ライフサイエンスコーパス: transposable element

1 ticated loss-of-shattering allele SiLes1-TE (transposable element).

2 to genomic rearrangements likely caused by a transposable element.

3 umerous parallel mutations, many mediated by transposable elements.

4 by PHE1 have been distributed by RC/Helitron transposable elements.

5 methylation of key regulators of meiosis and transposable elements.

6 ssociated with transcriptional repression of transposable elements.

7 is indicated a marked loss of methylation of transposable elements.

8 the transcriptional regulation of genes and transposable elements.

9 well as a common ancestral role in silencing transposable elements.

10 nal and DNA methylation changes at genes and transposable elements.

11 ubstantial portion of sMHSs are derived from transposable elements.

12 ions are largely attributable to activity of transposable elements.

13 he capture and movement of gene fragments by transposable elements.

14 erspersed repeats reflecting the activity of transposable elements.

15 A large majority of new enhancers comprise transposable elements.

16 ive with 74.4% of its content in the form of transposable elements.

17 onal splicing in order to detect and silence transposable elements.

18 c changes in methylation mainly occur within transposable elements.

19 e organized into large arrays interrupted by transposable elements.

20 ells activate expression of primate-specific transposable elements.

21 ciated with the transcriptional silencing of transposable elements.

22 uarius silence overlapping sets of genes and transposable elements.

23 f bacterial communities, and contain tens of transposable elements.

24 rity of the animal germline from deleterious transposable elements.

25 lly when they involve sequences derived from transposable elements.

26 iwi ribonucleoproteins (piRNPs) that silence transposable elements.

27 motif, which is prevalent for both genes and transposable elements.

28 l for the methylation and silencing of young transposable elements.

29 (HGT) mediated by plasmids and plasmid-borne transposable elements.

30 preference for certain superfamilies of DNA transposable elements.

31 ct the transcriptional activity of genes and transposable elements.

32 annotated (773.104 Mbp), with more than 64% transposable elements.

33 H1-bound genes, but only weakly de-represses transposable elements.

34 ected DNA methylation silences young, active transposable elements(2-4).

35 ng RNAs (piRNAs) instruct DNA methylation of transposable elements(3,5).

36 gration sites of retroviruses(2-6) and other transposable elements(7-9), and it has been suggested th

37 n tandemly repeated cis sequences flanking a transposable element (a miniature inverted repeat transp

38 Mutator-like transposable elements, a class of DNA transposons, exist

39 r levels of gene expression, higher rates of transposable element accumulation, more small interferin

40 the genome revealed more than 130,000 intact transposable elements, allowing us to identify transposa

41 Transposable elements, also known as transposons, are no

42 H. bogdanii had been interrupted by a native transposable element and was surrounded by about 70 kbp

43 ymbiosis-induced genes, (4) proliferation of transposable elements and (5) divergent genetic innovati

44 ain transcriptional homeostasis by silencing transposable elements and aberrant intragenic transcript

45 lay faster evolutionary rates, lie closer to transposable elements and are less likely to be syntenic

46 mosome painting revealed the distribution of transposable elements and differentiated chromosome bloc

47 lie several aspects of gene regulation, with transposable elements and disease-associated variants en

48 and other low-complexity regions, as well as transposable elements and endogenous viruses.

49 A small number of transposable elements and genes had reduced DNA methylat

50 lay a crucial role in genome defense against transposable elements and guide Argonaute proteins to na

51 sands of circularly excised Tc1/mariner-type transposable elements and high confidence non-repetitive

52 le germline, misdirects the RNAi response to transposable elements and impairs TEI.

53 residues regulates gene expression, silences transposable elements and influences genome stability.

54 We emphasize the role of transposable elements and other repeat sequences in the

55 de some examples with sequence similarity to transposable elements and other sequences present in the

56 structural and functional annotations (e.g., transposable elements and repetitive sequences).

57 over long genomic distances, associated with transposable elements and subtelomeric regions, conserve

58 eading to transcriptional activation of some transposable elements and the inability to initiate tran

59 ed high methylation levels in both genes and transposable elements, and a prevalence of methylated ov

60 are observed for complete assembly of genes, transposable elements, and highly repetitive genomic fea

61 annotated genes, novel transcribed regions, transposable elements, and microbial species.

62 histone methylation are targeted to viruses, transposable elements, and some transgenes.

63 Transposable elements are abundant in the human genome,

64 , although a few upregulated transcripts and transposable elements are associated with altered small

65 ic tools and mutagenesis strategies based on transposable elements are currently under development wi

66 PIWI-interacting small RNAs (piRNAs) against transposable elements are mainly produced from the ~180-

67 Transposable elements are major evolutionary forces whic

68 Transposable elements are one of the major contributors

69 undescribed replicon genes, and to identify transposable elements as the main drivers of HGT at broa

70 is associated with genome changes driven by transposable elements, as a response to imbalances betwe

71 Transposable elements associated with siRNA clusters had

72 , revealing a differential complexity in the transposable element biology of complex systems not prev

73 diate transcriptional silencing of genes and transposable elements, but how they interact is unclear.

74 The optimized insertion of transposable elements by guide RNA-assisted targeting (I

75 (RIP) mutation in Neurospora crassa degrades transposable elements by targeting repeats with C->T mut

76 iRNA) pathway is vital for the regulation of transposable elements, by inducing transcriptional silen

77 Transposable elements can drive genome evolution, but th

78 of specific classes of evolutionarily young transposable elements can lead to activation of the inna

79 GRF also detects DNA or RNA transposable elements characterized by these repeats in

80 les with promise as aging modulators include transposable elements, circRNAs and the mitochondrial tr

81 d noise in terms of length, number of exons, transposable element composition, and sequence conservat

82 Here, we identify the piggyBac transposable element derived 5 (PGBD5) gene as encoding

83 encing embryonic, nonrenal lineage genes and transposable elements, DNMT1-mediated cytosine methylati

84 wing piRNA-directed DNA methylation of mouse transposable elements), DNMT3A/B should have been DNMT3C

85 We have used the newly engineered transposable element Dsg to tag a gene that gives rise t

86 the dynamic and stage-specific regulation of transposable elements during human prospermatogonial spe

87 Three groups of Tn7-like transposable elements encode 'minimal' type I CRISPR-Cas

88 re tool that provides accurate estimation of transposable element expression (retrotranscriptome) res

89 d recombination, as well as genes regulating transposable element expression.

90 The other is an LTR/Gypsy transposable element family member, which generates long

91 copy, and phenotypical characterization of a Transposable Element from Nicotiana tabacum (Tnt1) inser

92 omains yet dispensable for silencing of most transposable elements; H1 depletion affects nucleosome d

93 ylation analysis of non-reference and mobile transposable elements has only recently been performed,

94 Transposable elements have generated an important number

95 However, H1 loss strongly activates transposable elements hypomethylated through mutation of

96 re associated with miniature inverted-repeat transposable elements, imprinted differentially methylat

97 nd H3K27me3 co-occur at multiple families of transposable elements in an Ezl1-dependent manner.

98 Bot1 (Brassica oleracea transposon 1) CACTA transposable elements in Brassica oleracea, but were los

99 Physiology or Medicine for her discovery of transposable elements in maize.

100 re the smallest but most abundant autonomous transposable elements in prokaryotic genomes, which play

101 Here, based on analysis of transposable elements in the allotetraploid goldfish gen

102 (piRNAs) act as an immune system to suppress transposable elements in the animal gonads.

103 The role of transposable elements in the expansion of nucleotide-bin

104 The piRNA pathway represses transposable elements in the gonads and thereby plays a

105 ion of alleles lacking the insertions of two transposable elements in the regulatory region of KNR6 c

106 rphism (SSAP) to compare the dynamics of six transposable elements in these allopolyploids, their dip

107 ral loci, including protein coding genes and transposable elements, in diverse chromatin contexts.

108 , they induce the expression of thousands of transposable elements including endogenous retroviruses

109 Transposable elements, including endogenous retroviruses

110 fied host variants that affect expression of transposable elements, independent of their copy number,

111 We found a miniature inverted-repeat transposable element insertion in the promoter region of

112 ociated with this ALHS in Colias crocea to a transposable element insertion located downstream of the

113 Finally, genetic variation based on the transposable element insertion pattern was investigated

114 ed epiTEome, a program that detects both new transposable element insertion sites and their methylati

115 riation, including tandem duplications and a transposable element insertion that amplifies the expres

116 posable element (a miniature inverted repeat transposable element) insertion in the SbMATE promoter,

117 enomic organization, transcription patterns, transposable element insertions and phylogenetic analyse

118 brates solves the problem of gene-disrupting transposable element insertions by splicing them out at

119 Whereas transposable element insertions have been known to cause

120 Polymorphic transposable element insertions in promoter sequences co

121 nts lack this R domain due to insertion of a transposable element into the 3' end of ppzA We demonstr

122 rotein expression of the Gag sequence of the transposable element intracisternal A-particle.

123 ich MIWI2 directs the de novo methylation of transposable elements is poorly understood, although cen

124 Transcription of transposable elements is tightly regulated to prevent ge

125 nscription of integrated DNA from viruses or transposable elements is tightly regulated to prevent pa

126 The hopper hAT-family transposable element isolated from the Oriental fruit fl

127 ansposable elements, allowing us to identify transposable element lineage expansions that are unique

128 oids and quantitative imbalances in parental transposable element loads supports the genome shock hyp

129 Transposable elements make up half of the mammalian geno

130 Transposable elements may also be at the origin of impor

131 avirulent gene-containing SM cluster through transposable element-mediated whole-cluster duplication

132 regions that are non-genic, pericentromeric, transposable elements; methylated; and with low recombin

133 The insertion is a miniature inverted repeat transposable element (MITE) that contains two additional

134 found that Tourist-miniature inverted-repeat transposable element (MITE)-derived small interfering RN

135 Miniature inverted repeat transposable elements (MITEs) are prevalent in eukaryoti

136 TIR transposons known as miniature inverted transposable elements (MITEs), and Helitrons.

137 ansposons, such as miniature inverted-repeat transposable elements (MITEs), long terminal repeat (LTR

138 Stowaway family of miniature inverted-repeat transposable elements (MITEs).

139 The correlation between transposable element mobilisation in allopolyploids and

140 Transposable element mobilisation is not concomitant wit

141 Transposable-element mRNAs are also produced, but discon

142 Mutator-like transposable elements (MULEs) are widespread across fung

143 ed abortion is thus unlikely to be caused by transposable elements or imprinted gene misregulation, a

144 h highly derived roles in the suppression of transposable elements or meiotic drive.

145 major influence in population genetics, and transposable elements play a key role in pan-genome evol

146 ylation levels has been limited to reference transposable element positions.

147 more gene disruption, loss, conversion, and transposable element proliferation, and having reduced g

148 is and shows an increased genome size due to transposable elements proliferation.

149 RNAs) of 21-35 nucleotides in length silence transposable elements, regulate gene expression and figh

150 as investigated to elucidate the features of transposable elements related to blue egg shell formatio

151 -associated siRNAs indicates a strengthen of transposable element repression during the allopolyploid

152 factors, including deleterious mutations or transposable elements resulting from relaxed selection,

153 y and illustrate how epigenetic silencing of transposable elements rewires host gene expression progr

154 CE1 cluster is located in a newly formed and transposable element-rich region.

155 These results suggest that Xist may coopt transposable element RNA-protein interactions to repurpo

156 his method to the study of the spread of the transposable elements ROO, GYPSY and DM412 on a chromoso

157 gnificantly hypomethylated and include fewer transposable element sequences relative to non-NAT genes

158 percent of the human genome is comprised of transposable element sequences, and the most abundant cu

159 various levels using boolean operators (e.g. transposable elements, snakes, carotenoid content, Doebl

160 a small set of lncRNAs appears enriched for transposable elements suggesting a selective pressure ac

161 to full-length and transcriptionally active transposable elements, suggesting that these pathways ar

162 production can either facilitate or restrain transposable element (TE) accumulation by providing TEs

163 eages have experienced differential rates of transposable element (TE) accumulation, which would be p

164 The regulation of transposable element (TE) activity by small RNAs is a ub

165 Transposable element (TE) activity is repressed in anima

166 In contrast, transposable element (TE) annotations are rudimentary, c

167 tion is frequently associated with increased transposable element (TE) content.

168 Transposable element (TE) derived sequences are known to

169 igated the relationships of gene expression, transposable element (TE) distribution and small RNA tar

170 Evidence is rapidly mounting that transposable element (TE) expression and replication may

171 kness and monitored their effect on gene and transposable element (TE) expression with transcriptome

172 r tool with other approaches for quantifying transposable element (TE) expression, and found that Tel

173 new tool, ERVcaller, to detect and genotype transposable element (TE) insertions, including ERVs, in

174 including expansions of microsatellites and transposable element (TE) insertions.

175 mined gene expression, gene methylation, and transposable element (TE) methylation in a natural, <140

176 We found transposable element (TE) mobility in Schizosaccharomyce

177 to specifically target and cleave endogenous transposable element (TE) mRNAs produced from transcript

178 has allowed for population-level surveys of transposable element (TE) polymorphism via split alignme

179 etic silencing of a new transgene, virus, or transposable element (TE) remains enigmatic.

180 hers rely on generalized methods to quantify transposable element (TE) RNA expression, such as RT-qPC

181 r Cnr) had insertions of four related 138 bp transposable element (TE) sequences at precisely the sam

182 omplex transcriptional control mediated by a transposable element (TE) that restricts its expression

183 Loss of PAF1 suppresses endogenous transposable element (TE) transcript maturation, whereas

184 nt pollen shows a strong overaccumulation of transposable element (TE) transcripts, yet a depletion o

185 IV (Pol IV) is required for the formation of transposable element (TE)-derived small RNA transcripts.

186 Transposable elements (TE) comprise roughly half of the

187 tivation of a subset of evolutionarily young transposable elements (TE), including endogenous retrovi

188 By combining analysis of both genes and transposable elements (TEs) affected by CNVs, we reveale

189 ective constraint acting on lineage-specific transposable elements (TEs) and a set of 25 specific tra

190 Current assemblies traverse transposable elements (TEs) and provide an opportunity f

191 Transposable elements (TEs) and repetitive DNA make up a

192 Coevolution between transposable elements (TEs) and their hosts can be antag

193 latory variation, whereas presence of nearby transposable elements (TEs) and tissue specificity of ex

194 Transposable elements (TEs) are a prolific source of tig

195 Transposable elements (TEs) are a significant component

196 Transposable elements (TEs) are an abundant and rich gen

197 Transposable elements (TEs) are an integral part of the

198 Transposable elements (TEs) are extremely abundant in co

199 Transposable elements (TEs) are genomic parasites that a

200 Transposable elements (TEs) are interspersed repeat sequ

201 Transposable elements (TEs) are mobile DNA sequences tha

202 Transposable elements (TEs) are mobile DNA sequences tha

203 Transposable elements (TEs) are mobile genetic elements

204 Transposable elements (TEs) are mobile genetic elements,

205 Transposable elements (TEs) are mobile genetic parasites

206 Transposable elements (TEs) are mobile parasitic sequenc

207 In the plant male germline, transposable elements (TEs) are reactivated in the compa

208 Transposable elements (TEs) are selfish genetic units th

209 Transposable elements (TEs) are thought to have helped e

210 Transposable elements (TEs) are ubiquitous components of

211 Transposable elements (TEs) are ubiquitous DNA segments

212 Transposable elements (TEs) are ubiquitous genomic featu

213 Transposable elements (TEs) are uniquely equipped to dep

214 In many eukaryotic genomes, transposable elements (TEs) are widely distributed and o

215 Transposable elements (TEs) are widespread genomic paras

216 It is well documented that transposable elements (TEs) can regulate the expression

217 Transposable elements (TEs) classification is an essenti

218 Expansion of transposable elements (TEs) coincides with evolutionary

219 Transposable elements (TEs) compose nearly half of mamma

220 Transposable elements (TEs) comprise a large proportion

221 Genomic transposable elements (TEs) comprise nearly half of the

222 Transposable elements (TEs) comprise nearly half of the

223 Transposable elements (TEs) constitute a significant thr

224 Transposable elements (TEs) contribute to the large amou

225 Transposable elements (TEs) drive genome evolution and a

226 Transposable elements (TEs) have deposited functional re

227 Although transposable elements (TEs) have long been recognized to

228 ve shown that heat shock stress may activate transposable elements (TEs) in Drosophila and other orga

229 rveillance systems constrain the activity of transposable elements (TEs) in host genomes.

230 Recent research has uncovered roles for transposable elements (TEs) in multiple evolutionary pro

231 n this study, we focused on the evolution of transposable elements (TEs) in relation to the genome si

232 As) instruct DNA methylation of young active transposable elements (TEs) in the male germline.

233 Most transposable elements (TEs) in the mouse genome are heav

234 Transposable elements (TEs) influence the evolution of n

235 Variation in the presence or absence of transposable elements (TEs) is a major source of genetic

236 In eukaryotes, aberrant expression of transposable elements (TEs) is detrimental to the host g

237 The silencing of repetitive transposable elements (TEs) is ensured by signal amplifi

238 Silencing of transposable elements (TEs) is established by small RNA-

239 Transposable elements (TEs) make up a large and rapidly

240 Transposable elements (TEs) make up a large proportion o

241 Transposable elements (TEs) make up half of mammalian ge

242 Transposable elements (TEs) regularly capture fragments

243 Transposable elements (TEs) represent the single largest

244 The excision and reintegration of transposable elements (TEs) restructure their host genom

245 Transposable elements (TEs) shape genome evolution throu

246 rt Interspersed Nuclear Elements (SINEs) are transposable elements (TEs) that amplify through a copy-

247 (piRNAs) protect the germ line by targeting transposable elements (TEs) through the base-pair comple

248 Co-option of transposable elements (TEs) to become part of existing o

249 l consequence of this is the reactivation of transposable elements (TEs) which could stimulate the im

250 ge portions of eukaryotic genomes consist of transposable elements (TEs), and the establishment of tr

251 recognition and transcriptional silencing of transposable elements (TEs), consistent with an 'arms ra

252 We map the evolutionary trajectories of transposable elements (TEs), developmental genes and sex

253 The majority of human KRAB-ZFPs bind transposable elements (TEs), however, since most TEs are

254 n at CHH sites is kept high, particularly at transposable elements (TEs), in the vegetative SAM relat

255 Newly evolved CREs are enriched in young transposable elements (TEs), including Long-Terminal-Rep

256 hroughout the entire seed, targets primarily transposable elements (TEs), is maintained during endore

257 hypomethylation of protein-coding genes and transposable elements (TEs), preferentially those adjace

258 Transposable elements (TEs), the movement of which can d

259 While many CTCF binding sites fall within transposable elements (TEs), their contribution to 3D ch

260 ation, little is known about their effect on transposable elements (TEs), which make up nearly half o

261 ied source of transcriptional regulators are transposable elements (TEs), whose aberrant usage could

262 lity requires control over the expression of transposable elements (TEs), whose activity can have sub

263 Half the human genome is made of transposable elements (TEs), whose ongoing activity cont

264 eliminated sequences (IESs)-many related to transposable elements (TEs)-become transcriptionally act

265 n germ cells during development de-represses transposable elements (TEs).

266 riants, many attributable to the movement of transposable elements (TEs).

267 ghlighting the diversity and distribution of transposable elements (TEs).

268 ethylation is a major silencing mechanism of transposable elements (TEs).

269 rity of HTs reported so far are transfers of transposable elements (TEs).

270 ads to risk of transcriptional activation of transposable elements (TEs).

271 elanogaster, where it acts to silence active transposable elements (TEs).

272 ised annotation of genome components such as transposable elements (TEs).

273 of this variation is due to the presence of transposable elements (TEs).

274 f MNase-sensitive regions are located within transposable elements (TEs).

275 RA5 primarily reflected the insertion of two transposable elements (TEs): the T1 DNA transposon and t

276 INE-1 (long interspersed element 1, L1) is a transposable element that has extensively colonized the

277 Furthermore, we discovered a transposable element that resides immediately upstream o

278 of genomic sequences, some with homology to transposable elements, that have increased in copy numbe

279 utilize small RNAs called piRNAs to silence transposable elements, thereby protecting germline integ

280 A clusters resulted in lower activity of the transposable elements through DNA methylation in the hyb

281 egulation of genes derived from Mutator-like transposable elements, thus contributing to the evolutio

282 It has few transposable elements, tiny intergenic regions, and is r

283 predominant plasmid (pKpQIL), and a specific transposable element (Tn4401, 10 kb).

284 odel whereby tethering of MIWI2 to a nascent transposable element transcript recruits repressive chro

285 onents regulate precursor mRNA splicing of P-transposable element transcripts in vivo, leading to the

286 RNAs are proposed to tether MIWI2 to nascent transposable element transcripts; however, the mechanism

287 many examples, including the suppression of transposable elements, uniparental inheritance of mitoch

288 contrast to the precise circular excision of transposable elements, we report widespread heterogeneit

289 ulators of retrotransposition and endogenous transposable elements were dysregulated following MIA, p

290 preferentially enriched on edges of silenced transposable elements, where Pol V transcribes into TEs.

291 tion levels in both protein-coding genes and transposable elements, whereas the resistant line showed

292 the accumulation of toxic transcripts of Alu transposable elements, which activate the NLRP3 inflamma

293 ith heat-induced mobilization of Tc1/mariner transposable elements, which are known to cause DSBs and

294 The cells contain tens of transposable elements, which likely cause the unpreceden

295 in global transcriptional hyperactivation of transposable elements with modest effects on protein-cod

296 We also found evidence of the association of transposable elements with SLF pseudogenes.

297 Decitabine globally reactivated multiple transposable elements, with activation of the dsRNA sens

298 An intronic, transposable element within SMOC2 promotes the utilizati

299 that LTR/Gypsy and LTR/Copia were two major transposable elements within the intronic polyadenylatio

300 or this expansion is an arms race to silence transposable elements yet it remains poorly understood h