ライフサイエンスコーパス: transverse relaxation

1 ms originates from signal losses due to fast transverse relaxation.

2 In perfused myocardium the field-dependent transverse relaxation analysis of the deoxy Mb proximal

3 of MR signal, the latter contributes to its transverse relaxation and causes the anisotropy of MR si

4 2) into water significantly reduces the (1)H transverse relaxation coefficient (T(2)).

5 The proton transverse relaxation constant (T2) using both MR imagin

6 Longitudinal and transverse relaxation data and steady-state (1)H- (15)N

7 The water and fat proton signals in the transverse relaxation decay curves have been deconvolute

8 ation data and the Carr-Purcell-Meiboom-Gill transverse relaxation dispersion measurements, suggest t

9 aracterization by more demanding techniques (transverse relaxation dispersion, saturation transfer, a

10 transition, the lipid (1)H signals have slow transverse relaxation, enabling filtering experiments as

11 set, freeing up the entire row dimension for transverse relaxation encoding with J-refocusing.

12 ls, and markedly broadened dynamic range for transverse relaxation encoding.

13 ribe that the PSR filter is dominated by the transverse relaxation enhancement (R(2p)) experienced by

14 ide chain generates large distance-dependent transverse relaxation enhancements, analogous to those o

15 15N NMR transverse relaxation experiments reveal that the acid-d

16 S) technologies, whose approach to measuring transverse relaxation has not changed for decades.

17 and alteration of magnetic resonance imaging transverse relaxation in late-life cognitive decline.

18 ncentration-dependent relaxation dispersion, transverse relaxation in the rotating frame, and exchang

19 pendent exchange-induced chemical shifts and transverse relaxation in the rotating frame.

20 tter chemical concentrations and altered Cho transverse relaxation, in a pattern distinct from that i

21 Although molecular transverse relaxation informs local cellular microenviro

22 ration of ex vivo magnetic resonance imaging transverse relaxation is associated with late-life cogni

23 structure-activity relationship studies and transverse relaxation measurements by nuclear magnetic r

24 Transverse relaxation measurements of the (19)F nucleus,

25 Low field NMR T2 transverse relaxation measurements were performed on mus

26 Incorporation of the water attenuation by transverse relaxation method for the complete and select

27 t were detected by exchange contributions to transverse relaxation of both C epsilon and C alpha.

28 , but decreased the exchange contribution to transverse relaxation of the backbone.

29 Based on a combination of methyl transverse relaxation optimized (TROSY) NMR spectroscopy

30 Here, we present methyl-transverse relaxation optimized NMR spectroscopy (methyl

31 Here, we use (15)N(z)-exchange transverse relaxation optimized NMR spectroscopy to char

32 omplex determined by a combination of methyl-transverse relaxation optimized nuclear magnetic resonan

33 (1)H-(15)N transverse relaxation optimized spectra of uniformly lab

34 NMR transverse relaxation optimized spectroscopic analysis o

35 combination of X-ray crystallography, methyl-transverse relaxation optimized spectroscopy (methyl-TRO

36 Here we use methyl transverse relaxation optimized spectroscopy (methyl-TRO

37 The labels when coupled with the transverse relaxation optimized spectroscopy (TROSY) ena

38 Specific methyl labeling schemes and transverse relaxation optimized spectroscopy (TROSY) has

39 resonance (NMR) technique based on modified transverse relaxation optimized spectroscopy (TROSY) has

40 ent binder to KRas(G12D) and used (1)H (15)N transverse relaxation optimized spectroscopy (TROSY) het

41 using mutant subunits, we performed a methyl-transverse relaxation optimized spectroscopy (TROSY) NMR

42 e model with biochemical and solution methyl-transverse relaxation optimized spectroscopY (TROSY) NMR

43 abeling technique in combination with methyl-transverse relaxation optimized spectroscopy (TROSY) NMR

44 evisiae Rev1 and demonstrate with the use of transverse relaxation optimized spectroscopy (TROSY) NMR

45 e analyzed its Ca2+-binding properties using transverse relaxation optimized spectroscopy (TROSY)-bas

46 We have used transverse relaxation optimized spectroscopy (TROSY)-bas

47 Our methyl-transverse relaxation optimized spectroscopy (TROSY)-bas

48 Using methyl transverse relaxation optimized spectroscopy (TROSY)-bas

49 Here, using methyl-transverse relaxation optimized spectroscopy (TROSY)-bas

50 We re-engineered the basic transverse relaxation optimized spectroscopy experiment

51 es sparse distance restraints obtained using transverse relaxation optimized spectroscopy experiments

52 (13)C-Methyl-transverse relaxation optimized spectroscopy measurement

53 Application of the transverse relaxation optimized spectroscopy sequence re

54 We highlight methyl-TROSY (transverse relaxation optimized spectroscopy) NMR, which

55 ing strategy, biochemical assays, and methyl-transverse relaxation optimized spectroscopy-based NMR s

56 nation of hydrodynamics measurements, methyl-transverse relaxation optimized spectroscopy-based solut

57 sured in both apo- and holo-RXRalpha LBDs by transverse relaxation optimized spectroscopy-Carr-Purcel

58 transverse relaxation optimized spectroscopy-Carr-Purcel

59 s, was investigated both by conventional and transverse relaxation optimized spectroscopy-type hetero

60 Transverse relaxation optimized spectroscopy-type NMR ex

61 We used multidimensional, transverse relaxation-optimized NMR experiments to assig

62 Here, we used a combination of methyl-transverse relaxation-optimized NMR spectroscopy, protei

63 Using methyl transverse relaxation-optimized NMR spectroscopy, we dem

64 Using methyl transverse relaxation-optimized nuclear magnetic resonan

65 The development of methyl-transverse relaxation-optimized spectroscopy (methyl-TRO

66 Here, we use methyl-Transverse Relaxation-Optimized Spectroscopy (TROSY) and

67 ry, surface plasmon resonance and (1)H-(15)N transverse relaxation-optimized spectroscopy (TROSY) NMR

68 Transverse relaxation-optimized spectroscopy (TROSY) NMR

69 bservation that high-quality 2D [(15)N,(1)H]-transverse relaxation-optimized spectroscopy (TROSY) spe

70 We present the first steps in applying transverse relaxation-optimized spectroscopy (TROSY) tec

71 Methyl transverse relaxation-optimized spectroscopy (TROSY)-bas

72 Two-dimensional transverse relaxation-optimized spectroscopy 15N-1H HSQC

73 s observation from MD is supported by methyl-transverse relaxation-optimized spectroscopy NMR data, w

74 ional (1)H-(13)C(F) correlation spectra with transverse relaxation-optimized spectroscopy selection o

75 sperse (19)F resonances in a two-dimensional transverse relaxation-optimized spectroscopy spectrum.

76 e demonstrate the application of (19)F-(13)C transverse relaxation-optimized spectroscopy to investig

77 This paper describes two transverse-relaxation-optimized (TRO) (15)N-filtered PFG

78 rties of CA-Ile and -Met methyl groups using transverse-relaxation-optimized NMR spectroscopy to expl

79 ure the effect of conformational exchange on transverse relaxation parameters, namely Carr-Purcell-Me

80 In intrinsically disordered proteins, slow transverse relaxation permits measurement of (3)J(C'C')

81 s, given their high sensitivity and superior transverse relaxation properties, compared to single flu

82 the anesthetic binding but shows an elevated transverse relaxation (R(2)) rate.

83 rameters such as diffusion coefficients (D), transverse relaxation (R(2)), and structural similarity.

84 For this, we use advanced methods such as transverse relaxation (R(2)), diffusion measurements, sa

85 e, 2 years apart, by using phase imaging and transverse relaxation (R2*) mapping at 4.7 T.

86 in the chemical exchange contribution to the transverse relaxation rate ( R ex) values, relative to t

87 = 171) 14-93 years of age were examined with transverse relaxation rate (R(2)) and four diffusion ten

88 Earlier, our group reported that this transverse relaxation rate (R(2)) can be measured by an

89 The transverse relaxation rate (R(2)) for beta37Trp can serv

90 In thoracoabdominal metastases, tumor transverse relaxation rate (R*(2)) was normalized to the

91 With these data plus the enhancements in transverse relaxation rate (R2) for the other eight prot

92 An exchange contribution was detected in the transverse relaxation rate (R2) of all residues.

93 The target was a composite measure of the transverse relaxation rate (R2) that was associated with

94 rameters [longitudinal relaxation rate (R1), transverse relaxation rate (R2), and heteronuclear nucle

95 Estimates of the apparent transverse relaxation rate (R2*) can be used to quantify

96 between the susceptibility and the effective transverse relaxation rate (R2*) indicated that localize

97 proton density (PD), longitudinal (R1), and transverse relaxation rate (R2*) with 1.6 mm isotropic r

98 xation (R1)) and iron content (via effective transverse relaxation rate (R2*)) was used to track micr

99 The longitudinal relaxation rate (T(1)) and transverse relaxation rate (T(2)) data give mutually con

100 n point spread functions associated with the transverse relaxation rate 1/T(2)(*).

101 In water NMR (wNMR), the use of the water transverse relaxation rate [R(2)((1)H(2)O)] has been pre

102 axometry (longitudinal relaxation rate [R1], transverse relaxation rate [R2], and proton density [PD]

103 endence of the exchange contributions to the transverse relaxation rate constant shows approximately

104 longitudinal relaxation rate constants (R1), transverse relaxation rate constants (R2), and steady-st

105 easuring pH-dependent (15)N, (13)C, and (1)H transverse relaxation rate constants for 5 nuclei in eac

106 ntifying R2' (reversible contribution to the transverse relaxation rate from local field inhomogeneit

107 les, which induce substantial changes in the transverse relaxation rate of proton nuclear magnetic re

108 The sensor measures the transverse relaxation rate of water molecules in biologi

109 The transverse relaxation rate of water protons, R(2)((1)H(2

110 ly by examining the dependence of the proton transverse relaxation rate on the spin-locking field str

111 calibration curve (R(2) > 0.999) between the transverse relaxation rate R(2) and iron concentration f

112 he affinity range of low muM to low mM using transverse relaxation rate R(2) as the observable parame

113 Water proton transverse relaxation rate R(2)((1)H(2)O) measurements b

114 nce (15)N longitudinal relaxation rate R(1), transverse relaxation rate R(2), and steady-state {(1)H}

115 novel approach that employs the water proton transverse relaxation rate R2((1)H2O).

116 longitudinal relaxation rate R1 (1/T1), (2) transverse relaxation rate R2* (1/T2*), and (3) Magnetiz

117 hibit a 20-fold increase in longitudinal and transverse relaxation rate values over the conventional

118 nificant exchange R(ex) contributions to the transverse relaxation rate were detected for most of the

119 which correlates the chemical shift with the transverse relaxation rate, allows for the simultaneous

120 tact bound states with a very fast effective transverse relaxation rate, indicative of side-chain-med

121 , under nonflow conditions, the water proton transverse relaxation rate, R(2)((1)H(2)O), is sensitive

122 dipyridamole-induced change in the apparent transverse relaxation rate, R2*, which correlates with h

123 R2, the true transverse relaxation rate, was negatively correlated wi

124 a measurable change in spin-spin relaxation (transverse relaxation) rate in proton nuclear magnetic r

125 otofibril-bound species in the form of (15)N transverse relaxation rates ((15)N-R(2)) and exchange ki

126 d loop regions and by the enhanced spin-spin transverse relaxation rates (R(2)) observed in the trans

127 e concentration of paramagnetic ions and the transverse relaxation rates (R(2)) of the solvent proton

128 sistent differences were found for effective transverse relaxation rates (R(2)*).

129 DDADP2-, and Mn(II)PO4(-)) on F- ion 19F NMR transverse relaxation rates (R2 = 1/T2) were studied in

130 ternal motions, reflected in unusually large transverse relaxation rates (R2), was also largely unaff

131 talbumin have been characterized using (15)N transverse relaxation rates (R2).

132 Nepsilon-H resonance and the amide nitrogen transverse relaxation rates (R2s) for varying pH values

133 We have also measured NMR longitudinal and transverse relaxation rates and (15)N-(1)H NOE enhanceme

134 at pH 5.0 and 2.5: 15N NMR longitudinal and transverse relaxation rates and 15N-1H nuclear Overhause

135 e measured and analyzed 15N longitudinal and transverse relaxation rates and [1H]-15N heteronuclear O

136 an analysis of nitrogen-15 longitudinal and transverse relaxation rates and amide nitrogen-proton nu

137 ch enable rapid and reliable measurements of transverse relaxation rates and diffusion coefficients w

138 Using measurement of chemical shifts, (15)N transverse relaxation rates and sedimentation coefficien

139 try measures, including the longitudinal and transverse relaxation rates and the myelin water fractio

140 Transverse relaxation rates are measured simultaneously

141 Purine H8 transverse relaxation rates are reduced ~20-fold with ri

142 rates were extracted by examining the (15)N transverse relaxation rates as a function of CPMG delay

143 es of TC14 by measuring 15N longitudinal and transverse relaxation rates as well as [1H-15N] heteronu

144 We measured whole-brain longitudinal and transverse relaxation rates as well as the myelin water

145 ddition, the difference (DeltaR(2)) in (15)N transverse relaxation rates between this sample and a co

146 The water proton longitudinal and transverse relaxation rates correlated well with GAG and

147 Amide nitrogen transverse relaxation rates for GB1 in the folded state

148 ng was also suggested by a comparison of the transverse relaxation rates for hRPA70(1-326) and one of

149 hemical shift perturbation mapping and (15)N transverse relaxation rates for intact cardiac troponin

150 ater-exchange rates and various types of 15N transverse relaxation rates for these NH3 groups, reveal

151 The phenomenon can be observed in the transverse relaxation rates in water proton magnetic res

152 me, the extent of the observed variations in transverse relaxation rates is consistent with the prese

153 Proton longitudinal and transverse relaxation rates of alphavbeta3-targeted and

154 The Tyr35 --> Gly substitution increased the transverse relaxation rates of more than one third of al

155 concentration, 1H-nuclear magnetic resonance transverse relaxation rates of packed RBCs, and plasma m

156 lution NMR approach in which enhancements of transverse relaxation rates of tail amide and methyl gro

157 can be detected by observing changes in the transverse relaxation rates of the ligand upon binding.

158 ), cerebral blood volume (DeltaCBV/CBV), and transverse relaxation rates of tissue water (T(2)(*) and

159 gens in a liquid mixture have different (1)H transverse relaxation rates R(2)((1)H), forming the basi

160 pology, diffusion, and susceptibility on the transverse relaxation rates R2* and R2.

161 Transverse relaxation rates rapidly increase to ca. 1000

162 flexible, exhibiting cross-peak patterns and transverse relaxation rates that are very similar to tho

163 Previously, we utilized (15)N transverse relaxation rates to demonstrate significant m

164 The 15N longitudinal relaxation rates, 15N transverse relaxation rates, and inverted question mark1

165 with measures of longitudinal and effective transverse relaxation rates, proton density and magnetis

166 on axis order parameters, determined by (2)H transverse relaxation rates, suggest that rigidification

167 the magnetic field dependencies of the (13)C transverse relaxation rates, whereas the tensor orientat

168 rapid loss of spin coherence caused by large transverse relaxation rates.

169 in the wild-type protein displaying enhanced transverse relaxation rates.

170 ement of the paramagnetically enhanced (13)C transverse relaxation rates.

171 undergoing motions revealed by enhanced 15N transverse relaxation rates.

172 t interferes with the extraction of accurate transverse relaxation rates.

173 e NMR spectrum, due to the existence of fast transverse relaxation, related to the large size and exc

174 (15)N transverse relaxation results indicate that residues P(6

175 arge proteins and at very high fields, rapid transverse relaxation severely limits the sensitivity of

176 w-Field Nuclear Magnetic Resonance of proton transverse relaxation signal (T(2)) was monitored in hak

177 Transverse relaxation studies indicated an increase in t

178 solution using (15)N longitudinal (T(1)) and transverse relaxation (T(2)) measurements as well as [(1

179 Gill pulse sequence were used to measure the transverse relaxation (T(2)) of the nucleus and thereby

180 P) including longitudinal relaxation (T(1)), transverse relaxation (T(2)), and (15)N-{(1)H} NOE data

181 Longitudinal relaxation (T(1)), transverse relaxation (T(2)), and the (15)N-[(1)H] NOE w

182 near-infrared (NIR) window and enhanced the transverse relaxation (T2 ) contrast effect, as a result

183 Four MR imaging methods based on transverse relaxation (T2 weighting, R2 mapping, and R2*

184 TD-NMR spectroscopy was used to measure the transverse relaxation time (T(2)) and intensity of proto

185 E values between 60 ms and 270 ms to measure transverse relaxation time (T(2)) in the basal ganglia.

186 gnificant changes in both chemical shift and transverse relaxation time (T(2)) in the presence of E1p

187 , the free MNP(30) left in solution acted as transverse relaxation time (T(2)) signal reporters for S

188 measurement, water status was assessed from transverse relaxation time (T(2)) weighted signals regis

189 ld, created by microstructure, influence the transverse relaxation time (T2) in an orientation-depend

190 Because the magnetic resonance imaging (MRI) transverse relaxation time (T2) of cartilage is sensitiv

191 Quantitatively, transverse relaxation time (T2) of CSS increased non-lin

192 Diffusion tensor imaging and transverse relaxation time (T2) relaxometry were perform

193 netic resonance imaging showed a significant transverse relaxation time (T2) shortening in the pancre

194 The MRI outcomes-fat fraction, transverse relaxation time (T2), and magnetisation trans

195 s) induced by downhill running (DR) by using transverse relaxation time (T2)-weighted magnetic resona

196 Transverse relaxation time (T2)-weighted, diffusion-weig

197 xation in the rotating frame (T1rho) and the transverse relaxation time (T2).

198 tion (FF); multislice spin echo MRI measured transverse relaxation time (T2).

199 y (aw), freezable water content, (1)H proton transverse relaxation time and water self-diffusivity de

200 mension, 11 mm(3)) were applied to determine transverse relaxation time as affected by magnetic field

201 Upon binding, the transverse relaxation time constant (T(2)) of (19)F reso

202 es of maximal cross-sectional area (CSAmax), transverse relaxation time constant (T2), and lipid frac

203 nd 1-year follow-up quantitative MR imaging (transverse relaxation time constant; MRI-T2 ), MR spectr

204 ng for water and metabolite longitudinal and transverse relaxation time constants.

205 re were differences between the frequency or transverse relaxation time of signals for the reference

206 We show an increase in the transverse relaxation time of the stabilized, error-prot

207 We further present 2D images of T1 and the transverse relaxation time T2 of the brain and show that

208 ngle and a time between pulses less than the transverse relaxation time, allowing for thousands of sc

209 e thought to be fundamentally limited by the transverse relaxation time.

210 omplexity, chemical shift overlap, and short transverse relaxation times (associated with slow tumbli

211 mal analysis at 50-70 C were studied through transverse relaxation times (T(2)) measured after Hahn s

212 ysis at 50-70 degrees C were studied through transverse relaxation times (T(2)) measured after Hahn s

213 Serial MRI showed the transverse relaxation times (T(2)) were significantly lo

214 KD was determined by measuring the 19F transverse relaxation times (T2) as a function of isoflu

215 mmonly observed increase in the water proton transverse relaxation times (T2) in magnetic resonance i

216 The monodimensional spectra and transverse relaxation times (T2) of 88 samples, includin

217 The characteristic distribution of transverse relaxation times (T2) within dendrimers (shor

218 ncluding apparent diffusion coefficients and transverse relaxation times as affected by magnetic fiel

219 Transverse relaxation times for Cho, creatine plus phosp

220 We also observe changes in the transverse relaxation times for methionines near regions

221 Transverse relaxation times indicated a lower degree of

222 in-subject coefficients of variation for the transverse relaxation times of glutamate and glutamine,

223 t interactions, precise determination of the transverse relaxation times of molecules with scalar cou

224 The relative intensities and the transverse relaxation times of the NMR signal components

225 l-based nanostructures have longitudinal and transverse relaxation times that are on par with commonl

226 Color-encoded parametric maps of T2* transverse relaxation times were calculated on a pixel-b

227 xperiments when supplemental spin-lattice or transverse relaxation times were employed in the analysi

228 measures changes in spin-spin T(2) magnetic (transverse) relaxation times using a benchtop NMR instru

229 Proton transverse relaxation values for both the water and fat

230 Cheese batches which have lower transverse relaxation values for the water and fat proto

231 Gray matter Cho transverse relaxation was also prolonged for the ASD sam

232 Maps of ex vivo magnetic resonance imaging transverse relaxation were generated using fast spin ech