ライフサイエンスコーパス: tumor virus

1 tate of a GR-induced promoter (mouse mammary tumor virus).

2 oses additional oncogenic properties of this tumor virus.

3 virus (MCPyV) is a human double-stranded DNA tumor virus.

4 oma-associated herpesvirus (KSHV) is a human tumor virus.

5 ions by viruses like HIV-1 and mouse mammary tumor virus.

6 aposi's sarcoma herpesvirus (KSHV) human DNA tumor viruses.

7 milar to that of T antigens of the small DNA tumor viruses.

8 uppressor pathway in a manner similar to DNA tumor viruses.

9 so targeted by oncoproteins expressed by DNA tumor viruses.

10 frequent integration sites for mouse mammary tumor viruses.

11 as a good model for oncology study involving tumor viruses.

12 ar stomatitis, pseudocowpox, and Yaba monkey tumor viruses.

13 cts associated with infections with many DNA tumor viruses.

14 mechanisms of transformation employed by DNA tumor viruses.

15 lomaviruses are a family of nonenveloped DNA tumor viruses.

16 through the use of GEM models for human DNA tumor viruses.

17 red to mediate transformation induced by DNA tumor viruses.

18 in many cancers and is also targeted by DNA tumor viruses.

19 leosome A of the 3'-LTR of the mouse mammary tumor virus (147 bp MMTV-A).

20 genous superantigen encoded by mouse mammary tumor virus 8 (Mtv-8) by either deletion or T-cell recep

21 radioimmunoconstruct in a transgenic Nestin-tumor virus A (Ntva) mouse model of high-grade glioblast

22 he Keratin 6a (K6a) gene promoter to express tumor virus A (tva), which encodes the receptor for avia

23 ection with EnvA-pseudotyped rabies virus in tumor virus A receptor transgenic mice, indicating that

24 s for two of these viruses-the mouse mammary tumor virus (a retrovirus) and Machupo virus (an arenavi

25 Epstein-Barr virus (EBV) is a human tumor virus and a model of herpesviral latency.

26 gh-resolution structural data for this human tumor virus and demonstrate that the full capsid is requ

27 HC-I), C-type lectins, and the mouse mammary tumor virus and herpesvirus saimiri superantigens.

28 ct with the transforming oncoproteins of DNA tumor viruses and this led to rapid advances in our unde

29 s are attractive metabolic targets to combat tumors, virus and parasitic diseases but have not yet be

30 the NLRP3 inflammasome, to deregulation of a tumor virus, and 4) demonstrate that B lymphocytes from

31 lied to heterogeneous genetic samples (e.g., tumors, viruses, and genomes of organelles).

32 ffective in malignant diseases for which DNA tumor viruses are etiologic agents and that antitumor ac

33 ental effect on viral replication.IMPORTANCE Tumor viruses are known to interact with machinery respo

34 Oncoproteins from DNA tumor viruses associate with critical cellular proteins

35 olyomavirus (MCPyV) is a small, nonenveloped tumor virus associated with an aggressive form of skin c

36 oma-associated herpesvirus (KSHV) is a human tumor virus associated with several cancers.

37 seful for reconstructing fusion isoforms and tumor viruses, both of which are important in cancer res

38 key target of oncoproteins expressed by DNA tumor viruses, but RNA viruses are not known to regulate

39 erse transcriptase in retroviruses (then RNA tumor viruses) by David Baltimore and Howard Temin revol

40 initiated by an overexpressed mouse mammary tumor virus-c-myc transgene, which on its own produced p

41 o the host genome, is a critical step in DNA tumor virus carcinogenesis.

42 Human papillomaviruses (HPV) are small DNA tumor viruses causally associated with cervical cancer.

43 The study of the small DNA tumor viruses continues to provide valuable new insights

44 y, mammary tumors derived from mouse mammary tumor virus-CR-1 mice showed a dramatic reduction of Cav

45 isolated from Cav-1 null(-/-)/mouse mammary tumor virus-CR-1 transgenic animals showed enhanced moti

46 I (TGFbetaRI), either by using mouse mammary tumor virus-Cre mice or by delivering adenoviral vector

47 vivo, we created and analyzed murine mammary tumor virus-Cre-mediated FIP200 conditional knock-out (C

48 sively to our understanding of how these DNA tumor viruses directly contribute to human cancers.

49 appears to interact with naked mouse mammary tumor virus DNA somewhat differently than with chromatin

50 Previously, mouse mammary tumor virus-driven polyoma middle T-antigen (MMTV-PyV MT

51 adenomas with lung metastases [mouse mammary tumor virus-driven polyoma virus middle T oncogene (MMTV

52 d 1970s for the discovery of the first human tumor viruses--EBV, hepatitis B virus, and the papilloma

53 Many of the small DNA tumor viruses encode transforming proteins that function

54 antigen, under control of the mouse mammary tumor virus enhancer/promoter, was used to produce mamma

55 e sheep retrovirus (JSRV) and enzootic nasal tumor virus (ENTV) induce epithelial tumors in the airwa

56 Enzootic nasal tumor virus (ENTV) is related to JSRV but induces tumors

57 e sheep retrovirus (JSRV) and enzootic nasal tumor virus (ENTV), is responsible for their distinct lo

58 ession of latency protein LMP2A by the human tumor virus Epstein-Barr virus (EBV) activates phosphati

59 t virus infection, specifically by the human tumor virus Epstein-Barr virus (EBV) induces a spectrum

60 to harbor exogenous agents such as the human tumor viruses Epstein-Barr virus (EBV) and human papillo

61 The human tumor viruses Epstein-Barr virus (EBV) and Kaposi sarcom

62 The human DNA tumor viruses Epstein-Barr virus (EBV), Kaposi's sarcoma

63 In mouse mammary tumor virus-erbB2 mice treated with LGD1069, there was a

64 tumorigenic transformation in mouse mammary tumor virus-erbB2 transgenic mice.

65 oma-associated herpesvirus (KSHV) is a human tumor virus expressing latent antigens critical for path

66 ge of 4 months, 100% of female mouse mammary tumor virus-EZH2 virgin mice developed intraductal epith

67 and their application to the study of mouse tumor viruses facilitated the assembly of the first gene

68 Viruses of the DNA tumor virus family share the ability to transform verteb

69 SV40 is a DNA tumor virus found in some studies to be associated at hi

70 rs amenable to analysis is the mouse mammary tumor virus gene regulatory sequence.

71 nt to the entire 3'-end of the mouse mammary tumor virus genome, but further deletions at the 5'- or

72 Evolution of minimal DNA tumor virus' genomes has selected for small viral oncopr

73 Identification of this tumor virus has led to new opportunities for early diagn

74 The study of DNA tumor viruses has been invaluable in uncovering the cell

75 The origins of replication of DNA tumor viruses have a highly conserved feature, namely, m

76 Thus, tumor viruses have proved to be invaluable aids in ident

77 Studies of DNA tumor viruses have provided important insights into fund

78 DNA tumor viruses have provided major insights into how canc

79 tumors overexpressing HER2 in mouse mammary tumor virus/HER2 allograft models.

80 This provirus, designated as human mammary tumor virus (HMTV), was 95% homologous to MMTV and revea

81 s for the identification of additional human tumor viruses--human T-cell leukemia virus type 1, hepat

82 Intervention by this DNA tumor virus in cellular translational controls is likely

83 n-Barr virus (EBV) is one of the predominant tumor viruses in humans, but so far no therapeutic or pr

84 Later identification of mammalian tumor viruses in the 1930s by Richard Shope and John Bit

85 Here, we identify the oncogenes of the DNA tumor viruses, including E7 from human papillomavirus (H

86 Infections with DNA tumor viruses, including members of the polyomavirus fam

87 are rare in mammals; however, several human tumor viruses, including the papillomaviruses and the ga

88 ns of transforming proteins from several DNA tumor viruses, including two papillomaviruses and two po

89 s idea, results with several different human tumor viruses indicate that their oncogenic potential de

90 uch advancement may also provide insights on tumor virus-induced tumorigenesis in general and help th

91 NK cells against different targets including tumor, virus-infected, and immature dendritic cells.

92 teraction with specific ligands expressed on tumor/virus-infected cells, thus contributing to immune

93 papillomavirus (PV) is a double-stranded DNA tumor virus infecting cervix, mouth, and throat tissues.

94 Papillomavirus (PV) is a double-stranded DNA tumor virus infecting the cutaneous and mucosal epitheli

95 the IFN pathway in the control of this human tumor virus infection.

96 Epstein-Barr virus (EBV), as the first human tumor virus, infects more than 90% of the human populati

97 ypes, including wingless-type murine mammary tumor virus integration site (WNT) pathway subtype, Soni

98 cyclin D1 and wingless-related mouse mammary tumor virus integration site 10b (Wnt10b) in 3T3-L1 cell

99 ome inducible by wingless-type mouse mammary tumor virus integration site family member (WNT)/beta-ca

100 here wnt refers to the wingless-type mammary tumor virus integration site family of proteins), that a

101 ween mesenchymal Wingless-type Mouse Mammary Tumor Virus integration site family, member 10B (Wnt10b)

102 tion of Wingless-related MMTV (mouse mammary tumor virus) integration site 3 (WNT3) by ingrowing axon

103 rphogen Wingless-related MMTV (mouse mammary tumor virus) integration site 3 (WNT3).

104 canonical wingless-type MMTV (mouse mammary tumor virus) integration site family (WNT) signaling pat

105 e best-studied oncoproteins encoded by a DNA tumor virus is adenovirus E1A, which modifies the functi

106 establishment of a latent reservoir by human tumor viruses is a vital step in initiating cellular tra

107 A common feature of human tumor viruses is their ability to stimulate proliferatio

108 sarcoma-associated herpesvirus (KSHV), a DNA tumor virus, is an etiological agent linked to several h

109 rus saimiri (HVS), which is a T-lymphotropic tumor virus, is constitutively targeted to lipid rafts a

110 us retrovirus-K (HERV-K) human mouse mammary tumor virus-like 2 (HML-2) is the most recently active e

111 ein 0 (ICP0) promoter, and the mouse mammary tumor virus long terminal repeat (MMTV-LTR).

112 ions, under the control of the mouse mammary tumor virus long terminal repeat promoter, develop multi

113 ary epithelial cells using the mouse mammary tumor virus long terminal repeat.

114 alizing CSF-1R antibody in the mouse mammary tumor virus long-terminal region-driven polyoma middle T

115 3beta under the control of the mouse mammary tumor virus-long terminal repeat develop mammary tumors

116 e whey acidic protein (WAP) or mouse mammary tumor virus-long terminal repeat promoters, develop mamm

117 e steroid responsive MMTV-LTR (mouse mammary tumor virus-long terminal repeat), we show that BRG1 and

118 ositions of nucleosomes on the mouse mammary tumor virus LTR, and additionally, we characterized the

119 In these animals, mouse mammary tumor virus LTR-driven expression of the constitutively

120 , our data provide the first evidence that a tumor virus may use a viral protein to interfere with mi

121 results provide new insights into how human tumor viruses may manipulate cellular DNA-damage respons

122 at the oncoproteins encoded by the small-DNA tumor viruses may use this mechanism to induce c-Myc, wh

123 yk has a positive function in murine mammary tumor virus-mediated tumorigenesis.

124 summer marks the 51st anniversary of the DNA tumor virus meetings.

125 mbrane targeting of the B-type mouse mammary tumor virus (MMTV) and C-type HIV-1, which assemble in t

126 Two other betaretroviruses, mouse mammary tumor virus (MMTV) and human endogenous retrovirus type

127 APOBEC3 restricts infection by mouse mammary tumor virus (MMTV) and murine leukemia virus (MLV) and t

128 , which control infection with mouse mammary tumor virus (MMTV) and murine leukemia virus (MuLV) via

129 on on two different reporters, mouse mammary tumor virus (MMTV) and prostate-specific antigen (PSA).

130 Integration of mouse mammary tumor virus (MMTV) at the common integration site Int6 o

131 lls stably transfected with an mouse mammary tumor virus (MMTV) chloramphenicol acetyltransferase rep

132 Mouse mammary tumor virus (MMTV) encodes a Rev-like protein, Rem, whic

133 65)b, under the control of the mouse mammary tumor virus (MMTV) enhancer/promoter.

134 cogenic viruses, including the mouse mammary tumor virus (MMTV) envelope (Env).

135 ith sequences derived from the mouse mammary tumor virus (MMTV) envelope glycoprotein, influenza viru

136 The mouse mammary tumor virus (MMTV) Gag protein directs the assembly in t

137 Mouse mammary tumor virus (MMTV) has been classified as a simple retro

138 with sequences similar to the mouse mammary tumor virus (MMTV) has been shown, but convincing eviden

139 3 (mA3) restricts infection by mouse mammary tumor virus (MMTV) in its natural host.

140 s, including HIV in humans and mouse mammary tumor virus (MMTV) in mice.

141 Mouse mammary tumor virus (MMTV) induces breast cancer with almost 100

142 wed that IFN-gamma elicited by mouse mammary tumor virus (MMTV) infection in I/LnJ mice stimulated pr

143 ed that they were resistant to mouse mammary tumor virus (MMTV) infection.

144 Mouse mammary tumor virus (MMTV) is a complex murine retrovirus that e

145 Mouse mammary tumor virus (MMTV) is a complex retrovirus that encodes

146 Mouse mammary tumor virus (MMTV) is a milk-transmitted betaretrovirus

147 Exogenous mouse mammary tumor virus (MMTV) is transmitted via the milk from infe

148 expressing Sim2s driven by the mouse mammary tumor virus (MMTV) long terminal repeat (LTR) promoter w

149 ) protein under control of the mouse mammary tumor virus (MMTV) long terminal repeat promoter.

150 oncogene under control of the mouse mammary tumor virus (MMTV) long-terminal repeat (MMT mice).

151 the maximal effect of DEX in a mouse mammary tumor virus (MMTV) luciferase reporter transactivation a

152 otein of the murine retrovirus mouse mammary tumor virus (MMTV) orchestrates the assembly of immature

153 Using the mouse mammary tumor virus (MMTV) promoter as a model, we probed the st

154 endent transcription from the murine mammary tumor virus (MMTV) promoter by p65 and E1A was investiga

155 ssion under the control of the mouse mammary tumor virus (MMTV) promoter in a transgenic mouse model

156 sponse was investigated on the mouse mammary tumor virus (MMTV) promoter in different chromatin confi

157 ed human SMO (SmoM2) under the mouse mammary tumor virus (MMTV) promoter in transgenic mice leads to

158 Here, the basic features of mouse mammary tumor virus (MMTV) promoter nucleosomal arrays reconstit

159 the interaction of PR with the mouse mammary tumor virus (MMTV) promoter reconstituted into chromatin

160 otein under the control of the mouse mammary tumor virus (MMTV) promoter results in mammary gland hyp

161 We used the mouse mammary tumor virus (MMTV) promoter to target expression of a ki

162 ranscriptional activation of a mouse mammary tumor virus (MMTV) promoter-driven luciferase construct

163 etion of Ppm1d in mice bearing mouse mammary tumor virus (MMTV) promoter-driven oncogenes Erbb2 (also

164 Mouse mammary tumor virus (MMTV) promoter-driven Ptn expressed in MMTV

165 positioned nucleosomes in the mouse mammary tumor virus (MMTV) promoter.

166 t ERalpha under control of the mouse mammary tumor virus (MMTV) promoter.

167 epithelial cells driven by the mouse mammary tumor virus (MMTV) promoter.

168 ene, tva, under control of the mouse mammary tumor virus (MMTV) promoter.

169 orally transmitted retrovirus mouse mammary tumor virus (MMTV) requires the intestinal microbiota fo

170 emogenic virus is a variant of mouse mammary tumor virus (MMTV) that causes thymic lymphomas rather t

171 have shown that CDP represses mouse mammary tumor virus (MMTV) transcription in tissue culture cells

172 The beta retrovirus mouse mammary tumor virus (MMTV) uses transferrin receptor 1 (TfR1) to

173 B leukemogenic virus (TBLV), a mouse mammary tumor virus (MMTV) variant, often induces T-cell leukemi

174 ommon integration site for the mouse mammary tumor virus (MMTV) was identified (designated Int7) in f

175 a transcriptional repressor of mouse mammary tumor virus (MMTV), a betaretrovirus that is a paradigm

176 a, c-myc, and those encoded by mouse mammary tumor virus (MMTV), a glucocorticoid-responsive retrovir

177 shows for the first time that mouse mammary tumor virus (MMTV), a mammalian retrovirus that assemble

178 Mouse mammary tumor virus (MMTV), a well-characterized retrovirus that

179 Many retroviruses, including mouse mammary tumor virus (MMTV), are transmitted most efficiently thr

180 te sheep retrovirus (JSRV) and mouse mammary tumor virus (MMTV), as well as many endogenous retroviru

181 ry-specific deletion inhibited mouse mammary tumor virus (MMTV)- PyMT- and MMTV- Wnt1-driven mammary

182 We intercrossed mouse mammary tumor virus (MMTV)-c-neu transgenic mice with beta3 or b

183 s as judged by findings with a mouse mammary tumor virus (MMTV)-c-rel transgenic mouse model, in whic

184 ammary epithelial cells of the mouse mammary tumor virus (MMTV)-Cre Brca1 conditional exon 11 deletio

185 The mouse mammary tumor virus (MMTV)-Cre-mediated, epithelial-specific abl

186 In the mouse mammary tumor virus (MMTV)-driven polyoma middle-T oncogene stra

187 Mouse mammary tumor virus (MMTV)-ErbB2 mice lacking PKCdelta (deltaKO)

188 of HER2/Neu in breast cancer, mouse mammary tumor virus (MMTV)-Her2/neu transgenic mice that develop

189 2 overexpression, we generated mouse mammary tumor virus (MMTV)-Hoxb7 transgenic mice, and then cross

190 creases mammary cancer risk in mouse mammary tumor virus (MMTV)-infected females even after multiple

191 e previously reported a 660-bp mouse mammary tumor virus (MMTV)-like env gene sequence in approximate

192 The mouse mammary tumor virus (MMTV)-MT model of breast cancer has been im

193 In a mouse mammary tumor virus (MMTV)-MYC transgenic mouse model of breast

194 A total of 50 uniparous mouse mammary tumor virus (MMTV)-neu and 50 nuliparous MMTV-wnt1 trans

195 its the formation of tumors in mouse mammary tumor virus (MMTV)-Neu mice.

196 mor formation in xenograft and mouse mammary tumor virus (MMTV)-neu mouse models in a manner associat

197 PA), inhibits lung metastases in the mammary tumor virus (MMTV)-Neu transgenic mouse breast cancer mo

198 ogenic signaling in the NeuYD [mouse mammary tumor virus (MMTV)-Neu(ndl)-YD5] mammary tumor model.

199 When mouse mammary tumor virus (MMTV)-neu-induced tumor cells were mixed wi

200 st tumorigenesis, we generated mouse mammary tumor virus (MMTV)-NeuNT transgenic mice lacking one or

201 crossing the mutation into the mouse mammary tumor virus (MMTV)-polyoma virus middle T (PyV-mT) trans

202 ation of mammary tumors in the mouse mammary tumor virus (MMTV)-polyoma virus middle T (PyVT) genetic

203 /+) mice were crossed with the mouse mammary tumor virus (MMTV)-Polyoma virus middle T antigen (PyMT)

204 F transcription factors in the mouse mammary tumor virus (MMTV)-polyomavirus middle T oncoprotein (Py

205 tant knock-in (R175H) mice and mouse mammary tumor virus (MMTV)-Wnt-1 transgenic (mWnt-1) mice to spe

206 Here, we have used mouse mammary tumor virus (MMTV)-Wnt1 transgenic mice, which develop s

207 expressed in mammary tumors of mouse mammary tumor virus (MMTV)-Wnt1-transgenic mice and in aggressiv

208 fection with a betaretrovirus, mouse mammary tumor virus (MMTV).

209 ncoded within the env gene of murine mammary tumor virus (MMTV).

210 transcriptional control of the mouse mammary tumor virus (MMTV).

211 lactation and is expressed in mouse mammary tumor virus (MMTV)/PyMT tumors.

212 ted c-neu oncogene driven by a mouse mammary tumor virus (MMTV-neu) in vivo, we show that ErbB2 overe

213 rous, ErbB2/Neu-overexpressing mouse mammary tumor virus (MMTV-Neu) mice have shown that parity induc

214 The absence of endogenous mouse mammary tumor viruses (MMTVs) in the congenic mouse strain, BALB

215 illustrates a distinct mechanism by which a tumor virus modulates vasculature to promote tumorigenes

216 irus (EBV) was discovered as the first human tumor virus more than 50 years ago.

217 relative to MCC patients with virus-positive tumors, virus-negative MCC patients had significantly in

218 increases NOTCH1 activation in mouse mammary tumor virus-neu mice.

219 celerated tumor progression in mouse mammary tumor virus/neu transgenic mice by inhibiting apoptosis

220 terminal (Cys(2)HisCys) ZBD of Mouse Mammary Tumor Virus nucleocapsid protein (MMTV NCp10) were resis

221 ions in chromosome 22, including the chicken tumor virus number 10 regulator of kinase (Crk)-like (Cr

222 Tumor viruses often target DNA repair machinery to achie

223 Many DNA tumor virus oncogenes are capable of activating and high

224 DNA tumor virus oncoproteins reduce Rb function by either in

225 onal activation from chromatin mouse mammary tumor virus or endogenous promoters in vivo.

226 In cells infected with DNA tumor viruses, p53 is bound to the viral tumor antigens

227 In the mouse mammary tumor virus-Polyoma Middle T (MMTV-PyMT) model of lumina

228 ors have developed, we use the mouse mammary tumor virus-Polyoma Middle T (MMTV-PyMT), which mimics R

229 In mouse mammary tumor virus-polyoma middle T (PyMT) breast cancer mouse

230 ent, we established cohorts of mouse mammary tumor virus-polyoma middle T (PyMT) PAR1(-/-) and PAR2(-

231 east cancer development in the mouse mammary tumor virus-polyoma middle T-antigen model.

232 generated and crossed with the Mouse Mammary Tumor Virus-Polyoma Middle T-Antigen mouse.

233 ls of Kiss1r gene knockout and mouse mammary tumor virus-polyoma virus middle T antigen (MMTV-PyMT)-i

234 itumor response, we engineered mouse mammary tumor virus-polyoma virus middle T antigen mice with end

235 increased pAkt levels in total mouse mammary tumor virus-polyoma virus middle T antigen tumor lysates

236 mice in the background of the mouse mammary tumor virus/polyoma virus middle T oncogene (MMTV-PyMT)

237 d AIB1(-/-) mice harboring the mouse mammary tumor virus-polyomavirus middle T (PyMT) transgene.

238 table (4T1) and autochthonous (mouse mammary tumor virus-polyomavirus middle T Ag (MMTV-PyMT)) mouse

239 br2MGKO mice were mated to the mouse mammary tumor virus-polyomavirus middle T antigen (PyVmT) transg

240 del of luminal breast cancer [murine mammary tumor virus promoter (MMTV-NIC)].

241 2-myristate-13-acetate-induced mouse mammary tumor virus promoter activity and phorbol 12-myristate 1

242 e-dependent PR activation of a mouse mammary tumor virus promoter in both prostate (PC-3) and breast

243 ability to associate with the mouse mammary tumor virus promoter in organized chromatin.

244 te hSwi-Snf complexes bound to mouse mammary tumor virus promoter nucleosomal arrays, a natural targe

245 lex on individual, single-copy mouse mammary tumor virus promoter nucleosomal arrays.

246 ear factor 1 (NF1) to bind the mouse mammary tumor virus promoter organized as regular chromatin in v

247 epressed the activation of the mouse mammary tumor virus promoter related to overexpression of the tr

248 receptor, to a tandem array of mouse mammary tumor virus promoter sites in live cells, obtaining an e

249 (KDACis) potently repress the mouse mammary tumor virus promoter through transcriptional mechanisms

250 oma middle T antigen under the mouse mammary tumor virus promoter were combined with mice that have d

251 C-->U substitution within the mouse mammary tumor virus promoter, one located within each GRE half-s

252 ncers in mice transgenic for a mouse mammary tumor virus promoter-driven polyomavirus middle T antige

253 A transcriptionally inert Mouse Mammary Tumor Virus promoter-region nucleosome (MMTV-D) has grea

254 gment under the control of the mouse mammary tumor virus promoter.

255 A-isoform interactions at the mouse mammary tumor virus promoter.

256 (T1) under the control of the mouse mammary tumor virus promoter.

257 ion response elements from the mouse mammary tumor virus promoter.

258 (pMT) under the control of the mouse mammary tumor virus promoter.

259 cleosomes (from yeast GAL10 or mouse mammary tumor virus promoters).

260 ity of the folded structure of mouse mammary tumor virus pseudoknot in the presence of different amou

261 ucleotides (ASOs) in the MMTV (mouse mammary tumor virus)-PyMT mouse mammary carcinoma model results

262 In the case of tumor viruses, recent findings suggest that alterations

263 d utilizes a conditional allele of the avian tumor virus receptor A (TVA), which allows infection of

264 It is unclear how DNA tumor viruses regulate these enzymes and how these inter

265 This study reveals a mechanism by which tumor viruses reshape the cellular response to DNA damag

266 rn based on decades of study on an avian RNA tumor virus, Rous sarcoma virus (RSV).

267 Consequently, human tumor viruses should serve as powerful tools for deciphe

268 DNA tumor viruses such as Kaposi's sarcoma-associated herpes

269 DNA tumor viruses such as simian virus 40 (SV40) express dom

270 are tolerized to an endogenous mouse mammary tumor virus superantigen either by deletion or TCR revis

271 Mouse mammary tumor virus superantigens (vSAGs) are notorious for defy

272 Although the small DNA tumor virus SV40 (simian virus 40) fails to replicate in

273 KS.IMPORTANCE Here we show that HHV-8, a DNA tumor virus that causes Kaposi's sarcoma, infects three

274 Epstein-Barr virus (EBV) is a tumor virus that establishes lifelong infection in most

275 ted herpesvirus (KSHV) is a lymphotropic DNA tumor virus that induces Kaposi's sarcoma and AIDS-relat

276 Adenovirus is a small DNA tumor virus that is a global human pathogen and key biom

277 KSHV is a human tumor virus that maintains its genome as a plasmid in ly

278 Tumor viruses that depend on tumors for replication and

279 Gammaherpesviruses (GHVs) are DNA tumor viruses that establish lifelong, chronic infection

280 ) and Epstein-Barr virus (EBV) are human DNA tumor viruses that express nuclear antigens [latency-ass

281 so through mechanisms distinct from classic tumor viruses that express transforming viral oncoprotei

282 eplication-competent exogenous mouse mammary tumor viruses that failed to induce mammary tumors in su

283 Thus, like many of the small DNA tumor viruses, the first protein expressed upon HCMV inf

284 The mechanism employed by DNA tumor viruses to inhibit p53-dependent transcription fro

285 re micromolar antagonists in a mouse mammary tumor virus transactivation assay.

286 the mid-1970s, the molecular basis by which tumor viruses transform cells into a malignant state was

287 retation of the p53-Tag complexes and of DNA tumor virus transformation in general.

288 also the first demonstration of a human DNA tumor virus upregulating TLR3, a TLR that thus far has b

289 e provided a mechanistic framework for how a tumor virus using the epigenetic machinery can act in a

290 d AIB1(-/-) mice harboring the mouse mammary tumor virus/v-Ha-ras (ras) transgene that induces breast

291 In the middle of the 20th century, animal tumor viruses were heralded as possible models for under

292 uman papillomaviruses (HPVs) are small dsDNA tumor viruses, which are the etiologic agents of most ce

293 the carcinogenic properties of various human tumor viruses, which, in aggregate, are etiologically as

294 gonist of the wingless-related mouse mammary tumor virus (WNT) signaling pathway, is one endometrial

295 B-231 breast cancer cells, and mouse mammary tumor virus-Wnt-1 mammary tumor-derived cells, implicati

296 n in mammary tumors arising in mouse mammary tumor virus-Wnt-1 transgenic mice.

297 ontext of the well-established mouse mammary tumor virus-Wnt-1 transgenic mouse.

298 r efficacy was shown using the mouse mammary tumor virus-Wnt1 tumor model under dosing conditions tha

299 MVMi, MVMc, MVM-G17, tumor virus X (TVX), canine parvovirus (CPV), porcine pa

300 Yaba monkey tumor virus (YMTV) encodes a related family member, 14L,