ライフサイエンスコーパス: transitional

1 s were induced in BAFFR(-/-) mice (with only transitional 1 B cells) and not in muMT mice (lacking al

2 markably, all B cell subsets, including even transitional 1 B cells, were programed to process, prese

3 significantly reduced the numbers of B1 and transitional 1 B cells.

4 evidence that in Ly9-deficient mice splenic transitional 1, MZ, and B1a B cells are markedly expande

5 hat MZ B cell development was blocked at the transitional-1 to transitional-2-MZ precursor stage in t

6 e B cells that emerge in the spleen from the transitional-2 stage paralleling the differentiation of

7 lopment was blocked at the transitional-1 to transitional-2-MZ precursor stage in the absence of func

8 -seq) analysis reveals novel mesenchymal and transitional alveolar epithelial states unique to LAM lu

9 Finally, CD19(+)CD24(++)CD38(++) transitional and CD19(+)CD24(-)CD38(-) new memory B-cell

10 physical limit of flow boiling due to highly transitional and chaotic nature of multiphase flows as w

11 AD is accompanied by systemic expansion of transitional and chronically activated CD27(+) memory, p

12 el peripheral blood studies revealed loss of transitional and follicular B cells in severe disease an

13 s and farmers as well as differences between transitional and intensive farmers in mandibular variati

14 tes that the S4 undergoes ~3- to 5- angstrom transitional and lateral movements during depolarization

15 ne, patients had lower median percentages of transitional and mature B cells than age-matched healthy

16 BAFF is a crucial survival factor for transitional and mature B cells that acts as rheostat fo

17 Colostrum, and transitional and mature milks (25) were collected from 1

18 ncies of poly- and autoreactive new emigrant/transitional and mature naive B cells in NMOSD patients

19 ased in the patients, whereas frequencies of transitional and naive B cells were decreased.

20 We observed normalization of circulating transitional and naive B cells, reduction in PD-1(+)CD4(

21 Our results indicate that inflammatory transitional and nonclassical monocytes and CD1c+ conven

22 ctal-scaling properties already during early transitional and nonisotropic stages of the flow evoluti

23 Analysis of samples from transitional and persistent phases of infection demonstr

24 Lung function declined more rapidly among transitional and post-menopausal women, in particular fo

25 affect Golgi cisternal progression, early-to-transitional and transitional-to-late, respectively.

26 er 2013-September 2014) was considered to be transitional and was excluded.

27 ty compared to the AGB(95) , particularly in transitional and/or wet regions in tropics.

28 equencies of plasmablasts and naive, memory, transitional, and activated B cells.

29 esented by three distinct LUE regimes (high, transitional, and low).

30 ion studies showed that plasmablast, plasma, transitional, and mature naive B cells were resistant to

31 ioning across three vegetation zones: grass, transitional, and shrub in a coastal grassland.

32 y dividing the study period into 3 DES eras: Transitional (April 23, 2003, to June 30, 2004); Liberal

33 ough the optic nerve lamina region (ONLR), a transitional area containing a vascular plexus.

34 he association between Neandertals and this "transitional" assemblage has been controversial because

35 In addition, both transitional B cell and plasmablast levels were signific

36 Flow cytometry analysis of the splenic transitional B cell subsets demonstrated that MZ B cell

37 Nonetheless, CD24(hi)CD38(hi) transitional B cells (TBs) and CD24(hi)CD27(+) B cells (

38 Both cGVHD and L-aGVHD had decreased transitional B cells and increased cytolytic natural kil

39 se delta (PI3Kdelta) lead to accumulation of transitional B cells and senescent T cells, lymphadenopa

40 ed with surface acquisition of CD73 on human transitional B cells and was augmented with the AMPK ago

41 Follicular and transitional B cells are enriched in fetuses while CD69(

42 n receptor (BCR) signaling determine whether transitional B cells become marginal zone B (MZB) or fol

43 In the phase 1b study, percentages of transitional B cells decreased, naive B cells increased,

44 CD19(+)CD24(hi)CD38(hi) Immature/transitional B cells elevated in diabetic than non-diabe

45 the first time, the study reveals that human transitional B cells encompass not only transitional typ

46 both LSD1-deficient and NF-kappaB-inhibited transitional B cells failed to undergo full MZB developm

47 BAFF-mediated humoral autoimmunity, TACI(+) transitional B cells from BAFF-transgenic mice spontaneo

48 cisely downmodulated upon culture of splenic transitional B cells in the presence of BAFF.

49 d for optimal survival and TLR7 responses of transitional B cells in the spleen and was overexpressed

50 Immature/transitional B cells increase remarkably in diabetic CHC

51 ells is reduced and the frequency of CD27(+) transitional B cells is increased in patients with autoi

52 Transitional B cells must actively undergo selection for

53 An increased percentage of peripheral transitional B cells producing IL-10 has been observed i

54 CD24(high)CD38(high) transitional B cells represent cells at a key stage in t

55 decreased IgD(+)CD27(+) memory B cells while transitional B cells were increased, likely contributing

56 4(high) B10 cells, CD24(hi)CD38(hi) immature transitional B cells, and CD73(-)CD25(+)CD71(+) BR1 cell

57 ty was associated with specific expansion of transitional B cells, extrafollicular IgG2c-producing pl

58 linical use markedly reduced bone marrow and transitional B cells, which has therapeutic implications

59 memory B cells and an increased frequency of transitional B cells.

60 gnaling was reduced when compared to that in transitional B cells.

61 y have often been referred to as immature or transitional B cells.

62 secretion as was observed in healthy control transitional B cells.

63 B cells, as well as IL-10-producing CD27(+) transitional B cells.

64 ity via direct, TACI-dependent activation of transitional B cells.

65 Frequencies of CD19+CD24hiCD38hi transitional B lymphocytes (Bregs) increased from a medi

66 a trend for elevation in a CXCR5/CCR6(high) transitional B-cell cluster.

67 Bregs were identified in both the naive and transitional B-cell compartments and suppressed T-cell p

68 Recent studies highlight transitional B-cell heterogeneity as a determinant of in

69 s recent advances pointing to the peripheral transitional B-cell stage as a major juncture where tran

70 study indicates that altered distribution of transitional B-cell subsets highlights different regulat

71 his stimulatory condition, CD86 expressed by transitional B-cells was down regulated and T-cell proli

72 stric junction (residual embryonic cells and transitional basal cells).

73 e both characterized by the expansion of the transitional basal progenitor cells.

74 On ectopic expression of CDX2, these transitional basal progenitors differentiate into intest

75 lly, alterations in differentially expressed transitional basal stem cell genes result in severe thin

76 pidermal homeostasis models and suggest that transitional basal stem cells are stable states essentia

77 aring B cells were significantly enriched in transitional (before: 10.1 +/- 1.9%, after: 58.8 +/- 5.2

78 from the Oligocene of South Carolina that is transitional between raptorial archaeocete whales and mo

79 g enzyme repertoires of Schizophyllaceae are transitional between those of white rot species and less

80 10(-4) s/n/r for Hong Kong 2014 (H3N2) and a transitional bias of 2.7-3.6.

81 d microscopic damage processes, resulting in transitional brittle to semi-brittle modes under P and T

82 tiveness of a comprehensive postacute stroke transitional care (TC) management program.

83 atients receiving loop diuretics at the Yale Transitional Care Center (N=162) and (2) interventional

84 At the Yale Transitional Care Center, 31.5% of patients had hypochlo

85 ng treatment with loop diuretics at the Yale Transitional Care Center.

86 F management strategy that includes tailored transitional care for patients discharged from the ED or

87 ing patients who could benefit from tailored transitional care including early follow-up and booster

88 -based observation are not included in these transitional care initiatives.

89 enter randomized trial of a patient-centered transitional care intervention in patients with acute he

90 All 3 transitional care interventions examined were more costl

91 Transitional care is a complex process, which should add

92 Transitional care may be effective in improving short-te

93 Canada, implementation of a patient-centered transitional care model compared with usual care did not

94 for healthcare professionals to support the transitional care of AYA with allergy and/or asthma.

95 ients at high risk for delirium and tailored transitional care planning may help to maximize the func

96 s no consensus on the optimal pathway of the transitional care process and no specific data are avail

97 Transitional care service designs and implementations ar

98 Transitional care service interventions attempt to mitig

99 In older patients with HF, transitional care services are economically attractive,

100 Transitional care services should become the standard of

101 bilistic sensitivity analysis confirmed that transitional care services were preferred over standard

102 or usual care (n = 1390 patients), in which transitional care was left to the discretion of clinicia

103 sted odds ratio 1.52; 95% CI 1.19-1.95), and transitional case management (1.65; 1.36-1.99), receipt

104 linkage to HIV care (LTC) and the effect of transitional case management services.

105 tegy of topological engineering of excellent transitional catalytic materials.

106 erstitial macrophages (HLA-DR(+)CD206(-)): a transitional CD11c(+)CD16(+) cell population directly as

107 )) and concomitantly decreasing the immature transitional (CD27(-)IgD(+)CD38(+)), unswitched memory (

108 Transitional cell carcinoma (TCC) of the bladder compris

109 onsidered related to the study drug (bladder transitional cell carcinoma in the ozanezumab group and

110 distinct treatment naive tumors, a papillary transitional cell renal cell carcinoma, a duodenal carci

111 nto type-1 cells acquire pre-alveolar type-1 transitional cell state (PATS) en route to terminal matu

112 of gene regulatory programs leading to Krt8+ transitional cells and their terminal differentiation to

113 TACI(+) transitional cells from BAFF-transgenic mice are charact

114 cells, suggesting that these newly generated transitional cells play a critical role in PD-1-based im

115 clinically relevant but poorly characterized transitional cells that bridge the CCS and surrounding m

116 Transitional cells undergo extensive stretching during d

117 clustering structure for both pure cells and transitional cells with soft memberships.

118 layers, significantly increase the number of transitional cells, induce clustering of mitochondria an

119 A similar transitional columnar epithelium is present at the trans

120 Here we describe a transitional columnar epithelium with distinct basal pro

121 Tendon and bone are attached by a transitional connective tissue that is morphologically g

122 ergic ChAT-ir neurons were also found within transitional cortical areas (insular, cingulate, and pir

123 tional Survey of Acute Coronary Syndromes in Transitional Countries) registry (NCT01218776).

124 , recirculating RTEs encounter TRAs during a transitional developmental stage that facilitates tolera

125 ransition from high-biomass moist forests to transitional dry forests and woody savannah-like states.

126 opausal status was defined as nonmenopausal, transitional, early postmenopausal, and late postmenopau

127 rrestrial, floodplain, riparian, benthic and transitional ecosystems with which they connect.

128 ntensive bioenergy makes the most sense as a transitional element of the global energy mix, playing a

129 and where the position of the thoracolumbar transitional element was.

130 lium AAA ATPase, p97, a homolog of the human transitional endoplasmic reticulum ATPase (VCP/p97) prot

131 cer stem cell population in a mouse model of transitional epithelial carcinoma and uncover a novel me

132 on serves as a source of progenitors for the transitional epithelium.

133 DES use varied, from 56% in the Transitional era to 85% in the Liberal era and 62% in th

134 szkaraptor was a basal dromaeosaurid showing transitional features.

135 ) that might not reflect the geometry of the transitional field.

136 ips in the pressure-derivative curves in the transitional flow period were observed as soon as pressu

137 dynamic conductivity were observed after the transitional flow period.

138 sp. enterica genomes from human skeletons of transitional foragers, pastoralists and agropastoralists

139 ody plans was amplified by the extinction of transitional forms and obscured by convergent evolution

140 picules among sponge classes and presence of transitional forms with weakly biomineralized spicules,

141 ts suggest that stem tetrapods may have used transitional gaits(5,11) during the initial stages of la

142 evealed a disease-associated subgroup with a transitional gene expression profile intermediate betwee

143 Estuaries are transitional habitats characterized by complex biogeoche

144 ly predicted to be mediated through a common transitional, high-plasticity cell state (HPCS).

145 eveals a striking zonal architecture for the transitional hourglass that pre-patterns two cytokinetic

146 d single filaments at the outer zones of the transitional hourglass, as well as in the double ring.

147 its Bud3-interacting domain destabilizes the transitional hourglass, especially at the mother side, w

148 Controls never reached transitional HR.

149 A transitional ILC3-ILC1 population was also detected in t

150 resenting a new species, Teyujagua paradoxa, transitional in morphology between archosauriforms and m

151 There was a transitional increase in Gli-1/2 gene expression levels

152 Our analysis identifies distinct transitional intermediate states and their divergent dev

153 with shorter disease duration compared with transitional LBD (beta, -1.52; 95% CI, -2.11 to -0.93; P

154 with shorter disease duration compared with transitional LBD, and this effect is independent of Braa

155 In this study, we assessed how key transitional life events and exposure to different nutri

156 on transitions predicted others' experienced transitional likelihoods with high accuracy.

157 (PLC-PDXs) from 20 hepatoblastomas (HBs), 1 transitional liver cell tumor (TCLT), 1 hepatocellular c

158 These CX3CR1(+)SiglecF(+) transitional macrophages localized to the fibrotic niche

159 e have identified a pathological subgroup of transitional macrophages that are required for the fibro

160 Human orthologs of genes expressed by the transitional macrophages were upregulated in samples fro

161 tial requirement for NCSTN during the type 2 transitional-marginal zone precursor stage and peritonea

162 CV binding, while other B subsets, including transitional, mature naive, memory, and plasma cells, we

163 +) T cell subsets in central memory (T(CM)), transitional memory (T(TM)), and effector memory (T(EM))

164 highly differentiated CD4(+) T cells such as transitional memory (TM) and effector memory (EM) CD4(+)

165 of 0.9-, 1.1-, 1.5-, and 3.7-fold for CD4(+) transitional memory [TTM], TCM, effector memory [TEM], a

166 activation mirrored the effector and central/transitional memory CD4 T cell contribution to the pool

167 bers of islet-specific CD8(+) T cells with a transitional memory phenotype.

168 Until recently, NVRS was not known in other transitional metal dichalcogenides (TMDs), an important

169 ctronic device based on two dimensional (2D) transitional metal dichalcogenides (TMDs), finding a low

170 ble heterojunctions based on two-dimensional transitional metal dichalcogenides are of great importan

171 Monolayer semiconducting transitional metal dichalcogenides have emerged as an ou

172 ry, stacking orders and spin-orbit coupling, transitional metal dichalcogenides have shown a lot of f

173 ong many-body interaction in two-dimensional transitional metal dichalcogenides provides a unique pla

174 bricate well-defined iron oxy-hydroxides and transitional metal doped iron oxy-hydroxides nanomateria

175 ching (NVRS) is a widely available effect in transitional metal oxides, colloquially known as memrist

176 on-metal signaling, where dynamic changes in transitional metal pools can modulate protein function,

177 Alloying selected layered transitional metal trichalcogenides (TMTCs) with unique

178 at exhibit NVRS, including TMDs (MX(2) , M = transitional metal, e.g., Mo, W, Re, Sn, or Pt; X = chal

179 This reversible post-transitional modification (PTM) involves the attachment

180 Suskityrannus is part of a transitional Moreno Hill (that is, Zuni) dinosaur assemb

181 een obscured by the scarcity of fossils with transitional morphologies.

182 This represents a transitional morphology between the primitive, multivalv

183 This transitional morphology had previously been hypothesized

184 large variety of movements in linguistic and transitional movement contexts.

185 tivity clearly differentiated linguistic and transitional movements, demonstrating encoding of langua

186 stinct neural activity for linguistic versus transitional movements.

187 y grouped into palaeo-biomes, we show a more transitional nature of terrestrial climate change by ind

188 fluorescence, which reflects formation of a transitional NBD1 conformation, was followed by its SUMO

189 ) mice display a progressive accumulation of transitional NK cells (tNKs) (CD27(+)CD11b(+)) with age,

190 tion of precision matrix that helps rule out transitional noises of contact-maps compared with the pr

191 that Hsp27-Ubc9 targets the SUMOylation of a transitional, non-native conformation of F508del NBD1: (

192 gesting the existence, perhaps ephemeral, of transitional objects with a layered structure whereby a

193 This study included 807 participants with transitional or diffuse LBD (mean [SD] age, 70.0 [9.9] a

194 nter database included 807 participants with transitional or diffuse LBD.

195 t can be further sub-classified into active, transitional or exhausted.

196 rends between 31 degrees and 41 degrees S; a transitional pattern in the central Patagonian Andes; an

197 lly transmitted infections (STIs) during the transitional period following foster care.

198 ints offer a unique window into an important transitional period in hominin social behavior.

199 r, the two periods were separated by a third transitional period in which beliefs about predictors' a

200 During the transitional period, the haemodynamic responses to CRE a

201 ver a woman's lifetime are largely shaped by transitional periods such as puberty, menopause and preg

202 Changes in melting temperature and transitional pH depended on both the type of modificatio

203 In contrast, during the transitional phase of infection, the level of expression

204 problems requiring full attention during the transitional phase were categorized into different group

205 fast reaction phase, a subsequent 2-to-12 h transitional phase, and a final 7-day slow reaction phas

206 Transitional phases of hypoemia and hypermia, with conse

207 ion stages, and another featuring cells with transitional phenotypes toward acinar tissue.

208 responses within LO-1, perhaps indicating a transitional point between those two organizational prin

209 Here we suggest that key transitional points in evolution extended organisms' rea

210 criptomic and pseudotime analyses identify a transitional population between CD56(bright) and CD56(di

211 ons at the top and bottom of rete ridges and transitional positions between the basal and suprabasal

212 d, additional resources should be devoted to transitional postdoctoral fellowships already offered by

213 opose that the CXCR4(hi) subset represents a transitional premonocyte population, and that this seque

214 prey availability on right whale demographic transitional probabilities and use a corresponding demog

215 Forming representations for transitional probabilities paves the way for predictions

216 al learning: The acquisition of second-order transitional probabilities was comparable with and witho

217 If deviance detection was based on transitional probabilities, then reversal deviants shoul

218 sts, including price of drug, utilities, and transitional probabilities, were included from published

219 hich they incidentally acquired second-order transitional probabilities.

220 ty with which a given sound follows another (transitional probability) allows predictions of upcoming

221 d epithelial cellular states, which is a key transitional process in kidney development.

222 g of p63(+)/CK5(+) progenitor, CK5(+)/CK8(+) transitional progenitor, and CK8(+) differentiated lumin

223 ult, adolescent; (2) adolescent development, transitional programs, transition to adult care; (3) mus

224 , respectively, and both are required in the transitional pronation step.

225 should be recast as a series of successive, transitional radiations that extended from the late Edia

226 contractile pericytes within a postarteriole transitional region differentially constrict to structur

227 within a functionally distinct postarteriole transitional region maintain the efficiency and effectiv

228 The transitional region of 200-250 kilometres in width is le

229 64 Raman spectra from cancerous, benign, and transitional regions of resected breast tissue from six

230 Immature transitional regulatory B (itBreg) cells are innate-like

231 ions and stable regimes, along with distinct transitional routes into chaos.

232 rterioles and capillaries, herein called the transitional segment (TS), which is covered by mural cel

233 rchaeological and taphonomic analysis of the transitional sequence, associated with a large regional

234 The recent fieldwork at Les Cottes (France) transitional site offers a good opportunity to document

235 We find a transitional sleep stage associated with a 7-10 Hz oscil

236 The concept of combining a structural phase transitional (SPT) material with a magnetostrictive magn

237 and extrinsic factors regulating survival of transitional stage 1 (T1) B cells are unknown.

238 eads to a loss of splenic B cells beyond the transitional stage 1.

239 inhibited maturation of pre-, immature, and transitional stage 2 B cells.

240 CD1d(hi) B10 cells, CD21(hi)CD23(hi)CD24(hi) transitional stage 2-like B cells, and CD138(+) plasma c

241 nenzymatic replication of RNA is a potential transitional stage between the prebiotic chemistry of nu

242 The transitional stage of B cell development is a formative

243 in the hepatopancreas increased in the early transitional stage until reaching a peak prior to extrud

244 6-deficient B cells between the immature and transitional stage.

245 e role of long non-coding (lnc) RNAs in this transitional stage.

246 2 (Bcl2), despite a persisting block at the transitional stage.

247 biochemical indices, and one main peak was a transitional stage.

248 dition, well-preserved fossils have revealed transitional stages in the evolution of the mammalian mi

249 and then gradually shortening throughout the transitional stages until its complete disappearance upo

250 lant roots and some may potentially occupy a transitional state between saprotrophy and biotrophy.

251 hed controls and thus appears to represent a transitional state from a normal healthy heart to HFpEF.

252 sory and premotor network and suggest that a transitional state from wakefulness to unconsciousness i

253 was observed, suggesting persistence of the transitional state in fibrosis.

254 e and more derived characters highlights its transitional state in the Pamphilioidea and complex mosa

255 irect programming path diverges into a novel transitional state rather than following the expected em

256 he cohort level suggest that it represents a transitional state to be passed through during the inter

257 Reflecting on this transitional state, we discuss how researchers will stru

258 However, the identity of transitional states and the mechanisms that drive their

259 s and cell signaling models to delineate key transitional states of differentiating cells at high res

260 ker length on the peptides' interaction with transitional states of F, solubility, membrane insertion

261 EDICTS (Epi-mark Descriptor Imaging of Cell Transitional States), to discern chromatin organizationa

262 mations interconnected within an ensemble of transitional states.

263 eolar stem cells converge on a unique Krt8 + transitional stem cell state during alveolar regeneratio

264 k functionally diverse subgroups and exhibit transitional structural features that may help explain r

265 f Bud3 and Bud4 together further weakens the transitional structure and abolishes the double ring for

266 Type 1 transitional (T1) B cells required Taok3 to rapidly resp

267 enetic reconstruction recovers Kylinxia as a transitional taxon that bridges Radiodonta and Deuteropo

268 The term "transitional tissue remodeling" describes qualitative an

269 ding naive cells, central memory (CM) cells, transitional (TM) cells, and effector memory (EM) cells.

270 witch during human B cell development at the transitional to follicular stages, which is characterize

271 s develop anergy and partial deletion at the transitional to mature B cell stage, but become Env(-) u

272 ernal progression, early-to-transitional and transitional-to-late, respectively.

273 distinct from NBCs, while unswMBCs display a transitional transcriptome.

274 rrow sense defined herein, we found that the transitional-turbulent spot inception mechanism is analo

275 en a streak is infected by a nearby existing transitional-turbulent spot.

276 ore, not the mechanisms for the inception of transitional-turbulent spots found here.

277 Although structurally quite similar to the transitional-turbulent spots, these turbulent-turbulent

278 ilitate the growth and spreading of existing transitional-turbulent spots.

279 uman transitional B cells encompass not only transitional type 1 and type 2 B cells, as previously su

280 this deficit is centered on the inability of transitional type 1 B cells to survive and to progress t

281 cells to survive and to progress toward the transitional type 2 B cell stage, whereas cells that hav

282 distinct MPhi-DC-like subsets, and two were transitional types.

283 ngiomas include meningothelial, fibrous, and transitional variants and have the characteristic imagin

284 Lumbosacral transitional vertebrae (LSTV) were observed in 13 (9%) p

285 uxes and fates of plastics in catchments and transitional waters both independently as a major transp

286 f transcriptional programs during a critical transitional window of meristem maturation, which we pro

287 confidence interval [CI], -13.1 to -7.2) in transitional women and -12.5 ml/yr (95% CI, -16.2 to -8.

288 ased by -3.8 ml/yr (95% CI, -6.3 to -2.9) in transitional women and -5.2 ml/yr (95% CI, -8.3 to -2.0)

289 Intriguingly, these transitional ZO-1 binding/release and channel-aging step

290 rate in retinitis pigmentosa (RP) and in the transitional zone (TZ) of atrophic zones (AZ), which cha

291 ific cartilage zones (superficial zone [SZ], transitional zone [TZ], and deep zone [DZ]) and regions

292 In several organ systems, the transitional zone between different types of epithelium

293 le CA2 was tentatively identified as a small transitional zone between the CA1 and CA3 fields.

294 of a matrix of wooded savanna that formed a transitional zone between the extremes of humid eastern

295 nside or at the edge of WTs, with an obvious transitional zone between WT and MEC.

296 Instead, the transitional zone for lens differentiation was shifted a

297 ur findings reveal a previously unidentified transitional zone in the epithelium of the upper gastroi

298 fines a population of pacemaker cells in the transitional zone.

299 tional columnar epithelium is present at the transitional zones of other mouse tissues (including the

300 and the central gland (combined central and transitional zones) between men with biopsy confirmed pr