ライフサイエンスコーパス: troublesome

1 remaining susceptibility alleles is proving troublesome.

2 ic lung allograft dysfunction (CLAD) remains troublesome.

3 tial between groups) becomes challenging and troublesome.

4 ostdental procedure bacteremia is common and troublesome.

5 antation, but patient stratification remains troublesome.

6 d be compared makes the finding of SNPs more troublesome.

7 , and to define which of their symptoms were troublesome.

8 cyl analogues in a fashion that obviates the troublesome acylation of the free 2-aminoimidazoles, whi

9 (CRF) remains one of the most prevalent and troublesome adverse events experienced by patients with

10 Fatigue is common and troublesome among breast cancer survivors; however, limi

11 he time of interview, only 1 person found it troublesome and 7 reported it as a minimal problem.

12 s to slow down biomolecular transport can be troublesome and are at odds with the natural goal of hig

13 quaternary carbon-containing oxiranes can be troublesome and difficult to achieve.

14 ration has resulted in methods that are both troublesome and inaccurate.

15 ith Acinetobacter baumannii, one of the most troublesome and least studied multidrug-resistant superb

16 g the sensitized transplant candidate can be troublesome and much remains to be understood about the

17 Stimulation-induced dysarthria (SID) is a troublesome and potentially therapy-limiting side effect

18 using and separating a new set of particles, troublesome and time-consuming design, fabrication, test

19 that emanate from human skin for analysis is troublesome and time-consuming.

20 l cases, the oscillopsia resolved or was not troublesome, and only 1 patient found it bothersome more

21 n and disabling in Parkinson's disease, with troublesome anxiety occurring in one-third of patients.

22 depression, symptoms which are frequently as troublesome as the motor symptoms of PD.

23 The most troublesome aspects of behavioral and psychological symp

24 y quiescent" state, while also removing some troublesome aspects of microfluidics including the use o

25 Most people with troublesome asthma are treated with inhaled corticostero

26 stone proteins represent the most common and troublesome barrier to transcription elongation.

27 The process is troublesome because its product is not resolved from 13C

28 The diagnosis is often troublesome because pericardial fluid analysis or biopsy

29 Thanks to this, troublesome brushes in HTS machines or bulky currents le

30 o demonstrate the enduring relevance of this troublesome, but always captivating, phenomenon in solid

31 m-catalyzed allylic reduction to install the troublesome C13-C15 segment.

32 in appears to have substantial activity, but troublesome cardiac toxicity has been noted in a recentl

33 Chronic rhinosinusitis (CRS) is a troublesome, chronic inflammatory disease that affects o

34 The suppression of signal for even the most troublesome combination of light analyte and heavy matri

35 e atrial fibrillation (POAF) is a common and troublesome complication of cardiac surgery.

36 ssessment, prevention, and treatment of this troublesome complication.

37 tomotic leak, and ileus, the most common and troublesome complications after colorectal surgery.

38 Diarrhea is one of the troublesome complications of diabetes, and the underlyin

39 A simple method to remove these troublesome contaminants is described.

40 t is then shed from the cell, along with the troublesome defect.

41 tment intensity, this study sheds light on a troublesome dilemma that clinicians face.

42 removal, NOB have been more considered as a troublesome disruptor, and strategies on NOB suppression

43 ncreases in patient-reported ON-time without troublesome dyskinesia (1.6, 3.3, and 1.5 hours, respect

44 ficantly greater increase in on time without troublesome dyskinesia (model-based mean [SE] 2.72 [0.52

45 from baseline to week 12 in on time without troublesome dyskinesia and off time, respectively; both

46 tions, with benefits in both on time without troublesome dyskinesia and off time.

47 otor fluctuations to improve on time without troublesome dyskinesia and reduce wearing off.

48 levodopa-carbidopa increased on time without troublesome dyskinesia and reduced off time, with a favo

49 We assessed change in motor on-time without troublesome dyskinesia as a prespecified key secondary o

50 2 h (95% CI 1.08 to 2.36) of on time without troublesome dyskinesia compared with oral levodopa-carbi

51 Mean on-time without troublesome dyskinesia increased by 4.11 h (SE 0.75) in

52 levodopa who experienced at least 1 hour of troublesome dyskinesia per day with at least mild functi

53 Mean (SD) change in daily on time without troublesome dyskinesia was +1.42 (2.80) hours for safina

54 mean increase; p=0.0250) in on time without troublesome dyskinesia were seen.

55 e in daily good on-time (ie, on-time without troublesome dyskinesia) from baseline to the end of the

56 e-blind phase in total daily on time without troublesome dyskinesia, analysed by intention to treat.

57 lief of parkinsonian motor features) without troublesome dyskinesia, as assessed from diary data.

58 ul reduction in "off" time without increased troublesome dyskinesia.

59 t-randomisation in increased ON time without troublesome dyskinesias between the active and control g

60 ses suggested improvement in on-time without troublesome dyskinesias with DT-aDBS compared to cDBS.

61 when symptoms were well controlled) without troublesome dyskinesias with no less than 1-SD reduction

62 urs per day with good symptom control and no troublesome dyskinesias, with no increase in anti-parkin

63 ef is highly variable and some cases develop troublesome dyskinesias.

64 ent, particularly the motor fluctuations and troublesome dyskinetic side effects.

65 NSAIDs with past or current peptic ulcer or troublesome dyspepsia led to impaired healing of gastric

66 y, 180-degree LAF has been alleged to reduce troublesome dysphagia and gas-related symptoms, with sim

67 er 3 years at 2 centers enrolled adults with troublesome esophageal symptoms of heartburn, regurgitat

68 Hot flashes can be troublesome, especially when hormonal therapy is contrai

69 ndous economic losses, and may become a more troublesome factor due to global warming.

70 n eight patients with multiple sclerosis and troublesome fatigue, before and after treatment with 3,4

71 If symptoms are troublesome, Fludrocortisone and B-blockers remain the f

72 Reads that are sometimes troublesome for antibodies are achieved.

73 nd the cell's energy supplies - particularly troublesome for energy-demanding cells of nervous tissue

74 vity, resulting in short duty times which is troublesome for many field applications.

75 ment areas during wintertime, which would be troublesome for PM2.5-burdened areas, and much lower inc

76 uce through traditional Wittig protocols and troublesome for the two previous total syntheses.

77 , for most patients and families facing this troublesome form of copper deficiency.

78 Other data suggest that this troublesome gene region has noncoding RNA functions, pos

79 netobacter baumannii has emerged as a highly troublesome, global pathogen.

80 of 84 patients with pituitary tumour who had troublesome headache were investigated.

81 cancer survivors had a higher prevalence of troublesome hearing (adjusted odds ratio [AOR], 1.43; 95

82 The weighted prevalence of subjective HL (troublesome hearing and tinnitus) and objective HL (spee

83 garding whether the participants were having troublesome hearing and/or tinnitus in screening for HL,

84 x disease (GERD) is defined by recurrent and troublesome heartburn and regurgitation or GERD-specific

85 rnate therapeutic target, in one of the most troublesome hospital-acquired pathogens.

86 toxicology models are often limiting and/or troublesome (i.e. short life-span reduced metabolic acti

87 Despite the troublesome impact of noise-induced hearing loss (NIHL)

88 This is particularly troublesome in global parameter tuning, routinely conduc

89 This is especially troublesome in lung and airway samples, in which histolo

90 ation enhances quantum yields while blocking troublesome interactions between fluorochromes and biomo

91 asions and offered as a reason not to manage troublesome invaders.

92 Most troublesome is the observation that cancer cells that su

93 nduit obstruction as well as arrhythmias and troublesome late mortality are significant limitations.

94 Troublesome lung symptoms and common infections in the f

95 uantitative global assessment of significant troublesome lung symptoms during the first 3 years of li

96 of life each time the child had significant troublesome lung symptoms for 3 days.

97 uantitative global assessment of significant troublesome lung symptoms in the first 3 years of life i

98 airway secretions sampled during episodes of troublesome lung symptoms in the first 3 years of life.

99 umber of acute clinic visits for significant troublesome lung symptoms was also significantly associa

100 istent wheeze, but the number of episodes of troublesome lung symptoms was reduced, and the airway im

101 genic bacteria identified during episodes of troublesome lung symptoms were associated with increased

102 dary outcomes included number of episodes of troublesome lung symptoms, asthma, respiratory tract inf

103 Adverse effects of troublesome major elements (Fe(3+), Ti) are circumvented

104 One of the most troublesome medical problems today is infection of prost

105 Lane et al. are right: Troublesome memories can be therapeutically recontextual

106 argets owing to their prevalence in the most troublesome multidrug-resistant pathogens(1,4,5).

107 Moderately troublesome musculoskeletal pain at age 17.8 years was r

108 ith an increased risk of at least moderately troublesome musculoskeletal pain at the shoulder (odds r

109 Despite their troublesome nature, little is known about the host or ba

110 GERD diagnostic tests in evaluation of these troublesome, nonesophageal symptoms.

111 One patient reported an extremely troublesome nose bleed (oxygen group).

112 r baumannii has recently emerged as a highly troublesome nosocomial pathogen, especially in patients

113 ependent nature of this process leads to the troublesome observation that the membrane resistor-capac

114 an internal standard in the sample is either troublesome or can change the sample characteristics.

115 nal methods, and issues that are potentially troublesome or sensitive for Native Americans.

116 tes of emergent incisional hernia repair are troublesome owing to the significantly increased risk mo

117 membrane-based therapeutic targeting of this troublesome pathogen.

118 ween two ecologically related and clinically troublesome pathogens, the prokaryote, Acinetobacter bau

119 ortex suggesting a common pathology of these troublesome perceptual impairments.

120 x surgery include the frequent appearance of troublesome postoperative dysphagia.

121 The most troublesome problem has been leak of blood around the gr

122 This is an especially troublesome problem in the context of a genome scan, sin

123 Here, we highlight some common and troublesome problems in the literature, and suggest meth

124 en dependent upon several time consuming and troublesome procedures.

125 Illuminating the path to degrading troublesome proteins.

126 ovide potential radioligands that may resist troublesome radiodefluorination during the imaging of br

127 x situ technologies to treat one of the most troublesome, recalcitrant and ubiquitous classes of envi

128 Those with at least troublesome regurgitation (based on the Montreal definit

129 , 65% (13/20) reported global elimination of troublesome regurgitation and atypical symptoms post TF

130 isease (GERD; age, 32-60 y; 7 women) without troublesome regurgitation and supraesophageal symptoms a

131 We screened 696 patients with troublesome regurgitation despite daily PPI use with 3 v

132 y intention-to-treat analysis, TF eliminated troublesome regurgitation in a larger proportion of pati

133 -controlled trial to determine if TF reduced troublesome regurgitation to a greater extent than PPIs

134 toms post TF off PPIs; 67% (6/9) reported no troublesome regurgitation.

135 that skin test scores identify patients with troublesome rejection.

136 Around 50% of users with troublesome rhinitis and/or ocular symptoms suffered wor

137 tures quantitative metal extraction, even in troublesome sample matrixes, such as seawater, salt, and

138 ecrease in metasurface components leading to troublesome scattering into unwanted directions.

139 ted by a combination of limited efficacy and troublesome side effects and has recently been challenge

140 Intestinal mucositis is one of the major troublesome side effects of anticancer chemotherapy lead

141 eir therapeutic efficacy is limited by their troublesome side effects resulting in the non-continuanc

142 ose or chronic administration often triggers troublesome side effects such as metabolic syndrome and

143 r gastroesophageal reflux can be followed by troublesome side effects.

144 is administered subcutaneously and can have troublesome side effects.

145 flux, but in some patients it is followed by troublesome side effects.

146 Nausea and vomiting is a troublesome side-effect that occurs more frequently duri

147 ifically and also more selectively, to avoid troublesome side-effects.

148 oural intervention had a sustained effect on troublesome subacute and chronic low-back pain at a low

149 lysis undertaken in England, 701 adults with troublesome subacute or chronic low-back pain were recru

150 In contrast to conventional troublesome sulfonamide hydrolysis, a near-stoichiometri

151 Cough is a common and troublesome symptom in asthmatic patients, but little is

152 Itch is the most troublesome symptom of atopic dermatitis, and it is impo

153 kin disease associated with itch, which is a troublesome symptom with a few therapeutic options.

154 Cough in asthmatic patients is a common and troublesome symptom.

155 ubscale; a visual analogue scale of the most troublesome symptom; and the Clinical Global Impression

156 (GERD) is a common disorder characterized by troublesome symptoms (classically, heartburn and regurgi

157 te between troublesome symptoms (TS) and non-troublesome symptoms (NTS).

158 rms of their ability to discriminate between troublesome symptoms (TS) and non-troublesome symptoms (

159 Sleep was impaired by troublesome symptoms and nasal obstruction.

160 uropathy, and pain are among the most common troublesome symptoms experienced by cancer survivors.

161 y, frequency and incomplete emptying are the troublesome symptoms often shared between benign prostat

162 in COPD could include: services triggered by troublesome symptoms such as refractory breathlessness;

163 aematological malignancies (n=224), the most troublesome symptoms were fatigue (mean score 5.2, SD 2.

164 Troublesome symptoms were found mainly in the users with

165 a common IgE-mediated disorder that produces troublesome symptoms.

166 uld fill an important void for patients with troublesome symptoms.

167 y population, with pruritus being one of the troublesome symptoms.

168 s have suffered from various issues, such as troublesome syntheses, high toxicity, poor stability or/

169 t arthritis disability is more extensive and troublesome than heart disease disability.

170 the subfamily Physinae have been especially troublesome to identify because morphological variation

171 phenotype manifests itself in a spectrum of troublesome to life-threatening diseases, from seasonal

172 ire complicated revision procedures that are troublesome to patients and costly to the healthcare sys

173 eloproliferative neoplasm (MPN) symptoms are troublesome to patients, and alleviation of this burden

174 The most frequent and troublesome toxicity, weight gain, was dose-related, wit

175 plexes, but absolute identification is still troublesome, usually requiring a chemical reaction with

176 to dramatically increase our control of this troublesome virus.

177 Johnsongrass (Sorghum halepense) is a troublesome weed in row crop production in the United St

178 copious seed producer, Poa annua is the most troublesome weed of turfgrass and continually threatens

179 are two troublesome weeds in the northern region of Australia.

180 and Amaranthus hybridus (smooth pigweed) are troublesome weeds that are economically damaging to seve

181 t a rapid rise in the populations of several troublesome weeds that are tolerant or resistant to herb

182 on may lead to new methods of managing these troublesome weeds.

183 nt controlled wheeze (13.1%), and persistent troublesome wheeze (PTW; 3.2%).

184 ed a novel group of children with persistent troublesome wheezing, who have markedly different outcom

185 This limitation is particularly troublesome when evaluating grasses, whose members repre

186 The freeloader problem has been particularly troublesome when groups consist of nonrelatives, and no

187 This would be especially troublesome when targets other than those corresponding

188 xpectations of enzyme performance and can be troublesome when used to select among different variants

189 reciprocal translocations and inversions, is troublesome, which is particularly detrimental in oncolo

190 hich is usually problem-free, is found to be troublesome with methylenedioxy substituent aromatics.

191 The troublesome xanthone carbonyl was protected as a butylen