ライフサイエンスコーパス: tuberculous

1 ie Kinder der Tuberkuloesen (Children of the Tuberculous).

2 illi in the lung and spleen after a virulent tuberculous aerosol challenge.

3 fluid and plasma to differentially diagnose tuberculous and malignant pleural effusion.

4 Recovery of the tuberculous and nontuberculous isolates by the Tween 80-

5 Recovery of the tuberculous and nontuberculous mycobacteria following CB

6 trument-negative MGIT cultures included both tuberculous and nontuberculous mycobacteria.

7 ell surface molecules present in several non-tuberculous and opportunistic mycobacterial species.

8 Tuberculous and postoperative infections were excluded.

9 entify and differentiate between features of tuberculous and pyogenic spondylodiscitis on MR images.

10 Mortality from pneumococcal, tuberculous, and culture-negative meningitis was high in

11 es of lymph node cells from protein-deprived tuberculous animals.

12 centrations of rifampicin, a first-line anti-tuberculous antibiotic targeting RNA polymerase.

13 Their intriguing conservation in pathogenic tuberculous bacteria and the fact that these highly immu

14 , serofibrinous, and fungoid forms), whereas tuberculous bursitis exhibited two patterns of involveme

15 ree cows, 3 Mycobacterium bovis BCG-infected tuberculous cattle, or 3 cows artificially inoculated wi

16 5B-immunized mice (305 +/- 9 days) after the tuberculous challenge was extended 102 days relative to

17 eting cells, and significant resistance to a tuberculous challenge.

18 okines in PTB individuals at the end of anti-tuberculous chemotherapy (ATT).

19 escribes a novel PPD protein present only in tuberculous complex mycobacteria.

20 contribute to the granulomatous response in tuberculous diseases.

21 of DILI were acetaminophen (35.0 %) and anti-tuberculous drugs (34.7 %).

22 hat cares for about 200 patients with active tuberculous each year.

23 t include background immunity induced by non-tuberculous environmental mycobacteria, diversity of BCG

24 In the tuberculous granulation tissue surrounding caseous and l

25 ives: To ascertain the 3D shape of the human tuberculous granuloma and its spatial relationship with

26 sential for maintaining the structure of the tuberculous granuloma and may regulate the granulomatous

27 Thus, TNF is not required for tuberculous granuloma formation, but maintains granuloma

28 t and consequences of vascularization of the tuberculous granuloma in the zebrafish-Mycobacterium mar

29 , and IL-35-producing B cells infiltrated to tuberculous granuloma of patients with ATB.

30 TNF results in marked disorganization of the tuberculous granuloma, as demonstrated by the dissolutio

31 gs about the composition and dynamics of the tuberculous granuloma, the central host structure in myc

32 n, and are amplified and disseminated by the tuberculous granuloma.

33 cted macrophages undergoing apoptosis in the tuberculous granuloma.

34 erates macrophage recruitment to the forming tuberculous granuloma.

35 le in modulating the cellular composition of tuberculous granuloma; 2) CXCR3 impairs antimycobacteria

36 What is happening inside the tuberculous granuloma?

37 is essential for the formation of protective tuberculous granulomas and regulates the expression of o

38 he observed patterns of neutrophils in human tuberculous granulomas and the susceptibility of humans

39 Tuberculous granulomas have long been considered host-pr

40 this probe to evaluate the oxygen tension in tuberculous granulomas in four animal models of disease:

41 eity of local immunologic characteristics of tuberculous granulomas in nonhuman primates.

42 Immunity, Egen et al. present live images of tuberculous granulomas of the mouse, demonstrating the i

43 Zebrafish tuberculous granulomas undergo caseous necrosis, similar

44 e functional consequences of angiogenesis in tuberculous granulomas, and data that balanced inflammat

45 tly elevated in the inflammatory zone of the tuberculous granulomas, and in the nongranulomatous pneu

46 le in both the construction and breakdown of tuberculous granulomas, our results suggest that TDM may

47 rious conditions postulated to be operant in tuberculous granulomas, suggesting that their granuloma-

48 Although tuberculous granulomas, which are composed of infected m

49 In contrast to mammalian tuberculous granulomas, zebrafish lesions contain few ly

50 ing persistence in mycobacteria-which models tuberculous granulomas-are partly determined by a mechan

51 s undergo caseous necrosis, similar to human tuberculous granulomas.

52 he functional capacity of these cells within tuberculous granulomas.

53 d NO are present in specialized areas of the tuberculous granulomas; their precise role in human TB r

54 Since apoptosis is observed in tuberculous granulomata, we investigated the molecular m

55 Malnourished, tuberculous guinea pigs harbored only 20 and 60% of the

56 Hepatobiliary tuberculosis includes miliary, tuberculous hepatitis or localized forms.

57 p insights into different layers of the anti-tuberculous immune response and the identification of im

58 individuals who had radiographic evidence of tuberculous infection (i.e., calcified granulomas) were

59 the contributions of reactivation of latent tuberculous infection (LTBI) and the progression of new

60 tor from such countries increase the risk of tuberculous infection among young children.

61 veillance data concerning groups at risk for tuberculous infection and allows recommended public heal

62 mportant measures for interpreting trends in tuberculous infection and disease but are complicated by

63 itis C and graft failure without evidence of tuberculous infection at death.

64 the age-stratified prevalence difference of tuberculous infection between case and control networks,

65 Reactivation of latent tuberculous infection by aminoguanidine treatment was co

66 t RNI are required for the control of murine tuberculous infection caused by both laboratory and clin

67 The annual risk of tuberculous infection for white men in the United States

68 To assess whether there is increased risk of tuberculous infection in children who traveled to or had

69 The outcome of tuberculous infection in mice deficient in the CD11b sub

70 nd incentive approaches, treatment of latent tuberculous infection in those HIV-seropositive, and scr

71 tion-based national data are available about tuberculous infection in young people from such backgrou

72 is not useful in screening for asymptomatic tuberculous infection or for diagnosing active tuberculo

73 A case of tuberculous infection was defined as a positive tubercul

74 The incidence of tuberculous infection was measured in a cohort of 8809 c

75 mechanisms involved in the control of latent tuberculous infection were examined using two murine exp

76 In an at-risk population for tuberculous infection who were either tuberculin skin te

77 are important for containing and restricting tuberculous infection, and suggest that malnutrition-ind

78 In a setting with a high risk of tuberculous infection, HIV-1 increases the risk of recur

79 The secondary outcome was the incidence of tuberculous infection, measured using tuberculin skin te

80 importance of Th1 immunity in the control of tuberculous infection, the results of the present study

81 p with a high prevalence of tuberculosis and tuberculous infection, these efforts remain an important

82 cines in cattle, a natural target species of tuberculous infection.

83 morphological features with persistent human tuberculous infection.

84 city of the test depended on the presence of tuberculous infection.

85 phage activation in controlling a persistent tuberculous infection.

86 ar cells from persons across the spectrum of tuberculous infection.

87 ity has a high positive predictive value for tuberculous infection.

88 tified by country and baseline prevalence of tuberculous infection: group 1 strengthened tuberculosis

89 critical to the pathogenesis of progressive tuberculous infections in animal models.

90 on disease progression in mice with chronic tuberculous infections.

91 tral role that CD4 cells play in controlling tuberculous infections.

92 the host in both persistent and reactivated tuberculous infections.

93 this therapeutic approach markedly inhibits tuberculous inflammation in lungs, increases the surviva

94 smigration across pleural mesothelium during tuberculous inflammation was investigated.

95 Recovery of the tuberculous isolates following NALC-NaOH processing aver

96 are as follows: growth of MDR TB from an old tuberculous lesion in a patient who was never treated fo

97 Liquefaction of solid caseous tuberculous lesions and the subsequent cavity formation

98 Paradoxical expansion of tuberculous lesions during therapy should be treated wit

99 PSMA PET-positive lung cancers as well as in tuberculous lesions from our histologic database.

100 ism, drug penetration, and immune control of tuberculous lesions has the potential to facilitate drug

101 Advances in monitoring tuberculous lesions have utilized the common glucoside [

102 both macrophage physiology and the nature of tuberculous lesions in man and animals suggests that hyp

103 The 2 tuberculous lesions showed an SUVmax of 7.8 and 2.5.

104 lymphocytes and immature macrophages in the tuberculous lung are basic to the local immunopathogenes

105 found in the affected but not the unaffected tuberculous lung compared with healthy controls.

106 ons associated with B cell-rich foci seen in tuberculous lung granulomas.

107 F-alpha) was also significantly increased in tuberculous lungs and was principally localized to the n

108 the 3D microanatomical environment of human tuberculous lungs by using micro computed tomography, hi

109 e in controlling TB, its expression in human tuberculous lungs has not been systematically characteri

110 Tuberculous lymphadenitis (TBL) is the most common form

111 inal failure, mutations in the NOD2 gene and tuberculous lymphadenitis has not been described before.

112 Tuberculous lymphadenitis is the main manifestation of e

113 evidence proved or was highly suggestive for tuberculous lymphadenitis.

114 in 2002 will have prevented 29,729 cases of tuberculous meningitis (5th-95th centiles, 24,063-36,192

115 e cerebrospinal fluid (CSF) of patients with tuberculous meningitis (TBM) are associated with TBM-IRI

116 Mortality and morbidity from tuberculous meningitis (TBM) are common, primarily due t

117 Point-of-care tests for tuberculous meningitis (TBM) are needed.

118 Pretreatment predictors of death from tuberculous meningitis (TBM) are well established, but w

119 a fully automated PCR assay, as the initial tuberculous meningitis (TBM) diagnostic test.

120 Murine models of tuberculous meningitis (TBM) have not reflected the seve

121 ome, and prognostic factors in children with tuberculous meningitis (TBM) in Europe are limited.

122 Tuberculous meningitis (TBM) is a devastating form of tu

123 Tuberculous meningitis (TBM) is a devastating infection

124 Tuberculous meningitis (TBM) is a frequent cause of meni

125 Tuberculous meningitis (TBM) is a severe complication of

126 The diagnosis of tuberculous meningitis (TBM) is difficult and poses a si

127 Drug-resistant tuberculous meningitis (TBM) is difficult to diagnose an

128 Tuberculous meningitis (TBM) is the most devastating for

129 Tuberculous meningitis (TBM) is the most lethal form of

130 Tuberculous meningitis (TBM) is the most severe form of

131 Tuberculous meningitis (TBM) is the most severe form of

132 Tuberculous meningitis (TBM) leads to death or disabilit

133 The delayed diagnosis of tuberculous meningitis (TBM) leads to poor outcomes, yet

134 ulosis load in the brain of individuals with tuberculous meningitis (TBM) may reflect the host's abil

135 Neurological complications of tuberculous meningitis (TBM) often lead to raised intrac

136 noassay) in cerebral spinal fluid (CSF) from tuberculous meningitis (TBM) patients.

137 Tuberculous meningitis (TBM) remains a major cause of de

138 Mortality from tuberculous meningitis (TBM) remains around 30%, with mo

139 Tuberculous meningitis (TBM) research is hampered by low

140 Early diagnosis and treatment of tuberculous meningitis (TBM) saves lives, but current la

141 a national molecular diagnostic service for tuberculous meningitis (TBM) using an in-house IS6110-ta

142 ibute to the high morbidity and mortality of tuberculous meningitis (TBM), but the link between infla

143 s reported as a common complication in adult tuberculous meningitis (TBM), yet few studies have syste

144 udy of HIV-infected, ART-naive patients with tuberculous meningitis (TBM).

145 l fluid (CSF) inflammation, and outcome from tuberculous meningitis (TBM).

146 e available on their use in the diagnosis of tuberculous meningitis (TBM).

147 one is recommended as adjunctive therapy for tuberculous meningitis (TBM).

148 flammatory therapies may improve outcomes in tuberculous meningitis (TBM).

149 High-dose rifampicin may improve outcomes of tuberculous meningitis (TBM).

150 is evaluated in novel treatment regimens for tuberculous meningitis (TBM).

151 Tuberculous meningitis (TM) is difficult to diagnose and

152 diagnosis; the rest had probable or possible tuberculous meningitis according to published criteria.

153 We calculated the number of tuberculous meningitis and miliary tuberculosis cases th

154 consistently high efficacy against childhood tuberculous meningitis and miliary tuberculosis, but var

155 The polymorphisms were associated with both tuberculous meningitis and pulmonary tuberculosis and we

156 lware discusses the challenges of diagnosing tuberculous meningitis and the implications of the study

157 ants were classified as probable or definite tuberculous meningitis by uniform case definition, exclu

158 Consequently, differences in tuberculous meningitis characteristics across the lifesp

159 rospinal fluid of humans with HIV-associated tuberculous meningitis commonly express surface OX40 pro

160 87; 16 of 23 cases) for probable or definite tuberculous meningitis compared with 43% (23-66; 10/23)

161 uman immunodeficiency virus (HIV)-associated tuberculous meningitis despite limited data supporting t

162 6 in cerebrospinal fluid leukocytes improves tuberculous meningitis diagnosis.

163 Tuberculous meningitis disproportionately affects young

164 Children with tuberculous meningitis had baseline magnetic resonance i

165 Despite treatment, childhood tuberculous meningitis has very poor outcomes.

166 00) children younger than 15 years developed tuberculous meningitis in 2019.

167 With composite standard, we detected tuberculous meningitis in 22 (17%) of 129 participants.

168 Laboratory evidence for tuberculous meningitis is difficult to acquire due to th

169 Tuberculous meningitis is especially common in young chi

170 ing the care of critically ill patients with tuberculous meningitis is poor and many patients do not

171 Tuberculous meningitis is the most severe form of tuberc

172 design in Vietnam with cases that had either tuberculous meningitis or pulmonary tuberculosis.

173 Advances in the field of tuberculous meningitis predominantly focus on diagnosis,

174 logical differences adults and children with tuberculous meningitis receive similar treatment and are

175 search that were drafted at an international tuberculous meningitis research meeting organized by the

176 ematic review and meta-analysis of childhood tuberculous meningitis studies published up to Oct 12, 2

177 and low threshold for empirical treatment of tuberculous meningitis suspects.

178 ION: Xpert Ultra detected significantly more tuberculous meningitis than did either Xpert or culture.

179 higher rate of survival among patients with tuberculous meningitis than standard treatment.

180 apeutic, and neurosurgical interventions for tuberculous meningitis that will improve morbidity and m

181 Here, we use a rabbit model of tuberculous meningitis to evaluate the severity of disea

182 Tuberculous meningitis was observed in animals given M.

183 o hundred and eighty patients with suspected tuberculous meningitis were enrolled.

184 usly reported that rabbits with experimental tuberculous meningitis were protected from death by a co

185 fluid specimens from patients with suspected tuberculous meningitis were stained by conventional Zieh

186 infected adults with a clinical diagnosis of tuberculous meningitis who were admitted to one of two V

187 Among the 24 000 children with tuberculous meningitis, 16 100 (14 900-17 300) were esti

188 The pathogenesis of tuberculous meningitis, a devastating complication of tu

189 Among HIV-positive adults with tuberculous meningitis, adjunctive dexamethasone, as com

190 coccal meningitis, 48 with culture-confirmed tuberculous meningitis, and 2900 with culture-negative C

191 gitis, 46% (22 of 48) and 56% (27 of 48) for tuberculous meningitis, and 41% (1181 of 2900) and 49% (

192 ents with culture-confirmed pneumococcal and tuberculous meningitis, and all patients with culture-ne

193 t approaches to prevent, diagnose, and treat tuberculous meningitis, and there are still too few answ

194 le tuberculous meningitis, three as possible tuberculous meningitis, and two as not tuberculous menin

195 d the prevalence of cryptococcal meningitis, tuberculous meningitis, bacterial meningitis, and cerebr

196 gher rifampicin doses may improve outcome of tuberculous meningitis, but the desirable exposure and n

197 Among persons with tuberculous meningitis, no evidence of beneficial effect

198 hyponatraemia, which frequently accompanies tuberculous meningitis, remain to be elucidated.

199 ds are recommended as adjunctive therapy for tuberculous meningitis, the mechanism underlying their b

200 In tuberculous meningitis, the polymorphism is associated w

201 se eight, three were categorised as probable tuberculous meningitis, three as possible tuberculous me

202 Using a rabbit model of tuberculous meningitis, we evaluated the protective effi

203 lity in order to identify optimal dosing for tuberculous meningitis.

204 ar stain improve the laboratory diagnosis of tuberculous meningitis.

205 or PCR (n = 2) and 11% (6/54) had confirmed tuberculous meningitis.

206 disease severity and outcome in adults with tuberculous meningitis.

207 HIV and 428 (85.8%) had definite or probable tuberculous meningitis.

208 ring a hospital admission, and in those with tuberculous meningitis.

209 ical impact of dexamethasone, as observed in tuberculous meningitis.

210 he new Xpert MTB/RIF Ultra (Xpert Ultra) for tuberculous meningitis.

211 as the initial diagnostic test for suspected tuberculous meningitis.

212 rt MTB/RIF as initial diagnostic testing for tuberculous meningitis.

213 sible tuberculous meningitis, and two as not tuberculous meningitis.

214 estions concerning the optimal management of tuberculous meningitis; these studies also form a platfo

215 imated to be in children who did not receive tuberculous-meningitis treatment.

216 ct of PDE-Is on the duration of treatment in tuberculous mice.

217 cilomilast accelerated the time to death in tuberculous mice.

218 finding that sequences representative of non-tuberculous mycobacteria (NTM) and other opportunistic h

219 Non-tuberculous mycobacteria (NTM) are a large family of aci

220 drug-resistant tuberculosis (MDR-TB) and non-tuberculous mycobacteria (NTM) infection, which can be u

221 The frequency of isolation of non-tuberculous mycobacteria (NTM) species from respiratory

222 Humans are regularly exposed to non-tuberculous mycobacteria (NTM) that live in soil and wat

223 teria, the four-gene module occurred only in tuberculous mycobacteria and was required for intramacro

224 Non-tuberculous mycobacteria cause a broad range of clinical

225 itive diagnostic assays for the detection of tuberculous mycobacteria in elephants are lacking.

226 ence of tuberculosis and infections with non-tuberculous mycobacteria in human populations, but the m

227 ie severe disease caused by environmental or tuberculous mycobacteria, and other intra-macrophagic mi

228 Despite concerns about non-tuberculous mycobacteria, especially Mycobacterium absce

229 s mycobacterial populations with various non-tuberculous mycobacteria, including members of the Mycob

230 cid biosynthesis, is very potent against the tuberculous mycobacteria.

231 Pulmonary non-tuberculous mycobacterial (NTM) disease epidemiology in

232 Furthermore, isolated pulmonary non-tuberculous mycobacterial infection has been increasing

233 to confer susceptibility to disseminated non-tuberculous mycobacterial infection.

234 Cultures suggestive of Non-tuberculous mycobacterial infections (NTM) were sub-cult

235 actors underlying localised and systemic non-tuberculous mycobacterial infections.

236 th respiratory isolates met criteria for non-tuberculous mycobacterial pulmonary disease (NTM-PD).

237 ng infected with the multidrug-resistant non-tuberculous mycobacterium (NTM) Mycobacterium abscessus,

238 ium abscessus (Mab) is a rapidly growing non-tuberculous mycobacterium (NTM) that causes a wide range

239 s show promise as therapeutic agents for non-tuberculous mycobacterium infections.

240 scessus (Mab) is a highly drug-resistant non-tuberculous mycobacterium that presents major treatment

241 which has a smooth colony morphology, is the tuberculous organism retaining the most genetic traits f

242 He found that children of tuberculous parents had higher mortality rates and lower

243 control tuberculosis, leprosy and other non-tuberculous pathogens.

244 To identify host cell genes involved in tuberculous pathology, we screened macrophage cDNA libra

245 d IL-1 beta, was not up-regulated in PBMC of tuberculous patients.

246 , NF-kappa B was activated in monocytes from tuberculous patients.

247 14 of 28 specimens (50%) from patients with tuberculous pericarditis (P > 0.15).

248 fluid (PF) lipoarabinomannan (LAM) assays in tuberculous pericarditis (TBP).

249 Sixteen of the 20 patients had tuberculous pericarditis and 4 patients had other diagno

250 30 of 43 specimens (70%) from patients with tuberculous pericarditis and by PCR in 14 of 28 specimen

251 ture and histopathology for the diagnosis of tuberculous pericarditis in 36 specimens of pericardial

252 Tuberculous pericarditis is associated with high morbidi

253 signed 1400 adults with definite or probable tuberculous pericarditis to either prednisolone or place

254 In patients with tuberculous pericarditis, neither prednisolone nor M. in

255 le diseases such as rheumatic heart disease, tuberculous pericarditis, or cardiomyopathy and others h

256 ndicus pranii immunotherapy in patients with tuberculous pericarditis.

257 -characterized ascitic fluid bank, including tuberculous peritonitis (n = 7), tuberculous peritonitis

258 of ascitic fluid ADA activity in diagnosing tuberculous peritonitis in a U.S. patient population.

259 , including tuberculous peritonitis (n = 7), tuberculous peritonitis in the setting of cirrhosis (n =

260 ver, ADA was only 30% sensitive in detecting tuberculous peritonitis in the setting of cirrhosis, and

261 sis, and cirrhosis was present in 59% of the tuberculous peritonitis patients in our population.

262 ivity of the ADA determination in diagnosing tuberculous peritonitis was only 58.8%, and the specific

263 Tuberculous peritonitis, although common in Third World

264 We enrolled 91 cases, including tuberculous pleural effusion (TPE, n = 50), malignant pl

265 s facilitates monocyte transmigration during tuberculous pleural inflammation.

266 tributed, being more common in patients with tuberculous pleurisy (92%) in comparison with healthy M.

267 e pleural effusion, diagnostic treatment for tuberculous pleurisy by anti-tuberculosis drugs was perf

268 Tuberculous pleurisy is a severe inflammatory response i

269 Analysis of cytokine expression during tuberculous pleurisy may lead to a better understanding

270 In tuberculous pleurisy pleural mesothelial cells are expos

271 We have used the guinea pig model of tuberculous pleurisy to examine several aspects of the i

272 by using the established guinea pig model of tuberculous pleurisy.

273 in pleural biopsy sections of patients with tuberculous pleurisy.

274 cted of benign asbestos pleural effusion and tuberculous pleurisy.

275 f pleural macrophages in the pathogenesis of tuberculous pleuritis and to monitor the response to ant

276 hages play critical roles in pathogenesis of tuberculous pleuritis, but very little is known about th

277 l mesothelial cells (PMCs) express ICAM-1 in tuberculous pleuritis.

278 reater than those of PBMC from patients with tuberculous pleuritis.

279 owing antibiotics treatment in patients with tuberculous pleuritis.

280 Tuberculous pneumonia, necrotic granulomatous lesions, a

281 t mechanisms contribute to the prevention of tuberculous reactivation.

282 ry tuberculosis compared with those with non-tuberculous respiratory tract infections.

283 o be infected, with up to 8% having external tuberculous signs, in wild populations in Northumberland

284 diagnosed with pyogenic spondylodiscitis and tuberculous spondylodiscitis allowed identification of i

285 regarding possibility to distinguish between tuberculous spondylodiscitis and pyogenic spondylodiscit

286 Prevailing features of tuberculous spondylodiscitis included: involvement of th

287 Tuberculous spondylodiscitis is characterized by the loc

288 with pyogenic spondylodiscitis, and 16 with tuberculous spondylodiscitis).

289 Transient worsening of tuberculous symptomatology and lesions following antitub

290 okine that is implicated in the formation of tuberculous (TB) granulomas and in immunity to Mycobacte

291 R imaging allowed evaluation of all forms of tuberculous tenosynovitis (hygromatous, serofibrinous, a

292 Tuberculous tenosynovitis most commonly involved the ten

293 All cases of tuberculous tenosynovitis or bursitis showed soft-tissue

294 Twelve patients had tuberculous tenosynovitis, and nine had bursitis.

295 osite reference standard of any positive CSF tuberculous test.

296 Existing anti-tuberculous therapies require long treatments and are co

297 y more accurate in identifying true-positive tuberculous uveitis cases than was T-SPOT.TB among disco

298 and the tuberculin skin test) for diagnosing tuberculous uveitis.

299 red for assessment of the efficiency of anti-tuberculous vaccines.

300 meningitis (TBM) is the most severe form of tuberculous with substantial mortality.