ライフサイエンスコーパス: tubal

1 Macaques developing gross tubal adhesions after the first chlamydial inoculation w

2 or relative resistance to rapid formation of tubal adhesions is correlated with expression of MHC cla

3 vely associated with good perinatal outcome; tubal (adjusted OR, 0.72 [95% CI, 0.60-0.86]) or uterine

4 rectomy (RRSO) lowers mortality from ovarian/tubal and breast cancers among BRCA1/2 mutation carriers

5 These multicystic tubal and intrauterine tumors histologically resembled a

6 OR-PAM can help distinguish the severity of tubal and ovarian pathologies.

7 ng the initial surgery because of persistent tubal bleeding.

8 R = 1.52, 95% CI: 1.23, 1.87; P < 0.001) and tubal blockage (RR = 1.83, 95% CI: 1.20, 2.77; P = 0.005

9 y, particularly from ovulation disorders and tubal blockage, is associated with an increased GDM risk

10 There were 49 patients (10.9%) with cornual tubal blockage, while 57 patients (12.7%) had perifimbri

11 primary outcome was death due to ovarian or tubal cancer by June 30, 2020.

12 No significant reduction in ovarian and tubal cancer deaths was observed in the MMS (p=0.58) or

13 ing did not significantly reduce ovarian and tubal cancer deaths, general population screening cannot

14 Cediranib has activity in recurrent EOC, tubal cancer, and peritoneal cancer with predictable tox

15 ecisions among women at high risk of ovarian/tubal cancer.

16 3 had primary invasive epithelial ovarian or tubal cancers (iEOCs).

17 creening groups for both primary ovarian and tubal cancers as well as primary epithelial invasive ova

18 redictive values for all primary ovarian and tubal cancers were 89.4%, 99.8%, and 43.3% for MMS, and

19 42 (MMS) and 45 (USS) primary ovarian and tubal cancers were detected, including 28 borderline tum

20 For primary invasive epithelial ovarian and tubal cancers, the sensitivity, specificity, and positiv

21 l as primary epithelial invasive ovarian and tubal cancers.

22 y-naive patients with ovarian peritoneal and tubal carcinoma to establish a maximum-tolerated dose (M

23 Women sterilized by bipolar tubal coagulation before the age of 30 years had a proba

24 Antibody levels increased with tubal damage severity.

25 essing rates of symptomatic PID, subclinical tubal damage, and long-term reproductive sequelae after

26 s infection; better tools to measure PID and tubal damage; and studies on the natural history of repe

27 overcome the barriers to fertility caused by tubal disease and low sperm count, but little progress h

28 ry dysfunction, male factor infertility, and tubal disease.

29 Tubal ectopic pregnancies can cause substantial morbidit

30 methotrexate for the treatment of women with tubal ectopic pregnancies is now common practice.

31 We studied 350 women with tubal ectopic pregnancies who were treated with methotre

32 Among women with tubal ectopic pregnancies, a high serum chorionic gonado

33 Tubal ectopic pregnancy (EP) is the most common cause of

34 matis and smoking are major risk factors for tubal ectopic pregnancy (EP), but the underlying mechani

35 Tubal ectopic pregnancy can be surgically treated by sal

36 Participants diagnosed with tubal ectopic pregnancy were administered a single dose

37 In women with a tubal ectopic pregnancy, adding oral gefitinib to parent

38 trexate, versus methotrexate alone, to treat tubal ectopic pregnancy.

39 iage, pregnancy of unknown location (PUL) or tubal EP (tEP).

40 t was undetectable in morphologically normal tubal epithelia, including those with TP53 mutations.

41 ing - initiated by C. muridarum infection of tubal epithelial cells (serving as the first hit) - into

42 n suppressed the growth of IGFBP2-expressing tubal epithelial cells via inactivation of the AKT pathw

43 e missegregation was induced in immortalized tubal epithelial cells, which proved acutely detrimental

44 ell states and lineage dynamics of the adult tubal epithelium (TE) remain insufficiently understood,

45 ubes (group 1) and 19 patients with complete tubal examination (group 2; sectioning and extensively e

46 In the tubal experiments (n = 80), the correlation coefficient

47 Tubal factor infertility (TFI) represents 36% of female

48 study, we examined whether the proportion of tubal factor infertility (TFI) that is attributable to C

49 o the immunopathogenic process in women with tubal factor infertility (TFI).

50 omatis proteins Pgp3 and Hsp60 in women with tubal factor infertility (TFI).

51 5]; ectopic pregnancy, AHR 0.42 [0.39-0.44]; tubal factor infertility AHR 0.29 [0.25-0.33]).

52 ory disease (PID) is a leading cause of both tubal factor infertility and ectopic pregnancy.

53 nflammation or damage, ectopic pregnancy, or tubal factor infertility and no studies addressing the e

54 h anal anastomosis (IPAA) is associated with tubal factor infertility in female patients.

55 f pelvic inflammatory disease and subsequent tubal factor infertility in US women.

56 nd transmission and are the leading cause of tubal factor infertility in women.

57 inflammatory disease, ectopic pregnancy and tubal factor infertility resulting from genital chlamydi

58 inflammatory disease, ectopic pregnancy, and tubal factor infertility) following chlamydia infection

59 tory disease, 0.6%; ectopic pregnancy, 0.2%; tubal factor infertility, 0.1%).

60 7]; ectopic pregnancy, AHR 1.31 [1.25-1.38]; tubal factor infertility, AHR 1.37 [1.24-1.52]) and 60%

61 mmatory disease, and possibly preterm birth, tubal factor infertility, and ectopic pregnancy in women

62 vic inflammatory disease, ectopic pregnancy, tubal factor infertility, and preterm birth.

63 ions such as pelvic inflammatory disease and tubal factor infertility, but it is unclear why some wom

64 pelvic inflammatory disease, cervicitis, and tubal factor infertility.

65 tory diseases, such as blinding trachoma and tubal factor infertility.

66 T, including pelvic inflammatory disease and tubal factor infertility.

67 nfection include fallopian tube fibrosis and tubal factor infertility.

68 inflammatory disease, ectopic pregnancy, and tubal factor infertility.

69 inflammatory disease, ectopic pregnancy, or tubal factor infertility.

70 itis, pelvic inflammatory disease (PID), and tubal factor infertility.

71 le factor infertility or untreated bilateral tubal factor.

72 uct inflammation, are attenuated in inducing tubal fibrosis and are no longer able to colonize the ga

73 13, are essential for C. muridarum to induce tubal fibrosis; this may be induced by the gastrointesti

74 helium and the post-ovulatory attenuation of tubal fluid flow is dysregulated in Adgrd1-deficient mic

75 al ciliary action and the force of adovarial tubal fluid flow, and in wild-type oviducts, fluid flow

76 dditional insights into the role of elevated tubal fluid viscosity in promoting ciliation and coordin

77 On T1-weighted images, hyperintense tubal fluid was significantly correlated with the presen

78 in situ hybridization evidence of persistent tubal infection was significantly more frequent among an

79 Hydrosalpinx is a pathological hallmark of tubal infertility associated with chlamydial infection.

80 in hydrosalpinx, a pathological hallmark for tubal infertility in women infected with C. trachomatis.

81 Tubal infertility was not associated with the duration o

82 a trachomatis, a leading infectious cause of tubal infertility, induces upper genital tract pathology

83 mice has been used as a surrogate marker for tubal infertility, the medical relevance of nontubal pat

84 n women's upper genital tracts, resulting in tubal infertility.

85 nger in use, suggested that they might cause tubal infertility.

86 indicates no important effect of IUD use on tubal infertility.

87 causes pelvic inflammatory disease (PID) and tubal infertility.

88 lly leading to severe complications, such as tubal infertility.

89 women for 10 years for ectopic pregnancy and tubal infertility; our findings suggest both infections

90 better natural history data on the timing of tubal inflammation and damage after C. trachomatis infec

91 effect of chlamydia screening on subclinical tubal inflammation or damage, ectopic pregnancy, or tuba

92 id to chlamydial ascension and activation of tubal inflammation, we delivered plasmid-free C. muridar

93 n, and phagocytosis; pathways that may drive tubal injury.

94 sions rapidly, within 2 weeks after a single tubal inoculation with Chlamydia trachomatis, while in o

95 re not observed until 2 weeks after a second tubal inoculation.

96 Serous tubal intra-epithelial carcinoma (STIC) lesions are the

97 yet clarified, but may be related to serous tubal intraepithelial carcinoma (STIC), the postulated o

98 arian, tubal, peritoneal cancers, and serous tubal intraepithelial carcinoma (STIC), were collected f

99 nd Tp53 mutation in Pax8 + FTE caused Serous Tubal Intraepithelial Carcinoma (STIC), which metastasiz

100 ncurrent precursor lesions, including serous tubal intraepithelial carcinoma (STIC), with genetic het

101 epithelium through a precursor stage, serous tubal intraepithelial carcinoma (STIC).

102 llopian tube, which first develops as serous tubal intraepithelial carcinoma (STIC).

103 Serous tubal intraepithelial carcinoma (STIC; stage 0) has been

104 epithelial cells and also establishes serous tubal intraepithelial carcinoma as the precursor lesion

105 s during neoplastic transformation of serous tubal intraepithelial carcinoma lesions (STIC) into high

106 early fallopian tube lesions, called serous tubal intraepithelial carcinoma.

107 e fallopian tube epithelium (FTE) and serous tubal intraepithelial carcinomas (STIC) as the tissue of

108 early p53 signatures to latter-stage, serous tubal intraepithelial carcinomas (STICs) is characterize

109 llopian tube lesions (p53 signatures, serous tubal intraepithelial carcinomas (STICs), and fallopian

110 g from small precursor lesions called serous tubal intraepithelial carcinomas (TICs, or more specific

111 remain cancer-prone and give rise to serous tubal intraepithelial carcinomas and overt HGSC.

112 for sperm migration to and through the utero-tubal junction (UTJ), and they are divided into ADAM3-de

113 demonstrate that spermatozoa past the utero-tubal junction possess the intact CatSper1 signals.

114 lated to 1 case of UEC, and NGS of the other tubal lesion diagnosed as a STIC unexpectedly supported

115 In five of five cases, the peritoneal and tubal lesion shared an identical p53 mutation.

116 ques (Macaca fuscata) were ovariectomized or tubal-ligated (n=5/group) and returned to their natal tr

117 d 32 080 who underwent hysterectomy alone or tubal ligation (mean [SD] age, 38.2 [7.9] years; median

118 6% (p < 0.001) for noncarriers), history of tubal ligation (odds ratio = 0.68 (95% CI: 0.25, 1.90) f

119 endectomies (eight), liver biopsies (three), tubal ligation (one), and cholecystectomies (three).

120 Tubal ligation (RR = 0.66, 95% CI: 0.50, 0.87) was assoc

121 r relations across racial/ethnic groups, but tubal ligation and family history of breast or ovarian c

122 No interactions between ever having had a tubal ligation and other covariates were observed.

123 ere analyzed to examine the relation between tubal ligation and ovarian cancer mortality in a large p

124 s, transgastric liver biopsies, transgastric tubal ligation and transvaginal cholecystectomy without

125 Our results suggest IUD use and tubal ligation are not associated with higher circulatin

126 Standard outpatient procedures such as tubal ligation are now being joined by ambulatory laparo

127 a low risk for pregnancy due to factors like tubal ligation or abstinence.

128 ulting in permanent contraception (bilateral tubal ligation or hysterectomy without concurrent salpin

129 These data suggest that tubal ligation reduces the risk of fatal ovarian cancer.

130 femoral) and then omental fat biopsy during tubal ligation surgery.

131 Tubal ligation was significantly associated with a decre

132 ilarly, age at menopause, endometriosis, and tubal ligation were only associated with endometrioid an

133 es at the time of hysterectomy or instead of tubal ligation while leaving ovaries intact.

134 ined the association of OC use, IUD use, and tubal ligation with plasma levels of C-reactive protein

135 The inverse association for tubal ligation with risk was most pronounced for Native

136 pian tubes during hysterectomy or instead of tubal ligation without removal of ovaries, is recommende

137 er, nulliparity, oral contraceptive use, and tubal ligation) and by number of risk factors (0, 1, and

138 or a control surgery (hysterectomy alone or tubal ligation) between 2008 and 2017, with follow-up un

139 ered for permanent contraception (in lieu of tubal ligation) or ovarian cancer prevention (performed

140 actors of pregnancy, oral contraceptive use, tubal ligation, and body mass index.

141 sely associated with oral contraceptive use, tubal ligation, and childbearing.

142 d experience pregnancy (ie, not pregnant, no tubal ligation, and not infertile).

143 ions associated with oral contraceptive use, tubal ligation, and parity.

144 ved for oral contraceptive (OC) use, parity, tubal ligation, and smoking.

145 btained from 37 women undergoing surgery for tubal ligation, ectopic pregnancy, or other gynecologic

146 cancer, duration of oral contraception use, tubal ligation, gravidity, education, and site.

147 Furthermore, tubal ligation, intrauterine device use, and infertility

148 Several gynecologic procedures including tubal ligation, oophorectomy, and partial hysterectomy h

149 Attributable fractions associated with tubal ligation, oral contraceptive use, and obesity were

150 f other, less studied contraceptive methods (tubal ligation, rhythm method, diaphragm, condoms, intra

151 e the most strongly related to pregnancy and tubal ligation, while clear cell tumors were the only ty

152 ory, inflammation, reproductive factors, and tubal ligation-modulate the risk of ovarian cancer.

153 e in part to oral contraceptive (OC) use and tubal ligation.

154 ctomy in the retrospective cohort, 241 had a tubal ligation/hysterectomy (54.2%) and 204 had other ab

155 The existence of a post-tubal-ligation syndrome of menstrual abnormalities has b

156 ase patients) and from 0 of 44 women seeking tubal ligations (the control subjects) at Kenyatta Natio

157 ator for breast-feeding, and availability of tubal ligations); and (3) clinical outcomes, including s

158 f 17 to 55 years (mean 29 years) including 9 tubal ligations, 3 neurosurgeries, 3 cholecystectomies,

159 Embryo transit involves a valve-like tubal-locking phenomenon that temporarily arrests oocyte

160 tubal PROKR1, leading to alterations in the tubal microenvironment that could predispose to EP.

161 eased tubal PROKR2, thereby predisposing the tubal microenvironment to ectopic implantation.

162 proliferation-quiescent, and postmenopausal tubal microenvironment.

163 e contractility (SMC) and alterations in the tubal microenvironment.

164 ggesting serous malignancy originates in the tubal mucosa but grows preferentially at a remote perito

165 Twenty-four women with tubal obstruction after ligation reversal surgery underw

166 en with primary infertility who did not have tubal occlusion (infertile controls) and 584 primigravid

167 is not associated with an increased risk of tubal occlusion among nulligravid women whereas infectio

168 In analyses involving the women with tubal occlusion and the infertile controls, the odds rat

169 d the infertile controls, the odds ratio for tubal occlusion associated with the previous use of a co

170 d 358 women with primary infertility who had tubal occlusion documented by hysterosalpingography, as

171 h hydrosalpinx and nine patients (2.0%) with tubal occlusion.

172 between the previous use of a copper IUD and tubal occlusion.

173 infected animals, suggesting the presence of tubal occlusion.

174 R 15.1-17.3), 2055 women were diagnosed with tubal or ovarian cancer: 522 (1.0%) of 50 625 in the MMS

175 ions to reduce the risk for breast, ovarian, tubal, or peritoneal cancer in women with potentially ha

176 rsonal or family history of breast, ovarian, tubal, or peritoneal cancer or who have an ancestry asso

177 ith a previous diagnosis of breast, ovarian, tubal, or peritoneal cancer who have completed treatment

178 ho have family members with breast, ovarian, tubal, or peritoneal cancer with 1 of several screening

179 recurrent or persistent epithelial ovarian, tubal, or peritoneal carcinoma, measurable or detectable

180 ction) area between the OSE, mesothelium and tubal (oviductal) epithelium, as a previously unrecogniz

181 review discusses the recent advances in this tubal paradigm and its biological and clinical implicati

182 infected IL-10(-/-) mice were protected from tubal pathologies and infertility, whereas WT (IL-10(+/+

183 in rapid microbial clearance, which prevents tubal pathologies during infection.

184 chlamydial infection and the development of tubal pathologies.

185 cts mice, can induce hydrosalpinx in mice, a tubal pathology also seen in women infected with C. trac

186 llopian tubes and subsequent immune-mediated tubal pathology in females.

187 vulation induction only or IVF for bilateral tubal pathology were excluded.

188 nding the etiology of immune system-mediated tubal pathology, we evaluated the regional recruitment o

189 earance of chlamydiae and the development of tubal pathology.

190 tory infiltrate that may also participate in tubal pathology.

191 ir sensitivity and specificity for detecting tubal pathology.

192 varian and tubal tissues, free from ovarian, tubal, peritoneal cancers, and serous tubal intraepithel

193 ove OS among patients with newly diagnosed O/tubal/peritoneal cancer, but may modestly increase PFS.

194 epithelial ovarian cancer (EOC), one of the tubal/peritoneal cancers collectively referred to as pel

195 Invasive or intraepithelial ovarian/tubal/peritoneal neoplasms were detected in 25 (2.6%) of

196 ) early spontaneous abortions, and two (15%) tubal pregnancies.

197 and primary amenorrhea, but with spontaneous tubal pregnancies.

198 hypertension (4.4%), proteinuria (4.4%), and tubal pregnancy (2.2%).

199 and older with a laparoscopically confirmed tubal pregnancy and a healthy contralateral tube were ra

200 In women with a tubal pregnancy and a healthy contralateral tube, salpin

201 sociated with infertility due to uterine and tubal problems, with relative risks of 7.7 (95% CI: 2.3,

202 f infertility is primarily due to uterine or tubal problems.

203 smoking predisposes women to EP by altering tubal PROKR1 expression.

204 rgets human FTs via nAChRalpha-7 to increase tubal PROKR1, leading to alterations in the tubal microe

205 FkappaB by C. trachomatis leads to increased tubal PROKR2, thereby predisposing the tubal microenviro

206 rgery underwent selective salpingography and tubal recanalization.

207 , as a second hit, to transmucosally convert tubal repairing - initiated by C. muridarum infection of

208 us, MMP-9 in particular could play a role in tubal scarring in response to gonococcal infection.

209 ade serous tumors can originate in fallopian tubal secretory epithelial cells and also establishes se

210 Contemporary IUDs rival tubal sterilisation in efficacy and are much safer than

211 ibroids were first visualized at the time of tubal sterilization (1978-1979 or 1985-1987) or who repo

212 patients aged 18 to 49 years who underwent a tubal sterilization after childbirth (postpartum sterili

213 ad Medicaid insurance and were contemplating tubal sterilization after delivery.

214 A total of 9514 women who underwent tubal sterilization and 573 women whose partners underwe

215 a-analysis also found no association between tubal sterilization and breast cancer risk (odds ratio =

216 We investigated the association between tubal sterilization and breast cancer risk among 77,249

217 summary estimate for the association between tubal sterilization and breast cancer risk.

218 Women who have undergone tubal sterilization are no more likely than other women

219 lity of ectopic pregnancy for all methods of tubal sterilization combined was 7.3 per 1000 procedures

220 MyDecision/MiDecision significantly improved tubal sterilization decision-making quality compared wit

221 Tubal sterilization does not appear to be associated wit

222 A history of tubal sterilization does not rule out the possibility of

223 vided data on ovariectomy, hysterectomy, and tubal sterilization during in-person interviews.

224 ngectomy) in lieu of conventional methods of tubal sterilization helps reduce ovarian cancer risk.

225 Tubal sterilization is a common form of contraception in

226 Tubal sterilization is a common gynecological procedure

227 Tubal sterilization is an increasingly common method of

228 Tubal sterilization is common, especially among individu

229 he intervention arm answering correctly that tubal sterilization is not easily reversible (90.1% vs 3

230 Specifically, tubal sterilization is unassociated with breast cancer r

231 urnal, Gaudet et al. argue successfully that tubal sterilization is unassociated with breast cancer r

232 to the decision aid had significantly higher tubal sterilization knowledge (mean [SD] proportion of q

233 The co-primary outcomes were tubal sterilization knowledge and decisional conflict re

234 Several studies suggest that tubal sterilization may decrease the risk of ovarian can

235 on with breast cancer risk was observed with tubal sterilization only or partial ovariectomy without

236 written, audio, and video information about tubal sterilization procedures; an interactive table com

237 es was greater among women who had undergone tubal sterilization than among women who had not.

238 In the CPS-II Nutrition Cohort, tubal sterilization was not associated with breast cance

239 A total of 10,685 women undergoing tubal sterilization were followed in a multicenter, pros

240 Associations stratified by year of tubal sterilization, age, and time since surgery were al

241 for uterine fibroids among women undergoing tubal sterilization.

242 women who had undergone the common types of tubal sterilization.

243 Tubal swabs remained positive in 3 placebo-, 1 doxycycli

244 Ovarian and tubal tissues, free from ovarian, tubal, peritoneal canc

245 We propose that ligation of tubal TLR2 and activation of NFkappaB by C. trachomatis

246 nce of a dilated fallopian tube or thickened tubal wall and mucosal folds and the signal intensity of

247 and unifocal, with variable invasion of the tubal wall.