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1 RFC is a multipass transmembrane protein.
2 in and AP-1 control the sorting of an apical transmembrane protein.
3 y inhibited by the anti-sigma factor RsiV, a transmembrane protein.
4 e formation and is mastered by p24, a type I transmembrane protein.
5 ve capacities, and cwr-2 encodes a predicted transmembrane protein.
6 to trigger budding, is synthesized as an ER transmembrane protein.
7 containing 7A (THSD7A), a podocyte-expressed transmembrane protein.
8 s amyloid protein precursor and other type I transmembrane proteins.
9 integrin ligands, lectins, and other type-1 transmembrane proteins.
10 otein Tom40 and four auxiliary alpha-helical transmembrane proteins.
11 S protein-driven entry by interferon-induced transmembrane proteins.
12 f CASP12 domains, and works just as well for transmembrane proteins.
13 r understanding clustering of other synaptic transmembrane proteins.
14 inked to retromer's role in the recycling of transmembrane proteins.
15 preference for acetylating N termini of the transmembrane proteins.
16 function of ion channels and other polytopic transmembrane proteins.
17 e further research on alloherpesvirus virion transmembrane proteins.
18 okines), extracellular matrix molecules, and transmembrane proteins.
19 improving detection of actively secreted and transmembrane proteins.
20 rse clients, from tail-anchored to polytopic transmembrane proteins.
21 internal vesicular transport of cortex-bound transmembrane proteins.
22 (Cn symmetry) found in most homo-oligomeric transmembrane proteins.
23 t themselves from potentially toxic aberrant transmembrane proteins.
28 +)/Ca(2+)/Mn(2+) exchanger known as TMEM165 (transmembrane protein 165) participates in normal milk p
29 n the gene encoding the human Golgi TMEM165 (transmembrane protein 165), belonging to UPF0016 (unchar
31 -) channel, anoctamin 1 (Ano1, also known as transmembrane protein 16A) contributes to intestinal pac
33 induced phosphatidylserine exposure through transmembrane protein 16F, a calcium-dependent phospholi
34 ease from macrophages and monocytes, whereas transmembrane protein 173-dependent TANK-binding kinase
41 we determined that fibronectin leucine-rich transmembrane protein 2 (FLRT2), a repulsive ligand of t
43 fied the cell-surface hyaluronidase (HAase), Transmembrane Protein 2 (TMEM2), as a potent modulator o
45 uolar protein sorting 37 homolog A (VPS37A), transmembrane protein 251 (TMEM251), amyotrophic lateral
46 the antiviral restriction factor IFN-induced transmembrane protein 3 (IFITM3) are associated with sus
49 The antiviral restriction factor IFN-induced transmembrane protein 3 (IFITM3) inhibits cell entry of
51 egulation and function of interferon-induced transmembrane protein 3 (IFITM3), an antiviral immune ef
55 , and TMEM64 (VTT) domain-containing protein transmembrane protein 41B (TMEM41B) for infection by SAR
59 re, coexpression of the viral reticulon-like transmembrane protein A17 and the capsid-like scaffold p
61 data, revealed an unanticipated strategy for transmembrane protein acylation with catalysis occurring
62 t droplets can harbor functional soluble and transmembrane proteins, allowing for the colocalization
63 ionic proteins, can alter the disposition of transmembrane proteins and causes the local accumulation
64 diated ER translocation to include multipass transmembrane proteins and suggest that TRPC6 N-glycosyl
65 ncrease stability and ion conductance of the transmembrane protein, and lysosomal localization was no
67 eases are involved in ectodomain cleavage of transmembrane proteins, and ADAM17 is known to cleave Ne
69 viral restriction factor interferon-induced transmembrane protein are markedly higher in the prefron
72 at almost the entire populations of all four transmembrane proteins are immobilized by either the inc
75 ntified TMEM79/MATTRIN, an orphan multi-span transmembrane protein, as a specific inhibitor of Wnt/FZ
76 spectrometry to identify vezatin, a two-pass transmembrane protein, as an acetylcholine receptor (ACh
77 that most of these genes encode single-pass transmembrane proteins, as seen in another resistance re
80 iruses translate their genomes as multi-pass transmembrane proteins at the endoplasmic reticulum (ER)
81 t determination of extracellular segments of transmembrane proteins based on the identification of su
82 tif alone is insufficient to induce RAT of a transmembrane protein because TM4SF4, a relative of TM4S
83 keleton via its N-terminal half and with the transmembrane protein beta-dystroglycan via its C-termin
85 ighlight how flaviviruses hijack the EMC for transmembrane protein biogenesis to achieve optimal expr
87 e presence of IgE autoantibodies against the transmembrane protein BP antigen 2 (BP180, type XVII col
88 R as the Vgamma9Vdelta2 T cell Ag-presenting transmembrane protein butyrophilin 3A1, providing inform
89 , and RAT leads to an inverted topology of a transmembrane protein by altering the direction of its t
90 a method to interrogate the organization of transmembrane proteins by measuring their mobilities wit
91 hese properties enable regulation of certain transmembrane proteins by regulated intramembrane proteo
93 reviously reported that ceramide regulates a transmembrane protein called TM4SF20 (transmembrane 4 L
96 nct S-acylated domains in the same polytopic transmembrane protein can be regulated by different acyl
99 ermeability via modulating expression of the transmembrane protein claudin-8, we used cultured mouse
101 endocytosis (CME) is key to maintaining the transmembrane protein composition of cells' limiting mem
102 ction in insulin SG number, changes in their transmembrane protein composition, and defects in granul
103 ow that most short homopolymeric polyleucine transmembrane proteins containing single amino acid subs
108 s TRAP, Cathepsin K, dendritic cell-specific transmembrane protein (DCSTAMP), nuclear factor of activ
110 l that peptidisc peptides can arrange around transmembrane proteins differently, thus revealing the s
113 ntegrin and metalloprotease 10 (ADAM10) is a transmembrane protein essential for embryonic developmen
114 purified components FtsZ, FtsA and truncated transmembrane proteins essential for cell division.
115 revealed that the vast majority of all four transmembrane proteins exhibit very restricted movement
118 or expressed on myeloid cells 2 (TREM2) is a transmembrane protein expressed on microglia within the
123 onsisting of ER targeted proteins, including transmembrane proteins, glycoproteins, and proteins with
127 ree recent studies find that the single-pass transmembrane protein HAP2 mediates gamete fusion and is
129 ting the brain for NCLs caused by defects in transmembrane proteins has been more challenging and onl
130 Bacteriorhodopsin (bR), a representative transmembrane protein, has demonstrated exceptional opto
132 ent revolutions in the structural biology of transmembrane proteins have, for the first time, yielded
134 in type III domain containing 5 (Fndc5) is a transmembrane protein highly expressed in the skeletal m
136 hically solved structures of homo-oligomeric transmembrane proteins (HoTPs) and find that ~97% are Cn
143 sts or mouse cells, we show that IFN-induced transmembrane proteins (IFITMs), a family of restriction
144 tiviral function is the interferon-inducible transmembrane proteins (IFITMs), of which IFITM3 has bee
145 cell-intrinsic factors (interferon-inducible transmembrane proteins, IFITMs), on the pH regulation in
146 gs were: (i) the FL strain encodes 16 virion transmembrane proteins; (ii) eight of these proteins are
147 Fatty acid transport protein 4 (FATP4), a transmembrane protein in the endoplasmic reticulum (ER),
148 mice deficient in NRROS, a myeloid-expressed transmembrane protein in the endoplasmic reticulum, deve
149 ne fusion is triggered by synaptotagmin-1, a transmembrane protein in the vesicle membrane (VM), but
150 HIV-1 particles incorporate various host transmembrane proteins in addition to viral Env glycopro
151 heterodimers in metazoans and single subunit transmembrane proteins in apicomplexans such as TRAP in
152 scopy for the analysis of oligomerization of transmembrane proteins in cell-derived lipid membranes.
154 e outer membrane leaflet, interacts with the transmembrane protein integrin beta1 and activates focal
157 e that ODZ1 (also known as TENM1), a type II transmembrane protein involved in fetal brain developmen
158 egrin and Metalloproteinase-15 (ADAM15) is a transmembrane protein involved in protein ectodomain she
161 e identification of transmembrane helices in transmembrane proteins is crucial, not only to understan
164 /H(+) exchanger type I (chNHE1), a multispan transmembrane protein, is a cellular receptor of the sub
165 port here that TMEM203, a conserved putative transmembrane protein, is an intracellular regulator of
167 riguingly, there was also association with a transmembrane protein kinase that may function as a rece
168 dentified the leucine-rich repeat-containing transmembrane protein known as Fish-lips (Fili) as a nov
171 vel research suggests that disruption to the transmembrane protein linkage between the cytoskeleton a
173 ur model consists of a molecular paddling by transmembrane proteins linked to and advected by the act
175 We discovered that Shisa7, a single-passing transmembrane protein, localizes at GABAergic inhibitory
176 we term "megacyte," is defined by a specific transmembrane protein marker (TM7318) and high expressio
179 lic end-products is facilitated by polytopic transmembrane proteins mediating secondary active or pas
180 VE-cadherin, occludin and interferon-induced transmembrane protein mRNAs compared to both "low inflam
182 affic, including the poorly understood small transmembrane proteins neural-specific gene 1 and 2 (Nsg
183 e-wide haploid genetic screen identified the transmembrane protein neuropilin 2 (NRP2) and tetraspani
184 hy with subcortical cysts 1 (Mlc1), an eight-transmembrane protein normally expressed in perivascular
185 ve triple response 1 (CTR1); an ER-localized transmembrane protein of unknown biochemical activity, c
186 biquitin ligase WWP2 and a tumor-suppressing transmembrane protein of unknown biochemical function, T
189 4) domain of Sun proteins [5-7], a family of transmembrane proteins of the inner nuclear membrane (IN
192 effective means for studying the effects of transmembrane proteins on lipid distribution in both sym
194 alpha) expressed on myeloid cells to CD47, a transmembrane protein overexpressed on cancer cells, act
196 is a common solubilizing agent used to study transmembrane proteins/peptides in biological and synthe
198 een the helical membrane-spanning domains of transmembrane proteins play central roles in the proper
200 ch on alloherpesvirus VTPs.IMPORTANCE Virion transmembrane proteins play key roles in the biology of
201 igh throughput RNA sequencing identified the transmembrane protein Pmepa1 as a differentially express
203 kidney disease (ADPKD), encode the multipass transmembrane proteins polycystin-1 (PC1) and polycystin
204 Mutations in PKD1 and PKD2, which encode the transmembrane proteins polycystin-1 and polycystin-2, re
205 , the de novo design of stable, well-defined transmembrane protein pores that are capable of conducti
206 Chloroplasts integrate nearly all thylakoid transmembrane proteins posttranslationally, but mechanis
208 The translocator protein (TSPO), an 18-kDa transmembrane protein primarily found in the outer mitoc
209 domains to interact with Rab7-GTP and the ER transmembrane protein Protrudin and together these compo
210 ms, such as the excluded volume of polytopic transmembrane proteins, proximity FRET, and rotational d
214 to the classical pathway of secretion, some transmembrane proteins reach the plasma membrane through
216 ue to mutations in the NPC1 gene, encoding a transmembrane protein related to the Sonic hedgehog (Shh
217 t to date, there are no solved structures of transmembrane proteins representing these attractive the
220 aperone that improves trafficking of several transmembrane proteins, restored Abeta-induced impaired
226 r-like receptor Patched1 regulates the seven-transmembrane protein Smoothened remains mysterious, par
227 the ubiquitin hydrolase that deubiquitinates transmembrane proteins sorted as cargoes into ILVs.
229 termini of NPHP4 and NPHP5 interact with the transmembrane protein SSTR3 and thus spatially map to th
230 localize to distal cell ends, the four-pass transmembrane protein Strabismus and the cytoplasmic pro
232 canonical Hh signaling through smoothened, a transmembrane protein targeted by small-molecule Hh inhi
233 t CUB domain-containing protein 1 (CDCP1), a transmembrane protein that acts as a substrate for SRC f
235 ession of the mRNA encoding ferroportin 1, a transmembrane protein that cooperates with CP and HEPH t
236 how that NRG3, like CRD-NRG1, is a dual-pass transmembrane protein that harbors a second transmembran
238 The only known ligand, 4-1BBL, is a trimeric transmembrane protein that has no costimulatory activity
239 The interleukin 3 receptor (CD123) is a transmembrane protein that is absent or hardly expressed
241 how that PINCH-1 interacts with myoferlin, a transmembrane protein that is critical for cancer progre
242 ceptor is an evolutionarily highly conserved transmembrane protein that is essential to a wide spectr
243 gered by mutations in NPC1, a multi-spanning transmembrane protein that is trafficked through the exo
247 The regulated trafficking of Sanpodo, a transmembrane protein that potentiates receptor activity
249 as TMEM97, an endoplasmic reticulum-resident transmembrane protein that regulates the sterol transpor
250 rt that Selenoprotein N (SEPN1) is a type II transmembrane protein that senses ER calcium fluctuation
251 and stabilizes Smoothened (Smo), the 7-pass transmembrane protein that transduces the Hh signal.
252 AtUPS5 (Arabidopsis UREIDE PERMEASE 5) is a transmembrane protein that transports allantoin with hig
254 contact sites composed of clustered connexin transmembrane proteins that act in dual capacities as ch
256 ry of a family of endoplasmic reticulum (ER) transmembrane proteins that associate with and modulate
257 uclear membrane is functionalized by diverse transmembrane proteins that associate with nuclear lamin
259 ture virions, were severely deficient in the transmembrane proteins that comprise the entry fusion co
260 Voltage-gated sodium channels (VGSC) are transmembrane proteins that generate an action potential
262 ensions in studying GABA(A)Rs due to several transmembrane proteins that interact with GABA(A)Rs and
265 ted sodium (Na(V)) channels are pore-forming transmembrane proteins that play essential roles in exci
266 Tetraspanins are a unique family of 4-pass transmembrane proteins that play important roles in a va
268 findings identify the PCDHGs as pro-survival transmembrane proteins that select inhibitory interneuro
269 enes that encode Polycystin 1 and 2 (PC1/2), transmembrane proteins that translocate to the cilium.
271 naling network largely initiated by three ER transmembrane proteins, the UPR constantly surveils prot
272 gy-related gene 9 (Atg9) encodes a multipass transmembrane protein thought to act as a membrane carri
276 nation state of embedded charged residues in transmembrane proteins (TMPs) can control the onset of p
277 includes the APMS, the phospholipid bilayer, transmembrane proteins (TMPs), and integral monotopic pr
278 tropic system requiring only a retinal-bound transmembrane protein to convert photons of light to an
280 ct cargo-selecting module for a large set of transmembrane proteins transiting the endosome, in addit
281 Starting with an unbiased screen of ~ 1,500 transmembrane proteins using the purified GluN1-NTD prot
282 ion translocation by Ca(2+)-regulated TMEM16 transmembrane proteins utilizes a membrane-exposed hydro
283 -binding Proteins (SMP) domain-containing ER transmembrane protein, utilizes distinct domains to inte
284 Here, we found that the V. dahliae tetraspan transmembrane protein VdSho1, a homolog of the Saccharom
289 Cytochrome bo (3) ubiquinol oxidase is a transmembrane protein, which oxidizes ubiquinone and red
290 The TMC genes encode a set of homologous transmembrane proteins whose functions are not well unde
292 und that OIG-8, a previously uncharacterized transmembrane protein with a single immunoglobulin (Ig)
293 In the present study, we found that USH2A, a transmembrane protein with a very large extracellular do
295 n as integrin-associated protein (IAP), is a transmembrane protein with multiple biological functions
296 ntributions when designing drugs that target transmembrane proteins with improved efficacy and safety
299 iors.SIGNIFICANCE STATEMENT Ion channels are transmembrane proteins with selective permeability to sp
300 re we report that modification of several ER transmembrane proteins with the photosensitive degron (p