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1  betaine is as an osmolyte and methyl donor (transmethylation).
2 roach to achieve transalkylation rather than transmethylation.
3 ilic substitution (SN2) transition state for transmethylation.
4 nly metahydroxyl groups to be positioned for transmethylation.
5 he intermediates of phosphatidylethanolamine transmethylation.
6 t this mutation affects the chemical step of transmethylation.
7 n, as a key direct target of METTL3-mediated transmethylation.
8 Despite the presence of motifs essential for transmethylation activity, catalytic activity of DNMT2 h
9 ansferase, thereby inhibiting the respective transmethylation activity.
10                                              Transmethylation affects several cellular events, includ
11  their common S-adenosylmethionine-dependent transmethylation and has implications for human MTHFD1-a
12 e N-methyltransferase regulates flux through transmethylation and hence the S-adenosylmethionine/S-ad
13     We aimed to measure methionine flux, its transmethylation and its transsulfuration, and homocyste
14 egulators of biochemical reactions linked to transmethylation and polyamine metabolism.
15 is is associated with dysregulation in brain transmethylation and polyamine pathways.
16 is study, we observed broad dysregulation of transmethylation and polyamine synthesis/catabolism, inc
17                            We find that both transmethylation and propylamine transfer fluxes amount
18 centrations of metabolites in the methionine transmethylation and transsulfuration pathways in childr
19 thylation or methionine transsulfuration and transmethylation between the groups at clinical phase 1.
20 o catalyze S-adenosyl-L-methionine-dependent transmethylation by UPM1 in a multistep process involvin
21        It suffers two major metabolic fates: transmethylation catalyzed by methionine synthase or bet
22                                  Some of the transmethylation changes are inherited and some affect g
23  analyzing the transcripts and activities of transmethylation enzymes in the livers of the same micro
24 raised about labile methyl balance and total transmethylation fluxes, and further discussion has been
25 onstrating the necessity of pcMTase-mediated transmethylation for steroid induced Na(+) reabsorption.
26                               MtvA catalyzes transmethylation from MtvC to tetrahydrofolate, forming
27 r, despite considerable effort in the 1980s, transmethylation has never been established as a compone
28  neutrophils and strongly suggest a role for transmethylation in chemotaxis of eukaryotic cells.
29 hionine and its rate of transsulfuration and transmethylation in healthy women with advancing gestati
30 definitive measurements of the rate of total transmethylation in humans of both sexes on various diet
31  pathways for S-adenosylmethionine-dependent transmethylation in mammals are the syntheses of creatin
32 nd assuming insignificant transamination and transmethylation in this tissue.
33                    Here, we demonstrate that transmethylation inhibition by a novel reversible S-aden
34                           Treatment with the transmethylation inhibitor averted, and even ameliorated
35 indicate that S-adenosylmethionine-dependent transmethylation is inhibited in mthfd1-1.
36        These results suggest that a critical transmethylation is necessary for aldosterone-induction
37                        The data suggest that transmethylation is required for CD4 T cell activation,
38     The significant improvements observed in transmethylation metabolites and glutathione redox statu
39 ify this methodology by means of a one-stage transmethylation method and a fast GC run, evaluating th
40 enzymes important for N6-methyladenosine RNA transmethylation (METTL4, YWHAB, and YTHDF3), which regu
41 ial diet for 18 weeks and then switched to a transmethylation micronutrient-supplemented (MS) or -res
42      DNA methylation depends on both dietary transmethylation micronutrients and ERK-regulated DNA me
43 zes the S-adenosylmethionine (SAM)-dependent transmethylation of 6-TPs and shares 45% similarity (33%
44 ent O-methyltransferases (OMTs) catalyze the transmethylation of a variety of phenolics in bacteria,
45 e deregulated MTHFR cells undergo continuous transmethylation of homocysteine by methyltetrahydrofola
46 e in the methionine cycle that catalyzes the transmethylation of homocysteine to methionine in a coba
47 tion early in gestation and a higher rate of transmethylation of methionine in late gestation.
48                                              Transmethylation of methionine was significantly higher
49       Homocysteine, which is produced by the transmethylation of methionine, can be either remethylat
50 suring the catalytic properties of enzymatic transmethylation of phenolics.
51                        However, the role the transmethylation of phosphatidylethanolamine plays in th
52 hilic nature of S-adenosyl-l-methionine, the transmethylation of the demethylated precursor of vitami
53 wer rates of methionine transsulfuration and transmethylation or homocysteine remethylation.
54 tiation and nephrogenesis, whereas enhancing transmethylation or increasing METTL3 activity facilitat
55                                     Reducing transmethylation or inhibiting METTL3 blocks NPC differe
56  that methionine transamination, and not the transmethylation or transsulfuration pathways, contribut
57 men (P < 0.005) and a tendency toward higher transmethylation (P < 0.10).
58 xogenous adenosine reduces activation of the transmethylation pathway and attenuates the endothelial
59 rther show that the up-regulation of the SAM transmethylation pathway and the efficiency of the immun
60 lux of homocysteine through the MS-dependent transmethylation pathway in HepG2 and 293 cells, respect
61                   Here, we show that the SAM transmethylation pathway is up-regulated during immune c
62 dings reveal a modifiable methionine-SAM-RNA transmethylation pathway that can be targeted to enhance
63 ine in endothelial cells, and activating the transmethylation pathway through increasing the associat
64 of DNA via biochemical interference with the transmethylation pathway.
65 hylation potential and increased flux in the transmethylation pathways, increased demand on antioxida
66 rwardly and quickly way by using a one-stage transmethylation procedure followed by a fast GC-FID run
67  S-adenosyl-L-homocysteine (AdoHcy/SAH), the transmethylation product of AdoMet-dependent methyltrans
68 nd the protein catalyzed a methyl iodide:CoM transmethylation reaction at a rate of 2.3 micromol/min/
69                               It catalyzes a transmethylation reaction in which a methyl group is tra
70  iron-sulfur protein that is involved in the transmethylation reaction.
71 enosylmethionine (AdoMet), a key molecule in transmethylation reactions and polyamine biosynthesis.
72 sylmethionine (AdoMet), a metabolite used in transmethylation reactions and polyamine synthesis.
73 onine and ATP, is the major methyl donor for transmethylation reactions and propylamino donor for the
74                       These novel effects on transmethylation reactions may be implicated in the path
75 mpairment because of its requirement for two transmethylation reactions that can both be inhibited by
76                      For model systems, such transmethylation reactions were confirmed by LC-MS, nucl
77 r SAH), a common product of AdoMet-dependent transmethylation reactions, is first hydrolyzed by recom
78 ble for purine and thymidylate synthesis and transmethylation reactions, plays a critical role in emb
79 it is needed to metabolize the by-product of transmethylation reactions, S-adenosylhomocysteine (AdoH
80             As a methyl donor for biological transmethylation reactions, S-adenosylmethionine (SAMe)
81 hibition of purine and pyrimidine synthesis, transmethylation reactions, translocation of nuclear fac
82 e TGS by nonspecifically inhibiting cellular transmethylation reactions.
83 eptor molecule, is a potent inhibitor of all transmethylation reactions.
84  activities of hepatic enzymes that regulate transmethylation reactions.
85 olyamine metabolism and in the regulation of transmethylation reactions.
86 imited role to support SAM-dependent protein transmethylation reactions.
87 rs to be established, but several aspects of transmethylation remain uncertain: definitive measuremen
88 that S-adenosylmethionine (SAM) and cellular transmethylation status are crucial determinants of the
89  Here we provide the first evidence that the transmethylation step of the SDPM pathway occurs in the
90  studies provide the first evidence that the transmethylation step of the SDPM pathway of P. falcipar
91                While distal from the site of transmethylation, the propanoid tail substituent governs
92  PET) and indicated that the contribution of transmethylation to total hind limb methionine utilizati
93 centrations by altering its flux through the transmethylation, transsulfuration, and transamination m
94 acid, would improve plasma concentrations of transmethylation/transsulfuration metabolites and glutat
95                           Metabolites in the transmethylation/transsulfuration pathway were measured
96 etabolism is homocysteine, which can undergo transmethylation via methionine synthase (MS) or transsu
97 ing the first trimester, whereas the rate of transmethylation was higher during the third trimester.