ライフサイエンスコーパス: transformed cell line

1 vels to suppress cellular proliferation in a transformed cell line.

2 in the presence of RI and is cytotoxic to a transformed cell line.

3 l cell line (NRKE) to obtain a conditionally transformed cell line.

4 er hypermethylation of 5 to 10 genes in each transformed cell line.

5 r originally isolated in revertants of H-ras-transformed cell lines.

6 ctivate TGF-beta2 promoter in normal and Akt-transformed cell lines.

7 ilable for study are restricted generally to transformed cell lines.

8 solubilized MHC molecules purified from EBV-transformed cell lines.

9 receptor agonist-induced cell death in a few transformed cell lines.

10 h the nuclear matrix in viral- and non-viral transformed cell lines.

11 alpha and reduces hypoxic gene expression in transformed cell lines.

12 PP) inhibits chemotactic motility of several transformed cell lines.

13 ic crisis followed by the emergence of fully transformed cell lines.

14 They are also expressed in many transformed cell lines.

15 in the major fraction of tumors and in many transformed cell lines.

16 fibroblasts, smooth muscle cells, or several transformed cell lines.

17 normal human tissues but not in malignantly transformed cell lines.

18 studies that previously have been limited to transformed cell lines.

19 nd STRL33/BONZO/TYMSTR and GPR15/BOB HOS.CD4 transformed cell lines.

20 peripheral blood mononuclear cells and some transformed cell lines.

21 any human tumors as well as v-abl- and v-src-transformed cell lines.

22 the 1.9-kb Survivin transcript expressed in transformed cell lines.

23 distension and eventual death of a number of transformed cell lines.

24 itutive phosphorylation is not seen in v-fgr-transformed cell lines.

25 at rapidly induces apoptosis in a variety of transformed cell lines.

26 lls, resulting in the efficient formation of transformed cell lines.

27 iocarcinomas we studied, and in a variety of transformed cell lines.

28 tion in the virally transformed and oncogene-transformed cell lines.

29 fe of the TGFalpha transcript in the various transformed cell lines.

30 ems with the facile in vitro manipulation of transformed cell lines.

31 ed those previously documented in permissive transformed cell lines.

32 enous PPP methylation in transformed and non-transformed cell lines.

33 regulatory subunit binding in cancer and non-transformed cell lines.

34 ments to localize to virological synapses in transformed cell lines.

35 3rd passage as well as the primary and virus-transformed cell lines.

36 lity to CD3/28 costimulated T cells and some transformed cell lines.

37 ion candidates in 22 breast cancer and 9 non-transformed cell lines.

38 in other skin-derived cell immortalized and transformed cell lines.

39 OCS1 in both transfected cells and in HTLV-1-transformed cell lines.

40 ontamination of retroviral vectors made from transformed cell lines.

41 region (TPR) in Tax-immortalized and HTLV-I-transformed cell lines.

42 ibian epithelial cells, neurons, and several transformed cell lines.

43 tagged RECQL4 are nuclear and cytoplasmic in transformed cell lines.

44 on but down-regulated in primary cancers and transformed cell lines.

45 responsible for oncogenic malignancy in the transformed cell lines.

46 single splice form of Ca(v)3.2 expressed in transformed cell lines.

47 extracts of both nontransformed and oncogene-transformed cell lines.

48 with those from populations of independently transformed cell lines.

49 human tumors as well as in v-abl- and v-src-transformed cell lines.

50 ate to low levels of TMEFF1 in most of these transformed cell lines.

51 protein whose expression was lost in virally transformed cell lines.

52 ociated with telomere length in DNA from EBV-transformed cell-lines.

53 Stimulation was seen for both transformed cell lines (293T and HeLa cells) and primary

54 dermal JB6 cells and the corresponding H-ras-transformed cell line 30.7b Ras 12.

55 e in animals, we characterized a variant ras-transformed cell line, 749r-1, which was resistant to ph

56 decrease in the growth rate of many putative transformed cell lines after 6 weeks of culturing in sel

57 The transformed cell line alphaAalphaBKO1 derived from alpha

58 nd by antigen presentation using a Theileria-transformed cell line and autologous T cells from Theile

59 horylation has also been observed in various transformed cell line and in primary malignant tissue, s

60 differences in genomic R-loop formation in a transformed cell line and intact tissue.

61 ells were restimulated in vitro with the EBV transformed cell line and tested for cytolytic activity.

62 the experimental design that includes a non-transformed cell line and three tumorigenic cell lines,

63 Transformed cell lines and animal models have been widel

64 d development is that they rely primarily on transformed cell lines and animal models that substantia

65 iruses because HRV growth is limited in most transformed cell lines and animal models.

66 he abnormal clones, Epstein-Barr virus (EBV)-transformed cell lines and CD34+ cells were analyzed fro

67 y induces apoptosis of Tax expressing HTLV-1-transformed cell lines and CD4 + T cells from HAM/TSP pa

68 in (E555K) was stable in patient-derived EBV-transformed cell lines and cell lines transfected with e

69 sine triphosphate (GTP) in untransformed and transformed cell lines and determine this phenomenon dep

70 The combination of peptide binding to EBV-transformed cell lines and DQ transgenic mice provides a

71 In these reports, transformed cell lines and drug-selected cells have been

72 PRKX gene in 12 different human tissues and transformed cell lines and found that, among these tissu

73 ide range of tumor cells as well as in vitro-transformed cell lines and has been implicated as a new

74 i in seven diverse cell lines, including six transformed cell lines and human induced pluripotent ste

75 s are expressed at varying levels in all the transformed cell lines and human tumors tested, further

76 r, survivin becomes prominently expressed in transformed cell lines and in all the most common human

77 rtial or complete peroxisome loss in several transformed cell lines and in fibroblasts derived from a

78 rotein that is absent or inactive in several transformed cell lines and lung tumors.

79 (HDACis) on HIV reactivation in established transformed cell lines and primary CD4(+) T cells.

80 ed to determine how HDACis reactivate HIV in transformed cell lines and primary cells.

81 These cell types include transformed cell lines and primary hematopoietic progeni

82 Here, using both transformed cell lines and primary neurons, we investiga

83 5(-/-)/VpreB1(-/-)/VpreB2(-/-) Abelson virus-transformed cell lines and reconstituted these cells wit

84 q/G11 protein was extracted from control and transformed cell lines and reconstituted with exogenous

85 r human T-cell leukemia virus type 1 (HTLV1)-transformed cell lines and results in apoptosis and redu

86 In many virus-transformed cell lines and spontaneous tumours, these ge

87 CCR1, CCR2b, CCR3, CCR5, and CXCR4 U87MG.CD4 transformed cell lines and STRL33/BONZO/TYMSTR and GPR15

88 -STAT complexes were detected in all Bcr/Abl-transformed cell lines and they were supershifted by ant

89 ability to protect against extinction in the transformed cell lines and to function as a chromatin bo

90 ercaptopropanol induced apoptosis in several transformed cell lines and transformed primary cultures

91 A few transformed cell lines and two historic strains have bee

92 HRVs, as they generally replicate poorly in transformed cell lines, and host range restriction preve

93 r, these reports almost exclusively utilized transformed cell lines, and many employed transfection o

94 TLV-1 isolates derived from primary sources, transformed cell lines, and molecular clones.

95 e kinase overexpressed in many human tumors, transformed cell lines, and rapidly proliferating tissue

96 modification is defective in many tumors and transformed cell lines, and the extent of hypomodificati

97 up-regulated in various types of tumors and transformed cell lines, and the overexpression of COX-2

98 ects tumor growth in these two sets of H-ras-transformed cell lines, and this negative effect is not

99 However almost all of these studies utilized transformed cell lines, and thus the involvement of othe

100 ssed in adult and embryo-derived stem cells, transformed cell lines, and tumors.

101 In addition, the atx-transfected ras-transformed cell lines appeared to produce tumors that w

102 In addition to altered physiology, transformed cell lines are composed of a single cell typ

103 These L. monocytogenes-infected Qa-1b-transformed cell lines are lysed by BALB/c (Qa-1b)- or C

104 lls, mesenchymal stem cells, fibroblasts and transformed cell lines, as well as a method for identify

105 o virus replication and apoptosis in several transformed cell lines, as well as to replication and pa

106 mtrII-transformed cell lines, at both early and late passage,

107 s in transformed cells using a Kirsten virus-transformed cell line (ATCC NRK1569) as a model system.

108 ylation studies are currently performed from transformed cell lines because of the ability to generat

109 ild-type and HM175/P16 viruses in two stably transformed cell lines (BT7-H and FRhK-T7) which constit

110 ce apoptosis in a variety of tumorigenic and transformed cell lines but not in many normal cells.

111 assembly were linked in three different ras-transformed cell lines but not in SV40- or RSV-transform

112 toxic protein that induces apoptosis of many transformed cell lines but not of normal tissues, even t

113 xport of prohibitin occurs preferentially in transformed cell lines, but not in untransformed or prim

114 lysates from human Epstein-Barr virus (EBV)-transformed cell lines by immunoblot analysis.

115 e of cell types, including primary cells and transformed cell lines, by as much as 10(4)-fold.

116 uppression, whereas the human papillomavirus-transformed cell lines, CaSki and HeLa, did not.

117 Transformed cell lines containing the exogenous M or R e

118 performed with a panel of nontransformed and transformed cell lines cultured at 37 and 39.5 degrees C

119 Compared with other transformed cell lines, cultured iCSCL-10A cells exhibit

120 Measurement of mRNA decay rates in stably transformed cell lines demonstrated that premature nonse

121 In these cells and transformed cell lines, depletion of Hili increased leve

122 undation for this system is an Abelson virus-transformed cell line derived from RAG-1(-/-) mice that

123 5 and into MRC-SV1, a simian virus 40 (SV40)-transformed cell line derived from them.

124 Mouse embryonic stem (ES) cells are non-transformed cell lines derived directly from the pluripo

125 Cells of renal or intestinal origin and transformed cell lines derived from breast, stomach, bon

126 and this effect appears to be restricted to transformed cell lines derived from the early stages of

127 Expression analyses on 10 different human transformed cell lines detect exclusive XYLT2 expression

128 is surrounded by insulator elements, stably transformed cell lines display consistent enhancer-depen

129 e, we show that natural target cells but not transformed cell lines downregulate the YTH Domain Famil

130 We report that EBV-transformed cell lines, EBV-lymphoma cell lines, and EBV

131 dical center, we analyzed Epstein-Barr virus-transformed cell lines established from peripheral blood

132 In transformed cell lines established from the primary cell

133 overexpressed in certain tumor types and all transformed cell lines examined.

134 EBV(+) lymphomas and transformed cell lines exhibited abundant expression of

135 ll lines investigated, while the other three transformed cell lines exhibited loss of USF2 activity.

136 NF-kappaB) in the prevention of apoptosis in transformed cell lines exposed to tumor necrosis factor

137 ffects of SSeCKS, we developed conditionally transformed cell lines (expressing ts72v-src) with tetra

138 The FMR1 origin is active in transformed cell lines, fibroblasts from healthy individ

139 on in both human and murine immortalized and transformed cell lines following induction of wild-type

140 t shock could be observed in simian virus 40 transformed cell lines from human TM.

141 Spontaneous transformed cell lines from Ku703A/3A mice are more radi

142 WASP was present in two of four EBV-transformed cell lines from WAS patients.

143 Expression of the USP transcripts in MDV-transformed cell lines further substantiates this hypoth

144 The transformed cell line grew tumors when injected subcutan

145 AA also inhibited growth of the bcr-abl-transformed cell line H7.bcr-abl A54.

146 No transformed cell line had only the LMP1 delta185-211 gen

147 The transformed cell line has been maintained for over 30 ge

148 Moreover, EGF-R-transformed cell lines have constitutive EGF-R activity,

149 s, worms, mammalian embryonic stem cells and transformed cell lines have found well-positioned nucleo

150 v-Rel-transformed cell lines have longer telomeres than untran

151 Abelson murine leukemia virus-transformed cell lines have provided a critical model sy

152 loser to those in transfected cells and some transformed cell lines, hsp70 is continuously bound by B

153 urine astrocytes and neurons, and in several transformed cell lines (human (SH-SY5Y) and murine (N1E-

154 osure to lysates or supernatants of necrotic transformed cell lines, human dendritic cells (DCs) unde

155 f 5-methylcytosine RNA methyltransferases in transformed cell lines, identified that the NOL1/NOP2/Su

156 d by their ability to slow the growth of ras transformed cell lines in soft agar.

157 und when primary isolates adapt to growth in transformed cell lines in vitro has little to do with al

158 ected B cells generate neoplasms in vivo and transformed cell lines in vitro.

159 The AGLCL Epstein-Barr virus (EBV) growth-transformed cell line is incapable of inducing tumors in

160 ressor activity, and phenotypic reversion of transformed cell lines is accompanied by increased lysyl

161 demonstrate that the wild-type p53 in HTLV-1-transformed cell lines is not fully active.

162 ibition by farnesyl-transferase inhibitor in transformed cell lines is overcome by ectopic expression

163 Furthermore, in the Bcr-Abl transformed cell line, K562 endogenous GCKR and CrkL coi

164 Oncogenically-transformed cell lines lack localization-resets and inst

165 er IL-2 stimulation of an Epstein-Barr virus-transformed cell line (LCL) from an X-SCID patient with

166 e inhibition of telomerase activity in v-Rel-transformed cell lines led to apoptosis within 24 h.

167 ssion is downregulated in breast cancers and transformed cell lines making it an attractive marker fo

168 A transformed cell line (MDB) was exposed to microsomes pr

169 owth and cytoskeletal functions in a BCR-ABL-transformed cell line model was investigated.

170 1 by RNA-mediated interference in the HTLV-1-transformed cell line MT-2 resulted in increased IFN-bet

171 ere obtained for both blood (N = 24) and EBV-transformed cell-line (N = 36) DNA samples from men aged

172 e 7 had no effect on SARS-CoV replication in transformed cell lines, nor did it alter the induction o

173 ARPE-19 is a spontaneously transformed cell line of human RPE that is widely studie

174 y in cells originated from malignant tumors: transformed cell line of non-cancer origin, HEK293, was

175 Screening more than 100 EBV-transformed cell lines of GC origin identified 6 lines l

176 nd effects of TFIIB knockdown in primary and transformed cell lines on cellular functionality and glo

177 In neurons and transformed cell lines, opioid receptors are coupled to

178 In contrast, DCs exposed to apoptotic transformed cell lines or necrotic lysates of primary ce

179 EBNA2 and EBNA-LP was not detectable in EBV-transformed cell lines or transfected type I Burkitt's c

180 o-2 cell lines but not in HT-29, T84, SW-480 transformed cell lines, or native colonic epithelial cel

181 The transformed cell lines outperformed the primary and SV40

182 Stably transformed cell lines overexpressing a dominant negativ

183 Transformed cell lines producing foreign proteins were r

184 nd the expression of miR-302a in primary and transformed cell lines promotes an increase in S-phase a

185 This contrasts with the Tax-transformed cell lines, PX1 (fibroblast) and MT4 (lympho

186 t to be substrate-driven, studies in several transformed cell lines reported that glucose deprivation

187 ncogenic Ras up-regulates autophagy, and Ras-transformed cell lines require autophagy for mitochondri

188 expression of Dab2 in F9 cells as well as in transformed cell lines results in increased Axin express

189 the proteasome by EGCG in several tumor and transformed cell lines results in the accumulation of tw

190 Comparison to analogous data from transformed cell lines revealed respiratory-specific pro

191 In 2001, a transformed cell line RGC-5 was developed from the rat r

192 Experiments were carried out with an SV40 transformed cell line (rMC-1) that exhibits the phenotyp

193 The transformed cell lines show increased expression of matr

194 Analysis of supernatants of necrotic transformed cell lines showed them to be enriched in the

195 are consistently elevated in EBV- and HTLV1-transformed cell lines stably expressing shIRF4.

196 In many human cancers and transformed cell lines, Stat3 is persistently activated,

197 In addition to commonly used transformed cell lines such as HeLa, CHO, Cos-7, and 293

198 0- to 100-fold-less infectious than rAAV2 in transformed cell lines (such as HEK-293, HeLa, and CV1-T

199 Several earlier studies in transformed cell lines suggested that normoxic stabiliza

200 ephosphorylation of GAPa-p62 is defective in transformed cell lines, suggesting a possible role for p

201 ly in plasmid transfection assays in several transformed cell lines, suggesting that the cis-regulato

202 Its expression in fetal liver and in transformed cell lines suggests CRD-BP is an oncofetal p

203 essing viral proteins but not with an HTLV-1-transformed cell line that does not express viral protei

204 human T-cell leukemia virus type 1 (HTLV-1)-transformed cell lines that are permissive for HIV-1 rep

205 infection, researchers have frequently used transformed cell lines that can have limited translation

206 In order to propagate this mutant virus, transformed cell lines that express the UL37 gene produc

207 o move away from the often nonphysiological, transformed cell lines that have been used for decades i

208 In contrast all stable transformed cell lines that were tested, derived either

209 One of these transformed cell lines, the A-U3 cell line, was evaluate

210 nto the bioenergetic states of progressively transformed cell lines, the effect of oncogenes on small

211 sal levels of adhesion through L-selectin in transformed cell lines, the rapid increase in ligand bin

212 ment, in cancers, and in immortalized and/or transformed cell lines, the significance of which is unc

213 cromolar concentrations, induce a variety of transformed cell lines to differentiate.

214 Virus propagation methods generally use transformed cell lines to grow viruses from clinical spe

215 show that the effect of exposure of several transformed cell lines to metformin varies with carbon s

216 alpha was not due to an inability of BCR/ABL-transformed cell lines to migrate in general, as spontan

217 al cells demonstrated relatively low levels (transformed cell line) to high levels (primary cell line

218 In T cells and transformed cell lines used as model systems, HIV-1 asse

219 ificant changes between the immortalized and transformed cell lines using peptide mass fingerprinting

220 o frameshift mutations in Epstein Barr virus-transformed cell lines, using reverse-transcriptase poly

221 A transformed cell line was generated from these primary c

222 PKABA1 produced in transformed cell lines was able to phosphorylate synthet

223 Cp usage in the HVP- and RhEBV-transformed cell lines was detected by S1 nuclease prote

224 o directly analyze whether the p53 in HTLV-1-transformed cell lines was transcriptionally active and

225 In a K-ras transformed cell line we experimentally assessed glutami

226 e why EBV infected blasts go on to establish transformed cell lines, we performed global transcriptom

227 Applying MAGIC to near-diploid, non-transformed cell lines, we track de novo CAs over succes

228 In this study, we show that when BCR-ABL-transformed cell lines were selected for imatinib resist

229 samples of a panel of mouse immortalized or transformed cell lines were shown to express abundant le

230 ies of immortalized and human papillomavirus-transformed cell lines were used to demonstrate that the

231 target cell types, but not in commonly used transformed cell lines wherein the control of YTHDF2 exp

232 v-ErbB:ER construct and these conditionally transformed cell lines will be useful to further elucida

233 d with wild-type CSB (CS-B wt), and a stably transformed cell line with a point mutation in the ATPas

234 Finally, treatment of HTLV-1-transformed cell lines with 17-DMAG suppressed HTLV-1 re