ライフサイエンスコーパス: trichloro

1 furanosyl) benzimidazole (1263W94) and 2,5,6-trichloro-1(beta-D-ribofuranosyl)benzimidazole (TCRB) we

2 Chlorofluorocarbons including 1,1,2-trichloro-1,2,2-trifluoroethane (CFC-113) often occur in

3 of 2,4,6-triamino-1,3,5-triazine with 2,4,6-trichloro-1,3,5-triazine at 1.0-1.5 GPa and 500-550 degr

4 was observed when 2,4,6-trifluoro- or 2,4,6-trichloro-1,3,5-triazine were used--1,3,5-triazines that

5 eloped an efficient cyanuric chloride (2,4,6-trichloro-1,3,5-triazine, TCT) catalyzed approach for th

6 none (OH-DCMBQ) from DCMBQ, 5-hydroxyl-2,3,6-trichloro-1,4-benzoquinone (OH-TCBQ) from TCBQ, and 3-hy

7 2,6-dichloro-1,4-benzoquinone (DCBQ), 2,3,6-trichloro-1,4-benzoquinone (TCBQ), 2,6-dichloro-3-methyl

8 2,6-dichloro-1,4-benzoquinone (DCBQ), 2,3,6-trichloro-1,4-benzoquinone (TCBQ), 2,6-dichloro-3-methyl

9 oro-3-methyl-1,4-benzoquinone (DCMBQ), 2,3,6-trichloro-1,4-benzoquinone (TCBQ), and 2,6-dibromobenzoq

10 furanose to give, after deprotection, 2,5, 6-trichloro-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)be

11 e resulting low overall yield (5%) of 2,5, 6-trichloro-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)be

12 ed with DAST and deprotected to yield 2,5, 6-trichloro-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)be

13 fluorinated benzimidazole nucleosides 2,5, 6-trichloro-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)be

14 In addition, 3-acetyl-2,5,6-trichloro-1-(2-deoxy-beta-d-ribofuranosyl)indole was als

15 -D-arabinofuranosyl)benzimidazole and 2,5, 6-trichloro-1-(3-deoxy-3-fluoro-beta-D-xylofuranosyl)benzi

16 ta-D-arabinofuranosyl)benzimidazole , 2,5, 6-trichloro-1-(3-deoxy-3-fluoro-beta-D-xylofuranosyl)benzi

17 ing compounds [e.g., CMP1 (4-methyl-N-[2,2,2-trichloro-1-(4-nitro-phenylsulfanyl)-ethyl]-benzamide)]

18 The D-nucleosides 2,5, 6-trichloro-1-(beta-D-erythrofuranosyl)benzimidazole (8a)

19 for the corresponding ribofuranosides 2,5, 6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole (4a), it

20 esized as ring-contracted analogues of 2,5,6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole (TCRB) a

21 nd the fact that 5'-deoxy analogues of 2,5,6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole (TCRB) a

22 2,5,6-Trichloro-1-(beta-d-ribofuranosyl)benzimidazole (TCRB) a

23 2,5,6-Trichloro-1-(beta-d-ribofuranosyl)benzimidazole (TCRB) a

24 2,5,6-Trichloro-1-(beta-D-ribofuranosyl)benzimidazole (TCRB) a

25 halogenated benzimidazole nucleosides 2,5, 6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole (TCRB) a

26 ity in vivo of the glycosidic bond of 2,5, 6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole (TCRB) p

27 y, 5'-ethoxy, and 5'-butoxy analogs of 2,5,6-trichloro-1-(beta-D-ribofuranosyl)benzimidazole (TCRB) w

28 bofuranosyl)indole (FTCRI) and 3-cyano-2,5,6-trichloro-1-(beta-D-ribofuranosyl)indole (CTCRI) were sy

29 y derivatives of the reported 3-formyl-2,5,6-trichloro-1-(beta-D-ribofuranosyl)indole (FTCRI) and 3-c

30 The previously reported 3-formyl-2,5,6-trichloro-1-(beta-D-ribofuranosyl)indole (FTCRI) and its

31 difications of the previously reported 2,5,6-trichloro-1-(beta-d-ribofuranosyl)indole at the 3-positi

32 ents at the 3-position (e.g., 3-methyl-2,5,6-trichloro-1-(beta-D-ribofuranosyl)indole) were much less

33 re active against HCMV (e.g., 3-formyl-2,5,6-trichloro-1-(beta-D-ribofuranosyl)indole, FTCRI, IC50 =

34 The analogue 2,5,6-trichloro-1-(beta-D-ribofuranosyl)indole-3-carboxamide o

35 yethoxy)methyl]benzimidazole (11a) and 2,5,6-trichloro-1-[(1,3-dihydroxy-2-propoxy)methyl] benzimidaz

36 d 19a, which on debenzylation afforded 2,5,6-trichloro-1-[(2-hydroxyethoxy)methyl]benzimidazole (11a)

37 2,5,6-Trichloro-1-beta-D-ribofuranosyl benzimidazole (TCRB) is

38 was followed by deprotection to afford 2,4,5-trichloro-1-beta-D-ribofuranosylbenzimidazole (20a), and

39 eprotection afforded the corresponding 2,4,6-trichloro-1-beta-D-ribofuranosylbenzimidazole (7a) and 2

40 osyl benzimidazole riboside) and TCRB (2,5,6-trichloro-1-beta-D-riborfuranosyl benzimidazole riboside

41 el lentiviral shRNAs or blocker 1-[4-[(2,3,3-trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoro

42 We also identified 2,3,6-trichloro-(1,4)benzoquinone (TriCBQ), 2,3-dibromo-5,6-di

43 2,5, 6-Trichloro-(1-beta-D-ribofuranosyl)indole (19) was prepar

44 te glass coverslips were functionalized with trichloro(1H,1H,2H,2H-perfluorooctyl)silane on one side,

45 of the antimicrobial triclosan (TCS; 2,4,4'-trichloro-2'-hydroxydiphenyl ether) was developed.

46 4-metoxybenzophenone); and triclosan (2,4,4'-trichloro-2'-hydroxyphenyl ether).

47 agricultural use of the organochlorine 1,1,1-trichloro-2,2'bis(p-chlorophenyl)ethane (DDT) and increa

48 henyls (PBBs), hexabromobenzene (HBB), 1,1,1-trichloro-2,2-bis(4-chlorophenyl) ethane (DDT), and tris

49 DDT (1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane), a contact inse

50 the ubiquitous global contaminant DDT (1,1,1-trichloro-2,2-bis(p-chlorophenyl) ethane), have since de

51 specific for the insecticidal p.p'DDT [1,1,1-trichloro-2,2-bis(p-chlorophenyl) ethane].

52 e authors explored whether exposure to 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) and its is

53 1,1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) and its me

54 The insecticide 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) is still u

55 evious studies of pregnancy losses and 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) were limit

56 , the main metabolite of the pesticide 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT), are hormo

57 1,1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane (DDT), the first

58 nant, is a metabolite of the pesticide 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT).

59 The primary 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane metabolite, p,p'

60 DDT (1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane) is highly effec

61 levels of plasma DDE (a metabolite of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane), numbers and ty

62 traction was used to extract 4,4'-DDT [1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane] and its metabol

63 gstD1 encodes a 1,1,1-trichloro-2,2-bis-(P-chlorophenyl)ethane dehydrochlorina

64 1,1-trichloro-2,2-di(4-chlorophenyl)ethane (DDT) and its met

65 rine from chloropentafluorobenzene and 1,3,5-trichloro-2,4,6-trifluorobenzene.

66 range from 3.75 +/- 0.04 kJ mol(-1) in 1,3,5-trichloro-2,4,6-trifluorobenzene.TMP to 7.08 +/- 0.15 kJ

67 lotrinitrobenzene explosives: 1:1 DADP/1,3,5-trichloro-2,4,6-trinitrobenzene (TCTNB), 1:1 DADP/1,3,5-

68 o alpha-aryloxyisobutyric acid 2 using 1,1,1-trichloro-2-methyl-2-propanol (chloretone) was developed

69 richloromethane, dichloroacetonitrile, 1,1,1-trichloro-2-propanone, 2,2,2-trichloroethanol, benzonitr

70 trations of pyrethroid metabolites and 3,5,6-trichloro-2-pyridinol (TCPy) in samples collected in 200

71 henone, perfluoroheptanesulfonic acid, 3,5,6-trichloro-2-pyridinol, and 2,4,5-trichlorophenoxyacetic

72 determine chlorpyrifos (O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphorothioate) (CP) in tomato by

73 2,4,5-Trichloro-, 2-bromo-4,5-dichloro-, and 2,4,5-tribromoimi

74 l]): 2,2,2-tribromo-(267% [240-294]) > 2,2,2-trichloro-(215% [196-234]) > chloral hydrate (165% [161-

75 ch include 2,5-dichloro, 3,4-dichloro, 3,4,5-trichloro, 3-methoxy, and 2,5-dimethoxy analogues 13-17

76 ive 80-90% yields of 2,6-dichloro- and 2,6,7-trichloro-3-(2,3-dideoxy-2,3-didehydro-d/l-erythrofurano

77 HSV-1 activity, the alpha-d anomer of 2,6,7-trichloro-3-(erythrofuranosyl)imidazo[1,2-a]pyridine pro

78 m TriCHQ-2 and subsequent formation of 3,5,6-trichloro-4-hydroxycyclohexa-2,4-dienone (TriCHQ*).

79 e also produces substantial amounts of 2,3,5-trichloro-6-S-glutathionylhydroquinone (GS-TriCHQ) and a

80 First, the product of such a reaction, 2,3,5-trichloro-6-S-glutathionylhydroquinone, is not a kinetic

81 ess toxic surrogate standard for TCDD [2,3,7-trichloro-8-methyl-dibenzo-p-dioxin (TMDD; XVII)] which

82 Moreover, the trichloro acetimidamide directing group was found to be

83 The readily synthesized trichloro acetimidamide was found to be an excellent dir

84 Similar to the previously reported 2,5,6-trichloro analog (TCRB), the 5,6-dibromo ribonucleoside

85 The 4',7,8-trichloro analogue (38) of mazindol was the most potent

86 erpes simplex virus type 1 revealed that the trichloro analogues of TCRB (2a, 3a) were nearly as acti

87 onality of intermediate reactivity (chloro-, trichloro-, and trifluoroethyl esters), allowed quinone

88 .g., 4,4'-dichloro-biphenyl-2,5-diol, 3,6,4'-trichloro-biphenyl-2,5-diol, 3,4,6,-trichloro-biphenyl-2

89 , 3,6,4'-trichloro-biphenyl-2,5-diol, 3,4,6,-trichloro-biphenyl-2,5-diol, and their corresponding qui

90 Treatment with BF3.Et2O gives a 3,5,8-trichloro-BODIPY that readily undergoes regioselective S

91 respectively, and 0.68 ng mL(-1) (n = 1) for trichloro-BPA.

92 ynthesized and converted to its trinitro and trichloro derivatives (see scheme; R=NO(2), Cl).

93 immunomodulating tellurium compound ammonium trichloro (dioxoethylene-o,o') tellurate (AS101) on dext

94 Second, AS101 [ammonium trichloro(dioxoethylene-o,o')tellurate], a compound that

95 Among the HNQs tested, 5,6,7-trichloro HNQ (8i) was the most potent antagonist with a

96 2,4,6-Trichlorophenol (2) and 2,4,6-trichloro-m-cresol (5) react with calcium hypochlorite (

97 ydrophobic agents, ethyl 2-cyanoacrylate and trichloro(octadecyl)silane were applied by a simple dip-

98 yzes the GSH-dependent conversion of TeCH to trichloro-p-hydroquinone (TriCH) and then to dichloro-p-

99 Since GS-trichloro-p-hydroquinone is uncommon in nature, the exte

100 glutathione (GSH)-dependent reduction of GS-trichloro-p-hydroquinone to trichloro-p-hydroquinone.

101 reduction of GS-trichloro-p-hydroquinone to trichloro-p-hydroquinone.

102 increased risk associated with use of 2,4,5-trichloro-phenoxypropionic acid (2,4,5-TP) and possibly

103 asal medium in the presence of 4-amino-3,5,6,trichloro-picolinic acid (picloram) inducing the formati

104 5,6,7-Trichloro-QTO also had a Kb of 180 nM for AMPA receptors

105 Among the derivatives evaluated, 5,6,7-trichloro-QTO was the most potent antagonist with an IC5

106 moderately strong acids in aqueous solution (trichloro-, trifluoro-, chlorodifluoro-, and dichloroace