ライフサイエンスコーパス: transepithelial migration

1 l and epithelial components to CD47-mediated transepithelial migration.

2 luence of hypoxia/reoxygenation (H/R) on PMN transepithelial migration.

3 hesion stability and facilitates immune cell transepithelial migration.

4 ithelial intercellular adhesions and promote transepithelial migration.

5 f each chemoattractant in driving neutrophil transepithelial migration.

6 dependent HXA3 production and subsequent PMN transepithelial migration.

7 of impeding P. aeruginosa-induced neutrophil transepithelial migration.

8 erfere with P. aeruginosa-induced neutrophil transepithelial migration.

9 c inhibition of IDO also increased human PMN transepithelial migration.

10 red the role of hepoxilin A(3) in neutrophil transepithelial migration.

11 e 2 diabetes and susceptibility to bacterial transepithelial migration.

12 se of soluble CD44v6 by T84 cells during PMN transepithelial migration.

13 orients them toward the midgut for directed transepithelial migration.

14 n TER induced by PMN contact and blocked PMN transepithelial migration.

15 1 and -2 knockdown decreased the rate of PMN transepithelial migration.

16 thelial permeability thereby facilitates PMN transepithelial migration.

17 s of resolvin E1 (RvE1) actions on leukocyte transepithelial migration.

18 monella-induced polymorphonuclear leukocytes transepithelial migration.

19 ormylmethionylleucylphenylalanine-driven PMN transepithelial migration.

20 ther necessary nor sufficient to mediate PMN transepithelial migration.

21 atory epithelial cells and chemokine-induced transepithelial migration.

22 e were unable to invade following neutrophil transepithelial migration.

23 mately, OspF and OspC1 are essential for PMN transepithelial migration, a phenotype associated with i

24 In this study, we modeled PMN transepithelial migration across T84 monolayers and demo

25 lar junctions (desmosomes) that regulate PMN transepithelial migration and also suggest that JAM-C ma

26 ularly L-kynurenine, directly suppressed PMN transepithelial migration and induced an attached, sprea

27 dd a new element to a multistep model of PMN transepithelial migration and may provide new targets fo

28 a novel mechanism for the regulation of PMN transepithelial migration and may suggest a new therapeu

29 ulted in reduced polymorphonuclear leucocyte transepithelial migration and mitogen-activated protein

30 stic features of bacteria-induced neutrophil transepithelial migration and other important immunologi

31 lays a well-described role in regulating PMN transepithelial migration and PMN inflammatory functions

32 results that epithelial hypoxia enhances PMN transepithelial migration and promotes apical clearance

33 tivation of the PMN RvE1 receptor attenuates transepithelial migration and subsequent actions on the

34 A transepithelial migration assay was used to study the mi

35 ase pathways and polymorphonuclear leucocyte transepithelial migration associated with Shigella invas

36 on to entactin; and PMN transendothelial and transepithelial migration at a step subsequent to tight

37 necessary for germ cell dispersal and proper transepithelial migration at the onset of migration and

38 In assays of PMN transepithelial migration, both JAM-C mAbs and JAM-C/Fc

39 to small solutes occurred in the absence of transepithelial migration but required both PMN contact

40 inhibition of epithelial-T cell adhesion and transepithelial migration by anti-RANTES mAbs.

41 cytosolic acidification) enhanced neutrophil-transepithelial migration by approximately 70%.

42 ificant role in infection-induced neutrophil transepithelial migration by mediating LTB4 synthesis du

43 utant of S. flexneri resulted in reduced PMN transepithelial migration compared to infection by the w

44 trophil (polymorphonuclear leukocytes [PMN]) transepithelial migration during inflammatory episodes i

45 High-density PMN transepithelial migration for 70-110 minutes produced mu

46 of Pseudomonas aeruginosa-induced neutrophil transepithelial migration has not been explored.

47 hemerin (peptide agonist of ChemR23) reduced transepithelial migration in a concentration-dependent m

48 Neutrophil adhesion and transepithelial migration in asthma patients were associ

49 ous proinflammatory responses and neutrophil transepithelial migration in response to an experimental

50 PMN transepithelial migration in response to infection with

51 uced neutrophil chemoattractant that directs transepithelial migration in response to infection.

52 of host signaling pathways required for PMN transepithelial migration in Shigella and EPEC infection

53 erm cell dispersal but is not sufficient for transepithelial migration in the absence of Tre1.

54 2-LOX pathway prevented pathogen-induced PMN transepithelial migration in vitro and dramatically redu

55 his enzyme blocked S. pneumoniae-induced PMN transepithelial migration in vitro Genetic ablation of t

56 Analysis of transepithelial migration in vitro suggested that SLS in

57 was impaired in triggering human neutrophil transepithelial migration in vitro.

58 t potently suppresses IL-8-driven neutrophil transepithelial migration in vitro.

59 s of EAEC, was required for EAEC-induced PMN transepithelial migration in vitro.

60 ithelial PMN migration, the direction of PMN transepithelial migration in vivo.

61 Late events, occurring during actual PMN transepithelial migration, included redistribution of ep

62 Our in vitro model enables blood neutrophil transepithelial migration into cell-free tracheal aspira

63 sation from the blood vessel or during their transepithelial migration into the airways.

64 on polymorphonuclear neutrophil (PMNs) after transepithelial migration into the alveolar space.

65 that the Cxcl1/Cxcr2 axis drives neutrophil transepithelial migration into the vagina.

66 perturbing monolayer continuity, neutrophil transepithelial migration is associated with a window of

67 Neutrophil (PMN) transepithelial migration is dependent on the leukocyte

68 eutrophil (polymorphonuclear leukocyte, PMN) transepithelial migration is dependent on the leukocyte

69 Instead, PMN transepithelial migration is mediated by the eicosanoid

70 We propose that regulation of PMN transepithelial migration is mediated, in part, by seque

71 Lastly, in assays of PMN transepithelial migration, JAML/CAR fusion proteins and

72 Following hepoxilin A3-driven transepithelial migration, neutrophil chemotaxis is ampl

73 ignificantly increased apical-to-basolateral transepithelial migration of bacteria.

74 The transepithelial migration of Escherichia coli that expre

75 free, HIV-1 transmission occurs, mediated by transepithelial migration of HIV-infected cells.

76 and Tlr4(-/-)Tlr2(-/-) mice showed impaired transepithelial migration of inflammatory cells but decr

77 by disease flares that are characterized by transepithelial migration of neutrophils (PMN) and alter

78 Transepithelial migration of neutrophils (PMN) is a defi

79 nflammatory responses that result in massive transepithelial migration of neutrophils across the inte

80 all intestine, eliciting the recruitment and transepithelial migration of neutrophils and inflammator

81 We also measured ex vivo transepithelial migration of neutrophils from sham, B, E

82 l stimulation by A. fumigatus to promote the transepithelial migration of neutrophils from the basola

83 that TREM-1 also plays an important role in transepithelial migration of neutrophils into the airspa

84 rized by active inflammation associated with transepithelial migration of neutrophils may, paradoxica

85 l defense remains unknown.To investigate the transepithelial migration of neutrophils, we used adopti

86 llular calcium mobilization, chemotaxis, and transepithelial migration of neutrophils.

87 kely to be responsible for the final step of transepithelial migration of PMN and entry into the apic

88 attachment to T84 monolayers stimulated the transepithelial migration of PMN in a dose-dependent fas

89 icient to explain the observed final step of transepithelial migration of PMN induced by Salmonella-a

90 While transepithelial migration of PMN was markedly inhibited

91 The transepithelial migration of polymorphonuclear leukocyte

92 ammation of the intestine is associated with transepithelial migration of polymorphonuclear leukocyte

93 rminants were tested in an in vitro model of transepithelial migration of polymorphonuclear neutrophi

94 g a physiologic explanation for the observed transepithelial migration phenotype.

95 ms that underlie bacteria-induced neutrophil transepithelial migration previously characterized using

96 to induce polymorphonuclear leukocyte (PMN) transepithelial migration (protein kinase C and extracel

97 himurium-induced polymorphonuclear leukocyte transepithelial migration response in vitro by inhibitin

98 membrane failed to stimulate a directed PMN transepithelial migration response.

99 revious in vitro studies have shown that PMN transepithelial migration results in increased epithelia

100 derstanding of the mechanisms regulating PMN transepithelial migration should provide insights into c

101 However, the role of Lewis glycans during transepithelial migration (TEM) has not been well charac

102 utrophil [polymorphonuclear leukocyte (PMN)] transepithelial migration (TEM) is a hallmark of inflamm

103 PMN transepithelial migration (TEM) is a multistep process t

104 N-linked glycan Lewis X on CD11b blocks PMN transepithelial migration (TEpM).

105 anced co-culture model to explore neutrophil transepithelial migration utilizing airway mucosal barri

106 Impaired transepithelial migration was accompanied by a lack of b

107 DEL-1 modulation of neutrophil adhesion and transepithelial migration was examined in a co-culture m

108 chanisms for triggering the induction of PMN transepithelial migration, we found that their reliance

109 dimensional real-time dynamics of neutrophil transepithelial migration, were applied.

110 The process of PMN transepithelial migration, while dependent on the neutro