ライフサイエンスコーパス: tropicalis

1 distantly related anuran amphibian (Xenopus tropicalis).

2 us), and 2 frogs (Xenopus laevis and Xenopus tropicalis).

3 tHEP2) from the Western clawed frog (Xenopus tropicalis).

4 naling during early embryogenesis in Xenopus tropicalis.

5 well as telomeres of seven chromosomes in C. tropicalis.

6 esents a novel group of major allergen in B. tropicalis.

7 y regulated by Ets1 in both X. laevis and X. tropicalis.

8 mportant roles in eye development in Xenopus tropicalis.

9 , a major allergen from the dust mite Blomia tropicalis.

10 ource for genetic and genomic analyses in X. tropicalis.

11 ng transcriptome of the related frog Xenopus tropicalis.

12 s gene ablates forelimb formation in Xenopus tropicalis.

13 esent a draft genome sequence assembly of X. tropicalis.

14 the dorsal embryonic spinal cord of Xenopus tropicalis.

15 and soma of the African clawed frog Xenopus tropicalis.

16 and genome-wide sequence analysis in Xenopus tropicalis.

17 lis (Xt) allurin, a homologous protein in X. tropicalis.

18 ies in the rapidly breeding diploid frog, X. tropicalis.

19 . glabrata, C. krusei, C. lusitaniae, and C. tropicalis.

20 s and developmental stages of X.laevis and X.tropicalis.

21 NTPDase family in Xenopus laevis and Xenopus tropicalis.

22 ecify initial competence in the frog Xenopus tropicalis.

23 chordin, noggin, and follistatin, in Xenopus tropicalis.

24 mportation of the West African frog, Xenopus tropicalis.

25 ts of the only diploid Xenopus frog, Xenopus tropicalis.

26 ral additional ones that are conserved in X. tropicalis.

27 reased proportion of Candida glabrata and C. tropicalis.

28 e unique to one subgenome and absent from X. tropicalis.

29 in the common ancestor of C. albicans and C. tropicalis.

30 bicans, C. glabrata, C. parapsilosis, and C. tropicalis.

31 ion in WT mice enhanced susceptibility to C. tropicalis.

32 s in vitro enhanced their ability to kill C. tropicalis.

33 for C. parapsilosis, 0.06 and 0.007; for C. tropicalis, 0.03 and 0.015; for C. krusei, 0.25 and 0.12

34 06, 99.9; C. parapsilosis, 0.5/0.5, 99.0; C. tropicalis, 0.03/0.06, 99.7; C. krusei, 0.12/0.5, 99.0;

35 ns, 0.015/0.03; C. glabrata, 0.015/0.015; C. tropicalis, 0.03/0.06; C. krusei, 0.06/0.12; C. kefyr, 0

36 psilosis, 0.12 (97.6) and 0.06 (97.2) for C. tropicalis, 0.5 (99.8) and 0.5 (99.4) for C. krusei, 0.1

37 r C. parapsilosis, 0.0, 1.5, and 0.5; for C. tropicalis, 0.9, 0.7, and 0.9; and for C. krusei, 0.5, 6

38 8.9%), 0.12 (99.4%), and 0.12 (99.1%) for C. tropicalis; 0.25(100%), 0.03 (100%), and 0.12 (100%) for

39 C. lusitaniae, 10 C. parapsilosis, and 5 C. tropicalis (1 fluconazole-resistant isolate) isolates.

40 ia mucosa (1), Escherichia coli (3), Candida tropicalis (1), Propionibacterium (1), and Rothia (1).

41 the isolates of C. albicans (0.4%), Candida tropicalis (1.3%), and Candida parapsilosis (2.1%); howe

42 brata (7.9%), C. parapsilosis (1.7%), and C. tropicalis (1.4%).

43 9%), Candida parapsilosis (17%), and Candida tropicalis (10%).

44 labrata (18.0%), C. parapsilosis (17.2%), C. tropicalis (10.5%), and C. krusei (1.9%).

45 arapsilosis (17.3%), C. glabrata (17.2%), C. tropicalis (10.9%), C. krusei (1.9%), and other Candida

46 osis, 100%; C. glabrata/C. krusei, 92.3%; C. tropicalis, 100%) and specificity (C. albicans/C. paraps

47 osis, 100%; C. glabrata/C. krusei, 94.8%; C. tropicalis, 100%).

48 C. glabrata, 99.9%, 99.9%, and 100%; for C. tropicalis, 100%, 99.8%, and 100%; for C. krusei, 100%,

49 labrata (24%), C. parapsilosis (13%), and C. tropicalis (12%).

50 owed by Candida glabrata (25.6%) and Candida tropicalis (16.3%).

51 (56.9%), with C. parapsilosis (25.6%) and C. tropicalis (17.0%) being more prominent in LAM.

52 apsilosis, 19 of C. guilliermondii, 12 of C. tropicalis (2 mutant strains), and 11 of C. krusei.

53 losis, 13.4% Candida glabrata, 10.1% Candida tropicalis, 2.4% Candida krusei, 1.7% Candida guilliermo

54 )/1 (90.5), and 0.5 (97.8)/0.5 (93.9) for C. tropicalis; 2 (99.3)/4 (100.0), 32 (99.4)/32 (99.3), and

55 6 C. glabrata, 1,238 C. parapsilosis, 996 C. tropicalis, 270 C. krusei, 99 C. lusitaniae, 88 C. guill

56 14% C. parapsilosis, 14% C. glabrata, 12% C. tropicalis, 3% C. krusei, 1% C. guilliermondii, and 2% o

57 14% C. glabrata, 14% C. parapsilosis, 11% C. tropicalis, 3% C. krusei, and 4% other Candida spp.

58 ns of Candida albicans (11 mutants), Candida tropicalis (4 mutants), Candida krusei (3 mutants), and

59 60 isolates of C. albicans (9 isolates), C. tropicalis (5 isolates), C. krusei (2 isolates), and C.

60 solates of Candida albicans (4 isolates), C. tropicalis (5 isolates), C. krusei (4 isolates), C. kefy

61 ans species C. glabrata (10.2% to 11.7%), C. tropicalis (5.4% to 8.0%), and C. parapsilosis (4.8% to

62 s (23.7%), Candida glabrata (12.7%), Candida tropicalis (5.8%), Candida krusei (4%), and others (1.8%

63 tes of C. parapsilosis, 1,895 isolates of C. tropicalis, 508 isolates of C. krusei, 205 isolates of C

64 C. parapsilosis, 1,048 (17.8%) isolates; C. tropicalis, 527 (8.9%) isolates; C. krusei, 109 (1.9%) i

65 or C. parapsilosis; 2, 0.12, and 0.06 for C. tropicalis; 64, 0.5, and 0.5 for C. krusei.

66 rusei, 91.6%; C. parapsilosis, 86.6%; and C. tropicalis, 86.4%.

67 labrata (14.8%), C. parapsilosis (12.5%), C. tropicalis (9.4%), C. krusei (2.7%), and C. lusitaniae (

68 dida albicans (2.7%), C. glabrata (4.1%), C. tropicalis (9.7%), and other less common yeast species (

69 .3% (95% CI, 85.4%-96.6%) for C. albicans/C. tropicalis, 94.2% (95% CI, 84.1%-98.8%) for C. parapsilo

70 parapsilosis; 99.2%, 99.2%, and 96.8% for C. tropicalis; 97.1%, 97.1%, and 97.1% for C. krusei.

71 I, 98.3%-99.4%) for Candida albicans/Candida tropicalis, 99.3% (95% CI, 98.7%-99.6%) for Candida para

72 e evaluated a systemic infection model of C. tropicalis, a clinically relevant, but poorly understood

73 ase to knockdown endogenous Dot1L in Xenopus tropicalis, a diploid species highly related to the well

74 n, we studied the oocyte of the frog Xenopus tropicalis, a giant cell with an equally giant nucleus.

75 duce TNF-alpha following stimulation with C. tropicalis Ags.

76 transgenic mouse, specific for the major B. tropicalis allergen Blo t 5, that targets the lung rathe

77 This difficulty exists in Xenopus tropicalis, an anuran quickly becoming a relevant model

78 In this study we investigate Candida tropicalis, an important human fungal pathogen that has

79 with two members in elephant shark, Xenopus tropicalis and Anolis lizard and three members in teleos

80 uced susceptibility to amphotericin B for C. tropicalis and C. glabrata.

81 rata, two of C. albicans, and one each of C. tropicalis and C. krusei were classified as susceptible

82 albicans mutants, and one mutant each of C. tropicalis and C. krusei were classified as susceptible

83 The limit of detection was 1 CFU/mL for C. tropicalis and C. krusei, 2 CFU/mL for C. albicans and C

84 accompanied by a concomitant increase in C. tropicalis and C. parapsilosis.

85 GPR12; GPRx orthologs are present in Xenopus tropicalis and Danio rerio, but apparently not in birds

86 underlying deep mesenchymal layer in Xenopus tropicalis and extend our previous findings for Xenopus

87 on profiles in developing zebrafish, Xenopus tropicalis and mice and suggests roles for Tet proteins

88 the phylotypic period in zebrafish, Xenopus tropicalis and mouse.

89 Interestingly, Candida tropicalis and the emerging fungal pathogen Candida auri

90 gE to Dermatophagoides pteronyssinus, Blomia tropicalis and their tropomyosins Der p 10 and Blo t 10

91 Comparison of X. tropicalis and X. laevis blots revealed comparable expre

92 ression of many identified miRNAs in both X. tropicalis and X. laevis.

93 g sequence from western clawed frog (Xenopus tropicalis) and zebrafish (Danio rerio).

94 glabrata, 20 Candida parapsilosis, 9 Candida tropicalis, and 1 each of Candida krusei and Candida lus

95 a, 46 C. albicans, 36 C. parapsilosis, 19 C. tropicalis, and 20 other species).

96 glabrata, 162 of C. parapsilosis, 124 of C. tropicalis, and 35 of C. krusei.

97 .3% of isolates for C. albicans, 6.2% for C. tropicalis, and 4.1% for C. parapsilosis).

98 a, 79 C. albicans, 23 C. parapsilosis, 18 C. tropicalis, and 49 other species) and 161 contrived samp

99 tes of C. parapsilosis, 1,841 isolates of C. tropicalis, and 503 isolates of C. krusei.

100 s, 38 C. glabrata, 10 C. parapsilosis, 12 C. tropicalis, and 7 C. krusei) against seven antifungal ag

101 labrata, 22 Candida parapsilosis, 14 Candida tropicalis, and 8 Candida krusei isolates), as determine

102 Fluconazole resistance in C. albicans, C. tropicalis, and C. parapsilosis isolates was low (1%), b

103 ant isolates of C. albicans, C. glabrata, C. tropicalis, and C. rugosa remained S to voriconazole.

104 ted of TNF-alpha were more susceptible to C. tropicalis, and CARD9-deficient neutrophils and monocyte

105 usitaniae, 4 were C. albicans, and 3 were C. tropicalis, and five isolates belonged to other Candida

106 e early development of the amphibian Xenopus tropicalis, and found that n1-src expression is regulate

107 of Candida albicans, Candida krusei, Candida tropicalis, and perhaps Candida glabrata.

108 s of X. laevis oocytes holds for those of X. tropicalis, and suggest that X. tropicalis oocytes offer

109 a spp., such as C. albicans, C. glabrata, C. tropicalis, and the C. parapsilosis group.

110 determining gene, DM-W, does not exist in X. tropicalis, and the sex chromosomes in the two species a

111 Candida albicans and Candida tropicalis are opportunistic fungal pathogens that can t

112 system, including the development of Xenopus tropicalis as a genetically tractable complement to the

113 athobiology and underscore the utility of X. tropicalis as a model system for understanding neurodeve

114 ng the T3-dependent metamorphosis in Xenopus tropicalis as a model, we show here that high levels of

115 parapsilosis, Candida glabrata, and Candida tropicalis as well as other clinical species.

116 etraploid Xenopus laevis and diploid Xenopus tropicalis, as a model for postembryonic development, a

117 kifugu rubripes, Xenopus laevis, and Xenopus tropicalis, as well as subpockets involved in protein in

118 krusei, Candida guilliermondii, and Candida tropicalis), Aspergillus fumigatus, Scedosporium spp., F

119 C. parapsilosis ATCC 22019 (25 to 36 mm), C. tropicalis ATCC 750 (23 to 33 mm), and C. krusei ATCC 62

120 da parapsilosis ATCC 22019 (22 to 33 mm), C. tropicalis ATCC 750 (26 to 37 mm), and C. albicans ATCC

121 Candida tropicalis ATCC 750 was not useful for this purpose.

122 ocytes were necessary for defense against C. tropicalis, because their depletion in WT mice enhanced

123 C. tropicalis biofilm formation was dependent on the pherom

124 The Blomia tropicalis (Blo t) mite species is considered a storage

125 form meiotic spindles similar in size to X. tropicalis but that TPX2 and katanin-mediated scaling is

126 t sexual biofilm formation also occurs in C. tropicalis but, unlike C. albicans, biofilms are formed

127 ted a chromosome-level genome assembly of C. tropicalis by employing PacBio sequencing, chromosome co

128 Candida albicans, C. glabrata, C. tropicalis, C. krusei, and C. kefyr were the most suscep

129 a albicans, C. glabrata, C. parapsilosis, C. tropicalis, C. krusei, and C. lusitaniae; these account

130 . albicans, C. glabrata, C. parapsilosis, C. tropicalis, C. krusei, C. lusitaniae, and C. guilliermon

131 nt among the methods for all C. albicans, C. tropicalis, C. lusitaniae, and C. krusei isolates.

132 strate that C. albicans, C. dubliniensis, C. tropicalis, C. parapsilosis, and C. glabrata release bon

133 andida species (C. albicans, C. glabrata, C. tropicalis, C. parapsilosis, and C. krusei) account for

134 e-R isolates of C. albicans, C. glabrata, C. tropicalis, C. rugosa, C. lipolytica, C. pelliculosa, C.

135 nd in C. albicans serotypes A and B, Candida tropicalis, Candida guilliermondii, Candida glabrata, an

136 occus sanguis, Streptococcus mutans, Candida tropicalis, Candida parapsilosis, Candida krusei, Candid

137 (Candida albicans, Candida glabrata, Candida tropicalis, Candida parapsilosis, Candida lusitaniae, Ca

138 eronyssinus, Dermatophagoides farina, Blomia tropicalis, cat, German cockroach, Oriental cockroach, c

139 ted high-affinity telomere DNA binding by C. tropicalis Cdc13 (CtCdc13) and found that dimerization o

140 rican (Xenopus laevis) and Western (Silurana tropicalis) clawed frogs.

141 at interaction of FoxG1 with TLE2, a Xenopus tropicalis co-repressor of the Groucho/TLE family, is cr

142 rter spindles observed in egg extracts of X. tropicalis compared to X. laevis.

143 We present a genetic map for Xenopus tropicalis, consisting of 2886 Simple Sequence Length Po

144 ke that of other tetrapods, the genome of X. tropicalis contains gene deserts enriched for conserved

145 divergence increases between X.laevis and X.tropicalis differences in mRNA expression levels also in

146 king CARD9 were profoundly susceptible to C. tropicalis, displaying elevated fungal burdens in viscer

147 Strikingly, young X. tropicalis DNA transposons are derepressed and recruit p

148 Xenopus tropicalis dril1 morphants also exhibit impaired gastrul

149 (H) chain (delta) from the amphibian Xenopus tropicalis during examination of the IgH locus.

150 The Blomia tropicalis dust mite is prevalent in tropical and subtro

151 GF8 performs a dual role in X. laevis and X. tropicalis early development.

152 We show that X. tropicalis egg extracts reconstitute the fundamental cel

153 ial of MMI and PTU using a validated Xenopus tropicalis embryo model.

154 Na(+), K(+)-ATPase beta3 subunit in Xenopus tropicalis embryos and show that its levels are downregu

155 ts of aquatic exposure of Silurana (Xenopus) tropicalis embryos to commercial NA extracts and from th

156 ntal Cell, Akkers et al. report that Xenopus tropicalis embryos transition through early development

157 Superficially, Xenopus tropicalis embryos with reduced levels of XEgr-1 resembl

158 In both cultured cells and X. tropicalis embryos, membrane-bound Ephrins (Efns) B1 and

159 ng (RNA-Seq) on wild-type and ets1 mutant X. tropicalis embryos.

160 on, and Nodal signal transduction in Xenopus tropicalis embryos.

161 ding' strategy for the collection of Xenopus tropicalis embryos.

162 28% C. albicans, 27% C. parapsilosis, 26% C. tropicalis, etc.) were evaluated between January 2012 an

163 Here we describe the analysis of 219,270 X. tropicalis expressed sequence tags (ESTs) from four earl

164 cent sequencing of a large number of Xenopus tropicalis expressed sequences has allowed development o

165 that a single intranasal sensitization to B. tropicalis extract induces strong Th2 priming in the lun

166 In both X. tropicalis extracts and the spindle simulation, a balanc

167 d that microtubules polymerized slower in X. tropicalis extracts compared to X. laevis, but that this

168 deed, TPX2 was threefold more abundant in X. tropicalis extracts, and elevated TPX2 levels in X. laev

169 edicted transcription start sites in Xenopus tropicalis for genome wide identification of TR binding

170 haromyces pombe, Xenopus laevis, and Xenopus tropicalis formed stable homotetramers, the mtSSBs from

171 y ChIP-seq and RNA-seq approaches in Xenopus tropicalis gastrulae and find that occupancy of the core

172 that tsg acts as a BMP antagonist during X. tropicalis gastrulation since the tsg depletion phenotyp

173 Scaffolds from X. tropicalis genome assembly 2.0 (JGI) were scanned for Si

174 Comparisons of this map with the X. tropicalis genome Assembly 4.1 (JGI) indicate that the m

175 ude the Xenopus laevis genome, a new Xenopus tropicalis genome build, epigenomic data, collections of

176 id in completing the assembly of the Xenopus tropicalis genome but will also serve as a valuable reso

177 With the advent of the Xenopus tropicalis genome project, we analyzed scaffolds contain

178 representation of a minimum of 66% of the X. tropicalis genome, incorporating 758 of the approximatel

179 RNAs and large piRNA clusters in the Xenopus tropicalis genome, some of which resemble the Drosophila

180 gy, we identified unique SSLPs within the X. tropicalis genome.

181 a newly recognized "Crisp A" gene in the X. tropicalis genome.

182 me and compared it to the related diploid X. tropicalis genome.

183 Here we use a library of Xenopus tropicalis genomic sequences in bacterial artificial chr

184 developing aquatic species, such as Xenopus tropicalis, goldfish, and zebrafish, and in Arabidopsis

185 en together, our results demonstrate that C. tropicalis has a unique sexual program, and that entry t

186 of N-ethyl-N-nitrosourea mutagenized Xenopus tropicalis has identified an inner ear mutant named ecli

187 cytoplasm between Xenopus laevis and Xenopus tropicalis have been shown to account for spindle scalin

188 Forward genetic screens in Xenopus tropicalis have identified more than 80 mutations affect

189 ly related frogs, Xenopus laevis and Xenopus tropicalis, have surprisingly different microtubule dyna

190 kinase pathway to activate sperm, whereas C. tropicalis hermaphrodites use a TRY-5 serine protease pa

191 toreceptors in retinas of developing Xenopus tropicalis heterozygous, but not homozygous mutant tadpo

192 On the other hand, X. tropicalis, highly related to X. laevis, offers a number

193 ce RNAs (sisRNAs) have been found in Xenopus tropicalis, human cell lines, and Epstein-Barr virus; ho

194 seq) to explore the transcriptome of Xenopus tropicalis in 23 distinct developmental stages.

195 s in 65% of patients, C. glabrata in 21%, C. tropicalis in 9%, C. parapsilosis in 3%, and C. guillier

196 is the first report of Inonotus (Phellinus) tropicalis inciting human disease and describes the meth

197 ons in TRIO GEFD1 in the vertebrate model X. tropicalis induce defects that are concordant with the h

198 irected against an eGFP transgene in Xenopus tropicalis induced mutations consistent with nonhomologo

199 re was no difference in susceptibility to C. tropicalis infection between WT and IL-23p19(-/-), IL-17

200 Thus, protection against systemic C. tropicalis infection requires CARD9 and TNF-alpha, but n

201 miting fungal disease during disseminated C. tropicalis infection.

202 ced normally in CARD9(-/-) mice following C. tropicalis infection.

203 p region as bottle cells whereas those in X. tropicalis ingress by "relamination".

204 To establish X. tropicalis intestinal metamorphosis as a model for adult

205 morphological and cytological changes in X. tropicalis intestine during metamorphosis.

206 m Dermatophagoides mites, confirming that B. tropicalis is a major and distinct source of dust mite a

207 Hence, X. tropicalis is a useful model for the study of molecular

208 The western clawed frog Xenopus tropicalis is an important model for vertebrate developm

209 standing the sex-determination systems in X. tropicalis is critical for developing this flexible anim

210 nopus, and in particular the diploid Xenopus tropicalis, is also ideal for functional genomics.

211 Candida parapsilosis, and 5 (11.9%) Candida tropicalis isolates and 1 (2.4%) Cryptococcus neoformans

212 , compared to < 1% of C. parapsilosis and C. tropicalis isolates and no C. glabrata isolates.

213 of C. parapsilosis isolates, and 0.4% of C. tropicalis isolates.

214 d to 7% of C. glabrata isolates and 6% of C. tropicalis isolates.

215 o 19.5% of C. glabrata isolates and 6% of C. tropicalis isolates.

216 nce breakpoint were also not observed for C. tropicalis isolates.

217 tations were found in 5 C. glabrata and 2 C. tropicalis isolates; of these, 5 (including all C. glabr

218 In X. tropicalis, k-fiber MT bundles that connect to chromosom

219 Human disease features are replicated in X. tropicalis larvae with morpholino knockdowns, in which e

220 We generated a transgenic X. tropicalis line that expresses enhanced green fluorescen

221 ilar metamorphic changes in X. laevis and X. tropicalis, making it possible to use the large amount o

222 In contrast, C. tropicalis mating occurs efficiently at both 25 degrees

223 calis model system and assessed whether an X.tropicalis microarray platform can be used for X.laevis.

224 In contrast, X. tropicalis microtubules grow slower and catastrophe more

225 Analysis of Xenopus tropicalis miRNA genes revealed a predominate positionin

226 es, more than 300 genes encoding 142 Xenopus tropicalis miRNAs were identified.

227 vis model system and the increasingly used X.tropicalis model system and assessed whether an X.tropic

228 icans (n = 22), C. parapsilosis (n = 10), C. tropicalis (n = 1) C. glabrata (n = 22), C. krusei (n =

229 All C. albicans (n = 12), C. tropicalis (n = 12), C. glabrata (n = 9), and C. krusei

230 29.8%), C. parapsilosis (n = 59; 14.1%), C. tropicalis (n = 37; 8.8%), and C. krusei (n = 17; 4.1%).

231 cans (n = 124), C. parapsilosis (n = 44), C. tropicalis (n = 41), C. glabrata (n = 36), C. krusei (n

232 ata (n = 722), C. parapsilosis (n = 666), C. tropicalis (n = 528), C. krusei (n = 143), C. lusitaniae

233 , Saccharomyces cerevisiae ( n = 9), Candida tropicalis (n = 8), Candida lusitaniae (n = 1), and Tric

234 an essential regulator of human and Xenopus tropicalis neural crest specification.

235 Oocytes of Xenopus tropicalis offer several practical advantages over those

236 for embryogenesis and premetamorphosis in X. tropicalis On the other hand, knocking out EVI and MDS/E

237 were C. glabrata, two isolates were Candida tropicalis, one isolate was Candida albicans, and one is

238 toplasm ("MPF activity") into G2-arrested X. tropicalis oocytes induces entry into meiosis I even whe

239 those of X. tropicalis, and suggest that X. tropicalis oocytes offer a good experimental system for

240 ocalizing RNAs in Xenopus laevis and Xenopus tropicalis oocytes, revealing a surprisingly weak degree

241 Together, these studies reveal that C. tropicalis opaque cells form sexual biofilms with a comp

242 -2.44; P = .001), and infection with Candida tropicalis (OR, 1.64; 95% CI, 1.11-2.39; P = .01) as pre

243 Approximately 30% (in Xenopus tropicalis) or 20% (in Xenopus laevis) of injected embry

244 mia caused by a DA producer, C. albicans, C. tropicalis, or C. parapsilosis.

245 C. glabrata, C. parapsilosis, C. rugosa, C. tropicalis, or Saccharomyces cerevisiae grown under cond

246 gene and its unequivocal Silurana (Xenopus) tropicalis orthologue, SNC10.

247 that the genetically tractable frog Xenopus tropicalis, paired with optical coherence tomography ima

248 ences but a closely related species, Candida tropicalis, possesses homogenized inverted repeat (HIR)-

249 utionary conservation, with X. laevis and X. tropicalis possessing distinct and unique alterations.

250 We (i) show that the X.tropicalis probes provide an efficacious microarray plat

251 d cell biological experiments, the use of X. tropicalis provides novel insight into the complex mecha

252 usei, C. lusitaniae, C. parapsilosis, and C. tropicalis) ranged from 97.1 to 100% and 99.8 to 100%, r

253 We describe here a Xenopus tropicalis rax mutant, the first mutant analyzed in deta

254 Here we identify X. tropicalis' sex chromosome system by integrating data fr

255 Structural analysis of C. tropicalis sexual biofilms revealed stratified communiti

256 ubule severing protein katanin scales the X. tropicalis spindle smaller compared to X. laevis [2], as

257 Small Xenopus tropicalis spindles resisted inhibition of two factors e

258 Interestingly, X. tropicalis spindles were approximately 30% shorter than

259 The crystal structure of the Candida tropicalis Stn1N complexed with Ten1 demonstrates an Rpa

260 a virtually identical architecture as the C. tropicalis Stn1N-Ten1.

261 cribe the expression and activity of Xenopus tropicalis Sulf2 (XtSulf2), which like XtSulf1, can act

262 or cervical ganglion and the tail of Xenopus tropicalis tadpoles are remodeled.

263 s supported by injecting the tail of Xenopus tropicalis tadpoles with peptide 4.2, a 20-aa sequence d

264 sing NPCs isolated from regenerating Xenopus tropicalis tails.

265 heterotaxy, and now demonstrate, in Xenopus tropicalis, that galnt11 activates Notch signalling.

266 stickleback and fugu, the amphibian Xenopus tropicalis, the monotreme platypus and the marsupial opo

267 In B. tropicalis, the most prevalent and allergenic allergens

268 Y/PRINCIPAL FINDINGS: We observed that in X. tropicalis, the premetamorphic intestine was made of mai

269 model of respiratory sensitization to Blomia tropicalis, the principal asthma allergen in the tropics

270 We show that in Xenopus tropicalis, these processes are connected to the outer-s

271 to knockdown expression of xtBcor in Xenopus tropicalis, thus creating an animal model for OFCD syndr

272 nce information and genetic advantages of X. tropicalis to dissect the pathways governing adult intes

273 different vertebrates, ranging from Xenopus tropicalis to Homo sapiens, demonstrating that there is

274 Significantly, we demonstrate that C. tropicalis uses a phenotypic switch to regulate a crypti

275 S. aureus coinoculated with C. krusei or C. tropicalis was highly lethal, similar to C. albicans, wh

276 this gene, we used the diploid frog Xenopus tropicalis We discover that Dyrk1a is expressed in cilia

277 ated knockdown in Xenopus laevis and Xenopus tropicalis we show that Nkx6.1 knockdown results in para

278 enesis in X. laevis and gene knockdown in X. tropicalis, we demonstrate that endogenous Dot1L is crit

279 Using Xenopus tropicalis, we have undertaken the first analysis of the

280 a model induced by intranasal exposure to B. tropicalis, we observed that a single intranasal sensiti

281 Tested using Xenopus tropicalis, we show that founders containing transplants

282 first positional cloning of a mutation in X. tropicalis, we show that non-contractile hearts in muzak

283 Using morpholino oligonucleotides in Xenopus tropicalis, we show that reducing tsg gene product resul

284 l strains of C. albicans, C. glabrata and C. tropicalis were evaluated.

285 Larvae of Silurana tropicalis (Western clawed frog) were exposed to DY7-con

286 early nervous system development in Xenopus tropicalis, where ZIP12 antisense morpholino knockdown i

287 ant-based protocols, and the diploid Xenopus tropicalis which is used for genetics and gene targeting

288 cluding C. glabrata, C. dubliniensis, and C. tropicalis, which are frequently more resistant to antif

289 vis and its smaller diploid relative Xenopus tropicalis, which contains smaller cells and nuclei.

290 Xenopus tropicalis, which is a small, faster-breeding relative o

291 in-dependent MT severing was increased in X. tropicalis, which, unlike X. laevis, lacks an inhibitory

292 xposure favored growth of C. glabrata and C. tropicalis, while caspofungin generally favored signific

293 was lowest for Candida glabrata and Candida tropicalis with both test systems.

294 Here, we coupled the frog Xenopus tropicalis with Optical Coherence Tomography (OCT) to cr

295 against C. albicans, C. parapsilosis, and C. tropicalis, with both former agents being more potent (M

296 mly in embryos of Xenopus laevis and Xenopus tropicalis, with prominent expression in the notochord,

297 e epigenome and the enhancer landscape in X. tropicalis x X. laevis hybrid embryos.

298 CRISPR/Cas9 gene editing outcomes in Xenopus tropicalis, Xenopus laevis, and zebrafish.

299 urification, and characterization of Xenopus tropicalis (Xt) allurin, a homologous protein in X. trop

300 the cryo-EM structure of OTOP3 from Xenopus tropicalis (XtOTOP3) along with functional characterizat

301 ntified two genes for each family in Xenopus tropicalis: Xtsprouty1, Xtsprouty2, Xtspred1, and Xtspre