ライフサイエンスコーパス: trophectoderm

1 al adhesion by PKC can regulate migration of trophectoderm.

2 the inner cell mass, primitive endoderm and trophectoderm.

3 rise to cells of the inner cell mass and the trophectoderm.

4 uence development and differentiation of the trophectoderm.

5 surrounded by an extra-embryonic layer, the trophectoderm.

6 nd could potentially transduce the conceptus trophectoderm.

7 into viral particles and transmitted to the trophectoderm.

8 the determination of the inner cell mass and trophectoderm.

9 g the development of endoderm, mesoderm, and trophectoderm.

10 to embryonic tissues but not extraembryonic trophectoderm.

11 educed potential that contribute more to the trophectoderm.

12 Cs and acquire features of post-implantation trophectoderm.

13 , that this lagging cell is the precursor of trophectoderm.

14 envelope protein production in the conceptus trophectoderm.

15 ressed only in the inner cell mass and polar trophectoderm.

16 the oocyte and embryo defines the lineage to trophectoderm.

17 ing the blastocyst cavity and its associated trophectoderm.

18 cleavage cycle tends to contribute to mural trophectoderm.

19 ration of extraembryonic ectoderm from polar trophectoderm.

20 ere also detected in binucleate cells of the trophectoderm.

21 st and the first extra-embryonic tissue, the trophectoderm.

22 ng and forming both an inner cell mass and a trophectoderm.

23 cysts, coincident with the appearance of the trophectoderm.

24 oss of pluripotency and dedifferentiation to trophectoderm.

25 he uterine luminal epithelium and blastocyst trophectoderm.

26 tropin (hCG) is first expressed in embryonic trophectoderm.

27 iation to extraembryonic endoderm (ExEn) and trophectoderm.

28 , establishing the inner cell mass (ICM) and trophectoderm.

29 he human blastocyst are also able to produce trophectoderm.

30 ls are restricted accordingly from producing trophectoderm.

31 onic inner cell mass and the extra-embryonic trophectoderm.

32 rimate embryos resulted in a failure to form trophectoderm.

33 ocyst, producing the inner cell mass and the trophectoderm.

34 e transporter SLC7A1 mRNA in ovine conceptus trophectoderm.

35 , mediating preferential localization to the trophectoderm.

36 ripotent inner cell mass and differentiating trophectoderm.

37 n of the pluripotent inner cell mass and the trophectoderm, a process regulated by cell polarity prot

38 ement that drives reporter expression in the trophectoderm, a subset of cells in the extraembryonic r

39 ts, MOEP19 localized in both mural and polar trophectoderm and a subset of embryos showed inner cell

40 lian embryos sequentially differentiate into trophectoderm and an inner cell mass, the latter of whic

41 pressed at high levels on the surface of the trophectoderm and anandamide (N-arachi-donoylethanolamin

42 ndular epithelia as well as in the conceptus trophectoderm and are essential for conceptus elongation

43 embryonic stem cells readily make blastocyst trophectoderm and descendant trophoblast cell types.

44 to rodents, the mechanisms underlying human trophectoderm and early placenta specification are under

45 last is synergistically enhanced by limiting trophectoderm and epiblast fates.

46 to remove Cited2 from overlapping subsets of trophectoderm and extra-embryonic mesoderm.

47 ncreased differentiation of cells toward the trophectoderm and hypoblast lineages compared with that

48 cells can differentiate into extraembryonic trophectoderm and hypoblast.

49 mRNAs for both isoforms were detected in trophectoderm and ICM cells.

50 Genesis of the trophectoderm and inner cell mass (ICM) lineages occurs

51 the Grp78 promoter is activated in both the trophectoderm and inner cell mass (ICM) of embryos at em

52 without a protein source reduced blastocyst trophectoderm and inner cell mass cell number compared w

53 tocyst stage at day 7 and reduced numbers of trophectoderm and inner cell mass cells.

54 in growth arrest and cell death of both the trophectoderm and inner cell mass.

55 cRHOXF1 and which is abundantly expressed in trophectoderm and primitive endoderm cells of human blas

56 nce of the effects of parthenogenesis on the trophectoderm and primitive endoderm lineages.

57 y derived parthenogenetically, whereas their trophectoderm and primitive endoderm tissues were derive

58 eferential terminal differentiation of their trophectoderm and primitive endoderm.

59 whose progeny contributes more to the mural trophectoderm and that show compromised development when

60 es that appear before the segregation of the trophectoderm and the inner cell mass influence lineage

61 e is differentiated into two cell types, the trophectoderm and the inner cell mass.

62 distinct histone methylation patterns in the trophectoderm and the pluripotent epiblast.

63 -embryonic tissues that are derived from the trophectoderm and the primitive endoderm upon reintroduc

64 Two-way interactions between the blastocyst trophectoderm and the uterine luminal epithelium are ess

65 l division: symmetric that gives rise to the trophectoderm and then placenta or asymmetric that gives

66 ibute to the inner cell mass (ICM) and polar trophectoderm and undertake full development when combin

67 e attachment reaction between the blastocyst trophectoderm and uterine luminal epithelium that occurs

68 , mesoderm, endoderm, primordial germ cells, trophectoderm, and amnion.

69 ures of the epiblast, primitive endoderm and trophectoderm, and identify deeply conserved lineage-spe

70 e viable, hatch, form an inner cell mass and trophectoderm, and implant (roughly 4.5 dpc), indicating

71 able, hatched, formed an inner cell mass and trophectoderm, and implanted (E4.5), suggesting that the

72 ally cells with characteristics of endoderm, trophectoderm, and inner cell mass were observed in the

73 hment of the first differentiated cells, the trophectoderm, and of the pluripotent epiblast cells.

74 om three lineages: the maternal decidua, the trophectoderm, and the extra-embryonic mesoderm.

75 n influence the cell division pattern of the trophectoderm, and thereby affect cell allocation and fa

76 veloping mouse blastocyst, the growth of the trophectoderm, and/or the function of the embryonic epit

77 sage the inner cell mass and extra-embryonic trophectoderm are established when eight blastomeres com

78 cell masses ectopically activate a subset of trophectoderm-associated genes.

79 that formed under these conditions expressed trophectoderm-associated genes.

80 is demonstrates that Ron is expressed in the trophectoderm at embryonic day (E) 3.5 and is maintained

81 Outside cells become committed to the trophectoderm at the blastocyst stage through Cdx2 activ

82 5A2 and is also selectively expressed in the trophectoderm at the blastocyst stage.

83 cells (HEECs) impaired primary human embryo trophectoderm attachment in a 3-dimensional culture mode

84 cyst, laminin 1 is strongly expressed in the trophectoderm basement membrane, whereas laminin 10/11 i

85 dures by generating RNA-seq libraries from a trophectoderm biopsy as well as the remaining whole embr

86 t gold-standard methodology, especially when trophectoderm biopsy becomes a preferred option and geno

87 Moreover, applying trophectoderm biopsy, a mechanical procedure performed c

88 The trophectoderm boundary becomes essential for expansion o

89 Genes expressed in the trophectoderm but not in embryos prior to blastocyst for

90 a-embryonic lineages, primitive endoderm and trophectoderm, but not the embryonic lineage, before imp

91 mplantation due to Eomes requirements in the trophectoderm cell lineage.

92 pport the hypothesis that LGALS15 stimulates trophectoderm cell migration and attachment via integrin

93 zygous blastocysts is accompanied by reduced trophectoderm cell number and developmental delay and al

94 in the inner-cell mass without any change in trophectoderm cell number.

95 Its knockout decreases the proportion of trophectoderm cells and delays the morula to blastocyst

96 ocoel expansion and increasing the number of trophectoderm cells compared to controls.

97 y active ERK in both the inner cell mass and trophectoderm cells due to fibroblast growth factor (FGF

98 on in mammalian embryos segregates polarized trophectoderm cells from an apolar inner cell mass (ICM)

99 ope reduced the proliferation of mononuclear trophectoderm cells isolated from day 15 conceptuses.

100 Here, we demonstrate that trophectoderm cells of pre-implantation human and mouse

101 successful molecular interaction between the trophectoderm cells of the blastocyst stage embryo and t

102 ession of CDX2, thereby specifying the first trophectoderm cells of the embryo.

103 It is first expressed by trophectoderm cells of the late blastocyst and by all tr

104 At the late blastocyst stage, the epithelial trophectoderm cells of the mammalian embryo undergo a ph

105 biopsied at the blastocyst stage and several trophectoderm cells removed.

106 ateral membrane contact site between nascent trophectoderm cells usually during the early 32-cell sta

107 By contrast, in the differentiating trophectoderm cells where Oct4 expression is progressive

108 nts of this process are cell-cell contact of trophectoderm cells with uterine luminal epithelial cell

109 phosphorylation and nuclear translocation in trophectoderm cells without influencing Ca2+ channels, a

110 ncreasingly associated with cell membrane in trophectoderm cells, while at E4.5, Dishevelled 3 is hig

111 ectly required for gene silencing in ESCs or trophectoderm cells.

112 exhibited an apical staining pattern in the trophectoderm cells.

113 in is expressed at the apical surface of the trophectoderm cells.

114 ature of ZIKV susceptibility of hESC-derived trophectoderm cells.

115 RS-CoV-2, and we observe robust infection of trophectoderm cells.

116 potent stem cells (PSCs) toward progeny with trophectoderm characteristics, we produced transcriptome

117 discovery of the TEtra circuit indicates how trophectoderm commitment is regulated in human embryogen

118 ificant enrichment of aneuploid cells in the trophectoderm compared to the inner cell mass, although

119 Desmosomes first assemble in the E3.5 mouse trophectoderm, concomitant with establishment of epithel

120 In trophectoderm, de novo H3K9me3 domains prevent pluripote

121 ed to hatch or attach in vitro, indicating a trophectoderm defect, although the inner cell mass could

122 otransposon is upregulated in hypomethylated trophectoderm-derived cells that normally express Tex19.

123 Radiation sensitivity was demonstrated in trophectoderm-derived cells.

124 implying the importance of Grhl2 activity in trophectoderm-derived cells.

125 similar mechanisms operate in hypomethylated trophectoderm-derived components of the mammalian placen

126 ) trophoblast stem cells and in cells of the trophectoderm-derived extra-embryonic ectoderm in Eed(-/

127 Loss of Dp1 compromises the trophectoderm-derived tissues - specifically, the expans

128 derm cells of the late blastocyst and by all trophectoderm descendants in the early postimplantation

129 y has a developmental regulatory function in trophectoderm differentiation that may serve to coordina

130 o post-implantation derivatives of the polar trophectoderm - early-streak extra-embryonic ectoderm an

131 elopment trajectories of primitive endoderm, trophectoderm, epiblast lineages, and PGCLCs.

132 tocysts by incorporating all three lineages: trophectoderm, epiblast, and primitive endoderm.

133 de novo synthesis of tight junctions during trophectoderm epithelial differentiation.

134 and segregation of inner cell mass (ICM) and trophectoderm epithelium (TE) during blastocyst morphoge

135 Because cell-cell contact between the trophectoderm epithelium and the luminal epithelium is e

136 The trophectoderm epithelium is the first differentiated cel

137 ifferentiation and transport function of the trophectoderm epithelium which forms the wall of the bla

138 yst formation via direct contribution to the trophectoderm epithelium.

139 unction assembly and paracellular sealing in trophectoderm epithelium.

140 l mass, although under these conditions, the trophectoderm exhibits a 25% cellular accretion.

141 t cells whilst surrounding lineage-specified trophectoderm expresses EFNA ligands.

142 Although the key trophectoderm factors Id2, Elf5 and Eomes are exclusivel

143 lastocysts that upon dissection of the mural trophectoderm form egg cylinders in only 3 d.

144 sion of Cdx2, a transcription factor key for trophectoderm formation and cell polarity.

145 nd implicate Ras-MAPK signaling in promoting trophectoderm formation from mouse embryos.

146 at it participates only in the late stage of trophectoderm formation.

147 nscription factors, coined collectively the "trophectoderm four" (TEtra), which are also present in h

148 l stage, blastomeres begin to bifurcate into trophectoderm (future placenta) and inner cell mass (fut

149 s downregulated not only for extra-embryonic trophectoderm genes, such as CDX2, but also for regulato

150 d are essential for conceptus elongation and trophectoderm growth and development.

151 ekte sheep retroviruses (enJSRVs), regulates trophectoderm growth and differentiation in the periimpl

152 monstrate that the enJSRV envelope regulates trophectoderm growth and differentiation in the periimpl

153 SARS-CoV-2, are co-expressed in cells of the trophectoderm in blastocyst-stage preimplantation embryo

154 ogressive segregation of inner cell mass and trophectoderm in early blastocysts, and of epiblast and

155 ur" (TEtra), which are also present in human trophectoderm in vivo.

156 eloped a 3D model of the inner cell mass and trophectoderm in which individual cells were mapped into

157 In the trophectoderm, in which cells go through endocycles, the

158 yos reduced primitive endoderm and increased trophectoderm, indicating sequential exclusion by displa

159 Folding of this multi-layered trophectoderm induces spreading of the second extra-embr

160 However, ICM/polar trophectoderm intimacy is not maintained during post-imp

161 ve formation of the PDZ barrier and abnormal trophectoderm invasion.

162 We suggest that silencing of Oct-3/4 in trophectoderm is a prerequisite for hCG up-regulation in

163 vidence that the developmental switch to the trophectoderm is accompanied by the loss of Oct-4 silenc

164 The trophectoderm is the first extraembryonic tissue and doe

165 ell mass that forms the fetus, and the outer trophectoderm layer that forms the placenta(1).

166 In blastocysts, rafts were detectable in the trophectoderm layer, but could not be detected in the in

167 erential fate acquisition in the multipotent trophectoderm leading to the formation of a tissue bound

168 Brief induction of trophectoderm leads to formation of blastocyst-like stru

169 show that this reflects the accumulation of trophectoderm-like cells in both Rb and Rb;E2f4 mutant p

170 s a proxy, drives their differentiation into trophectoderm-like cells, enabling the identification of

171 m-like cells, a blastocoel-like cavity and a trophectoderm-like outer layer of cells.

172 nies reproducibly differentiated to an outer trophectoderm-like ring, an inner ectodermal circle and

173 Furthermore, this trophectoderm-like state could be captured, which enable

174 nce of a subpopulation of cells that enter a trophectoderm-like state during reprogramming.

175 e, Eomes is essential for development of the trophectoderm lineage and Eomes loss-of-function mutants

176 in embryonic stem cells (ESCs) and prevents trophectoderm lineage differentiation.

177 polarization to determine pluripotent versus trophectoderm lineage fate.

178 ation of two distinct stem cell types of the trophectoderm lineage from human pluripotent stem cells.

179 hanisms that operate upstream to specify the trophectoderm lineage have not been established.

180 TEAD4 is essential for specification of the trophectoderm lineage required for producing a blastocys

181 results demonstrate that TFAP2C facilitates trophectoderm lineage specification by functioning as a

182 or transcription factors associated with the trophectoderm lineage, and the existence of a subpopulat

183 nd 16-cell stage and then the maintenance of trophectoderm lineage-specific differentiation.

184 e uniquely required for specification of the trophectoderm lineage.

185 ryo and in stem cells of the extra-embryonic trophectoderm lineage.

186 ative of both isoforms was restricted to the trophectoderm lineage.

187 AD4 is not required for specification of the trophectoderm lineage.

188 human somatic cells, indicate a role for the trophectoderm-lineage-specific regulatory program during

189 y blastocyst), and later within both ICM and trophectoderm lineages (mid/late blastocyst), apparently

190 tribute both to the embryo proper and to the trophectoderm lineages in a chimaera assay.

191 the embryo to establish the pluripotent and trophectoderm lineages.

192 HRas1(Q61L) in ES cells in vitro induces the trophectoderm marker Cdx2 and enables derivation of trop

193 with the active transport of ions across the trophectoderm mediated by the sodium pump (Na+, K+, ATPa

194 ion leads to cell differentiation toward the trophectoderm, mesoderm, and germ cell lineages.

195 o cell lineages (the inner cell mass and the trophectoderm), migrates within the reproductive tract,

196 In contrast, in the trophectoderm, miRNAs maintain the trophoblast stem cell

197 immunostaining was most concentrated in the trophectoderm of blastocysts.

198 nes), which are expressed exclusively in the trophectoderm of bovine embryos.

199 IFN-tau is a secretory product of trophectoderm of cattle, sheep, and their relatives and

200 (ES) cells and in inner cell mass (ICM) and trophectoderm of cultured blastocysts.

201 ough the inner cell mass was unaffected, the trophectoderm of homozygous Eif2s1(tm1RjK) blastocysts e

202 AMOTL2 mRNA and protein was expressed in the trophectoderm of human and mouse blastocysts.

203 u (IFN-tau) genes is restricted to embryonic trophectoderm of ruminant ungulate species for a few day

204 TS) cells in the mouse derive from the polar trophectoderm of the blastocyst and persist through earl

205 es to differentiating primitive endoderm and trophectoderm of the blastocyst.

206 Analysis of microdissected trophectoderm of the bovine conceptuses revealed the pre

207 The enJSRV envelope gene is expressed in the trophectoderm of the elongating ovine conceptus after da

208 in the outer epithelial cell layer (chorion/trophectoderm) of the placenta.

209 rulae do not produce trophoblast stem cells, trophectoderm or blastocoel cavities, and therefore do n

210 sts, but is not required for the survival of trophectoderm or Sertoli cells.

211 ution of the resulting labeled clones to the trophectoderm or the inner cell mass in a subset of embr

212 ni1-null blastocysts fail to hatch, form the trophectoderm, or expand the inner cell mass when cultur

213 These results indicate that tissues of trophectoderm origin are unable to restore genomic impri

214 moderately increased proliferation of ovine trophectoderm (oTr) cells.

215 This approach retarded trophectoderm outgrowth during conceptus elongation and

216 n, delays blastocyst development and reduces trophectoderm outgrowth from embryo explants.

217 Inner cell mass icO(2) was lower than trophectoderm, perhaps reflecting limitations of diffusi

218 e epiblast (body), hypoblast (yolk sac), and trophectoderm (placenta).

219 nt of three cell lineages in the blastocyst: trophectoderm, primitive endoderm, and epiblast.

220 evealed spatially graded ERK activity in the trophectoderm prior to overt polar versus mural differen

221 Sendai virus infection of human trophectoderm progenitor cells increased lncRHOXF1 RNA l

222 ompartments of in vitro differentiated human trophectoderm progenitor cells.

223 ing small interfering RNAs (siRNAs) in human trophectoderm progenitors increased expression of viral

224 nner cell mass (ICM), SOX2 regulates the ICM-trophectoderm program but is dispensable for opening glo

225 ading but may also play a role in regulating trophectoderm proliferation and differentiation.

226 ckdown blastocysts exhibit a failure of both trophectoderm proliferation as well as a conspicuous lac

227 GF4 rescues primitive endoderm formation and trophectoderm proliferation in Suds3 knockdown blastocys

228 that mTOR is required for the initiation of trophectoderm protrusive activity.

229 Moreover, lack of Xm-XCI in the trophectoderm, rather than loss of paternally expressed

230 bset of these enhancers, associated with key trophectoderm-related transcription factor genes, is pri

231 0d was internalized by mouse embryos via the trophectoderm, resulting in an indirect overexpression o

232 stained during mitotic entry, which leads to trophectoderm rupture and blastocyst collapse.

233 aminoids continues to develop in response to trophectoderm-secreted IL-6.

234 pecific genes, Gata3 and Eomes, and also the trophectoderm-specific cytokeratin intermediate filament

235 abling the identification of CEBPa-regulated trophectoderm-specific enhancers.

236 pected role of Notch signaling in regulating trophectoderm-specific expression of Cdx2 in cooperation

237 Furthermore, expression of trophectoderm-specific genes, Gata3 and Eomes, and also

238 Tead4(-/-) embryos do not express trophectoderm-specific genes, such as Cdx2, but do expre

239 Elimination of zygotic expression of trophectoderm-specific transcription factor Cdx2 leads t

240 stage and might affect embryo compaction and trophectoderm specification.

241 at Cdx2 participates in two steps leading to trophectoderm specification: appropriate polarisation of

242 However, it is sustained in the trophectoderm, suggesting an evolutionarily conserved fu

243 ndicate that neither the inner cell mass nor trophectoderm survives.

244 Specification of the trophectoderm (TE) and inner cell mass (ICM) lineages in

245 These lineages derive from outer trophectoderm (TE) and internal primitive endoderm (PE)

246 is achieved by epithelial differentiation of trophectoderm (TE) and its segregation from the inner ce

247 The formation of trophectoderm (TE) and pluripotent inner cell mass (ICM)

248 l lineage commitment is the formation of the trophectoderm (TE) and the inner cell mass (ICM) lineage

249 at Klf5 is required for the formation of the trophectoderm (TE) and the inner cell mass (ICM), and fo

250 lian development is the establishment of the trophectoderm (TE) and the inner cell mass (ICM).

251 mammalian development are the extraembryonic trophectoderm (TE) and the primitive endoderm (PrE).

252 lk DNA sequencing (DNA-Seq) of multicellular trophectoderm (TE) and/or inner cell mass (ICM) samples.

253 ysts with existent inner cell mass (ICM) and trophectoderm (TE) cells underwent TE biopsy for PGT-A b

254 lastocyst composed of an inner cell mass and trophectoderm (TE) cells, the latter of which are progen

255 d the crosstalk between the epiblast and the trophectoderm (TE) during pig embryo elongation.

256 piblast (EPI), primitive endoderm (PrE), and trophectoderm (TE) fates in blastocyst chimeras and have

257 The segregation of the trophectoderm (TE) from the inner cell mass (ICM) in the

258 Intriguingly, the trophectoderm (TE) in preimplantation monkey blastocysts

259 em (ES) cells undergo differentiation to the trophectoderm (TE) lineage by repression of the ES cell

260 Trophectoderm (TE) lineage development is pivotal for pr

261 last stem cells (TS cells), derived from the trophectoderm (TE) of blastocysts, require transcription

262 ammalian embryo must differentiate to either trophectoderm (TE) or inner cell mass (ICM), followed by

263 morula stage, with outer cells initiating a trophectoderm (TE) placental progenitor program.

264 olarity such that the outer apical cells are trophectoderm (TE) precursors and the inner cell mass (I

265 stocyst activation, the process by which the trophectoderm (TE) receives extrinsic cues that initiate

266 two cell lineages, inner cell mass (ICM) and trophectoderm (TE), is dependent upon functions of key t

267 re present in the developing blastocyst: the trophectoderm (TE), the epiblast (Epi) and the primitive

268 ast and therefore the future embryo, and the trophectoderm (TE), which will build the placenta.

269 Human trophoblasts arise from the morula as trophectoderm (TE), which, after implantation, different

270 In the trophectoderm (TE), X inactivation was nonrandom with th

271 The trophectoderm (TE)-associated transcription factor CDX2

272 mbryo, TEAD4 is critical to establishing the trophectoderm (TE)-specific transcriptional program and

273 t inner cell mass (ICM) from differentiating trophectoderm (TE).

274 th an identifiable inner cell mass (ICM) and trophectoderm (TE).

275 nhibition also promotes differentiation into trophectoderm (TE).

276 consisting of the inner cell mass (ICM) and trophectoderm (TE).

277 e first lineage decision and form functional trophectoderm (TE).

278 expression between inner cell mass (ICM) and trophectoderm (TE).

279 nic inner cell mass (ICM) and the supportive trophectoderm (TE).

280 Using a multifocal biopsy approach (four trophectoderms [TEs] and one inner cell mass [ICM] analy

281 cortical tension and tissue stiffness of the trophectoderm that lines the lumen.

282 ues of the second extraembryonic tissue, the trophectoderm, the efficiency of bilaminoid formation in

283 e extra-embryonic primitive endoderm and the trophectoderm tissues.

284 progression lineage potential switches from trophectoderm to amnion.

285 oplasmic crystalline structures of conceptus trophectoderm (Tr).

286 the arginine transporter in ovine conceptus trophectoderm (Tr).

287 ed through Hippo and Notch in the blastocyst trophectoderm, unexpectedly finding that it is inactive

288 The presence of Ets-2 in nuclei of embryonic trophectoderm was confirmed immunocytochemically.

289 Once the trophectoderm was specified, Tead4 was not essential for

290 e phenotype cannot be rescued by a wild-type trophectoderm, we propose that UNC5B-mediated signaling

291 pment is the formation of an epithelium, the trophectoderm, we tested the hypothesis that one such em

292 me and cell number (both inner cell mass and trophectoderm) were also increased when the distance apa

293 isions, thereby allocating more cells to the trophectoderm, whereas reducing Cdx2 promotes asymmetric

294 he assembly of TJ-associated proteins within trophectoderm which, from our previous data, spans from

295 with formation of a blastocyst consisting of trophectoderm, which contributes exclusively to the plac

296 last, which generates the embryo proper; the trophectoderm, which generates the placenta; and the hyp

297 mammalian embryogenesis is that between the trophectoderm, which gives rise to the trophoblast of th

298 Subsequently, outer cells differentiate into trophectoderm while inner cells retain pluripotency to b

299 mouse embryo compaction, outer cells become trophectoderm, while inner cells form the inner cell mas

300 on mouse development, close contact of polar trophectoderm with the inner cell mass (ICM) promotes pr