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1 , and extractable small molecules (primarily triterpenoids).
2 eroidal, while those of the sea cucumber are triterpenoid.
3 the X-ray crystal structure of a fluorinated triterpenoid.
4 programs toward the production of bioactive triterpenoids.
5 train that no longer produced any polycyclic triterpenoids.
6 or the backbone structures of the major cork triterpenoids.
7 sinosteroid phytohormones, and non-steroidal triterpenoids.
8 tive promise of targeting Nrf2 pathways with triterpenoids.
9 entive and chemotherapeutic potential of the triterpenoids.
10 iminate promoter activity in response to the triterpenoids.
11 AP mediated by the presence of phenolics and triterpenoids.
12 vity (IC(50) = 0.07 microM) in this group of triterpenoids.
13 quassinoid, apoprotolimonoid, and glabretane triterpenoids.
14 ids (phenethylamines derived betalains), and triterpenoids.
15 challenging and hitherto inaccessible marine triterpenoids.
16 ifications for the biosynthesis of bioactive triterpenoids.
17 pation in the biosynthesis of fruit-specific triterpenoids.
18 or sustainable production of bioactive plant triterpenoids.
19 eading to the synthesis of highly oxygenated triterpenoids.
29 the ethyl amide derivative of the synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oi
32 e found that administration of the synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9(11)-dien-C28-m
35 f apoptosis induction by the novel synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic ac
38 f collagenase gene expression, the synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic ac
41 on the basis of the structure of a synthetic triterpenoid, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-o
43 ave studied the effects of two new synthetic triterpenoids, 2-cyano-3,12-dioxooleana-1,9-dien-28-oic
45 nolic acids, 9 flavonols, 7 flavan-3-ols), 3 triterpenoids, 7 carotenoids, 5 chlorophylls and 4 tocop
46 ficant drought-induced accumulation, whereas triterpenoid abundance remained predominantly unchanged.
47 y maintained in sorghum; and 3) sorghum leaf triterpenoids accumulate in a spatial pattern that was p
52 thase-like enzyme can not only glucuronidate triterpenoid aglycones but also alter the product profil
55 resulted in the identification of the lupane triterpenoid alphitolic acid as the main antibiofilm met
66 ults shed light on the biosynthesis of olive triterpenoids and provide new gene targets for germplasm
67 test compounds, the level of major bioactive triterpenoids and related metabolites were measured usin
68 t enhancement of Smad signaling by synthetic triterpenoids and should further their optimal use for a
69 were matched with saponin glycosides, while triterpenoids and steroids occurred in the inactive extr
70 reversible nature of the interaction between triterpenoids and thiols has hindered attempts to identi
71 uction of two classes of defenses, saponins (triterpenoids) and flavans (phenolics), in Pentaclethra
72 n E, certain simple phenolics, phytosterols, triterpenoids, and anthocyanins one day earlier than the
73 olymerized compounds, hydroxycinnamic acids, triterpenoids, and tetraterpenids, as well as exhibited
87 , but new and more potent ligands, including triterpenoids, are being investigated as therapeutic age
89 mly synthesized about 60 oleanane and ursane triterpenoids as potential anti-inflammatory and cancer
92 Oats (Avena spp) synthesize antimicrobial triterpenoids (avenacins) that provide protection agains
93 report that Nrf2 activation by the synthetic triterpenoids, bardoxolone methyl (BARD) and 2-cyano-3,1
95 lpropanoid biosynthesis, sesquiterpenoid and triterpenoid biosynthesis for protective cuticle and wax
97 eads to the formation and duplication of two triterpenoid biosynthesis-related gene clusters (BGCs).
104 red these phenotypes and further showed that triterpenoid biosynthetic and glucosinolate catabolic ge
105 mple, only the Ziziphoid clade developed the triterpenoid biosynthetic pathway, whereas the Rhamnoid
107 ersity-oriented strategy, whereby the parent triterpenoids bryonolic acid and lanosterol are converte
108 n pathways and demonstrate this approach for triterpenoids by functionally characterizing three cytoc
111 qual or greater potency than the pentacyclic triterpenoid CDDO in inflammation and carcinogenesis rel
112 It has been shown that the novel synthetic triterpenoid CDDO inhibits proliferation and induces dif
116 ous work, we demonstrated that the synthetic triterpenoid CDDO-methyl ester (CDDO-Me) converts breast
120 R3-CXCL11 axis and elucidate the role of the triterpenoid CF(3)DODA-Me in abrogating several of these
121 g body for converting lanostane to ergostane triterpenoids, coenzymes Q (COQ) for antroquinonol biosy
122 s study, the antiproliferative effect of the triterpenoid compound cucurbitacin B was tested in vitro
123 n be terminated by glycyrrhizic acid (GA), a triterpenoid compound earlier shown to inhibit the lytic
131 esting that the structure of the side chain, triterpenoid core, and oligosaccharide domain together o
136 mically characterized a novel, semisynthetic triterpenoid derivative, 3-cinnamoyl-11-keto-beta-boswel
138 In the present study, we have focused on triterpenoid derivatives, which have been shown to induc
140 tes introgression line population, we mapped triterpenoid differences to a genomic region that includ
141 tor antagonist RU-486, indicating that these triterpenoids do not act through the glucocorticoid rece
142 sis of phainanoid A, a unique dammarane-type triterpenoid (DTT), using an unusual bidirectional synth
143 rationale for pharmaceutical development of triterpenoid dual-function proteosome/NF-kappaB inhibito
144 tial arrangement of functional groups in the triterpenoid E-ring, driving to different taste sensatio
145 le structure is more potent than pentacyclic triterpenoids (e.g., CDDO and bardoxolone methyl) and tr
146 of therapeutics, with synthetic tetracyclic triterpenoids (e.g., steroids) being the most well repre
147 nt and the biosynthesis of sesquiterpenoids, triterpenoids, ergostanes, antroquinonol, and antrocamph
148 and dinitrile derivatives are novel oleanane triterpenoids exhibiting promise as both therapeutic and
149 ting the potential of small molecules of the triterpenoid family as effective agents for the chemopre
150 sfully afforded the single isomer, 16beta-ol triterpenoid, followed by configuration inversion to the
151 ality, and mass: ursolic acid (a pentacyclic triterpenoid found in apples) and tomatidine (a steroida
152 e effect of ursolic acid (UA), a pentacyclic triterpenoid found in rosemary and holy basil, on apopto
153 ous ursanic, oleanic and lupanic pentacyclic triterpenoids found in apple peel were studied for anti-
155 t the identification of escin, a pentacyclic triterpenoid from horse chestnut that exhibits antitumor
158 Ibrexafungerp, a novel, first-in-class oral triterpenoid glucan synthase inhibitor, has demonstrated
159 y here the biosynthetic pathway of the sweet triterpenoid glycoside mogroside V, which has a sweeteni
160 ated fraction, two analogous Lyonia-specific triterpenoid glycosides were characterized as ovipositio
161 to investigate the chemical requirements of triterpenoid glycosides within a new binding pocket to c
163 synthetic analog of the naturally occurring triterpenoid glycyrrhetinic acid, which contains a 2-cya
165 onol glycosides, betalains and some uncommon triterpenoids have been related to the improvement of hu
167 telletin E, highly cytotoxic isomalabaricane triterpenoids, have been accomplished in a linear sequen
168 put screening, we identified the pentacyclic triterpenoid hederagenin (1) as a novel selective antago
170 nolides, a highly diverse group of steroidal triterpenoids important in plant defense and amenable to
172 ese previous findings suggest a key role for triterpenoids in cork material quality, directly testing
174 eal a process for skeletal rearrangements of triterpenoids in nature that expands their scaffold dive
177 ations of flavonoids, spatholosineside A and triterpenoids in the oven-dried samples compared with th
179 PAHs), along with diagnostic conifer-derived triterpenoids in two hearth-like archaeological structur
188 (a) suggest a novel mechanism of action for triterpenoid-induced cell death; (b) are among the first
189 of the 6-6-6-5 tetracyclic lanosterol (a key triterpenoid intermediate in the biosynthesis of cholest
190 s, which makes the biosynthesis of this seco-triterpenoid intriguing from an evolutionary standpoint.
191 emonstrate that Nrf2 activation by synthetic triterpenoids is a promising candidate target to protect
192 biosynthesis of the majority of sorghum leaf triterpenoids is mediated by a gene that maize and sorgh
195 Acetyl-keto-beta-boswellic acid (AKBA), a triterpenoid isolated from Boswellia carterri Birdw and
203 identified including 43 ellagitannins and 16 triterpenoids, mainly oleane derivatives and glycosylate
204 erved that Bcl-X(L) overexpression inhibited triterpenoid-mediated killing of prostate cancer cell li
206 and neuroprotective effects, associated with triterpenoid metabolites, while PLE extract showed anti-
212 ynthetic precursor to a variety of oxacyclic triterpenoid natural products, has been efficiently synt
215 tabolomic changes generated by the bioactive triterpenoids of Centell-S alone, and in combination wit
219 ed yeasts and report ten hitherto unreported triterpenoid oxidation activities, including a cyclizati
224 olar extractables from cork were pentacyclic triterpenoids, primarily betulinic acid, friedelin, and
225 er steroid-like molecules, such as the plant triterpenoids pristimerin and lupeol, affect sperm ferti
228 mplete characterization of ellagitannins and triterpenoids profiles by HPLC-DAD-MS and (1)H NMR and a
229 linkage between the tetrasaccharide and the triterpenoid quillaic acid (QA) core or within the tetra
230 d in border cells, while many flavonoid- and triterpenoid-related metabolite and transcript levels we
232 activation of the human HO-1 promoter by the triterpenoids requires an antioxidant response element (
235 Escin is a mixture of over 30 glycosylated triterpenoid (saponin) structures, extracted from the dr
236 e compounds, such as aescin, barrigenol-type triterpenoid saponins (BAT), and aesculin, a glycosylate
237 isolation and partial purification of novel triterpenoid saponins [Fraction 35 (F035)] and two pure
238 oliferation of HeLa cancer cells were mainly triterpenoid saponins accompanied by phenolic acids.
242 o control the production of anti-nutritional triterpenoid saponins found in quinoa seeds, including a
243 bition of nuclear factor kappaB suggest that triterpenoid saponins from A. victoriae have potential a
245 avicin G, a family of natural plant-derived triterpenoid saponins from Acacia victoriae, mislocalize
246 e tested the ability of avicins, a family of triterpenoid saponins obtained from Acacia victoriae (Be
247 growth inhibitory properties of a mixture of triterpenoid saponins obtained from an Australian desert
248 orted the extraction of avicins, a family of triterpenoid saponins obtained from the Australian deser
249 containing large quantities of oleanane-type triterpenoid saponins with anticancer properties and str
250 similar molar absorptivity for steroidal and triterpenoid saponins with high specificity in complex m
251 unds (saponins), of which the oleanane-based triterpenoid saponins, saponariosides A and B, are the m
257 findings suggest CDDO and related synthetic triterpenoids should be further evaluated as potential n
258 enoids, diterpenoids, quassinoids, steroids, triterpenoids, simple and complex phenolics, and several
260 econdary metabolites comprising glycosylated triterpenoids, steroids or steroidal alkaloids with a br
261 ith high percentages of alicyclic compounds (triterpenoids, steroids, or tocopherols) largely restric
262 ential of CYP716s as a source for generating triterpenoid structural diversity and expand the toolbox
263 olic acid, a naturally occurring pentacyclic triterpenoid, successfully inhibited binding of Abeta to
265 main active ingredients are diterpenoids and triterpenoids, such as triptolide and celastrol, respect
266 by electrophoretic mobility shift assay, the triterpenoid suppressed nuclear factor-kappaB (NF-kappaB
268 To predict functions and specificity of triterpenoid synthases, a mechanism-based, multi-interme
269 nthesis of mogroside V: squalene epoxidases, triterpenoid synthases, epoxide hydrolases, cytochrome P
271 t provides valuable mechanistic insight into triterpenoid synthesis and reveals diagnostic amino acid
272 t transition, sorghum leaf waxes are rich in triterpenoids that are absent from maize; 2) biosynthesi
273 t the C-3 position are a subset of bacterial triterpenoids that are readily preserved in modern and a
274 bitanes are a family of structurally complex triterpenoids that characteristically contain three ster
278 We report the first use of new synthetic triterpenoids to prevent lung cancer in experimental ani
279 ing indicated a differential localization of triterpenoids to the periderm and sesquiterpene alkaloid
280 was to determine whether derivatives of the triterpenoid (TP) 2-cyano-3,12-dioxooleana-1,9-dien-28-o
286 vonoids, proanthocyanidin B2, phenolics, and triterpenoids were annotated as the major classes of sec
288 re involved in steric discrimination between triterpenoids, whereas the position and identity of the
289 OA is an attractive, dietary nontoxic plant triterpenoid, which suppresses the production of proinfl
290 the precursor of all known angiosperm cyclic triterpenoids, which include membrane sterols, brassinos
291 ilberry and lingonberry cuticular waxes were triterpenoids, while fatty acids and alkanes were the do
294 ture of B-15, 19 novel olean- and urs-12-ene triterpenoids with a 1-en-3-one functionality having a s
295 (OA) and maslinic (MA) acids are two natural triterpenoids with a wide range of beneficial effects fo
296 of iNOS and COX-2 expression) of a series of triterpenoids with Michael reaction centers were closely
297 phainanoids, a novel class of dammarane-type triterpenoids with potent immunosuppressive activities a
298 synthesized 16 new olean- and urs-1-en-3-one triterpenoids with various modified rings C as potential