 ally signal through a small number of signal transduction pathways is not well resolved.

207 lysis reveals that the 'plant hormone signal transduction' pathway is enhanced during pollen-pistil i

208 homologous yet distinct components of signal transduction pathways known to regulate cell survival an

209 Additionally, rewired kinase signal transduction pathways likely contribute to the superior

210 Signal transduction pathways mediated by p38 mitogen-activated

211 Understanding the mechanism of the signal transduction pathways mediated by these proteins may off

212 t, we examined whether Pfs47 affected signal transduction pathways mediating mosquito immune response

213 endowed with a PLCbeta2/IP3 R3/TRPC6 signal transduction pathway modulating release of neuropeptide

214 The pooled prevalence indices of signal transduction pathway mutations in gastric cancer, liver

215 between HIV-1 proteins and key human signal transduction pathways necessary for activation of CD4+ T

216 The signal transduction pathway of the DNA damage response (DDR) is

217 ver, the underlying intracellular signalling transduction pathways of alpha-syn-mediated mDA neurodeg

218 s, and compounds able to modulate the signal transduction pathways of the cannabinoid type-2 receptor

219 Treg cell outcomes through 2 distinct signal transduction pathways: one Smad3 dependent and the other

220 c events converging on the same gene, signal transduction pathway, or protein complex in different su

221 sed following stimulation by multiple signal transduction pathways, our findings also suggest that ce

222 a2+/CaM as a limiting resource in the signal transduction pathway owing to its low abundance relative

223 The signal transduction pathways present during the early phases of

224 phosphodiesterase 1C, fundamental olfactory transduction pathway proteins.

225 echanisms on the dynamics of parallel signal transduction pathways; reciprocal side-effects between s

226 ure, constitutive activity, isoforms, signal transduction pathways, regional differences in expressio

227 Signal-transduction pathways regulated by extracellular signals

228 standing of the protein complexes and signal transduction pathways regulated by RGS proteins in addic

229 iculum stress and modulating multiple signal transduction pathways regulating cancer cell growth, inv

230 anisms that negatively regulate these signal transduction pathways remain poorly understood.

231 1-Orai1 clusters but whether distinct signal transduction pathways require different cluster numbers

232 post-translational modification initiates a transduction pathway required to ensure precisely locali

233 In this study, we investigated the signal transduction pathways responsible for APOBEC3B upregulat

234 This highlights the existence of signal transduction pathway(s) that limit plant development und

235 ub-zero acclimation, although the CBF signal transduction pathway seems to be less important during s

236 Transcripts involved in signal transduction pathways, stress and antioxidant responses

237 ion 3 (STAT3), while preserving other signal transduction pathways such as Akt and extracellular sign

238 ith cytotoxic drugs and inhibitors of signal transduction pathways such as mTOR-Is.

239 rnalization and activation of several signal transduction pathways, such as phosphoinositide 3-kinase

240 Eukaryotic chemoattraction signal transduction pathways, such as those used by Dictyosteli

241 We also found signal transduction pathways tend to show extensive dynamic rel

242 tropes, we investigated the potential signal transduction pathway that conveys the inhibitory action

243 ental Cell, Ho and Treisman uncover a signal transduction pathway that coordinates muscle growth and

244 cts both like a component of the FGF4 signal transduction pathway that governs trophoblast proliferat

245 ignaling unit within a multicomponent signal transduction pathway that includes a diverse set of auxi

246 jor pathway is the canonical ethylene signal transduction pathway that incorporates CONSTITUTIVE TRIP

247 ger assembly of T6SS organelles via a signal transduction pathway that involves protein phosphorylati

248 naling is an evolutionarily conserved signal transduction pathway that is essential for metazoan deve

249 of the alpha7 nAChR is mediated by a signal transduction pathway that is independent of ion current.

250 part of an operon encoding the VieSAB signal transduction pathway that is nearly silent in V. cholera

251 tic synaptic plasticity; however, the signal transduction pathway that links reduced Ca(2+)-levels to

252 H2O2 signaling is under control of a signal transduction pathway that links the respiratory chain to

253 operate downstream of cytokinins in a signal transduction pathway that negatively regulates plant pri

254 ested this hypothesis by perturbing a signal transduction pathway that plays a major role in controll

255 in forms a central part of a mechanochemical transduction pathway that regulates multilayer communica

256 itric oxide/S-nitrosylation-dependent signal transduction pathway that regulates the growth cone cyto

257 he unfolded protein response (UPR), a signal transduction pathway that senses the fidelity of protein

258 SS activity was dependent on the same signal transduction pathway that was previously shown to be req

259 odification (PTM) is a key feature of signal-transduction pathways that allows the modulation of prot

260 gent that invokes the blockage of two signal transduction pathways that are central to the developmen

261 apable of activating several cellular signal transduction pathways that are ICP27 dependent.

262 ling, which may begin to identify the signal transduction pathways that are important in the physiolo

263 activated the PI3K.Akt and Wnt.beta-catenin transduction pathways that are known to be involved in t

264 toxin-induced death by stimulation of signal transduction pathways that are linked to prion protein.

265 re poorly understood, but may include signal transduction pathways that are modulated by changes in i

266 ncer is to understand the cellular signaling transduction pathways that cause cancer at the level of

267 Identifying the important signal transduction pathways that control monocyte chemotaxis c

268 mented IHVR, is regulated by multiple signal transduction pathways that could be potential therapeuti

269 cellular stress to the intracellular signal transduction pathways that drive the liver fasting respo

270 te to TAV by initiating outside-in signaling transduction pathways that elicit monocyte recruitment t

271 ery from pneumonia, and modulation of signal transduction pathways that have been linked to prion pro

272 activated through complex and cross-talking transduction pathways that include a mitogen-activated p

273 VEGF-A stimulates signal transduction pathways that modulate endothelial outputs

274 essed in many cancers and involved in signal transduction pathways that promote cancer cell prolifera

275 er decades of basic research into the signal transduction pathways that promote cancer cell survival,

276 Restraint of intracellular signal transduction pathways that promote release of mast cell-

277 atively little is known regarding key signal transduction pathways that serve as cytosolic bridges be

278 n extension of the established immune signal transduction pathways, thereby adding an extra layer of

279 nucleation is controlled by a glucose signal-transduction pathway through cAMP and its effector EPAC2

280 ily of photoreceptors and discuss the signal transduction pathways through which these photoreceptors

281 CWI mitogen-activated protein kinase signal transduction pathway to target the relocalization and co

282 o) GTPases regulate cell polarity and signal transduction pathways to control morphogenetic responses

283 eptors (GPCRs) utilize (at least) two signal transduction pathways to elicit cellular responses inclu

284 scovery and characterization of novel signal transduction pathways to exploring the molecular underpi

285 , ranging from epigenetic control and signal transduction pathways to global and specific transcripti

286 4, thereby integrating phase-specific signal transduction pathways to regulate cell cycle progression

287 y of proteins to fulfill key roles in signal transduction pathways triggered by activation of recepto

288 by toll-like receptor 4 (TLR-4)/MyD88 signal-transduction pathway up-regulation of MLCK expression.

289 meability was mediated by TLR-4/MyD88 signal-transduction pathway up-regulation of MLCK.

290 e protein-1 (LMP1) activates numerous signal transduction pathways using its C-terminal activating re

291 The olfactory transduction pathway was the most enriched pathways for

292 Protein kinases are key players in signal transduction pathways where they are crafted into two fu

293 Targeting signal transduction pathways which promote therapy resistance a

294 ed the Nuclear Factor-kappa B (NF-kB) signal transduction pathway, which is induced by several types

295 en lead to dysregulation of oncogenic signal transduction pathways, which in turn alters downstream t

296 likely to function in development and signal transduction pathways, while those that are mutation-tol

297 ght stress depend on highly regulated signal transduction pathways with multiple interactions.

298 for treating the disease by modifying signal transduction pathways with small-molecule drugs.

299 n the exterior of a cell and activate signal transduction pathways within the cell.

300 ons abrogated established FGF-induced signal transduction pathways, yet FGF functions such as cell-ma