ライフサイエンスコーパス: transmigrate

1 by regulating the numbers of leukocytes that transmigrate.

2 with the endothelium, but the majority still transmigrated.

3 ile 1.6 +/- 0.3% of the progenitor cells had transmigrated.

4 rs with endothelial ICAM-1 as the neutrophil transmigrates.

5 crovascular endothelium before arresting and transmigrating.

6 on leukocyte migration and their ability to transmigrate across an activated endothelial monolayer.

7 ector memory (EM) CD4(+) T cells can rapidly transmigrate across an endothelial cell (EC) monolayer i

8 or cell extravasation where cancer cells can transmigrate across an endothelial monolayer into a hydr

9 scoidal particles with diameters <20 nm that transmigrate across an in vitro blood-brain barrier mode

10 Moreover, these nanoplexes were shown to transmigrate across an in vitro model of the blood-brain

11 abilities to attach onto the vessel wall and transmigrate across endothelia.

12 Human effector memory CD4 T cells may transmigrate across endothelial cell (EC) monolayers eit

13 led that human platelets did not efficiently transmigrate across human epithelial cell monolayers.

14 s of blood-derived monocytes were allowed to transmigrate across human HSECs into a collagen matrix.

15 ributes to the diminished ability of PMNL to transmigrate across model intestinal epithelia.

16 Human neutrophils were induced to transmigrate across monolayers of human lung epithelial

17 proteins ZO-1 and occludin and were able to transmigrate across polarized airway epithelial monolaye

18 T(reg) cells that transmigrate across single-cell layers of endothelial ce

19 is predominantly rounded, and cells reverse transmigrate across sinusoidal endothelium in a largely

20 NS) by HIV-1 infected mononuclear cells that transmigrate across the blood brain barrier (BBB).

21 Upon inflammation, leukocytes rapidly transmigrate across the endothelium to enter the inflame

22 To infiltrate the CNS, monocytes transmigrate across the selectively permeable blood-brai

23 compromised in their ability to bind to and transmigrate across the squamous epithelium compared to

24 must destabilize the endothelial barrier and transmigrate across the vessel wall.

25 The same cells rapidly (within 15 min) transmigrate across TNF-treated EC monolayers overlaid w

26 at KDR-expressing lymphocytes preferentially transmigrate across TNFalpha-activated ECs.

27 lating human peripheral blood CD4 T cells to transmigrate across tumor necrosis factor (TNF)-treated

28 Monocytes and lymphocytes transmigrated across cytokine-treated cocultures in grea

29 whereas 11.7% +/- 3.3% of proliferating CFCs transmigrated across endothelium, only 1.3% +/- 0.3% of

30 ophages and, to a lesser extent, lymphocytes transmigrated across fetal intestinal epithelia.

31 V-infected macrophages, but not lymphocytes, transmigrated across fetal oral epithelia.

32 rmore, CAR and DeltaCAR Tregs preferentially transmigrated across HLA-A2-expressing endothelial cell

33 Only 40% of firmly adherent monocytes transmigrated across the endothelial monolayer with sign

34 Together, these data show that EBV transmigrates across oral epithelial cells by (i) apical

35 rough narrow capillaries, and actively, when transmigrating across endothelial cells or squeezing thr

36 9 blocked over 80% of human neutrophils from transmigrating across HUVEC monolayers in an in vitro mo

37 f intestinal epithelial cells induces PMN to transmigrate, an in vitro model consisting of cultured h

38 Gal) is co-administered with ET, neutrophils transmigrate and attack parenchymal cells.

39 In these livers, neutrophils did not transmigrate and liver injury was prevented (necrosis: <

40 te, as evidenced by an increased capacity to transmigrate and produce proinflammatory cytokines on st

41 findings were 1) administered MNC hUCB cells transmigrated and diffused into the embryos (E12.5); 2)

42 vant for the injury accumulate in sinusoids, transmigrate, and adhere to hepatocytes.

43 SRF-deficient macrophages fail to spread, transmigrate, and phagocytose bacteria, and SRF-deficien

44 untreated adherent neutrophils rolled, a few transmigrated, and the number that attached decreased wi

45 cells derived from CD16(+) monocytes reverse transmigrated, and their presence was associated with mi

46 A minority of CD16(-) monocytes reverse transmigrated, and these cells stimulated T cell prolife

47 gamma, EGFP(high) cells rolled, adhered, and transmigrated at a rolling velocity slightly higher (11

48 o revascularization and subsequently reverse-transmigrate back to the vasculature, actively leaving s

49 s used by macrophages versus cancer cells to transmigrate basement membrane barriers harboring physio

50 phages deploy actomyosin-generated forces to transmigrate basement membrane pores, thereby providing

51 To transmigrate basement membrane, cells must coordinate di

52 rythroid progenitors and pre-B cells neither transmigrate beneath the stroma nor expand-properly in v

53 Transmigrating canine after consultation with the surgeo

54 , which allowed precise visualization of the transmigrating canine as well as ruled out resorption of

55 Transmigrated CD34 cells expressed a higher level of CD3

56 rdingly, the total plating efficiency of the transmigrated CD34+ cells for lineage-committed progenit

57 (LFA)-1 was found, L-selectin expression on transmigrated CD34+ cells was lost, suggesting that shed

58 aternal and embryonic parts of placentas; 4) transmigrated cells corrected Naglu enzyme activity in a

59 d diffused into the embryos (E12.5); 2) some transmigrated cells expressed CD34 and CD117 antigens; 3

60 In particular, the plating efficiency of transmigrated cells for erythroid progenitors was 27-fol

61 r and bone marrow endothelium and that these transmigrated cells preserve their capacity to lyse leuk

62 The number of transmigrated cells was reduced by blocking antibodies t

63 tumor cells was rare, and it seemed that the transmigrated cells were cleared quickly by the lung, le

64 cells expressed CD34 and CD117 antigens; 3) transmigrated cells were found in both the maternal and

65 novel approach for morphological analysis of transmigrating cells, we show that ECs exhibit a polariz

66 ormation, even without intervention from the transmigrating cells.

67 In consequence, transmigrated double-knockout macrophages were seen to a

68 o determine the pathway by which neutrophils transmigrated endothelium, we prepared 27 sets of serial

69 the distal portion locally, and thereby the transmigrated epiblast cells emerge as the DVE cells.

70 and leukotrienes that activate leukocytes to transmigrate from postcapillary venules.

71 How HSPCs transmigrate from the vasculature to the niches is uncle

72 sure, suggesting that these cells could have transmigrated from inflamed tissue, such as the skin.

73 into PLNs in mice, although LDeltaP T cells transmigrated HEVs more slowly.

74 eased capacity of HIV-infected leukocytes to transmigrate in response to CCL2 correlated with their i

75 ction of leukocytes affects their ability to transmigrate in response to chemokines and to alter BBB

76 at effector memory CD4+ T cells will rapidly transmigrate in response to the inflammatory chemokine I

77 IV-infected cells added to our model did not transmigrate in the absence of CCL2, nor did this condit

78 ed lateral motility on endothelial cells and transmigrate in-efficiently.

79 Neutrophils transmigrated in higher number and further in geltrex mi

80 tory or natural strain T. gondii tachyzoites transmigrated in larger numbers across simulated human r

81 to use very late Ag-4/VCAM-1 interactions to transmigrate into liver parenchyma in vivo.

82 ation and endothelial dysfunction, monocytes transmigrate into the aortic intimal areas, and differen

83 Recruited granulocytes transmigrate into the cocoon where they release extracel

84 lammation polymorphonuclear leukocytes (PMN) transmigrate into the lumen and release 5'-AMP.

85 n injury mobilizes circulating leukocytes to transmigrate into the perivascular space and brain paren

86 In the initial stages of disease, monocytes transmigrate into the subendothelial space and different

87 ukocytes to leave the circulatory system and transmigrate into tissue.

88 itions, when leukocytes need free passage to transmigrate into tissues, TNF-alpha decreases platelet

89 otic tissue, a majority of MP that initially transmigrated into the amnion later exited by migrating

90 Neutrophils transmigrated into the aspirate fluid from children with

91 . influenzae and S. aureus compared to those transmigrated into the aspirate fluid from children with

92 Engrafted circulating monocytes transmigrated into the perisinusoidal space and acquired

93 that radiolabeled leukocytes from adult rats transmigrated into the peritoneum of other adult rats 5

94 pha, joined by protein kinase C (PKC) alpha, transmigrates into the nucleus.

95 crovascular endothelium before arresting and transmigrating into inflamed tissues.

96 cells would reduce the number of leukocytes transmigrating into the allograft, thereby attenuating t

97 revented hematopoietic progenitor cells from transmigrating into the developing liver, and Gata4-muta

98 ellular migration, LBRC membrane invests the transmigrating leukocyte.

99 This membrane surrounds the transmigrating leukocyte.

100 creased the number of rolling, adhering, and transmigrated leukocytes (P<0.01 vs. control mesenteries

101 chemokines by pancreatic acinar cells and/or transmigrated leukocytes.

102 creased the number of rolling, adhering, and transmigrated leukocytes.

103 pedesis can be mechanically regulated by the transmigrating leukocytes and by proinflammatory signals

104 microvilli-like projections that surrounded transmigrating leukocytes and drove redistribution of th

105 Decoupling the stresses exerted by the transmigrating leukocytes and the VECs reveals that the

106 e to micrometer-scale disruptions induced by transmigrating leukocytes, endothelial cells generate un

107 Light microscopy and ploidy determination of transmigrated MKs demonstrated predominance of polyploid

108 a pronounced anti-inflammatory effect on the transmigrated monocytes by downregulating, for example,

109 ctin shedding directly regulates polarity in transmigrated monocytes, which affirms an active role fo

110 icantly increased pseudopodial extensions in transmigrating monocytes, which potentiated invasive beh

111 ed from the blood or bone marrow of EAE mice transmigrate more efficiently than do neutrophils of nai

112 Furthermore, brain-derived viruses did not transmigrate more efficiently than lymphoid-derived viru

113 We found that Ly6G(+) cells transmigrated more efficiently across lal(-/-) ECs than

114 ver, once extravasated, CD18(-/-) leukocytes transmigrated more rapidly than their WT counterparts.

115 blockade of histone-DNA complexes attenuated transmigrated neutrophil-induced neuronal death, whereas

116 Transmigrated neutrophils also released decondensed DNA

117 nt role for Gal-9, with increased numbers of transmigrated neutrophils following Gal-9 administration

118 Neurotoxicity was induced by the addition of transmigrated neutrophils or conditioned medium, taken f

119 key neutrophil proteases in the presence of transmigrated neutrophils rescued neuronal viability.

120 Transmigrated neutrophils stained positively for laminin

121 tive alpha6beta1 integrins on the surface of transmigrated neutrophils was blunted in mice deficient

122 Flow cytometric analysis of transmigrated neutrophils with mAb to L-selectin reveale

123 eutrophils or conditioned medium, taken from transmigrated neutrophils, to neurons and was partially

124 AM-1 expression on intravascular and locally transmigrated neutrophils.

125 ells, and we provide evidence for a role for transmigrating neutrophils and other immune cells in the

126 rmore, evidence was obtained indicating that transmigrating neutrophils carry laminins on their cell

127 permissive nature, LERs acted as "gates" for transmigrating neutrophils in all inflammatory reactions

128 nulocytes with similar phenotypes to reverse transmigrating neutrophils observed in the mice post-UV

129 In summary, transmigrating neutrophils secrete localized elastase th

130 lization that define the preferred route for transmigrating neutrophils, we have identified a plausib

131 eping this opening tightly closed around the transmigrating neutrophils.

132 zed transwells, compatible with the study of transmigrating neutrophils.

133 hat are preferentially used and remodeled by transmigrating neutrophils.

134 es attach to endothelial adhesion molecules, transmigrate out of circulation, and localize within tis

135 rane protein occludin in regions of actively transmigrating PMN and in quiescent areas in the biopsy

136 ution of cortactin in the region surrounding transmigrating PMN.

137 in epithelial cells immediately adjacent to transmigrating PMN.

138 In this study, we assessed whether transmigrating PMNs can regulate barrier function throug

139 ences disease outcomes, we hypothesized that transmigrating PMNs influence the transcriptional profil

140 Transmigrating PMNs rapidly depleted microenvironmental

141 nism activating the host-defense function of transmigrating PMNs.

142 issociation, which is also restricted to the transmigrating pseudopod.

143 Moreover, the shedding was localized to transmigrating pseudopods within the subendothelial spac

144 e regulator of shedding) specifically within transmigrating pseudopods.

145 , and T-cell stimulatory capacity of reverse transmigrating (RT) and subendothelial (SE) monocytes we

146 ls through the endothelium and homing of the transmigrated T cells into the pancreatic islets.

147 The total number of adherent plus transmigrated T cells was also similar in both direction

148 fferences in the morphological appearance of transmigrating T cells as well as in the molecules that

149 class II MHC molecules, it is probable that transmigrating T cells encounter cognate antigen on endo

150 By imaging a RhoA activity biosensor in transmigrating T cells, we find that RhoA is locally and

151 nced, regardless of expression of PECAM-1 on transmigrating T cells.

152 More E. chaffeensis-infected monocytes transmigrated than uninfected monocytes, whereas A. phag

153 Notably, blood precursors do not transmigrate the cortex in an undifferentiated state, bu

154 How such an exit is achieved and how cells transmigrate the distinct endothelium of lymphatic vesse

155 ion of choroidal endothelial cells (CECs) to transmigrate the retinal pigment epithelial (RPE) monola

156 d permeability to low-density lipoprotein or transmigrating THP-1 cells.

157 bility of melanoma cells to adhere to and to transmigrate through a monolayer of endothelial cells la

158 Studies have shown that MKs may transmigrate through bone marrow endothelial cells (BMEC

159 matrix) and acquire increased proficiency to transmigrate through endothelial barrier (an obligatory

160 Whether leukocytes can transmigrate through endothelial cells, rather than betw

161 ntly interact with endothelial selectins and transmigrate through endothelial monolayers in vitro.

162 ls migrate up a gradient of the drug CNO and transmigrate through endothelial monolayers.

163 sical populations demonstrated an ability to transmigrate through endothelial monolayers.

164 infected macrophages and lymphocytes did not transmigrate through intact adult oral epithelia.

165 ted the ability of pneumococci to invade and transmigrate through monolayers of rat and human brain m

166 Macrophages transmigrate through the blood brain barrier during HIV-

167 r leukocytes to counteract the shear stress, transmigrate through the endothelial layer, and move tow

168 rved that these T cells can be recruited and transmigrate through vascular and bone marrow endotheliu

169 Neutrophils transmigrated through our model toward airway fluid from

170 Electron microscopy of the cells that transmigrated through the BMEC monolayers in response to

171 n of adherent cells rolled, and the majority transmigrated through the endothelial cell monolayer.

172 y function to maintain neutrophils that have transmigrated through the epithelium in close contact wi

173 olin-1 to the endothelial basal membrane and transmigrated through transcellular passages formed by a

174 ransmission electron microscopy that E. coli transmigrates through BMEC in an enclosed vacuole withou

175 A better understanding of how B. burgdorferi transmigrates through dermal and tissue vascular barrier

176 ming firmly adherent on activation, and then transmigrates through the endothelium.

177 However, the relative number of transmigrated to adherent T cells (i.e., the efficiency

178 Cells transmigrating to the H4R agonist, but not H1R, were ske

179 ed us to decipher the detailed morphology of transmigrating tumor cells and associated endothelial ce

180 istribution of LFA-1 on neutrophils actively transmigrating tumor necrosis factor-alpha-activated hum

181 abilized, and the number of neutrophils that transmigrated was increased 10-fold.