ライフサイエンスコーパス: translate

1 rrors would result in amino-acid changes, if translated.

2 brafish mRNAs and found that many are indeed translated.

3 ss models, which provide a convenient way to translate across ecological currencies.

4 activated calcium (Ca(V) 1/Ca(V) 2) channels translate action potentials into Ca(2+) influx in excita

5 try is a rapidly growing field attempting to translate advances in computational neuroscience and mac

6 Learning and experience are critical for translating ambiguous sensory information from our envir

7 the present cross-sectional study, CDAT was translated and back-translated by three bilingual profes

8 ese research insights are being increasingly translated and implemented into clinical practice.

9 rface-rolling molecular machines that can be translated and rotated with extreme precision and speed,

10 bosome profiling data revealed that ORF-Y is translated and that initiation likely occurs at a CUG co

11 single-molecule tracking, we found that both translating and nontranslating RNAs exhibit dynamic cyto

12 cally ablated ten such lncRNAs, most of them translated, and found that nine are dispensable for panc

13 ne kinase (HSV1-tk) gene has previously been translated as a PET reporter gene for imaging of T-cell

14 he cytoplasmic HIV-1 RNAs are being actively translated at a given time.

15 es identified classes of mRNAs expressed and translated at different levels in WT and Upf3b-null mOSN

16 ATI mRNA is anchored by nascent peptides and translated at the inclusion sites rather than in virus f

17 rier integrity as an important checkpoint in translating autoimmunity to inflammation.

18 ming a global hydrogen taskforce in order to translate bench-top research into large-scale production

19 e definition of time- and length scales that translate between computational and laboratory units.

20 f physiological measures that can accurately translate between preclinical animal models and clinical

21 ftware uses a pipeline of code generation to translate Brian scripts into C++ code that can be used a

22 This broadened bandwidth of Ca(2+) influx is translated by cells into differential activation of NFAT

23 ectional study, CDAT was translated and back-translated by three bilingual professional translators.

24 either by clinical tools or by attempting to translate cellular mechanisms to the bedside.

25 ity could provide an efficient mechanism for translating cellular cues into a fast and accurate cohes

26 approaches are cumbersome and challenging to translate clinically.

27 exities and manifest limitations inherent in translating complex human disease to reductionist animal

28 ineurin-B-like proteins (CBLs) can sense and translate cytosolic elevation of the second messenger Ca

29 enesis, but suggests a need for caution when translating data obtained from rodent HSC to events occu

30 chnical details and precise instructions for translating digital information to DNA sequences, physic

31 formative representations of parameters that translate directly into biological function.

32 red in dry seeds and whether they are indeed translated during seed germination.

33 This change in affinity is then translated effectively into control of catalytic compete

34 osensors on the gut epithelium, are known to translate environmental cues into serotonin (5-HT) produ

35 of mitochondrial (mt-)tRNAs encoded in mtDNA translate essential subunits of the respiratory chain co

36 At the practice level (T3), translating evidence into practice remains challenging.

37 settings, providing a framework for quickly translating existing monotherapy cell line data into cli

38 n in-cell architecture of a transcribing and translating expressome at subnanometer resolution.

39 l principles of information processing or to translate findings into new therapies for neuropathology

40 Derjaguin's approximation was utilized to translate force measurements into interaction energy bet

41 Interestingly, the in vitro translated forms of the OMPs we analyzed were assembled

42 Novel therapeutics have largely failed to translate from promising pre-clinical findings into impr

43 Recently, Alternative Proteins (AltProts) translated from nonannotated Alternative Open reading fr

44 topes in two open reading frames (ORFs), one translated from the 5' cap, and the other from the encep

45 Because one moiety of the GFP is translated from the mitochondrial machinery while the ot

46 d bioinformatics, challenges associated with translating genomes into natural products, and examples

47 rofile the immune system at high resolution, translating high-throughput data into knowledge of immun

48 expression does not alter the proportion of translating HIV-1 RNA.

49 ic mRNA studies revealed that Rps28 protein, translated in cis from an mRNA bearing the RPS28B 3'UTR,

50 The X-ORF can be translated in full-length (61-amino-acid) or truncated (

51 By determining the ratio of a protein translated in mitochondria to that of a protein translat

52 nslated in mitochondria to that of a protein translated in the cytoplasm, we showed that aminoglycosi

53 d to the nuclear-encoded protein of interest translated in the cytosol, the self-reassembly of this B

54 oteins are encoded by the nuclear genome and translated in the cytosol.

55 vation, differentiation, and function, which translates in vivo to an improved ability for T cells to

56 support that GJA1-20k, an endogenous entity translated independently of Cx43, is critical for Cx43 g

57 t we find that inflammatory genes are highly translated, indicating alternative post-transcriptional

58 process of mitotic rounding is sufficient to translate interphase shape into a cortical pattern that

59 tial inhibition of PEC proliferation did not translate into a decline of albuminuria nor in a sustain

60 These changes in leaf-level photosynthesis translate into a stronger climate and CO(2) response of

61 atin binding changes in differentiated cells translate into activation of the histone H3 lysine 9 (H3

62 se progression-free survival benefit did not translate into an overall survival (OS) benefit in rando

63 iption of how physiological dopamine signals translate into changes in dopamine receptor occupation i

64 nowledge about how spinal cord abnormalities translate into clinical manifestations is incomplete.

65 tential for multisite preclinical studies to translate into clinical trials.

66 equired in the study group, but this did not translate into demonstrable gains in preservation of ren

67 tructural features of the two PA2G4 isoforms translate into different functional outcomes.

68 itarian values at a national level might not translate into equality of opportunity at an individual

69 participation in strategies with FIT do not translate into higher detection of advanced neoplasia.

70 me scale of electron transfer to Pd clusters translate into hydrogen evolution activity optima at dif

71 hronized ventricular activation, which might translate into improved clinical outcomes compared with

72 n and in ICU, but this does not consistently translate into long-term functional benefit.

73 ffect forests, it is unknown if such effects translate into long-term responses.

74 nts in the fidelity of biogeochemical models translate into lower error rates in the fisheries simula

75 ized that these understandings cannot always translate into nanoscale systems.

76 components or to stimulate GBM repair could translate into new therapies for patients with GBM-assoc

77 somal differences in centromere features can translate into non-random aneuploidy, a hallmark of canc

78 While these findings can eventually translate into personalized spray usage instructions and

79 Allergen transcripts translate into proteins with a cationic carboxy terminus

80 hat elevated rates of cesarean sections (CS) translate into reduced maternal/child perinatal morbidit

81 otentially practice-changing data that might translate into revised guideline recommendations.

82 ith depression in observational research may translate into robust targets for prevention.

83 unts of microbial biomass and necromass that translate into the observed increase in SOC.

84 in hypertension-the ways by which these cues translate into tissue maintenance, adaptation, or malada

85 d reconstruction deficiencies might directly translate into unrealistic absorbed dose distributions,

86 s of the optimum phenotype need not directly translate into variation in selection gradients, because

87 d 20 OsPLDalpha1 cDNA variants which further translated into 12 protein variants.

88 ee-pollinated than bee-isolated trees, which translated into a 20% increase in kernel yield.

89 A single nuclear gene can be translated into a dual localized protein that distribute

90 Moreover, circSfl is translated into a protein that shares the N terminus and

91 gradient in responsive tissue, which is then translated into a spatial cellular pattern.

92 In vivo, this translated into a tissue-specific vulnerability of the b

93 responding fragmentation rate constants were translated into a vibrational effective temperature T(ef

94 analytical methodology for CRE detection is translated into an all-solid-state platform, in which th

95 d platelet aggregation and SEC injury, which translated into an improved posttransplant organ functio

96 nfer therapeutic opportunities that could be translated into clinical trials.

97 tion to nanomedicine, however, has not fully translated into clinical utilization and patient benefit

98 This decoy approach has since been translated into crop species using endogenous PBS1 ortho

99 They can be translated into different functional proteoforms, and th

100 y differential "signaling fingerprints" that translated into distinct in vivo profiles.

101 These health effects have not been translated into economic costs for individuals and econo

102 is how these signaling dynamics patterns are translated into functionally appropriate gene regulation

103 These effects translated into greater chemopreventive efficacy for UVB

104 daughters born to younger mothers, and this translated into greater lifetime reproductive success.

105 We also show that thinner bark translated into higher fire-driven tree mortality in wet

106 R, and we suggest how such insights might be translated into human therapeutic strategies.

107 molecular therapies that could ultimately be translated into human trials that can correct orofacial

108 levels of estrogen receptor (ERalpha), which translated into improved growth of xenografts in the pre

109 activity against the malaria parasite, which translated into in vivo efficacy in the P. falciparum NO

110 This translated into lower overall SSI rates (5.9% vs 11.4%,

111 -brachial fat and brachial dilatation can be translated into novel clinical tools to predict successf

112 that the reported agents may potentially be translated into novel therapeutics for the treatment of

113 genic macrophage subsets can be successfully translated into novel treatment options for patients wit

114 Tumor uptake above salivary gland uptake translated into partial remission, with an odds ratio (O

115 logistic regression models, which were then translated into prediction scores.

116 emonstrate that this signature of CQI can be translated into SAM-on-gold molecular films.

117 ddition to VZHE-039 metabolic stability, has translated into significantly enhanced and sustained pha

118 r because it is not known how wakefulness is translated into sleep-active neuron depolarization when

119 ce changes resulting from this approach were translated into striking structural changes for parent a

120 s (EC(50) ranging from 5 fM to 73 nM), which translated into sub-nanomolar gammadelta T-cell-mediated

121 ol, used namely in quantum metrology, can be translated into the classical linear optical framework.

122 respective radiotracer [(18)F]PSMA-1007 was translated into the clinic and is, in the meantime, subj

123 in humans as in animals, but how a desire is translated into the decision that an action is worth tak

124 peutically, knowledge of type 3 immunity has translated into the development of IL-23- and IL-17A-blo

125 ne of the pathways in which familial risk is translated into the SCZ phenotype.

126 gradients across a tissue, which are further translated into transcriptional changes that template pa

127 The improvement in filter utilization translated into ~ 20,000 USD gross savings in filter cos

128 xpression of epithelial susceptibility genes translates into a functionally altered response to envir

129 This translates into a significant improvement in the catalyt

130 This difference in size structure translates into a twofold difference in reproductive out

131 This flexibility translates into an ensemble of ACE2 homodimer conformati

132 se at disease-vulnerable NMJs and whether it translates into an impairment of PSC-dependent repair me

133 ty complex-associated genetic susceptibility translates into autoimmune disease are not fully underst

134 stood, however, how change in perceived risk translates into change in vaccine hesitancy.

135 in how the orientation of CTCF binding sites translates into genome folding patterns.

136 for axial length on spectral-domain (SD) OCT translates into lower signal strength and scan reliabili

137 ant INSR in cultured cells, but whether this translates into meaningful metabolic benefits in vivo, w

138 as monitor patients with MS, which directly translates into significant clinical decisions.

139 d on the FAF image but not on the NIR image, translating into a sensitivity of 94.8%.

140 preclinical NP research is not consistently translating into actionable clinical trial (CT) outcomes

141 es, highlighting their importance in DCM and translating into high interpretability in diagnostic tes

142 rs: failure of preclinical research findings translating into human pain conditions, and a drop-off o

143 have been shown to confer vascular benefits translating into improved musculoskeletal, cardiopulmona

144 ted in a lower incidence of acute GVHD, thus translating into superior overall survival compared with

145 ical frequency down to a radio frequency, or translates its phase to any other optical frequency acro

146 w of these findings have yet been clinically translated, leaving ample opportunity for future transla

147 (such as centromeres) faced the challenge of translating long error-prone reads from the nucleotide a

148 3H5 is preferentially associated with poorly translated, low-stability mRNAs, the 5'-untranslated reg

149 the provision of incentives and policies to translate management options into region- and soil-speci

150 This is the first study translating metabolomic data to develop novel treatments

151 Our study lays a foundation for translating mitochondrial biology into clinical applicat

152 e tool for disease management planners which translates modeling results into actionable control advi

153 ture in the 5' untranslated region (UTR) are translated more efficiently in G2019S LRRK2 neurons.

154 Made from RNA and protein, the ribosome translates mRNA to coded protein in all living systems.

155 ated with the movement of the first ribosome-translating mRNA.

156 e cytoplasmic assemblies of proteins and non-translating mRNAs.

157 We show that this compiler can translate networks comprised of mass-action kinetics, cl

158 f experiments and in longer perspective help translate newly discovered biomarkers into readily avail

159 a lack of quantitative methods to rigorously translate observed deuteration levels into atomistic str

160 over 70 polypeptides encoded in nuclear DNA, translated on cytoplasmic ribosomes, and imported into m

161 upancy profiling, identification of actively translated open reading frames (ORFs), to the quantifica

162 With the serendipitous discoveries of translated ORFs encoded upstream and downstream of annot

163 ation product, but we also detect genes with translated ORFs on multiple transcript isoforms, includi

164 ribotricer, a method for detecting actively translating ORFs by directly leveraging the three-nucleo

165 red with other methods at detecting actively translating ORFs including short ORFs on multiple publis

166 However, the detection of translating ORFs, specifically short ORFs, from Ribo-seq

167 ons that need to be answered to successfully translate our knowledge of the intestinal microbiome and

168 opomyosin "ligand" segments were rotated and translated over potential "target" binding sites on F-ac

169 are enriched four-fold relative to the slow-translating pairs across Saccharomyces cerevisiae's prot

170 omyces cerevisiae's proteome, while the slow-translating pairs are enriched downstream of domain boun

171 The fast-translating pairs of amino acids that we identify are en

172 stem that relies on the plastid's ability to translate polycistronic mRNAs.

173 rol the physicochemical protection of carbon translate poorly to pool-based SOC models; as a result,

174 rapy, which range from lack of confidence in translating pre-clinical findings to identifying optimal

175 For example, MetaRibo-Seq identifies 2,091 translated, previously unannotated small protein familie

176 scription in yeast to our knowledge of a cis-translated protein interacting with another protein in t

177 The translated protein showed activity and protease inhibito

178 table problem of assembling centromeres from translated reads.

179 translation process, with each subsequently translated residue establishing additional native contac

180 It is difficult to translate results from animal research on addiction to a

181 Our results demonstrate the care needed when translating results from a model species to crop plants.

182 Instead, the translating ribosome actively pushes RNA polymerase out

183 ear conditioning or extinction in mice using translating ribosome affinity purification (TRAP) and RN

184 Here, we employed translating ribosome affinity purification (TRAP) and RN

185 Here, we combined translating ribosome affinity purification (TRAP) with R

186 Cell type-specific translating ribosome affinity purification and qPCR was

187 Here, we have applied a combination of translating ribosome affinity purification and ribosome

188 We applied translating ribosome affinity purification combined with

189 By using translating ribosome affinity purification coupled with

190 after miRNA inhibition were determined using translating ribosome affinity purification followed by h

191 We used translating ribosome affinity purification sequencing an

192 Translating ribosomes that slow excessively incur collis

193 thesis, charged tRNAs deliver amino acids to translating ribosomes, and are then re-charged by tRNA s

194 uently involves unmasking of target sites by translating ribosomes.

195 releasing elongating polypeptide chains from translating ribosomes.

196 ructure aimed to make a meaningful impact on translating science into the clinic.

197 oal with this approach is to help clinicians translate secondary findings into meaningful recognition

198 cal open reading frames (ORFs), thousands of translated small ORFs (containing less than 100 codons)

199 ter embryos to extend the catalog of in vivo translated small ORFs, and to reveal the translational r

200 y pathways are likely an important mechanism translating socioeconomic inequalities into mental and p

201 ta-thalassemia and could provide guidance to translate some of these approaches into viable therapies

202 highlighting key areas of attention to fully translate TENG-based biomedical sensors into clinically

203 o recognize speech, caption photographs, and translate text between languages at high levels of perfo

204 ors retrospectively developed a cycle-GAN to translate texture information from chest radiographs acq

205 Here, we show that 80S ribosomes translate the 5'-proximal short ORFs (uORFs) of piRNA pr

206 ed Annotation of Metabolism), a framework to translate the deluge of microbiome-based genomic informa

207 he ventral hippocampus is uniquely poised to translate the experience of stress into altered brain fu

208 cturally accessible form for circuit wiring, translate the input information into an arbitrary sequen

209 The ribosome translates the genetic code into proteins in all domains

210 -fluorophore mobile phone imaging may enable translating the benefits of extant laboratory-based, rea

211 ersatility of the Sec14-fold as scaffold for translating the binding of chemically distinct ligands t

212 Back-translating the clinical manifestations of human disease

213 pothesize that one module is responsible for translating the extracellular proteins required for grow

214 ation potentials and voltage-gated channels, translating the generation potentials into action potent

215 today is to shape these porous materials to translate their enhanced performance from the laboratory

216 neuroscientists and clinicians interested in translating their research to hiPSC-based studies.

217 utic promise because of the time it takes to translate them from bench to clinic.

218 do it: How do you implement the findings and translate them into policies, legislation, and practices

219 in reading the codons on messenger RNAs and translating them into proteins.

220 estions that must be addressed to clinically translate these findings in order to minimize scarring i

221 w these factors are regulated and how we can translate these findings into therapies for neurodegener

222 To help translate these methods to routine research and clinical

223 Here, we translate these observations into a diffuse interface mo

224 We sought to translate these preclinical findings to humans by examin

225 To translate these recent advancements at the global level

226 otypes 1a, 1b, 2b, and 3a, respectively, and translated these into amino acid sequences and used for

227 Then, we translated these sequences into in silico Isoform Juncti

228 How the brain receives and translates these peripheral signals or how these interac

229 When translating these data into the mobility dimension, we i

230 Translating these findings into human disease is challen

231 ther, we outline the remaining challenges in translating these findings into viable HIV prevention, t

232 drug targets is suggested, with the goal of translating these new insights about glioma metabolism i

233 However, translating these therapies to the clinic requires overc

234 able bioavailability need to be developed to translate this concept into a clinically feasible functi

235 To translate this finding, we develop endosomal pH-responsi

236 etic therapies and detail current efforts to translate this knowledge into clinical benefit for patie

237 proteins with conserved binding sites and to translate this knowledge into the design of selective in

238 To translate this prediction model into a clinical risk-str

239 etes, further optimization will be needed to translate this strategy for diagnosis of Lyme disease in

240 rtain hematological malignancies, efforts to translate this success to solid tumors have met with lim

241 The aim of this observational study is to translate this tool into arabic and test its psychometri

242 We translated this behavior into a molecular memory functio

243 sease have been well characterized, however, translating this knowledge into mechanistic insight and

244 Translating this strategy into humans will require explo

245 firing in the suprachiasmatic nucleus (SCN) translate time-of-day throughout the mammalian brain.

246 Newly translated TNKS triggers proteasomal degradation of axin

247 lated to clinical trials and it will further translate to cancer management.

248 those different binding properties directly translate to distinct biological functions: free IgE ini

249 All these properties translate to high-performance X-ray imaging with sensiti

250 in high-impact journals (p<0.05), it did not translate to higher citations (p>0.05).

251 ury reveals new therapeutic targets that may translate to improve motor recovery following nerve inju

252 that cheaper diagnostics do not necessarily translate to less costly ACF, as any savings from the te

253 ing 50% of expected calorie reductions would translate to long-term reductions.

254 However, this would translate to omnipresent persistent inflammation.

255 o explore the potential for this approach to translate to other Sub-Saharan African contexts.

256 d it is unknown how well these findings will translate to people of other ancestries and exposed to e

257 However, this skepticism does not appear to translate to peoples' health actions, as MFW appears to

258 These methods have been shown to poorly translate to studying the effects of mutations in membra

259 and an intermittently cloudy day these would translate to substantial differences in total crop carbo

260 his ability to exploit dynamic resources may translate to success in urban environments, areas charac

261 iles of brain diseases with the potential to translate to the clinic.

262 These insights might also translate to the understanding of the etiology of associ

263 This KR procedure was also translated to a continuous-flow process using a polymer-

264 This translated to a drop in median number of flights between

265 These translated to a reduction in "aortic age" by 3.9 years (

266 rage grain weight than the control, and this translated to an increase in grain yield of 11.3% in fie

267 to pay, the quality-adjusted life-year loss translated to an individual lifetime economic burden of

268 ressure autoregulation metrics have not been translated to clinical care for pediatric cardiac arrest

269 eries in resistance biology and successfully translated to clinical strategies that improve outcomes,

270 two decades, research on NIRF nanoprobes has translated to clinical trials and it will further transl

271 to exploit resources in natural environments translated to exploitation of urban resources.

272 cal research, this approach could be readily translated to human application.

273 nction, as well as how these findings can be translated to human DCs and their progenitors.

274 ising outcomes in animal models failed to be translated to human disease, our platform also incorpora

275 metabolic disorders, and how these might be translated to humans to improve metabolic health.

276 SV elimination observed in these studies, if translated to humans, would likely significantly reduce

277 can be broken down by functional groups and translated to model organisms.

278 This approach, especially if can be translated to other antiretroviral drugs, has potential

279 R trend logistic regression analyses, can be translated to other international transplant registries

280 ration approach also has the potential to be translated to other mass spectrometric analysis techniqu

281 This could be translated to other post-operative outcomes and reduce c

282 It is unclear whether these results can be translated to patients without PDR.

283 low, even large relative increases in yield translated to small absolute gains in global protein pro

284 il now advances in Lab-on-Chip have not been translated to the anticipated degree to commercialized t

285 data to assess how organismal thermal stress translated to the cellular level.

286 ed drugs, the tetracyclines could be quickly translated to the clinic.

287 ations of reduced cfmtDNA seen in lumbar CSF translated to the post-mortem ventricular CSF.

288 has been characterized, how their status is translated to transcriptional activity is not understood

289 Recently, this concept has been translated to two-dimensional photonic scenarios in conn

290 important difference, 9 points) and symptoms translated to units of the Edmonton Symptom Assessment S

291 e (QOL), and symptoms, with estimates of QOL translated to units of the Functional Assessment of Chro

292 eets and mineral dust aerosols, this cooling translates to an equilibrium climate sensitivity of 3.4

293 The extent to which increased growth translates to changes in biomass is dependent on the tur

294 nces in the nature of the peptides presented translates to differences in responding T cell repertoir

295 How this interaction translates to GP2 domain-mediated fusion of viral and en

296 To understand how lineage identity translates to neuron morphology, we mapped 18 Drosophila

297 to broadly block type 2 inflammation, which translates to protection from allergen-induced lung func

298 t therapeutic mechanism-of-action, and, back-translating to fast-track development of next-generation

299 The interviews were orally translated, transcribed, entered into Dedoose software f

300 zed by clinicians; therefore, impairment may translate with decreased access to KT.