ライフサイエンスコーパス: trauma

1 sound discrimination, and mitigates acoustic trauma.

2 idered, including antecedent blunt abdominal trauma.

3 generation and functional recovery after CNS trauma.

4 that causes Shock-Induced Endotheliopathy in trauma.

5 PTH-CH that developed within 7 days of head trauma.

6 ts the central nervous system after surgical trauma.

7 ies to improve sepsis care in patients after trauma.

8 that methylation differences preexisted the trauma.

9 d comorbidities in people exposed to complex trauma.

10 tcomes, and reintegration into society after trauma.

11 d 11 patients (64.7%) suffered a high-energy trauma.

12 taract surgery, and glaucoma associated with trauma.

13 = 64, 21.9%) including brain and spinal cord trauma.

14 developing chronic PTSD in the aftermath of trauma.

15 ogy of sepsis in patients hospitalized after trauma.

16 of seroma accumulation, such as infection or trauma.

17 exfoliation, prior vitreoretinal surgery, or trauma.

18 eatment package for managing PTSD in complex trauma.

19 st-established epigenetic risk factor, brain trauma.

20 udies of adults who have experienced complex trauma.

21 BMMSC) for cartilage repair strategies after trauma.

22 cular traction and a remote history of blunt trauma.

23 a risk factor for worse outcomes after brain trauma.

24 leading cause of death and disability due to trauma.

25 occurrences following minor or major corneal trauma.

26 e protocol or had multimorbidity or multiple trauma.

27 en, and 25% had a history of previous ocular trauma.

28 ry (19 of 49 episodes [29%]) and remote head trauma (15 of 49 episodes [23%]).

29 ies of illness (0% vs 6.1%, p = 3.1 x 10 for trauma; 15.0% vs 25.4%, p = 4.4 x 10 for community-acqui

30 d aORs were 2.15 (95% CI 1.72-2.70) for head trauma; 19.3 (95% CI 14.3-26.0) for neurosurgery; 4.61 (

31 ); sequelae of macular edema (3 eyes); blunt trauma (2 eyes); retinal phototoxicity resulting from la

32 comorbidities were noted, including corneal trauma (20%), hyphema (41%), iris trauma (62%), lens exp

33 Blunt trauma (37 eyes) and penetrating injuries (16 eyes) were

34 mon reason for requesting the study was head trauma (40.5%); only 15.6% of these studies showed acute

35 ent of PTSD symptoms upon ED admission after trauma(5).

36 ng corneal trauma (20%), hyphema (41%), iris trauma (62%), lens expulsion (54%), subretinal hemorrhag

37 erral (9.7%), sudden vision loss (9.3%), and trauma (8.0%) were the commonest presenting symptoms.

38 ess of whether it is secondary to early life trauma, a more acute stress response, microbiome alterat

39 This study tested whether childhood trauma, affective lability, and aggressive and impulsive

40 Abusive head trauma (AHT) is the leading cause of infant death and lo

41 egression analysis adjusted for stroke, head trauma, alcohol abuse, and cancer showed 1-year, 2-5 yea

42 education, depressive symptoms, nonmilitary trauma, alcohol use, and prior head injury.

43 ockage site of posterior scleral penetrating trauma, allowed for surgical stabilization and minimal s

44 The acoustic trauma also reduced capillary density and increased depo

45 patients (35.3%) suffered from a low-energy trauma and 11 patients (64.7%) suffered a high-energy tr

46 ia self-report questionnaires after analogue trauma and an intrusion diary completed over 4 days foll

47 activated by noninfectious causes, including trauma and cellular injury, and can have off-target effe

48 ore rigor is needed in tracking sepsis after trauma and evaluating the effectiveness of hospital mand

49 Trauma and mood disorders have been linked to alteration

50 t is well tolerated because it avoids rectal trauma and patients recover immediately.

51 ward prediction error (RPE), are impacted by trauma and predict the future course of affective sympto

52 Trauma and PTSD have been associated with accelerated ce

53 Our findings suggest that lifetime trauma and PTSD may contribute to a higher epigenetic-ba

54 This study evaluated the effect of trauma and PTSD on accelerated GrimAge, an epigenetic pr

55 issociation, after controlling for childhood trauma and PTSD severity.

56 eas: pursuit of higher education, migration, trauma and resilience, and recovery from illness and inj

57 the treatment of mood and anxiety disorders, trauma and stress-related disorders, and substance-relat

58 r risk of developing PTSD after experiencing trauma and/or serve as a mechanism linking PTSD to adver

59 ors (such as cocaine use, weight lifting and trauma) and chronic acquired and/or genetic conditions (

60 logical disorders including ischemic stroke, trauma, and chronic neurodegenerative diseases.

61 ocular disease, history of ocular surgery or trauma, and contact lens wear within 2 weeks of image ac

62 In Taiwan, DM, eye trauma, and dry eye were key predisposing factors for mi

63 re of such experiences (including adversity, trauma, and enrichment) govern their influence on brain

64 including glaucoma, inflammation, ischemia, trauma, and genetic deficits, which are characterized by

65 ly derived and internally validated in burn, trauma, and medical patients at Loyola University Medica

66 hism, may orchestrate sensitivity to stress, trauma, and risk of stress-induced disorders such as PTS

67 ve experiences commonly occur in response to trauma, and while their presence strongly affects treatm

68 Depression and trauma are associated with changes in brain regions impl

69 Cumulative stress and trauma are likely to have lasting impacts on maternal ph

70 The long-term sequelae of trauma are more significant than previously expected.

71 Symptomatic head trauma associated with American-style football (ASF) has

72 tant to understand whether the psychological trauma associated with facial disfigurement alters their

73 he Advancing Understanding of RecOvery afteR traumA (AURORA) Study.

74 1 uncrossmatched red blood cell unit in the trauma bay (2013-2016).

75 Lifetime trauma burden (p = 0.03), current PTSD (p = 0.02) and li

76 D Scale (CAPS) were used to measure lifetime trauma burden and PTSD, respectively.

77 adaptations to severe injury including major trauma, burns, or hemorrhagic shock (HS).

78 Illness severity increased for trauma but fell for nonelective, nontrauma patients (mea

79 herapy for many aortic pathologies including trauma, but stent-grafts stiffen the aorta and likely in

80 ice inflicts mild, moderate, or severe brain trauma by precise compression of the head using a piezoe

81 e symptoms, distinct from PTSD and childhood trauma, can be estimated on the basis of network connect

82 ocedures representing diseases categories in trauma, cancer, congenital anomalies, maternal/reproduct

83 ll TTBI injuries occurred secondary to blunt trauma, caused mainly by accidents (71.2%).

84 m all patients treated for BCVI at a level I trauma center between April 1, 2005, and June 30, 2015,

85 uckerberg San Francisco General Hospital and Trauma Center between April and October 2018.

86 everity Score (ISS) >=10, treated by a Major Trauma Center for the period January 2008 to December 20

87 At least one additional trauma center is needed in 49% of trauma service areas.

88 his score was used to estimate the number of trauma centers allocated to each TSA and compared to the

89 ble-blinded, randomized clinical trial at 20 trauma centers and 39 emergency medical services agencie

90 s following hospitalization in any of the 57 trauma centers in a Canadian trauma system (2013-2016).

91 tor vehicle crash (MVC) treated at 3 level I trauma centers in Boston between 2015 and 2018.

92 erity Score (ISS) >=9] admitted to 3 Level-I trauma centers in Boston were assessed via telephone bet

93 e receiving care in 6 urban academic level-I trauma centers in France between March 2015 and March 20

94 trauma survivors from two level 1 emergency trauma centers, which uses routinely collectible data fr

95 h TSA and compared to the number of existing trauma centers.

96 3 and August 2016 at 2 United States Level-1 trauma centers.

97 trauma) among those admitted to the regional trauma centre and subjected to whole-body computed tomog

98 haft fractures at a university-based level-1 trauma centre were assessed.

99 platforms, four were conducted in specialist trauma clinics, two were delivered in home settings, and

100 ukocyte gene expression can be used in blunt trauma cohorts at 24 hours to distinguish patients who r

101 We developed a murine model of orthopaedic trauma combining tibia fracture and pin fixation with mu

102 Inflammation following joint trauma contributes to cartilage degradation and progress

103 to test perceptual processing of peripheral trauma-cues.

104 brain injury were identified in the National Trauma Database (years 2007-2016).

105 he leading cause of battlefield and civilian trauma deaths.

106 tudy examined associations between childhood trauma, depression, adult cognitive functioning and risk

107 Trauma disproportionately affects the uninsured.

108 Acoustic trauma disrupts cochlear blood flow and damages sensory

109 rfusion during cardiac arrest and mechanical trauma during resuscitation.

110 Thereafter, we compared trauma endophenotypes in FND with regional differences i

111 baseline, the participants reported lifetime trauma events and completed a monetary reward functional

112 luded 218 individuals with current PTSD, 427 trauma-exposed controls without any history of PTSD and

113 y help to distinguish between PTSD cases and trauma-exposed controls.

114 A methylation data from 1,896 PTSD cases and trauma-exposed controls.

115 survivors of interpersonal violence and non-trauma-exposed demographically matched controls underwen

116 oms in a nationally representative sample of trauma-exposed European-American U.S. military veterans

117 ticipants in the initial sample included 840 trauma-exposed individuals recruited as part of the Grad

118 to ELT and PTSD on gray matter structure in trauma-exposed individuals.

119 ry mechanism of intrusive re-experiencing in trauma-exposed individuals.

120 Chronic injection of serum from trauma-exposed males into controls recapitulates metabol

121 Recent trauma-exposed military veterans (n = 46) were grouped i

122 Sleep disturbances are commonly found in trauma-exposed populations.

123 tic influences on MDD stratified by reported trauma exposure (final sample size range: 24,094-92,957)

124 as only significant in individuals reporting trauma exposure (r(g) = 0.24, p = 1.8 x 10(-7) versus r(

125 Both trauma exposure and depression are heritable.

126 When modelling trauma exposure as an environmental influence on depress

127 ssing the proinflammatory immune response to trauma exposure immediately after trauma exposure, in th

128 tudy's purpose was to determine how lifetime trauma exposure influences relationships between reward

129 Trauma exposure is associated with a more severe, persis

130 Evaluating trauma exposure is thus crucial in naturalistic and trea

131 hat sleep therapeutics immediately following trauma exposure may be beneficial and that post-trauma s

132 mportance of examining effects of stress and trauma exposure on neural health in addition to the circ

133 omorbidity and symptomatology, and childhood trauma exposure were assessed.

134 in an emergency department immediately after trauma exposure would predict later chronic development

135 While many individuals recover following trauma exposure, a substantial subset develop adverse po

136 complex relationship exists between reported trauma exposure, body composition, and MDD.

137 -0.05, p = 0.39 in individuals not reporting trauma exposure, difference p = 2.3 x 10(-4)).

138 esponse to trauma exposure immediately after trauma exposure, in the emergency department, may help i

139 Refugees with different trauma exposure, length of time in settlements, and init

140 d offspring characteristics (i.e., childhood trauma exposure, lifetime psychiatric diagnoses, psychot

141 of candidate exosomal miRNAs in response to trauma exposure.

142 order that develops in some people following trauma exposure.

143 orrelation observed between MDD and reported trauma exposure.

144 c review and meta-analysis, we observed that trauma-focused psychological interventions are effective

145 We propose that it could be caused by trauma from air flow from the infusion cannula during th

146 ry for a lower limb fracture caused by major trauma from July 7, 2016, through April 17, 2018, with f

147 ifficult to distinguish the effects of noise trauma from subsequent SNHL on central processes.

148 ctive study, a convolutional neural network (trauma hand radiograph-trained deep learning bone age as

149 A total of 214 trauma hand radiographs from Hasbro Children's Hospital

150 A deep learning model trained on pediatric trauma hand radiographs is on par with automated and man

151 was trained on 15 129 frontal view pediatric trauma hand radiographs obtained between December 14, 20

152 and regression of capillaries after acoustic trauma have long been observed, but the underlying mecha

153 A randomized clinical trial conducted at 24 trauma hospitals representing the UK Major Trauma Networ

154 einaemia, depression, stress, diabetes, head trauma, hypertension in midlife and orthostatic hypotens

155 wing literature highlighting how exposure to trauma, immigration enforcement, changes to social netwo

156 to the long-term impact of symptomatic head trauma in former professional ASF players and other cont

157 wed a significant interaction with childhood trauma in predicting worse symptom severity.

158 Blast trauma, in particular, has come to make up a significant

159 itulates the major manifestations of complex trauma, including nociceptive sensitization, bone fractu

160 ating evidence suggests that sublethal blood trauma-induced by supraphysiological shear exposure-para

161 elop and validate a risk prediction tool for trauma-induced coagulopathy (TIC), to support early ther

162 levels in CSF in humans during inflammatory trauma-induced delirium.

163 Here we use a mouse model of trauma-induced heterotopic ossification (HO) to examine

164 Here we examine, using a mouse model of trauma-induced HO, the local microenvironment of the ini

165 ool nationally shows the need for additional trauma infrastructure across a large segment of the Unit

166 Acute kidney injury (AKI) after major trauma is associated with increased mortality.

167 on in patients with lower-extremity arterial trauma is central to decisions between attempting limb s

168 ) verifying that the endothelial response to trauma is heterogeneous and most likely driven by a gene

169 Trauma is one of the leading causes of death in people u

170 contribution to MDD is greater when reported trauma is present, and that a complex relationship exist

171 Severe trauma is the first cause of disability-adjusted life ye

172 evelopment and their loss, due to disease or trauma, is a leading cause of deafness.

173 Older age, illiterates, previous eye trauma, large family size and family history eye problem

174 NTRK2 methylation was not related to trauma load, suggesting that methylation differences pre

175 ASD, suggesting that the first 2 weeks after trauma may be a uniquely important time period for inter

176 ticipants from 3 months to 3 years after the trauma [median age: 41 years (Q1-Q3 24-54), median injur

177 at and non-combat odors) to assess olfactory trauma memory and emotional response.

178 Importantly, olfactory trauma memory was identified as a mediator of the relati

179 ive re-experiencing of trauma via heightened trauma memory.

180 y, which were both correlated with olfactory trauma memory.

181 onclude that early healing after orthopaedic trauma must be allowed prior to the initiation of exerci

182 4 trauma hospitals representing the UK Major Trauma Network that included 1548 patients aged 16 years

183 respiratory muscle recovery following spinal trauma occurs through oxygen transport, metabolic demand

184 s and the impact of anesthesia and emotional trauma of nonsedated office probings on patients and may

185 led in Drosophila using devices that inflict trauma on multiple parts of the fly body, including the

186 storing brain function in the event of brain trauma or disease.

187 ruction of large bone defects resulting from trauma or diseases, donor site morbidity and limited ava

188 in the jaws can occur due to periodontitis, trauma or following tumor resection.

189 e inflammatory response, derived from tissue trauma or neurodegenerative diseases such as Alzheimer's

190 IOL dislocation are associated with surgical trauma or preexisting zonulopathy.

191 ular surface diseases, intraocular diseases, trauma or surgery were exclusion criterias.

192 ulation of interest was neonatal, pediatric, trauma, or noncritically ill.

193 rare complication of esophageal malignancy, trauma, or surgery.

194 Analyze the impact of the ACA on trauma outcomes at a population level and within at-risk

195 compared with control spleens resected after trauma (P < 0.001).

196 -10 concentrations decreased with time after trauma (p = 0.001-0.04).

197 Over 30 months, major trauma patients [Injury Severity Score (ISS) >=9] admitt

198 A retrospective review of all trauma patients admitted to the SICU before and after im

199 e called for a mechanism to routinely follow trauma patients and determine factors associated with su

200 We have studied more than 2750 trauma patients and identified that patients with high c

201 Severely burned and non-burned trauma patients are at risk for acute kidney injury (AKI

202 Trauma patients are too often qualified for WBCT.

203 ertension were identified in the orthopaedic trauma patients as potential risks for the development o

204 Identifying those trauma patients early would improve treatment plans and

205 Trauma patients had a lower hospital mortality than none

206 ecent clinical study showed that human brain trauma patients had enhanced expression of type-1 IFN; s

207 Trauma patients have become less likely to be discharged

208 The age and illness severity of adult ICU trauma patients in Australia and New Zealand has increas

209 Although younger trauma patients may adapt to these effects, these change

210 White adult trauma patients requiring more than 2 days of mechanical

211 Trauma patients were younger (49.0 +/- 21.6 vs 60.6 +/-

212 dehydroascorbate, fumarate, and succinate in trauma patients who developed ARDS (p<0.05).

213 a interleukin-6 for prospectively predicting trauma patients who require intensive care unit stays lo

214 is is a prospective study of 237 orthopaedic trauma patients who were consecutively scheduled for ope

215 Vehicle-trauma patients who were suffered from vehicle accidents

216 f hypoalbuminemia and obesity in orthopaedic trauma patients with high-energy injuries and to investi

217 ypoalbuminemia and obesity among orthopaedic trauma patients with high-energy injuries.

218 raumatic tracheobronchial injuries (TTBI) in trauma patients with multiple injuries derived from the

219 REBOA can be used in blunt and penetrating trauma patients, including those in arrest.

220 mes (KDIGO) criteria for burn and non-burned trauma patients.

221 ng cause of potentially preventable death in trauma patients.

222 h surgical site complications in orthopaedic trauma patients.

223 nowledge gap on end-of-life resource use for trauma patients.

224 iation exposure experienced by the pediatric trauma patients; second, model the level of risk of deve

225 Compared to patients with low-energy trauma, patients suffering from high-energy trauma showe

226 ts meeting the criteria of a severe multiple trauma (polytrauma) among those admitted to the regional

227 strategy may have overlooked certain complex-trauma populations with severe and enduring mental healt

228 The trauma PPPDR was almost double that estimated by the Nat

229 National Academies of Sciences estimated the trauma preventable death rate in the United States to be

230 There is growing evidence that exposure to trauma prior to conception can affect offspring.

231 newly exchanged catheter.The patient denied trauma prior to the swelling.

232 Combined hybrid trauma procedures occurred in 18% of cases (surgery (82%

233 d individuals recruited as part of the Grady Trauma Project.

234 eat and may be disrupted in anxiety and post-trauma psychopathology.

235 The Pediatric Trauma Quality Improvement Program (2017) was queried fo

236 I and II North American Centers enrolled in Trauma Quality Improvement Program from 2010 to 2017.

237 (IT) within the American College of Surgeons Trauma Quality Improvement Program.

238 After trauma, regeneration of adult CNS axons is abortive, cau

239 The US and UK Combat Trauma Registries were scrutinised for patients with HI

240 Due to limitations of trauma registries, we have an incomplete understanding o

241 trauma system (n = 508) and UK Joint Theatre Trauma Registry (n = 51) populations respectively.

242 validated on data from the UK Joint Theatre Trauma Registry.

243 aged conservatively, as it was attributed to trauma related-impact area.

244 t treating the amnesia by re-exposure to all trauma-related cues cures PTSD-like hypermnesia.

245 memory function, were down-regulated in head trauma-related disorders.

246 form prevention and treatment of stress- and trauma-related disorders.

247 ations for understanding the neural basis of trauma-related disorders.

248 utic target for individuals with stress- and trauma-related disorders.SIGNIFICANCE STATEMENT Patients

249 he authors tested for continuous measures of trauma-related dissociation using the Multidimensional I

250 Trauma-related dissociative symptoms, distinct from PTSD

251 ticipants, examined associations of parental trauma-related variables (i.e., sex of the exposed paren

252 few studies have investigated brain network-trauma relationships in this population.

253 osed to radiation in the context of multiple traumas remains unclear.

254 Delayed exercise after complex orthopaedic trauma results in decreased muscle fibrosis and improved

255 Trauma resuscitations are complex critical care events t

256 am leadership and patient care during actual trauma resuscitations.

257 essive or impulsive traits explain childhood trauma's effects on SI variability and whether those wit

258 sing and activate sensory representations of trauma, sensory disinhibition can constitute a sensory m

259 additional trauma center is needed in 49% of trauma service areas.

260 trauma, patients suffering from high-energy trauma showed significantly lower scores in "daily activ

261 uma exposure may be beneficial and that post-trauma sleep needs to be further examined in the context

262 nal cohort study was performed involving 127 trauma subjects.

263 After CNS trauma such as spinal cord injury, the ability of surviv

264 In the context of major trauma such as surgery, concerns have been raised regard

265 The field of trauma surgery established regionalized systems of care

266 ive of the Equity, Quality, and Inclusion in Trauma Surgery Practice Ad Hoc Task Force of the Eastern

267 We randomly selected severe trauma survivors (abbreviated injury score >=3 in at lea

268 ic sequelae (APNS) are common among civilian trauma survivors and military veterans.

269 Offspring of trauma survivors are more likely to develop PTSD, mood,

270 dependently collected prospective cohorts of trauma survivors from two level 1 emergency trauma cente

271 valence is needed to determine the burden of trauma symptoms and PTSD in SSA and to identify acceptab

272 rm contribute to the inheritance of specific trauma symptoms.

273 n any of the 57 trauma centers in a Canadian trauma system (2013-2016).

274 tissue were 12.2% and 19.6% in the US joint trauma system (n = 508) and UK Joint Theatre Trauma Regi

275 MTF to ascertain if differences in deployed trauma systems affected outcomes.

276 Robust trauma systems have improved outcomes for severely injur

277 cussion around investing in the expansion of trauma systems nationally, however in many instances lac

278 strategies to improve quality of care across trauma systems will remain difficult.

279 cope of indications and rules of conduct for trauma teams.

280 Test the hypothesis that trauma TEVAR is associated with LV mass increase and adv

281 equent cases of hospitalized musculoskeletal trauma, the inflammatory responses and cell population d

282 d, directly and interactively with childhood trauma, to the clinical and circuit-level phenotypes of

283 contributed to intrusive re-experiencing of trauma via heightened trauma memory.

284 Childhood trauma was associated with depression and reduced hippoc

285 Childhood trauma was associated with lower hippocampal volume howe

286 Symptomatic head trauma was not correlated with average stride times in e

287 Trauma was the cause in 8 (72%) cases.

288 f the Eastern Association for the Surgery of Trauma was to characterize equity and inclusion in ACS.

289 ts with a thoracic aortic IT following blunt trauma were captured from Level I and II North American

290 inflammation-related organ failures, and CNS trauma were the most common pathophysiologies leading to

291 Psychological traumas were key exciting causes, but so were somatic di

292 sical and sexual abuse, as well as emotional trauma, which projected onto gray matter volume patterns

293 ients with primary CH without any history of trauma who attended the headache clinic during the same

294 t little data are available in patients with trauma who develop sepsis.

295 We compared 77,002 trauma with 741,829 nonelective, nontrauma patients.

296 Treating serious bone trauma with an osteo-inductive agent such as bone morpho

297 reatment of physical injuries resulting from trauma with opioids, the ability of opioid treatments to

298 er surgery is an exemplar of major operative trauma, with well-defined risks of respiratory, cardiac,

299 or scleral perforation in a severe ballistic trauma without previous instrumental signs of penetratin

300 pothesized that ASF-related symptomatic head trauma would predict worse gait performance, particularl