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2 tocrine/paracrine release of the EGFR ligand transforming growth factor alpha in a TACE-dependent man
4 erase (GLuc), epidermal growth factor (EGF), transforming growth factor-alpha (TGF-alpha) and epiregu
5 bed chimeric Galpha subunit activation via a transforming growth factor-alpha (TGF-alpha) shedding re
7 ach to characterize the robustness of gurken/transforming growth factor-alpha mRNA localization in Dr
8 al interactions of the Notch ligand DLL4 and transforming growth factor-b (TGF-beta) family ligands p
9 athways govern epithelial proliferation, and transforming growth factor beta (TGF-beta and BMP signal
12 that during immune homeostasis, the cytokine transforming growth factor beta (TGF-beta) epigeneticall
15 phiregulin functioned by releasing bioactive transforming growth factor beta (TGF-beta) from latent c
16 d reduced the levels of interferon gamma and transforming growth factor beta (TGF-beta) in mice with
19 earch suggests that profibrotic signaling by transforming growth factor beta (TGF-beta) is directly t
24 in (BMP) Receptor-1A as OAC but only 1/12 of Transforming Growth Factor beta (TGF-beta) Receptor-1.
25 to myofibroblasts through hyperactivation of transforming growth factor beta (TGF-beta) signaling in
26 clerosis, hypercholesterolemia, and abnormal transforming growth factor beta (TGF-beta) signaling in
29 lin-like (insulin/IGF-1 signaling [IIS]) and transforming growth factor beta (TGF-beta) signaling rep
30 d medullary keratinocytes, guided by Bmp and transforming growth factor beta (TGF-beta) signaling tha
31 rominent function of TGIF1 is suppression of transforming growth factor beta (TGF-beta) signaling, wh
32 lial homing alpha-E integrin (CD103) through transforming growth factor beta (TGF-beta) signaling.
34 epsilonRIalpha(+) macrophages send paracrine transforming growth factor beta (TGF-beta) signals to TI
35 ts indicate that CREB acts downstream of the transforming growth factor beta (TGF-beta) Sma/Mab pathw
36 virions binds the immunosuppressive cytokine transforming growth factor beta (TGF-beta) through a lig
37 d important cellular pathways like STAT1 and transforming growth factor beta (TGF-beta) to be differe
38 of the cytokines interleukin (IL)-6, IL-10, transforming growth factor beta (TGF-beta), and interfer
39 y modulating fibroblast growth factor (FGF), transforming growth factor beta (TGF-beta), and WNT path
40 the prototypical prosclerotic growth factor, transforming growth factor beta (TGF-beta), is thought t
41 d by inducible nitric oxide synthase (iNOS), transforming growth factor beta (TGF-beta), NADPH oxidas
44 ic regulation of lipid metabolism, involving transforming growth factor beta (TGF-beta)-regulated pho
45 (RNA-seq) and lineage tracing, we found that transforming growth factor beta (TGF-beta)-responding tS
49 chondrogenic differentiation by influencing transforming growth factor beta (TGF-beta)/SMAD family 2
50 ollagen remains poorly understood apart from Transforming Growth Factor beta (TGF-beta1)-mediated ind
51 for fibrillin-1 in regulating extracellular transforming growth factor beta (TGFB) bioavailability a
52 M) family, which interact with microbes, and transforming growth factor beta (TGFB) signaling pathway
53 and was found to activate complex of latent transforming growth factor beta (TGFbeta at the surface
57 trogen-mediated uterine functions, including transforming growth factor beta (TGFbeta) and LIF interl
61 eterozygous, loss-of-function mutations in 4 transforming growth factor beta (TGFbeta) pathway member
64 identified progesterone receptor action and transforming growth factor beta (TGFbeta) signaling via
67 (BMPs) are multifunctional cytokines of the transforming growth factor beta (TGFbeta) superfamily wi
68 were treated with the pro-scarring cytokine, transforming growth factor beta (TGFbeta) to induce coll
70 Instead, the transcription factor Twist1, transforming growth factor beta (TGFbeta), and YAP activ
71 in (IL6) beta2SP(+/-) LSCs was activated by transforming growth factor beta (TGFbeta)-activated kina
72 modular glycoprotein that includes 7 latent transforming growth factor beta (TGFbeta)-binding protei
73 ates with SMAD3 to modulate transcription of transforming growth factor beta (TGFbeta)-dependent gene
74 ) and lipoma-preferred partner (LPP) mediate transforming growth factor beta (TGFbeta)-induced breast
75 ion are consistent with dysregulation of the transforming growth factor beta (TGFbeta)/bone morphogen
76 ood allergy (FA) had decreased expression of transforming growth factor beta 1 (TGF-beta1) because of
77 eloid cells, which reduced the production of transforming growth factor beta 1 (TGF-beta1), a cytokin
79 okines produced by T-helper type 2 cells and transforming growth factor beta 1 (TGFbeta1) contribute
80 e subclass expressed many genes regulated by transforming growth factor beta 1 that mediate immunosup
81 the likely effector genes, including TGFB1 (transforming growth factor beta 1), FGF18 (fibroblast gr
82 ystatin B, the latency-associated peptide of transforming growth factor beta 1, oxidized low-density
83 r 1 (HIF-1), monocyte chemotactic protein 1, transforming growth factor beta 1, TIR-domain containing
85 XA1 loss leads to remarkable upregulation of transforming growth factor beta 3 (TGFB3), which encodes
86 yte-macrophage colony-stimulating factor and transforming growth factor beta alone, whereas CD14(+) c
87 ificantly higher profibrotic pathway levels (transforming growth factor beta and collagen-1) than in
88 -inflammatory upstream regulators, including transforming growth factor beta and interleukin 10 recep
90 mouse embryonic fibroblasts and T cells with transforming growth factor beta increased their producti
92 ed NTHi infection up to 3 days increased the transforming growth factor beta levels, decreasing the e
93 ugh the SMAD2 transcription modulator of the transforming growth factor beta pathway, which activates
95 regulated expression of alphaSMA, PDGFbetaR, transforming growth factor beta receptor 1 (TGFbetaR1),
96 we characterize the biologic effects of two transforming growth factor beta receptor 1 (TGFBR1) kina
97 es in this study suggests that activation of transforming growth factor beta signaling and epithelial
98 anisms of pathogenesis centered on disrupted transforming growth factor beta signaling and hippocampa
100 translocation of SMAD7 and thereby decreases transforming growth factor beta signaling in T cells.
101 biopsies from MS patients revealed decreased transforming growth factor beta signaling with a shift t
102 esion, epithelial-to-mesenchymal transition, transforming growth factor beta signaling, maintenance o
104 ppress the immune response and activation of transforming growth factor beta signaling; or expression
105 ept, a recombinant fusion protein that binds transforming growth factor beta superfamily ligands to r
106 ombinant fusion protein that binds to select transforming growth factor beta superfamily ligands, may
107 ntiation factor 8 (GDF8)) is a member of the transforming growth factor beta superfamily of growth fa
109 lowing isotropic chondrogenic induction with transforming growth factor beta to set up a dual-compart
110 nal pathways of activation, such as TGFbeta (transforming growth factor beta) and AngII (angiotensin
111 cues with the profibrotic agonist, TGFbeta (transforming growth factor beta), additively upregulated
112 erived growth factor BB, and unresponsive to transforming growth factor beta, a prominent cytokine of
113 actor kappa B, interleukin-6, interleukin-8, transforming growth factor beta, and vascular endothelia
114 h as proliferation-progenitor, proliferation-transforming growth factor beta, and Wnt-catenin beta1.
115 ctin, and the latency-associated peptides of transforming growth factor beta, in a MIDAS/cation-indep
116 g of concurrent reduced quantities of active transforming growth factor beta, while mucosal IgM is si
117 protein that uniquely associates with latent transforming growth factor beta-1 (TGF- beta1) and ancho
122 critical elements of fibrogenesis, including transforming growth factor beta-1-SMAD3 activation, prod
123 (BA) abnormalities, we find that microglial transforming growth factor beta-activated kinase 1 (Tak1
124 ted kinase-1 (IRAK-1) and IRAK-4, as well as transforming growth factor beta-activated kinase 1 (TAK1
125 ng disorders such as Alzheimer's disease and transforming growth factor beta-induced protein (TGFBIp)
127 2(-/-) HSCs, defects were identified in each transforming growth factor beta/Smad2/3 and ET-1/Erk1/2
128 his leads to increased T(REG) sensitivity to transforming growth factor - beta and promotes transplan
129 grin protein expression and upregulated TGF (transforming growth factor)-beta and CTGF (connective ti
132 tg16l1 deficient CD11b(+) DCs develop a TGF (transforming growth factor)-beta-dependent tolerogenic p
134 AD2 and SMAD3 are downstream proteins in the transforming growth factor-beta (TGF beta) signaling pat
136 Encoded in mammalian cells by 33 genes, the transforming growth factor-beta (TGF-beta) family of sec
137 proteins (BMPs) are secreted ligands of the transforming growth factor-beta (TGF-beta) family that c
138 17 (Th17) cell differentiation by activating transforming growth factor-beta (TGF-beta) from its late
140 uppressive function through increased active transforming growth factor-beta (TGF-beta) in Tregs sign
144 f the TGF-beta family that selectively binds transforming growth factor-beta (TGF-beta) isoforms and
145 ovine tendons, which is capable of enhancing transforming growth factor-beta (TGF-beta) mediated teno
147 ction mutations in positive effectors of the transforming growth factor-beta (TGF-beta) pathway.
148 ey also increased interleukin-10 (IL-10) and transforming growth factor-beta (TGF-beta) production an
153 of ILC1-like cells concurrent with increased transforming growth factor-beta (TGF-beta) signaling.
154 blasts requires both a mechanical signal and transforming growth factor-beta (TGF-beta) signaling.
158 ntiation factor-15 (GDF-15), a ligand in the transforming growth factor-beta (TGF-beta) superfamily,
159 this study, we investigated the role of the transforming growth factor-beta (TGF-beta) superfamily,
161 e cutaneous SSc (dcSSc); (ii) the ability of Transforming Growth Factor-beta (TGF-beta) to modulate E
162 erleukin-1 receptor antagonist (IL-1RA), and transforming growth factor-beta (TGF-beta)) with inciden
164 has been implicated in airway diseases where transforming growth factor-beta (TGF-beta)-induced epith
166 plastic BE tissues showed hyperactivation of transforming growth factor-beta (TGFB) and/or Jun N-term
167 inflammatory cues including interferons and transforming growth factor-beta (TGFbeta) cytokines.
171 wing antigen-driven expansion in lymph node, transforming growth factor-beta (TGFbeta) is required fo
172 mpathetic nervous systems, activation of the transforming growth factor-beta (TGFbeta) pathway, abnor
174 proteins upon stimulation of fibroblasts by transforming growth factor-beta (TGFbeta) play a critica
176 static regulation by multiple ligands of the transforming growth factor-beta (TGFbeta) superfamily.
178 tegrin plays a key role in the activation of transforming growth factor-beta (TGFbeta), a pro-fibroti
179 shared fibrotic signalling responses such as transforming growth factor-beta (TGFbeta), platelet-deri
180 iated with upregulation of genes involved in transforming growth factor-beta (TGFbeta), reactive oxyg
182 , and metastasis abilities of ESCC cells via transforming growth factor-beta (TGFbeta)-dependent Dros
185 receptor, WNT, receptor tyrosine kinase and transforming growth factor-beta (TGFbeta)/bone morphogen
186 tractant protein-1 (MCP-1) (0.798, p<0.005), transforming growth factor-beta 1 (1.009, p<0.05), solub
187 ophage colony-stimulating factor (M-CSF) and transforming growth factor-beta 1 (TGF-beta1) in the pre
188 report did not contrast KGN directly against transforming growth factor-beta 1 (TGF-beta1), the most
190 ns of different epitheliotropic factors (eg, transforming growth factor-beta [TGF-beta1], epidermal g
191 erleukin-1 receptor antagonist [IL-1RA], and transforming growth factor-beta [TGF-beta]), with incide
192 nockdown of PCSK6 in cardiomyocytes impacted transforming growth factor-beta activation and SMAD3 (mo
195 developments concerning the roles played by transforming growth factor-beta and platelet-derived gro
196 s in development - such as the activation of transforming growth factor-beta and the deposition of ex
197 ein previously shown to interact with latent transforming growth factor-beta binding protein 1 and in
198 rs, angiopoietin-2, thrombospondin-2, latent transforming growth factor-beta binding protein-4, and f
200 naling in epithelial-mesenchymal transition, transforming growth factor-beta interacted with Panx3 by
203 of the mitogen-activated protein kinase and transforming growth factor-beta pathways in Exoc5 knockd
204 ency-associated protein associated with Treg transforming growth factor-beta production and presentat
205 3(+) regulatory T cells (Tregs) and enhanced transforming growth factor-beta production by CD4(+) T c
207 [FGF21], alphaKlotho, soluble form of mouse transforming growth factor-beta receptor 2 [sTGFbetaR2])
210 ondrial function and autophagy and decreased transforming growth factor-beta signaling and activity o
213 of additional pathways, such as induction of transforming growth factor-beta signaling in BRAF melano
214 cell cycle, angiogenesis, inflammation, and transforming growth factor-beta signaling in tumor blood
215 sregulation of ephrin-receptor signaling and transforming growth factor-beta signaling pathways.
218 on of BMPR2, which encodes a receptor in the transforming growth factor-beta superfamily, the develop
223 molecular markers of fibrosis (collagen and transforming growth factor-beta) and immunostaining for
225 kappaB (nuclear factor kappaB), and TGFbeta (transforming growth factor-beta) pathways, which were va
227 t BRD4 functions as an effector of TGF-beta (transforming growth factor-beta) signaling to stimulate
228 eukin-12 [IL-12], IL-23, IL-6, IL-27, IL-10, transforming growth factor-beta) that expand and differe
229 in cardiac fibroblasts as well as TGF-beta (transforming growth factor-beta)-activated myofibroblast
232 reased, whereas tumor necrosis factor-alpha, transforming growth factor-beta, and fibrosis were remar
234 also decreased the expression of TGF-beta1 (transforming growth factor-beta-1) and CTGF (connective
235 cytokines by interacting with and inhibiting transforming growth factor-beta-activated kinase 1 (TAK1
236 ed protein kinase (MAPK) via a non-canonical transforming growth factor-beta-activated protein kinase
237 ermeability was preceded by an activation of transforming growth factor-beta-activating kinase-1 (TAK
239 o induce Cox-2 in fibroblasts and to inhibit transforming growth factor-beta-induced alpha-SMA expres
240 Mechanistically, sphingosine ameliorates transforming growth factor-beta-induced collagen accumul
243 de was further designed for the detection of transforming growth factor beta1 (TGF-beta1) protein in
244 riggered by tumour cell-derived factors like transforming growth factor beta1 (TGF-beta1), myofibrobl
248 HDAC8 siRNA was also effective in inhibiting transforming growth factor beta1 (TGFbeta1)-induced deac
249 0, and CD86) and anti-inflammatory cytokine (transforming growth factor beta1 [TGF-beta1]) were suppr
250 e reveal widespread translational effects of transforming growth factor beta1 and define novel posttr
251 al cellular reactions including secretion of Transforming Growth Factor beta1 ubiquitously in a laten
253 rganization, or being connected to TGFbeta1 (transforming growth factor beta1), interleukin-1, TNF-al
254 otide-resolution translatome data during the transforming growth factor beta1-driven cellular transit
256 inical benefits of global inhibition of TGF (transforming growth factor)-beta1 signaling remain contr
258 /-) (alias Abcb4(-/-)) mice through enhanced transforming growth factor-beta1 (TGF-beta1) biliary sec
260 lation of mRNA expressions of Collagen I and transforming growth factor-beta1 (TGF-beta1) following t
263 vated protein kinase (ERK1/2 MAPK)-dependent transforming growth factor-beta1 (TGF-beta1) signaling t
265 PLOD2 expression is induced by hypoxia and transforming growth factor-beta1 (TGF-beta1), well-known
266 ar (fibrillar) fibronectin on the surface of transforming growth factor-beta1 (TGF-beta1)-activated h
269 ent also reduces migration and deposition of transforming growth factor-beta1 (TGFbeta1)-stimulated c
270 cells, M2 macrophages, and markedly elevated transforming growth factor-beta1 and IL-6 levels, which
271 s well as by inflammatory cytokines, whereas transforming growth factor-beta1 caused decreased expres
272 , exogenous apoptotic cells failed to induce transforming growth factor-beta1 expression or Treg accu
275 sion and epigenetic changes with and without transforming growth factor-beta1 treatment, even after c
277 ating insulin resistance, in particular, the transforming growth factor-beta1/SMAD 2/3 pathway and it
278 [erbb-b2 receptor tyrosine kinase 2], TGFB1 [transforming growth factor-beta1], AREG [amphiregulin],
279 teinase 1, platelet-derived growth factor c, transforming growth factor beta2) and inflammation (tumo
281 e, we show that, in the absence of exogenous transforming growth factor-beta2 (TGFbeta2), compared wi
282 encodes a key biliary-specific subunit of a transforming growth factor (TGF) beta activator (P = 0.0
285 from rabbit corneal fibroblasts treated with transforming growth factor (TGF) beta-1 or generated dir
286 4 and CRIS-B), and drives metastasis through transforming growth factor (TGF) beta-dependent neutroph
287 binding directly to DNA or interacting with transforming growth factor (TGF) beta-responsive SMADs.
288 y arteriovenous malformations (AVM), through transforming growth factor (TGF)-beta and angiopoietin-2
289 thasone enhanced the pro-fibrotic effects of transforming growth factor (TGF)-beta as a potential mec
290 These disorders are regulated mainly through transforming growth factor (TGF)-beta family proteins by
294 n alphavbeta8 has a major role in activating transforming growth factor (TGF)-beta, a potent inhibito
296 first documented protein known to stimulate transforming growth factor (TGF)-beta1 to -beta3 transla
297 c) mice, Smad7 transgene expression reversed transforming growth factor (TGF)-beta1 transgene-induced
299 effect of neratinib on HSC was evaluated in transforming growth factor (TGF-beta)-incubated LX-2 cel